@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1448: (2016-03-25 )
MIDQQTIYQYIQNGKIEEALQALFGNIEEDPTIIENYINAGIVLADANEIEKAERFFQKALTIDPKNGVVFYNLANVYYNQQRYQEAIKLYQQALQTEIEQVDCNYMIGMAFNQLESFKLALPYLMTAAELDKDKDAEVQFQYGLVLCQLEMFNEAITQLKHVLTIDKNHVDARYNLGLALFMKNEDIDEAITHFKEAVTIDPKHLLSQHALKTFTKMKEEE
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20........30........40........50........60........-70........80........90........100.........110.......120.......130.------.-..---------...140.-......150.......160.....-------..170.......180.......190.......200.......210.......220-------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MI
D
Q
Q
T
I
Y
Q
Y
I
QNG
K
I
E
E
A
L
Q
A
L
FGNIEE
D
P
T
I
I
E
N
YINA
G
I
V
LA
D
A
N
E
I
E
K
A
E
R
F
F
Q
K
A
L
T
IDPKN
G
V
-
V
F
Y
N
L
A
N
V
Y
Y
N
Q
Q
R
Y
Q
E
A
I
K
L
Y
Q
Q
A
L
Q
T
E
I
E
--QVDC
N
Y
M
I
G
M
A
F
N
Q
L
E
S
F
K
L
A
L
P
Y
L
M
T
A
A
ELDK------D-KD---------A
E
V
Q
F
Q
Y
-
G
L
V
L
C
Q
L
E
M
F
N
E
A
I
T
Q
L
K
H
V
L
T
ID-------KNHV
D
A
R
YNL
G
L
A
L
F
M
KNE
D
I
D
E
A
I
T
H
F
K
E
AVTI
D
P
K
H
L
L
S
Q
H
A
L
K
T
F
T
K
MKEEE-------------------------------------------------------------
48
HHSearch
82.85
25%
-85
- C1 -
1W3B
-
OGT1_HUMAN
A:
[176-380]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
C
V
F
N
A
Q
G
E
I
W
L
A
I
H
H
F
E
K
A
V
T
L
D
P
N
F
L
D
A
Y
I
N
L
G
N
V
L
K
E
A
R
I
F
D
R
A
V
A
A
Y
L
R
A
L
S
L
S
P
N
H
A
V
-
V
H
G
N
L
A
C
V
Y
Y
E
Q
G
L
I
D
L
A
I
D
T
Y
R
R
A
I
E
L
Q
P
H
--
F
P
D
A
Y
C
N
L
A
N
A
L
K
E
K
G
S
V
A
E
A
E
D
C
Y
N
T
A
L
R
L
C
P
--------
T
H
---------
A
D
S
L
N
N
L
-
A
N
I
K
R
E
Q
G
N
I
E
E
A
V
R
L
Y
R
K
A
L
E
V
F
-------
P
E
F
A
A
A
H
S
N
L
A
S
V
-
L
Q
Q
Q
G
K
L
Q
E
A
L
M
H
Y
K
E
A
I
R
I
S
P
T
F
A
D
A
Y
S
N
M
G
----------------------------------------------------------------------
1
PsiBlast_PDB
79.53
36%
-97
- C1 -
2Q7F
-
YRRB_BACSU
A:
[43-235]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
E
A
F
T
K
A
I
E
E
N
K
E
D
A
I
P
Y
I
N
F
A
N
L
L
S
S
V
N
E
L
E
R
A
L
A
F
Y
D
K
A
L
E
L
D
S
S
A
A
T
-
A
Y
Y
G
A
G
N
V
Y
V
V
K
E
M
Y
K
E
A
K
D
M
F
E
K
A
L
R
A
G
M
E
--
N
G
D
L
F
Y
M
L
G
T
V
L
V
K
L
E
Q
P
K
L
A
L
P
Y
L
Q
R
A
V
E
L
N
E
------
N
--
D
---------
T
E
A
R
F
Q
F
-
G
M
C
L
A
N
E
G
M
L
D
E
A
L
S
Q
F
A
A
V
T
E
Q
D
-------
P
G
H
A
D
A
F
Y
N
A
G
V
T
Y
A
Y
K
-
E
N
R
E
K
A
L
E
M
L
D
K
A
I
D
I
Q
P
D
H
M
L
A
L
H
A
K
K
----------------------------------------------------------------------
36
HHSearch
78.49
36%
-96
- C1 -
2Q7F
-
YRRB_BACSU
A:
[43-236]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
E
A
F
T
K
A
I
E
E
N
K
E
D
A
I
P
Y
I
N
F
A
N
L
L
S
S
V
N
E
L
E
R
A
L
A
F
Y
D
K
A
L
E
L
D
S
S
A
A
T
-
A
Y
Y
G
A
G
N
V
Y
V
V
K
E
M
Y
K
E
A
K
D
M
F
E
K
A
L
R
A
G
M
E
--
N
G
D
L
F
Y
M
L
G
T
V
L
V
K
L
E
Q
P
K
L
A
L
P
Y
L
Q
R
A
V
E
L
N
E
--------
N
D
---------
T
E
A
R
F
Q
F
-
G
M
C
L
A
N
E
G
M
L
D
E
A
L
S
Q
F
A
A
V
T
E
Q
D
-------
P
G
H
A
D
A
F
Y
N
A
G
V
T
-
Y
A
Y
K
E
N
R
E
K
A
L
E
M
L
D
K
A
I
D
I
Q
P
D
H
M
L
A
L
H
A
K
K
L
---------------------------------------------------------------------
15
PsiBlast_PDB
75.28
24%
-96
- C1 -
3AS5
1
?
A:
[11-174]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
R
D
K
G
I
S
H
A
K
A
G
R
Y
S
Q
A
V
M
L
L
E
Q
V
Y
D
A
D
A
F
D
V
D
-
V
A
L
H
L
G
I
A
Y
V
K
T
G
A
V
D
R
G
T
E
L
L
E
R
S
L
A
D
A
P
D
--
N
V
K
V
A
T
V
L
G
L
T
Y
V
Q
V
Q
K
Y
D
L
A
V
P
L
L
I
K
V
A
E
A
N
P
--------
I
N
---------
F
N
V
R
F
R
L
-
G
V
A
L
D
N
L
G
R
F
D
E
A
I
D
S
F
K
I
A
L
G
L
R
-------
P
N
E
G
K
V
H
R
A
I
A
F
S
-
Y
E
Q
M
G
R
H
E
E
A
L
P
H
F
K
K
A
N
E
L
D
---------------------------------------------------------------------------------
12
PsiBlast_PDB
73.42
24%
-95
- C1 -
3ASG
-
?
A:
[49-212]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
R
D
K
G
I
S
H
A
K
A
G
R
Y
S
Q
A
V
M
L
L
E
Q
V
Y
D
A
D
A
F
D
V
D
-
V
A
L
H
L
G
I
A
Y
V
K
T
G
A
V
D
R
G
T
E
L
L
E
R
S
L
A
D
A
P
D
--
N
V
K
V
A
T
V
L
G
L
T
Y
V
Q
V
Q
K
Y
D
L
A
V
P
L
L
I
K
V
A
E
A
N
P
--------
I
N
---------
F
N
V
R
F
R
L
-
G
V
A
L
K
N
L
G
R
F
D
E
A
I
D
S
F
K
I
A
L
G
L
R
-------
P
N
E
G
K
V
H
R
A
I
A
F
S
-
Y
E
Q
M
G
R
H
E
E
A
L
P
H
F
K
K
A
N
E
L
D
---------------------------------------------------------------------------------
6
PsiBlast_PDB
71.66
26%
-91
- C1 -
1W3B
-
OGT1_HUMAN
A:
[77-268]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
K
E
R
G
Q
L
Q
E
A
I
E
H
Y
R
H
A
L
R
L
K
P
D
F
I
D
G
Y
I
N
L
A
A
A
L
V
A
A
G
D
M
E
G
A
V
Q
A
Y
V
S
A
L
Q
Y
N
P
D
L
Y
C
-
V
R
S
D
L
G
N
L
L
K
A
L
G
R
L
E
E
A
K
A
C
Y
L
K
A
I
E
T
Q
P
N
--
F
A
V
A
W
S
N
L
G
C
V
F
N
A
Q
G
E
I
W
L
A
I
H
H
F
E
K
A
V
T
L
D
P
------
N
F
L
D
---------
A
Y
I
N
L
---
G
N
V
L
K
E
A
R
I
F
D
R
A
V
A
A
Y
L
R
A
L
S
L
S
-------
P
N
H
A
V
V
H
G
N
L
A
-
C
V
Y
Y
E
Q
G
L
I
D
L
A
I
D
T
Y
R
R
A
I
E
L
Q
P
--------------------------------------------------------------------------------
52
Fugue
71.36
18%
-88
- C1 -
2XPI
4
CUT9_SCHPO
A:
[45-595]
NSQLSTLTISPMTYLAS
R
E
D
Y
L
R
L
W
R
H
D
A
L
M
Q
QQ
Y
K
C
A
A
F
V
G
E
K
V
L
D
I
TGN
P
N
D
A
F
W
L
A
Q
V
Y
C
C
T
GD
Y
A
R
A
K
C
L
L
T
KED
L
Y
N
R
S
S
A
C
R
Y
L
A
A
F
C
L
V
K
L
YD
W
Q
G
A
L
N
L
L
GETNPFRMQDGGIK
L
E
A
S
M
C
Y
L
R
G
Q
V
Y
T
N
L
SN
F
D
R
A
K
E
C
Y
K
E
A
L
M
V
DAKC
Y
E
A
F
D
Q
L
V
S
N
HLLT
A
D
E
E
W
D
L
V
L
K
LNYSTYSKED
A
A
F
L
R
S
L
Y
M
L
K
LNKTSH
E
D
E
L
R
R
A
E
D
Y
L
S
S
INGLEKS
S
D
L
L
L
C
K
A
D
T
L
F
V
R
SR
F
I
D
V
L
A
I
T
T
K
I
L
E
I
DPYNLDV
Y
P
L
H
L
A
S
L
H
E
S
GE
K
N
K
L
Y
L
I
S
N
D
L
V
D
R
HPEK
A
V
T
W
L
A
V
G
I
Y
Y
L
C
V
N
K
I
S
E
A
R
R
Y
F
S
K
S
S
T
M
D
P
Q
F
G
P
A
W
I
G
F
A
H
S
F
A
I
E
G
E
H
D
Q
A
I
S
A
Y
T
T
A
A
R
L
F
Q
G
T
H
L
-
P
Y
L
F
L
G
M
Q
H
M
Q
L
G
N
I
L
L
A
N
E
Y
L
Q
S
S
Y
A
L
F
Q
Y
--
D
P
L
L
L
N
E
L
G
V
V
A
F
N
K
S
D
M
Q
T
A
I
N
H
F
Q
N
A
L
L
L
V
K
K
T
QSNE
K
-
P
W
---------
A
A
T
W
A
N
L
-
G
H
A
Y
R
K
L
K
M
Y
D
A
A
I
D
A
L
N
Q
G
L
L
L
S
-------
T
N
D
A
N
V
H
T
A
I
A
L
V
Y
L
H
K
K
-
I
P
G
L
A
I
T
H
L
H
E
S
L
A
I
S
P
N
E
I
M
A
S
D
L
L
K
R
A
L
E
------------------------------------------------------------------
51
HHSearch
71.20
21%
-85
- C1 -
2XPI
1
CUT9_SCHPO
A:
[346-554]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
S
L
H
E
S
G
E
K
N
K
L
Y
L
I
S
N
D
L
V
D
R
H
P
E
K
A
V
T
W
L
A
V
G
I
Y
Y
L
C
V
N
K
I
S
E
A
R
R
Y
F
S
K
S
S
T
M
D
P
Q
F
G
P
-
A
W
I
G
F
A
H
S
F
A
I
E
G
E
H
D
Q
A
I
S
A
Y
T
T
A
A
R
L
F
Q
G
--
T
H
L
P
Y
L
F
L
G
M
Q
H
M
Q
L
G
N
I
L
L
A
N
E
Y
L
Q
S
S
Y
A
L
F
Q
--------
Y
D
---------
P
L
L
L
N
E
L
-
G
V
V
A
F
N
K
S
D
M
Q
T
A
I
N
H
F
Q
N
A
L
L
L
V
K
K
T
QSNE
K
P
W
A
A
T
W
A
N
L
G
H
A
-
Y
R
K
L
K
M
Y
D
A
A
I
D
A
L
N
Q
G
L
L
L
S
T
N
D
A
N
V
H
T
-------------------------------------------------------------------------
13
PsiBlast_PDB
70.43
24%
-91
- C1 -
3ASH
3
?
A:
[11-174]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
R
D
K
G
I
S
H
A
K
A
G
R
Y
S
Q
A
V
M
L
L
E
Q
V
Y
D
A
D
A
F
D
V
D
-
V
A
L
H
L
G
I
A
Y
V
K
T
G
A
V
D
R
G
T
E
L
L
E
R
S
L
A
D
A
P
D
--
N
V
K
V
A
T
V
L
G
L
T
Y
V
Q
V
Q
K
Y
D
L
A
V
P
L
L
I
K
V
A
E
A
N
P
--------
I
N
---------
F
N
V
R
F
R
L
-
G
V
A
L
K
N
L
G
R
F
D
E
A
I
D
S
F
K
I
A
L
G
L
R
-------
P
N
E
G
K
V
H
R
A
I
A
F
S
-
Y
E
Q
M
G
R
H
E
E
A
L
P
H
F
K
K
A
N
E
L
D
---------------------------------------------------------------------------------
20
PsiBlast_PDB
69.26
22%
-94
- C1 -
3AS8
3
?
A:
[11-176]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
R
D
K
G
I
S
H
A
K
A
G
R
Y
S
E
A
V
V
M
L
E
Q
V
Y
D
A
D
A
F
D
V
E
-
V
A
L
H
L
G
I
A
Y
V
K
T
G
A
V
D
R
G
T
E
L
L
E
R
S
I
A
D
A
P
D
--
N
I
K
V
A
T
V
L
G
L
T
Y
V
Q
V
Q
K
Y
D
L
A
V
P
L
L
V
K
V
A
E
A
N
P
--------
V
N
---------
F
N
V
R
F
R
L
-
G
V
A
L
D
N
L
G
R
F
D
E
A
I
D
S
F
K
I
A
L
G
L
R
-------
P
N
E
G
K
V
H
R
A
I
A
Y
S
-
Y
E
Q
M
G
S
H
E
E
A
L
P
H
F
K
K
A
N
E
L
D
E
R
-------------------------------------------------------------------------------
10
PsiBlast_PDB
69.15
22%
-89
- C1 -
4UI9
-
CDC27_HUMAN
F:
[568-738]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
W
C
A
A
G
N
C
F
S
L
Q
R
E
H
D
I
A
I
K
F
F
Q
R
A
I
Q
V
D
P
N
Y
A
Y
-
A
Y
T
L
L
G
H
E
F
V
L
T
E
E
L
D
K
A
L
A
C
F
R
N
A
I
R
V
N
P
R
--
H
Y
N
A
W
Y
G
L
G
M
I
Y
Y
K
Q
E
K
F
S
L
A
E
M
H
F
Q
K
A
L
D
I
N
P
--------
Q
S
---------
S
V
L
L
C
H
I
-
G
V
V
Q
H
A
L
K
K
S
E
K
A
L
D
T
L
N
K
A
I
V
I
D
-------
P
K
N
P
L
C
K
F
H
R
A
S
V
L
F
-
A
N
E
K
Y
K
S
A
L
Q
E
L
E
E
L
K
Q
I
V
P
K
E
S
L
----------------------------------------------------------------------------
43
HHSearch
68.88
19%
-90
- C1 -
2XPI
1
CUT9_SCHPO
A:
[377-592]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
V
G
I
Y
Y
L
C
V
N
K
I
S
E
A
R
R
Y
F
S
K
S
S
T
M
D
P
Q
F
G
P
A
W
I
G
F
A
H
S
F
A
I
E
G
E
H
D
Q
A
I
S
A
Y
T
T
A
A
R
L
F
Q
G
T
H
L
-
P
Y
L
F
L
G
M
Q
H
M
Q
L
G
N
I
L
L
A
N
E
Y
L
Q
S
S
Y
A
L
F
Q
Y
--
D
P
L
L
L
N
E
L
G
V
V
A
F
N
K
S
D
M
Q
T
A
I
N
H
F
Q
N
A
L
L
L
V
K
K
T
QSNE
K
-
P
W
---------
A
A
T
W
A
N
L
-
G
H
A
Y
R
K
L
K
M
Y
D
A
A
I
D
A
L
N
Q
G
L
L
L
S
-------
T
N
D
A
N
V
H
T
A
I
A
L
V
-
Y
L
H
K
K
I
P
G
L
A
I
T
H
L
H
E
S
L
A
I
S
P
N
E
I
M
A
S
D
L
L
K
R
---------------------------------------------------------------------
14
PsiBlast_PDB
68.21
24%
-93
- C1 -
3AS4
6
?
A:
[11-174]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
R
D
K
G
I
S
H
A
K
A
G
R
Y
S
Q
A
V
M
L
L
E
Q
V
Y
D
A
D
A
F
D
V
D
-
V
A
L
H
L
G
I
A
Y
V
K
T
G
A
V
D
R
G
T
E
L
L
E
R
S
L
A
D
A
P
D
--
N
V
K
V
A
T
V
L
G
L
T
Y
V
Q
V
Q
K
Y
D
L
A
V
P
L
L
I
K
V
A
E
A
N
P
--------
I
N
---------
F
N
V
R
F
R
L
-
G
V
A
L
D
N
L
G
R
F
D
E
A
I
D
S
F
K
I
A
L
G
L
R
-------
P
N
E
G
K
V
H
R
A
I
A
F
S
-
Y
E
Q
M
G
R
H
E
E
A
L
P
H
F
K
K
A
N
E
L
D
---------------------------------------------------------------------------------
50
HHSearch
67.28
19%
-77
- C1 -
1FCH
2
PEX5_HUMAN
A:
[101-323]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
Q
Y
L
G
T
T
Q
A
E
N
E
Q
E
L
L
A
I
S
A
L
R
R
C
L
E
L
K
P
D
N
Q
T
A
L
M
A
L
A
V
S
F
T
N
E
S
L
Q
R
Q
A
C
E
I
L
R
D
W
L
R
Y
T
P
A
Y
A
H
-
L
V
T
R
I
L
G
S
L
L
S
D
S
L
F
L
E
V
K
E
L
F
L
A
A
V
R
L
D
P
T
SI
D
P
D
V
Q
C
G
L
G
V
L
F
N
L
S
G
E
Y
D
K
A
V
D
C
F
T
A
A
L
S
V
R
P
--------
N
D
---------
Y
L
L
W
N
K
L
-
G
A
T
L
A
N
G
N
Q
S
E
E
A
V
A
A
Y
R
R
A
L
E
L
Q
-------
P
G
Y
I
R
S
R
Y
N
L
G
I
S
-
C
I
N
L
G
A
H
R
E
A
V
E
H
F
L
E
A
L
N
M
Q
R
K
-------------------------------------------------------------------------------
54
Fugue
67.15
16%
-74
- C1 -
3LCA
3
TOM71_YEAST
A:
[18-531]
---------------------------------------------------------------------Q
A
Y
A
V
Q
L
K
N
R
G
N
H
F
F
T
A
KN
F
N
E
A
I
K
Y
Y
Q
Y
A
I
E
L
DPNE
P
V
F
Y
S
N
I
S
A
C
Y
I
S
T
GD
L
E
K
V
I
E
F
T
T
K
A
L
E
I
KPDH
S
K
A
L
L
R
R
A
S
A
N
E
S
L
GN
F
T
D
A
M
F
D
L
S
V
L
S
L
NI
E
P
M
L
E
R
N
L
N
K
Q
A
M
K
V
L
N
E
N
L
SQVLPS
N
T
S
L
A
S
F
F
GIFD
S
H
L
E
V
S
SVNTSSNYDTA
Y
A
L
L
S
D
A
L
Q
R
L
Y
SAT
D
E
G
Y
L
V
A
N
D
L
L
T
K
S
T
D
M
Y
H
S
LP
L
R
E
N
A
A
L
A
L
C
Y
T
G
I
F
H
F
L
K
NN
L
L
D
A
Q
V
L
L
Q
E
S
I
N
L
H
P
T
P
N
S
Y
I
F
L
A
L
T
L
A
S
Q
E
F
F
K
F
F
Q
K
A
V
D
L
N
P
E
Y
P
P
T
Y
Y
H
R
G
Q
M
Y
F
I
L
Q
D
Y
K
N
A
K
E
D
F
Q
K
A
Q
S
L
N
P
E
N
V
Y
-
P
Y
I
Q
L
A
C
L
L
Y
K
Q
G
K
F
T
E
S
E
A
F
F
N
E
T
K
L
K
F
P
T
--
L
P
E
V
P
T
F
F
A
E
I
L
T
D
R
G
D
F
D
T
A
I
K
Q
Y
D
I
A
K
R
L
E
E
------
V
-
Q
E
KIHVGI
G
P
L
I
G
K
A
T
I
L
-
A
R
Q
S
L
D
E
E
K
F
N
A
A
I
K
L
L
T
K
A
C
E
L
D
-------
P
R
S
E
Q
A
K
I
G
L
A
Q
L
K
L
Q
M
E
-
K
I
D
E
A
I
E
L
F
E
D
S
A
I
L
A
R
T
M
D
E
K
L
Q
A
T
T
F
A
E
A
A
K
I
Q
K
R
L
R
A
D
P
I
I
S
A
K
M
E
L
T
L
A
R
Y
R
A
K
G--------------------------------------
21
PsiBlast_CBE
66.38
34%
-94
- C1 -
1NA0
8
?
B:
[7-120]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
S
A
E
A
W
Y
N
L
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
P
N
--
N
A
E
A
W
Y
N
L
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
P
------
N
--
N
---------
A
E
A
W
Y
N
L
-
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
-------
P
N
N
A
E
A
K
Q
N
L
G
N
A
-------------------------------------------------------------------------------------------------------
46
HHSearch
66.37
23%
-84
- C1 -
1W3B
-
OGT1_HUMAN
A:
[3-205]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
L
A
H
R
E
Y
Q
A
G
D
F
E
A
A
E
R
H
C
M
Q
L
W
R
Q
E
P
D
N
T
G
V
L
L
L
L
S
S
I
H
F
Q
C
R
R
L
D
R
S
A
H
F
S
T
L
A
I
K
Q
N
P
L
L
A
E
-
A
Y
S
N
L
G
N
V
Y
K
E
R
G
Q
L
Q
E
A
I
E
H
Y
R
H
A
L
R
L
K
P
D
--
F
I
D
G
Y
I
N
L
A
A
A
L
V
A
A
G
D
M
E
G
A
V
Q
A
Y
V
S
A
L
Q
Y
N
P
--------
D
L
---------
Y
C
V
R
S
D
L
-
G
N
L
L
K
A
L
G
R
L
E
E
A
K
A
C
Y
L
K
A
I
E
T
Q
-------
P
N
F
A
V
A
W
S
N
L
G
C
V
-
F
N
A
Q
G
E
I
W
L
A
I
H
H
F
E
K
A
V
T
L
D
P
N
F
L
D
A
---------------------------------------------------------------------------
53
Fugue
66.08
17%
-67
- C1 -
1FCH
2
PEX5_HUMAN
A:
[46-368]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SATYDKGYQFEEENPLRDH
P
Q
P
F
E
E
G
L
R
R
L
Q
E
G
D
L
P
N
A
V
L
L
F
E
A
A
V
Q
Q
D
P
K
H
M
E
A
W
Q
Y
L
G
T
T
Q
A
E
N
E
Q
E
L
L
A
I
S
A
L
R
R
C
L
E
L
K
P
D
N
Q
T
-
A
L
M
A
L
A
V
S
F
T
N
E
S
L
Q
R
Q
A
C
E
I
L
R
D
W
L
R
Y
T
P
A
--
Y
A
H
L
V
T
R
I
L
G
S
L
L
S
D
S
L
F
L
E
V
K
E
L
F
L
A
A
V
R
L
D
P
------
T
S
I
D
---------
P
D
V
Q
C
G
L
-
G
V
L
F
N
L
S
G
E
Y
D
K
A
V
D
C
F
T
A
A
L
S
V
R
-------
P
N
D
Y
L
L
W
N
K
L
G
A
T
L
A
N
G
N
Q
-
S
E
E
A
V
A
A
Y
R
R
A
L
E
L
Q
P
G
Y
I
R
S
R
Y
N
L
G
I
S
C
I
N
L
G
A
H
R
E
A
V
E
H
F
L
E
A
L
N
M
Q
R
K
SGGAMS
E
N
I
W
S
T
L
R
L
A
L
S
M
L
GQSDA
Y
G
A
A
D
A
RD
L
S
T
L
L
T
M
F
GLPQ
3
PsiBlast_PDB
63.76
34%
-91
- C1 -
2HYZ
3
?
A:
[3-135]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
W
Y
N
L
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
P
R
--
S
A
E
A
W
Y
N
L
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
P
--------
R
S
---------
A
E
A
W
Y
N
L
-
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
-------
P
R
S
A
E
A
W
Y
N
L
G
N
A
-
Y
Y
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
P
R
-------------------------------------------------------------------------------
16
PsiBlast_PDB
62.72
24%
-81
- C1 -
4RG6
-
CDC27_HUMAN
A:
[299-474]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
N
S
P
E
A
W
C
A
A
G
N
C
F
S
L
Q
R
E
H
D
I
A
I
K
F
F
Q
R
A
I
Q
V
D
P
N
Y
A
Y
-
A
Y
T
L
L
G
H
E
F
V
L
T
E
E
L
D
K
A
L
A
C
F
R
N
A
I
R
V
N
P
R
--
H
Y
N
A
W
Y
G
L
G
M
I
Y
Y
K
Q
E
K
F
S
L
A
E
M
H
F
Q
K
A
--
L
D
I
------
N
-
P
Q
---------
S
S
V
L
L
C
H
I
G
V
V
Q
H
A
L
--------
T
L
N
K
A
I
V
I
D
-------
P
K
N
P
L
C
K
F
H
R
A
S
V
L
F
A
-
N
E
K
Y
K
S
A
L
Q
E
L
E
E
L
K
Q
I
V
P
K
E
S
L
----------------------------------------------------------------------------