@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0497: (2016-03-16 )
MSAIIEAKKQLVDEIAEVLSNSVSTVIVDYRGLTVAEVTDLRSQLREAGVEYKVYKNTMVRRAAEKAGIEGLDEFLTGPTAIATSSEDAVAAAKVISGFAKDHEALEIKSGVMEGNVITAEEVKTVGSLPSHDGLVSMLLSVLQAPVRNFAYAVKAIGEQKEENAE
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------.........10........20........30-........40..--.....---.----50........60-......-------.-------.-------.70........80....-.-.-..90-......------------------------------..---100.--..--....110.......120.......130..----.....140.....-----------..-----150.......160.....---------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------M
S
A
I
I
E
A
K
K
Q
L
V
D
E
I
A
E
V
L
SNSV
S
T
V
I
V
DYR-GL
T
V
A
E
V
T
D
L
R
S
--
Q
L
R
EA---G----V
E
Y
K
V
Y
K
N
T
M
V
--
R
R
A
A
E
K
-------A-------
G
-------
I
E
G
L
D
E
FLTGP
T
A
IATS-S-
E
-
D
A
V
A
-
A
A
K
V
I
S
------------------------------
G
F
---AKD
H
--
E
A
--
L
E
I
K
SGVMEG
N
V
I
T
A
E
E
V
K
T
VGSLPSH
D
G
----
L
V
S
M
L
L
S
V
L
Q
A
P
V
-----------
R
N
-----
F
A
Y
A
V
K
A
IG
E
Q
-
K
EENAE---------------------------------------------------------------------------
1
PsiBlast_PDB
99.04
38%
-103
- C3 -
1ZAV
-
RL10_THEMA
A:
[5-177]
---------------------------------------------------------------------------------------
Q
Q
K
E
L
I
V
K
E
M
S
E
I
F
K
K
T
S
L
I
L
F
A
D
F
L
-
G
F
T
V
A
D
L
T
E
L
R
S
--
R
L
R
E
K
YGD
G
----
A
R
F
R
V
V
K
N
T
L
L
--
N
L
A
L
K
N
-------
A
-------
E
-------
Y
E
G
Y
E
E
F
L
K
G
P
T
A
V
L
Y
V
-
T
-
E
G
D
P
V
E
-
A
V
K
I
I
Y
------------------------------
N
F
---
Y
K
D
K
--
K
A
DL
S
R
L
K
G
G
F
L
E
G
K
K
F
T
A
E
E
V
E
N
I
A
K
L
P
S
K
E
E
----
L
Y
A
M
L
V
G
R
V
K
A
P
I
T
G
L
V
F
A
L
S
G
I
L
R
N
-----
L
V
Y
V
L
N
A
I
K
E
K
-
K
--------------------------------------------------------------------------------
22
HHSearch
96.41
38%
-94
- C3 -
1ZAV
-
RL10_THEMA
A:
[2-163]
------------------------------------------------------------------------------------
L
T
R
Q
Q
K
E
L
I
V
K
E
M
S
E
I
F
K
K
T
S
L
I
L
F
A
D
F
L
-
G
F
T
V
A
D
L
T
E
L
R
S
--
R
L
R
E
K
YGD
G
----
A
R
F
R
V
V
K
N
T
L
L
--
N
L
A
L
K
N
-------
A
-------
E
-------
Y
E
G
Y
E
E
F
L
K
G
P
T
A
V
L
Y
V
-
T
E
G
-
D
P
V
E
-
A
V
K
I
I
Y
------------------------------
N
F
---
Y
K
D
K
KA
D
L
--
S
R
L
K
G
G
F
L
E
G
K
K
F
T
A
E
E
V
E
N
I
A
K
L
P
S
K
E
E
----
L
Y
A
M
L
V
G
R
V
K
A
P
I
-----------
T
G
-----
L
V
F
A
L
S
G
I
L
------------------------------------------------------------------------------------
2
PsiBlast_PDB
95.60
38%
-96
- C3 -
1ZAX
-
RL10_THEMA
A:
[5-177]
---------------------------------------------------------------------------------------
Q
Q
K
E
L
I
V
K
E
M
S
E
I
F
K
K
T
S
L
I
L
F
A
D
F
L
-
G
F
T
V
A
D
L
T
E
L
R
S
--
R
L
R
E
K
YGD
G
----
A
R
F
R
V
V
K
N
T
L
L
--
N
L
A
L
K
N
-------
A
-------
E
-------
Y
E
G
Y
E
E
F
L
K
G
P
T
A
V
L
Y
V
-
T
-
E
G
D
P
V
E
-
A
V
K
I
I
Y
------------------------------
N
F
---
Y
K
D
K
--
K
A
DL
S
R
L
K
G
G
F
L
E
G
K
K
F
T
A
E
E
V
E
N
I
A
K
L
P
S
K
E
E
----
L
Y
A
M
L
V
G
R
V
K
A
P
I
T
G
L
V
F
A
L
S
G
I
L
R
N
-----
L
V
Y
V
L
N
A
I
K
E
K
-
K
--------------------------------------------------------------------------------
6
PsiBlast_PDB
74.96
20%
-97
- C3 -
3J7Y
-
RM10_HUMAN
I:
[82-197]
--------------------------------------------------------------------------------------------
L
R
R
E
I
A
A
V
F
Q
D
N
R
M
I
A
V
C
Q
N
V
-
A
L
S
A
E
D
K
L
L
M
R
H
--
Q
L
R
K
H
---
K
----
I
L
M
K
V
F
P
N
Q
V
L
--
K
P
F
L
E
D
-------
S
-------
K
-------
Y
Q
N
L
L
P
L
F
V
G
H
N
M
L
L
V
S
-
E
-
E
-
P
K
V
----
K
E
M
V
------------------------------
R
I
---
L
R
T
V
--
P
F
--
L
P
L
L
G
G
C
I
D
D
T
I
L
S
R
Q
G
F
I
N
Y
S
K
L
-------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
70.15
35%
5
- C3 -
1ZAV
-
RL10_THEMA
A:
[0-177]
----------------------------------------------------------------------------------
V
M
L
T
R
Q
Q
K
E
L
I
V
K
E
M
S
E
I
F
K
K
T
S
L
I
L
F
A
D
F
L
-
G
F
T
V
A
D
L
T
E
L
R
S
--
R
L
R
E
K
YGD
G
----
A
R
F
R
V
V
K
N
T
L
L
--
N
L
A
L
K
N
-------
A
-------
E
-------
Y
E
G
Y
E
E
F
L
K
G
P
T
A
V
L
Y
V
T
E
-
G
-
D
P
V
E
-
A
V
K
I
I
Y
------------------------------
N
F
---
Y
K
D
K
KA
D
L
--
S
R
L
K
G
G
F
L
E
G
K
K
F
T
A
E
E
V
E
N
I
A
K
L
P
S
K
E
E
----
L
Y
A
M
L
V
G
R
V
K
A
P
I
-----------
T
G
-----
L
V
F
A
L
S
G
I
L
R
N
-
L
V
Y
V
L
N
A
I
K
E
K
K---------------------------------------------------------------------
3
PsiBlast_PDB
69.63
37%
5
- C3 -
1ZAW
-
RL10_THEMA
A:
[5-177]
---------------------------------------------------------------------------------------
Q
Q
K
E
L
I
V
K
E
M
S
E
I
F
K
K
T
S
L
I
L
F
A
D
F
L
-
G
F
T
V
A
D
L
T
E
L
R
S
--
R
L
R
E
K
YGD
G
----
A
R
F
R
V
V
K
N
T
L
L
--
N
L
A
L
K
N
-------
A
-------
E
-------
Y
E
G
Y
E
E
F
L
K
G
P
T
A
V
L
Y
V
-
T
-
E
G
D
P
V
E
-
A
V
K
I
I
Y
------------------------------
N
F
---
Y
K
D
K
--
K
A
DL
S
R
L
K
G
G
F
L
E
G
K
K
F
T
A
E
E
V
E
N
I
A
K
L
P
S
K
E
E
----
L
Y
A
M
L
V
G
R
V
K
A
P
I
T
G
L
V
F
A
L
S
G
I
L
R
N
-----
L
V
Y
V
L
N
A
I
K
E
K
-
K
--------------------------------------------------------------------------------
36
Fugue
66.79
15%
-85
- C3 -
3JSY
-
RL10_METJA
A:
[9-221]
-------------------------------------------------------------------------------------
M
A
P
W
K
I
E
E
V
K
T
L
K
G
L
I
K
S
K
P
V
V
A
I
V
D
M
M
-
D
V
P
A
P
Q
L
Q
E
I
R
D
--
K
I
R
D
----
K
----
V
K
L
R
M
S
R
N
T
L
I
--
I
R
A
L
K
E
A
A
E
E
L
NN
P
-------
K
-------
L
A
E
L
A
N
Y
V
E
R
G
A
A
I
L
V
T
-
D
-
M
-
N
P
F
K
-
L
Y
K
L
L
E
E
N
K
S
P
A
P
V
R
GGQIAP
C
D
I
K
V
E
K
G
S
TGMPPG
P
F
---
L
G
E
L
--
K
S
--
V
G
I
P
A
A
I
E
K
G
K
I
A
I
K
E
D
K
V
V
V
K
K
G
E
V
V
S
P
----
K
L
A
A
V
L
D
R
L
G
I
K
P
-----------
I
K
-----
V
G
L
N
I
L
A
V
Y
E
D
-
G
I
I
Y
T
P
D
V
L
K
V
D
EEKLLADI-------------------------------------------------------------
35
Fugue
63.77
18%
-72
- C3 -
3A1Y
-
RL10_PYRHO
G:
[1-284]
----------------------------------------------------------------------------------
M
A
H
V
A
E
W
K
K
K
E
V
E
E
L
A
K
L
I
K
S
Y
P
V
I
A
L
V
D
V
S
-
S
M
P
A
Y
P
L
S
Q
M
R
R
--
L
I
R
E
N
---
G
----
G
L
L
R
V
S
R
N
T
L
I
--
E
L
A
I
K
K
-------
A
AKELGKP
E
-------
L
E
K
L
V
E
Y
I
D
R
G
A
G
I
L
V
T
-
N
-
M
-
N
P
F
K
-
L
Y
K
F
L
Q
------------------------------
Q
N
RQP
Q
P
L
E
--
V
G
--
L
D
V
L
A
V
Y
E
D
G
I
V
Y
T
P
D
V
L
A
I
D
E
Q
E
Y
I
D
M
L
----
Q
K
A
Y
M
H
A
F
N
L
A
V
N
-----------
I
A
YPTPE
T
I
E
A
I
I
Q
K
A
F
L
-
N
A
K
T
V
A
IEAGYITKETIQDIIGRAFRAMLLLAQQLP---------------------------------------------
25
HHSearch
62.53
18%
-84
- C3 -
3JSY
-
RL10_METJA
A:
[10-113]
--------------------------------------------------------------------------------------
A
P
W
K
I
E
E
V
K
T
L
K
G
L
I
K
S
K
P
V
V
A
I
V
D
M
M
-
D
V
P
A
P
Q
L
Q
E
I
R
D
--
K
I
R
D
----
K
----
V
K
L
R
M
S
R
N
T
L
I
--
I
R
A
L
K
E
-------
A
-------
A
E
E
L
NN
P
K
L
A
E
L
A
N
Y
V
E
R
G
A
A
I
L
V
T
-
D
-
M
-
N
P
F
K
-
L
Y
K
L
L
E
------------------------------
E
N
---
K
S
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
54.32
27%
-71
- C3 -
3J16
-
RLA0_YEAST
G:
[1-104]
----------------------------------------------------------------------------------
M
G
G
I
R
E
K
K
A
E
Y
F
A
K
L
R
E
Y
L
E
E
Y
K
S
L
F
V
V
G
V
D
-
N
V
S
S
Q
Q
M
H
E
V
R
K
--
E
L
R
G
R
---
A
----
V
-
V
L
M
G
K
N
T
M
V
--
R
R
A
I
R
G
-------
F
L
S
DLP--
D
-------
F
E
K
L
L
P
F
V
K
G
N
V
G
F
V
F
T
-
N
-
E
-
P
L
T
E
-
I
K
N
V
I
V
------------------------------
S
N
---
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
46.35
17%
-42
* C2 *
1YVE
4
ILV5_SPIOL
I:
[12-236]
-------------------------------------------------------------ATTFDFDSSVFKKEKVTLSGH
D
E
Y
I
V
R
G
G
R
N
L
F
P
L
L
P
D
A
F
K
G
I
K
Q
I
G
V
I
G
W
G
-
S
Q
A
P
A
Q
A
Q
N
L
K
D
--
S
L
T
E
A
---
K
SDVV
V
K
I
G
L
R
K
G
S
N
S
--
F
A
E
A
R
A
-------
A
-------
G
-------
F
S
E
E
N
G
T
L
G
D
M
W
E
T
I
S
G
-
S
-
D
-
L
V
L
L
----
L
I
S
------------------------------
D
S
---
A
Q
A
D
--
N
Y
--
E
K
V
F
S
H
M
K
P
N
S
I
L
G
L
S
H
G
F
L
L
G
H
L
Q
S
L
G
Q
----
D
F
P
K
N
I
S
V
I
A
V
C
P
-----------
K
G
-----
M
G
P
S
V
R
R
L
Y
V
Q
G
K
E
V
N
G
A
GINSSFAVHQDVDGRATDVALGWSIALGSPFTFATT---------------------------------------
16
PsiBlast_PDB
43.71
32%
-45
- C4 -
2F5Z
-
DLDH_HUMAN
A:
[352-422]
------------------------------------------------------------------------------------------------------
N
C
V
P
S
V
I
--
Y
T
-
H
P
E
V
A
W
V
G
K
S
E
E
--
Q
L
K
E
E
---
G
----
I
E
Y
K
V
G
K
F
P
F
A
AN
S
R
A
K
T
N
-------
A
-------
D
-------
T
D
G
M
V
K
I
L
------
G
Q
K
-
S
-
T
-
D
R
V
L
-
G
A
H
I
L
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
43.61
28%
-28
- C3 -
3A1Y
-
RL10_PYRHO
G:
[1-143]
----------------------------------------------------------------------------------
M
A
H
V
A
E
W
K
K
K
E
V
E
E
L
A
K
L
I
K
S
Y
P
V
I
A
L
V
D
V
S
-
S
M
P
A
Y
P
L
S
Q
M
R
R
--
L
I
R
E
N
---
G
----
G
L
L
R
V
S
R
N
T
L
I
--
E
L
A
I
K
K
-------
A
-------
A
-------
K
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
43.27
32%
-45
- C4 -
1ZY8
1
DLDH_HUMAN
A:
[352-422]
------------------------------------------------------------------------------------------------------
N
C
V
P
S
V
I
--
Y
T
-
H
P
E
V
A
W
V
G
K
S
E
E
--
Q
L
K
E
E
---
G
----
I
E
Y
K
V
G
K
F
P
F
A
AN
S
R
A
K
T
N
-------
A
-------
D
-------
T
D
G
M
V
K
I
L
------
G
Q
K
-
S
-
T
-
D
R
V
L
-
G
A
H
I
L
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
42.00
32%
-41
* C4 *
1ZMC
-
DLDH_HUMAN
A:
[352-422]
------------------------------------------------------------------------------------------------------
N
C
V
P
S
V
I
--
Y
T
-
H
P
E
V
A
W
V
G
K
S
E
E
--
Q
L
K
E
E
---
G
----
I
E
Y
K
V
G
K
F
P
F
A
AN
S
R
A
K
T
N
-------
A
-------
D
-------
T
D
G
M
V
K
I
L
------
G
Q
K
-
S
-
T
-
D
R
V
L
-
G
A
H
I
L
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
41.98
32%
-42
- C4 -
1ZMD
-
DLDH_HUMAN
A:
[352-422]
------------------------------------------------------------------------------------------------------
N
C
V
P
S
V
I
--
Y
T
-
H
P
E
V
A
W
V
G
K
S
E
E
--
Q
L
K
E
E
---
G
----
I
E
Y
K
V
G
K
F
P
F
A
AN
S
R
A
K
T
N
-------
A
-------
D
-------
T
D
G
M
V
K
I
L
------
G
Q
K
-
S
-
T
-
D
R
V
L
-
G
A
H
I
L
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
41.83
18%
-47
- C1 -
1UG7
-
AIDA_MOUSE
A:
[1-128]
----------------------------------------------------------------------------------------------
G
S
S
G
S
S
G
M
S
E
V
T
R
S
L
L
Q
R
W
-
G
A
S
L
R
R
G
A
D
F
D
S
W
G
Q
L
V
E
A
---
I
----
D
E
Y
Q
I
L
A
R
H
L
Q
--
K
E
A
Q
A
Q
-------
H
-------
N
-------
N
S
E
F
------------
T
-
E
-
E
-
Q
K
K
T
-
I
G
K
I
A
T
------------------------------
C
L
---
E
L
R
S
--
A
A
--
L
Q
S
T
Q
S
---
Q
E
E
F
K
L
E
D
L
K
K
-------------
L
E
P
I
L
K
N
I
L
T
Y
N
------------
K
E
-----
F
P
F
D
V
Q
P
I
S
G
P
-
S
S
G
------------------------------------------------------------------------------
19
PsiBlast_PDB
41.51
32%
-45
- C4 -
3RNM
2
DLDH_HUMAN
A:
[373-443]
------------------------------------------------------------------------------------------------------
N
C
V
P
S
V
I
--
Y
T
-
H
P
E
V
A
W
V
G
K
S
E
E
--
Q
L
K
E
E
---
G
----
I
E
Y
K
V
G
K
F
P
F
A
AN
S
R
A
K
T
N
-------
A
-------
D
-------
T
D
G
M
V
K
I
L
------
G
Q
K
-
S
-
T
-
D
R
V
L
-
G
A
H
I
L
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
40.64
19%
-24
- C2 -
3VRH
3
?
A:
[1-309]
MKCKFCSREAYIKIHYP
K
M
Y
L
C
E
E
H
F
K
E
Y
F
E
R
K
V
S
R
T
I
E
R
Y
KLLTKDERILVAVSGG
K
D
S
A
V
T
A
Y
V
L
K
K
L
GYN
I
E
C
L
H
I
N
LG
I
S
G
Y
S
E
K
S
E
E
Y
A
K
K
Q
C
K
L
I
G
A
P
L
H
I
V
R
I
K
E
I
L
G
Y
G
I
G
E
V
K
T
R
R
P
--
P
C
S
Y
C
---
G
----
L
----
T
K
R
Y
I
M
--
N
K
F
A
Y
D
-------
N
-------
G
-------
F
D
---------------------------
A
I
A
T
------------------------------
G
H
---
N
L
D
D
--
E
A
--
S
F
L
L
N
N
I
L
H
W
N
---
T
E
Y
L
A
K
G
G
P
I
L
P
Q
Q
G
KF
I
K
K
V
K
P
L
Y
E
V
T
E
R
E
V
-----------
V
A
-----
Y
A
L
A
V
G
L
E
Y
I
V
-
E
E
C
P
Y
T
T
L
D
M
K
G
V
L
N
E
L
E
E
K
RPG
T
K
F
N
F
V
R
G
Y
L
K
K
KKLFEPKECKICRMPSSGDIC
A
F
C
K
F
W
GLK
K
E
I
N
FKVSSTDEEPFG
5
PsiBlast_PDB
39.37
20%
25
- C3 -
4V19
-
?
J:
[82-196]
--------------------------------------------------------------------------------------------
L
R
R
E
I
A
A
V
F
R
D
N
R
M
I
A
V
C
Q
H
V
-
A
L
S
A
E
D
K
L
L
L
R
H
--
Q
L
R
K
H
---
K
----
I
L
M
K
I
F
P
N
Q
V
L
--
K
P
F
L
E
E
-------
S
-------
K
-------
Y
Q
N
L
L
P
L
F
V
G
H
N
L
L
L
V
S
-
E
-
E
-
P
K
V
K
E
M
V
R
I
L
K
------------------------------
G
I
---
P
------
F
--
L
P
L
L
G
G
C
I
D
D
T
I
L
S
R
Q
G
F
I
N
Y
S
K
--------------------------------------------------------------------------------------------------------------------------------------