@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
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Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1267: (2016-03-23 )
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
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380......1390......1400......1410......1420......1430......1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540......1550......1560......1570......1580......1590......1600......1610......1620......1630......1640......1650......1660......1670......1680......1690......1700......1710......1720......1730......1740......1750......1760......1770......1780......1790......1800......1810......1820......1830......1840......1850......1860......1870......1880......1890......1900......1910......1920......1930......1940......1950......1960......1970......1980......1990......2000......2010......2020......2030......2040......2050......2060......2070......2080......2090......2100......2110......2120......2130......2140......2150......2160......2170......2180......2190......2200......2210......2220......2230......2240......2250......2260......2270......2280......2290......2300......2310......2320......2330......2340......2350......2360......2370......2380......2390......2400......2410......2420......2430......2440......2450......2460......2470......2480......2490......2500......2510......2520......2530......2540......2550......2560......2570......2580......2590......2600......2610......2620......2630......2640......2650......2660......2670......2680......2690......2700......2710......2720......2730......2740......2750......2760......2770......2780......2790......2800......2810......2820......2830......2840......2850......2860......2870......2880......2890......2900......2910......2920......2930......2940......2950......2960......2970......2980......2990......3000......3010......3020......3030......3040......3050......3060......3070......3080......3090......3100......3110......3120......3130......3140......3150......3160......3170......3180......3190......3200......3210......3220......3230......3240......3250......3260......3270......3280......3290......3300......3310......3320......3330......3340......3350......3360......3370......3380......--3390......3400......3410......3420......3430......3440......3450......3460......3470......3480......3490......3500......3510--......3520......3530......3540......3550......3560......3570......3580......3590......3600......3610......3620.......3630......3640.--.....3650......3660......3670......3680......3690......3700......3710......3720-......3730......3740......3750......3760......3770.--.....3780......3790......3800......3810......3820------.......3830......3840......3850......3860......3870........3880......3890.....-.3900......-3910......3920......3930-......3940....----..3950......3960......3970....--..3980......3990-----.......4000......4010......4020......4030......4040......4050......4060......4070......4080......4090......4100---.......4110......4120..-....4130......4140..----....4150......4160......4170......4180......4190......4200-.......-----4210......--4220......4230..--....4240.----.....4250......4260......-----4270......4280......4290......4300......4310......4320......4330......4340......4350......4360......4370......4380......4390......4400......4410......4420......4430......4440......4450......4460......4470......4480......4490......4500..---------....4510----.........4520......4530..--....4540......4550......4560......4570......4580......4590......----4600......4610......4620......4630...-------------...4640......4650........4660......4670......4680.----.....4690......4700......4710......4720......4730-------.......4740......4750........4760......4770......4780------.......4790......4800......4810......4820......4830......4840......4850.....-.4860......4870......4880......4890......4900......4910......4920.......4930......4940......4950......4960......4970......4980----.......4990......5000......5010--.........5020......5030-----.......5040......5050......5060......5070......5080......5090......5100......5110......5120......5130......5140......5150......5160......5170......5180......5190......5200......5210......5220......5230......5240......5250......5260......5270......5280......5290......5300......5310......--5320......5330......5340-......5350.--------.....5360......5370......5380......--5390......5400......5410......5420......5430......5440......5450......5460......--5470......5480......5490......5500......5510......5520......5530....-..5540......5550......5560......5570......5580......5590......5600......5610......5620....-..5630......5640......5650......5660......5670......5680......5690......5700......5710......5720......5730......5740......5750......5760.---.....5770......5780.......-..5790......5800......5810......5820......5830....-..5840......5850..-------------....5860......-5870---------......5880......5890..-----.-...5900......5910-----......5920-..-....5930....---..5940....---..---5950----........5960......5970......5980-----...------....5990......6000.......6010......6020.....--.-6030.-----.....6040--...-------------------...-----------.6050......6060...-...6070......6080.--.....6090......6100......6110......6120..--------------....6130......6140...---...6150......6160--.-----........6170......6180......6190......-------6200......6210......6220---........6230......6240......6250......6260......6270......6280......6290......6300......6310......6320....-..6330......6340......6350......6360......6370......6380......6390......6400......6410......6420......6430......6440......6450......6460......6470......6480......6490......6500......6510......6520......6530......6540......6550......6560......6570......6580......6590......6600......6610......6620......6630......6640......6650......6660......6670......6680......6690......6700......6710
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MGNL
Q
T
A
INDKSGTLASQNFL
D
A
D
E
Q
K
R
N
A
Y
N
Q
A
I
S
A
A
E
T
I
L
NKQTGP
N
T
A
K
T
A
V
E
Q
A
L
N
N
V
N
S
A
K
H
ALNGTQNLNNA
K
Q
A
A
I
T
A
INGASDL
N
Q
K
Q
K
D
A
L
K
AQANGAQRVSN
A
N
D
V
Q
R
N
A
T
E
L
N
T
A
M
G
Q
L
Q
H
A
IADKTNTLASSKYVNADSTKQN
A
Y
T
T
KVTN
A
E
H
IISGT
P
T
V
V
TT
P
S
E
V
T
A
A
A
N
Q
V
N
S
A
K
Q
ELN
G
D
E
R
L
R
V
A
KQNA
N
T
A
I
D
A
L
T
QLNT
P
Q
K
A
K
L
K
E
Q
VGQA
N
R
L
E
D
V
Q
S
V
QTN
G
Q
S
L
N
N
A
M
K
G
L
R
D
SIANE
T
T
V
KASQNYTDASPNNQS
T
Y
N
S
A
VSNAKGIINQTNNPTM
D
T
S
A
I
T
Q
A
T
TQVNNAKNGLN
G
A
E
N
L
R
N
A
Q
N
T
A
K
Q
N
L
N
T
L
S
H
L
TN
N
Q
K
S
A
I
S
S
Q
I
DRAGH
V
S
E
V
T
AAKN
A
A
T
E
L
N
A
QMG
N
L
E
Q
A
IH
D
Q
N
T
V
K
QGVNFT
D
A
D
K
A
K
R
D
A
Y
T
N
A
V
S
R
A
E
T
I
L
N
KTQGANT
S
K
Q
D
V
E
A
A
I
Q
N
V
T
S
A
KNALNGDQNVT
N
A
K
N
A
A
K
N
A
L
N
N
L
TSINNAQKR
D
L
T
T
KIDQAT
T
V
A
G
V
E
A
VSNTGT
Q
L
N
T
A
M
A
N
L
Q
NGIND
K
A
N
TLASENYHDADSDKK
T
A
Y
T
Q
AVT
N
A
E
N
I
LNKNSGSNL
D
K
A
A
V
E
N
A
L
S
Q
V
TNAKGALNGNH
N
L
E
Q
AKSNANTTI
N
G
L
Q
H
L
T
T
A
Q
K
D
K
L
K
Q
Q
V
Q
Q
A
QNVAG
V
D
T
V
K
SSANTL
N
G
A
M
G
T
L
R
N
S
IQDNTATKNGQNYLDATERNKTNYNNAVDSAN
G
V
I
NATSNPNM
D
A
N
A
I
N
Q
I
A
T
Q
V
TSTKNALDGTH
N
L
T
Q
A
K
Q
TATNAIDGATNL
N
K
A
Q
K
D
A
L
K
A
Q
V
T
S
A
Q
R
V
A
N
V
T
S
I
Q
Q
T
A
N
E
L
N
T
A
M
G
Q
L
Q
HGIDDENA
T
K
Q
T
Q
K
Y
R
D
A
E
Q
S
K
K
T
A
Y
D
Q
A
V
A
A
A
K
A
I
L
NKQTGSNS
D
K
A
A
V
D
R
A
L
Q
Q
V
T
STKDALNGD
A
K
L
A
E
A
K
A
A
A
R
QNLGT
L
N
H
I
T
N
A
Q
R
T
A
LEGQINQ
A
T
TVDG
V
N
T
VKTNAN
T
L
D
G
A
M
N
S
L
Q
GAINDKDATLRNQNYLDADESKR
N
A
Y
T
Q
A
V
T
A
A
E
G
I
L
NKQTGGNTS
K
A
D
V
D
N
A
L
N
A
V
T
R
A
K
A
ALN
G
A
E
N
L
RNAKTSATNTINGLP
N
L
T
Q
L
Q
K
D
N
L
K
H
Q
V
E
Q
A
Q
N
VVGVNGVKDKGN
T
L
N
T
A
M
G
A
L
R
T
SIQNDNTTKTSQNYLDASDSNKNNYNTAVNNA
N
G
V
I
NATNNPNM
D
A
N
A
I
N
D
M
A
N
QV
N
T
T
K
A
A
L
N
G
A
Q
N
L
A
Q
AKTNATNTIN
N
A
Q
D
L
N
Q
K
Q
K
D
A
L
K
T
QVNNAQRVSDANNV
Q
H
T
A
T
E
L
N
G
A
M
T
A
L
K
A
A
IADKERTKASGNYVN
A
D
Q
E
K
R
Q
A
Y
DSKVT
N
A
E
N
IINGTPN
A
T
L
T
V
ND
V
N
S
A
A
S
Q
V
N
A
A
K
T
ALNGDNN
L
R
V
A
K
E
HANN
T
I
D
G
L
A
Q
LN
N
V
Q
K
A
K
L
K
E
Q
V
Q
SATTLD
G
V
Q
T
VKNS
S
Q
T
L
N
T
A
M
K
G
L
R
D
S
IANE
A
T
IKAGQNYTDASPNNR
N
E
Y
D
S
A
V
T
A
A
K
A
I
I
NQTSNPTMEPN
T
I
T
Q
A
T
SQV
T
T
K
E
HAL
N
G
A
Q
N
L
A
Q
A
K
TTAKNNLNNLTSINN
A
Q
K
D
A
L
TRNIDGA
T
T
V
AGVNQETA
K
A
T
E
L
N
N
A
M
H
S
L
Q
NGIND
E
T
Q
T
K
Q
T
Q
K
Y
LDAEPSKK
S
A
Y
D
Q
A
V
N
A
A
K
A
I
L
TKASGQNV
D
K
A
A
V
E
Q
A
L
Q
N
VNSTKTALNGDAK
L
N
E
A
K
A
A
A
K
Q
T
L
G
T
L
THINNAQRNALD
N
E
ITQATNVEG
V
N
T
V
K
A
K
A
Q
Q
L
D
G
A
M
G
Q
L
E
T
SIRDKDTTLQSQNYQD
A
D
D
A
K
R
T
A
Y
S
Q
A
V
N
A
A
A
T
I
L
NKTAGGNT
P
K
A
D
V
E
R
A
M
Q
A
V
T
Q
A
N
T
A
L
N
G
I
Q
N
L
E
R
A
K
Q
A
ANTAITNASDL
N
T
K
Q
K
E
A
L
K
A
Q
VTSAGRVSAANGV
E
H
T
A
T
E
L
N
T
A
M
T
A
L
K
R
A
I
ADKADTKASG
N
Y
VNADANK
R
Q
A
Y
D
E
K
V
T
A
A
E
H
I
VSGTPTPTL
T
P
S
D
V
T
N
A
A
T
QVTN
A
K
T
Q
LNGNH
N
L
E
V
A
KQNANTAIDGLTSLNG
P
Q
K
A
K
L
K
E
Q
VGQATTLP
N
V
Q
T
V
RD
N
A
Q
T
L
N
T
A
M
K
G
L
R
D
S
IANE
A
T
IKAGQNYTDASQNKQNDYN
N
A
V
T
A
A
K
A
I
IGQTT
S
P
S
M
I
A
Q
E
I
N
Q
A
K
D
Q
V
T
A
K
Q
Q
ALNGQENL
R
T
AQT
N
A
K
Q
H
L
N
G
L
S
D
L
T
N
A
Q
K
D
A
A
K
R
QIEGA
T
H
V
N
E
V
T
Q
AQN
N
A
D
A
L
N
T
A
M
T
N
L
K
NGIQ
D
Q
N
T
I
K
QGVNFT
D
A
D
E
A
K
R
N
A
Y
T
N
A
V
T
Q
A
E
Q
I
L
N
KAQGPNT
A
K
D
G
V
E
T
A
L
Q
N
V
Q
R
A
K
N
ELNGNQNVANA
K
T
T
A
K
N
A
L
N
N
L
TSIN
N
A
Q
K
A
A
L
K
S
QIEGA
T
T
VA
G
V
N
Q
V
S
T
M
A
S
E
L
N
T
A
M
S
N
L
Q
RGI
N
D
E
A
A
T
K
A
A
Q
K
Y
T
E
ADRDK
Q
T
AYN
D
A
V
T
A
A
K
T
L
L
D
KTAGSND
N
K
V
A
V
E
Q
A
L
Q
R
V
N
T
A
K
TALNGDAR
L
N
E
A
K
N
T
A
K
Q
Q
L
A
T
M
S
H
L
TN
A
Q
KA
N
L
T
E
Q
I
ERGTTVAGVQGIQANA
G
T
L
N
Q
A
M
N
Q
L
R
Q
S
I
ASKDATKSSEDYQDANA
D
L
Q
N
A
YNDAVTNAE
G
I
I
SATNNPEM
N
P
D
T
I
N
Q
K
A
S
Q
V
N
S
A
K
SALNG
D
E
K
L
A
A
A
K
Q
T
A
K
S
D
IGRLTDLNNAQRTAANAEVDQAPN
L
A
A
V
TAAKNKAT
S
L
N
T
A
M
G
N
L
K
H
A
LAEKDNTKRSVNYTDADQ
P
K
Q
Q
A
Y
D
T
AV
T
Q
A
E
A
ITNANGSNA
N
E
T
Q
V
Q
A
A
L
N
Q
L
N
Q
A
KNDLNGDN
K
V
A
Q
A
K
E
T
A
K
R
A
L
A
S
YSNLNNAQSTAATSQIDNA
T
T
V
A
D
V
TAAQN
T
A
N
E
L
N
T
A
M
G
Q
L
Q
NGIND
Q
N
T
V
K
Q
QVNFTDADQGKKD
A
Y
TNAVTNA
Q
G
I
L
DKANGQN
M
T
K
A
Q
V
E
A
A
L
N
Q
V
T
TAKNALNGDA
N
V
R
Q
AKSDAKANLGTLTHLNN
A
Q
K
Q
D
L
T
S
Q
IEG
A
T
TVNG
V
N
S
V
K
T
K
A
Q
D
L
D
G
A
M
Q
R
L
E
S
A
IANKDQTKASENYIDADPTKK
T
A
F
D
N
A
I
T
Q
A
E
S
Y
L
NKDHGTN
K
D
K
Q
A
V
E
Q
A
I
Q
S
V
TSTENALNGDAN
L
Q
CAK
T
E
A
T
Q
A
I
D
N
L
T
QLNT
P
Q
K
T
A
L
K
Q
Q
V
N
A
A
Q
R
VSGVTDL
K
N
S
A
T
S
L
N
N
A
M
D
Q
L
K
Q
A
IGDH
D
T
I
V
AGGNYTNASPDKQGAYT
D
A
Y
N
A
A
K
N
IVNGSP
N
V
I
TNA
A
D
V
T
A
A
T
Q
RVNNAETSLNGDT
N
L
A
T
A
K
Q
Q
A
K
D
A
L
R
Q
M
T
H
LS
D
A
Q
K
QSITGQIDSAT
Q
V
T
G
V
QSVKDNAT
N
L
D
N
A
M
N
Q
L
R
N
SIA
N
K
D
EVKASQPYVDADTDKQNAYNTAV
T
S
A
E
N
I
INATSQPTL
D
P
S
A
V
T
Q
A
A
NQVNTNKTALN
G
A
Q
N
L
ANK
K
Q
E
T
T
A
N
I
N
R
L
S
HLNN
A
Q
K
QDLNTQVTNAPNI
S
T
V
N
Q
V
K
T
K
A
E
Q
L
D
Q
A
M
E
R
L
I
N
GIQ
D
K
D
Q
V
K
Q
SVNFTDADPEK
Q
T
AYNN
A
V
T
A
A
E
N
I
I
N
QANGTNA
N
Q
S
Q
V
E
A
A
L
S
T
V
T
T
T
K
Q
ALNGDRKVTDAKNNAN
Q
T
L
S
T
L
D
NLNNAQKGAVTGNIN
Q
A
H
T
V
A
E
V
T
Q
A
I
Q
T
A
Q
E
L
N
T
A
M
G
N
L
K
NSLNDKDTTLGSQNFADADPEK
K
N
A
Y
N
E
A
V
R
N
A
E
N
I
LNKSTGTNV
P
K
D
Q
V
E
A
A
M
N
QVNT
T
K
AALNGT
Q
N
L
E
K
A
K
Q
H
A
N
T
A
I
D
G
L
S
H
L
T
N
A
Q
K
E
A
L
K
Q
L
V
Q
QSTTVAEAQGNEQKAN
N
V
D
A
A
M
D
K
L
R
Q
S
IADNATTKQNQNYTDASPNKKDAYNNA
V
T
T
A
Q
G
I
IDQTTNPSL
D
P
T
V
I
N
Q
AAGQVSTSKNALNGN
E
N
L
E
A
A
K
Q
Q
A
T
Q
S
LGSLDNL
N
N
A
Q
K
Q
A
V
T
NQINGAHTV
D
E
A
N
Q
I
K
Q
N
A
Q
N
L
N
T
A
M
G
N
L
K
Q
A
IADKDAT
K
A
T
V
NFT
D
A
D
Q
A
K
Q
Q
A
YNTAVT
N
A
E
N
I
I
SKANGGNA
T
Q
T
E
V
E
Q
A
I
Q
Q
V
N
A
A
K
Q
ALNGNAN
V
Q
HAKD
E
A
T
A
L
INNSND
L
N
Q
A
Q
K
D
A
L
K
Q
Q
V
QNATTVAG
V
N
--
N
V
K
Q
T
A
Q
E
L
N
N
A
M
T
Q
L
K
Q
GIAD
K
E
QTKADGNFVNADSDK
Q
N
A
Y
N
Q
A
V
A
K
A
E
A
L
ISGTP
D
V
V
V
T
P
S
E
I
T
A
A
L
N
K
V
T
Q
AKNDLNGNTNL
A
T
A
K
Q
N
V
Q
H
A
I
D
QLPNL
N
Q
A
Q
R
D
E
Y
S
K
Q
I
T
Q
A
TLVP
N
--
V
N
A
I
Q
Q
A
A
T
T
L
N
D
A
M
T
Q
L
K
Q
GIAN
K
A
Q
IKGSENYHDADTDKQTAYD
N
A
V
T
K
A
E
E
L
L
K
QTTNPTM
D
P
N
T
I
Q
Q
A
L
T
KVNDTNQALNGNQKLA
D
A
K
Q
D
A
K
T
TLG
T
L
D
H
L
N
-
D
A
Q
K
Q
A
L
T
T
Q
V
EQAPDI
A
T
V
N
N
V
K
--
Q
N
A
Q
N
L
N
N
A
M
T
N
L
N
N
A
L
Q
D
K
T
E
TLNSINFTDADQAKKDDY
T
N
A
V
S
H
A
E
G
I
L
SKANGSNA
S
Q
T
E
V
E
Q
A
M
Q
R
V
N
E
A
K
Q
ALN-GND
N
V
Q
R
A
K
D
A
A
K
Q
V
ITNA
N
D
L
N
Q
A
Q
K
D
A
L
K
Q
Q
V
D
A
A
Q
T
V
A
N
V
N
T
I
K
Q
T
A
Q
--
D
L
N
Q
A
M
T
Q
L
K
Q
GIADKDQTKANG
N
F
VNADTDKQNAYN
N
A
V
A
H
A
E
Q
I
IS-------GTPNANV
D
P
Q
Q
V
A
Q
A
L
Q
Q
V
N
Q
AKGDLNGNH
N
L
Q
V
AKDNAN
T
A
I
DQLPNL--NQ
P
Q
K
T
A
L
K
D
Q
V
S
H
A
E
L
V
T
G
V
N
A
I
K
Q
N
-
A
D
A
L
N
N
A
M
G
T
L
-
K
Q
Q
I
Q
ANSQVPQSVDFTQA
D
Q
D
K
Q
-
Q
A
Y
N
N
A
A
N
Q
A
Q
Q
I
A----NGTPT
P
V
LA
P
D
T
V
T
K
A
V
T
T
M
N
Q
A
K
DALN
G
D
--
E
K
L
A
Q
A
K
Q
D
A
L
A
N
L
D
------
T
L
R
DLNQ
P
Q
R
D
A
L
R
N
Q
I
N
Q
A
Q
A
L
A
T
V
E
Q
T
K
Q
N
AQ
N
V
N
T
A
M
G
N
L
K
Q
GIANKDTVKASENYHDADVD
K
Q
T
A
Y
T
N
A
V
S
Q
A
E
G
I
I
NQTTNPTL
N
P
D
D
I
T
R
A
L
T
Q
V
TDAKNSLNG----E
A
K
L
ATEKQN
A
K
D
A
V
SGMTH
L
N
D
-
A
Q
K
Q
A
LKGQIDQSPE
I
A
T
V
N
----
Q
V
K
Q
T
A
T
S
L
D
Q
A
M
D
Q
L
S
Q
AIND
K
D
Q
I
LADGNYLNADPD
K
Q
N
A
Y
K
Q
A
V
A
K
A
E
A
L
L
NKQ--SG
T
N
E
V
Q
-----
A
Q
V
E
S
I
T
N
E
V
--
N
A
A
K
Q
ALNGNDNL
A
N
A
--
K
Q
Q
A
K
Q
Q
L
A
----
N
LTHL
N
D
A
Q
K
Q
S
F
E
S
Q
ITQAPLVT
D
-----
V
T
T
I
N
Q
K
A
Q
T
L
D
H
A
M
E
L
L
R
N
SVADNQTTLASEDYH
D
A
T
A
Q
R
QNDY
N
K
A
V
T
A
A
N
N
I
I
NQTTSPTMNPDDVNGA
T
T
Q
VNN
T
K
V
A
LDGD
E
N
L
A
A
A
K
Q
Q
A
NNR
L
D
Q
L
D
HL
N
N
A
Q
K
Q
Q
L
Q
S
Q
ITQSS
D
I
A
A
VNGH
K
Q
T
A
E
S
L
N
T
A
M
G
N
L
I
N
A
I
A
D
H
Q
A
V
E
Q
RGNFINADTDKQ
T
A
Y
N
T
A
V
N
E
A
A
A
M
I
N
KQTGQNA
N
Q
T
E
V
E
Q
A
I
T
K
V
Q
T
T
L
Q
A
LNGDH
N
L
Q
V
A
KTNA
T
Q
A
I
D
V
L
TSLND
P
Q
---------
K
T
A
L
K
-------
D
Q
V
T
A
A
T
L
V
T
A
V
H
Q
I
E
Q
N
A
N
T
L
N
Q
A
--
M
H
G
L
R
Q
S
I
Q
DNAATKANSKYINEDQPEQ
Q
N
Y
D
Q
A
V
Q
A
A
N
N
I
INEQTATLDN
N
A
I
N
Q
V
A
A
TVNT
T
----
K
A
A
L
H
G
D
V
K
LQN
D
K
D
H
A
K
Q
T
V
S
Q
L
A
H
L
N
N
A
Q
K
H
M
E
D
T-------------LIDS
E
T
T
R
T
A
V
K
Q
D
L
--
T
E
V
Q
A
L
D
Q
L
M
D
A
L
Q
Q
S
IAD
K
D
ATRAS
S
A
Y
VNAE----PN
K
K
Q
A
Y
D
E
A
V
Q
N
A
E
S
I
I
AGLNNPTINKGN
V
S
S
A
T
Q
A
V
I
SSKN
A
L
D
G
V
--------
E
R
L
A
Q
D
K
Q
TAGNSL
N
H
L
D
Q--LT
P
A
Q
Q
Q
A
L
E
N
Q
INNAT
T
R
D
K
V
A
E
I
I
A
Q
A
Q
A
-------
L
N
E
A
M
K
A
L
K
E
S
IKDQPQT
E
A
S
SKFIN
E
D
Q
A
Q
K
D
A
Y
T
Q
A
V
Q
H
A
K
D
L
I
NKTT
D
P
T
L
A
K
S
I
I
D
Q
A
T
Q
A
V
T
DAKNNLHG
D
-
Q
K
L
A
Q
D
K
Q
R
A
T
E
T
L
N
N
L
SNLNT
P
Q
R
Q
A
L
E
N
Q
INNAA
T
R
G
E
V
A
Q
K
L
T
E
A
Q
A
L
N
Q
A
M
E
A
L
R
N
S
I
Q
-
D
Q
Q
QTESGSKFINEDKP
Q
K
D
A
Y
Q
A
A
V
Q
N
A
K
D
L
I
NQTGNPTL
D
K
A
Q
V
E
Q
L
T
H
A
F
K
Q
A
K
DNLH-----GDQKLADD
K
Q
H
A
V
T
D
L
N
Q
LNGLN
N
P
Q
R
Q
-----
A
L
E
S
Q
I
NNAA
T
R
G
E
V
A
Q
K
L
A
E
A
------
K
A
L
D
Q
A
M
Q
A
L
R
N
S
I
Q
D
Q
Q
Q
T
E
AGSKFINEDKP
Q
K
D
A
Y
Q
A
A
V
Q
N
A
K
D
L
I
NQTGNPTL
D
K
S
Q
V
E
Q
L
T
Q
A
V
T
T
AKDNLH
G
D
Q
K
L
A
R
D
Q
Q
Q
A
V
T
T
V
NALPNL
N
H
A
Q
Q
Q
T
L
T
D
A
INAAP
T
R
T
E
V
A
Q
H
V
Q
T
A
T
E
L
D
H
A
M
E
T
L
K
N
K
V
DQVNTDKAQPNYTEAST
D
K
K
E
A
V
D
Q
A
L
Q
A
A
Q
SITDPTNGSNA
N
K
D
A
V
E
Q
A
L
T
K
L
Q
E
K
V
N
ELNGN
E
R
V
A
E
A
K
T
Q
A
K
Q
T
I
D
Q
L
THL
N
A
D
Q
I
A
T
A
K
Q
N
I
D
Q
A
TKL
Q
P
I
A
E
L
V
D
Q
A
T
Q
L
N
Q
S
M
D
Q
L
Q
Q
A
V
N
EHA
N
V
E
Q
T
I
DYTQAD
S
D
K
Q
K
--
A
Y
K
Q
A
I
A
D
A
E
N
V
L
K
QNA
N
K
Q
Q
V
D
Q
-
A
L
Q
N
I
L
N
A
K
Q
A--------LNGD
E
R
V
A
L
AKTNGKH
D
I
D
Q
L
N
A
LNNAQQDGFKGR--IDQSN
D
L
N
Q
I
Q
Q
I
V
D
E
A
K
A
L
N
R
A
M
D
Q
L
S
Q
E
ITGNEGRTKGSTNYVNA
D
T
Q
V
K
Q
V
Y
D
E
A
V
D
K
A
K
Q
A
L
D
KSSGQNL
T
A
E
Q
V
I
--KLN
D
A
V
T
A
A
K
K
ALN
G
E
E
R
LN
N
R
K
A
E
A
L
Q
R
L
D
Q
L
T
HLN
N
A
Q
R
Q
L
A
I
Q
QIN
N
A
E
T
L
N
K
A
S
R
A
I
N
R
A
T
K
L
D
-
N
A
M
G
A
V
Q
Q
Y
I
D
E
Q
HL
G
V
ISST
N
Y
INADDNLKANYD
N
A
I
A
N
A
A
H
E
L
D
K
VQGNAI
A
K
A
E
A
E
Q
L
K
Q
N
I
I
D
A
Q
NALNGDQNLANA
K
D
K
A
N
A
F
V
N
-
S
LNGL
N
Q
Q
Q
Q
D
L
A
H
K
AINNAD
T
V
S
D
V
T
D
I
VNNQID
L
N
D
A
M
E
T
L
K
H
L
VDNEIP
N
A
E
Q
T
V
NYQNADDNAKT
N
F
D
D
A
K
R
L
A
N
T
L
LNSDNTNV
N
D
I
N
G
A
I
Q
A
V
N
D
A
I
HNLN
G
D
Q
R
L
Q
D
A
K
D
K
A
I
Q
S
I
N
Q
A
L
A
N
K
L
K
E
I
EAS---NAT
D
Q
D
K
L
I
A
K
N
K
A
E
E
---
L
A
N
S
I
I
N
-
N
I
N
KATS
N
Q
A
V
S
Q
V
Q
T
AG
N
H
A
I
E
Q
V
H
ANEIPKAKIDANK
D
V
D
K
Q
V
Q
A
L
I
D
-
E
IDRNPNL
T
D
K
E
K
Q
A
L
K
D
-------------
R
I
N
Q
I
L
Q
QGH
N
D
I
N
-
N
AL
T
---------
K
E
E
I
E
Q
A
K
A
Q
L
A
Q
A
L
Q
D
I
K
D
L
V
-----
K
-
A
K
E
D
A
K
Q
D
V
D
K
Q
V
Q
A
L
I
-----
D
E
IDQNPNL
T
-
D
K
-
E
K
Q
A
L
K
D
R
I
N
Q
I
---
L
Q
QGHNGINN---AM---
T
K
------
E
E
I
E
Q
A
K
A
Q
L
A
Q
A
L
K
E
I
K
D
L
V
K
A
KEN
A
K
Q
D
V
------
D
K
Q
------
V
Q
A
L
I
D
E
IDQNPNL
T
D
K
-
E
K
Q
A
L
K
D
R
I
N
Q
I
L
Q
QGHN
D
I
N
N
A
M
T
K
--
E
-
E
I
E
Q
A
-----
K
A
Q
L
A
Q
A
L
---
Q
D
I
-------------------
K
D
L
-----------
V
K
A
K
E
D
A
K
N
A
I
K
A
L
A
N
A
K
-RDQINSNPDL
T
P
E
Q
K
A
K
A
--
L
K
E
I
D
E
A
E
K
R
A
L
Q
NVE
N
A
Q
T
I
D
Q
L
N
RGLNL
G
L
D
DIRNT
H
V
W
--------------EVDEQP
A
V
N
E
I
F
EATP
E
Q
I
L
V---N
G
E
L
I
V
HRDDII
T
E
-----
Q
-----
D
I
L
A
H
I
N
L
I
D
Q
L
S
A
E
VIDTPSTATISDS
L
T
A
K
V
E
V
T
L
L-------DG
S
K
V
I
V
NV
P
V
K
V
V
E
K
E
L
S
V
V
K
-----
Q
Q
A
I
E
S
I
E
N
A
A
Q
Q
K
I
D
E
INN
S
V
T
L
T
L
E
Q
K
E
A
A
I
A
E
V
N
K
L
K
Q
Q
A
I
D
HVNNAPDV
H
S
V
E
E
I
Q
Q
Q
E
Q
A
Y
I
E
QFNPE
Q
F
T
I
E
Q
A
KS
N
A
I
K
S
I
E
D
A
I
Q
H
M
I
D
E
I
K
ARTDLT-
D
K
E
K
Q
E
A
I
A
K
L
N
Q
L
K
E
Q
A
I
Q
A
I
Q
R
A
Q
S
I
S
E
I
T
E
Q
L
E
Q
F
K
A
Q
MKAAN
P
T
A
K
E
L
A
K
R
K
Q
E
A
I
S
R
I
K
D
F
S
N
E
K
I
N
S
IRNSEIGT
A
D
E
K
Q
A
A
M
N
Q
I
N
E
I
V
L
E
T
I
R
D
I
N
N
A
H
T
L
Q
Q
V
E
A
A
L
NNGI
A
R
I
S
A
V
Q
I
V
I
SDRAKQSSSTGNESN
S
H
L
T
I
G
Y
GTANHPFNSSTIGHKKKLDEDDDI
D
P
L
H
M
R
H
F
S
N
N
F
G
N
V
I
K
N
A
I
G
V
V
G
I
S
G
L
L
A
S
F
W
F
F
I
A
K
R
RRKED
E
E
E
E
L
E
IRDN
N
K
D
S
I
K
E
T
L
DDTKH
L
P
L
L
F
A
K
R
RRKEDEEDVTVEEKDSLNNGES
L
D
KVKHTPFFL
P
K
RRRKEDEED
V
E
VTNENTD
E
K
V
LKDNEHSPL
L
F
A
K
RRKD
K
E
EDVETTTSIESKDEDV
P
L
L
L
AKKKNQKDNQSKDKKSASKN
T
S
K
K
V
A
A
K
K
K
K
K
KSKKNKK
12
HHSearch
75.55
51%
220
- C5 -
2DGJ
2
EBHA_STAAM
A:
[2-249]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
M
G
Q
L
Q
H
G
I
D
D
E
N
A
T
K
Q
T
Q
K
Y
R
D
A
E
Q
S
K
K
T
A
Y
D
Q
A
V
A
A
A
K
A
I
L
N
K
Q
-----
D
K
A
A
V
D
R
A
L
Q
Q
V
T
S
T
K
D
A
L
N
G
D
A
K
L
A
E
A
K
A
A
A
R
Q
N
L
G
T
L
N
H
I
T
N
A
Q
R
T
A
L
E
G
Q
I
N
Q
A
T
T
V
D
G
V
N
T
V
K
T
N
A
N
T
L
D
G
A
M
N
S
L
Q
G
A
I
N
D
K
D
A
T
L
R
N
Q
N
Y
L
D
A
D
E
S
K
R
N
A
Y
T
Q
A
V
T
A
A
E
G
I
L
N
K
Q
T
G
G
N
T
S
K
A
D
V
D
N
A
L
N
A
V
T
R
A
K
A
A
L
N
G
A
E
N
L
R
N
A
K
T
S
A
T
N
T
I
N
G
L
P
N
L
T
Q
L
Q
K
D
N
L
K
H
Q
V
E
Q
A
Q
N
V
V
G
V
N
G
V
K
D
K
G
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
74.32
99%
208
- C5 -
2DGJ
2
EBHA_STAAM
A:
[2-249]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
M
G
Q
L
Q
H
G
I
D
D
E
N
A
T
K
Q
T
Q
K
Y
R
D
A
E
Q
S
K
K
T
A
Y
D
Q
A
V
A
A
A
K
A
I
L
N
K
Q
-----
D
K
A
A
V
D
R
A
L
Q
Q
V
T
S
T
K
D
A
L
N
G
D
A
K
L
A
E
A
K
A
A
A
R
Q
N
L
G
T
L
N
H
I
T
N
A
Q
R
T
A
L
E
G
Q
I
N
Q
A
T
T
V
D
G
V
N
T
V
K
T
N
A
N
T
L
D
G
A
M
N
S
L
Q
G
A
I
N
D
K
D
A
T
L
R
N
Q
N
Y
L
D
A
D
E
S
K
R
N
A
Y
T
Q
A
V
T
A
A
E
G
I
L
N
K
Q
T
G
G
N
T
S
K
A
D
V
D
N
A
L
N
A
V
T
R
A
K
A
A
L
N
G
A
E
N
L
R
N
A
K
T
S
A
T
N
T
I
N
G
L
P
N
L
T
Q
L
Q
K
D
N
L
K
H
Q
V
E
Q
A
Q
N
V
V
G
V
N
G
V
K
D
K
G
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
63.76
14%
45
* C6 *
3VKG
7
?
A:
[47-3244]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
D
S
L
K
E
T
A
W
S
A
I
I
P
A
F
D
H
A
Q
N
L
I
K
I
Y
L
K
G
N
A
I
I
T
D
L
H
S
E
A
I
K
D
R
H
W
K
I
L
K
K
R
L
N
T
N
W
I
I
T
E
L
T
L
G
S
I
W
D
S
D
L
A
R
N
E
N
I
Y
R
E
V
I
T
A
A
Q
G
E
I
A
L
E
E
F
L
K
G
V
R
E
F
W
T
T
L
E
L
D
L
V
N
Y
Q
----
R
K
C
K
L
V
R
G
W
D
D
L
F
N
K
L
A
E
H
L
N
S
I
S
A
M
K
M
S
P
Y
Y
----
K
V
F
E
E
E
A
N
H
W
D
D
R
L
N
K
V
R
S
L
L
D
V
W
I
D
V
Q
R
R
W
V
Y
L
E
G
I
F
I
N
QL
L
P
A
E
S
T
R
F
K
S
I
N
S
E
F
I
A
I
L
K
K
V
S
G
A
P
L
I
L
E
V
L
A
I
-
E
R
I
Q
Q
T
M
E
R
L
S
D
L
L
G
K
V
Q
K
A
L
G
E
Y
L
E
R
Q
R
S
A
-
F
A
R
F
Y
F
V
G
D
E
D
L
L
E
I
I
G
N
S
K
D
I
I
K
I
Q
K
H
F
R
K
M
F
A
G
L
A
N
L
T
L
D
D
E
K
T
T
I
I
G
M
S
S
A
E
G
E
T
V
T
F
K
K
P
I
S
I
A
N
G
P
K
I
H
E
W
L
T
M
V
E
S
E
M
K
S
T
L
A
T
L
L
S
E
S
L
Q
H
F
N
Q
V
D
V
N
D
H
S
K
Y
S
E
W
V
D
N
-------
Y
P
T
Q
L
V
L
L
T
S
Q
I
V
W
S
T
Q
V
D
Q
A
L
G
G
G
T
L
Q
Q
S
K
I
Q
E
Q
L
Q
S
I
E
Q
T
T
Q
M
I
L
N
N
L
A
D
S
V
L
Q
D
L
S
A
Q
K
R
K
K
F
E
H
L
I
T
E
L
V
H
Q
R
D
V
V
R
Q
L
Q
K
C
K
N
L
T
G
N
K
D
F
D
W
L
Y
H
M
R
Y
Y
Y
D
A
T
Q
E
N
V
L
H
K
L
V
I
H
M
A
N
A
T
F
Y
YGFEYL
G
I
G
E
R
L
V
Q
T
P
L
T
D
R
C
Y
L
T
L
T
Q
A
L
E
S
R
M
G
G
N
P
F
G
P
A
G
T
G
K
T
E
T
V
K
A
L
G
S
Q
L
G
R
F
V
L
V
F
C
C
D
E
G
F
D
L
Q
A
M
S
R
I
F
V
G
L
C
Q
C
G
A
W
G
C
F
D
E
F
N
R
L
E
E
R
I
L
S
A
V
S
Q
Q
I
Q
T
I
Q
V
A
L
K
E
N
S
K
E
V
E
L
L
N
I
S
L
H
Q
D
M
G
I
F
V
T
M
N
P
G
Y
A
G
R
S
N
L
P
D
N
L
K
K
L
F
R
S
M
A
M
I
K
P
---
D
R
--
E
M
I
A
Q
V
M
L
Y
S
-
Q
G
F
K
------
T
A
E
V
L
A
G
K
I
V
P
L
F
K
L
C
Q
E
Q
L
S
A
Q
S
H
Y
D
F
G
L
R
A
L
K
S
V
L
V
S
A
G
G
I
K
R
K
C
Q
P
P
D
-------
A
E
S
K
T
K
A
D
Q
I
Y
C
Q
Y
E
I
G
V
L
L
N
S
I
N
D
T
M
I
P
K
L
V
A
D
D
I
P
L
I
Q
S
L
L
L
D
V
---
F
P
G
----
S
Q
L
Q
P
I
Q
M
D
Q
L
R
K
K
I
Q
E
I
A
K
Q
R
H
L
V
T
K
Q
E
W
V
E
K
I
L
Q
L
H
Q
I
L
N
I
N
H
G
V
M
M
V
G
P
S
G
G
G
K
T
T
S
W
E
V
Y
L
E
A
I
E
Q
V
D
N
I
K
S
E
A
H
V
M
--
D
P
-------
K
A
I
T
K
D
Q
L
F
G
S
L
D
--
L
T
T
R
E
W
T
D
G
L
F
T
A
T
L
R
R
I
I
D
N
V
RG
E
S
T
K
R
H
W
I
I
F
D
G
D
V
D
P
--
E
W
V
E
N
L
N
S
L
LDDN
K
L
L
T
L
P
N
G
E
R
L
A
L
P
N
N
V
R
V
M
F
E
V
Q
D
LKYAT
L
A
T
I
S
R
C
G
M
V
W
F
S
E
E
I
L
T
T
Q
M
I
F
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N
Y
L
D
T
L
S
N
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P
F
D
P
Q
E
K
E
Q
Q
K
R
N
E
N
A
I
P
A
G
L
K
V
Q
K
E
C
A
A
I
I
S
Q
Y
F
E
P
G
G
----
L
V
H
K
V
L
E
D
A
G
Q
R
P
H
I
M
D
F
T
R
L
R
V
L
N
S
F
F
S
L
M
N
R
S
I
V
N
V
I
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Y
N
Q
L
H
S
D
F
P
-
M
S
P
E
N
Q
S
N
Y
I
T
N
R
L
L
Y
S
L
M
W
G
L
G
G
S
M
G
L
V
E
R
E
N
F
--
S
K
F
I
Q
T
I
A
I
T
P
V
P
A
N
T
I
P
L
L
D
Y
S
V
S
I
D
D
A
N
W
S
L
W
K
N
K
V
E
V
E
T
H
K
V
A
---
S
P
D
V
V
I
P
T
V
D
T
T
R
H
V
D
V
L
H
A
W
L
S
E
H
---------
R
P
L
I
L
C
G
P
PGSG
K
T
M
T
L
T
S
T
L
R
A
F
P
D
F
E
V
V
S
L
N
F
S
S
A
TT
P
E
L
L
L
K
T
F
D
H
H
C
E
Y
K
R
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P
S
G
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T
V
L
R
P
T
Q
L
G
K
W
L
V
V
F
C
D
E
--
I
N
--
L
P
S
T
D
K
Y
G
T
Q
R
V
I
T
F
I
R
Q
M
----
V
E
K
--
G
G
F
W
R
T
S
D
H
T
W
I
K
L
D
K
I
Q
F
V
G
A
C
N
P
P
T
D
A
G
R
V
QLTHRFLRH
A
P
I
L
L
V
D
F
P
S
T
S
S
L
T
Q
I
Y
G
--
T
F
N
R
A
L
M
K
L
L
P
N
L
R
-
S
F
A
D
N
L
T
D
A
M
V
E
F
Y
S
E
S
Q
K
R
F
T
P
D
I
Q
A
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P
R
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L
S
R
W
D
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A
L
L
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A
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Q
T
M
D
G
C
T
L
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G
L
V
R
L
W
A
H
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A
L
R
L
F
QDRLVE
T
E
E
K
E
W
T
D
K
K
I
D
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A
L
K
H
F
P
S
VN
L
D
A
L
K
R
P
I
L
Y
S
N
W
L
T
P
V
N
R
S
D
L
R
E
Y
V
K
A
R
L
K
V
F
YPLVL
F
N
E
V
L
D
H
I
L
R
I
D
R
V
F
R
Q
P
Q
G
H
A
L
L
I
G
V
S
G
G
G
K
S
V
L
S
R
F
V
A
W
M
N
G
L
----------------
S
I
Y
T
I
K
Y
K
S
S
D
F
D
D
D
L
R
M
L
L
K
R
A
G
C
K
E
E
K
I
C
F
I
F
D
E
S
N
V
L
E
S
S
F
L
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R
M
N
T
L
L
A
G
G
E
V
P
-
G
L
F
E
G
E
E
F
T
A
L
M
H
A
C
K
E
T
A
Q
-
R
-----
N
G
L
I
L
D
S
E
E
E
L
Y
K
Y
F
T
S
Q
V
R
R
N
L
H
V
V
F
T
M
N
P
A
----
S
P
D
F
H
N
S
P
A
L
F
N
R
C
V
L
D
W
F
-----
G
E
W
S
P
E
A
L
F
Q
V
G
S
E
F
T
R
N
L
D
-
L
E
N
P
Q
Y
I
-----
A
P
P
V
F
I
Q
E
A
E
I
L
M
A
I
--
P
P
S
H
R
------
D
A
V
V
S
S
L
V
Y
I
H
Q
T
I
-
G
E
A
N
I
R
L
L
K
R
Q
G
R
Q
N
Y
V
T
P
R
H
Y
L
D
F
I
N
Q
V
V
L
L
I
N
E
------
K
R
D
Q
L
E
E
E
Q
L
H
L
N
I
G
L
K
K
L
R
D
T
E
A
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V
K
D
L
Q
V
S
L
A
Q
K
N
R
E
L
D
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K
N
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A
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L
K
Q
M
V
Q
D
Q
Q
A
A
E
I
K
Q
K
D
A
R
E
L
Q
V
Q
L
D
V
R
N
K
E
I
A
V
Q
K
V
K
A
Y
A
D
L
P
L
R
E
E
V
E
Q
L
E
N
A
A
N
E
L
K
L
K
Q
D
E
I
V
A
T
I
T
A
L
E
K
S
I
A
T
Y
K
E
E
Y
A
T
L
I
R
E
---
T
E
Q
I
K
T
E
S
S
K
V
K
N
K
V
D
R
S
I
A
L
L
D
N
L
N
S
E
R
G
R
W
E
Q
Q
S
E
N
F
N
T
Q
M
S
T
V
V
G
D
V
V
L
A
S
A
F
L
A
Y
I
G
F
F
D
Q
N
F
R
T
D
L
M
R
K
W
M
I
R
L
D
S
V
G
I
K
F
K
S
DL
S
V
P
S
F
L
S
K
P
E
E
R
L
N
W
H
A
N
S
L
P
S
D
E
L
C
I
E
N
A
I
M
L
K
R
F
NRYPLVID
P
S
G
Q
A
M
E
F
L
M
N
Q
Y
A
D
K
K
I
T
K
T
S
F
M
K
N
L
E
S
A
L
R
F
G
C
P
L
L
V
Q
D
V
E
S
F
M
I
F
L
F
T
R
D
P
T
A
H
F
T
--
P
D
L
C
S
R
V
T
F
V
N
F
T
V
T
P
S
S
L
Q
S
Q
C
L
H
E
A
L
K
T
E
R
P
D
T
H
K
K
R
S
D
L
L
K
I
Q
G
E
F
Q
V
K
L
R
I
L
E
K
S
L
L
N
A
L
S
Q
A
S
G
N
I
L
D
D
D
S
V
I
S
T
-
L
E
T
L
K
K
E
T
T
E
I
A
L
K
V
E
E
T
E
T
V
M
Q
E
I
S
E
V
S
A
L
--
Y
N
P
M
A
L
S
C
S
R
V
Y
-
F
A
M
E
E
L
S
Q
F
----
H
L
Y
Q
F
S
L
R
A
F
L
D
I
F
Y
N
L
L
N
N
N
P
N
L
V
D
K
------
K
D
P
N
E
R
L
V
Y
L
S
K
D
I
F
S
M
T
F
N
R
V
T
R
T
L
L
N
D
D
K
L
T
F
A
L
Q
L
T
I
I
S
V
K
G
T
S
N
E
I
E
E
S
E
W
D
F
L
L
K
G
G
D
N
L
T
S
I
K
E
T
I
P
Q
L
D
S
L
--
L
S
T
T
Q
Q
K
W
L
I
C
L
R
Q
Q
V
P
S
F
S
K
L
V
D
H
I
Q
Q
N
S
S
D
W
K
Q
F
F
G
K
D
Q
V
G
E
P
I
I
P
E
S
W
I
V
A
Q
A
Q
L
S
N
Q
Q
--
S
T
I
V
S
N
F
R
K
I
L
L
M
K
A
F
H
S
D
R
V
L
Q
Y
S
H
S
F
V
C
S
V
F
G
E
D
F
L
---
N
T
L
D
M
A
N
I
V
E
K
E
V
K
S
S
S
P
L
L
L
C
S
V
P
G
Y
D
A
S
S
K
V
D
D
L
A
L
Q
L
H
K
Q
Y
K
S
F
A
I
G
S
P
E
G
F
E
L
A
E
K
S
I
Y
A
A
A
K
S
G
T
--
W
V
L
L
K
-
N
I
H
L
A
P
Q
W
L
V
Q
L
E
K
K
L
H
S
L
S
P
H
PS
F
R
L
F
M
T
S
E
I
H
P
A
L
P
A
N
L
L
R
M
S
-
N
V
F
S
---------
Y
E
N
P
P
G
V
K
A
N
L
L
H
T
F
I
G
I
P
--------------------------
A
-----
T
R
M
D
K
Q
P
----------
A
E
R
S
R
I
Y
F
L
---
L
A
W
F
H
A
I
I
Q
E
---
R
L
---
R
Y
IPLGWT
K
F
F
E
F
N
D
A
D
L
R
G
A
L
D
S
I
D
Y
W
V
D
L
Y
S
K
G
R
S
N
I
------
D
P
D
KIP
W
I
A
V
R
T
I
L
G
S
T
I
Y
G
G
R
I
D
N
E
F
D
M
R
L
L
Y
S
F
L
E
Q
L
F
T
P
S
A
F
N
P
D
F
P
L
V
P
--
S
-
I
G
L
S
V
P
E
G
TT
R
A
H
F
M
K
W
I
---
E
A
L
-------------------
P
E
I
STPIWLGLPEN
A
E
S
L
L
L
S
N
K
A
R
K
M
I
N
D
L
Q
-
K
M
Q
S
S
E
E
D
S
S
S
S
E
D
K
G
K
A
KP
L
F
R
C
F
E
R
E
I
S
T
G
G
K
L
V
K
K
I
T
N
D
L
A
N
L
L
K
W
Y
S
V
P
E
T
I
S
L
S
V
W
--------------
I
S
D
F
S
K
R
M
Q
Q
L
S
E
I
S
E
S
V
W
L
G
GLL
N
P
E
A
Y
I
T
A
T
R
Q
S
A
S
-----
Q
L
NGRL
H
A
S
A
S
F
N
V
K
G
M
A
L
E
G
A
V
W
N
N
D
Q
L
T
P
T
D
I
L
S
T
P
I
S
I
A
T
L
T
W
K
DPIF
N
N
S
S
S
K
L
S
V
P
V
Y
L
N
E
T
R
S
E
L
L
F
-----
S
I
D
L
P
Y
D
Q
S
T
S
K
Q
N
W
Y
Q
R
S
V
S
I
S
S
W
K
S
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
56.75
96%
479
- C5 -
4KJM
11
EBH_STAAT (first)
A:
[5-128]
-
G
N
L
Q
T
A
I
N
D
K
S
G
T
L
A
S
Q
N
F
L
D
A
D
E
Q
K
R
N
A
Y
N
Q
A
V
S
A
A
E
T
I
L
N
------
T
A
K
T
A
V
E
Q
A
L
N
N
V
N
N
A
K
H
A
L
N
G
T
Q
N
L
N
N
A
K
Q
A
A
I
T
A
I
N
G
A
S
D
L
N
Q
K
Q
K
D
A
L
K
A
Q
A
N
G
A
Q
R
V
S
N
A
Q
D
V
Q
H
N
A
T
E
L
N
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_CBE
55.08
96%
496
- C5 -
4KJM
15
B:
[5-128]
-
G
N
L
Q
T
A
I
N
D
K
S
G
T
L
A
S
Q
N
F
L
D
A
D
E
Q
K
R
N
A
Y
N
Q
A
V
S
A
A
E
T
I
L
--------
A
K
T
A
V
E
Q
A
L
N
N
V
N
N
A
K
H
A
L
N
G
T
Q
N
L
N
N
A
K
Q
A
A
I
T
A
I
N
G
A
S
D
L
N
Q
K
Q
K
D
A
L
K
A
Q
A
N
G
A
Q
R
V
S
N
A
Q
D
V
Q
H
N
A
T
E
L
N
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
52.41
47%
218
- C5 -
2DGJ
2
EBHA_STAAM
A:
[2-248]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
M
G
Q
L
Q
H
G
I
D
D
E
N
A
T
K
Q
T
Q
K
Y
R
D
A
E
Q
S
K
K
T
A
Y
D
Q
A
V
A
A
A
K
A
I
L
N
K
Q
-----
D
K
A
A
V
D
R
A
L
Q
Q
V
T
S
T
K
D
A
L
N
G
D
A
K
L
A
E
A
K
A
A
A
R
Q
N
L
G
T
L
N
H
I
T
N
A
Q
R
T
A
L
E
G
Q
I
N
Q
A
T
T
V
D
G
V
N
T
V
K
T
N
A
N
T
L
D
G
A
M
N
S
L
Q
G
A
I
N
D
K
D
A
T
L
R
N
Q
N
Y
L
D
A
D
E
S
K
R
N
A
Y
T
Q
A
V
T
A
A
E
G
I
L
N
K
Q
T
G
G
N
T
S
K
A
D
V
D
N
A
L
N
A
V
T
R
A
K
A
A
L
N
G
A
E
N
L
R
N
A
K
T
S
A
T
N
T
I
N
G
L
P
N
L
T
Q
L
Q
K
D
N
L
K
H
Q
V
E
Q
A
Q
N
V
V
G
V
N
G
V
K
D
K
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
52.17
12%
67
* C4 *
4BUJ
3
SKI3_YEAST
B:
[3-1436]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
M
S
D
I
K
Q
L
L
K
E
A
K
Q
E
L
T
N
RD
Y
E
E
T
I
E
I
S
E
K
V
L
K
L
D
P
D
N
Y
F
A
H
I
F
L
-
G
K
A
L
S
S
L
P
A
S
N
N
V
S
S
N
R
N
L
E
----
R
A
T
N
H
Y
V
S
A
A
K
L
V
P
D
N
L
L
A
W
K
G
L
F
L
L
F
R
T
T
E
V
V
P
D
I
L
S
Y
D
E
Y
F
D
L
C
G
Q
Y
A
D
A
L
L
K
Q
E
Q
V
E
L
I
N
D
I
K
-----
L
L
K
K
T
H
P
D
C
Q
--
K
A
F
Y
Q
H
L
K
P
G
S
L
M
A
E
T
IG
R
T
P
Q
D
A
L
L
N
----
L
I
K
I
L
S
N
I
E
T
T
E
I
G
K
T
L
S
Q
N
R
L
K
L
K
-----
A
S
D
P
D
Y
Q
I
K
L
N
S
F
S
W
E
I
I
K
N
S
E
I
D
Q
L
Y
N
Q
L
V
N
I
L
A
D
--
D
Q
K
R
S
E
I
E
N
Q
W
L
E
Y
R
I
K
V
L
K
S
M
P
L
D
V
K
K
D
F
F
T
K
V
K
E
M
V
E
D
M
V
L
-
V
N
H
Q
S
L
L
A
W
Q
K
Y
F
E
W
T
D
Y
E
D
L
D
N
M
D
A
P
L
I
I
K
Y
F
K
K
F
P
K
D
P
L
A
M
I
L
Y
S
W
L
S
S
K
L
S
K
Y
D
I
K
S
L
E
S
D
D
I
E
I
G
L
L
E
E
E
V
V
T
V
L
T
E
N
I
V
K
C
K
N
N
I
L
A
H
R
I
L
C
Q
Y
Y
L
L
T
K
E
Y
E
A
A
L
P
Y
I
K
N
G
I
S
L
I
A
Y
N
I
K
D
L
-
G
V
H
L
P
L
T
K
R
E
F
S
L
D
L
A
T
V
Y
T
Y
V
D
A
P
K
D
H
N
A
A
L
K
L
Y
D
N
I
L
S
-------
G
D
F
S
N
I
Q
A
K
M
G
K
G
I
I
F
I
E
R
K
N
W
K
D
A
--
M
T
L
L
T
Q
V
H
E
Q
S
P
N
N
L
E
V
L
S
E
L
S
W
S
K
A
H
M
G
Y
M
D
E
A
L
A
G
L
D
T
V
I
K
G
I
------
K
G
M
D
L
R
S
I
D
F
R
A
L
----
N
L
W
R
Q
A
K
V
Y
I
M
K
H
A
S
A
K
Q
E
N
V
K
C
A
F
K
L
L
I
Q
S
I
K
I
L
D
T
-------------
F
A
P
G
F
S
T
L
G
D
I
Y
C
H
Y
YK
D
H
L
R
A
F
K
C
Y
F
K
A
F
D
L
D
A
G
D
Y
T
A
A
K
Y
I
T
E
T
Y
A
S
K
----
P
N
----
W
Q
A
A
S
S
I
A
S
R
L
I
K
G
-----------
E
K
A
K
A
E
L
R
S
N
N
W
P
F
R
V
V
--------
G
I
A
H
L
E
K
Q
E
E
S
D
S
I
E
W
F
Q
S
--
A
L
R
V
D
P
-------
N
D
V
E
S
W
V
G
L
G
Q
A
Y
H
A
C
G
R
-------
I
E
A
S
I
K
V
F
D
K
A
I
Q
L
R
P
S
H
T
F
A
Q
Y
F
K
A
I
S
L
C
D
V
G
E
Y
L
E
S
L
D
I
L
E
K
V
C
Q
E
A
A
T
E
---
E
S
F
Q
I
G
L
V
E
V
L
M
R
C
S
L
D
L
Y
S
Q
-
G
F
L
L
K
S
V
S
I
A
K
D
T
I
E
R
I
K
I
I
I
S
E
L
K
C
-------------
E
N
Q
Q
V
W
I
Y
L
S
Q
V
L
R
L
F
I
W
I
E
S
K
V
D
-
T
L
P
V
E
S
L
V
S
I
F
E
N
S
Q
F
S
G
S
E
E
I
D
S
V
D
N
I
K
I
D
T
L
L
D
S
T
T
D
D
N
V
S
I
A
C
K
F
L
I
L
A
S
K
Y
S
V
S
D
Q
K
F
T
D
I
A
G
T
V
R
A
S
Y
W
Y
N
I
G
I
S
E
L
T
A
F
I
T
L
K
E
P
Q
Y
R
D
A
A
I
F
A
F
K
K
S
I
Q
L
Q
S
N
T
S
E
T
W
I
G
L
G
I
A
T
MDIN
F
R
V
S
Q
H
C
F
I
K
A
T
A
L
E
P
K
A
T
N
T
W
F
N
L
A
M
L
G
L
K
K
K
D
T
E
F
A
Q
Q
V
L
N
K
L
Q
S
L
A
P
Q
D
S
S
P
W
L
G
M
A
L
I
L
E
E
Q
G
D
I
I
G
S
S
K
L
F
A
H
S
F
I
L
S
N
G
R
S
------------
K
A
A
Q
F
M
Y
A
K
N
V
L
E
N
H
I
N
N
G
D
D
E
R
D
I
E
T
V
E
K
L
T
T
A
S
I
A
L
E
Q
F
F
K
K
-------------
S
P
D
S
Q
F
A
L
Q
C
A
L
L
T
L
E
R
L
-----
H
H
Y
E
N
A
N
E
L
A
N
R
L
I
G
I
L
E
K
K
F
E
K
T
Q
D
E
R
E
L
F
N
F
A
I
I
K
G
Q
F
A
R
I
-
H
L
G
L
G
N
F
E
L
S
I
E
N
A
D
L
S
Q
G
I
I
S
E
S
S
D
E
K
S
M
K
T
K
I
S
N
H
I
C
L
G
L
S
Y
F
F
L
N
D
F
D
Q
T
L
N
Q
F
Q
E
L
L
S
I
S
K
--
D
S
K
H
L
V
V
L
I
A
K
V
L
Y
D
V
G
E
S
D
T
K
E
I
-
A
L
Q
E
L
T
E
Y
I
A
T
--------
S
G
A
D
L
L
V
T
L
T
I
A
A
M
S
I
L
D
D
K
--------
R
E
D
L
S
I
I
--
L
E
E
L
K
A
L
P
L
S
K
Q
I
I
D
K
H
K
D
A
P
Y
L
I
E
E
I
T
K
R
L
Y
R
N
D
T
G
K
Q
V
W
Q
R
S
A
Y
F
F
P
N
N
L
K
V
W
E
R
L
D
K
N
I
Q
R
R
I
A
S
N
G
Q
N
K
V
T
A
E
E
M
S
--
K
L
Y
C
E
-
S
K
N
L
R
S
I
Q
R
G
M
F
L
C
P
W
N
V
T
A
V
K
A
L
N
E
C
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
49.06
23%
281
- C5 -
4KDE
-
MDH_THETH
A:
[111-331]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
G
-----
R
A
L
A
E
V
A
K
---
K
D
V
-------------------
K
V
L
-----------
V
V
G
N
P
A
N
T
N
A
L
I
A
Y
K
N
A
---------
P
G
L
N
P
-
R
N
F
T
A
--
M
T
R
L
D
H
N
R
A
K
A
-----------
Q
L
A
K
K
T
G
T
G
V
D
R
I
R
R
M
T
V
W
G
NHSST
M
F
P
D
LFHA
E
V
D
G
R
P
A
L
E
L
V
D
M
E
W
Y
E
K
V
F
I
-----
P
T
V
A
Q
R
G
A
A
I
I
Q
A
RGAS
S
-----
A
A
S
A
A
N
A
A
I
E
H
I
R
D
W
A
L
G
T
P
E
G
D
W
V
S
M
A
V
P
S
Q
G
E
Y
G
I
P
-------
E
G
--
I
V
Y
S
F
P
V
T
A
K
D
G
A
Y
R
V
V
E
GLEIN
E
F
A
R
K
R
M
E
I
T
A
Q
E
L
L
D
E
M
E
Q
V
K
A
L
G
L
I
R
K
L
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
47.34
16%
103
- C4 -
5CA8
2
?
A:
[27-687]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
I
Q
I
I
D
E
N
K
H
F
N
T
G
I
L
D
Y
I
N
K
T
S
P
A
D
V
G
N
N
----
Y
H
I
I
S
V
F
G
S
Q
S
T
G
K
S
T
-
L
L
N
R
L
F
N
T
N
F
D
V
M
G
I
W
L
A
Y
S
P
V
----
V
S
T
T
L
G
H
T
T
S
K
S
N
I
L
V
M
D
V
E
G
T
D
E
D
Q
D
F
E
R
K
A
A
L
F
A
L
S
T
S
E
--
V
L
I
I
N
I
W
E
T
Q
V
G
L
Y
Q
G
A
N
M
G
L
L
K
-
T
V
F
E
V
N
L
-
S
L
F
G
K
S
K
L
E
T
-------
H
N
D
H
K
V
L
L
L
I
V
I
R
D
H
V
--
G
V
T
P
V
E
S
L
A
K
T
F
T
L
D
L
Q
N
M
W
S
S
L
A
K
P
A
E
L
E
H
L
Q
--
F
A
D
F
F
D
V
T
F
H
A
L
N
H
K
V
L
Q
P
K
E
F
G
E
G
I
N
R
L
G
D
R
L
V
V
S
N
E
L
F
K
P
E
Y
H
H
D
V
P
I
D
G
W
T
M
Y
A
E
R
C
W
E
Q
I
E
T
N
KDL
D
L
P
T
Q
Q
I
L
V
A
Q
F
K
C
D
E
---
I
V
E
S
V
F
Q
-
E
F
L
T
K
Y
Q
H
H
F
-
K
E
V
D
A
A
P
D
F
---
E
E
L
G
A
L
F
A
D
L
R
Q
D
A
F
E
D
Y
D
A
S
A
S
R
Y
-------
N
K
A
V
Y
E
Q
K
R
K
K
L
R
W
-------------
L
I
N
D
K
L
K
E
V
F
D
V
H
A
-
K
N
L
C
---------
N
T
L
L
E
K
F
E
K
D
L
V
A
L
K
G
--
K
D
F
A
-----
V
-
N
V
K
T
L
S
T
K
L
V
E
D
V
N
F
Q
V
-----
S
L
M
S
L
Q
G
D
L
S
L
D
E
-
I
I
L
A
L
T
K
D
I
D
A
I
---
V
A
K
Q
Q
V
V
E
L
N
---
S
I
---
V
N
------
K
S
V
K
K
L
S
A
S
L
S
K
S
I
Q
F
E
L
G
--
D
P
N
E
E
T
W
D
N
V
------
L
Q
Q
------
F
K
G
V
Y
E
K
F
G
G
D
F
G
L
G
T
S
-
S
T
Q
N
-
Q
Q
A
I
E
K
F
K
F
K
S
W
C
Q
F
Y
D
V
T
H
K
--
L
I
S
R
E
K
L
-----
L
A
L
L
Q
D
R
F
---
D
D
K
FRYDENG
L
P
K
L
Y
LN
E
Q
D
L
E
K
T
F
-----------
A
V
A
K
Q
H
A
L
Q
V
L
P
I
L
T
F
A
K
L
A
D
G
S
E
I
V
P
D
Y
D
I
F
D
S
K
L
R
--
E
Q
F
L
D
H
C
F
A
E
I
I
T
E
Q
E
K
L
E
V
L
A
K
F
K
K
E
V
D
A
K
Y
I
E
T
K
R
S
I
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
47.11
24%
574
- C5 -
4TKO
-
?
B:
[72-242]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
K
K
A
L
E
I
-------------
K
I
Q
K
L
E
K
G
L
H
I
S
L
S
A
K
K
L
K
---------
V
E
S
L
K
K
K
R
E
A
L
R
E
K
L
L
Q
V
E
E
K
I
-----
K
L
V
K
L
D
W
E
R
Y
K
S
L
F
Q
K
G
L
I
PRRKF
E
E
V
D
T
N
L
K
V
L
-
L
H
-
E
R
E
Y
L
E
K
S
I
Q
E
I
NTE
I
K
R
A
K
K
G
I
E
N
---
A
R
---
N
E
F-----
K
T
I
E
E
L
K
K
E
L
S
S
L
E
E
E
I
K
S
L
K
E
R
I
K
T
A
E
Q
K
I
------
K
D
T
------
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
46.30
12%
271
- C5 -
3I9Y
-
?
A:
[50-317]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
M
I
E
A
R
Q
V
S
E
L
S
T
R
I
I
S
S
V
Q
M
L
S
N
A
Q
N
E
Q
E
R
K
E
A
G
R
V
L
F
E
Q
L
E
-------------
S
L
L
T
H
I
K
E
L
G
G
E
S
F
-
D
S
K
L
---------
L
D
A
L
E
S
N
V
Q
N
V
I
N
N
L
A
E
L
G
V
T
V
-----
E
-
R
K
L
W
L
A
K
E
I
D
T
R
V
E
E
M
R
-----
L
L
S
E
E
L
E
Q
L
T
-
R
T
L
D
L
T
E
R
L
H
E
L
H
L
L
---
A
F
K
M
L
N
Q
I
E
E
---
A
R
T
LT
N
V
------
D
R
I
Q
Q
I
Q
T
A
F
E
N
N
L
K
I
M
K
R
R
V
L
A
V
E
D
--
P
T
R
------
S
K
Q
------
M
S
Q
L
L
T
E
L
G
K
R
Q
V
V
F
T
I
-
L
L
Q
Q
Y
E
N
N
E
Q
S
Q
Q
L
M
Q
K
T
L
E
L
F
S
E
L
N
--
S
-
T
V
N
K
L
-----
V
D
D
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
46.21
16%
757
* C5 *
4K12
-
?
B:
[3-84]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
S
E
R
D
K
A
R
K
E
V
E
E
Y
V
K
K
I
V
G
E
S
Y
A
K
S
T
K
K
R
H
T
I
T
V
A
L
V
N
E
L
N
N
I
K
N
E
Y
L
N
K
I
V
E
S
T
S
E
S
E
L
Q
I
L
M
M
E
S
R
S
K
V
D
E
A
V
S
K
F
E
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
42.61
23%
282
- C5 -
4KDF
3
MDH_THETH
A:
[111-326]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
G
-----
R
A
L
A
E
V
A
K
---
K
D
V
-------------------
K
V
L
-----------
V
V
G
N
P
A
N
T
N
A
L
I
A
Y
K
N
A
---------
P
G
L
N
P
-
R
N
F
T
A
--
M
T
R
L
D
H
N
R
A
K
A
-----------
Q
L
A
K
K
T
G
T
G
V
D
R
I
R
R
M
T
V
W
G
NHSST
M
F
P
D
LFHA
E
V
D
G
R
P
A
L
E
L
V
D
M
E
W
Y
E
K
V
F
I
-----
P
T
V
A
Q
R
G
A
A
I
I
Q
A
RGAS
S
-----
A
A
S
A
A
N
A
A
I
E
H
I
R
D
W
A
L
G
T
P
E
G
D
W
V
S
M
A
V
P
S
Q
G
E
Y
G
I
P
-------
E
G
--
I
V
Y
S
F
P
V
T
A
K
D
G
A
Y
R
V
V
E
GLEIN
E
F
A
R
K
R
M
E
I
T
A
Q
E
L
L
D
E
M
E
Q
V
K
A
L
G
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
42.49
14%
383
- C5 -
4U5A
-
?
A:
[8-200]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
N
I
I
E
E
F
D
K
L
S
D
D
F
S
N
D
I
N
A
T
K
-----
Q
-
T
I
K
D
L
F
L
D
I
E
A
S
-
D
D
V
V
-----
K
L
L
S
K
Y
S
F
V
P
-
E
E
-
K
L
N
I
I
D
G
I
L
R
S
F
---
I
E
N
N
K
T
H
V
I
N
SS
N
A
Y
---
I
Y
------
I
Q
K
E
K
I
K
N
V
C
N
F
I
L
K
K
L
N
S
L
I
Q
I
N
E
L
N
K
S
H
I
I
L
K
YGK
G
E
A
------
K
K
G
V
L
E
S
I
K
N
N
D
D
I
S
K
N
-
L
K
S
E
L
L
K
Y
R
V
S
E
L
I
N
F
I
T
P
I
Y
D
D
F
-
I
--
K
-
N
L
T
D
L
-----
I
N
D
L
Q
I
K
L
---
K
N
I
-------------------
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
41.79
12%
167
- C2 -
1W3B
-
OGT1_HUMAN
B:
[1-388]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
M
E
L
A
H
R
E
Y
Q
A
G
D
F
E
A
A
E
R
H
C
M
Q
L
W
R
Q
E
P
---
D
N
T
G
V
L
L
L
L
S
S
I
H
F
Q
CRRL
D
R
S
A
H
F
S
T
L
A
I
K
Q
N
P
L
L
A
E
A
Y
S
N
L
G
N
V
Y
K
E
R
G
Q
L
Q
E
A
-------------
I
---
E
H
Y
R
H
A
L
R
L
K
P
--
D
F
I
D
G
Y
I
N
L
A
A
A
L
V
A
A
G
D
M
E
G
A
V
Q
A
Y
V
S
A
L
Q
Y
N
----
P
D
L
Y
C
V
R
S
D
L
G
N
L
L
K
A
L
-----------
G
R
L
E
E
A
K
A
C
Y
L
K
A
I
E
T
Q
P
N
F
--------
A
V
A
W
S
N
L
G
C
V
F
N
A
Q
G
E
I
W
L
--
A
I
H
H
F
E
K
A
V
T
L
D
P
N
F
L
D
A
Y
I
N
L
G
N
V
L
K
E
A
R
I
-------
F
D
R
A
V
A
A
Y
L
R
A
L
S
L
S
P
N
H
A
V
V
H
G
N
L
A
C
V
Y
Y
E
Q
G
L
I
D
L
A
I
D
T
Y
R
R
A
I
E
L
Q
P
H
F
----------
P
D
A
Y
C
N
L
A
N
A
L
K
E
K
-
G
S
V
A
E
A
E
D
C
Y
N
T
A
L
R
L
C
P
T
H
A
D
S
Y
R
K
A
L
E
V
F
P
E
F
A
A
A
H
S
N
L
A
S
V
L
Q
Q
Q
G
K
L
Q
E
A
L
M
H
Y
K
E
A
I
R
I
S
P
T
F
A
D
A
Y
S
N
M
G
N
T
L
K
E
M
Q
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
41.38
9%
212
- C4 -
3AY5
-
CCDB1_HUMAN
A:
[14-360]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
S
P
L
E
Q
L
R
H
L
A
E
E
L
R
L
L
L
P
-
R
V
R
V
G
E
A
T
E
E
F
N
R
E
M
F
W
R
-------------
R
L
N
E
A
A
V
T
V
S
R
E
A
T
-
T
L
T
I
V
F
SQLPLPS
P
Q
E
T
Q
K
F
C
E
Q
V
H
A
A
I
K
A
F
I
A
V
Y
Y
L
LPK
D
-
Q
G
I
T
L
R
K
L
V
R
G
A
T
L
D
I
V
-----
D
G
M
A
Q
L
M
E
V
L
-
S
V
-
N
--
S
V
W
V
A
C
Q
Q
M
---
P
Q
I
P
R
D
--
N
K
---
A
A
---
A
L
------
L
M
L
T
K
N
V
D
F
V
K
D
A
H
E
E
M
E
Q
A
V
E
E
S
D
P
Q
D
L
Y
W
------
S
E
D
------
D
Q
E
L
I
I
P
C
L
A
L
V
R
A
S
K
A
-
C
L
K
K
I
R
M
L
V
A
E
N
G
K
K
D
Q
V
A
Q
L
D
D
I
V
D
I
S
D
-
E
I
S
P
S
-----
V
D
D
L
A
L
S
I
YPP
M
S
H
-------------------
L
T
V
-----------
R
I
N
S
A
K
L
V
S
V
L
K
K
A
L
E
I
T
-
K
A
-
S
H
V
T
P
S
W
I
P
L
L
I
N
A
I
--
D
H
C
M
N
R
I
K
E
L
T
Q
S
E
L
E
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
40.46
29%
465
- C5 -
1U4G
4
ELAS_PSEAE
A:
[162-293]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
E
A
F
S
D
M
A
G
E
A
A
E
F
Y
M
R
G
K
N
D
F
L
I
G
Y
D
IKKGSG
A
L
R
Y
M
D
Q
P
S
R
D
G
-
R
S
I
D
N
A
S
Q
Y
Y
N
G
I
D
V
--
H
H
S
S
G
V
Y
N
R
A
F
Y
L
L
A
N
S
P
G
W
D
T
R
K
A
F
E
V
F
V
D
A
N
R
Y
Y
W
T
A
T
S
N
Y
N
S
G
A
C
G
V
I
R
S
A
Q
N
R
N
Y
S
A
A
D
V
T
R
A
F
S
T
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
40.17
29%
466
- C5 -
3DBK
4
ELAS_PSEAE
A:
[162-293]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
E
A
F
S
D
M
A
G
E
A
A
E
F
Y
M
R
G
K
N
D
F
L
I
G
Y
D
IKKGSG
A
L
R
Y
M
D
Q
P
S
R
D
G
-
R
S
I
D
N
A
S
Q
Y
Y
N
G
I
D
V
--
H
H
S
S
G
V
Y
N
R
A
F
Y
L
L
A
N
S
P
G
W
D
T
R
K
A
F
E
V
F
V
D
A
N
R
Y
Y
W
T
A
T
S
N
Y
N
S
G
A
C
G
V
I
R
S
A
Q
N
R
N
Y
S
A
A
D
V
T
R
A
F
S
T
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
39.82
29%
466
- C5 -
4K89
8
?
A:
[162-293]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
E
A
F
S
D
M
A
G
E
A
A
E
F
Y
M
R
G
K
N
D
F
L
I
G
Y
D
IKKGSG
A
L
R
Y
M
D
Q
P
S
R
D
G
-
R
S
I
D
N
A
S
Q
Y
Y
N
G
I
D
V
--
H
H
S
S
G
V
Y
N
R
A
F
Y
L
L
A
N
S
P
G
W
D
T
R
K
A
F
E
V
F
V
D
A
N
R
Y
Y
W
T
A
T
S
N
Y
N
S
G
A
C
G
V
I
R
S
A
Q
N
R
N
Y
S
A
A
D
V
T
R
A
F
S
T
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
39.78
29%
473
- C5 -
1EZM
2
ELAS_PSEAE
A:
[162-293]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
E
A
F
S
D
M
A
G
E
A
A
E
F
Y
M
R
G
K
N
D
F
L
I
G
Y
D
IKKGSG
A
L
R
Y
M
D
Q
P
S
R
D
G
-
R
S
I
D
N
A
S
Q
Y
Y
N
G
I
D
V
--
H
H
S
S
G
V
Y
N
R
A
F
Y
L
L
A
N
S
P
G
W
D
T
R
K
A
F
E
V
F
V
D
A
N
R
Y
Y
W
T
A
T
S
N
Y
N
S
G
A
C
G
V
I
R
S
A
Q
N
R
N
Y
S
A
A
D
V
T
R
A
F
S
T
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------