@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0180: (2016-03-13 )
MKKKLTFKENMFIGSMLFGLFFGAGNLIFPIHLGQAAGSNVFIANLGFLITAIGLPFLGIIAIGISKTSGLFEIASRVNKTYAYIFTIALYLVIGPFFALPRLATTSFEIAFSPFLSPKQITLYLFIFSFVFFVIAWFFARKPSRILEYIGKFLNPVFLVLLAIILLFAFIHPLGGISDAPISKQYQSHALFNGFLDGYNTLDALASLAFGIIIVATIKKLGIENPTDIAKETIKSGTISIIMMGIIYTLLAIMGTLSIGHFKLSENGGIALAQITQYYLGNYGIVLLSLIVMVACLKTAIGLITAFSETFEHLFPKMNYLAIATVVSFISFLFANVGLTKIIMYSVPVLMFLYPLAIALIVLTLFSSKFHHSKIIYQCTIFFTMIAALVDGLKASPEFISSTSFSQTLINFSQKYLPLSDIGMGWVVLSLIGFIIGFIIYKIKHRKIP
Atome Classification :
(20 SA)
....-------------.....10........20..-.....-.30........40......-...50......-..60.---..-....-.---70...--------...-..80.-.......90.-.......100.....----------..110.......120....-...130.-...-...140.......150-........160.......170...---....180.-.....-..----190..-..-..--..-200-.-.-.....----.210....--..--.220--..----------..-.-..230........240...-..---..250--.--......--260-------.-.......270.......280.......290.......300..---......310...-..------..320------.-------.......330.....--.--.340---.........350.......360.......370..---......380---------........390.......400......-.410.......420.----....--...430.-......440.......-----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKKK-------------
L
T
FKEN
M
F
I
G
S
M
L
F
G
L
F
FG-AG
N
L
I
-
F
P
I
HLGQAAGS
N
-
V
F
I
A
N
L
-
G
F
L
I
T
A
I
G
L
P
F
-
L
G
I
I
A
---
I
G-ISKT-
S
---
G
L
F
E
I
--------
A
S
R
-VNK
T
Y
-
A
Y
I
F
T
I
A
L
Y
L
-
V
I
G
P
F
F
ALPRLAT
T
S
----------
F
E
I
A
FSPFLSPK
Q
I
T
L
Y
L
F
-
I
F
S
F
V
F
F
-
V
I
A
-
W
F
F
AR
K
P
S
R
I
L
E
Y
I
G
--
K
F
L
N
P
V
F
L
V
L
L
A
I
I
L
L
F
A
F
I
H
PLG---GISDA
P
-
I
-
S
K
Q
Y
Q
-
S
H
----
A
-
L
F
N
-
G
F
-LD--GY-
N
T
--
L
-
D
-
A
L
A
S
L
----
A
F
G
I
I
I
V
A
--
T
I
--
K
K
LG--IE----------N
P
-
T
-
D
I
A
K
-
E
T
I
KSG
T
I
S
I
I
M
M
G
-
I
I
---
Y
T
L
L
A
--
I
--
M
G
TL
S
I
--
G
H
--------
F
-
K
LSENGG
I
A
L
A
Q
I
T
Q
Y
Y
LGN
Y
G
I
V
L
L
S
L
I
V
M
V
A
C
L
K
T
A
-
I
G
L
---
I
T
A
F
S
E
T
F
E
H
L
F-PK------
M
N
Y
L
-------
A
-------
I
A
T
V
V
S
F
I
S
F
L
F
A
NV--
G
--
L
T
-----
K
I
I
M
Y
S
V
P
V
L
M
F
L
Y
P
L
A
I
A
L
I
V
L
T
L
F
SSKF-HH
S
---
K
I
I
Y
Q
C
T
I
----------
F
F
T
M
I
A
A
L
V
DGLKAS
P
E
F
ISST
S
F
S
Q
T
-
L
I
N
F
S
Q
K
YL
P
L
S
D
-
I
----
G
M
G
W
--
V
V
L
S
L
I
G
-
F
I
I
G
F
I
I
Y
K
IKHRKIP-----
15
Fugue
90.13
18%
-160
* C4 *
4US3
13
?
A:
[10-450]
--
G
R
-------------
E
Q
W
A
S
R
L
G
F
I
L
A
A
M
G
S
A
V
G
-
L
G
N
I
W
-
R
F
S
Y
V
T
G
E
N
G
G
A
-
A
F
L
L
V
Y
-
L
G
F
I
A
L
I
G
I
P
I
V
L
A
E
F
T
---
I
G
-
R
R
A
Q
-
S
D
A
V
G
S
F
E
K
L
APGKPWK
V
A
G
-
L
M
G
V
A
-
A
G
F
L
I
L
S
F
Y
G
-
V
I
A
G
W
I
L
F
Y
L
F
N
Y
I
T
GQLWSAPAEG
F
G
G
F
F
E
G
F
I
A
N
P
--
T
L
P
L
F
-
W
Q
A
L
F
M
I
-
A
T
I
-
W
I
V
A
I
G
V
K
K
G
I
E
R
S
N
--
K
I
L
M
P
L
L
G
V
L
L
I
A
L
A
I
Y
S
L
T
L
G
G
A
---
K
E
G
L
A
F
-
L
F
S
P
D
W
S
-
A
L
----
K
-
D
P
G
-
V
Y
-
L
A
--
A
I
-
S
Q
--
A
-
F
-
F
T
L
S
L
----
G
M
G
A
L
I
T
Y
--
G
S
--
Y
-----
V
S
----------
K
D
-
S
-
R
L
P
G
-
A
A
V
S
V
A
G
L
D
T
-
A
F
A
-
I
I
---
A
G
I
M
I
--
F
--
P
A
V
F
A
L
--
G
------------
L
S
P
S
G
G
P
G
----------------
L
V
F
V
V
L
P
D
I
F
D
S
--------
I
R
L
G
P
I
V
G
I
A
F
F
-
I
L
------
L
G
A
A
-------
A
-------
L
S
S
A
V
S
L
L
E
V
P
V
A
Y
F
--
M
--
R
K
F
DWS
R
K
Q
A
A
I
T
L
G
V
I
I
T
L
L
G
I
P
S
S
L
S
F
G
V
L
G
E
V
T
I
-
I
P
G
---
L
N
I
F
D
S
V
D
----------
F
I
A
S
S
V
F
L
P
L
G
G
M
I
I
A
L
F
I
G
W
G
W
K
T
S
D
-
A
L
A
E
S
D
--
L
T
D
S
V
-
W
----
G
K
L
W
--
I
L
S
L
R
F
I
-
A
P
I
A
I
L
I
V
F
L
S
A
F
--------
19
Fugue
68.99
18%
-128
- C2 -
4X2Z
1
A:
[9-309]
-
Q
K
T
-------------
I
Y
L
T
E
D
---
G
V
K
Y
R
S
I
V
L
K
-
P
G
D
S
---
L
G
Q
F
G
Q
V
Y
A
K
N
-
K
I
V
--------------------------------------
F
T
A
--------
D
D
V
-
E
D
K
E
I
-
L
Y
V
-------------------
P
T
T
D
----------
K
S
I
L
E
Y
Y
G
L
D
A
Q
K
Y
V
I
Y
L
Q
-
T
L
A
Q
K
W
N
------
V
Q
Y
R
D
N
F
L
I
L
E
W
R
D
--
G
N
----
C
W
I
S
S
A
I
V
L
L
Q
A
--------------------------------------------------------
A
K
I
----
R
F
K
G
F
L
T
E
--
A
W
--
A
K
L
L
--
G
G
----------
D
P
-
T
-
D
F
V
A
-
W
C
Y
A
S
C
T
A
K
V
---
G
-
D
F
---
S
D
A
N
W
--
L
--
L
A
N
L
A
---
E
H
--------
F
-
D
A
D
Y
T
N
----
A
F
L
K
K
R
V
S
C
N
C
G
I
K
S
Y
E
L
R
G
L
E
A
C
I
Q
P
V
-
R
---------
A
T
N
L
L
H
F
K
-
T
Q
------
Y
S
N
C
-------
P
-------
T
C
G
A
N
N
T
D
E
V
I
E
A
S
L
--
P
--
Y
L
-----
L
L
F
A
T
D
G
P
A
T
V
D
C
D
E
D
A
V
G
T
V
V
F
V
G
S
T
N
-------------
S
G
H
C
----------
Y
T
Q
A
A
G
Q
A
F
D
N
L
A
K
D
R
K
F
G
K
K
S
P
Y
I
T
A
M
Y
T
R
F
A
F
K
--------------------------------------
N
E
T
S
-----
5
HHSearch
68.53
17%
-123
- C4 -
3GIA
5
Y609_METJA
A:
[5-302]
-
N
K
K
-------------
L
S
L
W
E
A
---
V
S
M
A
V
G
V
M
I
G
-
A
S
I
F
S
-
I
F
G
V
G
A
K
I
A
G
R
N
-
L
P
E
T
F
I
-
L
S
G
I
Y
A
L
L
V
A
Y
-
S
Y
T
K
L
---
G
A
-
K
I
V
S
N
A
---
G
P
I
A
F
--------
I
H
K
A
I
G
D
N
I
I
T
G
A
L
S
I
L
L
W
---
M
S
Y
V
I
S
I
A
L
F
A
K
G
F
----------
A
G
Y
F
L
P
L
I
N
A
P
I
-
N
T
F
N
I
A
-
I
T
E
I
G
I
V
-
A
F
F
-
T
A
L
N
F
F
G
S
K
A
V
G
R
A
E
--
F
F
I
V
L
V
K
L
L
I
L
G
L
F
I
F
A
G
L
I
T
I
-----
H
--
P
S
Y
------
V
--
I
P
----
D
-
L
A
P
S
A
V
-
S
G
--
M
I
-
F
A
----
S
-
A
I
F
F
L
----
S
Y
M
G
F
G
V
I
--
T
N
--
A
S
E
H
--
I
E
----------
N
P
K
K
-
N
V
P
R
-
A
I
F
I
S
I
L
I
V
M
F
V
Y
V
G
V
A
---
I
S
A
I
G
--
N
--
L
P
I
D
E
L
--
I
K
--------------
A
S
E
N
A
L
A
V
A
A
K
P
F
L
G
N
L
G
F
L
L
I
S
I
G
A
L
F
S
I
S
S
A
M
-
N
A
T
---
I
Y
G
G
A
N
V
A
Y
S
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
68.45
13%
-154
- C4 -
2XQ2
3
SGLT_VIBPH
A:
[54-450]
-----------------------
W
A
V
G
A
S
L
I
A
A
N
I
S
-
A
E
Q
F
I
-
G
M
S
G
S
G
Y
S
I
G
L
A
-
I
A
S
Y
E
W
-
M
S
A
I
T
L
I
I
V
G
K
-
Y
F
L
P
I
---
F
I
-
E
K
G
I
-
Y
---
T
I
P
E
F
--------
V
E
K
R
F
N
K
K
L
-
K
T
I
L
A
V
F
W
I
S
--
L
Y
I
F
V
N
L
T
S
V
L
Y
L
G
----------
G
L
A
L
-
E
T
I
L
G
-----
I
P
L
M
Y
S
I
L
G
L
A
L
-
F
A
L
-
V
Y
S
I
Y
G
G
---
V
V
W
T
D
--
V
I
Q
V
F
F
L
V
L
G
G
F
M
T
T
Y
M
A
V
S
F
I
G
G
---
T
D
G
W
F
A
G
V
-
S
K
M
V
D
A
A
P
GHFE
M
-
I
L
D
-
Q
S
N
P
Q
YM
N
L
-
P
G
--
I
A
V
-
L
I
G
G
L
W
V
A
N
L
Y
Y
W
G
F
N
Q
--
Y
I
I
Q
R
T
L
A
--
A
K
----------
S
V
-
S
-
E
A
Q
K
-
G
I
V
F
A
A
F
L
A
L
I
V
P
F
L
V
V
---
L
P
G
I
A
A
Y
V
--
I
T
S
D
P
Q
L
M
A
S
L
GN-----
L
-
P
S
A
A
N
A
D
K
A
Y
P
W
L
T
-
Q
F
L
P
V
G
V
K
G
V
V
F
A
A
L
A
A
A
I
V
S
S
L
-
A
S
M
---
L
N
S
T
A
T
I
F
T
M
D
I
-
Y
K
EYISPD
S
G
D
H
-------
K
L
V
N
V
G
R
T
A
A
V
V
A
L
I
I
A
A
L
I
A
P
M
LG
G
--
I
G
-----
Q
C
F
Q
Y
I
Q
E
Y
T
G
L
V
S
P
G
I
L
A
V
F
L
L
G
L
F
W
K
K
------------------------------------------------------------------------------------------------------------
16
Fugue
67.60
18%
-110
- C3 -
4LZ6
-
?
A:
[1-446]
Q
K
Q
Q
SERLGTEAIPKL
L
R
S
L
S
I
P
A
M
I
G
M
F
V
M
A
L
Y
N
V
-
V
D
T
I
F
-
I
S
Y
A
V
G
I
E
G
V
A
G
-
V
T
I
A
F
P
-
I
M
M
I
M
M
S
M
A
G
A
-
L
G
I
G
G
---
A
S
V
I
S
R
R
-
L
---
G
E
R
R
---------
G
E
E
-
A
N
Q
V
F
-
G
N
I
L
T
V
I
L
V
L
-
S
V
I
G
F
I
S
A
F
T
L
L
G
P
A
----------
L
Q
L
F
G
A
T
S
V
T
Q
G
Y
A
T
D
Y
L
F
-
P
I
L
L
--
G
-
S
I
F
-
F
F
F
A
F
A
A
N
N
I
I
R
S
E
G
N
A
T
F
A
M
V
T
M
I
V
P
A
V
L
N
I
L
L
D
V
L
F
I
F
G
LNM
G
V
L
G
A
S
-
I
-
A
T
V
I
A
-
Q
A
----
S
-
V
T
G
-
L
V
-
L
R
--
Y
F
-
L
T
--
G
-
K
-
S
T
L
S
L
----
H
W
S
D
L
-----
R
M
--
K
G
S
V
--
I
K
----------
E
V
-
C
-
L
V
G
L
P
A
F
V
Q
Q
S
S
A
S
L
M
M
I
A
-
I
N
---
S
M
L
L
R
--
F
--
G
S
D
F
Y
V
--
G
V
--------
F
-
G
L
V
Q
R
--------------
I
M
M
F
V
M
M
P
M
M
G
I
M
Q
A
M
Q
P
I
-
V
G
Y
NYG
A
K
Q
Y
S
R
L
R
E
T
V
M
-
L
G
------
F
K
V
A
-------
T
-------
I
F
S
I
G
I
F
A
L
L
M
L
F
P
E
--
A
--
L
L
-----
R
V
F
T
A
D
R
E
V
I
Q
A
G
V
S
A
M
H
I
L
F
C
V
T
F
L
I
G
A
Q
-
I
V
A
---
G
G
L
Y
Q
S
L
------------------------
G
K
P
K
Q
A
L
I
L
S
L
S
R
Q
-
I
I
F
L
I
P
L
V
L
I
L
P
H
-
I
FGLS
G
V
W
W
AF
P
I
A
D
V
L
S
-
F
I
L
T
V
V
L
L
Y
R
D
R
N
V
F
F
LK---
4
HHSearch
67.20
14%
-126
- C4 -
3L1L
2
ADIC_ECO57
A:
[7-304]
-
A
H
K
-------------
V
G
L
I
P
V
---
T
L
M
V
S
G
A
I
M
G
-
S
G
V
F
L
-
L
P
A
N
L
A
S
T
-
G
G
I
-
A
I
Y
G
W
L
-
V
T
I
I
G
A
L
G
L
S
M
-
V
Y
A
K
M
---
S
F
-
L
D
P
S
P
G
---
G
S
Y
A
Y
--------
A
R
R
C
F
G
P
F
L
-
G
Y
Q
T
N
V
L
Y
W
---
L
A
C
W
I
G
N
I
A
M
V
V
I
G
----------
V
G
Y
L
S
-
Y
F
F
P
I
L
K
D
P
W
V
L
T
-
I
T
C
V
V
V
L
-
W
I
F
-
V
L
L
N
I
V
G
P
K
M
I
T
R
V
Q
--
A
V
A
T
V
L
A
L
I
P
I
V
G
I
A
V
F
G
W
F
W
--
F
---
R
--
G
E
T
------
Y
--
M
A
-----------------
A
I
-
Q
S
--
T
-
L
-
N
V
T
L
W
----
S
F
I
G
V
E
S
A
--
S
V
--
A
A
G
V
--
V
K
----------
N
P
-
K
R
N
V
P
I
-
A
T
I
G
G
V
L
I
A
A
V
C
Y
V
L
S
T
---
T
A
I
M
G
--
M
--
I
P
N
A
A
L
--
R
V
--------
S
-
A
---
S
P
F
---
G
D
A
A
R
M
A
L
G
D
T
A
G
A
I
V
S
F
C
A
A
A
G
C
L
G
S
L
-
G
G
W
---
T
L
L
A
G
Q
T
A
K
A
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
64.03
12%
-118
* C3 *
2YIJ
-
DSEL_ARATH
A:
[19-417]
-----------------
F
A
K
R
W
R
D
L
S
G
Q
N
H
W
K
---
G
M
L
Q
P
L
D
-
Q
D
L
R
E
Y
I
I
H
Y
G
E
M
A
Q
A
G
Y
D
-
T
F
N
I
N
T
E
S
-
Q
F
-
A
G
A
S
I
-------
Y
S
R
-
K
---
D
F
F
A
K
--------
V
G
L
-
E
I
A
H
P
-
Y
T
K
Y
K
V
T
K
F
I
-----------
Y
A
T
S
D
----------
I
H
V
P
E
S
F
L
L
F
P
I
S
W
S
K
E
S
N
-
W
----------M
G
Y
V
A
V
T
D
D
Q
G
T
A
L
L
G
--
R
-----
R
D
I
V
V
S
W
R
G
S
V
Q
P
F
E
F
G
L
---
V
N
A
I
K
I
-
F
-
G
E
R
N
D
-
Q
V
----
Q
-
I
H
Q
-
G
W
-
Y
S
--
I
Y
M
S
Q
DE
R
-
S
-
P
F
T
K
T
----
N
A
R
D
Q
V
L
R
--
E
V
--
G
R
L
L
--
E
K
----------
Y
------------
K
D
E
E
V
S
I
T
I
C
G
-
H
-----
S
L
G
A
--
A
--
L
A
T
L
S
A
--
T
D
--------
I
-
V
A
N
G
Y
N
R
P
K
S
R
P
D
K
S
C
-----------
P
V
T
A
F
V
F
A
S
P
R
-
V
G
--------
D
S
D
F
R
K
L
F
-
S
G
------
L
E
D
I
-------
R
-------
V
L
R
T
R
N
L
P
D
V
I
P
I
Y
P
--
P
--------------------
I
G
Y
S
E
V
G
D
E
F
P
I
D
T
R
K
S
P
Y
M
K
S
P
GN
L
A
T
F
H
C
L
E
G
----------
Y
L
H
G
V
A
G
T
-
Q
G
T
N
K
A
D
L
F
R
L
D
V
E
R
A
I
G
-
L
V
N
K
S
V
D
G
L
K
D
E
C
M
V
----
P
G
K
W
--
R
V
L
K
N
K
G
M
A
Q
Q
D
D
G
S
W
E
L
V
D
H
E
I
D
DNEDL
21
Fugue
59.83
17%
-158
- C3 -
4IIK
18
SIDD_LEGPH
A:
[1-314]
M
R
-------------------------------------
S
I
I
-
T
Q
I
C
N
G
V
L
H
G
Q
---------------------------------
S
Y
Q
-
S
---
G
------------
S
N
D
-
L
D
K
G
N
-
S
E
I
F
A
S
S
L
F
V
-
H
L
N
E
Q
G
K
E
I
K
D
S
D
D
K
----------
I
V
I
G
Y
T
K
D
G
------------
M
A
F
Q
I
V
-
V
D
G
--
F
Y
G
C
E
R
Q
A
V
F
S
F
I
D
--
N
Y
V
---------
L
P
L
I
D
N
F
S
L
D
L
T
---
R
Y
P
D
------
S
K
K
V
-
T
E
----
S
-
L
I
H
-
T
I
-
Y
S
--
L
R
-
S
K
--
H
-
A
-
P
L
A
E
F
----
T
M
S
L
C
V
T
Y
--
Q
K
--
D
E
----------------------------------
Q
L
F
C
A
G
-------------------
F
G
I
--
G
---------------
D
T
G
I
A
I
K
R
-------
N
E
G
T
-----
I
E
Q
L
V
C
H
T
E
V
-
D
G
F
---
K
D
A
F
D
---------
N
------
Y
S
S
A
-------
N
-------
I
D
L
V
I
E
R
------
N
S
--
V
--
F
N
-----
T
K
V
M
P
G
D
E
L
V
G
Y
T
Y
V
P
P
M
L
E
M
T
E
K
E
F
E
V
E
----
K
---
R
I
V
R
H
L
N
L
DPGNFDDKDP
L
F
S
Q
L
L
Q
V
V
K
S
K
Q
K
Q
L
V
E
Q
A
K
E
T
G
Q
I
Q
-
R
F
G
--------
D
D
-
F
----
T
V
G
R
--
L
V
I
P
D
------
Q
L
L
I
N
Q
L
R
I
H
A
L
S
-----
7
HHSearch
57.58
13%
-108
- C4 -
3DH4
3
?
A:
[60-421]
------------------------
A
V
G
A
S
L
I
A
A
N
I
S
-
A
E
Q
F
I
-
G
M
S
G
S
G
Y
S
I
G
L
A
-
I
A
S
Y
E
W
-
M
S
A
I
T
L
I
I
V
G
K
-
Y
F
L
P
I
---
F
I
-
E
K
G
I
-
Y
---
T
I
P
E
F
--------
V
E
K
R
F
N
K
K
L
-
K
T
I
L
A
V
F
W
I
S
-
L
-
Y
I
F
V
N
L
T
S
V
L
Y
L
G
----------
G
L
A
L
-
E
T
I
L
G
-----
I
P
L
M
-
Y
S
I
L
G
L
A
L
F
A
L
-
V
Y
S
I
------
V
V
W
T
D
--
V
I
Q
V
F
F
L
V
L
G
G
F
M
T
T
Y
M
A
V
S
F
I
G
G
---
T
D
G
W
F
A
G
V
-
S
K
M
V
D
A
A
P
GHFE
M
-
I
L
D
Q
S
N
-
P
Q
YM
N
L
-
P
G
--
I
-
A
V
L
I
G
G
L
W
V
A
N
L
Y
Y
W
G
F
N
Q
--
Y
I
--
I
Q
R
T
L
A
A
K
----------
S
V
-
S
-
E
A
Q
K
-
G
I
V
F
A
A
F
L
K
L
I
V
P
F
L
V
V
---
L
P
G
I
A
A
Y
V
--
I
T
S
D
P
Q
L
M
A
S
L
GDIAATN
L
-
P
S
A
A
N
A
D
K
A
Y
P
W
L
T
-
Q
F
L
P
V
G
V
K
G
V
V
F
A
A
L
A
A
A
I
V
S
S
L
-
A
S
M
---
L
N
S
T
A
T
I
F
T
M
D
I
Y
K
E
YISPD-
S
G
D
H
K
L
V
N
V
G
R
T
-------
A
A
V
V
A
L
I
I
A
C
L
I
A
P
M
--
L
GG
I
G
-----
Q
A
F
Q
Y
I
Q
E
Y
T
G
L
V
S
P
G
I
L
A
V
F
L
L
G
L
F
W
K
K
------------------------------------------------------------------------------------------------------------
6
HHSearch
56.82
10%
-135
- C4 -
2JLN
2
?
A:
[27-382]
-----------------
V
G
P
F
S
L
---
A
A
I
W
F
A
M
A
I
Q
-
V
A
I
F
I
-
A
A
G
Q
--
M
T
S
S
F
Q
-
V
W
Q
V
I
V
-
A
I
A
A
G
C
T
I
A
V
I
-
L
L
F
F
T
Q
S
A
A
I
-
R
W
-
G
-
I
---
N
F
T
V
A
--------
A
R
M
P
F
G
I
R
G
-
S
L
I
P
I
T
L
K
A
L
L
S
L
F
W
F
G
F
Q
T
W
L
G
A
L
A
----------
L
D
E
I
T
R
L
L
T
G
F
T
----
N
L
P
-
L
W
I
V
I
F
G
-
A
I
Q
-
V
V
T
T
F
Y
G
I
T
F
I
R
W
M
N
--
V
F
A
S
P
V
L
L
A
M
G
V
Y
M
V
Y
L
M
L
D
G
A
D
V
---
S
--
L
G
E
-
V
-
M
S
-
M
--
G
G
----
E
N
P
G
M
-
P
F
-
S
T
--
A
I
-
M
I
-------
F
V
G
G
----
W
I
A
V
V
V
S
I
--
H
D
--
I
V
K
E
--
C
K
VDPNAS
R
E
G
Q
T
K
-
A
-
D
A
R
Y
-
A
T
A
-
Q
-
W
L
G
M
V
----
P
A
---
S
I
I
F
G
--
F
--
I
G
A
A
S
M
--
V
L
--------
V
-
G
E
W
-
N
P
V
I
A
I
T
E
V
V
G
G
-
V
S
I
P
M
A
I
L
F
Q
V
F
V
L
L
A
T
W
S
T
N
P
A
A
N
---
L
L
S
P
A
Y
T
L
C
S
T
F
-
P
R
V-----
F
T
F
K
-------
T
-------
G
V
I
V
S
A
V
V
G
L
L
M
M
P
W
--
Q
--
F
A
-----
G
V
L
N
T
F
L
N
L
L
A
S
A
L
G
P
L
A
G
I
M
I
S
D
Y
F
---------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
47.17
35%
-33
- C4 -
3GIA
1
Y609_METJA
A:
[199-278]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
Y
M
----
G
F
G
V
I
T
N
A
--
S
E
--
H
-----
I
E
----------
N
P
-
K
----
K
-
N
V
P
R
A
I
F
I
S
I
L
I
V
M
-
F
V
---
Y
V
G
V
A
--
I
S
A
I
G
N
L
P
I
--
D
E
--------
L
I
K
A
S
E
N
---
A
L
A
V
A
A
K
P
F
L
G
N
L
G
F
L
L
I
S
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
46.21
35%
-16
- C4 -
3GI8
-
Y609_METJA
C:
[199-278]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
Y
M
----
G
F
G
V
I
T
N
A
--
S
E
--
H
-----
I
E
----------
N
P
-
K
----
K
-
N
V
P
R
A
I
F
I
S
I
L
I
V
M
-
F
V
---
Y
V
G
V
A
--
I
SA
I
G
N
L
P
I
--
D
E
--------
L
I
K
A
S
E
N
---
A
L
A
V
A
A
K
P
F
L
G
N
L
G
F
L
L
I
S
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
44.93
35%
-29
- C4 -
3GI9
-
Y609_METJA
C:
[199-278]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
Y
M
----
G
F
G
V
I
T
N
A
--
S
E
--
H
-----
I
E
----------
N
P
-
K
----
K
-
N
V
P
R
A
I
F
I
S
I
L
I
V
M
-
F
V
---
Y
V
G
V
A
--
I
S
A
I
G
N
L
P
I
--
D
E
--------
L
I
K
A
S
E
N
---
A
L
A
V
A
A
K
P
F
L
G
N
L
G
F
L
L
I
S
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
44.11
15%
-53
- C3 -
1I50
-
RPAB2_YEAST
F:
[72-155]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
---
A
I
P
K
D
-----------
Q
----
R
-
A
T
T
-
P
Y
-
M
T
--
K
Y
-
E
R
--
A
-
R
-
I
L
G
T
R
----
A
L
Q
I
S
M
N
A
PV
F
V
--
D
L
E
G
--
E
T
----------
D
P
-
L
-
R
I
A
M
-
K
E
L
A
E
K
K
I
P
L
V
I
R
R
-
Y
L
PDG
S
F
E
D
W
--
S
--
V
E
E
L
I
V
--
D
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
26.34
11%
-26
- C4 -
2JLN
-
?
A:
[91-167]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
A
A
R
M
P
F
G
I
R
G
S
L
I
P
I
T
L
K
A
L
L
S
L
F
W
F
-
G
F
Q
---
T
W
L
G
A
L
A
L
D
E
I
T
-
R
L
L
TGF--
T
N
L
P
-------
L
-------
W
I
V
I
F
G
A
I
Q
V
V
T
T
F
Y
--
G
--
I
T
-----
F
I
R
W
M
------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
23.42
22%
38
- C4 -
2A65
4
?
A:
[10-72]
------------------
T
R
L
G
L
---
I
L
A
M
A
G
N
A
V
G
-
L
G
N
F
L
R
F
P
V
Q
A
A
E
N
G
G
G
A
-
F
M
I
P
Y
I
I
A
F
L
L
V
G
I
P
L
M
W
-
I
E
W
A
M
---
G
R
-
Y
G
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
21.72
12%
382
- C4 -
1JB0
-
PSAI_THEEB
I:
[18-34]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
C
W
--
L
M
P
T
V
V
M
-
G
L
L
F
L
Y
I
--------------
11
HHSearch
14.97
10%
412
- C4 -
2WSC
-
PSAI_PEA
I:
[12-30]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
L
--
L
F
P
A
V
A
M
-
A
S
L
F
L
H
V
E
K
------------
12
HHSearch
8.02
17%
378
- C4 -
2WSW
-
?
A:
[89-112]
--
P
E
-------------
F
S
T
A
S
W
---
I
F
M
M
F
A
S
C
T
S
-
A
A
V
L
F
-
W
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
7.66
30%
-
- C1 -
2AXT
-
PSBT_THEEB
T:
[1-1]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
T
I
T
Y
V
F
I
F
-
A
C
I
I
A
L
F
-
F
F
A
-
I
F
F
-
R
E
P
P
R
I
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------