@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1331: (2016-03-24 )
MQKNILKSGIALSELGLGCMSLGTDLKKAEQIIDCAVENGITYFDTADMYDKGINESVVGKALLKYQQRDDIFIGTKVGNRLTKDGSTTWDPSKSYIKEAVKGSLKRLGIDHIDLYQLHGGTIDDPLDETISAFDELKQEGIIRAYGISSIRPNVIDYYLKHSQIETIMSQFNLIDNRPESLLDAIHNNDVKVLARGPVSKGLLTSNSVNVLDNKFKDGIFDYSHDELGETIASIKEIESNLSALTFSYLTSHDVLGSIIVGASSVDQLKENIENYHTKVGLDQIKTARARVKDLEYTNHLV
Atome Classification :
(20 SA)
......-...10.......-.--20--...-------...--...30--........40........50-.-------.-------.......60....--.-.-..70.......---.80..--..---...-.90..--......100.......110.......------------120...-----------------....130.......140.......150.-......---160--.------.--.......170-.......--.180------------.-........190.......200...---------...-.210.......-220----...----.---------------.---...230.....---..240-----.---------------........250.......260.......270.....-..280.......290.......300
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
Q
K
N
I
L
-
K
SG
I
A
L
S
E
LG
L
G
-
C
--
M
---
S
LG-------
T
D
L
--
K
K
A
E
Q
--
I
I
D
C
A
V
ENG
I
T
YFDT
A
D
M
Y
--D-------K-------GI
N
E
S
V
V
G
K
A
L
L
K
--Y-Q-QRD
D
I
F
I
GTKV---G
N
R
LT--KD---GST-TWD
P
S
--
K
S
Y
I
K
E
A
V
K
G
S
L
K
RLGIDH
I
D
L
Y
Q
LH------------GGTID
D
-----------------
P
L
D
E
T
I
S
A
F
D
E
L
K
Q
EG
I
I
R
A
YGISSIR
P
-
N
V
I
D
Y
Y
---
L
----
K
------
H
--
S
Q
I
E
T
I
M
S
Q
--
F
NLIDNR--
P
E
--------------
S
-
L
L
D
A
I
HNN
D
V
K
V
L
ARGPVSKGLLT---------SNS-
V
N
V
L
D
N
K
FKDG-IF-----DY
S
----
H
---------------
D
---
E
L
G
E
T
I
A
S
I
K
E
---
I
E
S
-------
N
---------------
L
S
A
L
T
F
S
Y
L
T
S
H
D
V
L
G
S
I
I
VGA
S
S
V
D
Q
L
K
E
N
I
E
N
Y
H
-
T
KV
G
L
D
Q
I
K
T
A
R
A
R
V
K
DLEYTNHLV
1
PsiBlast_PDB
93.72
52%
-111
- C4 -
1YNP
11
?
A:
[23-288]
-
K
R
Q
L
G
-
T
S
D
L
H
V
S
E
L
G
F
G
-
C
--
M
---
S
L
G
-------
T
D
E
--
T
K
A
R
R
--
I
M
D
E
V
L
E
L
G
I
N
Y
L
D
T
A
D
L
Y
--
N
-------
Q
-------
G
L
N
E
Q
F
V
G
K
A
L
K
G
------
R
R
Q
D
I
I
L
A
T
K
V
-----------------------
S
--
K
A
Y
I
K
E
A
V
K
D
S
L
R
R
L
Q
T
D
Y
I
D
L
Y
Q
L
H
------------
G
G
T
I
D
D
-----------------
P
I
D
E
T
I
E
A
F
E
E
L
K
Q
E
G
V
I
R
Y
Y
G
I
S
S
I
R
P
-
N
V
I
K
E
Y
---
L
----
K
------
R
--
S
N
I
V
S
I
M
M
Q
--
Y
S
I
L
D
R
R
--
P
E
--------------
E
-
W
F
P
L
I
Q
E
H
G
V
S
V
V
V
R
G
P
V
A
R
G
L
L
S
---------
R
R
P
-
L
-----
P
E
G
E
G
-
Y
L
-----
N
Y
R
----
Y
---------------
D
---
E
L
K
L
L
R
E
S
L
P
----
T
D
R
-------
P
---------------
L
H
E
L
A
L
Q
Y
C
L
A
H
D
V
V
A
T
V
A
A
G
A
S
S
I
D
Q
V
K
A
N
V
Q
-----------------------------
2
PsiBlast_PDB
91.47
52%
-107
- C4 -
1YNQ
9
?
A:
[23-288]
-
K
R
Q
L
G
-
T
S
D
L
H
V
S
E
L
G
F
G
-
C
--
M
---
S
L
G
-------
T
D
E
--
T
K
A
R
R
--
I
M
D
E
V
L
E
L
G
I
N
Y
L
D
T
A
D
L
Y
--
N
-------
Q
-------
G
L
N
E
Q
F
V
G
K
A
L
K
G
------
R
R
Q
D
I
I
L
A
T
K
V
-----------------
W
-
W
W
D
P
S
--
K
A
Y
I
K
E
A
V
K
D
S
L
R
R
L
Q
T
D
Y
I
D
L
Y
Q
L
H
------------
G
G
T
I
D
D
-----------------
P
I
D
E
T
I
E
A
F
E
E
L
K
Q
E
G
V
I
R
Y
Y
G
I
S
S
I
R
P
-
N
V
I
K
E
Y
---
L
----
K
------
R
--
S
N
I
V
S
I
M
M
Q
--
Y
S
I
L
D
R
R
--
P
E
--------------
E
-
W
F
P
L
I
Q
E
H
G
V
S
V
V
V
R
G
P
V
A
R
G
L
L
S
---------
R
R
P
-
L
-----
P
E
G
E
G
-
Y
L
-----
N
Y
R
----
Y
---------------
D
---
E
L
K
L
L
R
E
S
L
P
----
T
D
R
-------
P
---------------
L
H
E
L
A
L
Q
Y
C
L
A
H
D
V
V
A
T
V
A
A
G
A
S
S
I
D
Q
V
K
A
N
V
Q
-----------------------------
22
PsiBlast_CBE
88.69
52%
-91
- C4 -
1YNP
6
?
B:
[23-288]
-
K
R
Q
L
G
-
T
S
D
L
H
V
S
E
L
G
F
G
-
C
--
M
---
S
L
G
-------
T
D
E
--
T
K
A
R
R
--
I
M
D
E
V
L
E
L
G
I
N
Y
L
D
T
A
D
L
Y
--
N
-------
Q
-------
G
L
N
E
Q
F
V
G
K
A
L
K
G
------
R
R
Q
D
I
I
L
A
T
K
V
---
G
N
R
F
E
Q
G
K
E
---
G
-
W
-
W
W
D
P
S
--
K
A
Y
I
K
E
A
V
K
D
S
L
R
R
L
Q
T
D
Y
I
D
L
Y
Q
L
H
------------
G
G
T
I
D
D
-----------------
P
I
D
E
T
I
E
A
F
E
E
L
K
Q
E
G
V
I
R
Y
Y
G
I
S
S
I
R
P
-
N
V
I
K
E
Y
---
L
----
K
------
R
--
S
N
I
V
S
I
M
M
Q
--
Y
S
I
L
D
R
R
--
P
E
--------------
E
-
W
F
P
L
I
Q
E
H
G
V
S
V
V
V
R
G
P
V
A
R
G
L
L
S
---------
R
R
P
-
L
-----
P
E
G
E
G
-
Y
L
-----
N
Y
R
----
Y
---------------
D
---
E
L
K
L
L
R
E
S
L
P
----
T
D
R
-------
P
---------------
L
H
E
L
A
L
Q
Y
C
L
A
H
D
V
V
A
T
V
A
A
G
A
S
S
I
D
Q
V
K
A
N
V
Q
-----------------------------
33
HHSearch
87.88
50%
-93
- C4 -
1YNP
13
?
A:
[21-315]
M
K
K
R
Q
L
G
T
S
D
L
H
V
S
E
L
G
F
G
-
C
--
M
---
S
L
G
-------
T
D
E
--
T
K
A
R
R
--
I
M
D
E
V
L
E
L
G
I
N
Y
L
D
T
A
D
L
Y
--
N
-------
Q
-------
G
L
N
E
Q
F
V
G
K
A
L
K
G
------
R
R
Q
D
I
I
L
A
T
K
V
-----------------------
S
--
K
A
Y
I
K
E
A
V
K
D
S
L
R
R
L
Q
T
D
Y
I
D
L
Y
Q
L
H
------------
G
G
T
I
D
D
-----------------
P
I
D
E
T
I
E
A
F
E
E
L
K
Q
E
G
V
I
R
Y
Y
G
I
S
S
I
R
P
-
N
V
I
K
E
Y
---
L
----
K
------
R
--
S
N
I
V
S
I
M
M
Q
--
Y
S
I
L
D
R
R
--
P
E
--------------
E
-
W
F
P
L
I
Q
E
H
G
V
S
V
V
V
R
G
P
V
A
R
G
L
L
S
R--------
R
P
L
P
E
G
E
G
Y
--
L
N
-------------------------------------
Y
R
Y
D
E
L
K
L
L
R
E
S
LP
T
D
R
-------
P
---------------
L
H
E
L
A
L
Q
Y
C
L
A
H
D
V
V
A
T
V
A
A
G
A
S
S
I
D
Q
V
K
A
N
V
Q
A
V
E
A
T
P
L
T
A
E
E
R
Q
H
I
Q
K
L
A
K
A
A
V
Y
E
Q
H
--
21
PsiBlast_CBE
87.56
52%
-93
- C4 -
1YNQ
10
?
B:
[23-288]
-
K
R
Q
L
G
-
T
S
D
L
H
V
S
E
L
G
F
G
-
C
--
M
---
S
L
G
-------
T
D
E
--
T
K
A
R
R
--
I
M
D
E
V
L
E
L
G
I
N
Y
L
D
T
A
D
L
Y
--
N
-------
Q
-------
G
L
N
E
Q
F
V
G
K
A
L
K
G
------
R
R
Q
D
I
I
L
A
T
K
V
---
G
N
R
F
E
QG
K
E
---
G
-
W
-
W
W
D
P
S
--
K
A
Y
I
K
E
A
V
K
D
S
L
R
R
L
Q
T
D
Y
I
D
L
Y
Q
L
H
------------
G
G
T
I
D
D
-----------------
P
I
D
E
T
I
E
A
F
E
E
L
K
Q
E
G
V
I
R
Y
Y
G
I
S
S
I
R
P
-
N
V
I
K
E
Y
---
L
----
K
------
R
--
S
N
I
V
S
I
M
M
Q
--
Y
S
I
L
D
R
R
--
P
E
--------------
E
-
W
F
P
L
I
Q
E
H
G
V
S
V
V
V
R
G
P
V
A
R
G
L
L
S
---------
R
R
P
-
L
-----
P
E
G
E
G
-
Y
L
-----
N
Y
R
----
Y
---------------
D
---
E
L
K
L
L
R
E
S
L
P
----
T
D
R
-------
P
---------------
L
H
E
L
A
L
Q
Y
C
L
A
H
D
V
V
A
T
V
A
A
G
A
S
S
I
D
Q
V
K
A
N
V
Q
-----------------------------
9
PsiBlast_PDB
72.17
27%
-89
- C4 -
1LQA
1
TAS_ECOLI
A:
[5-329]
---
R
I
P
-
H
S
S
L
E
V
S
T
L
G
L
G
-
T
--
M
---
T
F
G
-------
E
Q
N
--
S
E
A
D
A
H
A
Q
L
D
Y
A
V
A
Q
G
I
N
L
I
D
V
A
E
M
Y
--
P
VPPRPET
Q
-------
G
L
T
E
T
Y
V
G
N
W
L
A
K
--
H
-
G
-
S
R
E
K
L
I
I
A
S
K
V
S
--
G
P
S
R
N
--
N
D
---
K
G
I
-
R
P
D
Q
A
LD
R
K
N
I
R
E
A
L
H
D
S
L
K
R
L
Q
T
D
Y
L
D
L
Y
Q
V
H
WPQRPTNCFGKL
G
Y
S
W
T
D
SAPAV------------
S
L
L
D
T
L
D
A
L
A
E
Y
Q
R
A
G
K
I
R
Y
I
G
V
S
N
E
T
A
-
F
G
V
M
R
Y
---
L
H
L
A
D
K
------
H
DL
P
R
I
V
T
I
Q
N
P
--
Y
S
L
L
N
R
S
--
F
E
V-------------
G
-
L
A
E
V
S
Q
Y
E
G
V
E
L
L
A
Y
S
C
L
G
F
G
T
L
T
GKYLNGAKP
A
G
A
-
R
N
T
L
F
S
R
F
T
----------
R
Y
S
----
G
---------------
E
---
Q
T
Q
K
A
V
A
A
Y
V
D
---
I
A
R
R
H
GL---
D
---------------
P
A
Q
M
A
L
A
F
V
R
R
Q
P
F
V
A
S
T
L
L
G
A
T
T
M
D
Q
L
K
T
N
I
E
S
L
H
-
L
E
L
S
E
D
-------------------
17
PsiBlast_PDB
70.42
25%
-75
- C4 -
2R9R
1
KCAB2_RAT
A:
[6-300]
--
R
N
L
G
-
K
S
G
L
R
V
S
C
L
G
L
G
T
W
--
V
---
T
F
G
-------
G
Q
I
T
D
E
M
A
E
H
--
L
M
T
L
A
Y
D
N
G
I
N
L
F
D
T
A
E
V
Y
--
A
-------
A
-------
G
K
A
E
V
V
L
G
N
I
I
K
K
--
K
G
W
-
R
R
S
S
L
V
I
T
T
K
I
F
WG
G
K
A
E
T
--
E
R
---
G
L
------
S
--
R
K
H
I
I
E
G
L
K
A
S
L
E
R
L
Q
L
E
Y
V
D
V
V
F
A
N
------------
R
P
D
P
N
T
-----------------
P
M
E
E
T
V
R
A
M
T
H
V
I
N
Q
G
M
A
M
Y
W
G
T
S
R
W
S
S
M
E
I
M
E
A
Y
----------------------
S
V
A
R
Q
--
F
N
L
I
P
P
I
--
C
E
Q
A
E
Y
H
MFQREKVEV
Q
-
L
P
E
L
F
H
K
I
G
V
G
A
M
T
W
S
P
L
A
C
G
------------------
I
V
S
G
K
Y
D
S
G
-
I
P
-----
P
Y
S
----
R
ASLKGY
Q
W
L
K
D
K
I
L
S
E
---
E
G
R
R
Q
Q
A
K
L
K
E
---
L
Q
A
I
A
E
R
L
GC
T
---------------
L
P
Q
L
A
I
A
W
C
L
R
N
E
G
V
S
S
V
L
L
G
A
S
N
A
E
Q
L
M
E
N
I
------------------------------
19
PsiBlast_PDB
69.98
25%
-77
- C4 -
4JTA
1
KCAB2_RAT
A:
[6-300]
--
R
N
L
G
-
K
S
G
L
R
V
S
C
L
G
L
G
T
W
--
V
---
T
F
G
-------
G
Q
I
T
D
E
M
A
E
H
--
L
M
T
L
A
Y
D
N
G
I
N
L
F
D
T
A
E
V
Y
--
A
-------
A
-------
G
K
A
E
V
V
L
G
N
I
I
K
K
--
K
G
W
-
R
R
S
S
L
V
I
T
T
K
I
F
WG
G
K
A
E
T
--
E
R
---
G
L
------
S
--
R
K
H
I
I
E
G
L
K
A
S
L
E
R
L
Q
L
E
Y
V
D
V
V
F
A
N
------------
R
P
D
P
N
T
-----------------
P
M
E
E
T
V
R
A
M
T
H
V
I
N
Q
G
M
A
M
Y
W
G
T
S
R
W
S
S
M
E
I
M
E
A
Y
----------------------
S
V
A
R
Q
--
F
N
L
I
P
P
I
--
C
E
Q
A
E
Y
H
MFQREKVEV
Q
-
L
P
E
L
F
H
K
I
G
V
G
A
M
T
W
S
P
L
A
C
G
------------------
I
V
S
G
K
Y
D
S
G
-
I
P
-----
P
Y
S
----
R
ASLKGY
Q
W
L
K
D
K
I
L
S
E
---
E
G
R
R
Q
Q
A
K
L
K
E
---
L
Q
A
I
A
E
R
L
GC
T
---------------
L
P
Q
L
A
I
A
W
C
L
R
N
E
G
V
S
S
V
L
L
G
A
S
N
A
E
Q
L
M
E
N
I
------------------------------
13
PsiBlast_PDB
69.94
27%
-91
- C4 -
4AST
-
GPR_ECOLI
A:
[20-313]
-------
K
S
G
L
R
L
P
A
L
S
L
G
-
L
--
W
H--
N
F
G
HV-----
N
A
L
--
E
S
Q
R
A
--
I
L
R
K
A
F
D
L
G
I
T
H
F
D
L
A
N
N
Y
GP
P
-------
P
-------
G
S
A
E
E
N
F
G
R
L
L
R
E
DF
A
-
A
-
Y
R
D
E
L
I
I
S
T
K
A
---
G
Y
D
M
W
--
P
----
G
P
Y
-
G
S
G
G
S
--
R
K
Y
L
L
A
S
L
D
Q
S
L
K
R
M
G
L
E
Y
V
D
I
F
Y
S
H
------------
R
V
D
E
N
T
-----------------
P
M
E
E
T
A
S
A
L
A
H
A
V
Q
S
G
K
A
L
Y
V
G
I
S
S
Y
S
P
-
E
R
T
Q
K
M
V
E
L
L
----
R
------
E
--
W
K
I
P
L
L
I
H
Q
P
S
Y
N
L
L
N
R
W
V
D
K
S
--------------
G
-
L
L
D
T
L
Q
N
N
G
V
G
C
I
A
F
T
P
L
A
Q
G
L
L
T
-------------------------------------------------------------------------
A
N
L
-------
N
S
L
R
L
L
N
E
M
A
Q
Q
R
GQS
M
A
Q
M
A
L
S
W
L
L
K
D
D
R
V
T
S
V
L
I
G
A
S
R
A
E
Q
L
E
E
N
V
Q
-----------------------------
4
PsiBlast_PDB
69.78
24%
-89
- C4 -
1PYF
2
IOLS_BACSU
A:
[8-291]
-------
K
S
D
L
Q
V
F
P
I
G
L
G
-
T
--
N
---
A
V
G
GHNLYPN
L
N
E
--
E
T
G
K
E
--
L
V
R
E
A
I
R
N
G
V
T
M
L
D
T
A
Y
I
Y
--
G
-------
I
-------
G
R
S
E
E
L
I
G
E
V
L
R
E
--
F
-
N
--
R
E
D
V
V
I
A
T
K
A
---
A
H
R
----
K
Q
---
G
N
D
F
V
F
D
N
S
--
P
D
F
L
K
K
S
V
D
E
S
L
K
R
L
N
T
D
Y
I
D
L
F
Y
I
H
------------
F
P
D
E
H
T
-----------------
P
K
D
E
A
V
N
A
L
N
E
M
K
K
A
G
K
I
R
S
I
G
V
S
N
F
S
L
-
E
Q
L
K
E
A
---
N
----
K
------
D
--
G
L
V
D
V
L
Q
G
E
--
Y
N
L
L
N
R
E
--
A
E
K-------------
T
-
F
F
P
Y
T
K
E
H
N
I
S
F
I
P
Y
F
P
L
V
S
G
L
L
A
---------
G
K
Y
-
T
E
--
D
T
T
F
P
E
G
-
D
L
RNEQE
H
F
K
----
G
---------------
E
---
R
F
K
E
N
I
R
K
V
N
K
---
L
A
P
I
A
E
K
H
NV
D
---------------
I
P
H
I
V
L
A
W
Y
L
A
R
P
E
I
D
I
L
I
P
G
A
K
R
A
D
Q
L
I
D
N
I
K
-----------------------------
11
PsiBlast_PDB
69.61
27%
-90
- C4 -
4AUB
2
GPR_ECOLI
A:
[40-333]
-------
K
S
G
L
R
L
P
A
L
S
L
G
-
L
--
W
H--
N
F
G
HV-----
N
A
L
--
E
S
Q
R
A
--
I
L
R
K
A
F
D
L
G
I
T
H
F
D
L
A
N
N
Y
GP
P
-------
P
-------
G
S
A
E
E
N
F
G
R
L
L
R
E
DF
A
-
A
-
Y
R
D
E
L
I
I
S
T
K
A
---
G
Y
D
M
W
--
P
----
G
P
Y
-
G
S
G
G
S
--
R
K
Y
L
L
A
S
L
D
Q
S
L
K
R
M
G
L
E
Y
V
D
I
F
Y
S
H
------------
R
V
D
E
N
T
-----------------
P
M
E
E
T
A
S
A
L
A
H
A
V
Q
S
G
K
A
L
Y
V
G
I
S
S
Y
S
P
-
E
R
T
Q
K
M
V
E
L
L
----
R
------
E
--
W
K
I
P
L
L
I
H
Q
P
S
Y
N
L
L
N
R
W
V
D
K
S
--------------
G
-
L
L
D
T
L
Q
N
N
G
V
G
C
I
A
F
T
P
L
A
Q
G
L
L
T
---------
G
K
--------------------------------------------------------
L
T
E
---
A
N
L
-------
N
S
L
R
L
L
N
E
M
A
Q
Q
R
GQS
M
A
Q
M
A
L
S
W
L
L
K
D
D
R
V
T
S
V
L
I
G
A
S
R
A
E
Q
L
E
E
N
V
Q
-----------------------------
15
PsiBlast_PDB
69.47
26%
-77
- C4 -
1ZSX
4
KCAB2_HUMAN
A:
[27-321]
--
R
N
L
G
-
K
S
G
L
R
V
S
C
L
G
L
G
T
W
--
V
---
T
F
G
-------
G
Q
I
T
D
E
M
A
E
Q
--
L
M
T
L
A
Y
D
N
G
I
N
L
F
D
T
A
E
V
Y
--
A
-------
A
-------
G
K
A
E
V
V
L
G
N
I
I
K
K
--
K
G
W
-
R
R
S
S
L
V
I
T
T
K
I
F
WG
G
K
A
E
T
--
E
R
---
G
L
------
S
--
R
K
H
I
I
E
G
L
K
A
S
L
E
R
L
Q
L
E
Y
V
D
V
V
F
A
N
------------
R
P
D
P
N
T
-----------------
P
M
E
E
T
V
R
A
M
T
H
V
I
N
Q
G
M
A
M
Y
W
G
T
S
R
W
S
S
M
E
I
M
E
A
Y
----------------------
S
V
A
R
Q
--
F
N
L
T
P
P
I
--
C
E
Q
A
E
Y
H
MFQREKVEV
Q
-
L
P
E
L
F
H
K
I
G
V
G
A
M
T
W
S
P
L
A
C
G
------------------
I
V
S
G
K
Y
D
S
G
-
I
P
-----
P
Y
S
----
R
ASLKGY
Q
W
L
K
D
K
I
L
S
E
---
E
G
R
R
Q
Q
A
K
L
K
E
---
L
Q
A
I
A
E
R
L
GC
T
---------------
L
P
Q
L
A
I
A
W
C
L
R
N
E
G
V
S
S
V
L
L
G
A
S
N
A
D
Q
L
M
E
N
I
------------------------------
10
PsiBlast_PDB
69.25
26%
-76
- C4 -
3EB4
2
KCAB2_RAT
A:
[6-300]
--
R
N
L
G
-
K
S
G
L
R
V
S
C
L
G
L
G
T
W
--
V
---
T
F
G
-------
G
Q
I
T
D
E
M
A
E
H
--
L
M
T
L
A
Y
D
N
G
I
N
L
F
D
T
A
E
V
Y
--
A
-------
A
-------
G
K
A
E
V
V
L
G
N
I
I
K
K
--
K
G
W
-
R
R
S
S
L
V
I
T
T
K
I
F
WG
G
K
A
E
T
--
E
R
---
G
L
------
S
--
R
K
H
I
I
E
G
L
K
A
S
L
E
R
L
Q
L
E
Y
V
D
V
V
F
A
N
------------
R
P
D
P
N
T
-----------------
P
M
E
E
T
V
R
A
M
T
H
V
I
N
Q
G
M
A
M
Y
W
G
T
S
R
W
S
S
M
E
I
M
E
A
Y
----------------------
S
V
A
R
Q
--
F
N
L
I
P
P
R
--
C
E
Q
A
E
Y
H
MFQREKVEV
Q
-
L
P
E
L
F
H
K
I
G
V
G
A
M
T
W
S
P
L
A
C
G
------------------
I
V
S
G
K
Y
D
S
G
-
I
P
-----
P
Y
S
----
R
ASLKGY
Q
W
L
K
D
K
I
L
S
E
---
E
G
R
R
Q
Q
A
K
L
K
E
---
L
Q
A
I
A
E
R
L
GC
T
---------------
L
P
Q
L
A
I
A
W
C
L
R
N
E
G
V
S
S
V
L
L
G
A
S
N
A
E
Q
L
M
E
N
I
------------------------------
5
PsiBlast_PDB
69.18
24%
-86
- C4 -
1PZ0
2
IOLS_BACSU
A:
[8-291]
-------
K
S
D
L
Q
V
F
P
I
G
L
G
-
T
--
N
---
A
V
G
GHNLYPN
L
N
E
--
E
T
G
K
E
--
L
V
R
E
A
I
R
N
G
V
T
M
L
D
T
A
Y
I
Y
--
G
-------
I
-------
G
R
S
E
E
L
I
G
E
V
L
R
E
--
F
-
N
--
R
E
D
V
V
I
A
T
K
A
---
A
H
R
----
K
Q
---
G
N
D
F
V
F
D
N
S
--
P
D
F
L
K
K
S
V
D
E
S
L
K
R
L
N
T
D
Y
I
D
L
F
Y
I
H
------------
F
P
D
E
H
T
-----------------
P
K
D
E
A
V
N
A
L
N
E
M
K
K
A
G
K
I
R
S
I
G
V
S
N
F
S
L
-
E
Q
L
K
E
A
---
N
----
K
------
D
--
G
L
V
D
V
L
Q
G
E
--
Y
N
L
L
N
R
E
--
A
E
K-------------
T
-
F
F
P
Y
T
K
E
H
N
I
S
F
I
P
Y
F
P
L
V
S
G
L
L
A
---------
G
K
Y
-
T
E
--
D
T
T
F
P
E
G
-
D
L
RNEQE
H
F
K
----
G
---------------
E
---
R
F
K
E
N
I
R
K
V
N
K
---
L
A
P
I
A
E
K
H
NV
D
---------------
I
P
H
I
V
L
A
W
Y
L
A
R
P
E
I
D
I
L
I
P
G
A
K
R
A
D
Q
L
I
D
N
I
K
-----------------------------
20
PsiBlast_PDB
68.67
25%
-75
- C4 -
4JTC
1
KCAB2_RAT
A:
[6-300]
--
R
N
L
G
-
K
S
G
L
R
V
S
C
L
G
L
G
T
W
--
V
---
T
F
G
-------
G
Q
I
T
D
E
M
A
E
H
--
L
M
T
L
A
Y
D
N
G
I
N
L
F
D
T
A
E
V
Y
--
A
-------
A
-------
G
K
A
E
V
V
L
G
N
I
I
K
K
--
K
G
W
-
R
R
S
S
L
V
I
T
T
K
I
F
WG
G
K
A
E
T
--
E
R
---
G
L
------
S
--
R
K
H
I
I
E
G
L
K
A
S
L
E
R
L
Q
L
E
Y
V
D
V
V
F
A
N
------------
R
P
D
P
N
T
-----------------
P
M
E
E
T
V
R
A
M
T
H
V
I
N
Q
G
M
A
M
Y
W
G
T
S
R
W
S
S
M
E
I
M
E
A
Y
----------------------
S
V
A
R
Q
--
F
N
L
I
P
P
I
--
C
E
Q
A
E
Y
H
MFQREKVEV
Q
-
L
P
E
L
F
H
K
I
G
V
G
A
M
T
W
S
P
L
A
C
G
------------------
I
V
S
G
K
Y
D
S
G
-
I
P
-----
P
Y
S
----
R
ASLKGY
Q
W
L
K
D
K
I
L
S
E
---
E
G
R
R
Q
Q
A
K
L
K
E
---
L
Q
A
I
A
E
R
L
GC
T
---------------
L
P
Q
L
A
I
A
W
C
L
R
N
E
G
V
S
S
V
L
L
G
A
S
N
A
E
Q
L
M
E
N
I
------------------------------
16
PsiBlast_PDB
68.10
25%
-75
- C4 -
2A79
4
KCAB2_RAT
A:
[6-300]
--
R
N
L
G
-
K
S
G
L
R
V
S
C
L
G
L
G
T
W
--
V
---
T
F
G
-------
G
Q
I
T
D
E
M
A
E
H
--
L
M
T
L
A
Y
D
N
G
I
N
L
F
D
T
A
E
V
Y
--
A
-------
A
-------
G
K
A
E
V
V
L
G
N
I
I
K
K
--
K
G
W
-
R
R
S
S
L
V
I
T
T
K
I
F
WG
G
K
A
E
T
--
E
R
---
G
L
------
S
--
R
K
H
I
I
E
G
L
K
A
S
L
E
R
L
Q
L
E
Y
V
D
V
V
F
A
N
------------
R
P
D
P
N
T
-----------------
P
M
E
E
T
V
R
A
M
T
H
V
I
N
Q
G
M
A
M
Y
W
G
T
S
R
W
S
S
M
E
I
M
E
A
Y
----------------------
S
V
A
R
Q
--
F
N
L
I
P
P
I
--
C
E
Q
A
E
Y
H
MFQREKVEV
Q
-
L
P
E
L
F
H
K
I
G
V
G
A
M
T
W
S
P
L
A
C
G
------------------
I
V
S
G
K
Y
D
S
G
-
I
P
-----
P
Y
S
----
R
ASLKGY
Q
W
L
K
D
K
I
L
S
E
---
E
G
R
R
Q
Q
A
K
L
K
E
---
L
Q
A
I
A
E
R
L
GC
T
---------------
L
P
Q
L
A
I
A
W
C
L
R
N
E
G
V
S
S
V
L
L
G
A
S
N
A
E
Q
L
M
E
N
I
------------------------------
18
PsiBlast_PDB
68.02
25%
-78
- C4 -
3LNM
1
KCAB2_RAT
A:
[6-300]
--
R
N
L
G
-
K
S
G
L
R
V
S
C
L
G
L
G
T
W
--
V
---
T
F
G
-------
G
Q
I
T
D
E
M
A
E
H
--
L
M
T
L
A
Y
D
N
G
I
N
L
F
D
T
A
E
V
Y
--
A
-------
A
-------
G
K
A
E
V
V
L
G
N
I
I
K
K
--
K
G
W
-
R
R
S
S
L
V
I
T
T
K
I
F
WG
G
K
A
E
T
--
E
R
---
G
L
------
S
--
R
K
H
I
I
E
G
L
K
A
S
L
E
R
L
Q
L
E
Y
V
D
V
V
F
A
N
------------
R
P
D
P
N
T
-----------------
P
M
E
E
T
V
R
A
M
T
H
V
I
N
Q
G
M
A
M
Y
W
G
T
S
R
W
S
S
M
E
I
M
E
A
Y
----------------------
S
V
A
R
Q
--
F
N
L
I
P
P
I
--
C
E
Q
A
E
Y
H
MFQREKVEV
Q
-
L
P
E
L
F
H
K
I
G
V
G
A
M
T
W
S
P
L
A
C
G
------------------
I
V
S
G
K
Y
D
S
G
-
I
P
-----
P
Y
S
----
R
ASLKGY
Q
W
L
K
D
K
I
L
S
E
---
E
G
R
R
Q
Q
A
K
L
K
E
---
L
Q
A
I
A
E
R
L
GC
T
---------------
L
P
Q
L
A
I
A
W
C
L
R
N
E
G
V
S
S
V
L
L
G
A
S
N
A
E
Q
L
M
E
N
I
------------------------------
12
PsiBlast_PDB
67.55
27%
-88
- C4 -
3N6Q
1
GPR_ECOLI
A:
[20-313]
-------
K
S
G
L
R
L
P
A
L
S
L
G
-
L
--
W
H--
N
F
G
HV-----
N
A
L
--
E
S
Q
R
A
--
I
L
R
K
A
F
D
L
G
I
T
H
F
D
L
A
N
N
Y
GP
P
-------
P
-------
G
S
A
E
E
N
F
G
R
L
L
R
E
DF
A
-
A
-
Y
R
D
E
L
I
I
S
T
K
A
---
G
Y
D
M
W
--
P
----
G
P
Y
-
G
S
G
G
S
--
R
K
Y
L
L
A
S
L
D
Q
S
L
K
R
M
G
L
E
Y
V
D
I
F
Y
S
H
------------
R
V
D
E
N
T
-----------------
P
M
E
E
T
A
S
A
L
A
H
A
V
Q
S
G
K
A
L
Y
V
G
I
S
S
Y
S
P
-
E
R
T
Q
K
M
V
E
L
L
----
R
------
E
--
W
K
I
P
L
L
I
H
Q
P
S
Y
N
L
L
N
R
W
V
D
K
S
--------------
G
-
L
L
D
T
L
Q
N
N
G
V
G
C
I
A
F
T
P
L
A
Q
G
L
L
T
---------
G
K
Y
-
L
-----------------------------------------------------
L
T
E
---
A
N
L
-------
N
S
L
R
L
L
N
E
M
A
Q
Q
R
GQS
M
A
Q
M
A
L
S
W
L
L
K
D
D
R
V
T
S
V
L
I
G
A
S
R
A
E
Q
L
E
E
N
V
Q
-----------------------------
31
HHSearch
67.00
27%
-79
- C4 -
1LQA
1
TAS_ECOLI
A:
[1-344]
M
Q
Y
H
R
I
P
H
S
S
L
E
V
S
T
L
G
L
G
-
T
MT
F
---
G
E
Q
-------
N
S
E
--
A
D
A
H
A
--
Q
L
D
Y
A
V
A
Q
G
I
N
L
I
D
V
A
E
M
Y
--
P
-------
V
PPRPETQ
G
L
T
E
T
Y
V
G
N
W
L
A
K
--
H
-
G
-
S
R
E
K
L
I
I
A
S
K
V
---
S
G
P
S
R
--
N
N
DKG
I
R
P
-
D
Q
A
L
D
--
R
K
N
I
R
E
A
L
H
D
S
L
K
R
L
Q
T
D
Y
L
D
L
Y
Q
V
H
------------
W
P
Q
R
P
T
NCFGKL
G
Y
S
W
T
DSAPAV
S
L
L
D
T
L
D
A
L
A
E
Y
Q
R
A
G
K
I
R
Y
I
G
V
S
N
E
T
A
-
F
G
V
M
R
Y
---
L
----
H
L
A
D
K
H
D
L
--
P
R
I
V
T
I
Q
N
P
--
Y
S
L
L
N
R
S
--
F
E
--------------
V
G
L
A
E
V
S
Q
Y
E
G
V
E
L
L
A
Y
S
C
L
G
F
G
T
L
T
G--------
K
Y
L
N
G
A
K
P
A
G
-
A
R
N
T
L
F
S
-----
R
F
T
RYSG
E
---------------
Q
T
Q
-
K
A
V
A
A
Y
V
D
I
A
R
R
--
H
G
L
-------
D
---------------
P
A
Q
M
A
L
A
F
V
R
R
Q
P
F
V
A
S
T
L
L
G
A
T
T
M
D
Q
L
K
T
N
I
E
S
L
H
-
L
E
L
S
E
D
V
L
A
E
I
E
A
V
H
Q
V
Y
T
Y
P
----
36
HHSearch
64.99
27%
-80
- C4 -
3N6Q
1
GPR_ECOLI
A:
[13-338]
M
Q
Y
R
Y
C
G
K
S
G
L
R
L
P
A
L
S
L
G
-
L
--
W
HNF
G
H
V
-------
N
A
L
--
E
S
Q
R
A
--
I
L
R
K
A
F
D
L
G
I
T
H
F
D
L
A
N
N
Y
--
G
-------
P
PP-----
G
S
A
E
E
N
F
G
R
L
L
R
E
--
D
F
A
A
Y
R
D
E
L
I
I
S
T
K
A
---
G
Y
D
M
W
--
P
----
G
P
Y
-
G
S
G
G
S
--
R
K
Y
L
L
A
S
L
D
Q
S
L
K
R
M
G
L
E
Y
V
D
I
F
Y
S
H
------------
R
V
D
E
N
T
-----------------
P
M
E
E
T
A
S
A
L
A
H
A
V
Q
S
G
K
A
L
Y
V
G
I
S
S
Y
S
P
-
E
R
T
Q
K
M
---
V
----
E
L
L
R
E
W
-
K
--
I
P
L
L
I
H
Q
P
S
--
Y
N
L
L
N
R
W
--
V
D
K
S
------------
G
-
L
L
D
T
L
Q
N
N
G
V
G
C
I
A
F
T
P
L
A
Q
G
L
L
T
G--------
K
Y
L
----------------------
L
----
T
---------------
E
A
N
L
N
S
L
R
L
L
N
E
M
A
Q
Q
--
R
G
Q
-------
S
---------------
M
A
Q
M
A
L
S
W
L
L
K
D
D
R
V
T
S
V
L
I
G
A
S
R
A
E
Q
L
E
E
N
V
Q
A
L
N
N
L
T
F
S
T
K
E
L
A
Q
I
D
Q
H
I
A
D
G
E
L
N
----