@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0951: (2016-03-20 )
MRNTNKFLLIPYLLWMVIFIIVPVVLLIYFSFLDINGHFSFTNYQQIFTTKYLKMFAYSILYAALITIITLAISYPAAYYITRSKFQNILLMIMIIPTWINLLLKTYAFIGLLSHDGVINQFFHLFNLPSFNLLFTTGAFLVVASYIYIPFMILPIFNSMKAIPNNLLQASSDLGASPFYTFRKVIMPLTKEGVMTGIQVTFIPSLSLFMITRLIAGNKVINIGTAIEEQFLTIQNYGMGSTIAIFLIVFMAFILIITKSSNGRG
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20........30.....------.-----------..40........-50.-----........60.....-...70........80.----..-.---------.--...90........100.......110...-.-...120..-....-.130.----.----.....--140.......150.......160.......170.......180.......190.......200.......210.......------------220.......230.---.---------------.....240..--.----...-----.250.......260...-----------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRNTN
K
F
L
L
I
P
Y
L
L
W
M
V
I
F
I
I
V
P
V
V
L
L
I
Y
F
S
F
LDIN------G-----------HFSF
T
N
Y
Q
Q
I
F
T
-
T
-
K
-----
Y
L
K
M
F
A
Y
S
I
L
Y
A
A
L
I
-
T
I
I
T
L
A
ISYP
A
A
Y
Y
I
T
----
R
S
-
K
---------
F
--
Q
N
I
L
L
M
I
M
I
I
P
T
W
I
N
L
L
L
K
T
Y
A
F
I
G
LLSH-
D
-
G
V
I
N
Q
F
F
H
-
L
FNL-PS
F
N
L
----
L
----
F
TT
G
A
--
F
L
V
V
A
S
Y
I
Y
I
P
F
M
I
L
P
I
F
N
S
M
K
A
I
P
N
N
L
L
Q
ASSDLGA
S
P
F
Y
T
F
R
K
V
I
M
P
L
T
K
E
GVMTG
I
Q
V
T
F
IP
S
L
S
L
F
M
I
T
R
L
IAGN
K
------------
V
I
N
I
G
T
A
I
E
E
Q
F
L
T
---
I
---------------QNYGM
G
S
T
I
A
--
I
----
F
L
I
-----
V
F
M
A
F
I
L
I
I
TKSSNGRG-----------------
11
PsiBlast_PDB
89.79
23%
-168
- C3 -
4KI0
5
MALF_ECOLI
F:
[260-498]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
W
K
N
F
T
R
V
F
T
-
D
-
E
GIQKP
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
-
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
WEAL
R
G
-
K
AV-------
Y
--
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
----
F
K
G
L
F
N
Q
-
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
A
W
F
S
----
D
----
P
T
T
A
R
TM
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
L
I
Q
L
L
T
N
G
G
------------
P
D
R
L
G
T
T
T
P
A
G
Y
T
D
---
L
LVNYTYRIAFEGGGG
Q
D
F
G
L
A
A
A
I
A
TL
I
----
F
L
L
-----
V
---------------------------------
2
PsiBlast_PDB
89.71
23%
-169
- C3 -
3PUY
2
MALF_ECOLI
F:
[260-498]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
W
K
N
F
T
R
V
F
T
-
D
-
E
GIQKP
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
-
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
WEAL
R
G
-
K
AV-------
Y
--
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
----
F
K
G
L
F
N
Q
-
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
A
W
F
S
----
D
----
P
T
T
A
R
TM
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
L
I
Q
L
L
T
N
G
G
------------
P
D
R
L
G
T
T
T
P
A
G
Y
T
D
---
L
LVNYTYRIAFEGGGG
Q
D
F
G
L
A
A
A
I
A
TL
I
----
F
L
L
-----
V
---------------------------------
21
HHSearch
89.70
19%
-173
- C3 -
2ONK
-
WTPB_ARCFU
C:
[28-275]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
S
A
L
L
A
L
L
S
S
I
I
L
L
F
V
L
L
P
V
A
A
T
V
T
L
Q
L
F
-----------------------
N
F
D
E
F
L
K
A
A
S
-
D
P
A
-----
V
W
K
V
V
L
T
T
Y
Y
A
A
L
I
S
-
T
L
I
A
V
I
F
G
T
P
L
A
Y
I
L
A
----
R
K
S
F
P--------
G
--
K
S
V
V
E
G
I
V
D
L
P
V
V
I
P
H
T
V
A
G
I
A
L
L
V
V
F
G
S
-
S
-
G
L
I
G
S
F
S
P
--------
L
K
F
----
V
----
D
A
L
P
G
--
I
V
V
A
M
L
F
V
S
V
P
I
Y
I
N
Q
A
K
E
G
F
A
S
V
D
V
R
L
E
H
V
A
R
T
L
G
S
S
P
L
R
V
F
F
T
V
S
L
P
L
S
V
R
H
I
V
A
G
A
I
M
S
W
A
R
G
I
S
E
F
G
A
V
V
V
I
A
Y
Y
-------------
P
M
I
A
P
T
L
I
Y
E
R
Y
L
----
S
---------------
E
G
L
S
A
A
M
P
V
A
--
A
----
I
L
I
-----
L
L
S
L
A
V
F
V
A
L
R
I
I
V
G
-------------------
7
PsiBlast_PDB
88.95
23%
-167
- C3 -
3PUX
3
MALF_ECOLI
F:
[260-498]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
W
K
N
F
T
R
V
F
T
-
D
-
E
GIQKP
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
-
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
WEAL
R
G
-
K
AV-------
Y
--
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
----
F
K
G
L
F
N
Q
-
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
A
W
F
S
----
D
----
P
T
T
A
R
TM
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
L
I
Q
L
L
T
N
G
G
------------
P
D
R
L
G
T
T
T
P
A
G
Y
T
D
---
L
LVNYTYRIAFEGGGG
Q
D
F
G
L
A
A
A
I
A
TL
I
----
F
L
L
-----
V
---------------------------------
10
PsiBlast_PDB
88.93
23%
-167
- C3 -
4KHZ
2
MALF_ECOLI
F:
[260-498]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
W
K
N
F
T
R
V
F
T
-
D
-
E
GIQKP
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
-
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
WEAL
R
G
-
K
AV-------
Y
--
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
----
F
K
G
L
F
N
Q
-
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
A
W
F
S
----
D
----
P
T
T
A
R
TM
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
L
I
Q
L
L
T
N
G
G
------------
P
D
R
L
G
T
T
T
P
A
G
Y
T
D
---
L
LVNYTYRIAFEGGGG
Q
D
F
G
L
A
A
A
I
A
TL
I
----
F
L
L
-----
V
---------------------------------
6
PsiBlast_PDB
88.89
23%
-167
- C3 -
3PUW
3
MALF_ECOLI
F:
[260-498]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
W
K
N
F
T
R
V
F
T
-
D
-
E
GIQKP
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
-
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
WEAL
R
G
-
K
AV-------
Y
--
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
----
F
K
G
L
F
N
Q
-
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
A
W
F
S
----
D
----
P
T
T
A
R
TM
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
L
I
Q
L
L
T
N
G
G
------------
P
D
R
L
G
T
T
T
P
A
G
Y
T
D
---
L
LVNYTYRIAFEGGGG
Q
D
F
G
L
A
A
A
I
A
TL
I
----
F
L
L
-----
V
---------------------------------
8
PsiBlast_PDB
88.23
23%
-167
- C3 -
3RLF
2
MALF_ECOLI
F:
[260-498]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
W
K
N
F
T
R
V
F
T
-
D
-
E
GIQKP
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
-
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
WEAL
R
G
-
K
AV-------
Y
--
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
----
F
K
G
L
F
N
Q
-
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
A
W
F
S
----
D
----
P
T
T
A
R
TM
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
L
I
Q
L
L
T
N
G
G
------------
P
D
R
L
G
T
T
T
P
A
G
Y
T
D
---
L
LVNYTYRIAFEGGGG
Q
D
F
G
L
A
A
A
I
A
TL
I
----
F
L
L
-----
V
---------------------------------
4
PsiBlast_PDB
88.04
23%
-167
- C3 -
3PV0
2
MALF_ECOLI
F:
[260-498]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
W
K
N
F
T
R
V
F
T
-
D
-
E
GIQKP
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
-
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
WEAL
R
G
-
K
AV-------
Y
--
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
----
F
K
G
L
F
N
Q
-
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
A
W
F
S
----
D
----
P
T
T
A
R
TM
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
L
I
Q
L
L
T
N
G
G
------------
P
D
R
L
G
T
T
T
P
A
G
Y
T
D
---
L
LVNYTYRIAFEGGGG
Q
D
F
G
L
A
A
A
I
A
TL
I
----
F
L
L
-----
V
---------------------------------
5
PsiBlast_PDB
87.80
23%
-170
- C3 -
3PUV
3
MALF_ECOLI
F:
[260-498]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
W
K
N
F
T
R
V
F
T
-
D
-
E
GIQKP
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
-
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
WEAL
R
G
-
K
AV-------
Y
--
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
----
F
K
G
L
F
N
Q
-
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
A
W
F
S
----
D
----
P
T
T
A
R
TM
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
L
I
Q
L
L
T
N
G
G
------------
P
D
R
L
G
T
T
T
P
A
G
Y
T
D
---
L
LVNYTYRIAFEGGGG
Q
D
F
G
L
A
A
A
I
A
TL
I
----
F
L
L
-----
V
---------------------------------
16
PsiBlast_PDB
87.79
22%
-160
- C3 -
2ONK
-
WTPB_ARCFU
C:
[56-275]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
F
D
E
F
L
K
A
A
S
-
D
-
P
-----
A
V
W
K
V
V
L
T
T
Y
Y
A
A
L
I
S
T
L
I
A
V
I
F
G
T
P
L
A
Y
I
L
A
----
R
K
-
S
---------
F
PG
K
S
V
V
E
G
I
V
D
L
P
V
V
I
P
H
T
V
A
G
I
A
L
L
V
V
F
G
S
-
S
-
G
L
I
G
S
F
S
P
-
L
-------
K
F
----
V
----
D
A
L
P
G
--
I
V
V
A
M
L
F
V
S
V
P
I
Y
I
N
Q
A
K
E
G
F
A
S
V
D
V
R
L
E
H
V
A
R
T
L
G
S
S
P
L
R
V
F
F
T
V
S
L
P
L
S
V
R
H
I
V
A
G
A
I
M
S
W
A
R
G
I
S
E
F
G
A
V
V
V
I
A
Y
Y
P
------------
M
I
A
-
P
T
L
I
Y
E
R
Y
L
S
-------------------
E
G
L
S
A
A
M
P
V
A
--
A
----
I
L
I
LLSLA
V
F
V
A
L
R
I
I
V
G
------------------------
3
PsiBlast_PDB
87.69
23%
-167
- C3 -
3PUZ
2
MALF_ECOLI
F:
[260-498]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
W
K
N
F
T
R
V
F
T
-
D
-
E
GIQKP
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
-
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
WEAL
R
G
-
K
AV-------
Y
--
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
----
F
K
G
L
F
N
Q
-
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
A
W
F
S
----
D
----
P
T
T
A
R
TM
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
L
I
Q
L
L
T
N
G
G
------------
P
D
R
L
G
T
T
T
P
A
G
Y
T
D
---
L
LVNYTYRIAFEGGGG
Q
D
F
G
L
A
A
A
I
A
TL
I
----
F
L
L
-----
V
---------------------------------
9
PsiBlast_PDB
87.65
23%
-172
- C3 -
4JBW
1
MALF_ECOLI
F:
[260-498]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
W
K
N
F
T
R
V
F
T
-
D
-
E
GIQKP
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
-
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
WEAL
R
G
-
K
AV-------
Y
--
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
----
F
K
G
L
F
N
Q
-
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
A
W
F
S
----
D
----
P
T
T
A
R
TM
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
L
I
Q
L
L
T
N
G
G
------------
P
D
R
L
G
T
T
T
P
A
G
Y
T
D
---
L
LVNYTYRIAFEGGGG
Q
D
F
G
L
A
A
A
I
A
TL
I
----
F
L
L
-----
V
---------------------------------
1
PsiBlast_PDB
87.36
23%
-170
- C3 -
2R6G
1
MALF_ECOLI
F:
[260-498]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
W
K
N
F
T
R
V
F
T
-
D
-
E
GIQKP
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
-
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
WEAL
R
G
-
K
AV-------
Y
--
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
----
F
K
G
L
F
N
Q
-
S
F
G
E
I
N
M
M
L
S
A
L
F
G
V
K
P
A
W
F
S
----
D
----
P
T
T
A
R
TM
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
L
I
Q
L
L
T
N
G
G
------------
P
D
R
L
G
T
T
T
P
A
G
Y
T
D
---
L
LVNYTYRIAFEGGGG
Q
D
F
G
L
A
A
A
I
A
TL
I
----
F
L
L
-----
V
---------------------------------
23
HHSearch
87.27
19%
-163
- C3 -
3RLF
2
MALF_ECOLI
F:
[258-503]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
G
W
K
N
F
T
R
V
F
T
-
D
E
G
IQKP-
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
-
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
----
W
E
A
L
R--------
G
--
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
F
-
G
E
I
N
M
M
L
S
-
A
L
F
G
-
V
K
P
A
W
FSDP
T
----
T
A
R
T
M
--
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
L
I
Q
L
L
T
N
G
G
PDRLGTTTPAGY
T
D
L
L
V
N
Y
T
Y
R
I
A
F
E
GGG
G
---------------
Q
D
F
G
L
A
A
A
I
A
--
T
----
L
I
F
-----
L
L
V
G
A
L
A
I
--------------------------
22
HHSearch
84.39
18%
-172
- C3 -
3D31
-
?
C:
[44-283]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
L
V
L
F
L
F
I
F
L
T
L
S
N
M
I
F
E
Q
I
T
E
----------------------
D
F
S
G
L
V
K
A
A
G
-
N
R
S
-----
V
I
S
S
I
F
L
S
L
Y
A
G
F
L
A
-
T
L
L
A
L
L
L
G
A
P
T
G
Y
I
L
A
----
R
F
D
F
P--------
G
--
K
R
L
V
E
S
I
I
D
V
P
V
V
V
P
H
T
V
A
G
I
A
L
L
T
V
F
G
S
-
R
-
G
L
I
G
E
P
L
E
-
S
Y
-----
I
Q
F
----
R
----
D
A
L
P
G
--
I
V
V
A
M
L
F
V
S
M
P
Y
L
A
N
S
A
R
E
G
F
K
S
V
D
P
R
L
E
N
A
A
R
S
L
G
A
P
L
W
K
A
F
F
F
V
T
L
P
L
S
A
R
Y
L
L
I
G
S
V
M
T
W
A
R
A
I
S
E
F
G
A
V
V
I
L
A
Y
Y
-------------
P
M
V
G
P
T
L
I
Y
D
R
F
I
----
S
---------------
Y
G
L
S
A
S
R
P
I
A
--
V
----
L
L
I
-----
L
V
T
L
S
I
F
L
V
I
R
-----------------------
32
Fugue
84.25
17%
-173
- C3 -
2R6G
1
MALF_ECOLI
F:
[13-504]
DALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYT
L
D
G
D
G
T
L
T
N
N
Q
S
G
V
K
Y
R
P
N
N
Q
I
G
F
Y
Q
S
I
T
A
N
W
G
D
E
K
LSPGYT
V
-----------
T
T
G
W
K
N
F
T
R
V
F
T
-
D
-
E
GIQKP
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
-
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
----
W
E
-
A
---------
L
RG
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
-
S
F
G
E
I
N
M
M
L
S
-
A
L
F
G
-
V
K
P
A
W
----
F
SDPT
T
A
R
T
M
--
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
L
I
Q
L
L
T
N
G
G
------------
P
D
R
L
G
T
----------------------------
T
T
P
A
G
Y
T
D
L
--
L
----
V
N
Y
-----
T
Y
R
I
A
F
E
G
G
G
G
Q
D
F
G
L
A
AAIATLIFLLVGALAIV
33
Fugue
83.46
19%
-151
- C3 -
3FH6
-
MALG_ECOLI
G:
[3-287]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
Q
P
K
S
Q
K
A
R
L
F
I
T
H
L
L
L
L
L
F
I
A
A
I
M
F
P
L
L
M
V
V
A
I
---------------------
S
L
R
Q
R
I
T
P
P
P
-
F
-
P
-----
V
L
L
W
L
W
N
S
V
K
V
A
G
I
S
-
A
I
G
I
V
A
L
S
T
T
C
A
Y
A
F
A
----
R
M
-
R
---------
F
PG
K
A
T
L
L
K
G
M
L
I
F
Q
M
F
P
A
V
L
S
L
V
A
L
Y
A
L
F
D
R
-
L
-
G
E
Y
I
P
F
I
G
-
L
-------------------
N
T
H
G
--
G
V
I
F
A
Y
L
G
G
I
A
L
H
V
W
T
I
K
G
Y
F
E
T
I
D
S
S
L
E
E
A
A
A
L
D
G
A
T
P
W
Q
A
F
R
L
V
L
L
P
L
S
V
P
I
L
A
V
V
F
I
L
S
F
I
A
A
I
T
E
V
P
V
A
S
L
L
L
R
D
V
------------
N
S
Y
T
L
A
V
G
M
Q
Q
Y
L
N
---
P
---------------
Q
N
Y
L
W
G
D
F
A
A
--
A
----
A
V
M
-----
S
A
L
P
I
T
I
V
F
L
L
A
Q
R
W
L
V
N----------------
31
Fugue
82.86
18%
-170
* C3 *
2ONK
-
WTPB_ARCFU
C:
[24-275]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
L
L
F
S
A
L
L
A
L
L
S
S
I
I
L
L
F
V
L
L
P
V
A
A
T
V
T
L
Q
L
F
N
F
D
------
E
-----------
F
L
K
A
A
S
-----
D
-
P
-
A
-----
V
W
K
V
V
L
T
T
Y
Y
A
A
L
I
S
-
T
L
I
A
V
I
F
G
T
P
L
A
Y
I
L
A
----
R
K
-
S
---------
F
PG
K
S
V
V
E
G
I
V
D
L
P
V
V
I
P
H
T
V
A
G
I
A
L
L
V
V
F
G
S
-
S
-
G
L
I
G
S
F
S
P
-
L
-------
K
F
----
V
----
D
A
L
P
G
--
I
V
V
A
M
L
F
V
S
V
P
I
Y
I
N
Q
A
K
E
G
F
A
S
V
D
V
R
L
E
H
V
A
R
T
L
G
S
S
P
L
R
V
F
F
T
V
S
L
P
L
S
V
R
H
I
V
A
G
A
I
M
S
W
A
R
G
I
S
E
F
G
A
V
V
V
I
A
Y
Y
P
------------
M
I
----
A
P
T
L
I
Y
E
R
---
Y
---------------
L
S
E
G
L
S
A
A
M
P
--
V
----
A
A
I
-----
L
I
L
L
S
L
A
V
F
V
A
L
R
I
I
V
G
-----------------
24
HHSearch
75.33
16%
-154
- C3 -
3TUI
-
METI_ECOLI
A:
[8-212]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-----
L
V
R
G
V
W
E
T
L
A
M
T
F
V
S
-
G
F
F
G
F
V
I
G
L
P
V
G
V
L
L
Y
----
V
T
-
R
PGQIIAN
A
K
L
--
Y
R
T
V
S
A
I
V
N
I
F
R
S
I
P
F
I
I
L
L
V
W
M
I
P
F
T
R
V
-
I
-----------
V
G
------
T
----
S
----
I
G
L
Q
A
--
A
I
V
P
L
T
V
G
A
A
P
F
I
A
R
M
V
E
N
A
L
L
E
I
P
T
G
L
I
E
A
S
R
A
M
G
A
T
P
M
Q
I
V
R
K
V
L
L
P
E
A
L
P
G
L
V
N
A
A
T
I
T
L
I
T
L
V
G
Y
S
A
M
G
G
A
V
G
A
---------------
G
G
L
G
Q
I
G
Y
Q
Y
G
Y
I
---
G
---------------
Y
N
A
T
V
M
N
T
V
L
--
V
----
L
L
V
-----
I
L
V
Y
L
I
Q
F
A
G
D
R
I
V
R
-------------------
36
Fugue
74.36
14%
-146
- C3 -
4TQU
-
?
N:
[2-284]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LATPFYSR
S
D
R
I
F
G
I
V
N
A
V
L
L
G
I
F
A
L
C
A
L
Y
P
I
I
Y
I
F
S
M
S
I
S
S
G
A
------
A
VTQGRVFLLPV
D
I
D
F
S
A
Y
G
R
V
L
H
D
K
-
L
-----
F
W
T
S
Y
A
N
T
I
F
Y
T
V
F
G
-
V
V
T
S
L
I
F
I
V
P
G
A
Y
A
L
S
----
K
P
-
R
---------
I
-------------
R
G
R
R
V
F
G
F
I
I
A
F
T
M
W
F
N
--
A
-
G
M
I
P
F
F
L
N
-
M
R
D
L
-
G
L
L
D
-------------
N
R
--
F
G
I
L
I
G
F
A
C
N
A
F
N
I
I
L
M
R
N
Y
F
E
S
I
S
A
S
F
E
E
A
A
R
M
D
G
A
N
D
L
Q
I
L
W
K
V
Y
I
P
L
A
K
P
A
L
A
T
I
T
L
L
C
A
I
S
R
W
N
G
Y
F
W
A
M
V
L
L
R
A
E
------------
E
K
I
P
L
Q
V
Y
L
K
K
T
I
V
---
D
---------------
L
N
V
N
E
E
F
A
G
A
--
L
LTNS
Y
S
M
-----
E
T
V
V
G
A
I
I
V
M
S
I
I
P
V
I
I
VYPVVQKYFTK------