@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1411: (2016-03-25 )
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW
Atome Classification :
(20 SA)
--.........10........-20.-........30....-....---40........50.---.......60-----........70--......-...80........90......----.-.100---.........110...-....120......--.130....-.---..140.......------150........160......---.170.......180-..----.-.....190.......200....--...210.......220...----....230....-...240--.......250.......-260.......270.......280.-.......290.......300.......310.......320...----------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--MIT
D
R
Q
L
S
I
L
N
A
I
V
E
D
Y
V
D
-F-G-QPVGS
K
T
L
I
E
RHNL-NVS
P
---
A
T
I
R
N
E
M
K
Q
L
E
D
L
---
N
Y
I
E
K
THSS-----SGR
S
P
S
Q
L
G
---
F
R
Y
Y
V
N
-
R
L
L
E
Q
TSH
Q
K
T
N
K
L
R
R
L
N
Q
L
L
----
V
-EN-----QY
D
V
S
S
A
L
T
Y
F
A
D
E
L
-SNIS
Q
Y
T
T
L
V
VHP--N
H
K
Q
D
I
IN-N---
V
H
L
I
RANP
N
L
V
I
------
M
-
V
I
V
FSSG
H
V
E
H
V
H
LASDI---PFSND
K
L
N
T
I
S
N
F
--
V
T
----
N
-
K
L
T
E
F
N
Q
N
L
Q
D
D
I
V
S
F
V
QS
E
Q
E
--
E
I
F
I
N
K
L
I
N
T
M
N
N
HISNQS----N
S
I
Y
MGG
K
V
K
L
-
I
D
ALNE--S
N
V
S
S
I
Q
P
I
L
Q
Y
I
E
S
N
R
-
I
A
E
L
L
Q
D
ISSP
N
I
N
V
K
IGNEID-D-SLSD
I
S
I
V
T
SQYHFDETLKG
Q
I
A
V
IG
P
T
A
M
H
Y
Q
N
V
I
Q
L
L
N
RIW----------------------------------------
42
Fugue
91.97
22%
-103
- C5 -
1STZ
-
HRCA_THEMA
A:
[14-336]
--
K
L
N
D
R
Q
R
K
V
L
Y
C
I
V
R
E
Y
I
E
-
N
-
K
-
K
P
V
S
S
Q
R
V
L
E
V
S
N
I
-
E
F
S
S
---
A
T
I
R
N
D
M
K
K
L
E
Y
L
---
G
Y
I
Y
Q
P
H
T
S
-----
A
G
R
I
P
T
D
K
G
---
L
R
F
Y
Y
E
-
E
M
L
K
I
S
K
E
T
S
E
A
D
-
L
A
V
E
T
F
K
----
S
-
M
P
-----
L
A
D
P
E
K
V
L
F
L
A
G
N
L
L
-
A
R
L
T
E
G
Y
V
L
I
E
R
P
--
N
T
R
D
L
K
I
L
-
R
---
V
M
L
I
P
V
S
E
D
Y
L
I
------
F
-
S
I
L
T
E
F
G
V
S
K
V
T
P
I
K
T
Q
E
---
R
L
N
W
E
E
I
E
R
Q
L
N
F
--
L
L
----
R
-
G
R
T
---------
V
G
E
V
L
M
G
K
I
E
--
S
L
K
G
S
G
F
L
R
L
I
E
S
L
I
G
E
T
V
----
E
R
Y
L
D
A
G
-----
L
E
N
L
L
K
--
D
E
T
L
T
L
E
D
I
R
N
L
L
E
E
V
K
-
D
Q
K
F
L
E
S
L
V
G
E
G
I
T
V
R
I
G
R
E
I
G
R
K
-
K
L
E
K
F
A
V
F
S
G
K
Y
F
K
G
E
S
P
I
G
S
V
Y
L
F
T
S
K
V
T
K
Y
D
R
N
H
R
V
F
E
Y
I
L
N
R
L
S
E
Y
F
T
S
T
S-----------------------------
21
HHSearch
89.67
22%
-104
- C5 -
1STZ
-
HRCA_THEMA
A:
[14-325]
--
K
L
N
D
R
Q
R
K
V
L
Y
C
I
V
R
E
Y
I
E
-
N
-
K
-
K
P
V
S
S
Q
R
V
L
E
V
S
N
I
-
E
F
S
S
---
A
T
I
R
N
D
M
K
K
L
E
Y
L
---
G
Y
I
Y
Q
P
H
T
S
-----
A
G
R
I
P
T
D
K
G
---
L
R
F
Y
Y
E
-
E
M
L
K
I
S
K
E
T
S
E
-
A
D
L
-
A
V
E
T
F
----
K
S
M
P
-----
L
A
D
P
E
K
V
L
F
L
A
G
N
L
L
-
A
R
L
T
E
G
Y
V
L
I
E
R
P
--
N
T
R
D
L
K
I
L
-
R
---
V
M
L
I
P
V
S
E
D
Y
L
I
------
F
-
S
I
L
T
E
F
G
V
S
K
V
T
P
I
K
T
Q
E
---
R
L
---
N
W
E
E
I
E
R
Q
--
L
N
F
L
LR
G
R
T
V
G
E
V
L
M
G
K
I
E
S
L
K
G
------
S
---
G
F
L
R
L
I
----
E
S
L
I
G
E
T
V
----
E
R
Y
L
D
A
G
L
E
N
L
-
L
K
D
E
T
L
--
T
-
L
E
D
I
R
N
L
L
E
E
V
K
D
Q
K
F
L
E
S
L
V
----
G
E
G
I
T
V
R
I
G
R
E
I
G
-
R
K
K
L
E
K
F
A
V
F
S
G
K
Y
F
K
G
E
S
P
I
G
S
V
Y
L
F
T
S
K
V
T
K
Y
D
R
N
H
R
V
F
E
Y
I
L
----------------------------------------
1
PsiBlast_PDB
81.83
23%
-76
- C5 -
1STZ
-
HRCA_THEMA
A:
[15-314]
---
L
N
D
R
Q
R
K
V
L
Y
C
I
V
R
E
Y
I
E
-
N
-
K
-
K
P
V
S
S
Q
R
V
L
E
V
S
N
I
-
E
F
S
S
---
A
T
I
R
N
D
M
K
K
L
E
Y
L
---
G
Y
I
Y
Q
P
H
T
S
-----
A
G
R
I
P
T
D
K
G
---
L
R
F
Y
Y
E
-
E
M
L
------
K
I
S
K
E
T
S
E
A
D
L
A
----
V
-
E
T
FKSMP
L
A
D
P
E
K
V
L
F
L
A
G
N
L
L
-
A
R
L
T
E
G
Y
V
L
I
E
R
P
--
N
T
R
D
L
K
I
L
-
R
---
V
M
L
I
P
V
S
E
D
Y
L
I
------
F
-
S
I
L
T
E
F
G
V
S
K
V
T
P
I
K
T
Q
E
---
R
L
N
W
E
E
I
E
R
Q
L
N
F
--
L
L
----
R
------
G
R
T
V
G
E
V
L
M
G
K
I
E
S
L
K
G
--
S
G
F
L
-
R
L
I
E
S
L
I
G
E
T
V
E
R
--------
Y
L
D
A
G
----
L
E
N
L
L
K
--
D
E
T
L
T
L
E
D
I
R
N
L
L
E
E
V
K
-
D
Q
K
F
L
E
S
L
V
G
E
G
I
T
V
R
I
G
R
E
I
G
R
K
-
K
L
E
K
F
A
V
F
S
G
K
Y
F
K
G
E
S
P
I
G
S
V
Y
L
F
T
S
K
V
T
K
Y
---------------------------------------------------
29
HHSearch
46.72
12%
-48
- C5 -
2LNB
-
ZBP1_HUMAN
A:
[17-66]
---
E
G
H
L
E
Q
R
I
L
Q
V
L
T
----
E
-
A
-
G
-
S
P
V
K
L
A
Q
L
V
K
E
--
C
-
Q
A
P
K
---
R
E
L
N
Q
V
L
Y
R
M
K
K
E
---
L
K
V
S
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
45.61
19%
-47
- C5 -
2PN6
-
?
A:
[1-63]
---
M
D
E
I
D
L
R
I
L
K
I
L
-----
Q
-
Y
-
N
-
A
K
Y
S
L
D
E
I
A
R
E
--
I
-
R
I
P
K
---
A
T
L
S
Y
R
I
K
K
L
E
K
D
---
G
V
I
K
G
Y
Y
-------
A
Y
I
N
P
A
S
L
N
---
L
D
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
45.59
13%
-28
- C4 -
3ISP
-
Y1985_MYCTU
A:
[5-296]
--
Q
L
D
G
P
Q
L
A
A
L
A
A
V
V
E
L
-----------
G
S
F
D
A
A
A
E
-
R
L
-
H
V
T
P
---
S
A
V
S
Q
R
I
K
S
L
E
Q
Q
V
GQ
V
L
V
V
R
E
K
P
C
-----
R
A
T
T
A
G
I
P
L
---
L
R
L
A
A
Q
-
T
A
L
L
E
S
E
A
L
A
E
M
G
A
S
L
-
K
R
T
R
----
I
-
T
I
-----
A
V
N
A
D
S
M
A
T
W
F
S
A
V
F
-
D
G
L
G
D
V
L
L
D
V
R
I
E
D
Q
D
H
S
A
R
L
L
R
-
E
GVA
M
G
A
V
T
T
E
R
N
P
V
P
------
G
-
C
R
V
H
P
L
G
E
M
R
Y
L
P
V
A
S
---------------
R
P
F
--
V
Q
----
R
-
H
L
S
D
G
F
T
A
A
A
A
A
K
A
P
S
L
A
W
N
R
D
--
D
G
L
Q
D
M
L
V
R
K
A
F
R
R
A
I
T
R
P
----
T
H
-
F
V
P
T
T
E
G
F
-
T
A
A
A
R
A
--
G
L
G
W
G
M
F
P
-
E
K
L
A
A
S
P
L
-
A
D
G
S
F
V
R
V
C
D
I
H
L
D
V
P
L
Y
W
Q
C
W
-
K
-
L
D
S
---------
P
I
I
A
R
I
T
D
T
V
R
A
A
A
S
G
L
Y
R
G
Q
--------------------------------------------------
35
HHSearch
44.87
25%
-42
- C5 -
2CG4
1
ASNC_ECOLI
A:
[6-68]
---
I
D
N
L
D
R
G
I
L
E
A
L
-----
M
-
G
-
N
-
A
R
T
A
Y
A
E
L
A
K
Q
--
F
-
G
V
S
P
---
E
T
I
H
V
R
V
E
K
M
K
Q
A
---
G
I
I
T
G
A
R
-------
I
D
V
S
P
K
Q
L
G
---
Y
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
44.69
24%
-59
- C5 -
2P5V
-
?
A:
[8-58]
---
L
D
K
T
D
I
K
I
L
Q
V
L
-----
Q
-
E
-
N
-
G
R
L
T
N
V
E
L
S
E
R
--
V
-
A
L
S
P
---
S
P
C
L
R
R
L
K
Q
L
E
D
A
---
G
I
V
R
Q
Y
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
42.34
24%
-45
- C5 -
1I1G
-
REG7_PYRFU
A:
[2-66]
---
I
D
E
R
D
K
I
I
L
E
I
L
E
------
K
-
D
-
A
R
T
P
F
T
E
I
A
K
K
--
L
-
G
I
S
E
---
T
A
V
R
K
R
V
K
A
L
E
E
K
---
G
I
I
E
G
Y
T
I
-------
K
I
N
P
K
K
L
G
---
Y
S
L
V
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
42.30
17%
-26
- C1 -
4OL8
2
YG31B_YEAST
A:
[24-461]
P
V
W
L
Q
Q
K
Y
R
E
I
I
R
N
D
L
P
P
P
V
K
-
H
-
D
I
E
I
K
P
G
A
R
L
P
R
L
Q
P
Y
-
H
V
T
E
K
N
E
Q
E
I
N
K
I
V
Q
K
L
L
D
N
---
K
F
I
V
P
S
K
S
P
------
C
S
S
P
V
V
L
V
P
KT
F
R
L
C
V
D
Y
R
T
L
N
K
A
T
I
S
D
P
F
P
L
P
R
I
D
N
L
L
S
R
IG
N
-
A
Q
-----
I
F
T
T
L
D
L
H
S
G
Y
H
Q
I
P
M
E
P
K
D
R
Y
K
T
A
F
V
T
P
--
S
G
K
Y
E
Y
T
V
M
P
---
F
G
L
V
N
A
P
S
T
F
A
R
------
Y
M
A
D
T
F
R
D
L
R
F
V
N
V
Y
L
D
D
I
L
---
I
F
S
E
S
P
E
E
H
W
K
H
L
D
T
V
L
----
E
-
R
L
K
N
E
N
L
I
V
K
K
K
K
C
K
F
E
E
T
E
F
L
G
Y
S
I
G
I
Q
K
I
A
P
L
Q
H
K
C
A
A
I
R
D
FPTP
K
T
V
K
Q
A
Q
R
F
L
G
M
I
N
Y
Y
R
R
FI
P
N
C
S
K
I
A
Q
P
I
T
E
K
Q
D
K
A
-
I
D
K
L
K
D
A
P
F
N
N
K
A
N
Y
R
L
T
--
T
D
-
A
-
S
K
D
G
I
G
A
V
L
E
E
V
D
N
K
N
K
L
V
G
V
V
G
Y
F
S
K
S
L
E
Y
P
A
G
E
L
E
L
L
G
I
I
K
A
L
H
H
F
RYMLHGKH
F
T
L
R
T
N
HA
R
R
V
Q
R
W
L
D
D
L
A
T
Y
D
F
T
L
E
Y
32
HHSearch
41.87
13%
-28
- C5 -
3I71
2
EUTK_ECOLI
A:
[4-52]
------
S
A
D
E
L
L
A
L
L
T
----
S
-
V
-
R
-
Q
G
M
T
A
G
E
V
A
A
H
--
F
-
G
W
P
L
---
E
K
A
R
N
A
L
E
Q
L
F
S
A
---
G
T
L
R
K
R
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
40.18
19%
-11
* C5 *
2JT1
-
?
A:
[1-71]
--
M
S
E
S
I
V
T
K
I
I
S
I
V
Q
E
R
Q
N
M
D
D
-
G
-
A
P
V
K
T
R
D
I
A
D
A
--
A
-
G
L
S
I
---
Y
Q
V
R
L
Y
L
E
Q
L
H
D
V
---
G
V
L
E
K
V
N
A
G
-----
K
G
V
P
G
L
W
R
L
---
L
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
39.35
15%
-16
- C5 -
2OBP
1
?
A:
[14-89]
---
I
D
P
A
I
V
E
V
L
L
V
L
R
E
A
G
I
E
-
N
G
A
-
T
P
W
S
L
P
K
I
A
K
R
--
A
-
Q
L
P
M
---
S
V
L
R
R
V
L
T
Q
L
Q
A
A
---
G
L
A
D
V
S
V
E
A
DG
R
--
G
H
A
S
L
T
Q
E
G
---
A
A
L
A
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
38.88
18%
-34
- C5 -
2B0L
-
CODY_BACSU
A:
[179-234]
---
L
S
Y
S
E
L
E
A
I
E
H
I
F
E
E
L
D
G
-
N
-
E
-
G
L
L
V
A
S
K
I
A
D
R
--
V
-
G
I
T
R
---
S
V
I
V
N
A
L
R
K
L
E
S
A
---
G
V
I
E
S
R
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
38.87
14%
-35
- C5 -
3BJ6
1
?
A:
[38-112]
---
V
T
V
G
Q
R
A
I
L
E
G
L
-----
S
-
L
-
T
-
P
G
A
T
A
P
Q
L
G
A
A
--
L
-
Q
M
K
R
---
Q
Y
I
S
R
I
L
Q
E
V
Q
R
A
---
G
L
I
E
R
R
T
N
P
EHARS
H
R
Y
W
L
T
P
R
G
---
E
A
I
I
T
A
-
I
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
38.76
14%
-37
- C5 -
2CYY
3
REG6_PYRHO
A:
[4-68]
--
P
L
D
E
I
D
K
K
I
I
K
I
L
-----
Q
-
N
-
D
-
G
K
A
P
L
R
E
I
S
K
I
--
T
-
G
L
A
E
---
S
T
I
H
E
R
I
R
K
L
R
E
S
---
G
V
I
K
K
F
T
A
-------
I
I
D
P
E
A
L
G
---
Y
S
M
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
38.66
14%
-40
- C5 -
1BJA
1
MOTA_BPT4
A:
[14-79]
---
L
N
E
K
T
A
T
I
L
I
T
I
A
------
K
-
K
-
D
F
I
T
A
A
E
V
R
E
V
--
H
P
D
L
G
N
---
A
V
V
N
S
N
I
G
V
L
I
K
K
---
G
L
V
E
K
S
G
-------
D
G
L
I
I
T
G
E
A
---
Q
D
I
I
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
37.72
26%
-56
- C5 -
3BIT
1
SPT16_YEAST
A:
[45-135]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
N
P
--
Y
Q
K
T
T
I
L
H
-
N
---
W
L
L
S
Y
E
F
P
A
T
L
I
A
L
V
PG
K
V
-
I
I
I
T
S
S
A
K
A
K
H
L
Q
K
A
I
D
L
F
K
D
P
E
S
K
I
T
L
E
L
W
Q
R
----
N
----
N
-
K
E
P
E
L
N
K
K
L
F
D
D
V
I
A
L
I
N
S
A
G
K
--
T
V
G
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
37.64
11%
-16
- C4 -
1JHF
1
LEXA_ECOLI
A:
[2-198]
-K
A
L
T
A
R
Q
Q
E
V
F
D
L
I
R
D
H
I
S
Q
-
T
-
G
-
M
P
P
T
R
A
E
I
A
Q
R
L
G
F
-
R
-
S
P
---
N
A
A
E
E
H
L
K
A
L
A
R
K
---
G
V
I
E
I
V
S
G
A
-----
S
R
G
I
R
L
L
Q
E
---
E
E
E
G
L
P
-
L
V
G
R
V
A
A
D
E
P
L
L
A
Q
Q
H
---------
I
-
E
G
-----
H
Y
Q
V
D
P
S
L
F
K
P
N
A
D
F
-
L
L
R
V
S
G
M
S
M
K
D
I
G
--
I
M
D
G
D
L
L
A
-
V
---
H
K
T
Q
D
V
R
N
G
Q
V
V
------
V
-
A
R
I
D
D
E
V
T
V
K
R
L
K
K
Q
G
N
K
---
V
E
L
L
P
E
N
S
E
F
K
P
I
--
V
V
----
D
-
L
R
Q
Q
-
S
F
T
I
E
G
L
A
V
G
V
I
R
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
37.15
26%
-54
- C5 -
3BIQ
1
SPT16_YEAST
A:
[45-135]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
N
P
--
Y
Q
K
T
T
I
L
H
-
N
---
W
L
L
S
Y
E
F
P
A
T
L
I
A
L
V
PG
K
V
-
I
I
I
T
S
S
A
K
A
K
H
L
Q
K
A
I
D
L
F
KD--
S
K
I
T
L
E
L
W
Q
R
----
N
----
N
-
K
E
P
E
L
N
K
K
L
F
D
D
V
I
A
L
I
N
S
A
G
K
--
T
V
G
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------