@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0736: (2015-12-04 )
MTRKIILQLLISIVIIFTLASAFVFVVVCINKGKPERKDKLYEIDAAHSSWVQTIAYYLVKPILESALDRYIEKHGLIEYLKEIIQQKVEKGSINFYEIIEGSGSRAFCGQEVVLQMYKISDNLATPLPLPKQTSDVTLVIGQDNQREVGLGVIGMKEGGERVVTINNIANKNEVNFNSYYIKLIEVKDKYPDSVNSMMIFNELINKTGKQVKCGDRVSVKYSLMGHDGEYIIKNQTVQFKVGNKKVPLAMELGVIGMKEGNNRTIISPPELLNVTDDMLIENIDFDEESVSIISLSLDDKQEIAAHHSTVE
Atome Classification :
(20 SA)
--------........---.10.....------...20...---.....30........40.......---------------.50........60........70.....--------------------...80........90.......-------------------.100..--.-....110.......120.....-..130.......140------...-.....150......--.160.......170..---------.....180.......190.......200......--.210........220.......230.----..----....240.....--..250.......260.......270.......280.....------..290.......300.......310-----------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------M
T
R
K
I
I
L
Q
---
L
L
I
S
I
V
I
I
------
F
T
L
A
S
A
F
V
---
F
V
V
V
C
INKGKPERKDK
L
Y
E
IDA
A
H
---------------
S
S
W
V
Q
T
I
A
Y
Y
L
V
K
P
I
L
E
S
A
L
D
R
Y
I
E
K
H
G
--------------------
L
I
E
Y
L
K
E
I
I
Q
Q
K
V
E
KGS
I
N
F
Y
E
-------------------
I
IEGSG--S-RAFC
G
Q
E
V
V
L
Q
M
Y
K
ISDNLATP-LPLPKQTS
D
V
T
L
V
I-------GQD-NQ
R
E
VG
L
G
V
I
G
MKE--GG
E
R
V
V
T
INNIANKNE---------VNFN
S
Y
Y
I
K
L
I
E
VKDKYPD
S
V
N
S
M
M
I
F
N
E
L
I
N
KT--G
K
Q
-
V
KCG
D
R
V
S
V
K
Y
S
L
MGHDG
E
Y
I
I
----KN----
Q
T
V
Q
F
K
VGNKKV--
P
L
A
M
E
L
G
V
I
G
MKEGNN
R
T
IISP
P
E
L
LNV
T
D
D
M
L
IENIDFD------EE
S
V
S
I
I
S
L
SLD
D
K
Q
E
I
A
A
HHSTVE-----------------------------------------
54
Fugue
74.07
18%
-47
- C5 -
4D7E
1
?
A:
[1-413]
ME
T
L
L
V
VG
A
G
P
K
A
L
A
V
---
A
A
K
S
H
V
L
R
------
Q
L
G
L
S
A
P
R
---
V
I
A
V
E
A
H
A
V
G
G
N
W
L
A
S
G
G
W
T
D
G
R
H
RLGTSPEKDIGFPYH
S
T
W
A
R
G
H
N
R
E
I
N
E
A
M
M
A
F
S
W
T
S
F
L
V
E
H
G
T
Y
A
E
W
I
D
R
GRPSPQ
H
H
V
W
A
K
Y
L
Q
W
V
A
R
K
I
D
L
E
L
V
L
G
K
V
R
T
I
R
QG
W
S
V
E
V
A
GA
T
T
E
L
E
A
D
G
L
M
I
T
G
P
G
QS
T
-
K
A
L
A
A
H
P
R
V
L
S
I
A
E
F
W
D
-
L
A
G
K
-
R
K
L
P
--
I
S
S
R
A
A
V
I
-------
G
G
G
-
E
T
A
G
S
A
L
D
E
L
V
R
H
E
------
M
L
T
I
S
V
I
S
P
M
A
S
---------
Y
F
E
N
S
L
F
S
D
P
T
K
W
N
A
L
------
S
I
Q
E
R
R
D
V
I
R
R
T
--
D
R
G
-
V
F
---
S
V
R
V
Q
E
S
L
L
G
D
N
R
V
H
H
L
----
Q
G
----
R
V
T
R
I
V
G
Q
G
D
G
V
--
A
V
T
L
R
N
E
M
R
A
D
Q
V
H
N
F
D
L
V
V
D
A
T
G
G
----
Q
P
L
W
F
L
D
L
-
F
D
------
S
E
S
A
D
L
L
E
L
A
V
G
G
P
L
T
Q
Q
R
I
E
S
S
I
G
YDLAVTGLG
A
K
L
Y
L
PNMAALAQGPGFPNLSC
L
G
E
L
S
D
R
V
L
R
44
HHSearch
69.78
15%
-54
- C7 -
2AWG
-
FKBP8_HUMAN
A:
[101-202]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
R
K
K
T
L
V
P
G
P
PG
S
S
R
-
P
V
K
G
Q
V
V
T
V
H
L
Q
T
S
L
E
N
G
T
R
V
Q
----
E
E
----
P
E
L
V
F
T
L
G
D
C
D
V
--
I
Q
A
L
D
L
S
V
P
L
M
D
V
G
E
T
A
M
V
T
A
D
S
K
Y
C
Y
G
P
Q
G
R
S
-
P
Y
I
P
P
H
------
A
A
L
C
L
E
V
T
L
K
T
A
V
D
----------------------------------------------------
43
HHSearch
69.55
20%
-63
- C7 -
1KT0
-
FKBP5_HUMAN
A:
[33-138]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
K
I
V
---------
T
-
P
M
I
G
D
K
V
Y
V
H
Y
K
G
K
L
-----
F
D
----
S
------
P
F
V
F
S
L
G
K
G
Q
V
--
I
K
A
W
D
I
G
V
A
T
M
K
R
G
E
I
C
H
L
L
C
K
P
E
Y
A
Y
G
S
A
G
S
-
L
P
K
I
P
S
N
------
A
T
L
F
F
E
I
E
L
L
D
F
K
G
E
D
L
F
E
D
G
G
I
I
R
-----------------------------------------
7
PsiBlast_PDB
69.08
28%
-66
- C7 -
3UQB
1
A:
[101-183]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
E
S
G
L
K
Y
E
D
L
T
E
G
S
--
G
A
E
-
A
R
A
G
Q
T
V
S
V
H
Y
T
G
W
L
T
D
G
Q
K
F
G
SSKD
R
N
-----
P
F
A
F
V
L
G
G
G
M
V
--
I
K
G
W
D
E
G
V
Q
G
M
K
V
G
G
V
R
R
L
T
I
P
P
Q
L
G
Y
G
A
R
G
A
G
G
V
I
P
P
N
A
------
T
L
V
F
E
V
E
L
L
D
V
-------------------------------------------------------
10
PsiBlast_PDB
68.48
28%
-57
- C7 -
4GIV
2
SMT3_YEAST
A:
[101-183]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
E
S
G
L
K
Y
E
D
L
T
E
G
S
--
G
A
E
-
A
R
A
G
Q
T
V
S
V
H
Y
T
G
W
L
T
D
G
Q
K
F
G
SSKD
R
N
----
D
P
F
A
F
V
L
G
G
G
M
V
--
I
K
G
W
D
E
G
V
Q
G
M
K
V
G
G
V
R
R
L
T
I
P
P
Q
L
G
Y
G
A
R
G
A
G
G
V
I
P
P
N
A
------
T
L
V
F
E
V
E
L
L
D
V
-------------------------------------------------------
1
PsiBlast_PDB
68.05
28%
-58
- C7 -
3UQA
2
A:
[101-183]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
E
S
G
L
K
Y
E
D
L
T
E
G
S
--
G
A
E
-
A
R
A
G
Q
T
V
S
V
H
Y
T
G
W
L
T
D
G
Q
K
F
D
SSKD
R
N
----
D
P
F
E
F
V
L
G
G
G
M
V
--
I
K
G
W
D
E
G
V
Q
G
M
K
V
G
G
V
R
R
L
T
I
P
P
Q
L
G
Y
G
A
R
G
A
G
G
V
I
P
P
N
A
------
T
L
V
F
E
V
E
L
L
D
V
-------------------------------------------------------
6
PsiBlast_PDB
68.00
28%
-58
- C7 -
3VAW
1
A:
[101-183]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
E
S
G
L
K
Y
E
D
L
T
E
G
S
--
G
A
E
-
A
R
A
G
Q
T
V
S
V
H
Y
T
G
W
L
T
D
G
Q
K
F
D
SSKD
R
N
----
D
P
F
A
F
V
L
G
G
G
M
V
--
I
K
G
W
D
E
G
V
Q
G
M
K
V
G
G
V
R
R
L
T
I
P
P
Q
L
G
Y
G
A
R
G
A
G
G
V
I
P
P
N
A
------
T
L
V
F
E
V
E
L
L
D
V
-------------------------------------------------------
39
HHSearch
67.75
16%
-40
* C7 *
1YAT
1
FKBP_YEAST
A:
[4-111]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
G
N
V
K
I
D
R
I
S
P
G
D
--
G
A
T
F
P
K
T
G
D
L
V
T
I
H
Y
T
G
T
L
E
N
G
Q
K
F
D
----
S
S
VDRG
S
P
F
Q
C
N
I
G
V
G
Q
V
--
I
K
G
W
D
V
G
I
P
K
L
S
V
G
E
K
A
R
L
T
I
P
G
P
Y
A
Y
G
P
R
G
F
-
P
G
L
I
P
P
N
------
S
T
L
V
F
D
V
E
L
L
K
V
N
-----------------------------------------------------
46
HHSearch
67.33
25%
-37
- C7 -
3UF8
1
A:
[100-207]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
T
E
S
G
L
K
Y
E
D
L
T
E
G
S
--
G
A
E
-
A
R
A
G
Q
T
V
S
V
H
Y
T
G
W
L
T
D
G
Q
K
F
D
----
S
S
KDRN
D
P
F
A
F
V
L
G
G
G
M
V
--
I
K
G
W
D
E
G
V
Q
G
M
K
V
G
G
V
R
R
L
T
I
P
P
Q
L
G
Y
G
A
R
G
A
-
A
G
V
I
P
P
N
------
A
T
L
V
F
E
V
E
L
L
D
V
------------------------------------------------------
51
Fugue
67.26
16%
-75
* C5 *
4NTC
1
?
A:
[2-326]
--------
M
S
I
G
K
L
L
S
NG
A
L
L
V
D
V
L
I
I
GAG
P
A
G
L
S
T
A
T
G
L
A
R
Q
L
H
T
A
V
V
F
D
S
G
V
Y
R
N
A
K
T
------
Q
H
---------------
M
H
N
V
L
G
W
D
H
R
N
P
A
E
L
R
A
A
G
R
A
D
L
T
T
R
Y
S
--------------------
T
I
Q
F
Q
N
S
T
I
E
A
I
R
Q
V
E
T
N
Q
L
F
E
-------------------
A
R
D
N
E
G
----
H
S
W
Y
G
R
K
V
V
L
-
A
T
G
V
R
D
---
I
P
-
L
D
I
E
G
Y
S
E
C
W
A
N
G
I
YHCLFCD
G
Y
E
-
E
R
G
Q
E
T
V
G
V
L
A
L
G
P
IA
N
P
A
R
A
L
H
L
A
R
M
A
L
R
L
S
---------
E
S
V
T
I
Y
T
N
G
N
E
Q
L
A
K
E
I
Q
Q
A
A
E
E
S
P
V
G
A
S
G
L
K
F
E
--
A
R
P
-
I
R
R
F
E
K
G
D
V
A
K
T
V
I
V
H
L
G
E
S
E
S
----
K
T
----
E
G
F
L
V
Y
N
P
Q
T
E
V
N
G
P
F
A
K
Q
L
A
-
L
N
M
T
E
G
G
D
--
I
L
T
T
P
P
F
Y
E
T
S
V
P
G
V
F
A
V
G
D
C
A
TPLKA
V
T
P
A
V
S
M
G
S
L
A
A
G
G
L
V
A
Q
L
Q
A
Q
A
L
-------------------------------------------
2
PsiBlast_PDB
67.22
28%
-59
- C7 -
4DZ3
8
?
A:
[5-87]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
E
S
G
L
K
Y
E
D
L
T
E
G
S
--
G
A
E
-
A
R
A
G
Q
T
V
S
V
H
Y
T
G
W
L
T
D
G
Q
K
F
D
SSKD
R
N
----
D
P
F
A
F
V
L
G
G
G
H
V
--
I
K
G
W
D
E
G
V
Q
G
M
K
V
G
G
V
R
R
L
T
I
P
P
Q
L
G
Y
G
A
R
G
A
G
G
V
I
P
P
N
A
------
T
L
V
F
E
V
E
L
L
D
V
-------------------------------------------------------
8
PsiBlast_PDB
66.67
28%
-57
- C7 -
4FN2
1
SMT3_YEAST
A:
[101-183]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
E
S
G
L
K
Y
E
D
L
T
E
G
S
--
G
A
E
-
A
R
A
G
Q
T
V
S
V
H
Y
T
G
W
L
T
D
G
Q
K
F
G
SSKD
R
N
----
D
P
F
A
F
V
L
G
G
G
M
V
--
I
K
G
W
D
E
G
V
Q
G
M
K
V
G
G
V
R
R
L
T
I
P
P
Q
L
G
Y
G
A
R
G
A
G
G
V
I
P
P
N
A
------
T
L
V
F
E
V
E
L
L
D
V
-------------------------------------------------------
3
PsiBlast_PDB
65.62
28%
-63
- C7 -
4DZ2
2
?
A:
[5-87]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
E
S
G
L
K
Y
E
D
L
T
E
G
S
--
G
A
E
-
A
R
A
G
Q
T
V
S
V
H
Y
T
G
W
L
T
D
G
Q
K
F
D
SSKD
R
N
----
D
P
F
A
F
V
L
G
G
G
M
V
--
I
K
G
W
D
E
G
V
Q
G
M
K
V
G
G
V
R
R
L
T
I
P
P
Q
L
G
Y
G
A
G
G
A
G
G
V
I
P
P
N
A
------
T
L
V
F
E
V
E
L
L
D
V
-------------------------------------------------------
28
HHSearch
65.60
20%
-39
- C7 -
1Q6H
-
FKBA_ECOLI
A:
[117-222]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
S
S
T
G
L
V
Y
Q
V
V
E
A
G
K
--
G
E
A
-
P
K
D
S
D
T
V
V
V
N
Y
K
G
T
L
I
D
G
K
E
F
D
----
N
S
YTRG
E
P
L
S
F
R
L
D
--
G
V
--
I
P
G
W
T
E
G
L
K
N
I
K
K
G
G
K
I
K
L
V
I
P
P
E
L
A
Y
G
K
A
G
V
--
P
G
I
P
P
N
------
S
T
L
V
F
D
V
E
L
L
D
V
K
-----------------------------------------------------
9
PsiBlast_PDB
65.53
28%
-56
- C7 -
4G50
2
SMT3_YEAST
A:
[101-183]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
E
S
G
L
K
Y
E
D
L
T
E
G
S
--
G
A
E
-
A
R
A
G
Q
T
V
S
V
H
Y
T
G
W
L
T
D
G
Q
K
F
G
SSKD
R
N
----
D
P
F
A
F
V
L
G
G
G
M
V
--
I
K
G
W
D
E
G
V
Q
G
M
K
V
G
G
V
R
R
L
T
I
P
P
Q
L
G
Y
G
A
R
G
A
G
G
V
I
P
P
N
A
------
T
L
V
F
E
V
E
L
L
D
V
-------------------------------------------------------
40
HHSearch
65.36
20%
-37
- C7 -
3UF8
1
SMT3_YEAST
A:
[84-208]
---------------------------------------------------------------------------------------------------
N
D
I
I
E
A
H
R
E
Q
I
G
--------------------
G
S
T
V
V
-------
T
T
E
S
G
L
K
Y
E
D
-------------------
L
T
E
G
S
G
--
A
-
E
A
R
A
G
Q
T
V
S
V
H
Y
T
G
W
L
T
-
D
G
Q
K
F
D
S
S
K
D
R
N
D
P
F
A
F
V
L
-------
G
G
G
M
V
I
K
G
W
D
E
G
V
Q
G
M
K
V
--
G
G
V
R
R
L
T
I
P
P
Q
L
G
Y
G
A
RGAAGVIPP
N
A
T
L
V
F
E
V
E
L
L
D
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
64.92
28%
-58
- C7 -
3UF8
1
A:
[101-183]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
E
S
G
L
K
Y
E
D
L
T
E
G
S
--
G
A
E
-
A
R
A
G
Q
T
V
S
V
H
Y
T
G
W
L
T
D
G
Q
K
F
D
SSKD
R
N
----
D
P
F
A
F
V
L
G
G
G
M
V
--
I
K
G
W
D
E
G
V
Q
G
M
K
V
G
G
V
R
R
L
T
I
P
P
Q
L
G
Y
G
A
R
G
A
A
G
V
I
P
P
N
A
------
T
L
V
F
E
V
E
L
L
D
V
-------------------------------------------------------
5
PsiBlast_PDB
64.03
28%
-52
- C7 -
4GGQ
2
SMT3_YEAST
C:
[101-183]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
E
S
G
L
K
Y
E
D
L
T
E
G
S
--
G
A
E
-
A
R
A
G
Q
T
V
S
V
H
Y
T
G
W
L
T
D
G
Q
K
F
D
SSKD
R
N
----
D
P
F
A
F
V
L
G
G
G
M
V
--
I
K
G
W
D
E
G
V
Q
G
M
K
V
G
G
V
R
R
L
T
I
P
P
Q
L
G
Y
G
A
R
G
A
G
G
V
I
P
P
N
A
------
T
L
V
F
E
V
E
L
L
D
V
-------------------------------------------------------
24
HHSearch
63.98
20%
-39
- C7 -
3OE2
2
?
A:
[113-217]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
L
A
D
G
I
L
M
T
E
L
T
P
G
T
--
G
P
K
-
P
D
A
N
G
R
V
E
V
R
Y
V
G
R
L
P
D
G
K
I
F
D
----
Q
S
T---
Q
P
Q
W
F
R
L
D
--
S
V
--
I
S
G
W
T
S
A
L
Q
N
M
P
T
G
A
K
W
R
L
V
I
P
S
D
Q
A
Y
G
A
E
G
A
-
G
D
L
I
D
P
F
------
T
P
L
V
F
E
I
E
L
I
A
V
S
Q
----------------------------------------------------
37
HHSearch
63.88
13%
-38
- C7 -
3O5Q
2
FKBP5_HUMAN
A:
[3-126]
-------------------------------------------------------------------------------------------------------
P
A
T
V
T
E
Q
G
--------------------
E
D
I
T
-------
S
K
K
D
R
G
V
L
K
I
V
-------------------
K
R
V
G
N
G
--
E
E
T
P
M
I
G
D
K
V
Y
V
H
Y
K
G
K
L
S
-
N
G
K
K
F
D
S
S
H
D
R
N
E
P
F
V
F
S
L
-------
G
K
G
Q
V
I
K
A
W
D
I
G
V
A
T
M
K
K
--
G
E
I
C
H
L
L
C
K
P
E
Y
A
Y
G
S
AGSLPKIPS
N
A
T
L
F
F
E
I
E
L
L
D
F
K
G
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------