@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0233: (2016-03-13 )
MKSLFEKAQQFGKSFMLPIAILPAAGLLLGIGGALSNPNTVKAYPILDITLLQNIFTLMSAAGSIVFQNLPVIFAIGVAIGLSRSDKGTAGLAALLGFLIMNATMNGLLTITGTLAKDQLAQNGQGMVLGIQTVETGVFGGIITGIMTAILHNKYHKVVLPPYLGFFGGSRFVPIVTAFAAIFLGVLMFFIWPSIQAGIYHVGGFVTKTGAIGTFVYGFILRLLGPLGLHHIFYLPFWQTALGGTLEVKGHLVQGTQNIFFAQLGDPDVTKYYSGVSRFMSGRFITMMFGLCGAALAIYHTAKPEHKKVVGGLMLSAALTSFLTGITEPLEFSFLFVAPILYVIHAFFDGLAFMMADIFNITIGQTFSGGFIDFLLFGVLQGNSKTNYLYVIPIGIVWFCLYYIVFRFLITKFNFKTPGREDKAAAQQVEATERAQTIVAGLGGKDNIEIVDCCATRLRVTLNQNDKVDKVLLESTGAKGVIQQGTGVQVIYGPHVTVIKNEIEELLGD
Atome Classification :
(20 SA)
.........10........20--.........30........40...--.....50-----........60........70---........80......---..90........100.......110.......120.......130.......140.......150......----..160.......170.......180.......190---.........200-......--.210.......220.........230..-----.....240.......250.......260.......270.......280...-....290....----...300.......310.......320.......330..-.....-----340----.......350.......360...---....370.......380.......390...-----....400.......410.--......---420.......430.......440.......450.......460....--..-.470...-....480.-.......490-..-.-....500.......----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
S
L
F
E
K
A
Q
Q
F
G
K
SFM
L
P
I
A
---
I
LPA
A
G
L
L
L
GIGGALSNPN
T
V
K
A
Y
--
P
I
L
D
I
T
L
-----
L
Q
N
I
F
T
L
M
S
A
A
G
S
I
V
F
QNL
P
---
V
I
F
A
I
G
V
AIGLSRSDK---G
T
A
G
L
A
A
L
L
G
F
L
I
M
N
A
TMN
G
L
L
T
I
TGT
L
A
K
D
Q
L
AQNG
Q
G
M
V
L
G
I
Q
T
V
E
T
GV
F
G
G
I
I
T
G
I
M
T
A
I
-
L
HNKY
H
K
----
V
VLP
P
Y
L
G
FFGG
S
R
F
V
P
I
V
T
A
F
A
A
I
F
L
G
V
L
M
F
F
-----
I
W
P
S
IQAG
I
Y
HV-G
G
F
V
TK--TGA
I
G
T
F
V
Y
G
F
I
--
L
R
L
L
G
P
L
G
L
H
H
I
F
Y
-----
L
P
F
W
Q
T
ALG
G
T
L
E
V
K
G
H
L
VQGTQ
N
I
F
F
A
QLGD
P
D
V
T
K
Y
Y
S
G
V
S
R
F
MSG
R
F
I
-
T
M
M
F
G
L
C
G
A
A
L
----
A
I
YHTAKP
E
H
K
K
V
V
G
G
L
M
L
S
A
A
L
T
S
F
L
T
GITEP
L
E
F
S
F
-
L
F
V
A
P
-----
I
L
Y
----
V
I
H
A
F
F
D
G
L
A
F
M
M
A
D
I
F
N
I
TIGQ---TFSG
G
F
I
D
F
L
L
F
G
V
LQGNSKT
N
Y
L
Y
V
I
P
I
G
-----
I
V
W
F
C
L
Y
Y
I
V
F
R
F
L
I
T
K
F--NFKTPG---RE
D
K
A
A
A
Q
Q
V
E
A
T
E
R
A
Q
T
I
V
AGLGGKD
N
I
E
I
V
D
CC
A
T
R
L
R
V
T
LNQND--
K
V
-
D
K
V
L
L
ES-TGAK
G
V
-
I
-QQGT
G
V
Q
V
I
Y-GP-H-
V
T
V
I
K
N
E
I
E
E
L
LGD----------
7
HHSearch
80.93
14%
-117
- C2 -
3QNQ
8
?
A:
[17-426]
--
A
E
Q
R
H
L
L
A
I
R
D
G
L
V
L
T
M
P
---
F
L
I
I
G
S
I
F
L
I
I
S
T
L
P
I
P
G
Y
-
S
E
F
M
-----
A
S
L
F
-----
G
K
N
W
N
V
A
L
G
Y
P
V
S
A
T
F
N
I
M
A
---
L
I
A
V
F
G
I
A
Y
R
L
G
E
Y
Y
K
VD
A
L
A
S
G
A
L
S
L
V
T
F
L
L
A
T
P
F
Q
V
A
Y
I
M
P
G
T
K
-
E
S
I
L
V
D
G
V
I
P
A
A
L
M
G
----
S
Q
G
L
F
V
A
M
I
I
A
I
I
S
T
E
-
I
Y
R
F
L
V
Q
K
KM
I
I
K
M
P
E
T
V
P
P
A
V
T
R
S
F
A
A
L
I
P
G
F
I
V
V
T
V
V
W
I
I
R
L
I
F
E
H
T
T
F
G
S
I
H
N
V
V
G
K
L
L
Q
E
P
L
S
I
L
G
A
S
L
W
G
A
V
I
A
V
I
L
--
V
H
V
L
W
A
C
G
I
H
G
A
T
I
V
G
G
V
M
S
P
I
W
L
S
L
M
D
Q
N
R
I
A
---
F
Q
A
G
Q
D
--------
V
P
N
---------
T
I
T
A
Q
F
F
D
L
W
I
Y
M
G
G
S
G
A
T
L
A
L
V
V
G
M
L
L
---
F
A
R
S
Q
Q
L
K
S
L
G
R
L
S
I
A
P
G
I
F
-
N
I
N
E
M
V
T
F
G
M
P
I
V
M
N
P
-----
L
L
L
I
P
F
I
V
V
P
V
V
L
T
I
V
S
Y
F
A
M
E
-
W
G
L
V
A
R
P
SGA
A
V
T
W
T
T
P
I
L
F
S
-
G
Y
L
G
S
---
G
G
K
I
S
G
V
I
L
Q
-----
L
V
N
F
A
L
A
F
V
I
Y
L
P
F
L
K
I
W
--
D
K
Q
K
------------------------------------------------------------------------------------------------------------------
25
Fugue
79.81
12%
-111
- C1 -
3NZT
12
?
A:
[26-525]
Y
D
F
K
K
I
N
N
L
R
G
I
E
R
E
T
L
R
V
T
DCG
N
L
A
T
S
N
H
P
D
G
L
G
H
K
L
T
N
N
S
I
T
V
D
F
SE
N
L
L
E
L
I
T
K
P
HDS
I
D
K
A
I
G
E
L
Y
Q
L
S
A
F
T
L
D
N
M
H
SDE
I
I
L
N
T
S
M
P
L
S
A
N
D
N
D
I
---
Q
E
A
D
F
G
S
S
N
S
G
R
M
K
R
V
Y
R
K
G
L
S
A
R
Y
G
K
I
M
Q
I
------------------------
I
S
G
I
H
Y
N
F
S
F
D
K
D
L
I
S
----
N
I
A
T
N
K
Q
V
S
I
S
D
I
Y
F
D
V
L
N
N
Y
F
E
F
M
W
L
L
P
Y
L
F
G
-----
A
S
P
I
C
A
K
T
S
V
K
N
-
K
P
D
Y
L
S
--
V
L
D
D
K
F
Y
V
G
E
Y
A
TS
L
R
M
-
S
D
L
G
S
P
A
Q
K
D
-----
L
A
I
S
Y
D
N
V
K
A
Y
V
K
D
L
I
Q
A
T
D
-
D
T
F
A
D
Y
K
R
I
G
L
Y
N
S
Q
G
Q
R
I
Q
L
N
D
------------
G
I
L
Q
I
E
N
----
E
Y
Y
S
A
I
R
P
K
Q
I
A
K
R
G
E
R
P
A
C
A
L
Y
N
R
---
G
V
-
E
Y
V
E
V
R
V
-
L
D
V
D
P
FEPVG
I
S
K
----
D
T
A
L
F
V
E
V
M
L
M
T
C
L
D
K
D
A
K
K
Y
H
K
---
D
I
I
K
Q
A
K
Q
N
L
T
A
V
A
I
Q
G
R
N
P
Q
L
K
L
K
K
L
D
D
D
S
E
I
L
L
K
D
Y
A
L
E
L
F
D
E
I
E
A
V
A
K
K
M
P
K
E
Y
L
D
A
V
---
E
I
Q
K
R
K
V
L
D
I
S
Q
T
-
P
S
A
K
I
I
E
L
A
R
Q
H
G
Y
K
K
F
I
L
D
I
S
R
R
V
S
Q
Q
F
R
S
Y
E
LP
A
A
-
I
V
A
K
L
K
D
-
Q
A
G
Q
S
V
-
A
-
A
E
K
E
L
V
A
N
D
K
-
I
S
-
L
-
D
E
Y
I
N
R
Y
Y
K
S
S
K
G
C
C---------
8
HHSearch
77.72
41%
-70
- C2 -
3BP3
1
PTGCB_ECOLI
A:
[2-81]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
T
S
E
M
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
I
T
R
L
R
V
S
V
A
D
V
S
--
K
V
-
D
Q
A
G
L
K
K
-
L
G
A
A
G
V
-
V
-
V
A
G
S
G
V
Q
A
I
F
-
G
T
-
K
-
S
D
N
L
K
T
E
M
D
E
Y
I
R
N
----------
3
PsiBlast_PDB
76.49
43%
-73
- C2 -
3BP3
1
PTGCB_ECOLI
A:
[4-79]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
M
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
I
T
R
L
R
V
S
V
A
D
V
S
--
K
V
-
D
Q
A
G
L
K
K
-
L
G
A
A
G
V
-
V
-
V
A
G
S
G
V
Q
A
I
F
-
G
T
-
K
-
S
D
N
L
K
T
E
M
D
E
Y
I
------------
1
PsiBlast_PDB
75.57
41%
-67
- C2 -
1O2F
-
PTGCB_ECOLI
B:
[314-388]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
A
A
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
I
T
R
L
R
V
S
V
A
D
V
S
--
K
V
-
D
Q
A
G
L
K
K
-
L
G
A
A
G
V
-
V
-
V
A
G
S
G
V
Q
A
I
F
-
G
T
-
K
-
S
D
N
L
K
T
E
M
D
E
Y
I
------------
4
PsiBlast_PDB
74.89
43%
-87
- C2 -
3BP8
-
PTGCB_ECOLI
C:
[2-74]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
I
T
R
L
R
V
S
V
A
D
V
S
--
K
V
-
D
Q
A
G
L
K
K
-
L
G
A
A
G
V
-
V
-
V
A
G
S
G
V
Q
A
I
F
-
G
T
-
K
-
S
D
N
L
K
T
E
M
D
E
Y
I
------------
9
HHSearch
67.50
40%
-39
- C2 -
1IBA
-
A:
[15-89]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
I
T
R
L
R
V
S
V
A
D
V
S
--
K
V
-
D
Q
A
G
L
K
K
-
L
G
A
A
G
V
-
V
-
V
A
G
S
G
V
Q
A
I
F
-
G
T
-
K
-
S
D
N
L
K
T
E
M
D
E
Y
I
R
-----------
2
PsiBlast_PDB
67.10
41%
-40
- C2 -
1IBA
-
A:
[15-88]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
P
A
L
V
A
A
F
G
G
K
E
N
I
T
N
L
D
A
C
I
T
R
L
R
V
S
V
A
D
V
S
--
K
V
-
D
Q
A
G
L
K
K
-
L
G
A
A
G
V
-
V
-
V
A
G
S
G
V
Q
A
I
F
-
G
T
-
K
-
S
D
N
L
K
T
E
M
D
E
Y
I
------------
19
Fugue
64.70
26%
-42
- C2 -
3IPJ
1
?
A:
[1-95]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
A
N
K
Y
N
K
I
A
N
E
L
I
K
I
I
G
-
E
D
N
I
I
S
I
T
H
C
A
T
R
L
R
V
M
V
K
D
R
E
--
I
I
-
N
D
K
K
V
E
K
V
D
E
V
K
G
V
-
F
-
F
T
S
G
Q
Y
Q
I
I
L
-
G
T
G
I
-
V
N
K
V
Y
A
E
V
E
K
M
G
L
K
TLSKKEQDEL
6
PsiBlast_CBE
62.90
33%
-34
- C2 -
3IPJ
2
?
B:
[18-82]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
D
N
I
I
S
I
T
H
C
A
T
R
L
R
V
M
V
K
D
R
E
--
I
I
N
D
K
K
V
E
K
V
-
D
E
V
K
G
V
-
F
-
F
T
S
G
Q
Y
Q
I
I
L
-
G
T
-
G
I
V
N
K
V
Y
A
E
V
E
K
M
-------------
10
HHSearch
62.33
28%
-46
- C2 -
3IPJ
1
?
A:
[3-84]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
K
Y
N
K
I
A
N
E
L
I
K
I
I
-
G
E
D
N
I
I
S
I
T
H
C
A
T
R
L
R
V
M
V
K
D
R
E
--
I
I
-
N
D
K
K
V
E
K
V
D
E
V
K
G
V
-
F
-
F
T
S
G
Q
Y
Q
I
I
L
-
G
T
-
G
I
V
N
K
V
Y
A
E
V
E
K
M
G
L
-----------
5
PsiBlast_PDB
61.32
33%
-21
- C2 -
3IPJ
1
?
A:
[18-82]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
D
N
I
I
S
I
T
H
C
A
T
R
L
R
V
M
V
K
D
R
E
--
I
I
N
D
K
K
V
E
K
V
-
D
E
V
K
G
V
-
F
-
F
T
S
G
Q
Y
Q
I
I
L
-
G
T
-
G
I
V
N
K
V
Y
A
E
V
E
K
M
-------------
12
HHSearch
39.99
23%
186
- C2 -
1KKL
-
PTHP_BACSU
H:
[57-94]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
I
M
G
V
M
S
L
G
I
-
A
K
G
A
E
I
T
I
S
A
S
G
A
-
D
-
E
N
D
A
L
N
A
L
E
E
T
M
K
-----------
11
HHSearch
37.42
20%
198
- C2 -
3CCD
1
PTHP_ECOLI
A:
[45-82]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
L
F
K
L
Q
T
L
-
G
L
T
Q
G
T
V
V
T
I
S
A
E
G
E
-
D
-
E
Q
K
A
V
E
H
L
V
K
L
M
A
-----------
16
HHSearch
35.99
22%
143
- C2 -
1PTF
-
PTHP_ENTFA
A:
[40-82]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
--
S
V
-
N
L
K
S
I
---
M
G
V
M
S
L
-
G
V
G
Q
G
S
D
V
T
I
T
V
D
G
A
-
D
-
E
A
E
G
M
A
A
I
V
E
T
L
Q
-----------
14
HHSearch
34.01
19%
157
- C2 -
3LE1
2
?
A:
[44-82]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
S
I
M
G
I
M
S
L
-
G
V
S
Q
G
N
V
V
K
L
S
A
E
G
D
-
D
-
E
E
E
A
I
K
A
L
V
D
L
I
E
-----------
23
Fugue
32.66
32%
303
- C2 -
1L4A
-
CPLX_DORPE
E:
[49-76]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
---
R
K
E
K
H
R
K
M
E
E
E
R
E
E
M
R
Q
T
I
R
D
K
Y
G
L
K
-----------------------------------------------------------------------------------
13
HHSearch
31.00
12%
150
- C2 -
1Y51
-
PTHP_GEOSE
A:
[40-82]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
--
T
V
-
N
L
K
S
I
M
G
-
V
M
S
L
G
I
---
P
K
G
A
T
I
K
I
T
A
E
G
A
-
D
-
A
A
E
A
M
A
A
L
T
D
T
L
A
-----------
26
Fugue
29.04
14%
266
- C2 -
1Y04
-
ANP3_MYOSC
A:
[1-35]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
--
S
M
N
A
P
A
---
R
A
A
A
K
T
A
A
D
A
L
A
A
A
K
K
T
A
A
D
A
A
A
A
A
A
A
A
---------------------------------------------------------------------------------
22
Fugue
28.79
16%
328
- C2 -
1B9P
-
A:
[1-34]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
A
V
--
E
L
R
S
P
G
I
S
R
F
R
R
K
I
A
K
R
S
I
K
T
L
E
H
K
R
E
N
A
K
E
---------------------------------------------------------------------------------------