@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1290: (2016-03-24 )
MDKSLFEQARPILEQIQDNGFEAYYVGGSVRDYVMGRNIHDIDITTSATPDEIESIFSHTIPVGKEHGTINVVFNDENYEVTTFRAEEDYVDHRRPSGVTFVRDLYEDLQRRDFTMNAIAMDTAYKLYDYFDGQQDINNRIIRTVGIAEERFQEDALRMIRCLRFQSQLSFDIAMETFEAMRTQMADIKFLSIERIVIELTKLMRGINVEESFNHLKSLKAFNYMPYFEQLDMNQINVTEPIDLELLIAIVSVKFDINYSLKPLKLSNRQVKDINQYIQIMNALPSIITKEQLKMFVYDYDTNLIKNVMVAADVLKANDIQGHEPLIVNLQTIDETLHRLPMHNRKDMMVNGGVLMAHLNAKSGPWLKDVLRQIEIAIVTGKVSNEETEILKWVDNHVKI
Atome Classification :
(31 SA)
------------......-...10........20---.........30........---40........50......-.-------.60----.----..----....-------.--.70...-.----....80........90........100.--.-----.....110.......120-.-.---------..----...130.......140.......150.......160.......---170--........180...--.--...190.......200.......210.......-220.....--------..230....-------.-------..---------------------------240..-------......------.250-----.....---------------------..260-.........270.......280.-.-----...-------.-------.290.......300.......310.....-..320.......330.....----..340.....-..350.......360.......370.......380.......390.......400
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------M
D
K
S
L
F
-
E
Q
A
R
P
I
L
E
Q
I
Q
DNG----
F
E
A
Y
Y
VGG
S
V
R
D
Y
V
MGR
N
I
---
H
D
I
D
ITTSA
T
P
D
E
I
E
S
I
F
-
S
-------HT-----I----PV----GKEH-------
G
--
T
I
N
V
V
F-N----DEN
Y
E
V
T
T
F
RAEEDYVDHRRPSG
V
T
F
V
R
--
D
-----
L
Y
E
D
L
Q
RRDFTM
N
A
I
A
M
D
-
T
-
A
---------
Y
K
----
L
Y
D
YFDGQ
Q
D
I
NN
R
I
I
R
TVG
I
A
E
E
R
F
Q
E
D
A
L
R
M
I
R
C
L
R
F
Q
S
QL---
S
F
---
D
I
A
M
E
T
F
E
A
M
R
T
Q
M--A--D
I
K
F
L
S
I
E
R
I
V
I
E
L
T
K
L
M
RGI
N
V
E
E
S
F
N
H
L
K
S
L
-
K
AFNYMP
Y
--------
F
E
QLDMNQI-------N-------VT---------------------------E--P
I
-------
D
L
E
L
L
I
------
A
I
V
S
-----
V
K
F
D
I
---------------------NYS---LK
P
L
KLSNR
Q
V
K
D
I
N
Q
Y
I
Q
I
M
N
A
-
L
-----
P
S
I
-------
I
-------
T
K
E
Q
L
K
M
F
V
Y
DYD
T
N
L
I
K
N
V
M
V
A
A
D
V
L
KA-NDIQGHE
P
L
I
V
N
L
Q
T
I
D
E
T
L
----
H
RLPMHNRK
D
-
M
M
VNG
G
V
L
M
A
H
LNAKSG
P
W
L
K
D
V
L
R
QI
E
I
A
I
V
T
GKVSN
E
E
T
E
I
L
K
W
V
D
N
HVKI--
3
PsiBlast_PDB
95.71
36%
-103
- C3 -
1MIW
2
CCA_GEOSE
A:
[2-393]
--------------
K
P
P
F
-
Q
E
A
L
G
I
I
Q
Q
L
K
Q
H
G
----
Y
D
A
Y
F
V
G
G
A
V
R
D
L
L
L
G
R
P
I
---
G
D
V
D
I
A
T
S
A
L
P
E
D
V
M
A
I
F
-
P
-------
K
T
-----
I
----
D
V
----
G
S
K
H
-------
G
--
T
V
V
V
V
H
-
K
----
G
K
A
Y
E
V
T
T
F
K
T
D
G
---------
S
V
T
F
V
R
--
S
-----
L
E
E
D
L
K
R
R
D
F
T
M
N
A
I
A
M
D
-
E
-
Y
---------
G
T
----
I
I
D
P
F
G
G
R
E
A
I
R
R
R
I
I
R
T
V
G
E
A
E
K
R
F
R
E
D
A
L
R
M
M
R
A
V
R
F
V
S
E
L
---
G
F
---
A
L
A
P
D
T
E
Q
A
I
V
Q
N
A
--
P
--
L
L
A
H
I
S
V
E
R
M
T
M
E
M
E
K
L
L
G
G
P
F
A
A
R
A
L
P
L
L
A
E
T
-
G
L
N
A
Y
L
P
G
--------
L
A
G
K
E
-
K
Q
L
-------
R
-------
L
A
---------------------------
A
--
A
Y
-------
R
W
P
W
L
A
A
R
E
E
R
W
A
L
L
C
-----
H
A
L
G
V
---------------------
Q
E
S
R
P
F
L
R
A
W
K
L
P
N
K
V
V
D
E
A
G
---
A
I
L
T
A
-
L
A
D
I
PR
P
E
A
-------
W
-------
T
N
E
Q
L
--
F
S
A
G
L
E
R
A
L
S
V
E
T
V
R
A
A
-
F
T
G
A
-
P
P
G
P
W
H
E
K
L
R
R
R
F
A
S
-----------
L
P
I
K
T
K
G
E
-
L
A
V
N
G
K
D
V
I
E
W
V
G
K
P
A
G
P
W
V
K
E
A
L
D
A
I
W
R
A
V
V
N
G
E
V
E
N
E
K
E
R
I
Y
A
W
L
--------
2
PsiBlast_PDB
95.51
36%
-104
- C3 -
1MIV
1
CCA_GEOSE
A:
[2-393]
--------------
K
P
P
F
-
Q
E
A
L
G
I
I
Q
Q
L
K
Q
H
G
----
Y
D
A
Y
F
V
G
G
A
V
R
D
L
L
L
G
R
P
I
---
G
D
V
D
I
A
T
S
A
L
P
E
D
V
M
A
I
F
-
P
-------
K
T
-----
I
----
D
V
----
G
S
K
H
-------
G
--
T
V
V
V
V
H
-
K
----
G
K
A
Y
E
V
T
T
F
K
T
D
G
---------
S
V
T
F
V
R
--
S
-----
L
E
E
D
L
K
R
R
D
F
T
M
N
A
I
A
M
D
-
E
-
Y
---------
G
T
----
I
I
D
P
F
G
G
R
E
A
I
R
R
R
I
I
R
T
V
G
E
A
E
K
R
F
R
E
D
A
L
R
M
M
R
A
V
R
F
V
S
E
L
---
G
F
---
A
L
A
P
D
T
E
Q
A
I
V
Q
N
A
--
P
--
L
L
A
H
I
S
V
E
R
M
T
M
E
M
E
K
L
L
G
G
P
F
A
A
R
A
L
P
L
L
A
E
T
-
G
L
N
A
Y
L
P
G
--------
L
A
G
K
E
-
K
Q
L
-------
R
-------
L
A
---------------------------
A
--
A
Y
-------
R
W
P
W
L
A
A
R
E
E
R
W
A
L
L
C
-----
H
A
L
G
V
---------------------
Q
E
S
R
P
F
L
R
A
W
K
L
P
N
K
V
V
D
E
A
G
---
A
I
L
T
A
-
L
A
D
I
PR
P
E
A
-------
W
-------
T
N
E
Q
L
--
F
S
A
G
L
E
R
A
L
S
V
E
T
V
R
A
A
-
F
T
G
A
-
P
P
G
P
W
H
E
K
L
R
R
R
F
A
S
-----------
L
P
I
K
T
K
G
E
-
L
A
V
N
G
K
D
V
I
E
W
V
G
K
P
A
G
P
W
V
K
E
A
L
D
A
I
W
R
A
V
V
N
G
E
V
E
N
E
K
E
R
I
Y
A
W
L
--------
29
HHSearch
95.42
35%
-97
- C3 -
1MIW
2
CCA_GEOSE
A:
[1-398]
-------------
M
K
P
P
F
-
Q
E
A
L
G
I
I
Q
Q
L
K
Q
H
G
----
Y
D
A
Y
F
V
G
G
A
V
R
D
L
L
L
G
R
P
I
---
G
D
V
D
I
A
T
S
A
L
P
E
D
V
M
A
I
F
-
P
-------
K
T
-----
I
----
D
V
----
G
S
K
H
-------
G
--
T
V
V
V
V
H
-
K
----
G
K
A
Y
E
V
T
T
F
K
T
D
G
---------
S
V
T
F
V
R
--
S
-----
L
E
E
D
L
K
R
R
D
F
T
M
N
A
I
A
M
D
-
E
-
Y
---------
G
T
----
I
I
D
P
F
G
G
R
E
A
I
R
R
R
I
I
R
T
V
G
E
A
E
K
R
F
R
E
D
A
L
R
M
M
R
A
V
R
F
V
S
E
L
---
G
F
---
A
L
A
P
D
T
E
Q
A
I
V
Q
N
A
--
P
--
L
L
A
H
I
S
V
E
R
M
T
M
E
M
E
K
L
L
G
G
P
F
A
A
R
A
L
P
L
L
A
E
T
-
G
L
N
A
-
Y
L
P
--------
G
L
A
G
K
E
K
Q
L
R
L
A----
A
-------
A
Y
RW-------------------------
P
WL
A
A
-------
R
E
E
R
W
A
------
L
L
-
C
-----
H
A
L
G
V
QE
S
------------------
R
P
F
---
L
R
A
W
K
L
P
N
K
V
V
D
E
A
G
A
I
L
T
A
L
A
D
-
I
-----
P
R
----------------
P
E
A
W
T
N
E
Q
L
F
S
A
G
L
E
R
A
L
S
V
E
T
V
R
-
A
A
F
T
-
G
-----
A
P
P
G
P
W
H
E
K
L
R
R
R
F
----
A
S
L
P
I
K
T
K
G
E
-
L
A
V
N
G
K
D
V
I
E
W
V
G
K
P
A
G
P
W
V
K
E
A
L
D
A
I
W
R
A
V
V
N
G
E
V
E
N
E
K
E
R
I
Y
A
W
L
M
E
R
N
R
---
1
PsiBlast_PDB
95.37
37%
-104
- C3 -
1MIY
3
CCA_GEOSE
A:
[2-393]
--------------
K
P
P
F
-
Q
E
A
L
G
I
I
Q
Q
L
K
Q
H
G
----
Y
D
A
Y
F
V
G
G
A
V
R
D
L
L
L
G
R
P
I
---
G
D
V
D
I
A
T
S
A
L
P
E
D
V
M
A
I
F
-
P
-------
K
T
-----
I
----
D
V
----
G
S
K
H
-------
G
--
T
V
V
V
V
H
-
K
----
G
K
A
Y
E
V
T
T
F
K
T
D
G
---------
S
V
T
F
V
R
--
S
-----
L
E
E
D
L
K
R
R
D
F
T
M
N
A
I
A
M
D
-
E
-
Y
---------
G
T
----
I
I
D
P
F
G
G
R
E
A
I
R
R
R
I
I
R
T
V
G
E
A
E
K
R
F
R
E
D
A
L
R
M
M
R
A
V
R
F
V
S
E
L
---
G
F
---
A
L
A
P
D
T
E
Q
A
I
V
Q
N
A
--
P
--
L
L
A
H
I
S
V
E
R
M
T
M
E
M
E
K
L
L
G
G
P
F
A
A
R
A
L
P
L
L
A
E
T
-
G
L
N
A
Y
L
P
G
--------
L
A
G
K
E
-
K
Q
L
-------
R
-------
L
A
---------------------------
A
--
A
Y
-------
R
W
P
W
L
A
A
R
E
E
R
W
A
L
L
C
-----
H
A
L
G
V
---------------------
Q
E
S
R
P
F
L
R
A
W
K
L
P
N
K
V
V
D
E
A
G
---
A
I
L
T
A
-
L
A
D
I
PR
P
E
A
-------
W
-------
T
N
E
Q
L
--
F
S
A
G
L
E
R
A
L
S
V
E
T
V
R
A
A
-
F
T
G
A
-
P
P
G
P
W
H
E
K
L
R
R
R
F
A
S
-----------
L
P
I
K
T
K
G
E
-
L
A
V
N
G
K
D
V
I
E
W
V
G
K
P
A
G
P
W
V
K
E
A
L
D
A
I
W
R
A
V
V
N
G
E
V
E
N
E
K
E
R
I
Y
A
W
L
--------
21
PsiBlast_CBE
94.64
37%
-102
- C3 -
1MIY
3
CCA_GEOSE
B:
[2-393]
--------------
K
P
P
F
-
Q
E
A
L
G
I
I
Q
Q
L
K
Q
H
G
----
Y
D
A
Y
F
V
G
G
A
V
R
D
L
L
L
G
R
P
I
---
G
D
V
D
I
A
T
S
A
L
P
E
D
V
M
A
I
F
-
P
-------
K
T
-----
I
----
D
V
----
G
S
K
H
-------
G
--
T
V
V
V
V
H
-
K
----
G
K
A
Y
E
V
T
T
F
K
T
D
G
---------
S
V
T
F
V
R
--
S
-----
L
E
E
D
L
K
R
R
D
F
T
M
N
A
I
A
M
D
-
E
-
Y
---------
G
T
----
I
I
D
P
F
G
G
R
E
A
I
R
R
R
I
I
R
T
V
G
E
A
E
K
R
F
R
E
D
A
L
R
M
M
R
A
V
R
F
V
S
E
L
---
G
F
---
A
L
A
P
D
T
E
Q
A
I
V
Q
N
A
--
P
--
L
L
A
H
I
S
V
E
R
M
T
M
E
M
E
K
L
L
G
G
P
F
A
A
R
A
L
P
L
L
A
E
T
-
G
L
N
A
Y
L
P
G
--------
L
A
G
K
E
-
K
Q
L
-------
R
-------
L
A
---------------------------
A
--
A
Y
-------
R
W
P
W
L
A
AREERW
A
L
L
C
-----
H
A
L
G
V
---------------------
Q
E
S
RPF
L
R
A
W
K
L
P
N
K
V
V
D
E
A
G
---
A
I
L
T
A
-
L
ADIPR
P
E
A
-------
W
-------
T
N
E
Q
L
--
F
S
A
G
L
E
R
A
L
S
V
E
T
V
R
A
A
-
F
T
G
A
-
P
P
G
P
W
H
E
K
L
R
R
R
F
A
S
-----------
L
P
I
K
T
K
G
E
-
L
A
V
N
G
K
D
V
I
E
W
V
G
K
P
A
G
P
W
V
K
E
A
L
D
A
I
W
R
A
V
V
N
G
E
V
E
N
E
K
E
R
I
Y
A
W
L
--------
54
Fugue
74.34
23%
-68
- C3 -
3AQL
2
?
A:
[1-411]
QVTVIPREQHAI
S
R
K
D
I
S
-
E
N
A
L
K
V
M
Y
R
L
N
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
P
---
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
-
R
-------
N
C
-----
R
----
L
V
----
G
R
R
F
-------
R
--
L
A
H
V
M
F
-
G
----
P
E
I
I
E
V
A
T
F
R
G
N
I
F
-------------
G
--
S
-----
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
V
A
-
D
---------
F
T
----
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
---
G
M
---
R
I
S
P
E
T
A
E
P
I
P
R
L
A
--
T
--
L
L
N
D
I
P
P
A
H
L
F
E
E
S
L
K
L
L
Q
A
G
Y
G
Y
E
T
Y
K
L
L
C
E
Y
-
H
L
F
Q
P
L
----------
F
P
T
I
T
-
R
Y
F
-------
T
-------
E
N
---------------------------
G
--
D
S
-------
P
M
E
R
I
I
------
E
Q
V
L
-----
K
N
T
D
T
---------------------
R
I
H
----------
N
D
M
R
V
N
P
A
F
L
F
A
A
M
F
W
-
Y
-----
P
L
L
-------
E
-------
T
A
Q
K
I
A
Q
E
S
G
L
T
Y
H
D
A
F
A
L
A
M
N
D
V
L
D
E
A
C
-
R
S
L
A
I
P
K
R
L
T
T
L
T
R
D
I
W
Q
L
Q
----
L
R
M
S
R
R
Q
G
K
-----
R
A
W
K
L
L
E
H
P
K
F
R
A
A
Y
D
L
L
A
L
R
A
E
V
E
R
N
A
E
L
Q
R
L
V
K
W
W
G
E
F
Q
V
S
A
P
P
D
Q
K
G
M
L
32
HHSearch
73.82
26%
-90
- C3 -
3AQL
2
?
A:
[15-352]
--------------
K
D
I
S
-
E
N
A
L
K
V
M
Y
R
L
N
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
P
---
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
-
R
-------
N
C
-----
R
----
L
V
----
G
R
R
F
-------
R
--
L
A
H
V
M
F
-
G
----
P
E
I
I
E
V
A
T
F
R
G
-------------
N
I
F
G
--
S
-----
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
-
V
A
D
---------
F
T
----
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
---
G
M
---
R
I
S
P
E
T
A
E
P
I
P
R
L
A
--
T
--
L
L
N
D
I
P
P
A
H
L
F
E
E
S
L
K
L
L
Q
A
G
Y
G
Y
E
T
Y
K
L
L
C
E
Y
-
H
L
F
Q
P
L
F
P
--------
T
I
T
R
Y
F
T
E
N
GDS
P
M
E
R
I
I
E
Q
V
L
K
N
T
D
T
R
I
H
N
DM--------------------
R
--
V
N
-------
P
A
F
L
F
A
------
A
M
-
F
W
Y
P
L
L
E
T
A
Q
K
I
A
Q
E
S
GLT
Y
H
D
A
F
A
L
A
M
N
D
V
L
D
E
A
---
C
R
S
L
A
I
P
K
R
L
T
T
L
T
R
D
I
W
Q
L
Q
L
R
-------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
71.71
33%
-94
- C3 -
4X4W
10
TRNT1_HUMAN
B:
[12-284]
--------------
Q
S
L
F
T
E
G
L
K
S
L
T
E
L
F
V
K
E
N
----
H
E
L
R
I
A
G
G
A
V
R
D
L
L
N
G
V
K
P
---
Q
D
I
D
F
A
T
T
A
T
P
T
Q
M
K
E
M
F
Q
S
-------
A
G
-----
I
----
R
M
I
N-------------
G
--
T
I
T
A
R
L
-
H
----
E
E
N
F
E
I
T
T
L
R
I
--
D
V
T
T
D
---
A
E
V
E
F
T
T
--
D
-----
W
Q
K
D
A
E
R
R
D
L
T
I
N
S
M
F
L
G
-
F
-
D
---------
G
T
----
L
F
D
Y
F
N
G
Y
E
D
L
K
N
K
K
V
R
F
V
G
H
A
K
Q
R
I
Q
E
D
Y
L
R
I
L
R
Y
F
R
F
Y
G
R
I
VDK
P
G
---
D
H
D
P
E
T
L
E
A
I
A
E
N
A
--
K
--
G
L
A
G
I
S
G
E
R
I
W
V
E
L
K
K
I
L
V
G
N
H
V
----
N
H
L
I
H
L
I
Y
D
L
D
V
A
P
Y
IGLPANAS
L
E
E
F
D
K
V
S
K
-------
N
-------
V
D
GF-------------------------
S
--
P
K
-------
P
V
T
L
L
A
------
S
L
F
K
-----
V
Q
D
D
V
---------------------
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
70.94
31%
-90
- C3 -
3AQM
1
?
B:
[15-249]
--------------
K
D
I
S
-
E
N
A
L
K
V
M
Y
R
L
N
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
P
---
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
-
R
-------
N
C
-----
R
----
L
V
----
G
R
R
F
-------
R
--
L
A
H
V
M
F
-
G
----
P
E
I
I
E
V
A
T
F
R
G
--------------------NIFGS
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
-
V
-
A
D--------
F
T
----
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
---
G
M
---
R
I
S
P
E
T
A
E
P
I
P
R
L
A
--
T
--
L
L
N
D
I
P
P
A
R
L
F
E
E
S
L
K
L
L
Q
A
G
Y
G
Y
E
T
Y
K
L
L
C
E
Y
-
H
L
F
Q
--
P
L
--------
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
70.16
19%
-86
* C3 *
3WFO
4
?
A:
[24-448]
---------------------
F
D
D
V
A
K
V
L
-
P
R
E
----
H
Y
C
F
I
V
G
G
W
V
R
D
R
I
L
G
E
P
V
GY
N
I
D
V
D
F
L
T
T
A
D
P
V
E
L
A
K
N
F
-
A
-------
K
R
-----
I
G
G
H
F
F
V
----
F
E
----------P
T
I
A
S
V
V
L
-
H
L
PP
Y
R
Y
R
F
D
F
S
P
L
K
G
K
------------
D
L
E
K
--
A
-----
L
I
E
D
L
K
E
R
D
F
T
A
N
A
I
A
V
N
-
L
-
D
D
V
L
SIGA
K
Q
T
I
----
V
Y
D
P
T
G
G
I
K
D
L
E
Q
G
L
L
R
P
V
--
S
I
E
N
L
K
R
D
P
V
R
V
L
R
G
F
R
I
A
I
E
K
---
N
L
---
Q
L
T
E
D
F
Y
E
F
V
K
E
D
P
--
R
--
I
V
L
K
S
A
V
E
R
I
T
H
E
L
F
K
I
M
K
E
K
T
A
H
K
V
I
R
E
L
Y
E
Y
-
G
V
L
E
A
I
I
P
--------
E
I
G
R
L
R
E
V
K
DP
L
D
E
--
H
T
L
K
T
L
E
Y
L
E
Q
V
I
E
D
RAKYLS
A
E
L
L
E
N
FGKKRVLGEF
T
--
D
V
-------
E
L
L
K
W
G
------
A
L
-
F
-----
H
D
I
G
K
PQTFVTFYE
H
D
K
V
G
A
Q
I
V
---
R
E
I
---
G
E
R
L
R
W
G
D
E
A
T
E
F
V
A
K
L
V
R
H
H
L
R
P
F
-----
F
L
R
-------
E
A
F
K
K
GEL
K
R
R
G
M
A
N
F
W
R
E
C
G
D
I
-
A
P
H
L
F
L
L
S
I
A
D
A
M
A
S
G
D
E
-
E
E
D
I
K
A
L
M
E
T
I
A
E
L
E
S
F
N
R
N
E
M
-
K
-------------------------------------------------------------
52
Fugue
70.14
27%
-72
- C3 -
1OU5
-
TRNT1_HUMAN
A:
[-1-354]
----K
M
K
L
Q
S
P
E
F
Q
S
L
F
T
-
E
G
L
K
S
L
T
E
L
F
V
K
E
N
----
H
E
L
R
I
A
G
G
A
V
R
D
L
L
N
G
V
K
P
---
Q
D
I
D
F
A
T
T
A
T
P
T
Q
M
K
E
M
F
-
Q
-------
S
A
G
I
R
M
I
N
----
N
R
----
G
E
K
H
-------
G
--
T
I
T
A
R
L
-
H
----
E
E
N
F
E
I
T
T
L
R
--------------
I
F
T
T
--
D
-----
W
Q
K
D
A
E
R
R
D
L
T
I
N
S
M
F
L
G
-
F
-
D
---------
G
T
----
L
F
D
Y
F
N
G
Y
E
D
L
K
N
K
K
V
R
F
V
G
H
A
K
Q
R
I
Q
E
D
Y
L
R
I
L
R
Y
F
R
F
Y
G
R
I
---
V
D
KPG
D
H
D
P
E
T
L
E
A
I
A
E
N
A
--
K
--
G
L
A
G
I
S
G
E
R
I
W
V
E
L
K
K
I
L
V
G
N
H
V
N
H
L
I
H
L
I
Y
D
L
-
D
V
A
P
Y
I
G
L
--------
P
A
N
A
S
L
E
E
F
-------
D
-------
K
V
---------------------------
S
--
K
N
VDGFSPK
P
V
T
L
L
A
------
S
L
F
K
-----
V
Q
D
D
V
---------------------
T
K
L
---
D
L
R
L
K
I
A
K
E
---------------------------------------
E
K
N
L
G
L
F
I
V
K
N
R
K
D
L
I
------------------------------
K
A
T
D
----
S
S
D
P
L
K
P
Y
Q
D
-
F
I
I
D
S
R
E
P
------------
D
A
T
T
R
V
C
E
L
L
K
Y
Q
G
E
-
H
C
L
L
K
E
M
Q
Q
W
S
I
-------
33
HHSearch
70.03
18%
-82
- C3 -
3WFP
1
?
A:
[6-354]
-----------------
L
-
S
Y
F
D
D
V
A
K
V
L
-
P
R
E
----
H
Y
C
F
I
V
G
G
W
V
R
D
R
I
L
G
E
P
V
GY
N
I
D
V
D
F
L
T
T
A
D
P
V
E
L
A
K
N
F
-
A
-------
K
R
-----
I
GG
H
F
F
V
----
F
E
K
R
G
FLIK
R
P
T
--
I
A
S
V
V
L
-
H
L
PP
Y
R
Y
R
F
D
F
S
P
L
K
G
K
------------
D
L
E
K
--
A
-----
L
I
E
D
L
K
E
R
D
F
T
A
N
A
I
A
V
N
-
L
-
D
D
V
L
SIGAKQ
T
I
----
V
Y
D
P
T
G
G
I
K
D
L
E
Q
G
L
L
R
P
V
--
S
I
E
N
L
K
R
D
P
V
R
V
L
R
G
F
R
I
A
I
E
K
---
N
L
---
Q
L
T
E
D
F
Y
E
F
V
K
E
D
P
--
R
--
I
V
L
K
S
A
V
E
R
I
T
H
E
L
F
K
I
M
K
E
K
T
A
H
K
V
I
R
E
L
Y
E
Y
-
G
V
L
E
A
I
I
P
--------
E
I
G
R
L
R
E
V
K
DP
L
D
E
--
H
T
L
K
T
L
E
Y
L
E
Q
V
I
E
D
RAKYLS
A
E
L
L
E
N
FGKKRVLGEF
T
--
D
V
-------
E
L
L
K
W
G
------
A
L
-
F
-----
H
D
I
G
K
PQTFVTFYE
H
D
K
V
G
A
Q
I
V
---
R
E
I
---
G
E
R
L
R
W
G
D
E
A
T
E
F
V
A
K
L
V
R
H
H
L
R
P
F
-----
F
L
R
E
A
F
K
K
GE
L
-------
K
R
R
G
M
A
N
F
W
R
E
C
G
D
I
-
A
P
H
L
F
L
L
S
I
A
D
A
M
-------------------------------------------------------------------------------------------
5
PsiBlast_PDB
69.70
31%
-93
- C3 -
3AQM
1
?
A:
[15-249]
--------------
K
D
I
S
-
E
N
A
L
K
V
M
Y
R
L
N
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
P
---
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
-
R
-------
N
C
-----
R
----
L
V
----
G
R
R
F
-------
R
--
L
A
H
V
M
F
-
G
----
P
E
I
I
E
V
A
T
F
R
G
--------------------NIFGS
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
-
V
-
A
D--------
F
T
----
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
---
G
M
---
R
I
S
P
E
T
A
E
P
I
P
R
L
A
--
T
--
L
L
N
D
I
P
P
A
R
L
F
E
E
S
L
K
L
L
Q
A
G
Y
G
Y
E
T
Y
K
L
L
C
E
Y
-
H
L
F
Q
--
P
L
--------
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
69.40
33%
-92
- C3 -
1OU5
-
TRNT1_HUMAN
A:
[9-277]
--------------
Q
S
L
F
T
E
G
L
K
S
L
T
E
L
F
V
K
E
N
----
H
E
L
R
I
A
G
G
A
V
R
D
L
L
N
G
V
K
P
---
Q
D
I
D
F
A
T
T
A
T
P
T
Q
M
K
E
M
F
Q
S
-------
A
G
-----
I
----
R
M
I
N
N
R
G
E
K
H
-------
G
--
T
I
T
A
R
L
-
H
----
E
E
N
F
E
I
T
T
L
R
I
--------------
F
T
T
--
D
-----
W
Q
K
D
A
E
R
R
D
L
T
I
N
S
M
F
L
G
-
F
-
D
---------
G
T
----
L
F
D
Y
F
N
G
Y
E
D
L
K
N
K
K
V
R
F
V
G
H
A
K
Q
R
I
Q
E
D
Y
L
R
I
L
R
Y
F
R
F
Y
G
R
I
VDK
P
G
---
D
H
D
P
E
T
L
E
A
I
A
E
N
A
--
K
--
G
L
A
G
I
S
G
E
R
I
W
V
E
L
K
K
I
L
V
G
N
H
V
----
N
H
L
I
H
L
I
Y
D
L
D
V
A
P
Y
IGLPANAS
L
E
E
F
D
K
V
S
K
-------
N
-------
V
D
GF-------------------------
S
--
P
K
-------
P
V
T
L
L
A
------
S
L
F
K
-----
V
Q
D
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
68.76
20%
-66
- C3 -
3H38
-
?
A:
[13-424]
--------------
E
R
V
D
-
P
K
I
L
N
L
F
R
L
L
G
K
F
G
D
E
V
N
M
P
V
Y
V
V
G
G
F
V
R
D
L
L
L
G
I
K
N
---
L
D
I
D
I
V
V
E
G
N
A
L
E
F
A
E
Y
A
-
K
-------
R
F
-----
L
P
G
K
L
V
K
----
H
D
K
F
-------
M
--
T
A
S
L
F
L
K
G
----
G
L
R
I
D
I
A
T
A
R
L
E
Y
Y
E
S
P
A
K
L
P
D
-
V
E
-
M
S
--
T
-----
I
K
K
D
L
Y
R
R
D
F
T
I
N
A
M
A
I
K
-
L
-
N
PKDF-----
G
L
----
L
I
D
F
F
G
G
Y
R
D
L
K
E
G
V
I
R
V
L
--
H
T
L
S
F
V
D
D
P
T
R
I
L
R
A
I
R
F
E
Q
R
F
---
D
F
---
R
I
E
E
T
T
E
R
L
L
K
Q
A
V
E
E
G
--
Y
L
E
R
T
T
G
P
R
L
R
Q
E
L
E
K
I
L
E
E
K
N
P
L
K
S
I
R
R
M
A
Q
F
-
D
V
I
K
H
L
F
P
--------
K
T
Y
Y
T
P
S
M
D
E
K
M
E
---
N
-------
L
F
R
N
I
P
W
V
E
E
-------------------
N
--
F
G
-------
E
V
D
R
F
Y
------
A
V
-
L
-----
H
V
F
L
E
FYD
D
E
S
W
--------------
K
E
V
---
R
D
R
Y
S
L
R
R
N
L
I
N
E
I
R
H
V
E
K
S
A
P
A
L
L
-----
E
M
L
-------
S
E
RV----
P
A
S
F
V
Y
P
L
V
K
G
V
S
N
E
T
I
C
H
--
F
L
A
Y
L
S
G
------------
E
K
E
G
---
L
F
K
----
S
Y
L
L
K
I
K
N
T
K
L
E
K
I
N
G
E
Y
L
I
R
-
K
G
I
T
S
G
K
I
I
G
E
V
L
E
K
I
L
M
K
K
L
D
G
D
T
R
D
E
E
E
I
-
L
E
E
V
L
A
S
L
----
25
PsiBlast_CBE
63.78
34%
-83
- C3 -
3AQL
2
?
B:
[15-204]
--------------
K
D
I
S
-
E
N
A
L
K
V
M
Y
R
L
N
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
P
---
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
-
R
-------
N
C
-----
R
----
L
V
----
G
R
R
F
-------
R
--
L
A
H
V
M
F
-
G
----
P
E
I
I
E
V
A
T
F
R
G
--------------------NIFGS
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
-
V
-
A
D--------
F
T
----
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
---
G
M
---
R
I
S
P
E
T
A
E
P
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
62.86
34%
-86
- C3 -
3AQN
1
?
B:
[15-204]
--------------
K
D
I
S
-
E
N
A
L
K
V
M
Y
R
L
N
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
P
---
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
-
R
-------
N
C
-----
R
----
L
V
----
G
R
R
F
-------
R
--
L
A
H
V
M
F
-
G
----
P
E
I
I
E
V
A
T
F
R
G
--------------------NIFGS
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
-
V
-
A
D--------
F
T
----
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
---
G
M
---
R
I
S
P
E
T
A
E
P
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
62.01
34%
-72
- C3 -
3AQK
-
?
A:
[31-220]
--------------
K
D
I
S
-
E
N
A
L
K
V
M
Y
R
L
N
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
P
---
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
-
R
-------
N
C
-----
R
----
L
V
----
G
R
R
F
-------
R
--
L
A
H
V
M
F
-
G
----
P
E
I
I
E
V
A
T
F
R
---------------------NIFGS
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
-
V
-
A
D--------
F
T
----
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
---
G
M
---
R
I
S
P
E
T
A
E
P
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
Fugue
61.80
19%
-74
- C3 -
1VFG
1
?
A:
[1-351]
-----------------------
M
V
G
Q
I
A
K
E
M
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
V
---
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
-------
R
R
H
G
V
N
-
V
----
H
P
----
F
P
E
F
-------
G
--
T
A
H
L
K
I
-
G
----
K
L
K
L
E
F
A
T
A
R
R
E
T
V
E
P
A
-------------
S
-----
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
-
V
-
N
---------
L
E
DYG
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
H
--
P
V
S
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
---
N
F
---
K
L
S
R
S
T
E
K
L
L
K
Q
A
V
--
N
L
G
L
L
K
E
A
P
R
G
R
L
I
N
E
I
K
L
A
L
R
E
D
R
F
L
E
I
L
E
L
Y
R
K
Y
-
R
V
L
E
E
I
--------------------------------------------------------------------------------------------------------------------------------
I
E
G
F
Q
W
N
E
K
V
L
Q
K
L
Y
A
L
R
K
V
V
D
W
-
H
-----
A
L
E
-------
F
-------
S
E
E
R
I
D
-----------
Y
G
W
L
Y
L
L
I
L
I
S
N
-
L
D
Y
E
R
G
K
H
F
L
E
E
M
S
A
P
S
W
V
R
----
E
T
Y
K
F
M
K
F
K
L
-
G
S
L
K
E
E
L
K
K
A
K
E
N
Y
E
V
Y
R
L
L
K
P
L
H
T
S
V
L
L
L
L
M
L
E
E
E
L
K
E
K
I
K
L
Y
L
E
K
L
R
K
V
K
L
P-
8
PsiBlast_PDB
61.66
34%
-91
- C3 -
3AQN
2
?
A:
[15-204]
--------------
K
D
I
S
-
E
N
A
L
K
V
M
Y
R
L
N
K
A
G
----
Y
E
A
W
L
V
G
G
G
V
R
D
L
L
L
G
K
K
P
---
K
D
F
D
V
T
T
N
A
T
P
E
Q
V
R
K
L
F
-
R
-------
N
C
-----
R
----
L
V
----
G
R
R
F
-------
R
--
L
A
H
V
M
F
-
G
----
P
E
I
I
E
V
A
T
F
R
G
--------------------NIFGS
I
E
E
D
A
Q
R
R
D
F
T
I
N
S
L
Y
Y
S
-
V
-
A
D--------
F
T
----
V
R
D
Y
V
G
G
M
K
D
L
K
D
G
V
I
R
L
I
G
N
P
E
T
R
Y
R
E
D
P
V
R
M
L
R
A
V
R
F
A
A
K
L
---
G
M
---
R
I
S
P
E
T
A
E
P
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
55.23
31%
-66
- C3 -
4WC6
1
?
A:
[7-189]
-----------------------------
K
E
M
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
V
---
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
H
G
V
N
V
H
P
-----
F
----
P
-------
E
F
-------
G
--
T
A
H
L
K
I
-
G
----
K
L
K
L
E
F
A
T
A
R
R
E
----
T
----------
E
PA
S
-----
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
-
V
-
N
---------
L
E
DYG
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
H
P
V
S
--
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
---
N
F
---
K
L
S
R
S
T
-
E
K
L
L
K
Q
A
--
V
--
N
L
G
L
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
55.06
31%
-66
- C3 -
4WC1
1
?
B:
[7-205]
-----------------------------
K
E
M
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
V
---
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
RRHGVNV
H
P
-----
F
----
P
-------
E
F
-------
G
--
T
A
H
L
K
I
-
G
----
K
L
K
L
E
F
A
T
A
R
R
E
----------------PA
S
-----
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
-
V
-
N
---------
L
E
DYGT
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
H
P
V
S
--
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
---
N
F
---
K
L
S
R
S
T
-
E
K
L
L
K
Q
A
--
V
--
N
L
G
L
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
54.88
31%
-67
- C3 -
4WC4
1
?
A:
[7-189]
-----------------------------
K
E
M
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
V
---
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
H
G
V
N
V
H
P
-----
F
----
P
-------
E
F
-------
G
--
T
A
H
L
K
I
-
G
----
K
L
K
L
E
F
A
T
A
R
R
E
----
T
----------
E
PA
S
-----
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
-
V
-
N
---------
L
E
DYG
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
H
P
V
S
--
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
---
N
F
---
K
L
S
R
S
T
-
E
K
L
L
K
Q
A
--
V
--
N
L
G
L
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
54.57
31%
-67
- C3 -
4WC5
1
?
A:
[7-189]
-----------------------------
K
E
M
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
V
---
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
H
G
V
N
V
H
P
-----
F
----
P
-------
E
F
-------
G
--
T
A
H
L
K
I
-
G
----
K
L
K
L
E
F
A
T
A
R
R
E
----
T
----------
E
PA
S
-----
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
-
V
-
N
---------
L
E
DYG
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
H
P
V
S
--
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
---
N
F
---
K
L
S
R
S
T
-
E
K
L
L
K
Q
A
--
V
--
N
L
G
L
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
54.36
31%
-70
- C3 -
4WC0
1
?
A:
[7-191]
-----------------------------
K
E
M
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
V
---
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
H
G
V
N
V
H
P
-----
F
----
P
-------
E
F
-------
G
--
T
A
H
L
K
I
-
G
----
K
L
K
L
E
F
A
T
A
R
R
E
----------------PA
S
-----
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
-
V
-
N
---------
L
E
DYG
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
H
P
V
S
--
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
---
N
F
---
K
L
S
R
S
T
-
E
K
L
L
K
Q
A
--
V
--
N
L
G
L
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
54.14
31%
-66
- C3 -
4WC1
1
?
A:
[7-191]
-----------------------------
K
E
M
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
V
---
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
H
G
V
N
V
H
P
-----
F
----
P
-------
E
F
-------
G
--
T
A
H
L
K
I
-
G
----
K
L
K
L
E
F
A
T
A
R
R
E
----------------PA
S
-----
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
-
V
-
N
---------
L
E
DYG
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
H
P
V
S
--
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
---
N
F
---
K
L
S
R
S
T
-
E
K
L
L
K
Q
A
--
V
--
N
L
G
L
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
54.08
31%
-66
- C3 -
4WC7
1
?
A:
[7-189]
-----------------------------
K
E
M
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
V
---
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
H
G
V
N
V
H
P
-----
F
----
P
-------
E
F
-------
G
--
T
A
H
L
K
I
-
G
----
K
L
K
L
E
F
A
T
A
R
R
E
----
T
----------
E
PA
S
-----
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
-
V
-
N
---------
L
E
DYG
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
H
P
V
S
--
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
---
N
F
---
K
L
S
R
S
T
-
E
K
L
L
K
Q
A
--
V
--
N
L
G
L
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
54.06
31%
-68
- C3 -
1VFG
1
?
B:
[7-208]
-----------------------------
K
E
M
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
V
---
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
RRHGVNV
H
P
-----
F
----
P
-------
E
F
-------
G
--
T
A
H
L
K
I
-
G
----
K
L
K
L
E
F
A
T
A
R
R
E
----
T
---------
V
E
PA
S
-----
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
-
V
-
N
---------
L
E
DYGT
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
H
P
V
S
--
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
---
N
F
---
K
L
S
R
S
T
-
E
K
L
L
K
Q
A
--
V
--
N
L
G
L
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
53.73
31%
-66
- C3 -
4WC2
1
?
A:
[7-189]
-----------------------------
K
E
M
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
V
---
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
H
G
V
N
V
H
P
-----
F
----
P
-------
E
F
-------
G
--
T
A
H
L
K
I
-
G
----
K
L
K
L
E
F
A
T
A
R
R
E
----
T
----------
E
PA
S
-----
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
-
V
-
N
---------
L
E
DYG
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
H
P
V
S
--
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
---
N
F
---
K
L
S
R
S
T
-
E
K
L
L
K
Q
A
--
V
--
N
L
G
L
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
53.46
31%
-66
- C3 -
4WC0
1
?
B:
[7-205]
-----------------------------
K
E
M
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
V
---
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
RRHGVNV
H
P
-----
F
----
P
-------
E
F
-------
G
--
T
A
H
L
K
I
-
G
----
K
L
K
L
E
F
A
T
A
R
R
E
----------------PA
S
-----
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
-
V
-
N
---------
L
E
DYGT
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
H
P
V
S
--
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
---
N
F
---
K
L
S
R
S
T
-
E
K
L
L
K
Q
A
--
V
--
N
L
G
L
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
53.25
31%
-69
- C3 -
1VFG
1
?
A:
[7-185]
-----------------------------
K
E
M
G
----
L
R
A
Y
I
V
G
G
V
V
R
D
I
L
L
G
K
E
V
---
W
D
V
D
F
V
V
E
G
N
A
I
E
L
A
K
E
L
-
A
R
R
H
G
V
N
V
H
P
-----
F
----
P
-------
E
F
-------
G
--
T
A
H
L
K
I
-
G
----
K
L
K
L
E
F
A
T
A
R
R
E
----
T
---------
V
E
PA
S
-----
L
K
E
D
L
I
R
R
D
F
T
I
N
A
M
A
I
S
-
V
-
N
---------
L
E
DYG
T
L
I
D
Y
F
G
G
L
R
D
L
K
D
K
V
I
R
V
L
H
P
V
S
--
F
I
E
D
P
V
R
I
L
R
A
L
R
F
A
G
R
L
---
N
F
---
K
L
S
R
S
T
-
E
K
L
L
K
Q
A
--
V
--
N
L
G
L
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------