@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1522: (2016-03-26 )
MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDVEQQALAIKSAFVAQLDSLESLSRDEIANDRFEKFRNIGSYIE
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20........30........40........50........60......-..70......--..80........90........100.......110....------------.--..------120........130.......140.......150.......160....---...170.......180.......190...--.--...200.---..------.----.--..----210.-.--.....220.......230.....-----.------------.-----------240----.-----.---------------.------......250.......260.......270.......280.......290.......300.......310..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLDF
E
K
P
L
F
E
I
R
N
K
I
E
S
L
K
ESQDKND
V
D
L
Q
E
E
I
D
M
L
E
A
S
L
E
R
E
T
K
K
I
YTNLKP
W
D
R
V
Q
I
A
R
L
QERPT-TL
D
Y
I
P
Y
I
F
D
--
S
F
M
E
L
HGDRNFRDDP
A
M
I
G
G
I
G
FLN
G
R
A
V
T
V
I
GQQRGKD------------
T
--
K
D
------
N
I
-
Y
R
NFGMAH
P
E
G
Y
R
K
A
L
R
L
M
K
Q
A
E
K
FNR
P
I
F
T
F
IDTKGAYPG
K
A
A
E
---ERGQ
S
E
S
I
A
T
N
L
I
E
M
ASLKV
P
V
I
A
I
V
I
GE--G--GSGG
A
L
G
---
I
G------I----A--
N
K
----
V
L
M
L
-E--NS
T
Y
S
V
ISPEG
A
A
A
L
L
WKDS
N
L
A
-----
K
------------
I
-----------
A
------
A
-----
E
---------------
T
------
M
K
I
T
A
H
D
I
K
Q
LG
I
I
D
D
V
I
SEPLGGA
H
K
D
V
E
Q
Q
A
L
A
I
K
S
A
F
V
A
Q
L
D
S
L
E
S
L
S
R
D
E
I
A
N
D
R
F
E
K
F
R
N
I
GSYIE
42
Fugue
96.74
99%
-78
- C2 -
2F9I
-
ACCA_STAA3 (first)
A:
[8-327]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVPRGS
M
L
D
F
E
K
P
L
F
E
I
R
N
K
I
E
-----------
S
L
Q
E
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M
L
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A
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N
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W
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-
T
L
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Y
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--
S
F
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N
F
R
D
D
P
A
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I
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N
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A
V
T
V
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G
Q
Q
R
G
K
D
------------
T
--
K
D
------
N
I
-
Y
R
N
F
G
M
A
H
P
E
G
Y
R
K
A
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L
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N
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F
T
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A
Y
P
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K
A
A
E
---
E
R
G
Q
S
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S
I
A
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N
L
I
E
M
A
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V
P
V
I
A
I
V
I
G
E
--
G
--
G
S
G
G
A
L
G
---
I
G
------
I
----
A
--
N
K
----
V
L
M
L
-
E
--
N
S
T
Y
S
V
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G
A
A
A
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L
W
K
D
S
N
L
A
-----
K
------------
I
-----------
A
------
A
-----
E
---------------
T
------
M
K
I
T
A
H
D
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L
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A
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A
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A
Q
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L
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S
L
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I
A
N
D
R
F
E
K
F
R
N
I
G
S
Y
I
E
21
HHSearch
96.19
100%
-79
- C2 -
2F9I
-
ACCA_STAA3 (first)
A:
[14-327]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
D
F
E
K
P
L
F
E
I
R
N
K
I
E
S
L
-----------
Q
E
E
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D
M
L
E
A
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I
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L
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R
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Q
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T
-
T
L
D
Y
I
P
Y
I
F
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--
S
F
M
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L
H
G
D
R
N
F
R
D
D
P
A
M
I
G
G
I
G
F
L
N
G
R
A
V
T
V
I
G
Q
Q
R
G
K
D
------------
T
--
K
D
------
N
I
-
Y
R
N
F
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M
A
H
P
E
G
Y
R
K
A
L
R
L
M
K
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N
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F
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F
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G
A
Y
P
G
K
A
A
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---
E
R
G
Q
S
E
S
I
A
T
N
L
I
E
M
A
S
L
K
V
P
V
I
A
I
V
I
G
E
--
G
--
G
S
G
G
A
L
G
---
I
G
------
I
----
A
--
N
K
----
V
L
M
L
-
E
--
N
S
T
Y
S
V
I
S
P
E
G
A
A
A
L
L
W
K
D
S
N
L
A
-----
K
------------
I
-----------
A
------
A
-----
E
---------------
T
------
M
K
I
T
A
H
D
I
K
Q
L
G
I
I
D
D
V
I
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E
P
L
G
G
A
H
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E
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Q
A
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A
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K
S
A
F
V
A
Q
L
D
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L
E
S
L
S
R
D
E
I
A
N
D
R
F
E
K
F
R
N
I
G
S
Y
I
E
1
PsiBlast_PDB
95.98
99%
-79
- C2 -
2F9I
-
ACCA_STAA3 (first)
A:
[14-327]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
D
F
E
K
P
L
F
E
I
R
N
K
I
E
S
L
-----------
Q
E
E
I
D
M
L
E
A
S
L
E
R
E
T
K
K
I
Y
T
N
L
K
P
W
D
R
V
Q
I
A
R
L
Q
E
R
P
T
-
T
L
D
Y
I
P
Y
I
F
D
--
S
F
M
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G
D
R
N
F
R
D
D
P
A
M
I
G
G
I
G
F
L
N
G
R
A
V
T
V
I
G
Q
Q
R
G
K
D
------------
T
--
K
D
------
N
I
-
Y
R
N
F
G
M
A
H
P
E
G
Y
R
K
A
L
R
L
M
K
Q
A
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K
F
N
R
P
I
F
T
F
I
D
T
K
G
A
Y
P
G
K
A
A
E
---
E
R
G
Q
S
E
S
I
A
T
N
L
I
E
M
A
S
L
K
V
P
V
I
A
I
V
I
G
E
--
G
--
G
S
G
G
A
L
G
---
I
G
------
I
----
A
--
N
K
----
V
L
M
L
-
E
--
N
S
T
Y
S
V
I
S
P
E
G
A
A
A
L
L
W
K
D
S
N
L
A
-----
K
------------
I
-----------
A
------
A
-----
E
---------------
T
------
M
K
I
T
A
H
D
I
K
Q
L
G
I
I
D
D
V
I
S
E
P
L
G
G
A
H
K
D
I
E
Q
Q
A
L
A
I
K
S
A
F
V
A
Q
L
D
S
L
E
S
L
S
R
D
E
I
A
N
D
R
F
E
K
F
R
N
I
G
S
Y
I
E
2
PsiBlast_PDB
78.04
52%
-60
- C2 -
2F9Y
-
ACCA_ECOLI
A:
[26-337]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
F
E
Q
P
I
A
E
L
E
A
K
I
D
S
------------
D
E
E
V
H
R
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L
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I
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A
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L
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A
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A
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A
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T
L
D
Y
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A
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D
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F
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A
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A
Y
A
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D
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A
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V
G
G
I
A
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D
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R
P
V
M
I
I
G
H
Q
K
G
R
E
------------
T
--
K
E
------
K
I
-
R
R
N
F
G
M
P
A
P
E
G
Y
R
K
A
L
R
L
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Q
M
A
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M
P
I
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T
P
G
A
Y
P
G
V
G
A
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---
E
R
G
Q
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A
I
A
R
N
L
R
E
M
S
R
L
G
V
P
V
V
C
T
V
I
G
E
--
G
--
G
S
G
G
A
L
A
---
I
G
------
V
----
G
--
D
K
----
V
N
M
L
-
Q
--
Y
S
T
Y
S
V
I
S
P
E
G
C
A
S
I
L
W
K
S
A
D
K
A
-----
P
------------
L
-----------
A
------
A
-----
E
---------------
A
------
M
G
I
I
R
P
R
L
K
E
L
K
L
I
D
S
I
I
P
E
P
L
G
G
A
H
R
N
P
E
A
M
A
A
S
L
K
A
Q
L
L
A
D
L
A
D
L
D
V
L
S
T
E
D
L
K
N
R
R
Y
Q
R
L
M
S
Y
G
----
22
HHSearch
77.98
52%
-60
- C2 -
2F9Y
-
ACCA_ECOLI
A:
[25-339]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
L
D
F
E
Q
P
I
A
E
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E
A
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E
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V
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-
T
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Y
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A
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--
E
F
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E
L
A
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A
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A
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A
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R
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------------
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--
K
E
------
K
I
-
R
R
N
F
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M
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A
P
E
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Y
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M
A
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A
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P
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E
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--
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S
G
G
A
L
A
---
I
G
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G
--
D
K
----
V
N
M
L
-
Q
--
Y
S
T
Y
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V
I
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E
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C
A
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W
K
S
A
D
K
A
-----
P
------------
L
-----------
A
------
A
-----
E
---------------
A
------
M
G
I
I
R
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R
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E
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L
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G
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L
L
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A
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Y
Q
R
L
M
S
Y
G
Y
A
--
33
HHSearch
60.56
23%
-75
- C2 -
1X0U
-
?
A:
[285-511]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
A
K
P
Y
N
-
M
R
E
I
I
Y
K
I
V
D
NG
E
F
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E
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--
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--
Q
N
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I
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F
A
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I
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A
N
N
P
E
-----------------------------
E
F
G
G
S
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A
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---
Y
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L
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A
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A
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--
S
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G
G
A
H
I
A
---
M
S
IKSL--
G
----
A
--
D
L
----
V
Y
A
W
-
P
--
T
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E
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A
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P
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A
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-----
A
SNPDDVL
K
----
Q
-----------
R
------
I
A
E
Y
--
R
---------------
K
------
L
F
A
N
P
Y
W
A
A
E
K
G
L
V
D
D
V
I
---------
E
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----
T
R
R
V
I
V
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G
L
E
M
L
K
T
K
R
E
-------------------
27
HHSearch
58.25
26%
-82
- C2 -
1VRG
1
?
A:
[291-514]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
G
Y
D
-
V
R
D
V
I
K
R
V
V
D
HG
E
F
F
E
V
Q
P
Y
--
F
A
--
K
N
I
V
I
G
F
A
R
I
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I
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A
N
Q
P
S
-----------------------------
V
L
A
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L
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---
H
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E
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--
A
--
Y
G
G
A
Y
I
A
---
M
G
SKHL--
G
----
A
--
D
M
----
V
L
A
W
-
P
--
S
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A
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A
-----
S
------------
S
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P
E
E
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---
L
------
I
-----
E
E
Y
K
------------
Q
------
Q
F
A
N
P
Y
I
A
A
S
R
G
Y
V
D
M
V
I
---------
D
P
R
E
----
T
R
K
Y
I
M
R
A
L
E
V
C
E
T
K
V
--------------------
37
HHSearch
57.98
23%
-84
- C2 -
3IAV
3
?
A:
[291-518]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
N
Q
P
Y
D
M
H
S
V
I
E
H
V
L
D
DA
E
F
F
E
T
Q
P
L
--
F
A
--
P
N
I
L
T
G
F
G
R
V
E
G
R
P
V
G
I
V
A
N
Q
P
M
-----------------------------
Q
F
A
G
C
L
D
I
T
A
S
E
K
A
A
R
F
V
R
T
C
D
A
F
N
V
P
V
L
T
F
V
D
V
P
G
F
L
P
G
V
D
Q
E
---
H
D
G
I
I
R
R
G
A
K
L
I
F
A
Y
A
E
A
T
V
P
L
I
T
V
I
T
R
K
--
A
--
F
G
G
A
Y
V
V
---
M
G
SKHL--
G
----
A
--
D
L
----
N
L
A
W
-
P
--
T
A
Q
I
A
V
M
G
A
Q
G
A
V
N
I
L
H
R
R
T
I
A
D
-----
A
GDDA
E
A
T
R
A
---
R
-----------
L
------
I
Q
E
Y
--
E
---------------
D
------
A
L
L
N
P
Y
T
A
A
E
R
G
Y
V
D
A
V
I
---------
M
P
S
D
----
T
R
R
H
I
V
R
G
L
R
Q
L
R
T
K
R
E
-------------------
31
HHSearch
57.60
18%
-76
- C2 -
1PIX
3
GCDA_ACIFV
A:
[318-565]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
A
Y
D
-
I
Y
N
V
I
A
R
L
F
D
NS
E
L
H
E
Y
K
K
G
--
Y
G
--
P
E
M
V
T
G
L
A
K
V
N
G
L
L
V
G
V
V
A
N
V
Q
G
L
L
------------
M
--
N
Y
PEYKAA
G
S
-
V
G
I
G
G
K
L
Y
R
Q
G
L
V
K
M
N
E
F
V
T
L
C
A
R
D
R
L
P
I
V
W
I
Q
D
T
T
G
I
D
V
G
N
D
A
E
---
K
A
E
L
L
G
L
G
Q
S
L
I
Y
S
I
Q
T
S
H
I
P
Q
F
E
I
T
L
R
K
--
G
--
T
A
A
A
H
Y
V
---
L
G
GPQGND
T
----
N
--
A
F
----
S
I
G
T
-
A
--
A
T
E
I
A
V
M
N
G
E
T
A
A
T
A
M
Y
S
R
R
L
A
K
-----
D
------------
R
K
A
GKDL
Q
P
T
I
D
K
------
M
-----
N
---------------
N
L
I
Q
A
F
Y
T
K
S
R
P
K
V
C
A
E
L
G
L
V
D
E
I
V
---------
D
M
N
K
----
I
R
G
Y
V
E
A
F
T
E
A
A
Y
Q
N
P
E
S
------------------
30
HHSearch
57.40
22%
-77
- C2 -
1ON3
3
12S_PROFR
A:
[286-509]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
K
G
Y
D
-
V
R
D
V
I
A
K
I
V
D
WG
D
Y
L
E
V
K
A
G
--
Y
A
--
T
N
L
V
T
A
F
A
R
V
N
G
R
S
V
G
I
V
A
N
Q
P
S
-----------------------------
V
M
S
G
C
L
D
I
N
A
S
D
K
A
A
E
F
V
N
F
C
D
S
F
N
I
P
L
V
Q
L
V
D
V
P
G
F
L
P
G
V
Q
Q
E
---
Y
G
G
I
I
R
H
G
A
K
M
L
Y
A
Y
S
E
A
T
V
P
K
I
T
V
V
L
R
K
--
A
--
Y
G
G
S
Y
L
A
---
M
C
NRDL--
G
----
A
--
D
A
----
V
Y
A
W
-
P
--
S
A
E
I
A
V
M
G
A
E
G
A
A
N
V
I
F
R
K
E
I
K
A
-----
A
------------
D
-----------
D
------
P
-----
D
A
M
R
A
E
K
I
E
E
Y
Q
----
N
------
A
F
N
T
P
Y
V
A
A
A
R
G
Q
V
D
D
V
I
---------
D
P
A
D
----
T
R
R
K
I
A
S
A
L
E
M
Y
A
T
K
---------------------
26
HHSearch
56.65
22%
-80
- C2 -
3N6R
1
?
B:
[297-519]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
P
N
T
P
Y
D
M
K
E
L
I
H
K
L
A
D
EG
D
F
Y
E
I
Q
E
E
--
F
A
--
K
N
I
I
T
G
F
I
R
L
E
G
R
T
V
G
V
V
A
N
Q
P
L
-----------------------------
V
L
A
G
C
L
D
I
D
S
S
R
K
A
A
R
F
V
R
F
C
D
A
F
E
I
P
L
L
T
L
I
D
V
P
G
F
L
P
G
T
S
Q
E
---
Y
G
G
V
I
K
H
G
A
K
L
L
Y
A
Y
G
E
A
T
V
P
M
V
T
V
I
T
R
K
--
A
--
Y
G
G
A
Y
V
V
---
M
S
SKHL--
R
----
A
--
D
F
----
N
Y
A
W
-
P
--
T
A
E
V
A
V
M
G
A
K
G
A
T
E
I
I
H
R
G
D
L
G
D
-----
P
------------
E
K
I
A
Q
-------
H
------
T
-----
A
---------------
D
Y
E
E
---
R
F
A
N
P
F
V
A
S
E
R
G
F
V
D
E
V
I
---------
Q
P
R
S
----
T
R
K
R
V
A
R
A
F
A
S
L
R
N
K
S
V
-------------------
25
HHSearch
56.49
19%
-86
- C2 -
3U9R
2
?
B:
[315-545]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
S
K
Q
P
Y
D
-
V
R
E
V
I
A
R
L
V
D
GS
E
F
D
E
F
K
A
L
--
F
G
--
T
T
L
V
C
G
F
A
H
L
H
G
Y
P
I
A
I
L
A
N
N
----------------------------------
G
I
L
F
A
E
A
A
Q
K
G
A
H
F
I
E
L
A
C
Q
R
G
I
P
L
L
F
L
Q
N
I
T
G
F
M
V
G
Q
K
Y
E
---
A
G
G
I
A
K
H
G
A
K
L
V
T
A
V
A
C
A
R
V
P
K
F
T
V
L
I
G
G
--
S
--
F
G
A
G
N
Y
G
---
M
C
------
G
RAYD
P
--
R
F
----
L
W
M
W
-
P
--
N
A
R
I
G
V
M
G
G
E
Q
A
A
G
V
L
A
Q
V
K
R
E
Q
-----
A
ERAGQQLGVEEE
A
-----------
K
------
I
K----
A
---------------
P
ILEQYE
H
Q
G
H
P
Y
Y
S
S
A
R
L
W
D
D
G
V
I
---------
D
P
A
Q
----
T
R
E
V
L
A
L
A
L
S
A
A
L
N
A
P
I
-------------------
43
Fugue
54.72
17%
-52
- C2 -
1ON3
5
12S_PROFR
A:
[7-523]
KLAST
M
E
G
R
V
E
Q
L
A
E
Q
R
Q
V
I
E
A
GGG
E
R
R
V
E
K
Q
H
S
Q
GKQT
A
R
E
R
L
N
N
L
L
DPHS
F
D
E
V
GAFRKHRTTLFGMDK
A
V
V
P
ADG
V
V
T
G
R
G
T
I
LG
R
P
V
H
A
A
S
Q
D
FTVMGGSAG
E
T
Q
S
T
K
V
V
E
T
M
E
Q
A
L
L
T
G
T
P
F
L
F
F
Y
D
SGGARIQE
G
I
D
S
L
S
G
Y
G
K
M
F
F
A
N
V
K
L
SGV
V
P
Q
I
A
I
I
AGPCAGG
A
S
Y
S
P
A
L
TD
F
I
I
M
T
KK
A
H
M
F
ITG
P
Q
V
I
K
S
V
TG
E
D
V
T
ADELGG
A
E
A
H
M
AISGNIHFV
A
E
D
D
D
A
A
E
L
I
A
K
K
L
L
S
F
L
P
Q
N
N
T
-------
E
E
A
S
F
V
N
P
N
N
D
V
S
P
N
T
E
L
R
D
I
V
P
I
D
G
------
K
K
G
Y
D
-
V
R
D
V
I
A
K
I
V
D
WG
D
Y
L
E
V
K
A
G
Y
A
----
T
N
L
V
T
A
F
A
R
V
N
G
R
S
V
G
I
V
A
N
Q
----------------------------
P
-
S
V
M
S
G
C
L
D
I
N
A
S
D
K
A
A
E
F
V
N
F
C
D
S
F
N
I
P
L
V
Q
L
V
D
V
P
G
F
L
P
G
V
Q
Q
E
---
Y
G
G
I
I
R
H
G
A
K
M
L
Y
A
Y
S
E
A
T
V
P
K
I
T
V
V
L
R
K
--
A
--
Y
G
G
S
Y
L
A
---
M
C
------
N
----
R
--
D
L
GAD
A
V
Y
A
W
-
P
--
S
A
E
I
A
V
M
G
A
E
G
A
A
N
V
I
F
R
K
E
I
K
A
-----
A
------------
D
-----------
D
------
P
-----
D
---------------
A
------
M
R
A
E
K
I
E
E
Y
Q
N
A
F
N
T
P
Y
V
A
A
A
R
G
Q
V
D
D
V
I
D
--
P
A
D
T
R
R
K
I
A
S
A
L
E
M
Y
A
T
K
R
Q
T
R
P
A
K
K
H
G
N
F
P
C
-------
41
HHSearch
53.56
19%
-78
- C2 -
2X24
1
?
A:
[392-681]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-
K
G
S
W
Q
S
G
F
F
D
QG
S
F
K
E
I
M
V
P
--
W
A
--
Q
T
V
V
T
G
R
A
R
L
G
G
I
P
V
G
V
I
A
A
E
T
R
T
V
E
L
V
V
P
A
D
PANLD
S
--
E
A
------
K
I
I
Q
Q
A
G
Q
V
W
F
P
D
S
A
Y
K
T
A
Q
A
I
K
D
F
N
R
E
K
L
P
L
M
I
F
A
N
W
R
G
F
S
G
G
M
K
D
M
---
Y
D
Q
V
L
K
F
G
A
Y
I
V
D
G
L
R
K
Y
R
Q
P
V
L
I
Y
I
P
P
Y
--
A
E
V
R
G
G
S
W
A
V
---
M
D
TSI---
N
----
P
L
C
I
E
----
M
Y
A
D
-
R
--
E
S
R
A
S
V
L
E
P
E
G
T
V
E
I
K
Y
Q
K
K
D
L
V
K
T
I
R
R
L
DPISK---------------------------Q
L
K
A
R
E
D
L
L
L
P
M
Y
H
Q
V
A
L
H
F
A
D
------
L
H
D
T
A
G
R
M
L
E
K
G
V
I
Y
D
I
L
---------
E
W
K
T
----
A
R
S
F
L
Y
W
R
L
R
R
L
------------------------
29
HHSearch
53.38
21%
-61
- C2 -
3GF3
1
?
A:
[318-570]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
Q
K
R
P
Y
D
I
Y
E
V
I
A
R
L
F
D
NS
E
F
S
E
Y
K
K
G
--
Y
G
--
P
E
M
V
T
G
L
A
K
V
N
G
L
L
V
G
V
I
A
N
V
Q
G
L
L
------------
M
NY
P
E
YKQ---
N
S
-
V
G
I
G
G
K
L
Y
R
Q
G
L
I
K
M
N
E
F
V
T
L
C
A
R
D
R
I
P
L
I
W
L
Q
D
T
T
G
I
D
V
G
D
E
A
E
---
K
A
E
L
L
G
L
G
Q
S
L
I
Y
S
I
E
N
S
K
L
P
S
L
E
I
T
I
R
K
--
A
--
S
A
A
A
H
Y
V
---
L
G
GPQG--
N
----
N
--
T
N
----
V
F
S
I
-
G
T
G
A
C
E
Y
Y
V
M
P
G
E
T
A
A
N
A
M
Y
S
R
K
L
V
K
-----
A
-------------------------Q
P
I
I
G
K
M
N
D
M
I
-
Q
M
Y
-------------
T
------
D
K
S
R
P
K
Y
C
T
E
K
G
M
V
D
E
I
V
---------
D
M
T
E
----
V
R
P
Y
I
Q
A
F
T
E
A
A
Y
Q
N
-
P
Q
S
I
C
P
--------------
19
PsiBlast_PDB
52.96
23%
-60
- C2 -
3U9R
1
?
B:
[111-287]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
V
A
G
I
G
R
V
E
G
V
E
C
M
I
V
G
N
D
--
A
T
------------
V
--
K
G
------
G
T
-
Y
------
Y
P
L
T
V
K
K
H
L
R
A
Q
A
I
A
L
E
N
R
L
P
C
I
Y
L
V
D
S
G
G
A
N
L
P
R
Q
D
E
VFP
D
R
E
H
F
G
R
I
F
F
N
Q
A
N
M
S
A
R
G
I
P
Q
I
A
V
V
M
G
S
--
C
--
T
A
G
G
A
Y
V
---
P
A
------
M
----
S
--
D
E
----
T
V
M
V
R
E
--
Q
A
T
I
F
L
A
G
P
P
-----
L
V
K
A
A
T
G
E
-----
V
------------
V
-----------
S
------
A
-----
E
---------------
E
------
L
G
G
A
D
V
H
C
K
V
S
G
V
A
D
H
---------
Y
A
E
D
D
D
H
A
L
A
I
A
R
R
C
V
A
N
L
N
--------------------------
20
PsiBlast_PDB
51.79
23%
-62
- C2 -
3U9S
1
?
B:
[111-287]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
V
A
G
I
G
R
V
E
G
V
E
C
M
I
V
G
N
D
--
A
T
------------
V
--
K
G
------
G
T
-
Y
------
Y
P
L
T
V
K
K
H
L
R
A
Q
A
I
A
L
E
N
R
L
P
C
I
Y
L
V
D
S
G
G
A
N
L
P
R
Q
D
E
VFP
D
R
E
H
F
G
R
I
F
F
N
Q
A
N
M
S
A
R
G
I
P
Q
I
A
V
V
M
G
S
--
C
--
T
A
G
G
A
Y
V
---
P
A
------
M
----
S
--
D
E
----
T
V
M
V
R
E
--
Q
A
T
I
F
L
A
G
P
P
-----
L
V
K
A
A
T
G
E
-----
V
------------
V
-----------
S
------
A
-----
E
---------------
E
------
L
G
G
A
D
V
H
C
K
V
S
G
V
A
D
H
---------
Y
A
E
D
D
D
H
A
L
A
I
A
R
R
C
V
A
N
L
N
--------------------------
11
PsiBlast_PDB
51.46
25%
-71
- C2 -
1XNV
-
?
A:
[320-456]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
N
I
L
T
G
F
G
R
V
E
G
R
P
V
G
I
V
A
N
Q
P
-----------------------------
M
Q
F
A
G
C
L
D
I
T
A
S
E
K
A
A
R
F
V
R
T
C
D
A
F
N
V
P
V
L
T
F
V
D
V
P
G
F
L
P
G
V
D
Q
E
---
H
D
G
I
I
R
R
G
A
K
L
I
F
A
Y
A
E
A
T
V
P
L
I
T
V
I
T
R
K
AF
G
--
G
A
Y
D
V
M
G
SKH
L
G
-----------
A
--
D
L
----
N
L
A
W
-
P
--
T
A
Q
I
A
V
M
G
A
Q
G
A
V
N
I
L
H
R
----------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
51.13
25%
-68
- C2 -
1XNY
2
?
A:
[320-456]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
N
I
L
T
G
F
G
R
V
E
G
R
P
V
G
I
V
A
N
Q
P
-----------------------------
M
Q
F
A
G
C
L
D
I
T
A
S
E
K
A
A
R
F
V
R
T
C
D
A
F
N
V
P
V
L
T
F
V
D
V
P
G
F
L
P
G
V
D
Q
E
---
H
D
G
I
I
R
R
G
A
K
L
I
F
A
Y
A
E
A
T
V
P
L
I
T
V
I
T
R
K
AF
G
--
G
A
Y
D
V
M
G
SKH
L
G
-----------
A
--
D
L
----
N
L
A
W
-
P
--
T
A
Q
I
A
V
M
G
A
Q
G
A
V
N
I
L
H
R
----------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
50.48
24%
-71
- C2 -
1XNW
-
?
A:
[320-456]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
N
I
L
T
G
F
G
R
V
E
G
R
P
V
G
I
V
A
N
Q
P
-----------------------------
M
Q
F
A
G
C
L
D
I
T
A
S
E
K
A
A
R
F
V
R
T
C
D
A
F
N
V
P
V
L
T
F
V
D
V
P
G
F
L
P
G
V
D
Q
E
---
H
D
G
I
I
R
R
G
A
K
L
I
F
A
Y
A
E
A
T
V
P
L
I
T
V
I
T
R
K
--
A
--
F
G
G
A
Y
I
V
---
M
G
------
S
KHLG
A
--
D
L
----
N
L
A
W
-
P
--
T
A
Q
I
A
V
M
G
A
Q
G
A
V
N
I
L
H
R
----------------------------------------------------------------------------------------------------------------------------------------------