@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0102: (2016-03-12 )
MYYSYGNYEAFARPKKPENVENKSAYLIGSGLASLAAACFLIRDGQMEGSKIHILEELPKAGGSLDGENMPLKGYVVRGGREMENHFECLWDLFRSIPSLEIDNASVLDEFYWLNKEDPNYSRCRVIEKQGQRLVTDGDFTLTKTAIKEILDLCLTNEEDLDDVKITDVFSDDFFNSNFWIYWKTMFAFEPWHSAMEMRRYLMRFVHHIGGLADFSALKFTKYNQYESLVLPMVEYLKSHGVQFEYDVKVEDIKVDVTTSQKIAREILIHRHGKAESIKLTVDDLVFVTNGSITESSTYGDNDTPAPPTDELGGSWTLWKNLARQSPEFGNPDKFCQNIPKKSWFVSATSTTNNKEIIDTIESICKRDPLAGKTVTGGIITINDSAWQMSFTINRQQQFKDQPENEISTWIYALYSDVNGDYIKKPITECSGNEICQEWLYHLGVSTDKIEDLAKHVSNTIPVYMPYITSYFMTRAIGDRPLVVPHQSQNLSFIGNFAETERDTVFTTEYSVRTAMEAVYQLLNIDRGIPEVINSTFDLRVLMDAVYELNDHQDLREITKDSKMQKLALAGFLKKIKGTYIETLLKEHKLL
Atome Classification :
(20 SA)
--------------.........10........20....-------------------------....30........40......--.--.--50........60-------........70........80----.....---.----.--..90........100...-....-110.......120.......130....-..-..140.......---150...-..---..160.......170.....----..180...----.-...190........200.......210-........220.......230.......240........250.......260.......270.--......280.......290.......300...--------..------..310.-..-----....320..--.....330........340.....----..350.......360.......---370.......380.....---------..390.-.---.....400........410.......420.......430.......440.......450..--....-.460-........470.......480.......490.......500........510....-...520.......530.......540.......550.......560..-.....570....--...580.......590---------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------
M
Y
Y
SYGN
Y
E
AFARPKKPENVENK
S
A
-------------------------
Y
L
IGS
G
L
A
S
L
A
A
A
C
F
L
I
RDGQM--E--G--
S
K
I
H
I
L
E
E
L
P
KA-------GGSLDGENMP
L
K
G
Y
V
VRGG-----
R
E
M
E
N
---
H
----
F
--
E
C
L
W
D
L
F
R
SIPSLEID
N
A
-
S
V
L
D
-
E
F
YWLNKEDP
N
Y
S
R
C
R
V
I
E
KQG-
Q
R
L
V-TD-GDFT
L
T
K
T
A
I
K
E
---
I
L
D
L
CL-TN---EEDLDD
V
K
I
T
D
V
FSDDFFNS----
N
F
W
I
Y
W
K
T
----
M
-
F
AF
E
P
-
W
H
S
A
M
E
M
R
R
Y
L
M
R
F
V
H
H
IGG--LAD
F
S
A
L
K
F
TKY
N
Q
Y
E
S
L
V
L
P
M
V
E
Y
L
K
SH-G
V
Q
F
E
Y
D
V
K
V
E
D
I
K
V
D
VT
T
S
Q
K
I
A
R
E
I
L
I
HRHG--KA
E
S
I
K
L
T
V
D
D
L
V
F
VTNGSITESSTYGDNDTP--------AP------PTDELG-G
S
-----
W
T
L
W
K
N
L
A
R--QSPEFG
N
-
P
D
K
F
C
Q
NIPKK
S
W
F
V
S
----
A
TSTTN
N
K
E
I
I
D
T
I
E
S
I
C
KRDP---LAGKTVTG
G
I
I
T
INDS
A
W
---------
Q
M
S
F
T
I-
N
---
R
Q
Q
QFKD-QPE
N
E
I
S
T
W
I
Y
A
L
Y
SDVN
G
D
Y
I
K
K
P
I
T
ECS
G
N
E
I
C
Q
E
W
L
Y
HLGV
S
T
D
K
I
E
D
L
A
--
K
H
V
S
-NTI--P
V
Y
M
P
Y
I
T
S
Y
F
M
T
RAIGDR
P
L
VVPHQSQN
L
S
F
I
GNFAETE-R
D
T
V
F
T
T
E
Y
S
V
R
T
A
M
-
E
A
V
Y
Q
L
L
N
IDRG
I
P
E
V
I
N
STF
D
L
R
V
L
M
D
A
V
YELN
D
H
Q
D
L
R
E
I
T
K
D
S
K
M
-
Q
K
L
A
L
A
G
F
L
K
K
I
--
K
G
T
Y
I
E
T
L
L
K
EHKLL----------
36
Fugue
99.41
61%
-87
- C2 -
4IA6
21
?
A:
[1-591]
--------------
M
Y
Y
S
N
G
N
Y
E
A
F
A
D
P
K
K
P
A
G
V
D
K
K
S
A
-------------------------
Y
I
I
G
S
G
L
A
G
L
S
T
A
V
F
L
V
R
D
A
Q
M
--
K
--
G
--
E
N
I
H
I
L
E
E
L
P
-------------------
V
A
G
F
V
V
R
G
G
-----
R
E
M
E
N
---
H
----
F
--
E
C
L
W
D
M
Y
R
S
I
P
S
L
E
V
P
G
A
-
S
Y
L
D
-
E
Y
Y
W
L
D
K
E
D
P
N
S
S
N
C
R
L
I
Y
N
R
G
-
D
R
L
P
-
S
D
-
G
Q
Y
G
L
G
K
C
A
-
N
E
---
I
V
K
L
I
M
-
T
P
---
E
K
E
I
E
G
Q
T
I
E
E
F
F
S
D
E
F
F
K
T
----
N
F
W
T
Y
W
S
T
----
M
-
F
A
F
E
K
-
W
H
S
L
A
E
M
R
R
Y
A
M
R
F
I
H
H
I
D
G
--
L
P
D
F
T
A
L
K
F
N
K
Y
N
Q
Y
E
S
M
V
K
P
L
L
A
Y
L
K
D
H
-
G
V
Q
F
E
Y
D
C
H
V
K
N
V
E
V
D
H
E
G
D
S
K
I
A
K
K
I
V
M
T
Q
N
G
--
K
D
K
E
I
D
L
T
H
N
D
I
V
F
V
T
N
G
S
I
T
E
S
S
T
Y
G
D
Q
N
T
P
--------
A
P
------
I
T
N
A
K
G
-
D
S
-----
W
K
L
W
E
N
L
A
K
--
Q
D
P
A
F
G
H
-
P
D
V
F
C
E
N
L
P
E
R
S
W
F
V
S
----
A
T
A
T
L
E
N
K
K
L
A
P
Y
F
E
R
L
T
K
R
S
L
---
Y
D
G
K
V
N
T
G
G
I
I
T
I
V
D
S
N
W
---------
E
L
S
F
T
I
-
H
---
R
Q
P
H
F
K
S
-
Q
N
P
D
Q
I
V
V
W
I
Y
A
L
Y
S
D
T
E
G
N
Y
I
K
K
R
I
V
D
C
T
G
K
E
I
A
E
E
L
L
Y
H
L
G
V
P
E
S
Q
I
S
E
L
A
S-
E
E
N
M
-
N
T
V
--
P
V
Y
M
P
Y
I
T
S
Y
F
M
P
R
R
D
G
D
R
P
D
V
V
P
E
G
S
I
N
L
A
F
I
G
N
F
A
E
S
P
T
R
D
T
V
F
T
T
E
Y
S
V
R
T
A
M
-
E
A
V
Y
T
L
L
N
V
D
R
G
V
P
E
V
F
D
S
I
Y
D
I
R
Q
L
L
R
A
M
Y
Y
M
S
D
K
K
K
L
A
D
Q
D
M
-
P
L
P
-
E
K
L
A
V
K
T
G
M
R
K
I
--
K
K
T
W
V
E
E
L
L
K
E
A
N
L
V
----------
1
PsiBlast_PDB
99.22
60%
-88
- C2 -
4IA6
21
?
A:
[1-591]
--------------
M
Y
Y
S
N
G
N
Y
E
A
F
A
D
P
K
K
P
A
G
V
D
K
K
S
A
-------------------------
Y
I
I
G
S
G
L
A
G
L
S
T
A
V
F
L
V
R
D
A
Q
M
--
K
--
G
--
E
N
I
H
I
L
E
E
L
P
V
A
-------
G
------------
F
V
V
R
G
G
-----
R
E
M
E
N
---
H
----
F
--
E
C
L
W
D
M
Y
R
S
I
P
S
L
E
V
P
G
A
-
S
Y
L
D
-
E
Y
Y
W
L
D
K
E
D
P
N
S
S
N
C
R
L
I
Y
N
R
G
-
D
R
L
P
-
S
D
-
G
Q
Y
G
L
G
K
C
A
-
N
E
---
I
V
K
L
I
M
-
T
P
---
E
K
E
I
E
G
Q
T
I
E
E
F
F
S
D
E
F
F
K
T
----
N
F
W
T
Y
W
S
T
----
M
-
F
A
F
E
K
-
W
H
S
L
A
E
M
R
R
Y
A
M
R
F
I
H
H
I
D
G
--
L
P
D
F
T
A
L
K
F
N
K
Y
N
Q
Y
E
S
M
V
K
P
L
L
A
Y
L
K
D
H
-
G
V
Q
F
E
Y
D
C
H
V
K
N
V
E
V
D
H
E
G
D
S
K
I
A
K
K
I
V
M
T
Q
N
G
--
K
D
K
E
I
D
L
T
H
N
D
I
V
F
V
T
N
G
S
I
T
E
S
S
T
Y
G
D
Q
N
T
P
--------
A
P
------
I
T
N
A
K
G
-
D
S
-----
W
K
L
W
E
N
L
A
K
--
Q
D
P
A
F
G
H
-
P
D
V
F
C
E
N
L
P
E
R
S
W
F
V
S
----
A
T
A
T
L
E
N
K
K
L
A
P
Y
F
E
R
L
T
K
R
S
L
---
Y
D
G
K
V
N
T
G
G
I
I
T
I
V
D
S
N
W
---------
E
L
S
F
T
I
-
H
---
R
Q
P
H
F
K
S
-
Q
N
P
D
Q
I
V
V
W
I
Y
A
L
Y
S
D
T
E
G
N
Y
I
K
K
R
I
V
D
C
T
G
K
E
I
A
E
E
L
L
Y
H
L
G
V
P
E
S
Q
I
S
E
L
A
--
S
E
E
N
M
N
T
V
--
P
V
Y
M
P
Y
I
T
S
Y
F
M
P
R
R
D
G
D
R
P
D
V
V
P
E
G
S
I
N
L
A
F
I
G
N
F
A
E
S
P
T
R
D
T
V
F
T
T
E
Y
S
V
R
T
A
M
-
E
A
V
Y
T
L
L
N
V
D
R
G
V
P
E
V
F
D
S
I
Y
D
I
R
Q
L
L
R
A
M
Y
Y
M
S
D
K
K
K
L
A
D
--
Q
D
M
P
L
P
E
K
L
A
V
K
T
G
M
R
K
I
--
K
K
T
W
V
E
E
L
L
K
E
A
N
L
V
----------
2
PsiBlast_PDB
98.11
59%
-89
- C2 -
4IA5
6
?
A:
[2-591]
---------------
Y
Y
S
N
G
N
Y
E
A
F
A
D
P
K
K
P
A
G
V
D
K
K
S
A
-------------------------
Y
I
I
G
S
G
L
A
G
L
S
T
A
V
F
L
V
R
D
A
Q
M
--
K
--
G
--
E
N
I
H
I
L
E
E
L
P
V
---------------------
F
V
V
R
G
G
-----
R
E
M
E
N
---
H
----
F
--
E
C
L
W
D
M
Y
R
S
I
P
S
L
E
V
P
G
A
-
S
Y
L
D
-
E
Y
Y
W
L
D
K
E
D
P
N
S
S
N
C
R
L
I
Y
N
R
G
-
D
R
L
P
-
S
D
-
G
Q
Y
G
L
G
K
C
A
-
N
E
---
I
V
K
L
I
M
-
T
P
---
E
K
E
I
E
G
Q
T
I
E
E
F
F
S
D
E
F
F
K
T
----
N
F
W
T
Y
W
S
T
----
M
-
F
A
F
E
K
-
W
H
S
L
A
E
M
R
R
Y
A
M
R
F
I
H
H
I
D
G
--
L
P
D
F
T
A
L
K
F
N
K
Y
N
Q
Y
E
S
M
V
K
P
L
L
A
Y
L
K
D
H
-
G
V
Q
F
E
Y
D
C
H
V
K
N
V
E
V
D
H
E
G
D
S
K
I
A
K
K
I
V
M
T
Q
N
G
--
K
D
K
E
I
D
L
T
H
N
D
I
V
F
V
T
N
G
S
I
T
E
S
S
T
Y
G
D
Q
N
T
P
--------
A
P
------
I
T
N
A
K
G
-
D
S
-----
W
K
L
W
E
N
L
A
K
--
Q
D
P
A
F
G
H
-
P
D
V
F
C
E
N
L
P
E
R
S
W
F
V
S
----
A
T
A
T
L
E
N
K
K
L
A
P
Y
F
E
R
L
T
K
R
S
L
---
Y
D
G
K
V
N
T
G
G
I
I
T
I
V
D
S
N
W
---------
E
L
S
F
T
I
-
H
---
R
Q
P
H
F
K
S
-
Q
N
P
D
Q
I
V
V
W
I
Y
A
L
Y
S
D
T
E
G
N
Y
I
K
K
R
I
V
D
C
T
G
K
E
I
A
E
E
L
L
Y
H
L
G
V
P
E
S
Q
I
S
E
L
A
--
S
E
E
N
M
N
T
V
--
P
V
Y
M
P
Y
I
T
S
Y
F
M
P
R
R
D
G
D
R
P
D
V
V
P
E
G
S
I
N
L
A
F
I
G
N
F
A
E
S
P
T
R
D
T
V
F
T
T
E
Y
S
V
R
T
A
M
-
E
A
V
Y
T
L
L
N
V
D
R
G
V
P
E
V
F
D
S
I
Y
D
I
R
Q
L
L
R
A
M
Y
Y
M
S
D
K
K
K
L
A
D
--
Q
D
M
P
L
P
E
K
L
A
V
K
T
G
M
R
K
I
--
K
K
T
W
V
E
E
L
L
K
E
A
N
L
V
----------
10
PsiBlast_CBE
97.34
60%
-89
- C2 -
4IA6
15
?
B:
[1-591]
--------------
M
Y
Y
S
N
G
N
Y
E
A
F
A
D
P
K
K
P
A
G
V
D
K
K
S
A
-------------------------
Y
I
I
G
S
G
L
A
G
L
S
T
A
V
F
L
V
R
D
A
Q
M
--
K
--
G
--
E
N
I
H
I
L
E
E
L
P
-----------------------
V
V
R
G
G
-----
R
E
M
E
N
---
H
----
F
--
E
C
L
W
D
M
Y
R
S
I
P
S
L
E
V
P
G
A
-
S
Y
L
D
-
E
Y
Y
W
L
D
K
E
D
P
N
S
S
N
C
R
L
I
Y
N
R
G
-
D
R
L
P
-
S
D
-
G
Q
Y
G
L
G
K
C
A
-
N
E
---
I
V
K
L
I
M
-
T
P
---
E
K
E
I
E
G
Q
T
I
E
E
F
F
S
D
E
F
F
K
T
----
N
F
W
T
Y
W
S
T
----
M
-
F
A
F
E
K
-
W
H
S
L
A
E
M
R
R
Y
A
M
R
F
I
H
H
I
D
G
--
L
P
D
F
T
A
L
K
F
N
K
Y
N
Q
Y
E
S
M
V
K
P
L
L
A
Y
L
K
D
H
-
G
V
Q
F
E
Y
D
C
H
V
K
N
V
E
V
D
H
E
G
D
S
K
I
A
K
K
I
V
M
T
Q
N
G
--
K
D
K
E
I
D
L
T
H
N
D
I
V
F
V
T
N
G
S
I
T
E
S
S
T
Y
G
D
Q
N
T
P
--------
A
P
------
I
T
N
A
K
G
-
D
S
-----
W
K
L
W
E
N
L
A
K
--
Q
D
P
A
F
G
H
-
P
D
V
F
C
E
N
L
P
E
R
S
W
F
V
S
----
A
T
A
T
L
E
N
K
K
L
A
P
Y
F
E
R
L
T
K
R
S
L
---
Y
D
G
K
V
N
T
G
G
I
I
T
I
V
D
S
N
W
---------
E
L
S
F
T
I
-
H
---
R
Q
P
H
F
K
S
-
Q
N
P
D
Q
I
V
V
W
I
Y
A
L
Y
S
D
T
E
G
N
Y
I
K
K
R
I
V
D
C
T
G
K
E
I
A
E
E
L
L
Y
H
L
G
V
P
E
S
Q
I
S
E
L
A
--
S
E
E
N
M
N
T
V
--
P
V
Y
M
P
Y
I
T
S
Y
F
M
P
R
R
D
G
D
R
P
D
V
V
P
E
G
S
I
N
L
A
F
I
G
N
F
A
E
S
P
T
R
D
T
V
F
T
T
E
Y
S
V
R
T
A
M
-
E
A
V
Y
T
L
L
N
V
D
R
G
V
P
E
V
F
D
S
I
Y
D
I
R
Q
L
L
R
A
M
Y
Y
M
S
D
K
K
K
--
D
--
Q
---------------
K
I
--
K
K
T
W
V
E
E
L
L
K
E
A
N
L
V
----------
3
PsiBlast_PDB
89.71
45%
-80
* C2 *
4UIR
3
OLHYD_ELIME
A:
[58-620]
-------------------------------
Q
S
Y
D
N
S
K
I
-------------------------
Y
I
I
G
S
G
I
A
G
M
S
A
A
Y
Y
F
I
R
D
G
H
V
--
P
--
A
--
K
N
I
T
F
L
E
Q
L
H
I
D
-------
G
G
S
L
D
G
A
G
N
P
T
D
G
Y
I
I
R
G
G
-----
R
E
M
D
M
---
T
----
Y
--
E
N
L
W
D
M
F
Q
D
I
P
A
L
E
M
P
A
P
Y
S
V
L
D
-
E
Y
R
L
I
N
D
N
D
S
N
Y
S
K
A
R
L
I
N
N
K
G
-
E
--
I
-
K
D
F
S
K
F
G
L
N
K
M
D
Q
L
A
---
I
I
R
L
L
L
-
K
N
---
K
E
E
L
D
D
L
T
I
E
D
Y
F
S
E
S
F
L
K
S
----
N
F
W
T
F
W
R
T
----
M
-
F
A
F
E
N
-
W
H
S
L
L
E
L
K
L
Y
M
H
R
F
L
H
A
I
D
G
--
L
N
D
L
S
S
L
V
F
P
K
Y
N
Q
Y
D
T
F
V
T
P
L
R
K
F
L
Q
E
K
-
G
V
N
I
H
L
N
T
L
V
K
D
L
D
I
H
I
N
T
E
G
K
V
V
E
G
I
I
T
E
Q
D
G
--
K
E
V
K
I
P
V
G
K
N
D
Y
V
I
V
T
T
G
S
M
T
E
D
T
F
Y
G
N
N
K
T
---------
A
P
IIGIDN
S
T
S
G
Q
S
-
A
G
-----
W
K
L
W
K
N
L
A
A
--
K
S
E
I
F
G
K
-
P
E
K
F
C
S
N
I
E
K
S
A
W
-
E
S
----
A
T
L
T
C
K
P
S
A
L
I
D
K
L
K
E
Y
S
V
N
D
P
---
Y
S
G
K
T
V
T
G
G
I
I
T
I
T
D
S
N
W
---------
L
M
S
F
T
C
-
N
---
R
Q
P
H
F
P
E
-
Q
P
D
D
V
L
V
L
W
V
Y
A
L
F
M
D
K
E
G
N
Y
I
K
K
T
M
L
E
C
T
G
D
E
I
L
A
E
L
C
Y
H
L
G
I
E
-
D
Q
L
E
N
V
Q
--
K
----
N
T
I
V
R
T
A
F
M
P
Y
I
T
S
M
F
M
P
R
A
K
G
D
R
P
R
V
V
P
E
G
C
K
N
L
G
L
V
G
Q
F
V
E
T
N
-
N
D
V
V
F
T
M
E
S
S
V
R
T
A
R
-
I
A
V
Y
K
L
L
N
L
N
K
Q
V
P
D
I
N
P
L
Q
Y
D
I
R
H
L
L
K
A
A
K
T
L
N
D
D
-------------
K
P
F
V
G
E
G
L
L
R
K
V
L-
K
G
T
Y
F
E
H
V
L
----------------
11
PsiBlast_CBE
89.49
45%
-80
- C2 -
4UIR
2
OLHYD_ELIME
B:
[58-619]
-------------------------------
Q
S
Y
D
N
S
K
I
-------------------------
Y
I
I
G
S
G
I
A
G
M
S
A
A
Y
Y
F
I
R
D
G
H
V
--
P
--
A
--
K
N
I
T
F
L
E
Q
L
H
I
D
-------
G
G
S
L
D
G
A
G
N
P
T
D
G
Y
I
I
R
--------
E
M
D
M
---
T
----
Y
--
E
N
L
W
D
M
F
Q
D
I
P
A
L
E
M
P
A
P
Y
S
V
L
D
-
E
Y
R
L
I
N
D
N
D
S
N
Y
S
K
A
R
L
I
N
N
K
G
-
E
--
I
-
K
D
F
S
K
F
G
L
N
K
M
D
Q
L
A
---
I
I
R
L
L
L
-
K
N
---
K
E
E
L
D
D
L
T
I
E
D
Y
F
S
E
S
F
L
K
S
----
N
F
W
T
F
W
R
T
----
M
-
F
A
F
E
N
-
W
H
S
L
L
E
L
K
L
Y
M
H
R
F
L
H
A
I
D
G
--
L
N
D
L
S
S
L
V
F
P
K
Y
N
Q
Y
D
T
F
V
T
P
L
R
K
F
L
Q
E
K
-
G
V
N
I
H
L
N
T
L
V
K
D
L
D
I
H
I
N
T
E
G
K
V
V
E
G
I
I
T
E
Q
D
G
--
K
E
V
K
I
P
V
G
K
N
D
Y
V
I
V
T
T
G
S
M
T
E
D
T
F
Y
G
N
N
K
T
---------
A
P
IIGIDN
S
T
S
G
Q
S
-
A
G
-----
W
K
L
W
K
N
L
A
A
--
K
S
E
I
F
G
K
-
P
E
K
F
C
S
N
I
E
K
S
A
W
-
E
S
----
A
T
L
T
C
K
P
S
A
L
I
D
K
L
K
E
Y
S
V
N
D
P
---
Y
S
G
K
T
V
T
G
G
I
I
T
I
T
D
S
N
W
---------
L
M
S
F
T
C
-
N
---
R
Q
P
H
F
P
E
-
Q
P
D
D
V
L
V
L
W
V
Y
A
L
F
M
D
K
E
G
N
Y
I
K
K
T
M
L
E
C
T
G
D
E
I
L
A
E
L
C
Y
H
L
G
I
E
-
D
Q
L
E
N
V
Q
--
K
----
N
T
I
V
R
T
A
F
M
P
Y
I
T
S
M
F
M
P
R
A
K
G
D
R
P
R
V
V
P
E
G
C
K
N
L
G
L
V
G
Q
F
V
E
T
N
-
N
D
V
V
F
T
M
E
S
S
V
R
T
A
R
-
I
A
V
Y
K
L
L
N
L
N
K
Q
V
P
D
I
N
P
L
Q
Y
D
I
R
H
L
L
K
A
A
K
T
L
N
D
D
-------------
K
P
F
V
G
E
G
L
L
R
K
V
L-
K
G
T
Y
F
E
H
V
L
----------------
37
Fugue
88.60
44%
-74
- C2 -
4UIR
3
OLHYD_ELIME
A:
[2-646]
NPITSKF
D
K
V
L
N
A
S
S
E
Y
G
H
V
N
H
E
P
D
S
S
K
E
Q
Q
R
N
T
P
Q
K
S
M
PFSDQIGNYQR
N
K
G
I
P
VQSYDN
S
K
I
Y
I
I
G
S
G
I
A
G
M
S
A
A
Y
Y
F
I
R
D
G
H
V
--
P
--
A
--
K
N
I
T
F
L
E
Q
L
H
I
D
-------
G
G
S
L
D
G
A
G
N
P
T
D
G
Y
I
I
R
G
G
-----
R
E
M
D
M
---
T
----
Y
--
E
N
L
W
D
M
F
Q
D
I
P
A
L
E
M
P
A
P
Y
S
V
L
D
-
E
Y
R
L
I
N
D
N
D
S
N
Y
S
K
A
R
L
I
N
N
K
G
--
E
I
K
-
D
F
-
S
K
F
G
L
N
K
M
D
Q
L
A
---
I
I
R
L
L
L
-
K
N
---
K
E
E
L
D
D
L
T
I
E
D
Y
F
S
E
S
F
L
K
S
----
N
F
W
T
F
W
R
T
----
M
-
F
A
F
E
N
-
W
H
S
L
L
E
L
K
L
Y
M
H
R
F
L
H
A
I
D
G
--
L
N
D
L
S
S
L
V
F
P
K
Y
N
Q
Y
D
T
F
V
T
P
L
R
K
F
L
Q
E
K
-
G
V
N
I
H
L
N
T
L
V
K
D
L
D
I
H
I
N
T
E
G
K
V
V
E
G
I
I
T
E
Q
D
G
--
K
E
V
K
I
P
V
G
K
N
D
Y
V
I
V
T
T
G
S
M
T
E
D
T
F
Y
G
N
N
K
T
A
--------
P
I
------
I
G
I
D
N
S
-
T
S
GQSA
G
W
K
L
W
K
N
L
A
A
--
K
S
E
I
F
G
K
-
P
E
K
F
C
S
N
I
E
K
S
A
W
-
E
S
----
A
T
L
T
C
K
P
S
A
L
I
D
K
L
K
E
Y
S
V
N
D
P
---
Y
S
G
K
T
V
T
G
G
I
I
T
I
T
D
S
N
W
---------
L
M
S
F
T
C
-
N
---
R
Q
P
H
F
P
E
-
Q
P
D
D
V
L
V
L
W
V
Y
A
L
F
M
D
K
E
G
N
Y
I
K
K
T
M
L
E
C
T
G
D
E
I
L
A
E
L
C
Y
H
L
G
I
-
E
D
Q
L
E
N
V
Q
--
K
N
-
T
-
I
V
R
--
T
A
F
M
P
Y
I
T
S
M
F
M
P
R
A
K
G
D
R
P
R
V
V
P
E
G
C
K
N
L
G
L
V
G
Q
F
V
E
T
N
-
N
D
V
V
F
T
M
E
S
S
V
R
T
A
R
-
I
A
V
Y
K
L
L
N
L
N
K
Q
V
P
D
I
N
P
L
Q
Y
D
I
R
H
L
L
K
A
A
K
T
L
N
D
D
K
P
F
---
V
G
E
G
L
L
-
R
K
V
L
K
G
T
Y
F
E
H
V
LP
A
G
E
E
H
E
S
F
I
A
E
H
V
N
K
F
R
E
W
V
K
G
IRG
38
Fugue
46.04
14%
-23
- C2 -
1GOS
1
AOFB_HUMAN
A:
[4-500]
-----------------------------------
K
C
D
V
-------------------------
V
V
V
G
G
G
I
S
G
M
A
A
A
K
L
L
H
D
S
G
L
----------
N
V
V
V
L
E
A
R
D
R
V
-------
G
G
R
T
Y
T
L
R
N
Q
K
V
K
Y
V
D
L
G
G
-----
S
Y
V
G
P
---
T
----
Q
--
N
R
I
L
R
L
A
K
E
L
G
-----------------
L
E
T
Y
K
V
N
E
V
E
R
L
I
H
H
V
K
G
-
K
S
Y
P
-
F
R
-
G
P
F
P
P
V
W
N
P
I
T
Y
---
L
D
H
N
N
F
-
W
R
---
T
M
D
D
M
G
R
E
I
P
S
D
A
P
W
K
A
P
L
A
----
E
E
W
D
N
M
T
M
----
K
-
E
L
L
D
K
-
L
C
W
T
E
S
A
K
Q
L
A
T
L
F
V
N
L
C
V
T
AE
T
H
E
V
S
A
L
W
F
L
W
Y
V
K
Q
C
G
G
T
T
R
I
I
S
T
T
N
G
G
------
Q
E
R
K
F
V
G
G
S
G
Q
V
S
E
R
I
M
D
L
L
G
D
R
V
K
L
E
R
--
P
V
I
Y
I
D
Q
T
R
E
N
V
L
V
E
T
L
N
H
E
M
Y
E
A
K
Y
V
I
S
A
I
P
--------
P
T
------
L
G
M
K
I
H
-
F
N
-----
P
P
L
P
M
M
R
N
Q
M
I
T
R
V
P
L
G
S
-
V
I
K
C
I
V
Y
Y
K
E
P
F
W
R
K
K
----
D
----------
Y
C
G
T
M
I
I
D
G
E
E
---
A
P
V
A
Y
T
L
D
D
T
K
P
E
G
N
Y
A
A
---------
I
M
G
F
I
L
A
H
---
K
A
R
K
L
A
R
-
L
T
K
E
E
R
L
K
K
L
C
E
L
Y
A
K
V
L
G
S
L
E
A
L
E
P
V
H
Y
E
E
K
N
W
C
E
E
Q
Y
S
G
G
C
Y
T
----------------------------
T
Y
F
P
P
G
I
L
T
Q
Y
G
R
V
L
R
Q
P
V
D
R
I
Y
F
A
G
--
T
E
T
A
-
T
H
W
S
G
Y
M
E
G
A
V
E
A
G
E
-
R
A
A
R
E
I
L
H
A
M
G
K
I
P
E
D
E
I
W
Q
S
E
P
E
---------
S
V
D
V
P
A
Q
P
I
T
T
T
F
L
E
-
R
H
L
P
S
V
P
G
L
L
R
L
--
I
G
L
T
T
--------------------
45
Fugue
44.72
12%
-33
- C2 -
1H83
3
PAO_MAIZE
A:
[5-463]
------------------------------------
P
R
V
-------------------------
I
V
V
G
A
G
M
S
G
I
S
A
A
K
R
L
S
E
A
G
I
---------
T
D
L
L
I
L
E
A
T
D
H
I
-------
G
G
R
M
H
K
T
N
F
A
--
G
I
N
V
E
L
G
ANWVE
G
V
N
G
G
---
K
----
M
--
N
P
I
W
P
I
V
N
S
T
L
K
L
R
N
F
R
S
-
D
F
D
Y
-
L
A
Q
N
V
Y
K
E
D
G
G
V
Y
D
E
D
Y
V
Q
----
K
R
I
E
------------
L
A
D
S
---
V
E
E
M
G
E
-
K
L
---
S
A
T
L
H
--------
A
S
G
R
D
D
M
----
S
I
L
A
M
Q
R
L
----
N
-
E
H
Q
P
N
G
P
A
T
P
V
D
M
V
V
D
Y
Y
K
F
D
Y
E
F
A
E
--
P
P
R
V
T
S
L
Q
N
T
V
P
L
A
T
F
S
D
F
G
D
D
V
Y
F
V
A
D
Q
-
R
G
Y
E
A
V
V
Y
Y
L
A
G
Q
Y
L
K
T
D
D
K
S
G
K
I
V
D
P
R
L
Q
L
N
K
--
V
V
R
E
I
K
Y
S
P
G
G
V
T
V
K
T
E
D
----
N
S
V
Y
S
A
D
Y
V
M
V
SAS
L
G
V
L
Q
S
------
D
L
I
Q
F
K
-
P
K
-----
L
P
T
W
K
V
R
A
I
--
Y
Q
F
D
M
A
V
-
Y
T
K
I
F
L
K
F
P
R
K
F
W
P
E
G
KGRE
F
F
L
Y
A
S
S
R
R
G
Y
Y
G
V
W
Q
E
F
E
K
Q
Y
---
P
-
D
A
N
V
L
L
V
T
V
T
D
---------------------
E
---
E
S
R
R
I
E
Q
-
Q
S
D
E
Q
T
K
A
E
I
M
Q
V
L
R
K
M
F
P
G
K
D
V
P
D
A
T
----
D
I
L
V
P
R
W
W
S
-------------------------
D
R
F
Y
K
G
T
F
S
N
W
P
V
G
V
N
R
Y
E
Y
D
Q
L
R
A
P
V
G
R
V
Y
F
T
G
--
E
H
T
S
-
E
H
Y
N
G
Y
V
H
G
A
Y
L
S
G
I
-
D
S
A
E
I
L
I
N
C
A
Q
K
K
M
C
-------------------------------------------------------------------------
41
Fugue
44.07
12%
-50
- C2 -
2BA9
4
?
A:
[2-424]
-------------------------------
S
I
S
K
D
S
R
I
-------------------------
A
I
I
G
A
G
P
A
G
L
A
A
G
M
Y
L
E
Q
A
G
F
---------
H
D
Y
T
I
L
E
R
T
D
H
V
-------
G
G
K
C
H
S
P
N
Y
H
-
G
R
R
Y
E
M
G
A
-----
I
M
G
V
P
---
S
----
Y
--
D
T
I
Q
E
I
M
D
R
T
-
G
D
K
V
D
G
P
-
K
L
R
R
-
E
F
L
H
E
D
G
E
I
Y
V
P
E
K
D
P
V
R
G
P
Q
V
-
M
A
A
V
-
Q
K
-
L
G
Q
L
L
A
T
K
Y
Q
G
Y
---
D
A
N
G
H
Y
-
N
K
---
V
H
E
D
L
M
L
P
F
D
E
F
L
A
L
N
G
C
E
A
----
A
R
D
L
W
I
N
P
----
F
-
T
A
F
G
Y
-
G
H
F
D
N
V
P
A
A
Y
V
L
K
Y
L
D
F
V
T
M
--
M
S
F
A
K
G
D
L
W
T
W
A
D
G
T
Q
A
M
F
E
H
L
N
A
T
L
E
H
P
-
A
----------
E
R
N
V
D
I
T
R
I
T
R
E
D
G
K
V
H
I
H
T
T
D
--
W
D
R
E
S
-----
D
V
L
V
L
T
--------------
V
P
--------
L
E
------
K
F
L
D
Y
S
-
D
A
-----
D
D
D
E
R
E
Y
F
S
--
K
--------------
I
I
H
Q
Q
Y
M
V
D
----
A
C
L
V
K
E
Y
P
T
I
S
G
Y
V
P
D
N
M
R
P
E
R
---
L
G
H
V
M
V
Y
Y
H
R
W
A
D
D
P
H
Q
I
---------
I
T
T
Y
L
L
-
R
---
N
H
P
D
Y
A
D
-
K
T
Q
E
E
C
R
Q
M
V
L
D
D
M
E
T
F
G
H
P
--------------------------------
V
--
E
K
I
I
-
E
E
Q
--
T
W
Y
Y
F
P
H
V
S
S
E
D
Y
K
A
G
W
Y
E
K
V
E
G
M
Q
G
R
R
N
T
F
Y
A
G
E
I
M
S
F
G
------
N
F
D
E
V
C
H
Y
S
K
-
D
L
V
T
R
F
F
V
--------------------------------------------------------------------------------
15
HHSearch
43.47
14%
-64
- C2 -
3NRN
1
?
A:
[1-263]
------------------------------------
M
R
A
-------------------------
V
V
V
G
A
G
L
G
G
L
L
A
G
A
F
L
----
A
R
--
N
--
G
--
H
E
I
I
V
L
E
K
S
A
M
I
-------
G
G
R
F
T
N
L
P
--
Y
K
G
F
Q
L
S
T
G
-----
A
L
H
M
I
PHG
E
----
D
--
G
P
L
A
H
L
L
R
I
L
G
A
K
V
E
-----
I
V
-----
N
S
N
P
------
K
G
K
I
L
W
E
-
G
-
K
I
F
H
Y
R
E
-
S
W
K
F
L
S
-----------
K
L
L
A
-
E
I
R
M
N
K
L
P
K
E
E
I
P
A
D
E
W
I
K
E
K
I
G
E
N
E
F
L
L
S
V
L
E
S
F
A
G
----
W
A
D
S
V
S
L
S
D
L
T
A
L
E
L
A
K
E
I
R
A
A
L
---------
R
W
G
G
P
-
G
L
I
R
G
G
C
K
A
V
I
D
E
L
E
R
I
I
M
E
N
-
K
G
K
I
L
T
R
K
E
V
V
E
I
N
I
E
E
K
----
K
V
---
Y
T
R
-
D
N
--
E
E
Y
-----
S
F
D
V
A
I
S
N
V
G
V
R
E
T
V
K
L
I
G
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
43.03
13%
-58
- C2 -
3KA7
1
?
A:
[1-258]
------------------------------------
M
K
T
-------------------------
V
V
I
G
A
G
L
G
G
L
L
S
A
A
R
L
----
S
K
--
A
--
G
--
H
E
V
E
V
F
E
R
L
P
I
T
-------
G
G
R
F
T
N
L
S
--
Y
K
G
F
Q
L
S
S
G
-----
A
F
H
M
L
P--
N
----
G
PG
G
P
L
A
C
F
L
K
E
V
E
A
S
V
-----
N
I
V
R
S
E
M
T
T
V
-
R
V
P
L
K
K
G
N
P
D
Y
V
K
G
F
K
D
I
S
F
N
-
D
F
-
P
-
S
L
L
S
Y
K
D
R
M
K
---
I
A
L
L
I
V
S
T
R
---
K
N
R
P
S
G
S
S
L
Q
A
W
I
K
S
Q
V
S
D
E
----
W
L
I
K
F
A
D
S
F
C
G
W
A
-
L
S
L
K
S
D
E
V
P
V
E
E
V
F
E
I
I
E
N
M
Y
---------
R
F
G
G
T
G
I
P
E
-
G
G
C
K
G
I
I
D
A
L
E
T
V
I
S
A
N
-
G
G
K
I
H
T
G
Q
E
V
S
K
I
L
I
E
N
G
----
K
A
A
G
I
I
A
--
D
D
--
R
I
H
-----
D
A
D
L
V
I
S
N
L
G
H
A
A
T
A
V
L
C
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
42.06
20%
-10
- C2 -
4OPU
3
?
A:
[2-453]
-------------------------------
M
K
E
L
K
Y
D
V
-------------------------
L
I
I
G
G
G
F
A
G
S
S
A
A
Y
Q
L
S
R
R
G
L
----------
K
I
L
L
V
D
S
K
P
W
N
RIGDKPC
G
D
A
V
S
K
A
H
F
D
K
L
G
M
P
Y
P
K
G
-----
E
E
L
E
N
---
K
----
I
--
N
---
G
I
K
L
Y
S
P
D
M
Q
-
T
V
W
-
T
V
N
H
-
E
G
F
E
L
N
--
A
P
L
Y
N
Q
-
R
V
L
K
E
A
Q
-
D
R
G
V
-
E
I
-
W
D
L
T
T
A
M
K
P
I
F
E
DGY
V
K
G
A
V
L
-
F
N
---
R
R
T
N
E
E
L
T
V
Y
---------------------
S
----
K
-
V
V
V
E
A
-
T
G
Y
S
R
S
F
R
S
K
L
---------------------------
P
P
E
L
P
I
T
E
D
L
D
D
K
-
D
------------------
A
D
V
A
Y
R
E
V
L
L
T
K
E
D
I
E
D
H
D
Y
L
R
I
F
I
D
Q
E
T
--
S
P
G
G
Y
W
W
Y
F
P
K
G
K
N
K
V
N
--------
V
G
------
L
G
I
Q
G
G
M
G
Y
-----
P
S
I
H
E
Y
Y
K
K
--
Y
L
D
K
Y
-----------------------
A
P
D
V
D
K
S
K
L
L
V
K
G
G
A
L
V
P
T
R
R
P
---
L
Y
T
M
A
W
N
G
-
I
I
V
I
G
D
S
G
F
TVNPVHGGG
K
G
S
A
M
I
-
S
---
G
Y
C
A
A
K
A
I
L
S
A
F
E
T
G
D
F
S
A
S
G
L
W
D
M
N
I
C
Y
V
N
E
Y
G
A
K
Q
A
S
L
D
I
F
R
R
F
L
Q
K
L
S
-
N
D
D
I
N
Y
G
M
K
--
K
K
I
I
-
K
E
----------
E
D
L
L
E
A
S
E
K
G
D
L
H
L
S
V
A
D
K
A
M
R
V
-----
I
S
G
L
G
-
R
P
S
L
L
F
K
L
K
A
V
A
E
S
M
-
K
K
I
K
E
L
Y
L
-------------------------
N
Y
P
R
S
P
S
S
L
G
S
W
R
R
E
-
V
D
N
V
L
T
E
F
N
K
S
L
--
S
------------------------
40
Fugue
40.62
13%
-36
- C2 -
2VQ7
5
?
A:
[8-450]
------------------------------------
T
R
I
-------------------------
A
I
L
G
A
G
P
S
G
M
A
Q
L
R
A
F
Q
S
A
Q
E
K
G
A
E
--
I
--
P
E
L
V
C
F
E
K
Q
A
D
W
-------
G
G
Q
W
-----------------------------------------
N
Y
T
W
R
T
G
L
D
E
N
G
E
-
P
V
H
S
-
S
M
Y
------------------------------
R
Y
L
W
S
N
G
P
K
E
---
C
L
E
---------------------
F
A
D
Y
T
F
D
E
----
H
F
G
K
P
I
A
S
----
Y
-
P
-------
P
R
E
V
L
W
D
Y
I
K
G
R
V
E
K
A
G
-----------
V
R
K
Y
I
R
F
N
T
A
V
R
H
V
E
F
N
E
D
S
Q
-----
T
F
T
V
T
V
Q
D
H
T
T
D
T
I
Y
S
A
A
F
----------------------
D
Y
V
V
C
C
T
G
------
H
F
S
T
P
Y
V
P
--------
E
F
------
E
G
F
E
K
------------
F
G
G
R
I
L
--
H
A
H
D
F
R
D
-
A
L
E
F
-----
K
D
K
T
V
L
L
----
V
G
S
S
Y
S
A
E
D
I
G
S
Q
C
Y
K
Y
G
A
K
K
L
---
I
S
C
Y
R
T
A
P
M
G
Y
K
W
P
E
N
W
D
---------
E
R
P
N
L
V
-
R
VDT
E
N
A
Y
F
A
D
-
G
S
S
E
K
V
D
A
I
I
L
C
T
G
Y
I
H
H
F
P
F
L
N
D
D
L
R
L
V
T
N
N
R
L
W
P
L
N
L
Y
K
G
V
V
W
E
D
N
-
P
K
F
F
Y
I
G
M
Q
D
-
Q
W
Y
--
S
F
N
M
F
D
A
Q
A
W
Y
A
R
D
V
I
M
G
R
L
P
L
P
S
K
E
E
M
K
A
D
S
M
A
W
R
E
K
E
L
-
T
L
V
T
A
E
E
M
Y
T
Y
Q
G
D
Y
I
Q
N
L
I
D
M
T
D
Y
P
S
F
D
I
P
A
T
N
K
T
F
L
E
W
K
H
H
K
K
E
N
I
M
T
F
R
D
H
S
Y
R
S
L
M
T
G
T
M
-
A
P
K
H
H
T
P
W
I
D
A
---
L
D
D
S
L
E
A
Y
L
S
---------------
19
HHSearch
35.22
22%
9
- C2 -
2IVD
1
PPOX_MYXXA
A:
[17-93]
------------------------------------
M
N
V
-------------------------
A
V
V
G
G
G
I
S
G
L
A
V
A
H
H
L
----
R
S
--
R
--
G
--
T
D
A
V
L
L
E
S
S
A
R
L
-------
G
G
A
V
G
T
H
A
--
L
A
G
Y
L
V
E
Q
G
-----
P
N
S
F
L
D--
R
----
E
--
P
A
T
R
A
L
A
A
A
L
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
34.89
11%
-11
- C2 -
1I8T
1
GLF_ECOLI
A:
[1-367]
-----------------------------------
M
Y
D
Y
-------------------------
I
I
V
G
S
G
L
F
G
A
V
C
A
N
E
L
K
K
L
N
K
----------
K
V
L
V
I
E
K
R
N
H
I
-------
G
G
N
A
Y
T
E
D
C
E
G
I
Q
I
H
K
Y
G
A
-----
H
I
F
H
T
---
N
----
D
--
K
Y
I
W
D
Y
V
N
D
L
V
E
F
N
R
F
T
N
-
S
P
---
L
A
I
Y
K
D
K
L
F
N
L
P
F
N
M
N
T
F
H
Q
M
W
-
G
V
K
D
-
P
Q
-
E
A
Q
N
I
I
N
A
Q
K
K
K
---
Y
G
D
K
V
P
-
E
N
---
L
E
E
Q
A
I
S
L
V
G
E
D
L
Y
Q
A
L
I
K
G
----
Y
T
E
K
Q
W
G
R
-------
S
A
K
E
-
L
P
A
F
I
I
K
R
I
P
V
R
F
T
F
D
N
N
Y
F
--
S
D
R
Y
Q
G
I
P
---
V
G
G
Y
T
K
L
I
E
K
M
L
E
G
V
D
V
K
L
G
I
D
F
L
K
D
K
D
S
L
A
S
K
A
H
R
I
I
Y
T
G
P
I
D
Q
Y
F
D
Y
R
F
G
--
A
L
E
Y
R
S
L
K
F
E
T
E
R
H
-
E
F
P
N
F
Q
G
N
A
V
I
N
F
T
D
A
N
--------
V
P
------
Y
T
------
R
-----
I
I
E
H
K
H
F
D
Y
--
V
E
T
K
H
T
V
V
T
K
E
Y
P
L
E
W
K
V
G
D
E
P
Y
Y
----
P
V
N
D
N
K
N
M
E
L
F
K
K
Y
R
E
L
A
S
R
E
D
K
V
I
F
G
G
R
L
A
E
Y
K
Y
Y
D
M
H
Q
V
I
S
---------
A
A
L
Y
Q
V
-
K
---
N
I
M
S
T
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
33.77
18%
-2
- C2 -
3NKS
1
PPOX_HUMAN
A:
[2-87]
-----------------------------------
G
R
T
V
-------------------------
V
V
L
G
G
G
I
S
G
L
A
A
S
Y
H
L
----
S
R
--
A
--
P
CP
P
K
V
V
L
V
E
S
S
E
R
L
-------
G
G
W
I
R
S
V
R
G
-
P
N
G
A
I
F
E
L
G
-----
P
R
G
I
R
---
P
AG
A
L
G
--
A
R
T
L
L
L
V
S
E
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
33.05
25%
0
- C2 -
3LOV
1
?
A:
[2-91]
---------------------------------
M
S
S
K
R
L
-------------------------
V
I
V
G
G
G
I
T
G
L
A
A
A
Y
Y
A
----
E
R
--
A
F
P
D
--
L
N
I
T
L
L
E
A
G
E
R
L
-------
G
G
K
V
A
T
Y
R
--
E
D
G
F
T
I
E
R
G
-----
P
D
S
Y
V
A--
R
----
K
--
H
I
L
T
D
L
I
E
A
I
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
32.29
26%
2
- C2 -
1SEZ
1
PPOM_TOBAC
A:
[13-104]
-----------------------------------
A
K
R
V
-------------------------
A
V
I
G
A
G
V
S
G
L
A
A
A
Y
K
L
----
K
I
--
H
--
G
--
L
N
V
T
V
F
E
A
E
G
K
A
-------
G
G
K
L
R
S
V
S
--
Q
D
G
L
I
W
D
E
G
-----
A
N
T
M
T
E--
S
----
E
--
G
D
V
T
F
L
I
D
S
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
31.67
29%
56
- C2 -
2Z3Y
1
KDM1A_HUMAN
A:
[103-181]
-------------------------------
P
T
K
K
T
G
K
V
-------------------------
I
I
I
G
S
G
V
S
G
L
A
A
A
R
Q
L
----
Q
S
--
F
--
G
--
M
D
V
T
L
L
E
A
R
D
R
V
-------
G
G
R
V
A
T
F
R
--
K
G
N
Y
V
A
D
L
G
-----
A
M
V
V
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------