@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1123: (2016-03-22 )
MKALVLGGSGSIGSEIVKQLLTDGFEVYVQYYRTDINELTSKFNDDKVRFIQADLSQTIDIDKTFGDIKSLDCLIYASGQSLYGVLQDMKDHDIDACYQLNVLQLIRLCRYFVDVLRQSANGRIIVISSIWGETGASMETIYSAMKSAQLGFVKALSQELALTSVTVNAIAPGFVAGNMASEWQEDELQAMITELPQQRLVLPSEVAHTCAYLYHSNARSVTGTIQKVNGAWYI
Atome Classification :
(20 SA)
.........10........20........---------30...--.------....40.------.-----......50.-----...----..----.-.-60...-------..-----..----.----70---.........80..---......90........100.......110.......-120.......130.......140.......150.......160.......170.......180....---------..-..190.......200.......210.......220.......230..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
A
L
V
LGGSG
S
I
G
S
E
I
V
K
Q
L
L
T
D
G
F
E
V
Y
V
---------
Q
Y
Y
R
T
--
D
------
I
N
E
L
T
S
K------F-----NDD
K
V
R
F
I
Q
-----
A
D
L
----
S
Q----
T
-
I
-DI
D
K
T-------FG-----DI----K----S----
L
D
C
L
I
Y
AS
G
Q
S
L
Y
---
G
V
L
Q
D
MKDHD
I
D
A
C
Y
Q
L
N
V
L
Q
L
I
R
L
C
R
Y
F
V
D
V
L
RQS-AN
G
R
I
I
V
I
S
SIWGETGA
S
M
E
T
I
Y
S
A
M
K
S
A
Q
L
G
F
V
K
A
L
S
Q
E
L
A
L
T
S
V
T
V
NAIA
P
G
F
VAGN
M
A
-
S
E
W
Q
E
---------
D
E
-
L
Q
A
M
I
T
EL
P
Q
Q
RLV
L
P
S
E
V
A
H
T
C
A
Y
L
YHSNARSV
T
G
T
I
Q
KVNGAWYI
1
PsiBlast_PDB
88.68
31%
-126
- C1 -
3ENN
-
?
A:
[8-244]
-
K
A
L
V
T
G
A
T
G
G
L
G
E
A
I
A
R
A
L
H
A
Q
G
A
I
V
G
L
---------
H
G
T
R
E
--
E
K
-----
L
K
E
L
A
A
E
------
L
-----
G
E
-
R
I
F
V
F
P
-----
A
N
L
----
S
D
----
R
-
E
-
A
V
-
K
A
-------
L
G
Q
K
A
E
E
E
M
----
G
----
G
----
V
D
I
L
V
N
N
A
G
I
T
R
D
---
G
L
F
V
R
M
S
D
E
D
W
D
A
V
L
T
V
N
L
T
S
V
F
N
L
T
R
E
L
T
H
P
M
M
R
R
-
R
N
G
R
I
I
N
I
T
S
I
V
G
V
T
G
N
P
G
Q
A
N
Y
C
A
S
K
A
G
L
I
G
F
S
K
S
L
A
Q
E
I
A
S
R
N
V
T
V
N
C
I
A
P
G
F
I
E
S
------------------
K
Q
-
K
D
A
I
M
G
N
I
P
M
K
R
M
G
V
G
A
D
I
A
A
A
V
V
Y
L
A
S
D
E
A
A
Y
V
T
G
Q
T
L
H
V
N
G
G
M
A
M
15
PsiBlast_PDB
87.78
29%
-145
- C1 -
3F9I
-
FABG_RICPR
A:
[9-240]
--
S
L
I
T
G
A
S
S
G
I
G
S
A
I
A
R
L
L
H
K
L
G
S
K
V
I
I
---------
S
G
S
N
E
--
E
K
-----
L
K
S
L
G
N
A
------
L
-----
K
D
N
Y
T
I
E
V
------
C
N
L
----
A
N
----
K
-
E
-
E
C
S
N
L
-------
I
S
-----
K
T
----
S
----
N
----
L
D
I
L
V
C
N
A
G
----------------
D
F
D
K
V
I
D
I
N
L
K
A
N
F
I
L
N
R
E
A
I
K
K
M
I
Q
K
-
R
Y
G
R
I
I
N
I
S
S
I
V
G
--
G
N
P
G
Q
A
N
Y
C
A
S
K
A
G
L
I
G
M
T
K
S
L
S
Y
E
V
A
T
R
G
I
T
V
N
A
V
A
P
G
F
I
K
-------
L
N
E
---------
K
Q
-
R
E
A
I
V
Q
K
I
P
L
G
T
Y
G
I
P
E
D
V
A
Y
A
V
A
F
L
A
S
N
N
A
S
Y
I
T
G
Q
T
L
H
V
N
G
G
M
L
M
9
PsiBlast_PDB
81.70
29%
-115
- C1 -
4KMS
-
?
A:
[13-245]
--
A
I
V
T
G
G
T
R
G
I
G
K
A
T
A
L
E
L
K
N
K
G
L
T
V
V
A
---------
N
F
F
S
N
Y
D
A
------
A
K
E
M
E
E
K
------
Y
-----
G
I
K
T
K
C
W
N
V
-----
A
D
F
----
E
E
C
R
Q
A
V
-
K
-
E
I
E
E
E
-------
F
K
-----------
K
----
P
----
V
S
I
L
V
N
N
A
G
I
T
K
D
---
K
M
L
H
R
M
S
H
Q
D
W
N
D
V
I
N
V
N
L
N
S
C
F
N
M
S
S
S
V
M
E
Q
M
R
N
Q
-
D
Y
G
R
I
V
N
I
S
S
I
N
A
---
Q
V
G
Q
T
N
Y
S
A
A
K
A
G
I
I
G
F
T
K
A
L
A
R
E
T
A
S
K
N
I
T
V
N
C
I
A
P
G
Y
I
A
T
E
M
V
----
P
E
---------
D
V
-
L
A
K
I
I
N
S
I
P
K
K
R
L
G
Q
P
E
E
I
A
R
A
V
A
F
L
V
D
E
N
A
G
F
I
T
G
E
T
I
S
I
N
G
G
---
7
PsiBlast_PDB
80.95
30%
-119
- C1 -
4N5N
1
PHBB_CUPNH
A:
[30-269]
--
A
Y
V
T
G
G
M
G
G
I
G
T
A
I
C
Q
R
L
A
K
D
G
F
R
V
V
A
G
C
G
P
NSPR
R
E
K
W
L
E
--
Q
------
Q
K
A
L
G
F
D
------
F
-----
I
A
S
E
G
N
V
A
D
-----
W
D
S
----
T
K
----
T
-
A
--
F
D
K
V
-------
K
S
-----
E
V
----
G
----
E
----
V
D
V
L
I
N
N
A
G
I
T
R
D
---
V
V
F
R
K
M
T
R
A
D
W
D
A
V
I
D
T
N
L
T
S
L
F
N
V
T
K
Q
V
I
D
G
M
A
D
R
-
G
W
G
R
I
V
N
I
S
S
V
N
G
Q
K
G
Q
F
G
Q
T
N
Y
S
T
A
K
A
G
L
H
G
F
T
M
A
L
A
Q
E
V
A
T
K
G
V
T
V
N
T
V
S
P
G
Y
I
A
T
D
M
V
-
K
A
I
R
Q
---------
D
V
-
L
D
K
I
V
A
T
I
P
V
K
R
L
G
L
P
E
E
I
A
S
I
C
A
W
L
S
S
E
E
S
G
F
S
T
G
A
D
F
S
L
N
G
G
L
H
M
5
PsiBlast_PDB
80.59
30%
-120
- C1 -
4N5L
-
PHBB_CUPNH
A:
[30-269]
--
A
Y
V
T
G
G
M
G
G
I
G
T
A
I
C
Q
R
L
A
K
D
G
F
R
V
V
A
G
C
G
PNSPR
R
E
K
W
L
E
--
Q
------
Q
K
A
L
G
F
D
------
F
-----
I
A
S
E
G
N
V
A
D
-----
W
D
S
----
T
K
----
T
-
A
--
F
D
K
V
-------
K
S
-----
E
V
----
G
----
E
----
V
D
V
L
I
N
N
A
G
I
T
R
D
---
V
V
F
R
K
M
T
R
A
D
W
D
A
V
I
D
T
N
L
T
S
L
F
N
V
T
K
Q
V
I
D
G
M
A
D
R
-
G
W
G
R
I
V
N
I
S
S
V
N
G
Q
K
G
Q
F
G
Q
T
N
Y
S
T
A
K
A
G
L
H
G
F
T
M
A
L
A
Q
E
V
A
T
K
G
V
T
V
N
T
V
S
P
G
Y
I
A
T
D
M
V
-
K
A
I
R
Q
---------
D
V
-
L
D
K
I
V
A
T
I
P
V
K
R
L
G
L
P
E
E
I
A
S
I
C
A
W
L
S
S
E
E
S
G
F
S
T
G
A
D
F
S
L
N
G
G
L
H
M
2
PsiBlast_PDB
80.53
32%
-117
- C1 -
3VZQ
-
PHBB_CUPNH
A:
[17-256]
--
A
Y
V
T
G
G
M
G
G
I
G
T
A
I
C
Q
R
L
A
K
D
G
F
R
V
V
A
G
C
G
P
N----
S
P
R
R
E
--
K
------
W
L
E
L
Q
K
A
------
L
-----
G
F
D
---
F
I
A
S
E
G
NV
A
D
W
----
D
S
----
T
K
T
-
A
F
D
K
V
-------
K
S
-----
E
V
----
G
----
E
----
V
D
V
L
I
N
N
A
G
I
T
R
D
---
V
V
F
R
K
M
T
R
A
D
W
D
A
V
I
D
T
N
L
T
S
L
F
N
V
T
K
Q
V
I
D
G
M
A
D
R
-
G
W
G
R
I
V
N
I
S
S
V
N
G
Q
K
G
Q
F
G
Q
T
N
Y
S
T
A
K
A
G
L
H
G
F
T
M
A
L
A
Q
E
V
A
T
K
G
V
T
V
N
T
V
S
P
G
Y
I
A
T
D
M
V
-
K
A
I
R
Q
---------
D
V
-
L
D
K
I
V
A
T
I
P
V
K
R
L
G
L
P
E
E
I
A
S
I
C
A
W
L
S
S
E
E
S
G
F
S
T
G
A
D
F
S
L
N
G
G
L
H
M
10
PsiBlast_PDB
80.16
27%
-131
- C1 -
1I01
-
FABG_ECOLI
A:
[8-241]
--
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
I
G
---------
T
A
T
S
E
--
N
------
G
A
Q
A
I
S
D
------
Y
-----
L
G
A
N
G
K
G
L
M
-----
L
N
V
----
T
D
----
P
-
A
-
S
I
E
S
V
-------
L
E
-----
K
I
----
R
----
A
E
FGE
V
D
I
L
V
N
N
A
--------
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
-
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
--------
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
-
R
A
L
S
D
---------
D
Q
-
R
A
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
S
D
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
--
18
PsiBlast_PDB
80.13
27%
-122
- C1 -
4WK6
1
?
A:
[15-249]
--
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
G
---------
T
A
T
S
E
--
S
------
G
A
Q
A
I
S
D
------
Y
-----
L
G
D
N
G
K
G
M
A
-----
L
N
V
----
T
N
----
P
-
E
-
S
I
E
A
V
-------
L
K
-----
A
I
----
T
D
E
FG
G
----
V
D
I
L
V
N
N
A
G
I
T
R
D
---
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
-
R
Q
G
R
I
I
N
V
A
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
-
K
A
L
N
D
---------
E
Q
-
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
-
4
PsiBlast_PDB
79.79
30%
-116
- C1 -
3VZS
3
PHBB_CUPNH
A:
[17-256]
--
A
Y
V
T
G
G
M
G
G
I
G
T
A
I
C
Q
R
L
A
K
D
G
F
R
V
V
A
G
C
G
P
NSPR
R
E
K
W
L
E
--
Q
------
Q
K
A
L
G
F
D
------
F
-----
I
A
S
E
G
N
V
A
D
-----
W
D
S
----
T
K
----
T
-
A
--
F
D
K
V
-------
K
S
-----
E
V
----
G
----
E
----
V
D
V
L
I
N
N
A
G
I
T
R
D
---
V
V
F
R
K
M
T
R
A
D
W
D
A
V
I
D
T
N
L
T
S
L
F
N
V
T
K
Q
V
I
D
G
M
A
D
R
-
G
W
G
R
I
V
N
I
S
S
V
N
G
Q
K
G
Q
F
G
Q
T
N
Y
S
T
A
K
A
G
L
H
G
F
T
M
A
L
A
Q
E
V
A
T
K
G
V
T
V
N
T
V
S
P
G
Y
I
A
T
D
M
V
-
K
A
I
R
Q
---------
D
V
-
L
D
K
I
V
A
T
I
P
V
K
R
L
G
L
P
E
E
I
A
S
I
C
A
W
L
S
S
E
E
S
G
F
S
T
G
A
D
F
S
L
N
G
G
L
H
M
6
PsiBlast_PDB
79.24
30%
-120
- C1 -
4N5M
4
PHBB_CUPNH
A:
[30-269]
--
A
Y
V
T
G
G
M
G
G
I
G
T
A
I
C
Q
R
L
A
K
D
G
F
R
V
V
A
G
C
G
PNSPR
R
E
K
W
L
E
--
Q
------
Q
K
A
L
G
F
D
------
F
-----
I
A
S
E
G
N
V
A
D
-----
W
D
S
----
T
K
----
T
-
A
--
F
D
K
V
-------
K
S
-----
E
V
----
G
----
E
----
V
D
V
L
I
N
N
A
G
I
T
R
D
---
V
V
F
R
K
M
T
R
A
D
W
D
A
V
I
D
T
N
L
T
S
L
F
N
V
T
K
Q
V
I
D
G
M
A
D
R
-
G
W
G
R
I
V
N
I
S
S
V
N
G
Q
K
G
Q
F
G
Q
T
N
Y
S
T
A
K
A
G
L
H
G
F
T
M
A
L
A
Q
E
V
A
T
K
G
V
T
V
N
T
V
S
P
G
Y
I
A
T
D
M
V
-
K
A
I
R
Q
---------
D
V
-
L
D
K
I
V
A
T
I
P
V
K
R
L
G
L
P
E
E
I
A
S
I
C
A
W
L
S
S
E
E
S
G
F
S
T
G
A
D
F
S
L
N
G
G
L
H
M
3
PsiBlast_PDB
78.95
30%
-117
- C1 -
3VZP
5
PHBB_CUPNH
A:
[17-256]
--
A
Y
V
T
G
G
M
G
G
I
G
T
A
I
C
Q
R
L
A
K
D
G
F
R
V
V
A
G
C
G
P
NSPR
R
E
K
W
L
E
--
Q
------
Q
K
A
L
G
F
D
------
F
-----
I
A
S
E
G
N
V
A
D
-----
W
D
S
----
T
K
----
T
-
A
--
F
D
K
V
-------
K
S
-----
E
V
----
G
----
E
----
V
D
V
L
I
N
N
A
G
I
T
R
D
---
V
V
F
R
K
M
T
R
A
D
W
D
A
V
I
D
T
N
L
T
S
L
F
N
V
T
K
Q
V
I
D
G
M
A
D
R
-
G
W
G
R
I
V
N
I
S
S
V
N
G
Q
K
G
Q
F
G
Q
T
N
Y
S
T
A
K
A
G
L
H
G
F
T
M
A
L
A
Q
E
V
A
T
K
G
V
T
V
N
T
V
S
P
G
Y
I
A
T
D
M
V
-
K
A
I
R
Q
---------
D
V
-
L
D
K
I
V
A
T
I
P
V
K
R
L
G
L
P
E
E
I
A
S
I
C
A
W
L
S
S
E
E
S
G
F
S
T
G
A
D
F
S
L
N
G
G
L
H
M
11
PsiBlast_PDB
78.86
27%
-114
- C1 -
1Q7B
4
FABG_ECOLI
A:
[8-243]
--
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
I
G
---------
T
A
T
S
E
--
N
------
G
A
Q
A
I
S
D
------
Y
-----
L
G
A
N
G
K
G
L
M
-----
L
N
V
----
T
D
----
P
-
A
-
S
I
E
S
V
-------
L
E
-----
K
I
----
R
----
A
E
FGE
V
D
I
L
V
N
N
A
G
I
T
R
D
---
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
-
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
Y
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
-
R
A
L
S
D
---------
D
Q
-
R
A
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
S
D
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
14
PsiBlast_PDB
78.17
28%
-116
- C1 -
3SJ7
3
?
A:
[13-252]
--
A
L
V
T
G
A
S
R
G
I
G
R
S
I
A
L
Q
L
A
E
E
G
Y
N
V
A
V
---------
N
Y
A
G
S
--
K
E
K
A
E
A
V
V
E
E
I
K
A
K
------
G
-----
V
D
S
F
A
--
I
Q
-----
A
N
V
----
A
D
----
A
-
D
-
E
V
K
A
M
-------
I
K
-----
E
V
V
S
Q
F
G
----
S
----
L
D
V
L
V
N
N
A
G
I
T
R
D
---
N
L
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
K
A
T
P
Q
M
L
R
Q
-
R
S
G
A
I
I
N
L
S
S
V
V
G
A
V
G
N
P
G
Q
A
N
Y
V
A
T
K
A
G
V
I
G
L
T
K
S
A
A
R
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
V
S
D
M
T
-----
D
---------
E
L
-
K
E
Q
M
L
T
Q
I
P
L
A
R
F
G
Q
D
T
D
I
A
N
T
V
A
F
L
A
S
D
K
A
K
Y
I
T
G
Q
T
I
H
V
N
G
G
M
Y
M
8
PsiBlast_PDB
78.03
30%
-114
- C1 -
3VZR
-
PHBB_CUPNH
B:
[17-256]
--
A
Y
V
T
G
G
M
G
G
I
G
T
A
I
C
Q
R
L
A
K
D
G
F
R
V
V
A
GCGPNSPRR
E
K
W
L
E
--
Q
------
Q
K
A
L
G
F
D
------
F
-----
I
A
S
E
G
N
V
A
D
-----
W
D
S
----
T
K
----
T
-
A
--
F
D
K
V
-------
K
S
-----
E
V
----
G
----
E
----
V
D
V
L
I
N
N
A
G
I
T
R
D
---
V
V
F
R
K
M
T
R
A
D
W
D
A
V
I
D
T
N
L
T
S
L
F
N
V
T
K
Q
V
I
D
G
M
A
D
R
-
G
W
G
R
I
V
N
I
S
S
V
N
G
Q
K
G
Q
F
G
Q
T
N
Y
S
T
A
K
A
G
L
H
G
F
T
M
A
L
A
Q
E
V
A
S
K
G
V
T
V
N
T
V
S
P
G
Y
I
A
T
D
M
V
-
K
A
I
R
Q
---------
D
V
-
L
D
K
I
V
A
T
I
P
V
K
R
L
G
L
P
E
E
I
A
S
I
C
A
W
L
S
S
E
E
S
G
F
S
T
G
A
D
F
S
L
N
G
G
L
H
M
16
PsiBlast_PDB
77.69
28%
-109
- C1 -
2PH3
-
?
A:
[3-240]
-
K
A
L
I
T
G
A
S
R
G
I
G
R
A
I
A
L
R
L
A
E
D
G
F
A
L
A
I
---------
H
Y
G
Q
N
--
R
------
E
K
A
E
E
V
A
------
E
E
A
R
R
R
G
S
P
L
V
A
V
L
G
-----
A
N
L
LE
A
E
A
A
----
T
-
A
-
L
V
H
Q
A
-------
A
E
-----
V
L
----
G
----
G
----
L
D
T
L
V
N
N
A
G
I
T
R
D
---
T
L
L
V
R
M
K
D
E
D
W
E
A
V
L
E
A
N
L
S
A
V
F
R
T
T
R
E
A
V
K
L
M
M
K
A
-
R
F
G
R
I
V
N
I
T
S
V
V
G
I
L
G
N
P
G
Q
A
N
Y
V
A
S
K
A
G
L
I
G
F
T
R
A
V
A
K
E
Y
A
Q
R
G
I
T
V
N
A
V
A
P
G
F
I
E
T
E
M
T
-
E
R
L
P
Q
---------
E
V
-
K
E
A
Y
L
K
Q
I
P
A
G
R
F
G
R
P
E
E
V
A
E
A
V
A
F
L
V
S
E
K
A
G
Y
I
T
G
Q
T
L
C
V
D
G
----
20
PsiBlast_PDB
77.33
27%
-117
- C1 -
3RRO
11
FABG_VIBCH
A:
[15-250]
--
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
G
---------
T
A
T
S
E
--
S
------
G
A
Q
A
I
S
D
------
Y
-----
L
G
D
N
G
K
G
M
A
-----
L
N
V
----
T
N
----
P
-
E
-
S
I
E
A
V
-------
L
K
-----
A
I
----
T
D
E
FG
G
----
V
D
I
L
V
N
N
A
G
I
T
R
D
---
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
-
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
-
K
A
L
N
D
---------
E
Q
-
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
31
HHSearch
77.19
24%
-131
- C1 -
1O5I
-
?
A:
[20-245]
K
G
V
L
V
L
A
A
S
R
G
I
G
R
A
V
A
D
V
L
S
Q
E
G
A
E
V
T
I
---------
C
A
R
N
E
--
E
------
L
--
L
K
R
---------------
S
G
H
R
Y
V
V
-----
C
D
L
----
R
K
----
D
-
L
D
L
L
F
E
K
-------
V
K
-----
E
---------------
V
D
I
L
V
L
N
A
G
G
P
K
A
---
G
F
F
D
E
L
T
N
E
D
F
K
E
A
I
D
S
L
F
L
N
M
I
K
I
V
R
N
Y
L
P
A
M
K
E
K
-
G
W
G
R
I
V
A
I
T
S
F
S
V
I
S
P
I
E
N
L
Y
T
S
N
S
A
R
M
A
L
T
G
F
L
K
T
L
S
F
E
V
A
P
Y
G
I
T
V
N
C
V
A
P
G
W
T
E
T
E
R
V
K
E
L
L
S
E
---------
E
K
-
K
K
Q
V
E
S
Q
I
P
M
R
R
M
A
K
P
E
E
I
A
S
V
V
A
F
L
C
S
E
K
A
S
Y
L
T
G
Q
T
I
V
V
D
G
G
L
S
-
35
HHSearch
77.02
24%
-116
- C1 -
2CFC
2
HCDR_XANP2
A:
[3-249]
R
V
A
I
V
T
G
A
S
S
G
N
G
L
A
I
A
T
R
F
L
A
R
G
D
R
V
A
A
---------
L
D
L
S
A
--
E
------
T
--
L
E
E
T
A
R
T
HWH
A
-----
Y
A
D
K
V
L
R
V
R
-----
A
D
V
----
A
D
----
E
-
G
-
D
V
N
A
A
I
A
A
T
M
E
Q
F
G
-----
A
---------------
I
D
V
L
V
N
N
A
G
I
T
G
N
SEA
G
V
L
H
T
T
P
V
E
Q
F
D
K
V
M
A
V
N
V
R
G
I
F
L
G
C
R
A
V
L
P
H
M
L
L
Q
-
G
A
G
V
I
V
N
I
A
S
V
A
S
L
V
A
F
P
G
R
S
A
Y
T
T
S
K
G
A
V
L
Q
L
T
K
S
V
A
V
D
Y
A
G
S
G
I
R
C
N
A
V
C
P
G
M
I
E
T
P
M
T
Q
W
R
L
D
Q
---------
P
E
L
R
D
Q
V
L
A
R
I
P
Q
K
E
I
G
T
A
A
Q
V
A
D
A
V
M
F
L
A
G
E
D
A
T
Y
V
N
G
A
A
L
V
M
D
G
A
Y
T
A
36
HHSearch
76.18
26%
-109
- C1 -
3WDS
4
?
A:
[13-261]
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
---------
A
D
L
D
V
--
M
------
A
--
A
Q
A
V
V
A
----
G
-----
L
E
N
G
G
F
A
V
E
-----
V
D
V
----
T
K
----
R
-
A
-
S
V
D
A
A
M
Q
K
A
I
D
A
L
G
-----
G
---------------
F
D
L
L
C
A
N
A
G
V
S
T
M
---
R
P
A
V
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
F
L
A
S
N
T
K
G
V
I
V
N
T
A
S
L
A
A
K
V
G
A
P
L
L
A
H
Y
S
A
S
K
F
A
V
F
G
W
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
F
V
K
T
A
M
Q
E
R
E
I
I
W
E
A
E
L
R
GMT
P
E
A
V
R
A
E
Y
V
S
L
T
P
L
G
R
I
E
E
P
E
D
V
A
D
V
V
V
F
L
A
S
D
A
A
R
F
M
T
G
Q
G
I
N
V
T
G
G
V
R
-
12
PsiBlast_PDB
75.71
26%
-116
- C1 -
1Q7C
1
FABG_ECOLI
A:
[8-243]
--
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
I
G
---------
T
A
T
S
E
--
N
------
G
A
Q
A
I
S
D
------
Y
-----
L
G
A
N
G
K
G
L
M
-----
L
N
V
----
T
D
----
P
-
A
-
S
I
E
S
V
-------
L
E
-----
K
I
----
R
----
A
EFGE
V
D
I
L
V
N
N
A
G
I
T
R
D
---
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
M
M
K
K
-
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
F
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
-
R
A
L
S
D
---------
D
Q
-
R
A
G
I
L
A
Q
V
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
S
D
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M