@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0035: (2016-03-11 )
MYTGSLYLSLISLLQNHTFQPEEKVCLFSYGSGAVGEIFSGSIVKGYDKALDKEKHLNMLESREQLSVEEYETFFNRFDNQEFDFERELTQDPYSKVYLYSIEDHIRTYKIEK
Atome Classification :
(21 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.....-..-.20-.........30........40-----.......-----..-----50......-..60........70........80---.......--..90.....------...100.-......110.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYT
G
S
L
Y
L
S
L
I
S
L
L
Q
N-HT-FQ--PEE
K
V
C
L
F
SYGSG
A
V
G
E
IFS------
G
S
I
V
K
G
Y
-----
D
K
-----AL
D
K
E
K
H
L
-
N
M
L
E
S
R
E
QL
S
V
E
E
Y
E
T
F
F
N
RFDN----QEF
D
F
E
R
--
E
LTQDPYS
K
------
V
Y
L
Y
S
I
E-D
H
I
R
T
YKIEK
1
PsiBlast_PDB
82.17
50%
-95
- C8 -
1XPK
1
?
C:
[276-384]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Y
T
G
S
L
Y
L
S
L
I
S
L
L
E
N
-
R
D
-
L
Q
--
A
G
E
T
I
G
L
F
S
Y
G
S
G
S
V
G
E
F
Y
S
------
A
T
L
V
E
G
Y
-----
K
D
-----
H
L
D
Q
A
A
H
K
-
A
L
L
N
N
R
T
E
V
S
V
D
A
Y
E
T
F
F
K
R
F
D
D
----
V
E
F
D
E
E
Q
--
D
A
V
H
E
D
R
H
I
------
F
Y
L
S
N
I
E
-
N
N
V
R
E
Y
----
46
Fugue
78.41
44%
-94
- C8 -
1X9E
2
HMGCS_ENTFL
A:
[1-383]
--------------------------------------------------MTIGID
K
I
S
F
F
V
P
P
Y
Y
I
D
M
T
A
L
A
E
A
R
NVD
P
G
K
F
H
I
GIGQD
Q
M
A
V
N
P
ISQD
I
V
T
F
A
A
N
A
A
E
A
I
LT
K
E
D
K
E
A
ID
M
V
I
V
G
T
ESSIDESKA
A
A
V
V
L
H
R
L
M
GIQPF
A
R
S
F
E
I
K
E
ACY
G
A
T
A
G
L
Q
L
A
K
N
H
V
A
L
H
PD
K
K
V
L
V
V
A
A
D
I
A
K
YGLNSGGEPT
Q
G
A
G
A
V
A
M
L
V
A
S
EPR
I
L
A
L
K
ED
N
V
M
L
T
Q
DIYD
F
W
R
P
TGHP
Y
P
M
V
D
G
P
L
S
N
E
T
Y
I
Q
S
F
A
Q
V
W
D
E
H
K
K
R
TGLDFADYD
A
L
A
F
HIPY
T
K
M
G
K
K
A
L
L
A
K
I
S
DQT
E
A
E
Q
E
R
I
L
A
R
Y
E
E
S
I
I
Y
S
R
R
V
GN
L
Y
T
G
S
L
Y
L
G
L
I
S
L
L
E
N
A
T
T
-
L
T
--
A
G
N
Q
I
G
L
F
S
Y
G
S
G
A
V
A
E
F
F
T
------
G
E
L
V
A
G
Y
-----
Q
N
-----
H
L
Q
K
E
T
H
L
-
A
L
L
D
N
R
T
E
L
S
I
A
E
Y
E
A
M
F
A
--------
E
T
L
D
T
D
I
--
D
Q
T
L
E
D
E
L
K
------
Y
S
I
S
A
I
N
-
N
T
V
R
S
Y
R
N
--
36
PsiBlast_CBE
76.76
43%
-95
- C8 -
3V4X
1
HMGCS_ENTFL
B:
[281-387]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
T
G
S
L
Y
L
G
L
I
S
L
L
E
N
-
A
T
T
L
T
--
A
G
N
Q
I
G
L
F
S
Y
G
S
G
A
V
A
E
F
F
T
------
G
E
L
V
A
G
Y
-----
Q
N
-----
H
L
Q
K
E
T
H
L
-
A
L
L
D
N
R
T
E
L
S
I
A
E
Y
E
A
M
F
----
A
----
E
T
L
D
T
D
I
--
D
Q
T
L
E
D
E
L
K
------
Y
S
I
S
A
I
N
-
N
T
V
R
S
Y
R
---
33
PsiBlast_CBE
76.13
43%
-99
- C8 -
1YSL
1
HMGCS_ENTFL
B:
[295-401]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
T
G
S
L
Y
L
G
L
I
S
L
L
E
N
-
A
T
T
L
T
--
A
G
N
Q
I
G
L
F
S
Y
G
S
G
A
V
A
E
F
F
T
------
G
E
L
V
A
G
Y
-----
Q
N
-----
H
L
Q
K
E
T
H
L
-
A
L
L
D
N
R
T
E
L
S
I
A
E
Y
E
A
M
F
----
A
----
E
T
L
D
T
D
I
--
D
Q
T
L
E
D
E
L
K
------
Y
S
I
S
A
I
N
-
N
T
V
R
S
Y
R
---
37
PsiBlast_CBE
75.67
43%
-93
- C8 -
2HDB
1
HMGCS_ENTFL
B:
[276-382]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
T
G
S
L
Y
L
G
L
I
S
L
L
E
N
-
A
T
T
L
T
--
A
G
N
Q
I
G
L
F
S
Y
G
S
G
A
V
A
E
F
F
T
------
G
E
L
V
A
G
Y
-----
Q
N
-----
H
L
Q
K
E
T
H
L
-
A
L
L
D
N
R
T
E
L
S
I
A
E
Y
E
A
M
F
----
A
----
E
T
L
D
T
D
I
--
D
Q
T
L
E
D
E
L
K
------
Y
S
I
S
A
I
N
-
N
T
V
R
S
Y
R
---
9
PsiBlast_PDB
75.49
43%
-96
- C8 -
2HDB
1
HMGCS_ENTFL
A:
[276-382]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
T
G
S
L
Y
L
G
L
I
S
L
L
E
N
-
A
T
T
L
T
--
A
G
N
Q
I
G
L
F
S
Y
G
S
G
A
V
A
E
F
F
T
------
G
E
L
V
A
G
Y
-----
Q
N
-----
H
L
Q
K
E
T
H
L
-
A
L
L
D
N
R
T
E
L
S
I
A
E
Y
E
A
M
F
----
A
----
E
T
L
D
T
D
I
--
D
Q
T
L
E
D
E
L
K
------
Y
S
I
S
A
I
N
-
N
T
V
R
S
Y
R
---
7
PsiBlast_PDB
75.12
43%
-94
- C8 -
3V4X
1
HMGCS_ENTFL
A:
[281-387]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
T
G
S
L
Y
L
G
L
I
S
L
L
E
N
-
A
T
T
L
T
--
A
G
N
Q
I
G
L
F
S
Y
G
S
G
A
V
A
E
F
F
T
------
G
E
L
V
A
G
Y
-----
Q
N
-----
H
L
Q
K
E
T
H
L
-
A
L
L
D
N
R
T
E
L
S
I
A
E
Y
E
A
M
F
----
A
----
E
T
L
D
T
D
I
--
D
Q
T
L
E
D
E
L
K
------
Y
S
I
S
A
I
N
-
N
T
V
R
S
Y
R
---
38
PsiBlast_CBE
74.83
43%
-90
- C8 -
1X9E
1
HMGCS_ENTFL
B:
[276-382]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
T
G
S
L
Y
L
G
L
I
S
L
L
E
N
-
A
T
T
L
T
--
A
G
N
Q
I
G
L
F
S
Y
G
S
G
A
V
A
E
F
F
T
------
G
E
L
V
A
G
Y
-----
Q
N
-----
H
L
Q
K
E
T
H
L
-
A
L
L
D
N
R
T
E
L
S
I
A
E
Y
E
A
M
F
----
A
----
E
T
L
D
T
D
I
--
D
Q
T
L
E
D
E
L
K
------
Y
S
I
S
A
I
N
-
N
T
V
R
S
Y
R
---
34
PsiBlast_CBE
74.53
43%
-93
- C8 -
3V4X
1
HMGCS_ENTFL
D:
[281-387]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
T
G
S
L
Y
L
G
L
I
S
L
L
E
N
-
A
T
T
L
T
--
A
G
N
Q
I
G
L
F
S
Y
G
S
G
A
V
A
E
F
F
T
------
G
E
L
V
A
G
Y
-----
Q
N
-----
H
L
Q
K
E
T
H
L
-
A
L
L
D
N
R
T
E
L
S
I
A
E
Y
E
A
M
F
----
A
----
E
T
L
D
T
D
I
--
D
Q
T
L
E
D
E
L
K
------
Y
S
I
S
A
I
N
-
N
T
V
R
S
Y
R
---
8
PsiBlast_PDB
73.88
43%
-93
- C8 -
1X9E
1
HMGCS_ENTFL
A:
[276-382]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
T
G
S
L
Y
L
G
L
I
S
L
L
E
N
-
A
T
T
L
T
--
A
G
N
Q
I
G
L
F
S
Y
G
S
G
A
V
A
E
F
F
T
------
G
E
L
V
A
G
Y
-----
Q
N
-----
H
L
Q
K
E
T
H
L
-
A
L
L
D
N
R
T
E
L
S
I
A
E
Y
E
A
M
F
----
A
----
E
T
L
D
T
D
I
--
D
Q
T
L
E
D
E
L
K
------
Y
S
I
S
A
I
N
-
N
T
V
R
S
Y
R
---
35
PsiBlast_CBE
73.75
43%
-93
- C8 -
3V4X
1
HMGCS_ENTFL
C:
[281-387]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
T
G
S
L
Y
L
G
L
I
S
L
L
E
N
-
A
T
T
L
T
--
A
G
N
Q
I
G
L
F
S
Y
G
S
G
A
V
A
E
F
F
T
------
G
E
L
V
A
G
Y
-----
Q
N
-----
H
L
Q
K
E
T
H
L
-
A
L
L
D
N
R
T
E
L
S
I
A
E
Y
E
A
M
F
----
A
----
E
T
L
D
T
D
I
--
D
Q
T
L
E
D
E
L
K
------
Y
S
I
S
A
I
N
-
N
T
V
R
S
Y
R
---
53
HHSearch
59.36
25%
-56
- C8 -
2F82
-
?
A:
[327-451]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
T
A
S
L
Y
A
A
F
A
S
L
V
H
N
-
K
H
S
D
L
--
A
G
K
R
V
V
M
F
S
Y
G
S
G
S
T
A
T
M
F
S
------
L
R
L
C
E
N
Q
-----
S
P
FS
L
S
N
I
A
S
V
M
D
V
G
-
G
K
L
K
A
R
H
E
Y
A
P
E
K
F
V
E
T
M
K
L
M
E
H
R
YGA
K
E
F
V
T
S
K
EG
I
L
D
L
L
A
P
G
T
------
Y
Y
L
K
E
V
D
S
L
Y
R
R
F
Y
G
K
K
-
17
PsiBlast_PDB
58.97
46%
-137
- C8 -
2FA0
1
?
A:
[326-366]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
T
A
S
L
Y
A
A
F
A
S
L
V
H
N
K
H
S
-
D
L
--
A
G
K
R
V
V
M
F
S
Y
G
S
G
S
T
A
T
M
F
S
-------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
58.79
50%
9
- C8 -
1XPM
1
?
B:
[278-384]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Y
T
G
S
L
Y
L
S
L
I
S
L
L
E
N
-
R
D
-
L
Q
--
A
G
E
T
I
G
L
F
S
Y
G
S
G
S
V
G
E
F
Y
S
------
A
T
L
V
E
G
Y
-----
K
D
-----
H
L
D
Q
A
A
H
K
-
A
L
L
N
N
R
T
E
V
S
V
D
A
Y
E
T
F
F
K
R
F
D
D
----
V
E
F
D
E
E
Q
--
D
A
V
H
E
D
R
H
I
------
F
Y
L
S
N
I
E
-
N
N
V
R
E
Y
----
32
PsiBlast_CBE
58.66
49%
7
- C8 -
1TXT
1
?
B:
[278-384]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Y
T
G
S
L
Y
L
S
L
I
S
L
L
E
N
-
R
D
-
L
Q
--
A
G
E
T
I
G
L
F
S
Y
G
S
G
S
V
V
E
F
Y
S
------
A
T
L
V
E
G
Y
-----
K
D
-----
H
L
D
Q
A
A
H
K
-
A
L
L
N
N
R
T
E
V
S
V
D
A
Y
E
T
F
F
K
R
F
D
D
----
V
E
F
D
E
E
Q
--
D
A
V
H
E
D
R
H
I
------
F
Y
L
S
N
I
E
-
N
N
V
R
E
Y
----
42
PsiBlast_CBE
58.37
34%
-65
- C8 -
2WYA
2
HMCS2_HUMAN
B:
[333-418]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
T
S
S
L
Y
G
C
L
A
S
L
L
S
H
-
H
S
-
A
Q
EL
A
G
S
R
I
G
A
F
S
Y
G
S
G
L
A
A
S
F
F
S
FRVSQD
A
A
P
G
S
P
L
-----
D
K
-----
L
V
S
S
T
S
D
L
P
K
R
L
A
S
R
K
C
V
S
P
E
E
F
T
E
I
M
N
Q
-------------------------------------------------
16
PsiBlast_PDB
58.20
46%
-141
- C8 -
2F9A
1
?
A:
[326-366]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
T
A
S
L
Y
A
A
F
A
S
L
V
H
N
K
H
S
-
D
L
--
A
G
K
R
V
V
M
F
S
Y
G
S
G
S
T
A
T
M
F
S
-------------------------------------------------------------------------------------------------------
47
Fugue
58.11
23%
-72
- C8 -
2F82
-
?
A:
[2-451]
AKNVGIL
A
M
D
I
Y
F
P
P
T
C
V
Q
Q
E
A
L
E
A
H
D
GASKGKYTIGLGQD
C
L
A
F
C
T
ELED
V
I
S
M
S
F
N
A
V
T
S
L
L
E
K
Y
KIDPKQIG
R
L
E
V
G
S
ETVIDKSKS
I
K
T
F
L
MQLFEKCGNTD
V
E
G
V
D
STNACY
G
G
T
A
A
L
L
N
C
V
N
W
V
E
SNSWDG
R
Y
G
L
V
I
C
T
D
S
A
V
Y
AEGPARPT
G
G
A
A
A
I
A
M
L
I
G
P
DAPIVFESKL
R
G
S
H
M
A
H
V
YDFYKPNLASE
Y
P
V
V
D
G
K
L
S
Q
T
C
Y
L
M
A
L
D
S
C
Y
K
H
L
C
N
K
F
E
K
L
EG
K
E
F
S
INDAD
Y
F
V
F
HSPY
N
K
L
V
Q
K
S
F
A
R
L
L
Y
N
D
F
L
R
NASSID
E
A
A
K
E
K
F
TPYSSLS
L
D
E
S
Y
Q
S
R
D
L
E
K
V
S
Q
Q
L
A
K
T
Y
Y
D
A
KVQPTTL
V
P
K
Q
V
GN
M
Y
T
A
S
L
Y
A
A
F
A
S
L
V
H
N
-
K
H
-
S
D
L-
A
G
K
R
V
V
M
F
S
Y
G
S
G
S
T
A
T
M
F
S
------
L
R
L
C
E
N
Q
S
PFS
L
S
N
-----
I
A
S
V
M
D
V
G
-
G
K
L
K
A
R
H
E
Y
A
P
E
K
F
V
E
T
M
K
L
M
E
H
----
R
Y
G
A
K
E
F
--
V
T
S
K
E
G
I
L
D
LLAPG
T
Y
Y
L
K
E
V
D
-
S
L
Y
R
R
F
Y
G
K
K
15
PsiBlast_PDB
57.93
46%
-142
- C8 -
2F82
-
?
A:
[327-367]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
T
A
S
L
Y
A
A
F
A
S
L
V
H
N
K
H
S
-
D
L
--
A
G
K
R
V
V
M
F
S
Y
G
S
G
S
T
A
T
M
F
S
-------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
57.85
50%
5
- C8 -
1XPM
1
?
D:
[278-384]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Y
T
G
S
L
Y
L
S
L
I
S
L
L
E
N
-
R
D
-
L
Q
--
A
G
E
T
I
G
L
F
S
Y
G
S
G
S
V
G
E
F
Y
S
------
A
T
L
V
E
G
Y
-----
K
D
-----
H
L
D
Q
A
A
H
K
-
A
L
L
N
N
R
T
E
V
S
V
D
A
Y
E
T
F
F
K
R
F
D
D
----
V
E
F
D
E
E
Q
--
D
A
V
H
E
D
R
H
I
------
F
Y
L
S
N
I
E
-
N
N
V
R
E
Y
----
55
HHSearch
52.27
39%
21
- C8 -
3SQZ
3
?
A:
[313-422]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Y
T
G
S
L
F
L
G
L
L
S
L
L
E
N
S
Q
N
-
L
V
--
A
G
D
K
I
A
L
F
S
Y
G
S
G
A
V
A
E
I
F
T
------
G
T
L
V
K
G
F
-----
K
E
-----
Q
L
Q
T
-
N
R
L
-
D
K
L
K
R
R
T
P
L
S
V
E
N
Y
E
K
I
F
F
E
E
A
Q
----
L
D
D
K
G
N
A
--
S
F
K
E
Y
Q
T
G
P
------
F
A
L
K
E
I
L
-
E
H
Q
R
I
Y
G
K
V
-