@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0752: (2015-12-04 )
MDDNVAIVFNLTGNNPYNSFDNSTKNSRALEGVKCYSASKTEELCKVIKKRVTKKDYRENQESGQDKTPRKCKKLFKKGASPEVLTKLGELLIEQEKYYNNYIQHFLPALKREIIKSKELNLIEKIKIEQIIMKLITSDAVSKNSNESHSNAETNEQSANGADNTLSCTAENSESGNTCEETSLKCWRSLPNLRDNSQFNFGEKLLTKMDTLEPETNASELNNGSGGDSGVSLPGLSEDGLESPLGSERSNVSSILSSAEEDNNLQKEENENQMKLDQTAREELQVQENKNQVSKVSPVQPPKKKKNVEDITMQKLPMNEKKGENILPKEQLSNREFYGIFTTGCALLAIGCFVGAVVIKSRALFLGLSVIAVVFATAAVAVWYLTLPPSSKLMYTNSSPVINNERSLLHV
Atome Classification :
(20 SA)
.........10........20........30....-----....40........50........60........70........80.-.......90........100....--...110.......120....---...130.......140---.......150.......160.......170-.-......180........190.......200.......210.......220.......230....----....240-.......250.......260.......270.......280.......290.....-..300........310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MDD
N
V
A
I
V
F
NLTGNNPYNSFDNSTKNSRALE
G
V
KC-----YSAS
K
T
E
E
L
C
K
V
I
K
K
R
V
T
K
K
D
Y
RENQESGQDKT
P
R
K
C
K
K
L
F
KKGA
S
P
-
E
V
L
T
K
L
G
E
L
L
I
E
Q
E
K
Y
Y
N
N
Y
I
Q
H
F
--
L
P
A
L
K
R
E
I
I
K
SK
E
L
N
L
I
E
K
I
---
K
I
E
Q
I
I
M
K
L
I
T
S
D
AVS---KNSNESHSNAETNEQSANGADN
T
L
S
C
TAEN-S-ESGN
T
C
E
E
-
T
S
L
K
C
W
R
SLPNLRDNSQF
N
F
G
E
K
L
L
T
K
M
DTLEPET
N
A
S
ELNNGSGGDSGV-SLPG----LSEDGLE-SPLGSER
S
N
V
S
S
I
L
S
S
A
EEDNNLQKEENENQMK
L
D
Q
T
A
R
E
E
L
Q
V
QENKNQVSKVS-PVQP-PKKKK
N
V
E
D
I
T
M
Q
KLPMNEKKGENIL
P
K
E
QLSNR
E
F
Y
G
I
FTT
G
C
A
L
L
A
I
G
C
F
V
G
A
V
V
I
KS
R
A
L
F
L
G
L
S
V
I
A
V
V
F
A
T
A
A
V
A
V
W
Y
L
TLPPSS
K
L
M
YTNSSPVINNERSLLHV--
27
Fugue
81.97
17%
26
- C3 -
3DSM
1
?
A:
[1-327]
---
A
S
G
L
F
I
T
N
E
G
N
F
Q
Y
S
N
A
-----------
T
L
S
Y
-----
Y
D
P
A
T
C
E
V
E
N
E
V
F
Y
R
A
N
G
F
K
--------------------
L
G
D
V
A
Q
S
M
V
I
R
D
G
I
G
W
I
V
V
N
N
S
--------
H
V
--
I
F
A
I
D
I
N
--
T
F
K
E
V
G
R
I
T
G
F
---
T
S
P
R
Y
I
H
F
L
S
D
E
K
A
Y
V
---
T
Q
I
W
----
D
Y
R
I
F
I
I
N
P
K
T
Y
E
I
T
G
Y
I
E
C
P
D
M
D
M
E
S
G
S
T
-
E
Q
M
V
Q
Y
G
K
Y
V
Y
V
N
C
------
W
S
Y
Q
N
R
I
L
-
K
I
D
T
-
E
T
D
K
V
V
D
E
L
T
I
G
I
Q
P
T
S
L
V
M
D
K
Y
N
K
M
W
T
I
T
D
G
G
Y
E
G
S
P
Y
G
Y
E
A
P
S
L
Y
R
I
D
A
E
T
------
F
T
V
E
K
Q
F
K
F
K
L
G
D
W
P
S
E
-
V
Q
L
N
G
T
R
D
T
L
Y
W
I
N
N
D
I
W
R
M
P
--------
V
E
A
D
R
V
P
V
R
--------
P
F
L
E
F
R
D
T
K
Y
Y
G
L
T
V
N
P
---------------
N
N
G
E
V
Y
V
A
D
---
A
I
D
Y
Q
Q
Q
G
I
V
Y
R
Y
S
P
Q
G
K
L
I
D
E
F
Y
V
G
I
I
P
G
A
F
C
W
K
L
E
H
H
H
H
H
28
Fugue
54.04
10%
116
- C5 -
4JPN
-
H_BPPHS
A:
[2-76]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
A
G
F
E
N
Q
K
E
L
T
K
M
Q
L
D
N
Q
K
E
I
A
E
M
Q
N
E
T
Q
K
E
I
A
G
I
Q
-
S
A
T
S
-
R
Q
N
T
K
D
Q
V
Y
A
Q
N
E
M
L
A
Y
Q
Q
K
E
S
T
A
R
V
A
S
I
M
E
N
T
N
------------------------------------------------------------------------------
6
PsiBlast_PDB
52.82
34%
69
- C5 -
4MYK
2
?
A:
[224-273]
--------
F
G
L
T
G
K
N
T
F
F
S
F
D
V
D
S
L
K
S
S
D
M
P
G
V
S
C
PAAVG
L
S
A
Q
E
A
F
D
M
C
F
L
A
G
K
T
P
T
V
M
M
M
D
M
S
E
L
N
P
L
V
E
E
Y
R
S
P
R
V
A
V
Y
M
F
Y
H
F
-
V
L
G
F
A
T
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
52.78
34%
66
- C5 -
4MYF
2
?
A:
[224-273]
--------
F
G
L
T
G
K
N
T
F
F
S
F
D
V
D
S
L
K
S
S
D
M
P
G
V
S
C
PAAVG
L
S
A
Q
E
A
F
D
M
C
F
L
A
G
K
T
P
T
V
M
M
M
D
M
S
E
L
N
P
L
V
E
E
Y
R
S
P
R
V
A
V
Y
M
F
Y
H
F
-
V
L
G
F
A
T
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
51.73
34%
77
- C5 -
4MYL
-
?
A:
[224-273]
--------
F
G
L
T
G
K
N
T
F
F
S
F
D
V
D
S
L
K
S
S
D
M
P
G
V
S
C
PAAVG
L
S
A
Q
E
A
F
D
M
C
F
L
A
G
K
T
P
T
V
M
M
M
D
M
S
E
L
N
P
L
V
E
E
Y
R
S
P
R
V
A
V
Y
M
F
Y
H
F
-
V
L
G
F
A
T
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
49.90
34%
74
- C5 -
2A0M
1
?
A:
[224-273]
--------
F
G
L
T
G
K
N
T
F
F
S
F
D
V
D
S
L
K
S
S
D
M
P
G
V
S
C
PAAVG
L
S
A
Q
E
A
F
D
M
C
F
L
A
G
K
T
P
T
V
M
M
M
D
M
S
E
L
N
P
L
V
E
E
Y
R
S
P
R
V
A
V
Y
M
F
Y
H
F
-
V
L
G
F
A
T
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
49.02
34%
67
- C5 -
4MXR
2
?
A:
[224-273]
--------
F
G
L
T
G
K
N
T
F
F
S
F
D
V
D
S
L
K
S
S
D
M
P
G
V
S
C
PAAVG
L
S
A
Q
E
A
F
D
M
C
F
L
A
G
K
T
P
T
V
M
M
M
D
M
S
E
L
N
P
L
V
E
E
Y
R
S
P
R
V
A
V
Y
M
F
Y
H
F
-
V
L
G
F
A
T
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
48.72
34%
76
- C5 -
4MYN
2
?
A:
[224-273]
--------
F
G
L
T
G
K
N
T
F
F
S
F
D
V
D
S
L
K
S
S
D
M
P
G
V
S
C
PAAVG
L
S
A
Q
E
A
F
D
M
C
F
L
A
G
K
T
P
T
V
M
M
M
D
M
S
E
L
N
P
L
V
E
E
Y
R
S
P
R
V
A
V
Y
M
F
Y
H
F
-
V
L
G
F
A
T
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
46.39
29%
32
- C5 -
2Z7X
3
TLR2_HUMAN
A:
[341-427]
---------------------------------------------------------------------------------------------
L
S
E
N
L
M
V
E
E
Y
L
K
N
S
A
C
E
D
A
--
W
P
S
L
Q
T
L
I
L
R
Q
N
H
L
A
S
L
E
K
T
---
G
E
T
L
L
T
L
K
N
L
T
N
I
D
I
S
---
K
N
S
--
F
H
S
M
P
E
T
C
Q
W
P
E
K
M
K
Y
L
N
L
S
S
T
R
I
H
-
S
-
V
T
G
C
I
P
K
T
-
L
E
I
L
D
V
S
N
N
N
L
N
L
F
S
L
N
L
P
Q
L
K
E
L
Y
I
S
R
N
K
L
M
T
L
P
D
A
S
L
L
P
M
L
L
V
L
K
I
S
R
-
N
Q
L
K
----
S
V
P
D
G
I
F
-
D
R
L
T
S
L
Q
K
I
W
L
H
T
N
P
W
D
C
S
C
P
R
I
D
Y
L
S
R
W
L
N
K
N
S
Q
K
E
Q
G
S
A
K
C
S
G
S
G
K
P
V
R
S
I
I
C
-
P
--------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
44.80
30%
115
- C5 -
1VL9
8
PA21B_BOVIN
A:
[67-122]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
P
Y
T
N
N
Y
S
Y
S
C
S
N
N
E
I
T
C
S
S
E
N
------
N
A
C
E
A
-
F
I
C
N
C
D
R
N
A
A
I
C
F
S
K
V
P
Y
N
K
E
H
K
N
L
D
K
M
N
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
44.64
27%
20
- C5 -
2IOY
1
?
A:
[44-126]
----------------------------------------------------------------------------------------------------------------------------
S
K
E
L
S
N
V
E
D
L
I
Q
Q
K
V
D
V
L
L
I
N
P
V
D
S
D
A
V
V
T
A
I
K
E
A
N
S
K
N
I
P
V
I
T
I
D
R
S
A
N
G
G
D
V
V
C
H
I
A
S
D
N
-
V
-
K
G
G
E
M
A
A
E
-
F
I
A
K
A
L
K
G
K
G
N
V
V
E
L
E
G
I
P
G
A
S
A
A
R
D
R
G
K
G
F
D
E
A
I
A
K
Y
P
D
I
K
I
V
A
K
Q
A
A
D
-
F
D
R
S
----
K
G
L
S
V
M
E
-
N
I
L
Q
A
Q
P
K
I
D
A
V
F
A
Q
N
D
E
M
A
L
G
A
I
K
A
I
E
A
A
N
R
Q
G
I
I
V
V
G
F
D
G
T
E
D
A
L
K
A
I
K
E
G
K
M
-
A
A
T
I
-
A
Q
Q
P
A
L
M
G
S
L
G
V
E
M
A
D
K
Y
L
K
G
E
K
I
P
N
F
I
P
A
E
L
K
L
I
T
K
E
N
V
Q
-----------------------------------------------------------------------
10
PsiBlast_PDB
44.50
30%
112
- C5 -
2B96
7
PA21B_BOVIN
A:
[67-122]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
P
Y
T
N
N
Y
S
Y
S
C
S
N
N
E
I
T
C
S
S
E
N
------
N
A
C
E
A
-
F
I
C
N
C
D
R
N
A
A
I
C
F
S
K
V
P
Y
N
K
E
H
K
N
L
D
K
M
N
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
43.97
9%
104
- C5 -
3VEM
-
MOM1_ARATH
A:
[1732-1813]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
D
P
F
L
H
E
L
E
K
L
R
R
E
S
E
N
S
K
K
T
F
E
E
K
K
S
I
L
K
A
E
L
E
R
K
M
A
E
V
Q
A
E
F
R
R
K
F
H
E
-
V
E
A
E
-
H
N
T
R
T
T
K
I
E
K
D
K
N
L
V
I
M
N
K
L
L
A
N
A
F
L
S
-------------------------------------------------------------------------------------
11
HHSearch
43.86
44%
135
- C5 -
1G6U
-
?
A:
[10-34]
-----------------------------------------------------------------------------
Q
A
L
K
K
E
G
F
S
P
-
E
E
L
A
A
L
E
S
E
L
Q
A
L
E
K
K
L
A
A
L
K
S
K
L
--
Q
A
L
K
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
42.26
14%
62
- C5 -
3AEI
3
?
A:
[1-94]
-----------------------------
M
E
A
V
R
A
-----
Y
E
L
Q
L
E
L
Q
Q
I
R
T
L
R
Q
S
L
E
L
K
M
K
E
L
E
Y
A
E
G
I
I
T
S
L
K
S
E
R
R
I
Y
R
A
F
S
D
L
-
L
V
E
I
T
K
D
E
A
I
E
H
I
E
R
S
R
L
V
Y
K
R
E
I
--
E
K
L
K
K
R
E
K
E
I
M
E
E
L
S
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
41.89
16%
143
- C5 -
4PKY
2
TACC3_MOUSE
B:
[2-50]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
E
V
L
A
L
Q
A
S
L
R
K
A
Q
M
Q
N
H
S
L
E
M
T
L
E
Q
K
T
K
E
I
D
E
L
T
R
I
C
-
D
D
L
I
-
S
K
M
E
K
I
----------------------------------------------------------------------------------------------------------
12
HHSearch
38.49
16%
-55
- C5 -
3U0R
-
API5_HUMAN
A:
[243-293]
--------------------------------------------------------------------------
R
Q
A
V
P
L
F
S
K
N
V
H
S
-
T
-------------
R
F
V
T
Y
F
C
E
Q
V
--
L
P
N
L
G
-
T
L
T
T
-
P
--
G
L
D
I
Q
L
---
E
V
L
K
L
L
A
E
M
S
S
F
C
G
D
M
---
E
K
L
E
T
N
L
R
K
L
F
D
K
L
L
E
Y
M
P
L
P
P
K
L
Q
F
S
Y
V
E
-
C
-
L
L
Y
S
F
H
Q
L
-
G
R
K
L
P
D
F
L
T
A
K
A
E
K
L
K
D
F
K
I
R
L
Q
Y
F
A
R
G
L
Q
V
Y
I
R
Q
L
R
L
A
L
Q
G
K
T
G
E
A
L
K
T
-
E
E
N
K
----
I
K
V
V
A
L
K
-
I
T
N
N
I
N
V
L
I
K
D
L
F
P
P
S
Y
K
S
T
V
T
L
S
W
K
P
V
-------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
36.59
25%
103
- C5 -
4H13
1
PETL_MASLA
E:
[1-32]
-------------------------------------------------------------------------------------------------
M
I
L
G
A
V
F
Y
I
V
F
I
A
L
F
--
F
G
I
A
V
G
I
I
F
A
I
K
S
I
K
L
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
35.11
25%
101
* C5 *
2E74
1
PETL_MASLA
E:
[1-32]
-------------------------------------------------------------------------------------------------
M
I
L
G
A
V
F
Y
I
V
F
I
A
L
F
--
F
G
I
A
V
G
I
I
F
A
I
K
S
I
K
L
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
35.01
10%
-7
- C5 -
2KJW
-
RS6_THET8
A:
[13-73]
-----------------------------------------------------------------------------------
E
M
P
E
-
D
R
V
N
D
L
A
R
E
L
R
I
R
D
N
V
R
R
V
M
V
V
A
S
TT
P
G
R
Y
E
V
N
I
V
L
N
P
N
L
D
Q
S
Q
L
A
---
L
E
K
E
I
I
Q
R
A
L
E
N
Y
G
A
R
---
V
E
K
V
E
E
L
G
L
R
R
L
A
Y
P
I
A
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------