@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0837: (2016-03-19 )
MIRIQDNTIRDGMQQSNVRKSLIIKKEVLKQINKLNINSVEVGMCTTIEDEFNIHQFRDILSPEKELVVLTRLNEKEIKKIVKLKIHNLVVKILLPISDLHIKEKLNFSNKYYIQKIKDCLDILKKDKKGVDICFEDATRTSREKLKEYMEIISKYQVRTVTFADTVGCSTPLEYGDIFNYFVKKYSNIIFSAHCHNDLGLATANTLAAILNGAKQIETTFLGIGERAGNAPIEEIITILTKKQIESTEFTLPDVYKTSINISKILDFQISENKPIIGENIFKHESGIHQDGTKKNINMYQYLVPSDLGLKNSQVVQFPISNISSKKILHNKFKSIVNTEEIDENISFYKLVNKFSPEVAPEDTVDLLQIIKRRSKDGNFK
Atome Classification :
(26 SA)
--.........10......-..20........30..-.......40......----------.------.------50.-.......60--.-----..--.---....70--...--------...-----..80-------.-----.---.----.....90........100.......110.-------....----..120....-.-.---.130------.--.------.------.-----.----..---140.......150....------...160.......170..-....--.180....-.---.---.-----190.......200.......210.......220....------...230......--.240.---.--------.--.--...250.......260.......270.......280......------------.290..-..--------------------..----.300.-....-...310.-......--320.....----..330........---340.....-..350.......360.......370.......380
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--
M
I
R
IQD
N
T
I
R
D
G
M
Q
Q
S
N
-
V
R
K
S
L
I
I
K
K
E
V
L
K
-
Q
I
-
N
KLNIN
S
V
E
V
G
M
C
T
T----------I------E------DEF-
N
I
H
Q
F
R
D
I
L--S-----PE--K---
E
L
V
V
L
T--RL
N
--------
E
K
E
-----
I
K
K
I
-------
V
-----
K
---
L
----
K
I
H
N
L
V
V
K
I
L
LPISD
L
H
I
K
E
KLNFS
N
K
Y
Y
-------
I
Q
K
I
----
K
D
C
L
D
I
L
K
K-D-K---KG
V
D
------
I
--
C
------F------E-----D----AT---R
T
S
R
E
K
L
K
E
Y
M
E
I
I
S
KY------Q
V
R
T
V
T
F
ADTVGCSTPL
E
-
Y
G
D
I
--
F
N
Y
F
V
K
K
Y
-S---N---
I
-----
I
F
S
A
HCHNDLG
L
A
T
A
N
T
L
A
A
I
LNG
A
K
Q
I
E
T
T
F
L
GIGE------RAGNA
P
I
E
E
I
I
T
--
I
L
T
K
K
---Q--------I--E--STEFTLP
D
V
Y
KTSI
N
I
S
K
I
L
D
F
Q
ISENKPIIG
E
N
I
F
KHESGI------------HQDGTK-KN--------------------
I
N
----
M
Y
-
Q
Y
-LVPS-DLGLKNS-
Q
V
V
Q
F
P--ISNISS
K
K
----
I
L
H
N
-
K
F
K
S
I
V
N
T
---
E
E
I
DEN
I
S
-
F
Y
K
L
V
N
K
FSPEVAPE
D
T
V
D
L
L
Q
I
I
K
RRSKDGNFK
27
Fugue
88.39
29%
-60
- C1 -
4OV4
2
?
A:
[23-408]
P
K
T
I
H
I
Q
D
V
T
L
R
D
G
N
Q
A
L
K
-
R
P
W
T
I
D
E
K
I
E
V
F
D
-
L
L
-
V
E
L
N
V
D
G
I
E
V
G
F
P
S
S
----------
N
------
E
------
T
E
F
-
H
T
C
Q
V
L
S
K
R
--
A
-----
P
K
G-
K
---
P
I
A
A
L
S
--
R
A
N
--------
Q
N
E
-----
I
A
V
T
-------
W
-----
E
---
A
IQ--
K
A
D
C
P
R
M
H
I
V
Y
P
V
S
D
F
S
I
K
H
V
L
K
I
S
E
K
E
V
-------
L
Q
K
I
----
R
N
S
I
S
F
A
R
S
-
I
V
G
---
P
G
I
E
------
I
--
Q
------
F
------
S
-----
G
EHFG
D
A
---
I
E
N
F
A
F
T
K
E
A
F
L
T
A
I
E
A
------
G
A
N
I
I
N
L
P
N
T
V
E
R
Y
R
P
M
V
-
F
V
N
M
--
V
K
E
I
K
D
V
V
-
K
---
D
K--
A
-----
I
I
S
I
H
T
H
N
D
L
G
M
A
T
A
T
S
V
E
S
V
Y
V
G
A
E
Q
I
E
V
A
L
N
G
L
G
E
------
R
A
G
N
T
N
L
Y
E
T
A
I
--
A
L
H
Q
N
---
G
-----------
E
--
N
L
N
I
N
F
Q
R
I
Y
P
T
A
K
R
I
S
E
L
T
G
I
P
I
G
E
K
T
P
I
I
G
E
D
I
F
S
H
R
S
G
I
------------
H
Q
H
Q
S
K
-
G
A
---------------------------
Y
-
R
T
-
F
S
P
E
-
F
V
G
R
M
D
K
-
E
T
I
S
F
T
NQ
S
G
H
K
A
I
E
F
----
L
L
H
Q
-
R
G
I
Q
-
V
S
K
---
E
G
I
H
H
L
F
S
-
L
A
K
S
I
S
S
-
R
E
N
N
R
E
I
T
E
A
E
L
V
A
L
S
Q
---------
35
HHSearch
87.88
30%
-74
- C1 -
3RMJ
4
LEU1_NEIMB
A:
[12-330]
--
R
V
I
I
F
D
T
T
L
R
D
G
E
Q
S
P
G
-
A
A
M
T
K
E
E
K
I
R
V
A
R
-
Q
L
-
E
K
L
G
V
D
I
I
E
A
G
F
A
A
A
----------
S
------
P
------
G
D
F
E
A
V
N
A
I
A
K
T
I
--------
T
K
--
S
---
T
V
C
S
L
S
--
R
A
I
--------
E
R
D
-----
I
R
Q
A
-------
G
-----
E
---
A
V
APA
P
K
K
--
R
I
H
T
F
I
A
T
S
P
I
H
M
E
Y
K
L
K
M
K
P
K
Q
V
-------
I
E
A
A
----
V
K
A
V
K
I
A
R
E
-
Y
-
T
---
D
D
V
E
------
F
--
S
------
C
------
E
-----
D
----
A
L
---
R
S
E
I
D
F
L
A
E
I
C
G
A
V
I
E
A
------
G
A
T
T
I
N
I
P
D
T
V
G
Y
S
I
P
Y
K
-
T
E
E
F
--
F
R
E
L
I
A
K
T
-
P
NGG
K
---
V
-----
V
W
S
A
H
C
H
N
D
L
G
L
A
V
A
N
S
L
A
A
L
K
G
G
A
R
Q
V
E
C
T
V
N
G
L
G
E
------
R
A
G
N
A
S
V
E
E
I
V
M
--
A
L
K
V
R
HDL
F
--------
G
--
L
--
E
T
G
I
D
T
T
Q
I
V
P
S
S
K
L
V
S
T
I
T
G
Y
P
V
Q
P
N
K
A
I
V
G
A
N
A
F
S
-----------------------------------------------
E
----
T
Y
-
E
I
-
M
S
A
E
-
S
V
G
W
A
----------------------------------------------------------------------------------
8
PsiBlast_PDB
85.61
27%
-78
- C1 -
3BLI
3
?
A:
[20-336]
---
L
E
I
L
D
V
T
L
R
D
G
E
Q
T
R
G
-
V
S
F
S
T
S
E
K
L
N
I
A
K
F
L
L
-
Q
K
L
N
V
D
R
V
E
I
A
S
A
R
V
----------
S
------
K
------
G
E
L
E
T
V
Q
K
I
M
E
W
A
--
A
-----
T
E
--
Q
LTE
R
I
E
I
L
G
--
F
V
D
--------
G
N
K
-----
T
V
D
W
-------
I
-----
K
D
S
G
A
----
K
V
L
N
L
L
T
K
G
S
L
H
----
H
L
E
K
Q
L
G
K
T
P
K
E
F
-------
F
T
D
V
----
S
F
V
I
E
Y
A
I
K
-
S
-
G
---
L
K
I
N
------
V
--
Y
------
L
------
E
-----
D
----
W
S
N
G
F
R
N
S
P
D
Y
V
K
S
L
V
E
H
L
S
K
E
------
H
I
E
R
I
F
L
P
D
T
L
G
V
L
S
P
E
E
-
T
F
Q
G
--
V
D
S
L
I
Q
K
Y
-
P
---
D
---
I
-----
H
F
E
F
H
G
H
N
D
Y
D
L
S
V
A
N
S
L
Q
A
I
R
A
G
V
K
G
L
H
A
S
I
N
G
L
G
E
------
R
A
G
N
T
P
L
E
A
L
V
T
--
T
I
H
D
K
---
S
--------
N
--
S
--
K
T
N
I
N
E
I
A
I
T
E
A
S
R
L
V
E
V
F
S
G
K
R
I
S
A
N
R
P
I
V
G
E
D
V
F
T
Q
T
A
G
V
------------------------------------------
N
----
L
Y
-
A
N
P
I
L
P
E
-
R
F
G
R
K
----------------------------------------------------------------------------------
4
PsiBlast_PDB
85.49
31%
-59
- C1 -
4OV9
2
?
A:
[26-370]
---
I
H
I
Q
D
V
T
L
R
D
G
N
Q
A
L
K
-
R
P
W
T
I
D
E
K
I
E
V
F
D
-
L
L
-
V
E
L
N
V
D
G
I
E
V
G
F
P
S
S
----------
N
------
E
------
T
E
F
-
H
T
C
Q
V
L
S
K
R
--
A
-----
P
K
G-
K
---
P
I
A
A
L
S
--
R
A
N
--------
Q
N
E
-----
I
A
V
T
-------
W
-----
E
---
A
I
Q--
K
A
D
C
P
R
M
H
I
V
Y
P
V
S
D
F
S
I
K
H
V
L
K
I
S
E
K
E
V
-------
L
Q
K
I
----
R
N
S
I
S
F
A
R
S
I
V
-
G
---
P
G
I
E
------
I
--
Q
------
F
------
S
GEHFG
D
----
A
I
---
E
N
F
A
F
T
K
E
A
F
L
T
A
I
-
E
A
------
G
A
N
I
I
N
L
P
N
T
V
E
R
Y
R
P
M
-----
V
--
F
V
N
M
V
K
E
I
-
K
---
D
---
V
V
KDK
A
I
I
S
I
H
T
H
N
D
L
G
M
A
T
A
T
S
V
E
S
V
Y
V
G
A
E
Q
I
E
V
A
L
N
G
L
G
E
------
R
A
G
N
T
N
L
Y
E
-
T
A
--
I
A
L
H
Q
---
N
--------
G
--
E
--
N
L
N
I
N
F
Q
R
I
Y
P
T
A
K
R
I
S
E
L
T
G
I
P
I
G
E
K
T
P
I
I
G
E
D
I
F
S
H
R
S
G
I
------------
H
Q
------
T
--------------------
L
H
Q
S
K
G
A
Y
-
R
T
-
F
S
P
E
-
F
V
G
R
M
D
K
-
E
T
I
S
F
----
T
N
Q
S
G
H
K
A
I
E
F
L
L
H
Q
-
R
-----------------------------------------------------
3
PsiBlast_PDB
85.42
31%
-59
- C1 -
4OV4
2
?
A:
[26-370]
---
I
H
I
Q
D
V
T
L
R
D
G
N
Q
A
L
K
-
R
P
W
T
I
D
E
K
I
E
V
F
D
-
L
L
-
V
E
L
N
V
D
G
I
E
V
G
F
P
S
S
----------
N
------
E
------
T
E
F
-
H
T
C
Q
V
L
S
K
R
--
A
-----
P
K
G-
K
---
P
I
A
A
L
S
--
R
A
N
--------
Q
N
E
-----
I
A
V
T
-------
W
-----
E
---
A
IQ--
K
A
D
C
P
R
M
H
I
V
Y
P
V
S
D
F
S
I
K
H
V
L
K
I
S
E
K
E
V
-------
L
Q
K
I
----
R
N
S
I
S
F
A
R
S
I
V
-
G
---
P
G
I
E
------
I
--
Q
------
F
------
S
GEHFG
D
----
A
I
---
E
N
F
A
F
T
K
E
A
F
L
T
A
I
-
E
A
------
G
A
N
I
I
N
L
P
N
T
V
E
R
Y
R
P
M
-----
V
--
F
V
N
M
V
K
E
I
-
K
---
D
---
V
V
KDK
A
I
I
S
I
H
T
H
N
D
L
G
M
A
T
A
T
S
V
E
S
V
Y
V
G
A
E
Q
I
E
V
A
L
N
G
L
G
E
------
R
A
G
N
T
N
L
Y
E
-
T
A
--
I
A
L
H
Q
---
N
--------
G
--
E
--
N
L
N
I
N
F
Q
R
I
Y
P
T
A
K
R
I
S
E
L
T
G
I
P
I
G
E
K
T
P
I
I
G
E
D
I
F
S
H
R
S
G
I
------------
H
Q
----------------------------
H
QSKG
A
Y
-
R
T
-
F
S
P
E
-
F
V
G
R
M
D
K
-
E
T
I
S
F
----
T
N
Q
S
G
H
K
A
I
E
F
L
L
H
Q
-
R
-----------------------------------------------------
6
PsiBlast_PDB
83.95
27%
-77
- C1 -
3BLE
2
?
A:
[20-336]
---
L
E
I
L
D
V
T
L
R
D
G
E
Q
T
R
G
-
V
S
F
S
T
S
E
K
L
N
I
A
K
F
L
L
-
Q
K
L
N
V
D
R
V
E
I
A
S
A
R
V
----------
S
------
K
------
G
E
L
E
T
V
Q
K
I
M
E
W
A
--
A
-----
T
E
--
Q
LTE
R
I
E
I
L
G
--
F
V
D
--------
G
N
K
-----
T
V
D
W
-------
I
-----
K
D
S
G
A
----
K
V
L
N
L
L
T
K
G
S
L
H
----
H
L
E
K
Q
L
G
K
T
P
K
E
F
-------
F
T
D
V
----
S
F
V
I
E
Y
A
I
K
-
S
-
G
---
L
K
I
N
------
V
--
Y
------
L
------
E
-----
D
----
W
S
N
G
F
R
N
S
P
D
Y
V
K
S
L
V
E
H
L
S
K
E
------
H
I
E
R
I
F
L
P
D
T
L
G
V
L
S
P
E
E
-
T
F
Q
G
--
V
D
S
L
I
Q
K
Y
-
P
---
D
---
I
-----
H
F
E
F
H
G
H
N
D
Y
D
L
S
V
A
N
S
L
Q
A
I
R
A
G
V
K
G
L
H
A
S
I
N
G
L
G
E
------
R
A
G
N
T
P
L
E
A
L
V
T
--
T
I
H
D
K
---
S
--------
N
--
S
--
K
T
N
I
N
E
I
A
I
T
E
A
S
R
L
V
E
V
F
S
G
K
R
I
S
A
N
R
P
I
V
G
E
D
V
F
T
Q
----------------------------------------------
N
----
L
Y
-
A
N
P
I
L
P
E
-
R
F
G
R
K
----------------------------------------------------------------------------------
7
PsiBlast_PDB
83.85
27%
-76
- C1 -
3BLF
2
?
A:
[20-336]
---
L
E
I
L
D
V
T
L
R
D
G
E
Q
T
R
G
-
V
S
F
S
T
S
E
K
L
N
I
A
K
F
L
L
-
Q
K
L
N
V
D
R
V
E
I
A
S
A
R
V
----------
S
------
K
------
G
E
L
E
T
V
Q
K
I
M
E
W
A
--
A
-----
T
E
--
Q
LTE
R
I
E
I
L
G
--
F
V
D
--------
G
N
K
-----
T
V
D
W
-------
I
-----
K
D
S
G
A
----
K
V
L
N
L
L
T
K
G
S
L
H
----
H
L
E
K
Q
L
G
K
T
P
K
E
F
-------
F
T
D
V
----
S
F
V
I
E
Y
A
I
K
-
S
-
G
---
L
K
I
N
------
V
--
Y
------
L
------
E
-----
D
----
W
S
N
G
F
R
N
S
P
D
Y
V
K
S
L
V
E
H
L
S
K
E
------
H
I
E
R
I
F
L
P
D
T
L
G
V
L
S
P
E
E
-
T
F
Q
G
--
V
D
S
L
I
Q
K
Y
-
P
---
D
---
I
-----
H
F
E
F
H
G
H
N
D
Y
D
L
S
V
A
N
S
L
Q
A
I
R
A
G
V
K
G
L
H
A
S
I
N
G
L
G
E
------
R
A
G
N
T
P
L
E
A
L
V
T
--
T
I
H
D
K
---
S
--------
N
--
S
--
K
T
N
I
N
E
I
A
I
T
E
A
S
R
L
V
E
V
F
S
G
K
R
I
S
A
N
R
P
I
V
G
E
D
V
F
T
-----------------------------------------------
N
----
L
Y
-
A
N
P
I
L
P
E
-
R
F
G
R
K
----------------------------------------------------------------------------------
1
PsiBlast_PDB
83.67
30%
-62
- C1 -
3RMJ
4
LEU1_NEIMB
A:
[15-330]
-----
I
F
D
T
T
L
R
D
G
E
Q
S
P
G
-
A
A
M
T
K
E
E
K
I
R
V
A
R
-
Q
L
-
E
K
L
G
V
D
I
I
E
A
G
F
A
A
A
----------
S
------
P
------
G
D
F
-
E
A
V
N
A
I
A
K
T
--
I
-----
T
K
--
S
---
T
V
C
S
L
S
--
R
A
I
--------
E
R
D
-----
I
R
Q
A
G
E
A
V
APA
P
-----
K
---
K
----
R
I
H
T
F
I
A
-----
T
S
P
I
H
M
E
Y
K
L
K
M
K
P
K
Q
V
-------
I
E
A
A
----
V
K
A
V
K
I
A
R
E
-
Y
-
T
---
D
D
V
E
------
F
--
S
------
C
------
E
-----
D
----
A
L
---
R
S
E
I
D
F
L
A
E
I
C
G
A
V
I
E
A
------
G
A
T
T
I
N
I
P
D
T
V
G
Y
S
I
P
Y
K
-
T
E
E
F
--
F
R
E
L
I
A
K
T
-
P
---
N
GGK
V
-----
V
W
S
A
H
C
H
N
D
L
G
L
A
V
A
N
S
L
A
A
L
K
G
G
A
R
Q
V
E
C
T
V
N
G
L
G
E
------
R
A
G
N
A
S
V
E
E
I
V
M
--
A
L
K
V
R
---
H
DLFGLETG
I
--
D
--
T
T
Q
-----
I
V
P
S
S
K
L
V
S
T
I
T
G
Y
P
V
Q
P
N
K
A
I
V
G
A
N
A
F
S
-----------------------------------------------
E
----
T
Y
-
E
I
-
M
S
A
E
-
S
V
G
W
A
----------------------------------------------------------------------------------
38
HHSearch
82.02
28%
-67
* C1 *
3BLE
2
?
A:
[19-337]
--
R
L
E
I
L
D
V
T
L
R
D
G
E
Q
T
R
G
-
V
S
F
S
T
S
E
K
L
N
I
A
K
-
F
L
L
Q
K
L
N
V
D
R
V
E
I
A
S
A
R
V
----------
S
------
K
------
G
E
L
E
T
V
Q
K
I
M
E
W
A
--
A
T
E
QLT
E
R
--
I
---
E
I
L
G
F
V
--
D
G
---------
N
K
T
-----
V
D
W
I
-------
K
-----
D
---
S
----
G
A
K
--
V
L
N
L
L
T
K
G
S
L
H
H
L
E
K
Q
L
G
K
T
P
K
E
F
-------
F
T
D
V
----
S
F
V
I
E
Y
A
I
K
-
S
-
G
---
L
K
I
N
------
V
--
Y
------
L
------
E
-----
D
----
W
S
N
G
F
R
N
S
P
D
Y
V
K
S
L
V
E
H
L
S
K
E
------
H
I
E
R
I
F
L
P
D
T
L
G
V
L
S
P
E
E
-
T
F
Q
G
--
V
D
S
L
I
Q
K
Y
-
P
---
D
---
I
-----
H
F
E
F
H
G
H
N
D
Y
D
L
S
V
A
N
S
L
Q
A
I
R
A
G
V
K
G
L
H
A
S
I
N
G
L
G
E
------
R
A
G
N
T
P
L
E
A
L
V
T
--
T
I
H
D
K
---
S
--------
N
--
S
--
K
T
N
I
N
E
I
A
I
T
E
A
S
R
L
V
E
V
F
S
G
K
R
I
S
A
N
R
P
I
V
G
E
D
V
F
T
Q
---------------------------------------------
N
L
----
Y
A
-
N
P
-
I
L
P
E
-
R
F
G
R
K
R
---------------------------------------------------------------------------------
36
HHSearch
81.17
22%
-66
- C1 -
3IVS
2
HOSM_SCHPO
A:
[39-408]
--
N
F
S
I
I
E
S
T
L
R
E
G
E
Q
F
A
N
-
A
F
F
D
T
E
K
K
I
Q
I
A
K
-
A
L
-
D
N
F
G
V
D
Y
I
E
L
T
S
P
V
A
----------
S
------
E
------
Q
S
R
Q
D
C
E
A
I
C
K
L
G
--------
L
K
--
C
---
K
I
L
T
H
I
--
R
C
H
--------
M
D
D
-----
A
R
V
A
-------
V
-----
E
---
T
----
G
V
D
--
G
V
D
V
V
I
G
T
-------------
T
Y
I
-------
I
D
S
A
----
T
E
V
I
N
F
V
K
S
-
K
-
G
---
I
E
V
R
------
F
--
S
------
S
------
E
-----
D
----
S
F
---
R
S
D
L
V
D
L
L
S
L
Y
K
A
V
D
K
I
------
G
V
N
R
V
G
I
A
D
T
V
G
C
A
T
P
R
Q
-
V
Y
D
L
--
I
R
T
L
R
G
V
V
-----
S
---
C
-----
D
I
E
C
H
F
H
N
D
T
G
M
A
I
A
N
A
Y
C
A
L
E
A
G
A
T
H
I
D
T
S
I
L
G
I
G
E
------
R
N
G
I
T
P
L
G
A
L
L
A
--
R
M
Y
V
T
---
D
R
E
------
Y
--
I
--
T
H
K
Y
K
L
N
Q
L
R
E
L
E
N
L
V
A
D
A
V
E
V
Q
I
P
F
N
N
Y
I
T
G
M
C
A
F
T
H
K
A
G
I
------------
H
A
K
A
I
L
-
A
N
--------------------
P
S
----
T
Y
-
E
I
-
L
K
P
E
-
D
F
G
M
S
R
--
Y
V
H
V
G
S
R-
L
T
G
W
N
A
I
K
----
S
R
A
E
-
Q
L
N
L
H
L
------
Q
A
K
E
L
T
V
R
I
K
K
L
A
-
V
R
--
T
L
A
M
D
D
V
D
R
V
L
R
E
Y
H
---------
37
HHSearch
80.19
19%
-62
- C1 -
3HQ1
4
LEU1_MYCTU
A:
[71-523]
--
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
-
D
P
M
S
P
A
R
K
R
R
M
F
D
-
L
L
-
V
R
M
G
Y
K
E
I
E
V
G
F
P
S
A
----------
S
------
Q
------
T
D
F
D
F
V
R
E
I
I
E
Q
G
AI
P
-----
D
D
--
V
---
T
I
Q
V
L
T
--
Q
C
R
--------
P
E
L
-----
I
E
R
T
-------
F
-----
Q
---
A
C
S--
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
-------
Q
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
-
Y
-
P
GTQ
W
R
F
E
------
Y
--
S
------
P
------
E
-----
S
----
Y
T
---
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
I
APTPE
R
P
I
I
F
N
L
P
A
T
V
E
M
T
T
P
N
V
-
Y
A
D
S
--
I
E
W
M
S
R
N
L
-
A
NRE
S
---
V
-----
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
------
R
T
G
N
V
C
L
V
T
L
G
L
--
N
L
F
S
R
---
G
--------
V
-----
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
------------
H
Q
D
A
I
N
-
K
G
L
D
A
M
K
L
D
A
D
A
A
DCDVDDML
W
Q
V
----
P
Y
-
L
P
-
I
D
P
R
-
D
V
G
R
T
Y
E
A
V
I
---------
K
G
G
V
A
----
Y
I
M
K
T
D
H
G
L
S
L
P
R
R
L
Q
I
E
F
S
Q
V
I
Q
K
I
---------
E
V
S
P
K
E
M
W
D
A
F
A
E
-----------
12
PsiBlast_PDB
80.17
25%
-74
- C1 -
3IVS
2
HOSM_SCHPO
A:
[42-350]
-----
I
I
E
S
T
L
R
E
G
E
Q
F
A
N
-
A
F
F
D
T
E
K
K
I
Q
I
A
K
-
A
L
-
D
N
F
G
V
D
Y
I
E
--
L
T
S
P
----------
V
------
A
------
S
E
Q
-
S
R
Q
D
C
E
A
I
C
--
K
-----
L
G
--
L
---
K
C
K
I
L
T
H
I
R
C
H
--------
M
D
D
-----
A
R
V
A
-------
V
-----
E
---
T
----
G
V
D
G
--
V
D
V
V
I
G
T
-------------
T
Y
I
-------
I
D
S
A
----
T
E
V
I
N
F
V
K
S
-------
K
G
I
E
------
V
--
R
------
F
S
S
----
E
-----
D
----
S
F
---
R
S
D
L
V
D
L
L
S
L
Y
K
A
V
D
K
I
------
G
V
N
R
V
G
I
A
D
T
V
G
C
A
T
P
R
Q
-
V
Y
D
L
--
I
R
T
L
R
G
V
V
-
S
---
C
---
D
-----
I
-
E
C
H
F
H
N
D
T
G
M
A
I
A
N
A
Y
C
A
L
E
A
G
A
T
H
I
D
T
S
I
L
G
I
G
E
------
R
N
G
I
T
P
L
G
A
L
L
A
R
M
Y
V
T
D
R
---
E
--------
Y
--
I
--
T
H
K
Y
K
L
N
Q
L
R
E
L
E
N
L
V
A
D
A
V
E
V
Q
I
P
F
N
N
Y
I
T
G
M
C
A
F
T
H
K
A
G
I
------------
H
A
K
A
I
L
-
A
N
--------------------
P
S
----
T
Y
-
E
I
-
L
K
P
E
-
D
F
G
------------------------------------------------------------------------------------
15
PsiBlast_PDB
78.59
27%
-64
- C1 -
2ZYF
2
HOSC_THET2
A:
[5-319]
----
K
I
I
D
S
T
L
R
E
G
E
Q
F
E
K
-
A
N
F
S
T
Q
D
K
V
E
I
A
K
-
A
L
-
D
E
F
G
I
E
Y
I
E
V
---
T
T
----------------------------------
P
V
A
--
S
-----
P
Q
S
R
K
---
D
A
E
V
L
A
--
S
L
G
--------
L
K
-------
A
K
V
-------
V
T
H
I
Q
C
R
---
L
----
D
A
A
K
V
A
V
E
T
G
V
Q
G
I
D
L
-----
L
F
G
T
S
K
--GRDI
P
R
I
I
E
E
A
----
K
E
V
I
A
Y
I
R
E
-
A
-
A
---
P
H
V
E
------
V
--
R
------
F
S
A
----
E
-----
D
----
T
F
---
R
S
E
E
Q
D
L
L
A
V
Y
E
A
V
A
P
Y
-------
V
D
R
V
G
L
A
D
T
V
G
V
A
T
P
R
Q
V
Y
A
L
V
R
E
V
R
R
V
V
G
P
R
-
V
---
D
---
I
-----
E
F
--
H
G
H
N
D
T
G
C
A
I
A
N
A
Y
E
A
I
E
A
G
A
T
H
V
D
T
T
I
L
G
I
G
E
------
R
N
G
I
T
P
L
G
G
F
L
A
--
R
M
Y
T
L
---
Q
--------
P
--
E
Y
V
R
R
K
Y
K
L
E
M
L
P
E
L
D
R
M
V
A
R
M
V
G
V
E
I
P
F
N
N
Y
I
T
G
E
T
A
F
S
H
K
A
G
M
------------
H
L
K
A
I
Y
-
I
N
--------------------
P
E
----
A
Y
-
E
P
-
Y
P
P
E
-
V
F
G
V
K
R
K
-
L
I
I
----------------------------------------------------------------------------
13
PsiBlast_PDB
77.99
27%
-64
- C1 -
2ZTJ
2
HOSC_THET2
A:
[5-319]
----
K
I
I
D
S
T
L
R
E
G
E
Q
F
E
K
-
A
N
F
S
T
Q
D
K
V
E
I
A
K
-
A
L
-
D
E
F
G
I
E
Y
I
E
V
---
T
T
----------------------------------
P
V
A
--
S
-----
P
Q
S
R
K
---
D
A
E
V
L
A
--
S
L
G
--------
L
K
-------
A
K
V
-------
V
T
H
I
Q
C
R
---
L
----
D
A
A
K
V
A
V
E
T
G
V
Q
G
I
D
L
-----
L
F
G
T
----GRD
I
P
R
I
I
E
E
A
----
K
E
V
I
A
Y
I
R
E
-
A
-
A
---
P
H
V
E
------
V
--
R
------
F
S
A
----
E
-----
D
----
T
F
---
R
S
E
E
Q
D
L
L
A
V
Y
E
A
V
A
P
Y
-------
V
D
R
V
G
L
A
D
T
V
G
V
A
T
P
R
Q
V
Y
A
L
V
R
E
V
R
R
V
V
G
P
R
-
V
---
D
---
I
-----
E
F
--
H
G
H
N
D
T
G
C
A
I
A
N
A
Y
E
A
I
E
A
G
A
T
H
V
D
T
T
I
L
G
I
G
E
------
R
N
G
I
T
P
L
G
G
F
L
A
--
R
M
Y
T
L
---
Q
--------
P
--
E
Y
V
R
R
K
Y
K
L
E
M
L
P
E
L
D
R
M
V
A
R
M
V
G
V
E
I
P
F
N
N
Y
I
T
G
E
T
A
F
S
H
K
A
G
M
------------
H
L
K
A
I
Y
-
I
N
--------------------
P
E
----
A
Y
-
E
P
-
Y
P
P
E
-
V
F
G
V
K
R
K
-
L
I
I
----------------------------------------------------------------------------
14
PsiBlast_PDB
77.80
27%
-62
- C1 -
2ZTK
2
HOSC_THET2
A:
[5-319]
----
K
I
I
D
S
T
L
R
E
G
E
Q
F
E
K
-
A
N
F
S
T
Q
D
K
V
E
I
A
K
-
A
L
-
D
E
F
G
I
E
Y
I
E
V
---
T
T
----------------------------------
P
V
A
--
S
-----
P
Q
S
R
K
---
D
A
E
V
L
A
--
S
L
G
--------
L
K
-------
A
K
V
-------
V
T
H
I
Q
C
R
---
L
----
D
A
A
K
V
A
V
E
T
G
V
Q
G
I
D
L
-----
L
F
G
T
----GRD
I
P
R
I
I
E
E
A
----
K
E
V
I
A
Y
I
R
E
-
A
-
A
---
P
H
V
E
------
V
--
R
------
F
S
A
----
E
-----
D
----
T
F
---
R
S
E
E
Q
D
L
L
A
V
Y
E
A
V
A
P
Y
-------
V
D
R
V
G
L
A
D
T
V
G
V
A
T
P
R
Q
V
Y
A
L
V
R
E
V
R
R
V
V
G
P
R
-
V
---
D
---
I
-----
E
F
--
H
G
H
N
D
T
G
C
A
I
A
N
A
Y
E
A
I
E
A
G
A
T
H
V
D
T
T
I
L
G
I
G
E
------
R
N
G
I
T
P
L
G
G
F
L
A
--
R
M
Y
T
L
---
Q
--------
P
--
E
Y
V
R
R
K
Y
K
L
E
M
L
P
E
L
D
R
M
V
A
R
M
V
G
V
E
I
P
F
N
N
Y
I
T
G
E
T
A
F
S
H
K
A
G
M
------------
H
L
K
A
I
Y
-
I
N
--------------------
P
E
----
A
Y
-
E
P
-
Y
P
P
E
-
V
F
G
V
K
R
K
-
L
I
I
----------------------------------------------------------------------------
34
HHSearch
76.56
22%
-68
- C1 -
2ZTJ
2
HOSC_THET2
A:
[3-320]
--
E
W
K
I
I
D
S
T
L
R
E
G
E
Q
F
E
K
-
A
N
F
S
T
Q
D
K
V
E
I
A
K
-
A
L
-
D
E
F
G
I
E
Y
I
E
V
T
T
P
V
A
----------
S
------
P
------
Q
S
R
K
D
A
E
V
L
A
S
L
G
--------
L
K
--
A
---
K
V
V
T
H
I
--
Q
C
R
--------
L
D
A
-----
A
K
V
A
-------
V
-----
E
---
T
----
G
V
Q
--
G
I
D
L
L
F
G
T
---------
G
R
D
I
P
R
I
-------
I
E
E
A
----
K
E
V
I
A
Y
I
R
E
-
A
-
A
PH-
V
E
V
R
------
F
--
S
------
A
------
E
-----
D
----
T
F
---
R
S
E
E
Q
D
L
L
A
V
Y
E
A
V
A
-
P
------
Y
V
D
R
V
G
L
A
D
T
V
G
V
A
T
P
R
Q
-
V
Y
A
L
--
V
R
E
V
R
R
V
V
G
P
---
R
---
V
-----
D
I
E
F
H
G
H
N
D
T
G
C
A
I
A
N
A
Y
E
A
I
E
A
G
A
T
H
V
D
T
T
I
L
G
I
G
E
------
R
N
G
I
T
P
L
G
G
F
L
A
--
R
M
Y
T
L
---
Q
--------
P
E
Y
V
--
R
R
K
Y
K
L
E
M
L
P
E
L
D
R
M
V
A
R
M
V
G
V
E
I
P
F
N
N
Y
I
T
G
E
T
A
F
S
H
K
A
G
M
------------
H
L
K
A
I
Y
-
I
N
--------------------
P
E
----
A
Y
-
E
P
-
Y
P
P
E
-
V
F
G
V
K
R
K
-
L
I
I
A
---------------------------------------------------------------------------
40
HHSearch
73.30
16%
-67
- C1 -
1YDO
1
HMGCL_BACSU
A:
[6-298]
--
K
V
T
I
K
E
V
G
P
R
D
G
L
Q
N
E
P
-
V
W
I
A
T
E
D
K
I
T
W
I
N
-
Q
L
-
S
R
T
G
L
S
Y
I
E
I
T
S
F
V
H
-----------------
P
------
K
W
I
P
A
L
R
D
A
I
D
V
A
--
K
G
IDRE
K
G
--
V
---
T
Y
A
A
L
V
--
P
N
---------
Q
R
G
-----
L
E
N
A
-------
L
-----
E
---
G
----
G
I
N
--
E
A
C
V
F
M
S
A
S
E
T
H
N
R
K
N
I
N
K
S
T
S
E
S
-------
L
H
I
L
----
K
Q
V
N
N
D
A
Q
K
-
A
-
N
---
L
T
T
R
------
A
--
Y
L
S
TVFG
C
------
P
-----
Y
----
E
K
---
D
V
P
I
E
Q
V
I
R
L
S
E
A
L
F
E
F
------
G
I
S
E
L
S
L
G
D
T
I
G
A
A
N
P
A
Q
-
V
E
T
V
--
L
E
A
L
L
A
R
F
-
P
---
A
---
N
-----
Q
I
A
L
H
F
H
D
T
R
G
T
A
L
A
N
M
V
T
A
L
Q
M
G
I
T
V
F
D
G
S
A
G
G
L
G
G
CPYAPG
S
S
G
N
A
A
T
E
D
I
V
Y
--
M
L
E
Q
M
---
D
--------
I
-----
K
T
N
V
K
L
E
K
L
L
S
A
A
K
W
I
E
E
K
M
G
K
P
L
P
S
R
N
L
Q
V
F
K
S
---------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
72.01
17%
-57
- C1 -
2NX9
1
?
A:
[7-356]
--
R
V
G
V
T
D
V
V
L
R
D
A
H
Q
S
L
F
A
T
R
L
R
I
D
D
M
L
P
I
A
Q
-
Q
L
-
D
Q
I
G
Y
W
S
L
E
C
W
G
G
A
T
F
D
S
C
I
R
FLGE
D
------
P
------
W
Q
--
R
L
R
L
L
K
Q
A
M
--------
P
N
--
T
---
P
L
Q
M
L
L
--
R
G
Q
NLLGY
R
H
Y
A
D
D
V
V
D
T
F
V
E
R
A
-------
V
-----
K
---
N
----
G
M
D
--
V
F
R
V
F
D
A
M
N
D
V
R
---------------------
N
M
----
Q
Q
A
L
Q
A
V
K
K
-
M
-
G
---
A
H
A
Q
------
G
T
L
C
------
Y
------
T
-----
T
----
S
P
---
V
H
N
L
Q
T
W
V
D
V
A
Q
Q
L
A
E
L
------
G
V
D
S
I
A
L
K
D
M
A
G
I
L
T
P
Y
A
-
A
E
E
L
--
V
S
T
L
K
K
Q
V
-----
D
---
V
-----
E
L
H
L
H
C
H
S
T
A
G
L
A
D
M
T
L
L
K
A
I
E
A
G
V
D
R
V
D
T
A
I
S
S
M
S
G
------
T
Y
G
H
P
A
T
E
S
L
V
A
--
T
L
Q
G
T
---
G
--------
Y
-----
D
T
G
L
D
I
A
K
L
E
Q
I
A
A
Y
F
R
D
V
R
K
K
Y
H
A
F
E
G
M
M
K
G
S
D
A
R
I
L
V
A
Q
V
P
G
G
M
L
T
N
M
E
S
Q
L
K
Q
Q
N
A
L
D
K
L
--------------------
D
L
----
V
L
E
E
I
-
P
R
V
R
E
E
L
G
F
L
P
----
L
V
T
P
--
T
S
Q
I
V
G
T
Q
----
A
V
I
N
-
V
-----------------------------------------------------
41
HHSearch
71.93
16%
-66
- C1 -
2FTP
3
LIUE_PSEAE
A:
[8-294]
--
K
V
R
L
V
E
V
G
P
R
D
G
L
Q
N
E
K
-
Q
P
I
E
V
A
D
K
I
R
L
V
D
-
D
L
-
S
A
A
G
L
D
Y
I
E
V
G
S
F
V
S
----------
P
------
K
WVPQMA
G
S
A
E
V
F
A
G
I
R
Q
R
---------
P
G
--
V
---
T
Y
A
A
L
A
--
P
N
---------
L
K
G
-----
F
E
A
A
-------
L
-----
E
---
S
----
G
V
K
--
E
V
A
V
F
A
A
A
S
E
A
F
S
Q
R
N
I
N
C
S
I
K
D
S
-------
L
E
R
F
----
V
P
V
L
E
A
A
R
Q
-
H
-
Q
---
V
R
V
R
------
G
--
Y
------
I
S
CVLGC
P
-----
Y
----
D
G
---
D
V
D
P
R
Q
V
A
W
V
A
R
E
L
Q
Q
M
------
G
C
Y
E
V
S
L
G
D
T
I
G
V
G
T
A
G
A
-
T
R
R
L
--
I
E
A
V
A
S
E
V
-
P
---
R
---
E
-----
R
L
A
G
H
F
H
D
T
Y
G
Q
A
L
A
N
I
Y
A
S
L
L
E
G
I
A
V
F
D
S
S
V
A
G
L
G
G
CPYAKG
A
T
G
N
V
A
S
E
D
V
L
Y
--
L
L
N
G
L
---
E
--------
I
-----
H
T
G
V
D
M
H
A
L
V
D
A
G
Q
R
I
C
A
V
L
G
K
S
N
G
S
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
70.48
21%
-64
- C1 -
2CW6
2
HMGCL_HUMAN
A:
[5-291]
--
R
V
K
I
V
E
V
G
P
R
D
G
L
Q
N
E
K
-
N
I
V
S
T
P
V
K
I
K
L
I
D
-
M
L
-
S
E
A
G
L
S
V
I
E
T
T
S
F
V
S
----------
P
KWVPQM
G
------
D
H
T
E
V
L
K
G
I
Q
K
F
---------
P
G
--
I
---
N
Y
P
V
L
T
--
P
N
---------
L
K
G
-----
F
E
A
A
-------
V
-----
A
---
A
----
G
A
K
--
E
V
V
I
F
G
A
A
S
E
L
F
T
K
K
N
I
N
C
S
I
E
E
S
-------
F
Q
R
F
----
D
A
I
L
K
A
A
Q
S
-
A
-
N
---
I
S
V
R
G
Y
V
S
CA
L
--
G
------
C
------
P
-----
Y
----
E
G
---
K
I
S
P
A
K
V
A
E
V
T
K
K
F
Y
S
M
------
G
C
Y
E
I
S
L
G
D
T
I
G
V
G
T
P
G
I
-
M
K
D
M
--
L
S
A
V
M
Q
E
V
-
P
---
L
---
A
-----
A
L
A
V
H
C
H
D
T
Y
G
Q
A
L
A
N
T
L
M
A
L
Q
M
G
V
S
V
V
D
S
S
V
A
G
L
G
G
CPYAQG
A
S
G
N
L
A
T
E
D
L
V
Y
--
M
L
E
G
L
---
G
--------
I
-----
H
T
G
V
N
L
Q
K
L
L
E
A
G
N
F
I
C
Q
A
L
N
R
K
T
S
S
K
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
66.43
31%
-75
- C1 -
3MI3
4
HOSM_SCHPO
A:
[148-347]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
I
-------
I
D
S
A
----
T
E
V
I
N
F
V
K
S
-------
K
G
I
E
------
V
--
R
------
F
S
S
----
E
-----
D
----
S
F
---
R
S
D
L
V
D
L
L
S
L
Y
K
A
V
D
K
I
------
G
V
N
R
V
G
I
A
D
T
V
G
C
A
T
P
R
Q
-
V
Y
D
L
--
I
R
T
L
R
G
V
V
-
S
---
C
---
D
-----
I
-
E
C
H
F
H
N
D
T
G
M
A
I
A
N
A
Y
C
A
L
E
A
G
A
T
H
I
D
T
S
I
L
G
I
G
E
------
R
N
G
I
T
P
L
G
A
L
L
A
R
M
Y
V
T
D
R
---
E
--------
Y
--
I
--
T
H
K
Y
K
L
N
Q
L
R
E
L
E
N
L
V
A
D
A
V
E
V
Q
I
P
F
N
N
Y
I
T
G
M
C
A
F
T
H
K
A
G
I
------------
H
A
K
A
I
L
-
A
N
--------------------
P
S
----
T
Y
-
E
I
-
L
K
P
E
-
D
F
G
M
-----------------------------------------------------------------------------------
21
PsiBlast_CBE
66.36
31%
-76
- C1 -
3MI3
4
HOSM_SCHPO
B:
[148-347]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
I
-------
I
D
S
A
----
T
E
V
I
N
F
V
K
S
-------
K
G
I
E
------
V
--
R
------
F
S
S
----
E
-----
D
----
S
F
---
R
S
D
L
V
D
L
L
S
L
Y
K
A
V
D
K
I
------
G
V
N
R
V
G
I
A
D
T
V
G
C
A
T
P
R
Q
-
V
Y
D
L
--
I
R
T
L
R
G
V
V
-
S
---
C
---
D
-----
I
-
E
C
H
F
H
N
D
T
G
M
A
I
A
N
A
Y
C
A
L
E
A
G
A
T
H
I
D
T
S
I
L
G
I
G
E
------
R
N
G
I
T
P
L
G
A
L
L
A
R
M
Y
V
T
D
R
---
E
--------
Y
--
I
--
T
H
K
Y
K
L
N
Q
L
R
E
L
E
N
L
V
A
D
A
V
E
V
Q
I
P
F
N
N
Y
I
T
G
M
C
A
F
T
H
K
A
G
I
------------
H
A
K
A
I
L
-
A
N
--------------------
P
S
----
T
Y
-
E
I
-
L
K
P
E
-
D
F
G
M
-----------------------------------------------------------------------------------
23
PsiBlast_CBE
65.36
31%
-73
- C1 -
3IVT
3
HOSM_SCHPO
B:
[148-347]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
I
-------
I
D
S
A
----
T
E
V
I
N
F
V
K
S
-------
K
G
I
E
------
V
--
R
------
F
S
S
----
E
-----
D
----
S
F
---
R
S
D
L
V
D
L
L
S
L
Y
K
A
V
D
K
I
------
G
V
N
R
V
G
I
A
D
T
V
G
C
A
T
P
R
Q
-
V
Y
D
L
--
I
R
T
L
R
G
V
V
-
S
---
C
---
D
-----
I
-
E
C
H
F
H
N
D
T
G
M
A
I
A
N
A
Y
C
A
L
E
A
G
A
T
H
I
D
T
S
I
L
G
I
G
E
------
R
N
G
I
T
P
L
G
A
L
L
A
R
M
Y
V
T
D
R
---
E
--------
Y
--
I
--
T
H
K
Y
K
L
N
Q
L
R
E
L
E
N
L
V
A
D
A
V
E
V
Q
I
P
F
N
N
Y
I
T
G
M
C
A
F
T
H
K
A
G
I
------------
H
A
K
A
I
L
-
A
N
--------------------
P
S
----
T
Y
-
E
I
-
L
K
P
E
-
D
F
G
M
-----------------------------------------------------------------------------------
9
PsiBlast_PDB
65.17
31%
-74
- C1 -
3IVT
3
HOSM_SCHPO
A:
[148-347]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
I
-------
I
D
S
A
----
T
E
V
I
N
F
V
K
S
-------
K
G
I
E
------
V
--
R
------
F
S
S
----
E
-----
D
----
S
F
---
R
S
D
L
V
D
L
L
S
L
Y
K
A
V
D
K
I
------
G
V
N
R
V
G
I
A
D
T
V
G
C
A
T
P
R
Q
-
V
Y
D
L
--
I
R
T
L
R
G
V
V
-
S
---
C
---
D
-----
I
-
E
C
H
F
H
N
D
T
G
M
A
I
A
N
A
Y
C
A
L
E
A
G
A
T
H
I
D
T
S
I
L
G
I
G
E
------
R
N
G
I
T
P
L
G
A
L
L
A
R
M
Y
V
T
D
R
---
E
--------
Y
--
I
--
T
H
K
Y
K
L
N
Q
L
R
E
L
E
N
L
V
A
D
A
V
E
V
Q
I
P
F
N
N
Y
I
T
G
M
C
A
F
T
H
K
A
G
I
------------
H
A
K
A
I
L
-
A
N
--------------------
P
S
----
T
Y
-
E
I
-
L
K
P
E
-
D
F
G
M
-----------------------------------------------------------------------------------
22
PsiBlast_CBE
63.40
31%
-74
- C1 -
3IVU
3
HOSM_SCHPO
B:
[148-347]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
I
-------
I
D
S
A
----
T
E
V
I
N
F
V
K
S
-------
K
G
I
E
------
V
--
R
------
F
S
S
----
E
-----
D
----
S
F
---
R
S
D
L
V
D
L
L
S
L
Y
K
A
V
D
K
I
------
G
V
N
R
V
G
I
A
D
T
V
G
C
A
T
P
R
Q
-
V
Y
D
L
--
I
R
T
L
R
G
V
V
-
S
---
C
---
D
-----
I
-
E
C
H
F
H
N
D
T
G
M
A
I
A
N
A
Y
C
A
L
E
A
G
A
T
H
I
D
T
S
I
L
G
I
G
E
------
R
N
G
I
T
P
L
G
A
L
L
A
R
M
Y
V
T
D
R
---
E
--------
Y
--
I
--
T
H
K
Y
K
L
N
Q
L
R
E
L
E
N
L
V
A
D
A
V
E
V
Q
I
P
F
N
N
Y
I
T
G
M
C
A
F
T
H
K
A
G
I
------------
H
A
----------------------------
S
----
T
Y
-
E
I
-
L
K
P
E
-
D
F
G
M
-----------------------------------------------------------------------------------
10
PsiBlast_PDB
63.23
31%
-77
- C1 -
3IVU
3
HOSM_SCHPO
A:
[148-347]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
I
-------
I
D
S
A
----
T
E
V
I
N
F
V
K
S
-------
K
G
I
E
------
V
--
R
------
F
S
S
----
E
-----
D
----
S
F
---
R
S
D
L
V
D
L
L
S
L
Y
K
A
V
D
K
I
------
G
V
N
R
V
G
I
A
D
T
V
G
C
A
T
P
R
Q
-
V
Y
D
L
--
I
R
T
L
R
G
V
V
-
S
---
C
---
D
-----
I
-
E
C
H
F
H
N
D
T
G
M
A
I
A
N
A
Y
C
A
L
E
A
G
A
T
H
I
D
T
S
I
L
G
I
G
E
------
R
N
G
I
T
P
L
G
A
L
L
A
R
M
Y
V
T
D
R
---
E
--------
Y
--
I
--
T
H
K
Y
K
L
N
Q
L
R
E
L
E
N
L
V
A
D
A
V
E
V
Q
I
P
F
N
N
Y
I
T
G
M
C
A
F
T
H
K
A
G
I
------------------------------------------
S
----
T
Y
-
E
I
-
L
K
P
E
-
D
F
G
M
-----------------------------------------------------------------------------------