@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0043: (2016-03-11 )
MFFKQFYEDNFSQASYLIGCQRTGEAMIIDPIRDLTKYLKVADKEGFTITKAAETHIHADFASGIRDVANKLNASIYVSDEGKDEFNYKNMPKQTHFVKHQDIIYLGKIKLEVLHTPGHPPESISFLLTDEGGGSSIPMGLFSGDFIFVGDVGRPDLLEKAVNVEGSTKIGAKQMYQSIQFAATLPDYIQIWPGHGAGSPCGKALGSLPTTTLGYEKINNWAFNVKDETSFIETLTLNQPAPPHHFSQMKKINQFGMQMYQPYNVYPSSSNTQTAFDLRSKEAFHGGHMHGTINIPFNKTFINQIGWYLDYD
Atome Classification :
(20 SA)
----.........10........20.....-...30...------------.....40........50........60........70.-......-------.80-----.....-------...-----.--------90------------.....--------------.-...--100.......110.......120.......130.....-..140.......150.......160.......170.......-180...-.....190.......200.......210.......220....-...230...-....240.......250...-....260---------..---------......270.......280.......290.......300.......310----------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----M
F
F
K
Q
F
Y
EDNFSQA
S
Y
L
I
G
CQRTG
E
A
-
M
I
I
D
P
I
R
D
------------
L
T
K
Y
L
K
V
ADKEG
F
T
I
T
K
AAE
T
H
IH
A
D
F
A
S
G
I
R
D
V
A
N
KL-N
A
S
I
Y
V
-------SD------EGKDE-------FNY-----K--------N-------------MPKQT--------------
H
-
F
V
K--HQ
D
I
I
Y
L
G
K
I
K
L
E
V
L
HTPGHPPE
S
I
S
F
L
L
TDEGGGSSI-
P
M
G
LFSG
D
F
I
F
VGDVG
R
P
D
L
L
E
K
A
VNVEGSTKI
G
A
K
Q
M
Y
Q
S
I
-
Q
-
F
A
AT-LP
D
Y
I
Q
IWPGHGAG
S
P
C
G
K
A
LGSLPTTTL
G
Y
E
KIN
N
W
A
F
NVK-DET
S
F
I
E
T
L
-TLNQPAP
P
H
H
F
S
Q
M
K
K
I
N
Q
F
-
G
M
Q
MYQ----------PY---------NVYPSSSNT
Q
T
A
F
DLRSKEAFHGGH
M
H
G
T
I
NIPF
N
K
T
F
I
N
QI
G
W
Y
LDYD----------------------------------
22
PsiBlast_CBE
92.71
74%
-87
- C1 -
3R2U
3
?
C:
[25-336]
----
M
F
F
K
Q
F
Y
D
K
H
L
S
Q
A
S
Y
L
I
G
C
Q
K
T
G
E
A
-
M
I
I
D
P
I
R
D
------------
L
S
S
Y
I
R
V
A
D
E
E
G
L
T
I
T
H
A
A
E
T
H
I
H
A
D
F
A
S
G
I
R
D
V
A
I
K
L
-
N
A
N
I
Y
V
-------
S
G
------
E
S
D
D
T
-------
L
G
Y
-----
K
--------
N
-------------
M
P
N
H
T
--------------
H
-
F
V
Q
--
H
N
D
D
I
Y
V
G
N
I
K
L
K
V
L
H
T
P
G
H
T
P
E
S
I
S
F
L
L
T
D
E
G
A
G
A
Q
V
-
P
M
G
L
F
S
G
D
F
I
F
V
G
D
I
G
R
P
D
L
L
-------
G
S
S
E
I
G
A
K
Q
M
F
K
S
I
-
E
-
S
I
K
D
-
L
P
D
Y
I
Q
I
W
P
G
H
G
A
G
S
---
K
S
L
G
A
I
P
T
S
T
L
G
Y
E
K
Q
T
N
W
A
F
S
E
N
-
N
E
A
T
F
I
D
K
L
-
I
S
D
Q
P
A
P
P
H
H
F
A
Q
M
K
K
I
N
Q
F
-
G
M
N
L
Y
Q
----------
P
Y
---------
T
V
Y
P
A
T
N
T
N
R
L
T
F
D
L
R
S
K
E
A
Y
H
G
G
H
I
E
G
T
I
N
I
P
Y
D
K
N
F
I
N
Q
I
G
W
Y
L
N
Y
D
----------------------------------
1
PsiBlast_PDB
91.61
74%
-87
- C1 -
3R2U
1
?
A:
[25-336]
----
M
F
F
K
Q
F
Y
D
K
H
L
S
Q
A
S
Y
L
I
G
C
Q
K
T
G
E
A
-
M
I
I
D
P
I
R
D
------------
L
S
S
Y
I
R
V
A
D
E
E
G
L
T
I
T
H
A
A
E
T
H
I
H
A
D
F
A
S
G
I
R
D
V
A
I
K
L
-
N
A
N
I
Y
V
-------
S
G
------
E
S
D
D
T
-------
L
G
Y
-----
K
--------
N
-------------
M
P
N
H
T
--------------
H
-
F
V
Q
--
H
N
D
D
I
Y
V
G
N
I
K
L
K
V
L
H
T
P
G
H
T
P
E
S
I
S
F
L
L
T
D
E
G
A
G
A
Q
V
-
P
M
G
L
F
S
G
D
F
I
F
V
G
D
I
G
R
P
D
L
L
E
K
A
V
K
V
E
G
S
S
E
I
G
A
K
Q
M
F
K
S
I
-
E
-
S
I
K
D
-
L
P
D
Y
I
Q
I
W
P
G
H
G
A
G
S
P
C
G
K
S
L
G
A
I
P
T
S
T
L
G
Y
E
K
Q
T
N
W
A
F
S
E
N
-
N
E
A
T
F
I
D
K
L
-
I
S
D
Q
P
A
P
P
H
H
F
A
Q
M
K
K
I
N
Q
F
-
G
M
N
L
Y
Q
----------
P
Y
---------
T
V
Y
P
A
T
N
T
N
R
L
T
F
D
L
R
S
K
E
A
Y
H
G
G
H
I
E
G
T
I
N
I
P
Y
D
K
N
F
I
N
Q
I
G
W
Y
L
N
Y
D
----------------------------------
49
Fugue
91.38
74%
-87
- C1 -
3R2U
1
?
A:
[23-370]
--NA
M
F
F
K
Q
F
Y
D
K
H
L
S
Q
A
S
Y
L
I
G
C
Q
K
T
G
E
A
-
M
I
I
D
P
I
R
D
------------
L
S
S
Y
I
R
V
A
D
E
E
G
L
T
I
T
H
A
A
E
T
H
I
H
A
D
F
A
S
G
I
R
D
V
A
I
K
L
-
N
A
N
I
Y
V
-------
S
G
------
E
S
D
D
T
-------
L
G
Y
-----
K
--------
N
-------------
M
P
N
H
T
--------------
H
-
F
V
Q
--
H
N
D
D
I
Y
V
G
N
I
K
L
K
V
L
H
T
P
G
H
T
P
E
S
I
S
F
L
L
T
D
E
G
A
G
A
Q
V
-
P
M
G
L
F
S
G
D
F
I
F
V
G
D
I
G
R
P
D
L
L
E
K
A
V
K
V
E
G
S
S
E
I
G
A
K
Q
M
F
K
S
I
-
E
-
S
I
K
D
-
L
P
D
Y
I
Q
I
W
P
G
H
G
A
G
S
P
C
G
K
S
L
G
A
I
P
T
S
T
L
G
Y
E
K
Q
T
N
W
A
F
S
E
N
-
N
E
A
T
F
I
D
K
L
-
I
S
D
Q
P
A
P
P
H
H
F
A
Q
M
K
K
I
N
Q
F
-
G
M
N
L
Y
Q
----------
P
Y
---------
T
V
Y
P
A
T
N
T
N
R
L
T
F
D
L
R
S
K
E
A
Y
H
G
G
H
I
E
G
T
I
N
I
P
Y
D
K
N
F
I
N
Q
I
G
W
Y
L
N
Y
D
Q
E
I
N
L
I
G
D
Y
H
L
V
S
K
A
T
H
T
L
Q
L
I
GYDDIA
G
Y
Q
L
P
Q
23
PsiBlast_CBE
90.80
74%
-91
* C1 *
3R2U
2
?
B:
[25-336]
----
M
F
F
K
Q
F
Y
D
K
H
L
S
Q
A
S
Y
L
I
G
C
Q
K
T
G
E
A
-
M
I
I
D
P
I
R
D
------------
L
S
S
Y
I
R
V
A
D
E
E
G
L
T
I
T
H
A
A
E
T
H
I
H
A
D
F
A
S
G
I
R
D
V
A
I
K
L
-
N
A
N
I
Y
V
-------
S
G
------
E
S
D
D
T
-------
L
G
Y
-----
K
--------
N
-------------
M
P
N
H
T
--------------
H
-
F
V
Q
--
H
N
D
D
I
Y
V
G
N
I
K
L
K
V
L
H
T
P
G
H
T
P
E
S
I
S
F
L
L
T
D
E
G
A
G
A
Q
V
-
P
M
G
L
F
S
G
D
F
I
F
V
G
D
I
G
R
P
D
L
----------
S
E
I
G
A
K
Q
M
F
K
S
I
-
E
-
S
I
K
D
-
L
P
D
Y
I
Q
I
W
P
G
H
G
A
G
S
----
S
L
G
A
I
P
T
S
T
L
G
Y
E
K
Q
T
N
W
A
F
S
E
N
-
N
E
A
T
F
I
D
K
L
-
I
S
D
Q
P
A
P
P
H
H
F
A
Q
M
K
K
I
N
Q
F
-
G
M
N
L
Y
Q
----------
P
Y
---------
T
V
Y
P
A
T
N
T
N
R
L
T
F
D
L
R
S
K
E
A
Y
H
G
G
H
I
E
G
T
I
N
I
P
Y
D
K
N
F
I
N
Q
I
G
W
Y
L
N
Y
D
----------------------------------
21
PsiBlast_CBE
89.91
74%
-83
- C1 -
3R2U
2
?
D:
[25-336]
----
M
F
F
K
Q
F
Y
D
K
H
L
S
Q
A
S
Y
L
I
G
C
Q
K
T
G
E
A
-
M
I
I
D
P
I
R
D
------------
L
S
S
Y
I
R
V
A
D
E
E
G
L
T
I
T
H
A
A
E
T
H
I
H
A
D
F
A
S
G
I
R
D
V
A
I
K
L
-
N
A
N
I
Y
V
-------
S
G
------
E
S
D
D
T
-------
L
G
Y
-----
K
--------
N
-------------
M
P
N
H
T
--------------
H
-
F
V
Q
--
H
N
D
D
I
Y
V
G
N
I
K
L
K
V
L
H
T
P
G
H
T
P
E
S
I
S
F
L
L
T
D
E
G
A
G
A
Q
V
-
P
M
G
L
F
S
G
D
F
I
F
V
G
D
I
G
R
P
D
L
--------
G
S
S
E
I
G
A
K
Q
M
F
K
S
I
-
E
-
S
I
K
D
-
L
P
D
Y
I
Q
I
W
P
G
H
G
A
G
S
---
K
S
L
G
A
I
P
T
S
T
L
G
Y
E
K
Q
T
N
W
A
F
S
E
N
-
N
E
A
T
F
I
D
K
L
-
I
S
D
Q
P
A
P
P
H
H
F
A
Q
M
K
K
I
N
Q
F
-
G
M
N
L
Y
Q
----------
P
Y
---------
T
V
Y
P
A
T
N
T
N
R
L
T
F
D
L
R
S
K
E
A
Y
H
G
G
H
I
E
G
T
I
N
I
P
Y
D
K
N
F
I
N
Q
I
G
W
Y
L
N
Y
D
----------------------------------
27
HHSearch
87.13
73%
-81
- C1 -
3R2U
1
?
A:
[25-330]
----
M
F
F
K
Q
F
Y
D
K
H
L
S
Q
A
S
Y
L
I
G
C
Q
K
T
G
E
A
-
M
I
I
D
P
I
R
D
------------
L
S
S
Y
I
R
V
A
D
E
E
G
L
T
I
T
H
A
A
E
T
H
I
H
A
D
F
A
S
G
I
R
D
V
A
I
K
L
-
N
A
N
I
Y
V
-------
S
G
------
E
S
-
D
D
-------
T
L
G
-----
Y
K-------
N
-------------
M
P
N
H
T
--------------
H
-
F
V
Q
--
H
N
D
D
I
Y
V
G
N
I
K
L
K
V
L
H
T
P
G
H
T
P
E
S
I
S
F
L
L
T
D
E
G
A
G
A
Q
V
-
P
M
G
L
F
S
G
D
F
I
F
V
G
D
I
G
R
P
D
L
L
E
K
A
V
K
V
E
G
S
S
E
I
G
A
K
Q
M
F
K
S
I
-
E
-
S
I
K
D
-
L
P
D
Y
I
Q
I
W
P
G
H
G
A
G
S
P
C
G
K
S
L
G
A
I
P
T
S
T
L
G
Y
E
K
Q
T
N
W
A
F
S
E
N
-
N
E
A
T
F
I
D
K
L
-
I
S
D
Q
P
A
P
P
H
H
F
A
Q
M
K
K
I
N
Q
F
-
G
M
N
L
Y
Q
----------
P
Y
T
--------
V
Y
P
A
-
T
N
T
N
R
L
T
F
D
L
R
S
K
E
A
Y
H
G
G
H
I
E
G
T
I
N
I
P
Y
D
K
N
F
I
N
Q
I
G
----------------------------------------
2
PsiBlast_PDB
73.21
43%
-73
- C1 -
3TP9
1
?
A:
[5-326]
-----
Y
L
R
R
F
Y
D
E
G
L
A
H
A
S
Y
L
V
G
C
Q
E
T
G
E
A
-
C
V
I
D
P
A
R
D
------------
V
E
P
Y
L
L
T
A
K
R
E
G
L
R
I
V
A
A
L
E
T
H
I
H
A
D
F
V
S
G
A
R
E
M
A
D
R
A
-
G
A
A
I
C
V
-------
S
D
------
E
G
P
P
E
-------
W
K
S
-----
E
--------
Y
-------------
V
K
A
Y
P
--------------
H
R
L
L
K
--
D
G
D
E
L
H
F
G
N
V
R
I
V
V
M
H
T
P
G
H
T
P
E
H
V
S
Y
L
L
Y
D
G
K
T
S
P
D
V
-
P
M
A
L
F
S
G
D
F
V
F
V
G
D
V
G
R
P
D
L
L
E
R
V
A
G
E
S
G
S
S
E
A
L
A
R
Q
M
F
R
S
L
-
R
-
K
F
E
A
-
L
P
D
H
V
Q
V
L
P
A
H
G
A
G
S
A
C
G
K
A
L
G
A
V
P
S
S
T
V
G
Y
E
K
L
V
N
W
A
L
Q
H
K
-
D
E
D
A
F
V
Q
A
L
-
L
A
G
Q
P
E
A
P
I
Y
F
A
R
M
K
L
V
N
K
V
-
G
P
R
L
L
A
ELGAPER
V
D
L
P
P
---------
E
R
V
R
A
W
R
E
G
G
V
V
L
D
V
R
P
A
D
A
F
A
K
R
H
L
A
G
S
L
N
I
P
W
N
K
S
F
V
T
W
A
G
W
L
L
P
A
D
----------------------------------
28
HHSearch
71.85
45%
-70
- C1 -
3TP9
1
?
A:
[4-323]
----
M
Y
L
R
R
F
Y
D
E
G
L
A
H
A
S
Y
L
V
G
C
Q
E
T
G
E
A
-
C
V
I
D
P
A
R
D
------------
V
E
P
Y
L
L
T
A
K
R
E
G
L
R
I
V
A
A
L
E
T
H
I
H
A
D
F
V
S
G
A
R
E
M
A
D
R
A
-
G
A
A
I
C
V
-------
S
D
------
E
G
-
P
P
-------
E
W
K
-----
S
E-------
Y
V------------
K
A
Y
P
H
--------------
R
-
L
L
K
--
D
G
D
E
L
H
F
G
N
V
R
I
V
V
M
H
T
P
G
H
T
P
E
H
V
S
Y
L
L
Y
D
G
K
T
S
P
D
V
-
P
M
A
L
F
S
G
D
F
V
F
V
G
D
V
G
R
P
D
L
L
E
R
V
A
G
E
S
G
S
S
E
A
L
A
R
Q
M
F
R
S
L
-
R
-
K
F
E
A
-
L
P
D
H
V
Q
V
L
P
A
H
G
A
G
S
A
C
G
K
A
L
G
A
V
P
S
S
T
V
G
Y
E
K
L
V
N
W
A
L
Q
H
K
-
D
E
D
A
F
V
Q
A
L
-
L
A
G
Q
P
E
A
P
I
Y
F
A
R
M
K
L
V
N
K
V
-
G
P
R
L
L
A
E---------
L
G
APER
V
D
L
P
P
E
R
V
R
A
W
R
E
G
G
V
V
L
D
V
R
P
A
D
A
F
A
K
R
H
L
A
G
S
L
N
I
P
W
N
K
S
F
V
T
W
A
G
W
L
L
-------------------------------------
3
PsiBlast_PDB
61.86
28%
-87
- C1 -
4YSB
-
?
A:
[1-210]
----
M
I
F
R
Q
L
F
D
S
E
S
S
T
Y
T
Y
L
I
G
D
E
A
T
R
Q
A
-
V
L
I
D
P
V
L
E
Q-----------
V
D
R
D
L
Q
M
V
A
E
L
D
L
T
L
T
H
V
F
D
T
H
V
H
A
D
H
I
T
A
S
G
A
L
R
E
R
T
-
Q
A
T
V
V
G
-------
S
V
------
N
G
A
S
C
-------
A
N
V
-----
Q
--------------------------------------------
V
R
--
H
G
D
E
V
R
V
G
Q
L
V
F
Q
V
L
A
T
P
G
H
T
D
D
S
I
S
Y
L
L
G
D
R
----------
V
F
T
G
D
A
L
L
V
R
G
N
G
R
T
D
F
Q
N
G
----------
N
A
S
Q
L
Y
D
S
L
T
R
-
V
L
F
T
-
L
P
D
E
T
L
V
Y
P
G
H
D
Y
K
---
G
R
T
V
-----
T
S
I
A
E
E
K
R
H
N
P
R
V
A
G
K
-
S
R
E
E
F
I
H
I
M
E
N
L
N
L
P
R
P
----------------------------------------------------------------------------------------------------------------------------
51
Fugue
57.36
22%
-66
- C1 -
1QH5
3
GLO2_HUMAN
A:
[1-260]
--M
K
V
E
V
L
P
A
L
T
D
N
Y
M
---
Y
L
V
I
D
D
E
T
K
E
A
-
A
I
V
D
P
V
-
Q
------------
P
Q
K
V
V
D
A
A
R
K
H
G
V
K
L
T
T
V
L
T
T
H
H
H
W
D
H
A
G
G
N
E
K
L
V
K
L
E
-
S
G
L
K
V
Y
-------
G
G
------
D
-------------------
D
--------
R
-------------
I
G
A
L
T
--------------
H
-
K
I
T
--
H
L
S
T
L
Q
V
G
S
L
N
V
K
C
L
A
T
P
C
H
T
S
G
H
I
C
Y
F
V
S
K
P
G
G
S
E
---
P
P
A
V
F
T
G
D
T
L
F
V
A
G
C
G
K
F
--------
Y
E
G
T
----
A
D
E
M
C
K
A
L
L
E
-
V
L
G
R
-
L
P
P
D
T
R
V
Y
C
G
H
E
Y
T
I
N
N
L
K
F
A
R
H
V
E
P
G
N
A
A
I
R
E
K
L
A
W
A
K
E
K
Y
-
S
I
----------
G
E
P
T
V
P
S
T
L
A
E
E
F
T
Y
N
P
F
M
R
V
R
E
K
T
----------
V
Q
---------
Q
H
A
G
E
T
D
P
V
T
T
M
R
A
V
R
R
E
K
D
Q
F
--------
K
M
P
R
D
------------------------------------------------
32
HHSearch
54.57
25%
-83
- C1 -
2ZWR
9
?
A:
[1-187]
----
M
R
V
F
P
V
T
L
G
P
L
Q
E
N
A
Y
L
V
E
T
--
G
E
G
P
-
V
L
I
D
P
G
D
E
------------
P
E
K
L
L
A
L
F
Q
T
T
G
L
I
P
L
A
I
L
L
T
H
A
H
F
D
H
V
G
A
V
A
P
L
V
E
A
L
-
D
L
P
V
Y
L
-------
H
P
------
L
D
-
L
P
-------
L
Y
E
-----
G
--------
A
D
L
A
A
R
A
W
G
L
A
I
P
K
P
P
L
P
V
--------------
R
-
P
L
E
--
E
G
M
R
L
----
F
G
F
Q
V
L
H
L
P
G
H
S
P
G
H
V
A
F
Y
D
P
E
G
--------
A
Q
V
F
S
G
D
L
L
F
R
G
S
V
G
R
Y
D
L
P
----------
G
A
D
P
K
A
L
F
A
S
L
-
K
-
R
L
L
S
-
L
P
P
E
T
R
V
H
P
G
H
G
P
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
54.52
30%
-72
- C1 -
2XF4
2
?
A:
[2-195]
-----
N
Y
R
I
I
P
V
T
A
F
S
Q
N
C
S
L
I
W
C
E
Q
T
R
L
A
-
A
L
V
D
P
G
G
D
------------
A
E
K
I
K
Q
E
V
D
A
S
G
V
T
L
M
Q
I
L
L
T
H
G
H
L
D
H
V
G
A
A
S
E
L
A
Q
H
Y
-
G
V
P
V
I
G
-------
P
E
------
K
E
-
D
E
-------
F
W
L
-----
Q
G
L
P
A
Q
S
R
M
F
GLDEC
Q
-------
P
L
T
P
D
--------------
R
-
W
L
N
--
D
G
D
R
V
S
V
G
N
V
T
L
Q
V
L
H
C
P
G
H
T
P
G
H
V
V
F
F
D
E
Q
S
--------
Q
L
L
I
S
G
D
V
I
F
K
G
G
V
G
R
S
D
F
P
R
G
----------
D
H
T
Q
L
I
D
A
I
-
K
R
K
L
L
P
-
L
G
D
D
V
T
F
I
P
G
H
G
P
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
54.47
29%
-59
- C1 -
2XF4
2
?
A:
[11-205]
--------------
F
S
Q
N
C
S
L
I
W
C
E
Q
T
R
L
A
-
A
L
V
D
P
G
G
D
------------
A
E
K
I
K
Q
E
V
D
A
S
G
V
T
L
M
Q
I
L
L
T
H
G
H
L
D
H
V
G
A
A
S
E
L
A
Q
H
Y
-
G
V
P
V
-
I
-------
G
P
------
E
K
E
D
E
-------
F
W
L
-----
Q
--------
G
-------------
L
P
A
Q
S
R
M
F
GLDEC
Q
P
L
T
P
D
R
-
W
L
N
--
D
G
D
R
V
S
V
G
N
V
T
L
Q
V
L
H
C
P
G
H
T
P
G
H
V
V
F
F
--
D
E
--
Q
S
Q
L
----
L
I
S
G
D
V
I
F
K
G
G
V
G
R
S
D
F
----------
P
R
G
D
H
T
Q
L
I
D
A
I
-
K
-
R
K
L
L
P
L
G
D
D
V
T
F
I
P
G
H
G
------------
P
L
S
T
L
G
Y
E
R
L
H
N
----------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
54.26
27%
-78
- C1 -
1QH5
3
GLO2_HUMAN
A:
[1-177]
----
M
K
V
E
V
L
P
A
-
L
T
D
N
Y
M
Y
L
V
I
D
D
E
T
K
E
A
-
A
I
V
D
P
V
Q
P
-------------
Q
K
V
V
D
A
A
R
K
H
G
V
K
L
T
T
V
L
T
T
H
H
H
W
D
H
A
G
G
N
E
K
L
V
K
L
E
S
G
L
K
V
Y
G
-------
G
D
------
D
R
-
I
G
-------
A
---------------------------------
L
T
--------------
H
-
K
I
T
--
H
L
S
T
L
Q
V
G
S
L
N
V
K
C
L
A
T
P
C
H
T
S
G
H
I
C
Y
F
V
S
K
P
G
--
G
S
E
-
P
P
A
V
F
T
G
D
T
L
F
V
A
G
C
G
K
--
F
Y
E
G
----------
T
A
D
E
M
C
K
A
L
-
L
E
V
L
G
R
-
L
P
P
D
T
R
V
Y
C
G
H
E
Y
T
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
Fugue
54.07
21%
-62
- C1 -
4EFZ
7
Y2304_BURP1
A:
[1-298]
GPGS
M
T
V
E
G
F
F
D
P
A
T
C
T
I
S
Y
L
L
F
D
S
G
S
G
E
C
-
A
L
I
D
S
V
L
D
YDPKSGRTRT
A
S
A
D
Q
L
I
A
R
V
A
A
L
G
A
R
V
R
W
L
L
E
T
H
V
H
A
D
H
L
S
A
A
P
Y
L
K
T
R
V
-
G
G
E
I
A
I
G
RH
V
T
R
V
Q
D
------
V
F
G
K
L
-------
F
N
A
GPAFA
H
--------
D
-------------
G
S
Q
F
D
--------------
R
-
L
L
D
--
D
G
D
T
L
A
L
G
A
L
S
I
R
A
M
H
T
P
G
H
T
P
A
C
M
T
Y
V
V
T
E
A
H
A
A
H
D
A
R
D
A
A
A
F
V
G
D
T
L
F
M
P
D
Y
G
T
A
R
-----
C
D
F
P
G
G
D
---
A
R
S
L
Y
R
S
I
-
R
-
K
V
L
S
-
L
P
P
A
T
R
L
Y
M
C
H
D
Y
Q
P
A
-----
I
Q
Y
A
S
T
V
A
D
E
L
R
E
N
V
H
I
R
E
G
V
-
T
E
D
D
F
V
A
M
R
-
T
A
R
D
A
T
L
D
-----
M
P
V
L
M
L
P
-
S
V
Q
V
N
M
----------
R
A
---------
G
R
L
P
E
P
E
D
N
G
V
R
Y
----------------
L
K
I
P
L
D
A
I
----------------------------------------------
12
PsiBlast_PDB
52.40
25%
-82
- C1 -
1XM8
3
GLO2N_ARATH
A:
[10-169]
-----------
K
D
N
Y
A
---
Y
I
L
H
D
E
D
T
G
T
V
-
G
V
V
D
P
-
S
E
------------
A
E
P
I
I
D
S
L
K
R
S
G
R
N
L
T
Y
I
L
N
T
H
H
H
Y
D
H
T
G
G
N
L
E
L
K
D
R
Y
-
G
A
K
V
I
G
-------
S
A
------
M
D
K
D
R
--------------------------------------
I
P
G
I
D
--------------
M
-
A
L
K
--
D
G
D
K
W
M
F
A
G
H
E
V
H
V
M
D
T
P
G
H
T
K
G
H
I
S
L
Y
F
P
----
G
S
R
----
A
I
F
T
G
D
T
M
F
S
L
S
C
G
K
L
--------
F
E
G
T
----
P
K
Q
M
L
A
S
L
-
Q
-
K
I
T
S
-
L
P
D
D
T
S
I
Y
C
G
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
51.85
25%
-80
- C1 -
2Q42
3
GLO2N_ARATH
A:
[10-169]
-----------
K
D
N
Y
A
---
Y
I
L
H
D
E
D
T
G
T
V
-
G
V
V
D
P
-
S
E
------------
A
E
P
I
I
D
S
L
K
R
S
G
R
N
L
T
Y
I
L
N
T
H
H
H
Y
D
H
T
G
G
N
L
E
L
K
D
R
Y
-
G
A
K
V
I
G
-------
S
A
------
M
D
K
D
R
--------------------------------------
I
P
G
I
D
--------------
M
-
A
L
K
--
D
G
D
K
W
M
F
A
G
H
E
V
H
V
M
D
T
P
G
H
T
K
G
H
I
S
L
Y
F
P
----
G
S
R
----
A
I
F
T
G
D
T
M
F
S
L
S
C
G
K
L
--------
F
E
G
T
----
P
K
Q
M
L
A
S
L
-
Q
-
K
I
T
S
-
L
P
D
D
T
S
I
Y
C
G
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
51.57
22%
-63
- C1 -
4YSK
1
?
A:
[12-247]
---------
F
Y
D
E
A
T
S
T
I
S
Y
L
V
M
D
R
E
T
R
Q
C
-
A
L
I
D
S
V
L
D
Y
D
PKSGRTCS
A
S
A
D
R
L
V
E
R
V
N
E
L
N
A
S
V
R
W
V
L
E
T
H
V
H
A
D
H
L
S
A
A
A
Y
L
K
E
K
L
-
G
G
H
T
A
I
-------
G
A
------
H
I
T
Q
V
Q
K
V
F
G
A
L
F
N
A
EPGFA
R
--------
D
-------------
G
S
Q
F
D
--------------
V
-
L
L
E
--
D
E
E
G
F
R
I
G
N
L
Q
A
R
A
L
H
T
P
G
H
T
P
A
C
M
S
F
M
I
E
D
A
G
------
E
I
A
V
F
V
G
D
T
L
F
M
P
D
Y
G
-----
T
A
R
C
D
F
P
G
A
---
D
A
R
T
L
Y
R
S
I
-
R
-
R
L
L
A
-
F
P
D
Q
T
R
L
F
M
C
H
D
Y
-
L
P
G
G
R
D
M
Q
Y
V
--
T
T
V
A
E
Q
R
A
S
N
I
H
I
H
Q
G
I
D
E
D
S
F
V
---------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
51.33
27%
-70
- C1 -
2ZWR
8
?
A:
[11-197]
--------------
L
Q
E
N
A
Y
L
V
---
E
T
G
E
G
P
V
L
I
D
P
G
D
E
------------
P
E
K
L
L
A
L
F
Q
T
T
G
L
I
P
L
A
I
L
L
T
H
A
H
F
D
H
V
G
A
V
A
P
L
V
E
A
L
-
D
L
P
V
Y
L
-------
H
P
LD
L
P
L
Y
E
G
A
D
L
-------
A
A
R
-----
A
W
G
L
-----
A
-------------
I
P
K
P
P
--------------
L
-
P
V
R
P
L
E
E
G
M
R
L
F
G
---
F
Q
V
L
H
L
P
G
H
S
P
G
H
V
A
F
--
Y
D
P
E
G
A
Q
------
V
F
S
G
D
L
L
F
R
G
S
V
G
R
Y
D
L
----------
P
G
A
D
P
K
A
L
F
A
S
L
-
K
-
R
L
L
S
-
L
P
P
E
T
R
V
H
P
G
H
G
P
G
------------
T
T
L
G
L
E
A
R
T
N
----------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
50.32
27%
-71
- C1 -
1QH5
3
GLO2_HUMAN
A:
[15-173]
-------------------
Y
L
V
I
D
D
E
T
K
E
A
-
A
I
V
D
P
V
Q
P
-------------
Q
K
V
V
D
A
A
R
K
H
G
V
K
L
T
T
V
L
T
T
H
H
H
W
D
H
A
G
G
N
E
K
L
V
-
K
L
-
E
S
G
L
K
V
-------
Y
--------
G
G
D
D
------------------------
R
-------------
I
G
A
L
T
--------------
H
-
K
I
T
--
H
L
S
T
L
Q
V
G
S
L
N
V
K
C
L
A
T
P
C
H
T
S
G
H
I
C
Y
F
V
S
K
P
G
G
--
S
E
-
P
P
A
V
F
T
G
D
T
L
F
V
A
G
C
G
K
--------
F
Y
E
G
T
A
D
E
M
C
K
A
L
---
L
-
E
-
V
L
G
R
-
L
P
P
D
T
R
V
Y
C
G
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------