@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0250: (2016-03-13 )
MLSLTMLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170....----...180.......190-.........200...-....210.......220.......230.-......240..-.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......-----360.......370.....----..380.......390.......400...-------------------------.-----------------------------...410.......420-----......-----.430------........440.......450..---..---...460-......---...470.---.----.....480.......490--------...-------.--------...500-..--.---------....510.......520-.-------...------------------------...530....-------.-------------..540.......550-.......560....--.-..570.......580..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
L
S
L
T
M
L
L
L
E
R
V
G
L
I
I
I
L
A
Y
V
LMN
I
P
Y
F
K
N
L
M
N
R
R
R
T
W
K
A
R
W
Q
L
C
I
I
F
S
L
F
A
L
M
SNL
T
G
I
V
I
DHQHSLS
G
S
V
Y
F
R
LDDDVSLAN
T
R
V
L
T
I
G
V
A
GLVG
G
P
F
V
G
L
F
V
G
V
I
S
G
I
F
R
V
Y
MGGAD
A
Q
V
Y
L
I
S
S
I
F
I
G
I
I
A
G
Y
FG
L
Q
A
Q
R
R
KRY
P
S
I
A
K
S
A
M
I
G
I
V
M
E
M
I
Q
M
L
S
I
L
TFSHD
K
----
A
Y
A
V
D
L
I
S
L
I
A
L
P
M
---
I
I
V
N
S
V
G
T
A
I
F
M
S
I
I
-
I
S
T
L
K
Q
E
E
Q
M
K
A
V
Q
T
H
D
V
L
Q
L
M
N
Q
T
L
P
Y
-
F
K
EGL
N
R
--
E
S
-
A
Q
Q
I
A
M
I
I
K
N
L
M
K
V
S
A
V
A
IT
S
K
N
E
I
L
S
HVGAGSDHHI
P
T
N
E
I
L
T
S
L
S
K
D
V
L
KSGKLKEVHTKEEIGCSHPNCP
L
R
A
A
I
V
I
P
L
EMHG
S
I
V
G
T
L
K
M
Y
F
TNP
N
D
L
T
F
V
E
R
Q
L
A
E
G
L
A
N
I
F
-----
S
S
Q
IELGE
A
E
T
Q
S
K
L
L
K
D
----
A
E
I
K
S
L
Q
A
QVS
P
H
F
F
FN
S
I
N
T
I
S
A
L
V
RI-------------------------
N
-----------------------------
S
E
K
A
R
E
L
L
L
E
L
S
Y
F
F
R-----ANLQGS-----K
Q
H
-------
T
I
T
L
D
K
E
L
S
Q
V
R
A
Y
L
S
L
E
QARYP---
G
R
---
F
N
I
N
---
I
N
V
EDK---YRDVLV
P
---
P
----
F
L
I
Q
I
L
V
E
N
A
I
K
H
A
FTNR--------KQG-------N--------DI
D
V
S
V
-
I
K--E---------TA
T
H
V
R
I
I
V
QDNGQGIS-K-------
D
K
M
------------------------
H
L
LGETSVES-------E-------------SGTG
S
A
L
EN
L
N
L
R
L
K
-
G
LFGK
S
A
A
L
Q
F
EST--S-SG
T
T
F
W
C
VLPYERQEEE
31
HHSearch
79.47
17%
-70
- C4 -
1ID0
2
A:
[2-146]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
-------
L
H
P
V
A
P
L
L
D
N
L
T
S
A
L
N
K
V
Y
Q
R
-----
K
G
---
V
N
I
S
---
L
D
I
S
P
E
---
I
-
S
F
V
G
E
---
Q
N
D
F
V
E
V
M
G
N
V
L
D
N
A
C
K
Y
C
------------
L
E
-----------------
F
V
E
I
S
A
-
R
Q
--
T
----------
D
E
H
L
Y
I
V
V
E
D
D
G
P
G
I
P
-
L
-------
S
K
R
------------------------
E
V
I
F
D
R
G
Q
R
V
DTL----
R
-------------
P
G
Q
G
V
G
L
A
V
A
R
E
I
T
E
-
Q
Y
E
G
K
---
I
V
A
G
E
S
M-
L
-
G
G
A
R
M
E
V
I
F
G
R
Q
H
----
36
HHSearch
78.82
28%
-56
* C4 *
1I58
3
CHEA_THEMA
A:
[50-188]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
P
L
L
H
L
L
R
N
A
I
D
H
G
I
E
P
K
E
E
R
I
A
K
GK
P
P
I
-------
G
--------
T
L
I
L
S
A
-
R
H
--
E
----------
G
N
N
V
V
I
E
V
E
D
D
G
R
G
I
D
-
K
-------
E
K
I
I
R
K
A
I
E
K
GLID
E
S
K
A
A
T
LS
D
Q
E
I
L
N
F
L
F
V
P
G
F
S
T
-------
K
E
K
V
S
E
V
-------
S
G
R
G
V
G
M
D
V
V
K
N
V
V
E
-
S
L
N
G
S
---
I
S
I
E
S
E
K-
D
-
K
G
T
K
V
T
I
R
L
P
L
------
34
HHSearch
77.65
22%
-60
- C4 -
3SL2
2
A:
[3-153]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
I
V
R
F
M
S
L
I
I
D
R
F
E
M
T
---
K
E
---
Q
-----
E
F
I
---
R
N
L
P
D
R
---
D
L
Y
V
E
I
D
---
Q
D
K
I
T
Q
V
L
D
N
I
I
S
N
A
L
K
Y
S
------------
P
E
G
-------
G
--------
H
V
T
F
S
I
-
D
V
NE
E
----------
E
E
L
L
Y
I
S
V
K
D
E
G
I
G
I
P
-
K
-------
K
D
V
------------------------
E
K
V
F
D
R
F
Y
R
V
D------
L
-------------
G
G
T
G
L
G
L
A
I
A
K
E
M
V
Q
-
A
H
G
G
D
---
I
W
A
D
S
I
E-
G
-
K
G
T
T
I
T
F
T
L
P
Y
K
E
----
24
HHSearch
77.44
20%
-5
- C- -
2C2A
2
?
A:
[20-250]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
-------------------------
I
Y
N
S
LGELDLSTL
K
E
F
L
E
V
I
I
D
Q
-------
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
-----
L
E
R
K
S
L
Q
I
---
N
R
E
-------
K
V
D
L
C
D
L
V
E
S
A
V
N
A
I
K
E
F
A
S
S
-----
H
N
---
V
N
V
L
---
F
E
S
N
V
P
C--
P
V
E
A
Y
I
D
---
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
K
K
D
A
---------
P
D
-------
K
--------
Y
V
K
V
I
L
-
D
E
--
K
----------
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
-
D
-------
H
A
K
------------------------
D
R
I
F
E
Q
F
Y
R
V
-------
D
---------------
T
G
L
G
L
A
I
T
K
E
I
V
E
-
L
H
G
G
R
---
I
W
V
E
S
E
V
-
G
-
K
G
S
R
F
F
V
W
I
P
K
D
R
A
---
21
HHSearch
75.87
16%
-43
- C4 -
3A0R
1
?
A:
[133-348]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
M
T
A
R
V
A
H
E
I
R
N
P
I
T
I
I
G
G
F
I
M
R
MKKHLDDPETLKKYI
N
I
I
T
N
-----
E
-----------------------------
L
S
R
L
E
T
I
V
K
E
I
L
E
Y
S
K
-----
E
R
-
V
L
------
E
F
T
-------
E
F
N
L
N
E
L
I
R
E
V
Y
V
L
F
E
E
K
I
R
--
K
---
M
N
---
I
D
F
C
---
F
E
T
D
N
E
---
D
L
R
V
E
A
D
---
R
TR
I
K
Q
V
L
I
N
L
V
Q
N
A
I
E
A
T
------------
G
E
N
-------
G
--------
K
I
K
I
T
S
-
E
D
--
M
----------
Y
T
K
V
R
V
S
V
W
N
S
G
P
P
I
P
-
E
-------
E
L
K
------------------------
E
K
I
F
S
P
F
F
T
T
-------------------------
L
G
L
S
I
C
R
K
I
I
E
D
E
H
G
G
K
---
I
W
T
E
N
R
--
E
-
N
G
V
V
F
I
F
E
I
P
K
T
P
E
K
--
28
HHSearch
75.71
22%
-56
- C4 -
1B3Q
-
CHEA_THEMA
A:
[62-250]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
-------
M
V
P
I
S
F
V
F
N
R
F
P
R
M
V
R
D
L
A
K
K
M
N
---
K
E
---
V
N
F
I
---
M
R
G
E
D
T
---
E
L
D
R
T
F
V
E
E
I
G
----
E
P
L
L
H
L
L
R
N
A
I
D
H
G
I
E
P
K
E
E
R
I
A
K
GK
P
P
I
-------
G
--------
T
L
I
L
S
A
-
R
H
--
E
----------
G
N
N
V
V
I
E
V
E
D
D
G
R
G
I
D
-
K
-------
E
K
I
I
R
K
A
I
E
KGLIDE
S
K
A
A
T
LS
D
Q
E
I
L
N
F
L
F
V
P
G
F
S
-------------------------
G
V
G
M
D
V
V
K
N
V
V
E
-
S
L
N
G
S
---
M
G
I
E
S
E
K-
D
-
K
G
T
K
V
T
I
R
L
P
L
T
L
A
---
29
HHSearch
75.09
18%
-55
- C4 -
3A0Y
-
?
A:
[607-752]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-------
E
F
N
L
N
E
L
I
R
E
V
Y
V
L
F
E
E
K
I
R
--
K
---
M
N
---
I
D
F
C
---
F
E
T
D
N
E
---
D
L
R
V
E
A
D
---
R
T
R
I
K
Q
V
L
I
N
L
V
Q
N
A
I
E
A
T
------------
G
E
N
-------
G
--------
K
I
K
I
T
S
-
E
D
--
M
----------
Y
T
K
V
R
V
S
V
W
N
S
G
P
P
I
P
-
E
-------
E
L
K
------------------------
E
K
I
F
S
P
F
F
T
T
-------
K
--------------
G
T
G
L
G
L
S
I
C
R
K
I
I
E
D
E
H
G
G
K
---
I
W
T
E
N
R
--
E
-
N
G
V
V
F
I
F
E
I
P
K
T
P
----
17
Fugue
71.21
16%
-47
- C2 -
2BBD
8
?
A:
[1-323]
------------------------------------------------------------------------------------------------------------------------------
G
E
I
Y
T
E
T
L
Q
Q
T
Y
A
W
T
A
G
T
N
I
P
I
K
I
P
R
N
N
F
I
R
K
I
R
V
Q
L
I
G
S
I
S
N
S
G
T
A
A
V
T
L
P
SA
P
F
P
Y
N
L
V
Q
T
F
N
L
S
Y
EGS
K
T
L
Y
S
V
S
-
G
T
G
L
G
I
L
M
Y
Y
T
T
K
G
Q
N
P
A
Y
P
A
P
G
T
S
V
P
A
S
G
S
V
N
L
N
V
M
W
E
F
D
L
A
R
FP
A
T
M
V
Q
N
I
I
L
S
I
L
T
G
Q
A
P
S
G
V
S
I
N
A
S
F
Y
I
T
I
T
Y
E
R
V
T
A
Q
E
I
L
S
E
G
G
L
G
A
D
G
E
M
-
P
L
A
T
V
L
P
K
V
I
E
I
P
T
F
N
V
P
A
S
S
A
P
I
H
V
A
Y
L
Q
P
----
G
Q
I
Y
K
R
Q
L
V
Y
V
I
N
S
T
S
----------
G
I
N
N
T
D
-----
P
T
E
Y
E
L
K
I
V
R
G
V
P
T
D
K
I
K
----
V
S
W
A
A
L
Q
A
E
N
Q
A
E
Y
Q
V
A
P
Y
S
G
A
S
A
I
I
D
F
-------------------------
R
-----------------------------
K
Y
F
N
G
D
L
D
L
T
H
A
P
-----------
S
D
S
-----
I
E
Y
-------
D
L
A
L
Q
N
Q
D
N
V
Y
S
L
Y
V
S
Y
V
L
P
Y
Y
D
---
Q
L
---
A
A
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
69.59
17%
-62
- C4 -
1YSR
3
PRRB_MYCTU
A:
[6-149]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-------
P
V
D
I
T
D
L
L
D
R
A
A
H
D
A
A
R
I
Y
-------
P
D
---
L
D
V
S
---
L
V
P
S
P
T
----
C
I
I
V
G
L
---
P
A
G
L
R
L
A
V
D
N
A
I
A
N
A
V
K
H
G
-------------
G
A
-------
T
--------
L
V
Q
L
S
A
-
V
S
--
S
----------
R
A
G
V
E
I
A
I
D
D
N
G
S
G
V
P
-
E
-------
G
E
R
------------------------
Q
V
V
F
E
R
F
S
---------------------------
L
G
L
A
L
V
A
Q
Q
A
Q
-
L
H
G
G
T
---
A
S
L
E
N
S
P-
L
-
G
G
A
R
L
V
L
R
L
P
G
P
-----
18
Fugue
66.46
20%
-54
- C4 -
3EHG
11
A:
[1-125]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
R
L
K
D
E
L
I
N
I
K
Q
I
L
E
A
A
D
I
M
F
I
---
Y
E
---
E
E
K
W
---
P
E
N
I
S
L
---
L
N
E
N
I
L
S
---
M
-----
C
L
K
E
A
V
T
N
V
V
K
H
S
-------------
Q
A
-------
K
--------
T
C
R
V
D
I
-
Q
Q
--
L
----------
W
K
E
V
V
I
T
V
S
D
D
G
T
F
K
G
-
E
------------------------------------------
E
N
-------
S
-------------
F
S
K
G
H
G
L
L
G
M
R
E
R
L
E
-
F
A
N
G
---
S
L
H
I
D
T
---
E
-
N
G
T
K
L
T
M
A
I
P
N
------
22
HHSearch
64.47
16%
-35
- C4 -
2E0A
2
PDK4_HUMAN
A:
[94-353]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
L
S
D
F
V
D
T
L
I
K
V
R
N
R
H
H
N
V
V
P
T
M
A
Q
G
-------------------------
I
I
E
Y
K
D
A
C
T
V
D
PVTN
Q
N
L
Q
Y
F
L
D
R
F
Y
M
N
R
I
S
T
R
M
L
-
M
N
Q
H
I
L
I
F
S
D
-----
S
Q
T
G
N
P
SHIGS
I
D
P
-------
N
C
D
V
V
A
V
V
Q
D
A
F
E
C
S
R
M
L
C
D
Q
Y
Y
L
S
S
P
E
L
K
L
T
Q
V
N
---
G
K
F
P
D
Q
---
P
I
H
I
V
Y
V
---
P
S
H
L
H
H
M
L
F
E
L
F
K
N
A
M
R
A
T
------------
V
E
H
-------
Q
E
NQP
S
L
T
-
P
I
E
V
I
V
-
V
L
--
G
----------
K
E
D
L
T
I
K
I
S
D
R
G
G
G
V
P
-
L
-------
R
I
I
------------------------
D
R
L
F
S
Y
T
Y
S
T
APTPNAP
L
-------------
A
G
F
G
Y
G
L
P
I
S
R
L
Y
A
K
-
Y
F
Q
G
D
---
L
N
L
Y
S
L
S-
G
-
Y
G
T
D
A
I
I
Y
L
K
A
L
S
S
E
--
12
Fugue
63.80
19%
-31
- C4 -
1L0O
2
SP2AB_GEOSE
A:
[1-141]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
N
E
M
H
L
Q
F
S
A
R
S
E
N
E
S
F
---
A
R
---
V
T
V
A
---
A
F
V
A
Q
L
DPT
M
D
E
L
T
E
I
---
K
----
T
V
V
S
E
A
V
T
N
A
I
I
H
G
Y
N
N
D
--------
P
N
G
-------
I
---------
V
S
I
S
V
-
I
I
--
E
----------
D
G
V
V
H
L
T
V
R
D
E
G
V
G
I
P
D
I
-------
E
E
A
------------------------
R
Q
P
L
F
T
T
K
P
E
-------
L
-------------
E
R
S
G
M
G
F
T
I
M
E
N
F
M
D
-
E
V
-------
I
V
E
S
E
--
V
N
K
G
T
T
V
Y
L
K
K
H
I
V
K
S
---
25
HHSearch
63.26
16%
-46
- C4 -
2Q8G
1
PDK1_HUMAN
A:
[107-369]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
D
F
T
D
T
V
I
R
I
R
N
R
H
N
D
V
I
P
T
M
A
Q
G
V
I
E
Y
K
E
S
FDPVT
S
Q
N
V
Q
Y
F
L
D
R
F
Y
M
S
-----------------------------
R
I
S
I
R
M
L
L
N
Q
H
S
L
L
F
G
------------------
K
HIGSINP
N
C
N
V
L
E
V
I
K
D
G
Y
E
N
A
R
R
L
C
D
L
Y
Y
I
N
S
P
E
---
L
E
L
E
E
L
N
A
K
S
P
G
Q
---
P
I
Q
V
V
Y
V
---
P
S
H
L
Y
H
M
V
F
E
L
F
K
N
A
M
R
A
T
------------
M
E
H
H
ANRG
V
Y
P
--------
P
I
Q
V
H
V
-
T
L
--
G
----------
N
E
D
L
T
V
K
M
S
D
R
G
G
G
V
P
-
L
-------
R
K
I
------------------------
D
R
L
F
N
Y
M
Y
S
T
-------
A
PRPRVETSRAVPL
A
G
F
G
Y
G
L
P
I
S
R
L
Y
A
Q
-
Y
F
Q
G
D
---
L
K
L
Y
S
L
E-
G
-
Y
G
T
D
A
V
I
Y
I
K
A
L
S
T
D
--
27
HHSearch
63.05
17%
-54
- C4 -
3JZ3
-
QSEC_ECOLI
A:
[40-216]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A
L
L
Q
L
H-------------------
G
-----------------------------
I
D
R
A
T
R
L
V
D
Q
L
L
T
L
S
R
-----
L
D
S
L
D
N
LQ---
D
V
A
-------
E
I
P
L
E
D
L
L
Q
S
S
V
M
D
I
Y
H
T
A
Q
--
Q
---
A
K
---
I
D
V
R
---
L
T
L
N
A
H
---
S
I
K
R
T
G
Q
---
P
L
L
L
S
L
L
V
R
N
L
L
D
N
A
V
R
Y
S
------------
P
Q
G
-------
S
--------
V
V
D
V
T
L
-
N
A
--
D
--------------
N
F
I
V
R
D
N
G
P
--------------------------------------------------------------------------
L
G
L
S
I
V
Q
R
I
A
K
-
L
H
G
M
N
---
V
E
F
G
N
A
E-
Q
-
G
G
F
E
A
K
V
S
W
L
E
------
3
PsiBlast_PDB
61.98
25%
-24
- C4 -
3SL2
2
A:
[44-153]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
Q
V
L
D
N
I
I
S
N
A
L
K
Y
S
--------
P
E
G
-------
G
--------
H
V
T
F
S
I
D
V
N
--
E
---------
E
E
E
L
L
Y
I
S
V
K
D
E
G
I
G
I
P
-
K
KDVEKVF
D
R
F
------------------------
Y
R
V
D
-------------
L
-------------
G
G
T
G
L
G
L
A
I
A
K
E
M
V
Q
-
A
H
G
G
D
I
W
A
D
S
I
E
G
-----
K
G
T
T
I
T
F
T
L
P
Y
K
E
----
11
PsiBlast_PDB
61.45
30%
18
- C4 -
4Q20
-
DIVL_CAUCR
A:
[163-257]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
E
N
A
L
R
Q
T
------------
P
P
G
-------
G
--------
R
V
T
L
S
A
--
R
--
R
---------
A
L
G
E
V
R
L
D
V
S
D
T
G
R
G
V
P
F
H
-------
V
Q
A
------------------------
H
I
F
D
R
F
V
G
R
D
-------
R
-------------
G
G
P
G
L
G
L
A
-
L
V
K
A
L
V
-
E
L
H
G
G
W
V
A
L
E
S
E
P
---
G
-
N
G
S
T
F
T
C
H
L
P
E
T
Q
----
30
HHSearch
60.74
24%
-45
- C4 -
3EHH
2
DESK_BACSU
A:
[133-215]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
C
L
K
E
A
V
T
N
V
V
K
H
S
-------------
Q
A
-------
K
--------
T
C
R
V
D
I
-
Q
Q
--
L
----------
W
K
E
V
V
I
T
V
S
D
D
G
T
F
K
G
-----------------------------------------------------------------------
H
G
L
L
G
M
R
E
R
L
E
-
F
A
N
G
S
---
L
H
I
D
T
E
----
N
G
T
K
L
T
M
A
I
P
N
------
15
Fugue
58.94
9%
-25
- C4 -
1GKZ
8
BCKD_RAT
A:
[38-378]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
L
T
P
T
M
M
L
Y
S
G
R
S
Q
D
G
S
H
L
L
K
S
G
R
Y
L
Q
Q
E
L
P
V
R
I
A
H
R
I
K
G
F
R
S
L
P
F
I
I
G
C
N
P
T
I
L
H
V
H
E
L
Y
I
R
A
F
Q
K
L
T
D
FPPI
K
D
Q
A
D
E
A
Q
Y
C
Q
L
V
R
Q
L
L
D
D
H
K
D
V
V
T
L
L
A
E
G
L
R
E
S
R
K
H
I
E
D
E
K
L
V
R
Y
F
L
D
K
-------------------------
T
-----------------------------
L
T
S
R
L
G
I
R
M
L
A
T
H
H
L
A
L
HEDK
P
D
F
V
G
I
-----
I
C
T
-------
R
L
S
P
K
K
I
I
E
K
W
V
D
F
A
R
R
L
C
E
H
K
Y
---
G
N
---
A
P
R
V
---
R
I
N
G
H
V
---
A
A
R
F
P
F
I
---
P
----
M
P
L
D
Y
I
L
P
E
L
L
K
N
A
M
R
A
T
--------
M
E
S
-------
H
LDTPY
N
V
P
D
V
V
I
T
I
-
A
N
--
N
---------
D
-
V
D
L
I
I
R
I
S
D
R
G
G
G
I
A
-
H
-------
K
D
L
------------------------
D
R
V
M
D
Y
H
F
T
T
-------
A
-------------
P
M
H
G
F
G
F
-
G
L
P
T
S
R
A
-
Y
A
E
Y
L
G
G
S
L
Q
L
Q
S
L
--
Q
G
I
G
T
D
V
Y
L
R
L
R
H
I
D
G
R
E
E
37
HHSearch
57.85
27%
-39
- C4 -
1R62
-
NTRB_ECOLI
A:
[240-348]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
V
L
L
N
I
V
R
N
A
L
Q
A
L
G
-----------
P
E
G
-------
G
--------
E
I
I
L
R
T
-
R
T
--
A
F
QLTLHGER
Y
R
L
A
A
R
I
D
V
E
D
N
G
P
G
I
-----------------------------------------------------------------------
G
L
G
L
S
I
A
R
N
L
I
D
-
Q
H
S
G
K
---
I
E
F
T
S
W
--
P
-
G
H
T
E
F
S
V
Y
L
P
I
R
-----
39
HHSearch
57.55
17%
-9
- C4 -
1MU5
1
TOP6B_SULSH
A:
[35-150]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
T
V
R
E
L
I
E
N
S
L
D
A
T
------------
D
V
H
-------
G
ILP-----
N
I
K
I
T
I
-
D
L
--
I
DD-------
A
R
Q
I
Y
K
V
N
V
V
D
N
G
I
G
I
P
-
P
-------
Q
E
V
------------------------
P
N
A
F
G
R
V
L
Y
S
KYVN
R
Q
T
R
-------------
G
M
Y
G
L
G
V
K
A
A
V
L
Y
S
Q
-
M
H
Q
D
K
--
P
I
E
I
E
T
S
P
V
N
-
S
K
R
I
Y
T
F
K
L
K
I
D
I
N
---