@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1074: (2016-03-21 )
MKMTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
Atome Classification :
(38 SA)
.........10........20........30........40........50.-.......60........70........80-----.........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200-........210.......220....-...-230.......240....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKM
T
K
S
A
L
V
T
GASRGI
G
R
S
I
A
L
Q
L
A
EEG
Y
N
V
A
V
N
YAG
S
K
E
K
A
E
A
V
V
E
E
I
K
AK-GV
D
S
F
A
I
Q
ANVA
D
A
D
E
V
K
A
M
I
K
E
V
V
S
Q
F------GS
L
D
V
L
VNNAGI
T
R
D
N
L
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
K
A
T
P
Q
M
L
R
Q
RSG
A
I
I
N
L
S
S
V
V
GAVGNPGQA
N
Y
V
A
TKAGVIGL
T
K
S
A
A
R
E
L
A
SRG
I
T
V
NAVAP
G
F
I
V
S
D
M
T
D
A
L
S
D
E
L
K
-
E
-
Q
M
L
T
QI
P
L
A
RFGQDT
D
I
A
N
T
V
A
F
L
A-SDK-A
K
Y
I
TG
Q
T
I
H
VNGGMYM
2
PsiBlast_PDB
95.01
96%
-85
- C1 -
3OSU
15
FABG_STAAM
A:
[2-245]
-
K
M
T
K
S
A
L
V
T
G
A
S
R
G
I
G
R
S
I
A
L
Q
L
A
E
E
G
Y
N
V
A
V
N
Y
A
G
S
K
E
K
A
E
A
V
V
E
E
I
K
A
K
-
G
V
D
S
F
A
I
Q
A
N
V
A
D
A
D
E
V
K
A
M
I
K
E
V
V
S
Q
F
------
G
S
L
D
V
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
K
A
T
P
Q
M
L
R
Q
R
S
G
A
I
I
N
L
S
S
V
V
G
A
V
G
N
P
G
Q
A
N
Y
V
A
T
K
A
G
V
I
G
L
T
K
S
A
A
R
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
V
S
D
M
T
D
A
L
S
D
E
L
K
-
E
-
Q
M
L
T
Q
I
P
L
A
R
F
G
Q
D
T
D
I
A
N
T
V
A
F
L
A
-
S
D
K
-
A
K
Y
I
T
G
Q
T
I
H
V
N
G
G
M
Y
-
21
PsiBlast_CBE
93.63
100%
-85
- C1 -
3SJ7
2
?
B:
[9-252]
--
M
T
K
S
A
L
V
T
G
A
S
R
G
I
G
R
S
I
A
L
Q
L
A
E
E
G
Y
N
V
A
V
N
Y
A
G
S
K
E
K
A
E
A
V
V
E
E
I
K
A
K
-
G
V
D
S
F
A
I
Q
A
N
V
A
D
A
D
E
V
K
A
M
I
K
E
V
V
S
Q
F
------
G
S
L
D
V
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
K
A
T
P
Q
M
L
R
Q
R
S
G
A
I
I
N
L
S
S
V
V
G
A
V
G
N
P
G
Q
A
N
Y
V
A
T
K
A
G
V
I
G
L
T
K
S
A
A
R
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
V
S
D
-
T
D
A
L
S
D
E
L
K
-
E
-
Q
M
L
T
Q
I
P
L
A
R
F
G
Q
D
T
D
I
A
N
T
V
A
F
L
A
-
S
D
K
-
A
K
Y
I
T
G
Q
T
I
H
V
N
G
G
M
Y
M
1
PsiBlast_PDB
92.65
100%
-83
- C1 -
3SJ7
3
?
A:
[10-252]
---
T
K
S
A
L
V
T
G
A
S
R
G
I
G
R
S
I
A
L
Q
L
A
E
E
G
Y
N
V
A
V
N
Y
A
G
S
K
E
K
A
E
A
V
V
E
E
I
K
A
K
-
G
V
D
S
F
A
I
Q
A
N
V
A
D
A
D
E
V
K
A
M
I
K
E
V
V
S
Q
F
------
G
S
L
D
V
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
K
A
T
P
Q
M
L
R
Q
R
S
G
A
I
I
N
L
S
S
V
V
G
A
V
G
N
P
G
Q
A
N
Y
V
A
T
K
A
G
V
I
G
L
T
K
S
A
A
R
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
V
S
D
M
T
----
D
E
L
K
-
E
-
Q
M
L
T
Q
I
P
L
A
R
F
G
Q
D
T
D
I
A
N
T
V
A
F
L
A
-
S
D
K
-
A
K
Y
I
T
G
Q
T
I
H
V
N
G
G
M
Y
M
23
PsiBlast_CBE
83.61
62%
-83
- C1 -
4JRO
1
?
C:
[30-271]
----
K
V
A
V
V
T
G
G
S
R
G
I
G
R
D
I
A
I
N
L
A
K
E
G
A
N
I
F
F
N
Y
N
G
S
P
E
A
A
E
E
T
A
K
L
V
A
E
H
-
G
V
E
V
E
A
M
K
A
N
V
A
I
A
E
D
V
D
A
F
F
K
Q
A
I
E
R
F
------
G
R
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
D
E
W
D
D
V
I
N
I
N
L
K
G
T
F
L
C
T
K
A
V
S
R
T
M
M
K
Q
R
A
G
K
I
I
N
M
A
S
V
V
G
L
I
G
N
A
G
Q
A
N
Y
V
A
S
K
A
G
V
I
G
L
T
K
T
T
A
R
E
L
A
P
R
G
I
N
V
N
A
V
A
P
G
F
I
T
T
D
M
T
D
K
L
D
E
K
T
K
-
E
-
A
M
L
A
Q
I
P
L
G
A
Y
G
T
T
E
D
I
A
N
A
V
L
F
L
A
-
S
D
A
-
S
K
Y
I
T
G
Q
T
L
S
V
D
G
G
M
V
M
4
PsiBlast_PDB
82.55
62%
-82
- C1 -
4JRO
-
?
A:
[30-271]
----
K
V
A
V
V
T
G
G
S
R
G
I
G
R
D
I
A
I
N
L
A
K
E
G
A
N
I
F
F
N
Y
N
G
S
P
E
A
A
E
E
T
A
K
L
V
A
E
H
-
G
V
E
V
E
A
M
K
A
N
V
A
I
A
E
D
V
D
A
F
F
K
Q
A
I
E
R
F
------
G
R
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
D
E
W
D
D
V
I
N
I
N
L
K
G
T
F
L
C
T
K
A
V
S
R
T
M
M
K
Q
R
A
G
K
I
I
N
M
A
S
V
V
G
L
I
G
N
A
G
Q
A
N
Y
V
A
S
K
A
G
V
I
G
L
T
K
T
T
A
R
E
L
A
P
R
G
I
N
V
N
A
V
A
P
G
F
I
T
T
D
M
T
D
K
L
D
E
K
T
K
-
E
-
A
M
L
A
Q
I
P
L
G
A
Y
G
T
T
E
D
I
A
N
A
V
L
F
L
A
-
S
D
A
-
S
K
Y
I
T
G
Q
T
L
S
V
D
G
G
M
V
M
3
PsiBlast_PDB
80.73
64%
-82
- C1 -
2UVD
-
?
A:
[5-246]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
I
D
L
A
K
Q
G
A
N
V
V
V
N
Y
A
G
N
E
Q
K
A
N
E
V
V
D
E
I
K
K
L
-
G
S
D
A
I
A
V
R
A
D
V
A
N
A
E
D
V
T
N
M
V
K
Q
T
V
D
V
F
------
G
Q
V
D
I
L
V
N
N
A
G
V
T
K
D
N
L
L
M
R
M
K
E
E
E
W
D
T
V
I
N
T
N
L
K
G
V
F
L
C
T
K
A
V
S
R
F
M
M
R
Q
R
H
G
R
I
V
N
I
A
S
V
V
G
V
T
G
N
P
G
Q
A
N
Y
V
A
A
K
A
G
V
I
G
L
T
K
T
S
A
K
E
L
A
S
R
N
I
T
V
N
A
I
A
P
G
F
I
A
T
D
M
T
D
V
L
D
E
N
I
K
-
A
-
E
M
L
K
L
I
P
A
A
Q
F
G
E
A
Q
D
I
A
N
A
V
T
F
F
A
-
S
D
Q
-
S
K
Y
I
T
G
Q
T
L
N
V
D
G
G
M
V
M
22
PsiBlast_CBE
79.29
62%
-78
- C1 -
4JRO
1
?
D:
[30-271]
----
K
V
A
V
V
T
G
G
S
R
G
I
G
R
D
I
A
I
N
L
A
K
E
G
A
N
I
F
F
N
Y
N
G
S
P
E
A
A
E
E
T
A
K
L
V
A
E
H
-
G
V
E
V
E
A
M
K
A
N
V
A
I
A
E
D
V
D
A
F
F
K
Q
A
I
E
R
F
------
G
R
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
D
E
W
D
D
V
I
N
I
N
L
K
G
T
F
L
C
T
K
A
V
S
R
T
M
M
K
Q
R
A
G
K
I
I
N
M
A
S
V
V
G
L
I
G
N
A
G
Q
A
N
Y
V
A
S
K
A
G
V
I
G
L
T
K
T
T
A
R
E
L
A
P
R
G
I
N
V
N
A
V
A
P
G
F
I
T
T
D
M
T
---
D
E
K
T
K
-
E
-
A
M
L
A
Q
I
P
L
G
A
Y
G
T
T
E
D
I
A
N
A
V
L
F
L
A
-
S
D
A
-
S
K
Y
I
T
G
Q
T
L
S
V
D
G
G
M
V
M
30
PsiBlast_CBE
79.23
55%
-81
- C1 -
1Q7B
3
FABG_ECOLI
D:
[6-243]
----
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
-
I
G
T
A
T
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
N
-
G
K
---
G
L
M
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
------
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
Y
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
A
L
S
D
D
Q
R
-
A
-
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
-
S
D
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
31
PsiBlast_CBE
78.36
55%
-84
- C1 -
1Q7B
3
FABG_ECOLI
C:
[6-243]
----
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
-
I
G
T
A
T
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
N
-
G
K
---
G
L
M
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
------
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
Y
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
A
L
S
D
D
Q
R
-
A
-
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
-
S
D
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
5
PsiBlast_PDB
77.96
60%
-90
- C1 -
4RZH
-
?
A:
[9-246]
------
A
L
V
T
G
A
S
R
G
I
G
K
A
T
A
L
A
L
A
A
T
G
M
K
V
V
V
N
Y
A
Q
S
S
T
A
A
D
A
V
V
A
E
I
I
A
N
-
G
G
E
A
I
A
V
Q
A
N
V
A
N
A
D
E
V
D
Q
L
I
K
T
T
L
D
K
F
------
S
R
I
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
L
E
D
W
Q
A
V
I
D
L
N
L
T
G
V
F
L
C
T
K
A
V
S
K
L
M
L
K
Q
K
S
G
R
I
I
N
I
T
S
V
A
G
M
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
F
T
K
T
V
A
K
E
L
A
S
R
G
V
T
V
N
A
V
A
P
G
F
I
A
---------------
P
I
L
Q
F
I
P
L
A
R
Y
G
Q
P
E
E
V
A
G
T
I
R
F
L
A
-
T
D
P
A
A
A
Y
I
T
G
Q
T
F
N
V
D
G
G
M
V
M
13
PsiBlast_PDB
77.82
54%
-81
- C1 -
1Q7C
1
FABG_ECOLI
A:
[6-243]
----
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
-
I
G
T
A
T
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
N
-
G
K
---
G
L
M
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
------
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
F
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
A
L
S
D
D
Q
R
-
A
-
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
-
S
D
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
9
PsiBlast_PDB
77.66
55%
-81
- C1 -
1Q7B
4
FABG_ECOLI
A:
[6-243]
----
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
-
I
G
T
A
T
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
N
-
G
K
---
G
L
M
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
------
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
Y
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
A
L
S
D
D
Q
R
-
A
-
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
-
S
D
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
19
PsiBlast_PDB
77.55
59%
-71
- C1 -
4DMM
1
?
A:
[29-268]
----
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
V
N
Y
A
S
S
A
G
A
A
D
E
V
V
A
A
I
A
A
A
-
G
G
E
A
F
A
V
K
A
D
V
S
Q
E
S
E
V
E
A
L
F
A
A
V
I
E
R
W
------
G
R
L
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
K
I
M
L
K
Q
R
S
G
R
I
I
N
I
A
S
V
V
G
E
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
D
M
T
S
E
L
A
---
A
-
E
-
K
L
L
E
V
I
P
L
G
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
-
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
44
PsiBlast_CBE
77.45
54%
-84
- C1 -
3TZH
14
?
F:
[13-250]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
----
G
D
N
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
A
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
-
T
-
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
18
PsiBlast_PDB
77.32
59%
-84
- C1 -
4DML
-
?
A:
[9-248]
----
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
V
N
Y
A
S
S
A
G
A
A
D
E
V
V
A
A
I
A
A
A
-
G
G
E
A
F
A
V
K
A
D
V
S
Q
E
S
E
V
E
A
L
F
A
A
V
I
E
R
W
------
G
R
L
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
K
I
M
L
K
Q
R
S
G
R
I
I
N
I
A
S
V
V
G
E
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
D
M
--------
A
-
E
-
K
L
L
E
V
I
P
L
G
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
-
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
16
PsiBlast_PDB
77.23
54%
-84
- C1 -
3TZK
8
?
A:
[13-250]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
----
G
D
N
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
A
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
-
T
-
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
51
PsiBlast_CBE
76.82
50%
-78
* C1 *
2PNF
3
FABG_AQUAE
B:
[8-248]
----
K
V
S
L
V
T
G
S
T
R
G
I
G
R
A
I
A
E
K
L
A
S
A
G
S
T
V
I
I
T
-
G
T
S
G
E
R
A
K
A
V
A
E
E
I
A
N
K
Y
G
V
K
A
H
G
V
E
M
N
L
L
S
E
E
S
I
N
K
A
F
E
E
I
Y
N
L
V
------
D
G
I
D
I
L
V
N
N
A
G
I
T
R
D
K
L
F
L
R
M
S
L
L
D
W
E
E
V
L
K
V
N
L
T
G
T
F
L
V
T
Q
N
S
L
R
K
M
I
K
Q
R
W
G
R
I
V
N
I
S
S
V
V
G
F
T
G
N
V
G
Q
V
N
Y
S
T
T
K
A
G
L
I
G
F
T
K
S
L
A
K
E
L
A
P
R
N
V
L
V
N
A
V
A
P
G
F
I
E
T
D
M
T
A
V
L
S
E
E
I
K
-
Q
-
K
Y
K
E
Q
I
P
L
G
R
F
G
S
P
E
E
V
A
N
V
V
L
F
L
C
-
S
E
L
-
A
S
Y
I
T
G
E
V
I
H
V
N
G
G
M
F
-
36
PsiBlast_CBE
76.73
54%
-80
- C1 -
1Q7C
1
FABG_ECOLI
B:
[6-243]
----
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
-
I
G
T
A
T
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
N
-
G
K
---
G
L
M
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
------
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
F
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
A
L
S
D
D
Q
R
-
A
-
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
-
S
D
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
49
PsiBlast_CBE
76.66
54%
-84
- C1 -
3TZH
9
?
A:
[13-250]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
----
G
D
N
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
A
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
-
T
-
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
24
PsiBlast_CBE
76.59
62%
-80
- C1 -
4JRO
1
?
B:
[30-271]
----
K
V
A
V
V
T
G
G
S
R
G
I
G
R
D
I
A
I
N
L
A
K
E
G
A
N
I
F
F
N
Y
N
G
S
P
E
A
A
E
E
T
A
K
L
V
A
E
H
-
G
V
E
V
E
A
M
K
A
N
V
A
I
A
E
D
V
D
A
F
F
K
Q
A
I
E
R
F
------
G
R
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
D
E
W
D
D
V
I
N
I
N
L
K
G
T
F
L
C
T
K
A
V
S
R
T
M
M
K
Q
R
A
G
K
I
I
N
M
A
S
V
V
G
L
I
G
N
A
G
Q
A
N
Y
V
A
S
K
A
G
V
I
G
L
T
K
T
T
A
R
E
L
A
P
R
G
I
N
V
N
A
V
A
P
G
F
I
T
T
D
---------
K
-
E
-
A
M
L
A
Q
I
P
L
G
A
Y
G
T
T
E
D
I
A
N
A
V
L
F
L
A
-
S
D
A
-
S
K
Y
I
T
G
Q
T
L
S
V
D
G
G
M
V
M
42
PsiBlast_CBE
76.50
59%
-81
- C1 -
4DMM
1
?
C:
[29-268]
----
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
V
N
Y
A
S
S
A
G
A
A
D
E
V
V
A
A
I
A
A
A
-
G
G
E
A
F
A
V
K
A
D
V
S
Q
E
S
E
V
E
A
L
F
A
A
V
I
E
R
W
------
G
R
L
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
K
I
M
L
K
Q
R
S
G
R
I
I
N
I
A
S
V
V
G
E
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
D
M
----------
E
-
K
L
L
E
V
I
P
L
G
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
-
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
52
PsiBlast_CBE
76.31
50%
-76
- C1 -
2PNF
3
FABG_AQUAE
A:
[8-248]
----
K
V
S
L
V
T
G
S
T
R
G
I
G
R
A
I
A
E
K
L
A
S
A
G
S
T
V
I
I
T
-
G
T
S
G
E
R
A
K
A
V
A
E
E
I
A
N
K
Y
G
V
K
A
H
G
V
E
M
N
L
L
S
E
E
S
I
N
K
A
F
E
E
I
Y
N
L
V
------
D
G
I
D
I
L
V
N
N
A
G
I
T
R
D
K
L
F
L
R
M
S
L
L
D
W
E
E
V
L
K
V
N
L
T
G
T
F
L
V
T
Q
N
S
L
R
K
M
I
K
Q
R
W
G
R
I
V
N
I
S
S
V
V
G
F
T
G
N
V
G
Q
V
N
Y
S
T
T
K
A
G
L
I
G
F
T
K
S
L
A
K
E
L
A
P
R
N
V
L
V
N
A
V
A
P
G
F
I
E
T
D
M
T
A
V
L
S
E
E
I
K
-
Q
-
K
Y
K
E
Q
I
P
L
G
R
F
G
S
P
E
E
V
A
N
V
V
L
F
L
C
-
S
E
L
-
A
S
Y
I
T
G
E
V
I
H
V
N
G
G
M
F
-
41
PsiBlast_CBE
75.98
59%
-79
- C1 -
4DMM
1
?
D:
[29-268]
----
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
V
N
Y
A
S
S
A
G
A
A
D
E
V
V
A
A
I
A
A
A
-
G
G
E
A
F
A
V
K
A
D
V
S
Q
E
S
E
V
E
A
L
F
A
A
V
I
E
R
W
------
G
R
L
D
V
L
V
N
N
A
G
I
T
R
D
T
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
K
I
M
L
K
Q
R
S
G
R
I
I
N
I
A
S
V
V
G
E
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
--------------
K
L
L
E
V
I
P
L
G
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
-
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
32
PsiBlast_CBE
75.79
55%
-80
- C1 -
1Q7B
4
FABG_ECOLI
B:
[6-243]
----
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
-
I
G
T
A
T
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
N
-
G
K
---
G
L
M
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
------
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
Y
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
--
S
D
D
Q
R
-
A
-
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
-
S
D
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
35
PsiBlast_CBE
75.75
54%
-83
- C1 -
3RRO
13
FABG_VIBCH
B:
[13-250]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
----
G
D
N
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
-
T
-
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
33
PsiBlast_CBE
75.67
54%
-82
- C1 -
4I08
9
FABG_VIBCH
B:
[13-250]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
----
G
D
N
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
--
T
K
A
L
N
D
E
Q
R
-
T
-
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
11
PsiBlast_PDB
75.49
54%
-81
- C1 -
3RRO
11
FABG_VIBCH
A:
[13-250]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
----
G
D
N
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
-
T
-
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
10
PsiBlast_PDB
75.39
54%
-82
- C1 -
3RSH
11
FABG_VIBCH
A:
[13-250]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
----
G
D
N
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
---
D
E
Q
R
-
T
-
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
50
PsiBlast_CBE
75.30
53%
-78
- C1 -
1EDO
1
FABG1_BRANA
A:
[5-242]
-------
V
V
T
G
A
S
R
G
I
G
K
A
I
A
L
S
L
G
K
A
G
C
K
V
L
V
N
Y
A
R
S
A
K
A
A
E
E
V
S
K
Q
I
E
A
Y
-
G
G
Q
A
I
T
F
G
G
D
V
S
K
E
A
D
V
E
A
M
M
K
T
A
I
D
A
W
------
G
T
I
D
V
V
V
N
N
A
G
I
T
R
D
T
L
L
I
R
M
K
K
S
Q
W
D
E
V
I
D
L
N
L
T
G
V
F
L
C
T
Q
A
A
T
K
I
M
M
K
K
R
K
G
R
I
I
N
I
A
S
V
V
G
L
I
G
N
I
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
S
K
T
A
A
R
E
G
A
S
R
N
I
N
V
N
V
V
C
P
G
F
I
A
S
D
M
T
A
K
L
G
E
D
M
E
-
K
-
K
I
L
G
T
I
P
L
G
R
T
G
Q
P
E
N
V
A
G
L
V
E
F
L
A
L
S
P
A
-
A
S
Y
I
T
G
Q
A
F
T
I
D
G
G
I
--
7
PsiBlast_PDB
75.23
54%
-91
- C1 -
4WK6
1
?
A:
[13-249]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
----
G
D
N
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
A
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
-
T
-
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
-
27
PsiBlast_CBE
75.12
54%
-91
- C1 -
4WK6
1
?
B:
[13-249]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
----
G
D
N
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
A
S
V
V
G
T
M
----
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
-
T
-
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
-
12
PsiBlast_PDB
74.94
54%
-84
- C1 -
4I08
6
FABG_VIBCH
A:
[13-250]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
----
G
D
N
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
----
N
D
E
Q
R
-
T
-
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
34
PsiBlast_CBE
74.13
54%
-82
- C1 -
3RSH
12
FABG_VIBCH
B:
[13-250]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
----
G
D
N
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
-
L
N
D
E
Q
R
-
T
-
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
26
PsiBlast_CBE
73.23
54%
-87
- C1 -
4WK6
2
?
C:
[13-249]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
----
G
D
N
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
A
S
V
V
G
------
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
-
T
-
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
-
25
PsiBlast_CBE
71.16
54%
-90
- C1 -
4WK6
2
?
D:
[13-249]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
----
G
D
N
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
---
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
A
S
---------
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
E
Q
R
-
T
-
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
-
14
PsiBlast_PDB
68.19
54%
-93
- C1 -
3TZC
5
?
A:
[13-249]
----
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
----
G
D
N
G
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
----
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
------------
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
-----
D
E
Q
R
-
T
-
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
-
S
P
E
-
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
-
111
HHSearch
68.01
40%
-74
- C1 -
3ICC
5
?
A:
[4-254]
M
L
K
G
K
V
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
K
R
L
A
N
D
G
A
L
V
A
I
H
Y
G
N
R
K
E
E
A
E
E
T
V
Y
E
I
Q
S
N
-
G
G
S
A
F
S
I
G
A
N
L
E
S
L
H
G
V
E
A
L
Y
S
S
L
D
N
E
L
Q
N
R
TGS
T
K
F
D
I
L
I
N
N
A
G
I
G
P
G
A
F
I
E
E
T
T
E
Q
F
F
D
R
M
V
S
V
N
A
K
A
P
F
F
I
I
Q
Q
A
L
S
R
L
R
D
--
N
S
R
I
I
N
I
S
S
A
A
T
R
I
S
L
P
D
F
I
A
Y
S
M
T
K
G
A
I
N
T
M
T
F
T
L
A
K
Q
L
G
A
R
G
I
T
V
N
A
I
L
P
G
F
V
K
T
D
M
N
A
E
L
L
S
D
P
M
M
K
Q
Y
A
T
T
I
S
A
F
N
R
L
G
E
V
E
D
I
A
D
T
A
A
F
L
A
-
S
P
D
-
S
R
W
V
T
G
Q
L
I
D
V
S
G
G
S
C
-
113
HHSearch
55.51
30%
-75
- C1 -
3GED
4
?
A:
[2-230]
---
N
R
G
V
I
V
T
G
G
G
H
G
I
G
K
Q
I
C
L
D
F
L
E
A
G
D
K
V
C
F
I
D
I
D
E
K
R
-
S
A
D
F
----
A
K
E
-
R
P
N
L
F
Y
F
H
G
D
V
A
D
P
L
T
L
K
K
F
V
E
Y
A
M
E
K
L
------
Q
R
I
D
V
L
V
N
N
A
C
R
G
S
K
G
I
L
S
S
L
L
Y
E
E
F
D
Y
I
L
S
V
G
L
K
A
P
Y
E
L
S
R
L
C
R
D
E
L
I
K
-
N
K
G
R
I
I
N
I
A
S
T
R
A
F
Q
S
E
P
D
S
E
A
Y
A
S
A
K
G
G
I
V
A
L
T
H
A
L
A
M
S
L
G
P
-
D
V
L
V
N
C
I
A
P
G
W
I
N
V
T
---
E
F
T
Q
E
------
D
C
A
A
I
P
A
G
K
V
G
T
P
K
D
I
S
N
M
V
L
F
L
C
-
Q
Q
---
D
F
I
T
G
E
T
I
I
V
D
G
G
M
S
-