@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0942: (2016-03-20 )
MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNSQDEEIAKRYGLRSGVGLAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSVQEAYLPTGEGCLSVDDNVAGLVHRHNRITIKAKDIEGNDIQLRLKGYPAIVFQHEIDHLNGVMFYDHIDKNHPLQPHTDAVEV
Atome Classification :
(41 SA)
.........10........20........30........40.....--...50........60........70........--80---....------....--.90........100.......110.......120.......130.......140.......150.......160.......170.......180.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
ML
T
M
K
D
I
I
RDG
H
P
T
L
R
Q
K
A
A
ELELPL
T
K
E
E
K
E
T
L
I
A
M
R
E
F
L
VNSQ
D
--
E
E
I
A
K
RYGLRSGVGLAAP
Q
I
NIS
K
R
M
I
A
V
L
I
PD--D----GSGK------
S
Y
D
Y
--
M
L
VN
P
K
I
V
S
H
S
V
Q
E
AYLPTGE
G
C
L
SVD
D
N
V
A
G
L
V
HRH
N
R
I
T
I
K
A
KDIEGN
D
I
Q
L
R
L
KG
Y
P
A
I
V
F
Q
HEIDHLN
G
V
M
F
Y
DHIDKNHPLQPHTDAVEV
1
PsiBlast_PDB
99.00
100%
-108
- C7 -
1LQW
1
DEF_STAAU
A:
[1-183]
M
L
T
M
K
D
I
I
R
D
G
H
P
T
L
R
Q
K
A
A
E
L
E
L
P
L
T
K
E
E
K
E
T
L
I
A
M
R
E
F
L
V
N
S
Q
D
--
E
E
I
A
K
R
Y
G
L
R
S
G
V
G
L
A
A
P
Q
I
N
I
S
K
R
M
I
A
V
L
I
P
D
--
D
----
G
S
G
K
------
S
Y
D
Y
--
M
L
V
N
P
K
I
V
S
H
S
V
Q
E
A
Y
L
P
T
G
E
G
C
L
S
V
D
D
N
V
A
G
L
V
H
R
H
N
R
I
T
I
K
A
K
D
I
E
G
N
D
I
Q
L
R
L
K
G
Y
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
D
K
N
H
P
L
Q
P
H
T
D
A
V
E
V
21
PsiBlast_CBE
98.12
100%
-104
- C7 -
2AI9
2
DEF_STAAU
B:
[1-183]
M
L
T
M
K
D
I
I
R
D
G
H
P
T
L
R
Q
K
A
A
E
L
E
L
P
L
T
K
E
E
K
E
T
L
I
A
M
R
E
F
L
V
N
S
Q
D
--
E
E
I
A
K
R
Y
G
L
R
S
G
V
G
L
A
A
P
Q
I
N
I
S
K
R
M
I
A
V
L
I
P
D
--
D
----
G
S
G
K
------
S
Y
D
Y
--
M
L
V
N
P
K
I
V
S
H
S
V
Q
E
A
Y
L
P
T
G
E
G
C
L
S
V
D
D
N
V
A
G
L
V
H
R
H
N
R
I
T
I
K
A
K
D
I
E
G
N
D
I
Q
L
R
L
K
G
Y
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
D
K
N
H
P
L
Q
P
H
T
D
A
V
E
V
22
PsiBlast_CBE
98.00
100%
-98
- C7 -
1LQW
1
DEF_STAAU
B:
[1-183]
M
L
T
M
K
D
I
I
R
D
G
H
P
T
L
R
Q
K
A
A
E
L
E
L
P
L
T
K
E
E
K
E
T
L
I
A
M
R
E
F
L
V
N
S
Q
D
--
E
E
I
A
K
R
Y
G
L
R
S
G
V
G
L
A
A
P
Q
I
N
I
S
K
R
M
I
A
V
L
I
P
D
--
D
----
G
S
G
K
------
S
Y
D
Y
--
M
L
V
N
P
K
I
V
S
H
S
V
Q
E
A
Y
L
P
T
G
E
G
C
L
S
V
D
D
N
V
A
G
L
V
H
R
H
N
R
I
T
I
K
A
K
D
I
E
G
N
D
I
Q
L
R
L
K
G
Y
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
D
K
N
H
P
L
Q
P
H
T
D
A
V
E
V
2
PsiBlast_PDB
97.71
100%
-106
- C7 -
2AI9
2
DEF_STAAU
A:
[1-183]
M
L
T
M
K
D
I
I
R
D
G
H
P
T
L
R
Q
K
A
A
E
L
E
L
P
L
T
K
E
E
K
E
T
L
I
A
M
R
E
F
L
V
N
S
Q
D
--
E
E
I
A
K
R
Y
G
L
R
S
G
V
G
L
A
A
P
Q
I
N
I
S
K
R
M
I
A
V
L
I
P
D
--
D
----
G
S
G
K
------
S
Y
D
Y
--
M
L
V
N
P
K
I
V
S
H
S
V
Q
E
A
Y
L
P
T
G
E
G
C
L
S
V
D
D
N
V
A
G
L
V
H
R
H
N
R
I
T
I
K
A
K
D
I
E
G
N
D
I
Q
L
R
L
K
G
Y
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
D
K
N
H
P
L
Q
P
H
T
D
A
V
E
V
3
PsiBlast_PDB
95.54
96%
-101
- C7 -
1LMH
1
DEF_STAAU
A:
[2-183]
-
L
T
M
K
D
I
I
R
D
G
H
P
T
L
R
Q
K
A
A
E
L
E
L
P
L
T
K
E
E
K
E
T
L
I
A
M
R
E
F
L
V
N
S
Q
D
--
E
E
I
A
K
R
Y
G
L
R
S
G
V
G
L
A
A
P
Q
I
N
I
S
K
R
M
I
A
V
L
I
P
D
--
D
----
G
S
G
K
------
S
Y
D
Y
--
M
L
V
N
P
K
I
V
S
H
S
V
Q
E
A
Y
L
P
T
G
E
G
C
L
S
V
D
D
N
V
A
G
L
V
H
R
H
N
K
I
T
I
K
A
K
D
I
E
G
N
D
I
Q
L
R
L
K
G
Y
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
D
K
D
H
P
L
Q
P
H
T
D
A
V
E
V
7
PsiBlast_PDB
84.88
54%
-92
- C7 -
2OS3
2
DEF_STRP1
A:
[12-194]
L
I
T
M
D
D
I
I
R
E
G
N
P
T
L
R
A
V
A
K
E
V
S
L
P
L
C
D
E
D
I
L
L
G
E
K
M
M
Q
F
L
K
H
S
Q
D
--
P
V
M
A
E
K
L
G
L
R
A
G
V
G
L
A
A
P
Q
I
D
V
S
K
R
I
I
A
V
L
V
P
N
L
P
D
----
K
E
G
N
PPKEAY
S
W
Q
E
--
V
L
Y
N
P
K
I
V
S
H
S
V
Q
D
A
A
L
S
D
G
E
G
C
L
S
V
D
R
V
V
E
G
Y
V
V
R
H
A
R
V
T
V
D
Y
Y
D
K
E
G
Q
Q
H
R
I
K
L
K
G
Y
N
A
I
V
V
Q
H
E
I
D
H
I
N
G
V
L
F
Y
D
R
I
N
A
K
N
P
F
E
--------
5
PsiBlast_PDB
84.48
57%
-86
- C7 -
1LQY
3
DEF2_GEOSE
A:
[1-182]
M
I
T
M
K
D
I
I
K
E
G
H
P
T
L
R
K
V
A
E
P
V
P
L
P
P
S
E
E
D
K
R
I
L
Q
S
L
L
D
Y
V
K
M
S
Q
D
--
P
E
L
A
A
K
Y
G
L
R
P
G
I
G
L
A
A
P
Q
I
N
V
S
K
R
M
I
A
V
H
V
T
D
--
E
-----
N
G
T
------
L
Y
S
Y
--
A
L
F
N
P
K
I
V
S
H
S
V
Q
Q
C
Y
L
T
T
G
E
G
C
L
S
V
D
R
D
V
P
G
Y
V
L
R
Y
A
R
I
T
V
T
G
T
T
L
D
G
E
E
V
T
L
R
L
K
G
L
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
I
M
F
Y
D
R
I
N
P
A
D
P
F
Q
V
P
D
G
A
I
P
I
106
HHSearch
82.92
59%
-87
- C7 -
2OKL
5
DEF2_BACCR
A:
[2-182]
M
L
T
M
K
D
V
I
R
E
G
D
P
I
L
R
N
V
A
E
E
V
S
L
P
A
S
E
E
D
T
T
T
L
K
E
M
I
E
F
V
I
N
S
Q
D
--
P
E
M
A
E
K
Y
S
L
R
P
G
I
G
L
A
A
P
Q
I
G
V
S
K
K
M
I
A
V
H
V
T
D
--
A
----
D
-
G
T
------
L
Y
S
H
--
A
L
F
N
P
K
I
I
S
H
S
V
E
R
T
Y
L
Q
G
G
E
G
C
L
S
V
D
R
E
V
P
G
Y
V
P
R
Y
T
R
I
T
V
K
A
T
S
I
N
G
E
E
V
K
L
R
L
K
G
L
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
N
K
E
N
P
F
A
A
P
D
D
S
K
P
-
23
PsiBlast_CBE
82.44
59%
-94
- C7 -
2OKL
4
DEF2_BACCR
B:
[2-180]
M
L
T
M
K
D
V
I
R
E
G
D
P
I
L
R
N
V
A
E
E
V
S
L
P
A
S
E
E
D
T
T
T
L
K
E
M
I
E
F
V
I
N
S
Q
D
--
P
E
M
A
E
K
Y
S
L
R
P
G
I
G
L
A
A
P
Q
I
G
V
S
K
K
M
I
A
V
H
V
-
T
--
D
----
A
D
G
T
------
L
Y
S
H
--
A
L
F
N
P
K
I
I
S
H
S
V
E
R
T
Y
L
Q
G
G
E
G
C
L
S
V
D
R
E
V
P
G
Y
V
P
R
Y
T
R
I
T
V
K
A
T
S
I
N
G
E
E
V
K
L
R
L
K
G
L
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
N
K
E
N
P
F
A
A
P
D
D
S
---
4
PsiBlast_PDB
82.35
59%
-89
- C7 -
2OKL
5
DEF2_BACCR
A:
[2-180]
M
L
T
M
K
D
V
I
R
E
G
D
P
I
L
R
N
V
A
E
E
V
S
L
P
A
S
E
E
D
T
T
T
L
K
E
M
I
E
F
V
I
N
S
Q
D
--
P
E
M
A
E
K
Y
S
L
R
P
G
I
G
L
A
A
P
Q
I
G
V
S
K
K
M
I
A
V
H
V
-
T
--
D
----
A
D
G
T
------
L
Y
S
H
--
A
L
F
N
P
K
I
I
S
H
S
V
E
R
T
Y
L
Q
G
G
E
G
C
L
S
V
D
R
E
V
P
G
Y
V
P
R
Y
T
R
I
T
V
K
A
T
S
I
N
G
E
E
V
K
L
R
L
K
G
L
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
N
K
E
N
P
F
A
A
P
D
D
S
---
6
PsiBlast_PDB
81.95
54%
-101
- C7 -
2OS1
5
DEF_ENTFA
A:
[1-177]
M
I
T
M
K
D
I
I
R
E
G
N
P
T
L
R
A
V
A
E
E
V
P
V
P
I
T
E
E
D
R
Q
L
G
E
D
M
L
T
F
L
K
N
S
Q
D
--
P
V
K
A
E
E
L
Q
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
H
V
P
------------------
S
L
S
T
--
V
M
Y
N
P
K
I
L
S
H
S
V
Q
D
V
C
L
G
E
G
E
G
C
L
S
V
D
R
D
V
P
G
Y
V
V
R
H
N
K
I
T
V
S
Y
F
D
M
A
G
E
K
H
K
V
R
L
K
N
Y
E
A
I
V
V
Q
H
E
I
D
H
I
N
G
I
M
F
Y
D
H
I
N
K
E
N
P
F
---------
10
PsiBlast_PDB
81.66
53%
-102
- C7 -
2OS0
2
DEF_ENTFA
A:
[1-177]
M
I
T
M
K
D
I
I
R
E
G
N
P
T
L
R
A
V
A
E
E
V
P
V
P
I
T
E
E
D
R
Q
L
G
E
D
M
L
T
F
L
K
N
S
Q
D
--
P
V
K
A
E
E
L
Q
L
R
G
D
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
H
V
P
------------------
S
L
S
T
--
V
M
Y
N
P
K
I
L
S
H
S
V
Q
D
V
C
L
G
E
G
E
G
C
L
S
V
D
R
D
V
P
G
Y
V
V
R
H
N
K
I
T
V
S
Y
F
D
M
A
G
E
K
H
K
V
R
L
K
N
Y
E
A
I
V
V
Q
H
E
I
D
H
I
N
G
I
M
F
Y
D
H
I
N
K
E
N
P
F
---------
101
HHSearch
81.56
51%
-94
- C7 -
2OS0
2
DEF_ENTFA
A:
[1-185]
M
I
T
M
K
D
I
I
R
E
G
N
P
T
L
R
A
V
A
E
E
V
P
V
P
I
T
E
E
D
R
Q
L
G
E
D
M
L
T
F
L
--
K
N
S
Q
D
P
V
K
A
E
E
L
Q
L
R
G
D
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
H
V
P
------------------
S
L
S
T
--
V
M
Y
N
P
K
I
L
S
H
S
V
Q
D
V
C
L
G
E
G
E
G
C
L
S
V
D
R
D
V
P
G
Y
V
V
R
H
N
K
I
T
V
S
Y
F
D
M
A
G
E
K
H
K
V
R
L
K
N
Y
E
A
I
V
V
Q
H
E
I
D
H
I
N
G
I
M
F
Y
D
H
I
N
K
E
N
P
F
A
L
K
E
G
V
L
V
-
25
PsiBlast_CBE
81.00
54%
-102
- C7 -
3CMD
7
?
B:
[10-186]
M
I
T
M
D
D
I
I
R
E
G
N
P
T
L
R
E
V
A
K
E
V
S
L
P
L
S
E
E
D
I
S
L
G
K
E
M
L
E
F
L
K
N
S
Q
D
--
P
I
K
A
E
E
L
H
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
H
V
P
S
-----------------
S
L
S
T
--
V
M
Y
N
P
K
I
L
S
H
S
V
Q
D
A
C
L
G
E
G
E
G
C
L
S
V
D
R
E
V
P
G
Y
V
V
R
H
A
K
I
T
V
S
Y
Y
D
M
N
G
E
K
H
K
I
R
L
K
N
Y
E
S
I
V
V
Q
H
E
I
D
H
I
N
G
V
M
F
Y
D
H
I
N
D
Q
N
P
F
---------
8
PsiBlast_PDB
80.82
54%
-104
- C7 -
3G6N
3
?
A:
[5-181]
M
I
T
M
D
D
I
I
R
E
G
N
P
T
L
R
E
V
A
K
E
V
S
L
P
L
S
E
E
D
I
S
L
G
K
E
M
L
E
F
L
K
N
S
Q
D
--
P
I
K
A
E
E
L
H
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
H
V
P
S
-----------------
S
L
S
T
--
V
M
Y
N
P
K
I
L
S
H
S
V
Q
D
A
C
L
G
E
G
E
G
C
L
S
V
D
R
E
V
P
G
Y
V
V
R
H
A
K
I
T
V
S
Y
Y
D
M
N
G
E
K
H
K
I
R
L
K
N
Y
E
S
I
V
V
Q
H
E
I
D
H
I
N
G
V
M
F
Y
D
H
I
N
D
Q
N
P
F
---------
12
PsiBlast_PDB
80.69
51%
-98
- C7 -
2AIE
3
DEF_STRR6
P:
[13-193]
L
I
D
M
C
D
I
I
R
E
G
N
P
S
L
R
T
V
A
E
E
V
T
F
P
L
S
D
Q
E
I
I
L
G
E
K
M
M
Q
F
L
K
H
S
Q
D
--
P
V
M
A
E
K
M
G
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
L
V
P
N
I---------
E
------
A
Y
D
L
EA
I
M
Y
N
P
K
I
V
S
H
S
V
Q
D
A
A
L
G
E
G
E
G
C
L
S
V
D
R
N
V
P
G
Y
V
V
R
H
A
R
V
T
V
D
Y
F
D
K
D
G
E
K
H
R
I
K
L
K
G
Y
N
S
I
V
V
Q
H
E
I
D
H
I
N
G
I
M
F
Y
D
R
I
N
E
K
D
P
F
---------
9
PsiBlast_PDB
80.61
54%
-103
- C7 -
3CMD
6
?
A:
[10-186]
M
I
T
M
D
D
I
I
R
E
G
N
P
T
L
R
E
V
A
K
E
V
S
L
P
L
S
E
E
D
I
S
L
G
K
E
M
L
E
F
L
K
N
S
Q
D
--
P
I
K
A
E
E
L
H
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
H
V
P
S
-----------------
S
L
S
T
--
V
M
Y
N
P
K
I
L
S
H
S
V
Q
D
A
C
L
G
E
G
E
G
C
L
S
V
D
R
E
V
P
G
Y
V
V
R
H
A
K
I
T
V
S
Y
Y
D
M
N
G
E
K
H
K
I
R
L
K
N
Y
E
S
I
V
V
Q
H
E
I
D
H
I
N
G
V
M
F
Y
D
H
I
N
D
Q
N
P
F
---------
24
PsiBlast_CBE
80.38
54%
-103
- C7 -
3G6N
5
?
B:
[5-181]
M
I
T
M
D
D
I
I
R
E
G
N
P
T
L
R
E
V
A
K
E
V
S
L
P
L
S
E
E
D
I
S
L
G
K
E
M
L
E
F
L
K
N
S
Q
D
--
P
I
K
A
E
E
L
H
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
H
V
P
S
-----------------
S
L
S
T
--
V
M
Y
N
P
K
I
L
S
H
S
V
Q
D
A
C
L
G
E
G
E
G
C
L
S
V
D
R
E
V
P
G
Y
V
V
R
H
A
K
I
T
V
S
Y
Y
D
M
N
G
E
K
H
K
I
R
L
K
N
Y
E
S
I
V
V
Q
H
E
I
D
H
I
N
G
V
M
F
Y
D
H
I
N
D
Q
N
P
F
---------
11
PsiBlast_PDB
80.07
51%
-95
- C7 -
3SW8
5
?
P:
[13-193]
L
I
D
M
N
D
I
I
R
E
G
N
P
T
L
R
T
V
A
E
E
V
T
F
P
L
S
D
Q
E
I
I
L
G
E
K
M
M
Q
F
L
K
H
S
Q
D
--
P
V
M
A
E
K
M
G
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
L
V
P
N
I---------
E
------
A
Y
D
L
EA
I
M
Y
N
P
K
I
V
S
H
S
V
Q
D
A
A
L
G
E
G
E
G
C
L
S
V
D
R
N
V
P
G
Y
V
V
R
H
A
R
V
T
V
D
Y
F
D
K
D
G
E
K
H
R
I
K
L
K
G
Y
N
S
I
V
V
Q
H
E
I
D
H
I
N
G
I
M
F
Y
D
R
I
N
E
K
D
P
F
---------
14
PsiBlast_PDB
80.06
51%
-96
- C7 -
2AIA
3
DEF_STRR6
A:
[13-193]
L
I
D
M
C
D
I
I
R
E
G
N
P
S
L
R
T
V
A
E
E
V
T
F
P
L
S
D
Q
E
I
I
L
G
E
K
M
M
Q
F
L
K
H
S
Q
D
--
P
V
M
A
E
K
M
G
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
L
V
P
N
-----------------
A
Y
D
L
E
A
I
M
Y
N
P
K
I
V
S
H
S
V
Q
D
A
A
L
G
E
G
E
G
C
L
S
V
D
R
N
V
P
G
Y
V
V
R
H
A
R
V
T
V
D
Y
F
D
K
D
G
E
K
H
R
I
K
L
K
G
Y
N
S
I
V
V
Q
H
E
I
D
H
I
N
G
I
M
F
Y
D
R
I
N
E
K
D
P
F
---------
13
PsiBlast_PDB
80.01
51%
-94
- C7 -
2AI7
3
DEF_STRR6
A:
[13-193]
L
I
D
M
C
D
I
I
R
E
G
N
P
S
L
R
T
V
A
E
E
V
T
F
P
L
S
D
Q
E
I
I
L
G
E
K
M
M
Q
F
L
K
H
S
Q
D
--
P
V
M
A
E
K
M
G
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
L
V
P
N
I---------
E
------
A
Y
D
L
E
A
I
M
Y
N
P
K
I
V
S
H
S
V
Q
D
A
A
L
G
E
G
E
G
C
L
S
V
D
R
N
V
P
G
Y
V
V
R
H
A
R
V
T
V
D
Y
F
D
K
D
G
E
K
H
R
I
K
L
K
G
Y
N
S
I
V
V
Q
H
E
I
D
H
I
N
G
I
M
F
Y
D
R
I
N
E
K
D
P
F
---------
17
PsiBlast_PDB
63.60
35%
-71
- C7 -
3UWB
4
?
A:
[9-150]
----------
G
D
R
C
L
R
Q
K
S
E
E
V
E
F
--
D
K
K
E
M
S
E
L
Y
-------------
D
Q
M
C
E
A
M
W
A
S
D
G
I
G
L
A
A
P
Q
V
G
I
N
K
R
V
I
V
V
D
E
T
T
--
E
----
E
H
G
K
-------
Y
A
H
--
L
M
V
N
P
K
I
T
W
K
S
E
E
K
V
L
F
D
--
E
G
C
L
S
V
P
D
Q
-
N
G
E
V
L
R
P
K
S
I
K
V
T
F
Q
N
K
D
G
K
Y
K
K
W
K
L
D
G
L
A
A
R
V
V
Q
H
E
I
D
H
L
E
G
I
L
F
V
D
Y
F
N
--------------
39
PsiBlast_CBE
63.34
34%
-48
- C7 -
1SV2
3
DEF_LEPIN
B:
[1-157]
--
S
V
R
K
I
L
R
M
G
D
P
I
L
R
K
----
I
S
E
P
V
T
E
D
E
I
Q
T
----
K
E
F
K
K
L
I
R
D
--
M
F
D
T
M
R
H
A
--
E
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
E
D
--
N
ERYP
G
T
P
D
------
V
P
E
R
--
I
I
L
N
P
V
I
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
---------------
20
PsiBlast_PDB
63.25
34%
-46
- C7 -
1VEV
4
DEF_LEPIN
A:
[1-157]
--
S
V
R
K
I
L
R
M
G
D
P
I
L
R
K
----
I
S
E
P
V
T
E
D
E
I
Q
T
----
K
E
F
K
K
L
I
R
D
--
M
F
D
T
M
R
H
A
--
E
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
E
D
--
N
ERYP
G
T
P
D
------
V
P
E
R
--
I
I
L
N
P
V
I
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
---------------
33
PsiBlast_CBE
63.16
34%
-44
- C7 -
1Y6H
6
DEF_LEPIN
B:
[1-157]
--
S
V
R
K
I
L
R
M
G
D
P
I
L
R
K
----
I
S
E
P
V
T
E
D
E
I
Q
T
----
K
E
F
K
K
L
I
R
D
--
M
F
D
T
M
R
H
A
--
E
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
E
D
--
N
ERYP
G
T
P
D
------
V
P
E
R
--
I
I
L
N
P
V
I
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
---------------
36
PsiBlast_CBE
63.09
34%
-43
- C7 -
1VEY
2
DEF_LEPIN
B:
[1-157]
--
S
V
R
K
I
L
R
M
G
D
P
I
L
R
K
----
I
S
E
P
V
T
E
D
E
I
Q
T
----
K
E
F
K
K
L
I
R
D
--
M
F
D
T
M
R
H
A
--
E
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
E
D
--
N
ERYP
G
T
P
D
------
V
P
E
R
--
I
I
L
N
P
V
I
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
---------------
18
PsiBlast_PDB
62.96
34%
-45
- C7 -
1Y6H
5
DEF_LEPIN
A:
[1-157]
--
S
V
R
K
I
L
R
M
G
D
P
I
L
R
K
----
I
S
E
P
V
T
E
D
E
I
Q
T
----
K
E
F
K
K
L
I
R
D
--
M
F
D
T
M
R
H
A
--
E
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
E
D
--
N
ERYP
G
T
P
D
------
V
P
E
R
--
I
I
L
N
P
V
I
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
---------------
38
PsiBlast_CBE
62.76
34%
-45
- C7 -
1VEV
3
DEF_LEPIN
B:
[1-157]
--
S
V
R
K
I
L
R
M
G
D
P
I
L
R
K
----
I
S
E
P
V
T
E
D
E
I
Q
T
----
K
E
F
K
K
L
I
R
D
--
M
F
D
T
M
R
H
A
--
E
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
E
D
--
N
ERYP
G
T
P
D
------
V
P
E
R
--
I
I
L
N
P
V
I
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
---------------
37
PsiBlast_CBE
62.64
34%
-40
- C7 -
1VEY
2
DEF_LEPIN
A:
[1-157]
--
S
V
R
K
I
L
R
M
G
D
P
I
L
R
K
----
I
S
E
P
V
T
E
D
E
I
Q
T
----
K
E
F
K
K
L
I
R
D
--
M
F
D
T
M
R
H
A
--
E
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
E
D
--
N
ERYP
G
T
P
D
------
V
P
E
R
--
I
I
L
N
P
V
I
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
---------------
19
PsiBlast_PDB
62.58
34%
-50
- C7 -
1SV2
2
DEF_LEPIN
A:
[1-157]
--
S
V
R
K
I
L
R
M
G
D
P
I
L
R
K
----
I
S
E
P
V
T
E
D
E
I
Q
T
----
K
E
F
K
K
L
I
R
D
--
M
F
D
T
M
R
H
A
--
E
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
E
D
--
N
ERYP
G
T
P
D
------
V
P
E
R
--
I
I
L
N
P
V
I
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
---------------
35
PsiBlast_CBE
62.34
34%
-46
- C7 -
1VEZ
9
DEF_LEPIN
A:
[1-157]
--
S
V
R
K
I
L
R
M
G
D
P
I
L
R
K
----
I
S
E
P
V
T
E
D
E
I
Q
T
----
K
E
F
K
K
L
I
R
D
--
M
F
D
T
M
R
H
A
--
E
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
E
D
--
N
ERYP
G
T
P
D
------
V
P
E
R
--
I
I
L
N
P
V
I
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
---------------
34
PsiBlast_CBE
62.33
34%
-46
- C7 -
1VEZ
8
DEF_LEPIN
B:
[1-157]
--
S
V
R
K
I
L
R
M
G
D
P
I
L
R
K
----
I
S
E
P
V
T
E
D
E
I
Q
T
----
K
E
F
K
K
L
I
R
D
--
M
F
D
T
M
R
H
A
--
E
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
E
D
--
N
ERYP
G
T
P
D
------
V
P
E
R
--
I
I
L
N
P
V
I
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
---------------
56
PsiBlast_CBE
56.04
39%
-100
- C7 -
3M6R
3
DEF1B_ARATH
D:
[42-147]
------------------------------------------------------------
I
G
L
S
A
P
Q
V
G
L
N
V
Q
L
M
-
V
F
N
P
A
--
G
----
E
P
G
E
------
G
K
E
I
--
V
L
V
N
P
K
I
K
K
Y
S
--
D
K
L
V
P
F
D
E
G
C
L
S
F
P
G
I
Y
A
E
V
V
-
R
P
Q
S
V
K
I
D
A
R
D
I
T
G
E
R
F
S
I
S
L
S
R
L
P
A
R
I
F
Q
H
E
Y
D
H
L
E
G
V
L
F
F
D
R
M
---------------
47
PsiBlast_CBE
56.04
39%
-105
- C7 -
3O3J
3
DEF1B_ARATH
A:
[41-147]
-----------------------------------------------------------
G
I
G
L
S
A
P
Q
V
G
L
N
V
Q
L
M
-
V
F
N
P
A
--
G
----
E
P
G
E
------
G
K
E
I
--
V
L
V
N
P
K
I
K
K
Y
S
--
D
K
L
V
P
F
D
E
G
C
L
S
F
P
G
I
Y
A
E
V
V
-
R
P
Q
S
V
K
I
D
A
R
D
I
T
G
E
R
F
S
I
S
L
S
R
L
P
A
R
I
F
Q
H
E
Y
D
H
L
E
G
V
L
F
F
D
R
M
---------------
53
PsiBlast_CBE
56.01
39%
-112
- C7 -
3M6Q
3
DEF1B_ARATH
A:
[42-147]
------------------------------------------------------------
I
G
L
S
A
P
Q
V
G
L
N
V
Q
L
M
-
V
F
N
P
A
--
G
----
E
P
G
E
------
G
K
E
I
--
V
L
V
N
P
K
I
K
K
Y
S
--
D
K
L
V
P
F
D
E
G
C
L
S
F
P
G
I
Y
A
E
V
V
-
R
P
Q
S
V
K
I
D
A
R
D
I
T
G
E
R
F
S
I
S
L
S
R
L
P
A
R
I
F
Q
H
E
Y
D
H
L
E
G
V
L
F
F
D
R
M
---------------
59
PsiBlast_CBE
55.92
39%
-100
- C7 -
3M6R
5
DEF1B_ARATH
A:
[42-147]
------------------------------------------------------------
I
G
L
S
A
P
Q
V
G
L
N
V
Q
L
M
-
V
F
N
P
A
--
G
----
E
P
G
E
------
G
K
E
I
--
V
L
V
N
P
K
I
K
K
Y
S
--
D
K
L
V
P
F
D
E
G
C
L
S
F
P
G
I
Y
A
E
V
V
-
R
P
Q
S
V
K
I
D
A
R
D
I
T
G
E
R
F
S
I
S
L
S
R
L
P
A
R
I
F
Q
H
E
Y
D
H
L
E
G
V
L
F
F
D
R
M
---------------
58
PsiBlast_CBE
55.61
39%
-103
- C7 -
3M6R
4
DEF1B_ARATH
B:
[42-147]
------------------------------------------------------------
I
G
L
S
A
P
Q
V
G
L
N
V
Q
L
M
-
V
F
N
P
A
--
G
----
E
P
G
E
------
G
K
E
I
--
V
L
V
N
P
K
I
K
K
Y
S
--
D
K
L
V
P
F
D
E
G
C
L
S
F
P
G
I
Y
A
E
V
V
-
R
P
Q
S
V
K
I
D
A
R
D
I
T
G
E
R
F
S
I
S
L
S
R
L
P
A
R
I
F
Q
H
E
Y
D
H
L
E
G
V
L
F
F
D
R
M
---------------
43
PsiBlast_CBE
55.28
39%
-100
- C7 -
3PN4
3
DEF1B_ARATH
A:
[41-147]
-----------------------------------------------------------
G
I
G
L
S
A
P
Q
V
G
L
N
V
Q
L
M
-
V
F
N
P
A
--
G
----
E
P
G
E
------
G
K
E
I
--
V
L
V
N
P
K
I
K
K
Y
S
--
D
K
L
V
P
F
D
E
G
C
L
S
F
P
G
I
Y
A
E
V
V
-
R
P
Q
S
V
K
I
D
A
R
D
I
T
G
E
R
F
S
I
S
L
S
R
L
P
A
R
I
F
Q
H
E
Y
D
H
L
E
G
V
L
F
F
D
R
M
---------------
48
PsiBlast_CBE
54.96
39%
-106
- C7 -
3M6P
4
DEF1B_ARATH
B:
[41-147]
-----------------------------------------------------------
G
I
G
L
S
A
P
Q
V
G
L
N
V
Q
L
M
-
V
F
N
P
A
--
G
----
E
P
G
E
------
G
K
E
I
--
V
L
V
N
P
K
I
K
K
Y
S
--
D
K
L
V
P
F
D
E
G
C
L
S
F
P
G
I
Y
A
E
V
V
-
R
P
Q
S
V
K
I
D
A
R
D
I
T
G
E
R
F
S
I
S
L
S
R
L
P
A
R
I
F
Q
H
E
Y
D
H
L
E
G
V
L
F
F
D
R
M
---------------
57
PsiBlast_CBE
54.55
39%
-100
- C7 -
3M6R
4
DEF1B_ARATH
C:
[42-147]
------------------------------------------------------------
I
G
L
S
A
P
Q
V
G
L
N
V
Q
L
M
-
V
F
N
P
A
--
G
----
E
P
G
E
------
G
K
E
I
--
V
L
V
N
P
K
I
K
K
Y
S
--
D
K
L
V
P
F
D
E
G
C
L
S
F
P
G
I
Y
A
E
V
V
-
R
P
Q
S
V
K
I
D
A
R
D
I
T
G
E
R
F
S
I
S
L
S
R
L
P
A
R
I
F
Q
H
E
Y
D
H
L
E
G
V
L
F
F
D
R
M
---------------
49
PsiBlast_CBE
53.73
39%
-106
- C7 -
3M6P
4
DEF1B_ARATH
A:
[41-147]
-----------------------------------------------------------
G
I
G
L
S
A
P
Q
V
G
L
N
V
Q
L
M
-
V
F
N
P
A
--
G
----
E
P
G
E
------
G
K
E
I
--
V
L
V
N
P
K
I
K
K
Y
S
--
D
K
L
V
P
F
D
E
G
C
L
S
F
P
G
I
Y
A
E
V
V
-
R
P
Q
S
V
K
I
D
A
R
D
I
T
G
E
R
F
S
I
S
L
S
R
L
P
A
R
I
F
Q
H
E
Y
D
H
L
E
G
V
L
F
F
D
R
M
---------------