@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1654: (2016-03-27 )
MHNQATTLFNKRLHALRKEKNYYNKFIFNGHFMVFLLILLGAFIFGYGEWLKHIPTNINFALIAAVIVALTSIFPMRPLLKEADKIFLLPFEKHMSQFMRHAILYSYFARILIQLIIVIVMFPLFYNINQHNVAFYICFGFSALIFPYVGLRLRWQWYQSGLKTWQVNLISFIIFALTYYLLLAPKWYIVFVMVALPVLIEFLVKKYKPGFLYPWEKMIAIEHRHHMNYYKFVNMFTDVKHLKESAVRRSYLDILLPVPKGSKFNSNAMYLFLFIRSFIRGRDAFNIIFRLVIIAVLLMVWLSYPLVTGVIGSLFVYIILLQMAQFYSQQAYGLWPQVWPVPEEKVIKGYEQFLYRLMFVICTVFAVTFIIKHMTLFYVVLIFYIVGLLTIRSIIKKLKYQETLLRD
Atome Classification :
(19 SA)
----------.........10........20........30-.........-40........50.....--...60........----------------------70...-----.....80........90........100------.-----........110.......120.......130.......140.......150....-...160.......170......--.180.....-..190....----...200..---------------------.....-----210.......220.......230.......240..---.....250.......260........270--...---......280.......290.......300..-----------------.....310.......320---------........330.......340.......350.-------......360..-------------------------.....370----.......380.......390.......400.....---------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------MHN
Q
A
T
T
L
F
N
K
R
L
H
A
L
R
K
EKN
Y
Y
N
K
F
IFN
G
--
H
F
M
V
F
L
L
I
L
-
L
G
A
F
I
F
G
Y
G
E
W
L
K
HIPT--NI
N
F
A
L
I
A
A
V
I
V
A
----------------------
L
T
SIF-----PM
R
P
L
L
K
EA
D
K
I
F
L
L
P
F
E
K
H
M
S
Q
F
M
R
--------
H
-----
A
I
L
Y
S
Y
F
A
R
I
L
I
Q
L
I
I
V
I
V
M
F
P
L
F
YNINQH
N
V
A
F
Y
I
C
F
G
F
S
A
L
I
F
P
YVG
L
R
L
R
W
Q
-
W
Y
QSGL
K
T
W
Q
V
N
L
I
S
F
I
I
F
A
L
T
--
Y
Y
L
L
LAP
K
W
-
Y
I
V
F
V
M
V
A
L
----
P
V
L
I
E
F
L
V
---------------------
K
KYKP-----GFLY
P
W
E
K
M
I
A
I
E
H
RHHM
N
Y
Y
K
F
V
N
M
F
T
D
V
K
H
L
K
E
---
S
A
V
R
R
S
Y
L
D
I
L
L
PVPK-GSKFNSN
A
M
Y
----
L
F
L
---
F
I
R
S
F
IRG
R
D
A
F
N
I
I
F
R
L
V
I
I
A
V
L
L
M
V
W
LS
Y
-----------------
P
L
V
T
G
V
I
G
S
L
F
V
Y
I
I
L
L
----------
Q
M
A
Q
F
Y
S
Q
Q
AYGLWPQVWPV
P
E
E
K
V
I
K
G
Y
E
Q
F
-------
L
Y
R
L
M
F
V
I
C
T
V
-------------------------
F
A
V
T
F
I
I
K
----
H
M
T
L
F
Y
V
V
L
I
F
Y
I
V
G
L
L
T
I
R
S
I
I
K
K
L
K
Y
Q
E
T
LLRD---------------
19
Fugue
89.34
18%
-147
- C6 -
4B3X
3
IF2_THET8
A:
[1-363]
-----------------
M
A
K
V
R
I
Y
Q
L
A
K
E
L
G
------
M
E
T
--
Q
E
L
L
E
L
L
D
Q
-
M
G
V
A
Y
-------
K
S
H
A
S
--
T
L
E
E
K
D
A
E
A
V
R
E
L
----------------------
V
K
E
Q
R
-----
G
L
Q
E
K
L
A
E
E
E
R
R
K
S
L
P
R
R
P
P
V
V
V
I
M
G
--------
H
VDHG
K
T
T
L
L
D
Y
L
R
K
S
R
I
A
E
-------
K
E
G
G
G
I
T
Q
H
V
G
A
F
E
V
K
T
P
Q
G
T
V
V
F
I
D
T
P
G
H
E
A
F
T
T
I
R
Q
R
G
A
K
---
V
A
D
I
A
V
I
V
I
A
A
D
--
D
G
I
M
P
Q
T
E
E
-
A
I
A
H
A
K
A
A
G
----
A
K
L
I
F
A
I
N
---------------------
K
I
D
L
P
-----
Q
A
D
P
E
K
V
K
R
Q
L
M
E
R
G
F
V
P
E
E
Y
G
G
D
A
I
V
I
P
I
S
A
K
T
G
---
Q
G
V
Q
D
L
L
E
M
I
L
L
L
A
E
L
E
D
Y
R
A
D
P
N
A
E
P
----
R
G
V
---
I
L
E
S
K
L
D
K
Q
A
G
--------
I
I
A
N
M
L
V
Q
E
G
T
F
-----------------
R
V
G
D
Y
V
V
A
G
E
A
Y
G
R
I
R
A
----------
M
M
D
A
D
G
N
Q
R
K
E
A
G
P
G
S
A
V
Q
V
L
------
G
F
Q
E
L
-------
P
H
-----------------------------------------
A
----
G
D
V
V
E
W
V
P
D
L
E
A
A
K
E
I
A
E
E
R
K
E
E
R
K
A
R
E
E
E
E
K
A
R
R
PRTMAELLR------
17
Fugue
83.09
11%
-183
- C6 -
2JGP
5
A:
[1-520]
RSEYVAPRS
V
W
E
A
R
L
A
Q
V
W
E
Q
V
L
N
--
V
P
Q
V
G
A
L
D
D
F
F
A
L
G
GH
S
L
R
A
M
R
V
L
S
-
S
M
H
N
E
Y
Q
V
D
I
P
L
R
I
L
F
E
--
K
P
T
I
Q
E
L
A
A
F
I
E
E
TAKGNVFSIEPVQKQA
Y
Y
P
V
S
S
A
Q
K
R
M
-----
Y
I
L
D
Q
F
E
G
V
G
I
S
Y
N
M
P
S
T
M
L
I
E
G
K
L
E
--------
R
-----
T
R
V
E
A
A
F
Q
R
L
I
A
R
H
E
S
L
R
T
S
F
A
V
V
N
G
E
P
V
Q
N
I
H
E
D
V
P
F
A
L
A
Y
S
E
V
T
E
E
E
A
R
E
L
V
S
-
S
L
V
Q
P
F
D
L
E
V
A
P
L
I
R
V
S
L
L
K
I
G
ED
R
Y
V
L
F
T
D
M
H
-
H
S
I
S
D
G
V
S
S
----
G
I
L
L
A
E
W
V
---------------------
Q
L
Y
Q
G
-----
D
V
L
P
E
L
R
I
Q
Y
K
D
F
A
V
W
Q
Q
E
F
S
Q
S
A
A
F
H
K
Q
E
A
Y
W
L
Q
T
F
A
D
D
I
P
V
L
N
L
P
T
D
F
T
R
P
S
-
T
Q
S
F
A
G
D
Q
C
T
----
I
G
A
G
K
A
L
T
E
G
L
H
Q
L
A
Q
A
T
G
T
T
L
Y
M
V
L
L
A
A
Y
N
V
L
L
A
K
Y
A
GQE
D
I
I
V
G
T
P
I
TGRSH
A
D
L
E
P
I
V
G
M
F
V
N
T
L
A
M
R
N
K
PQREKT
F
S
E
F
L
Q
E
V
K
Q
N
A
L
D
A
Y
G
H
-
Q
D
Y
P
F
E
E
L
V
E
K
L
A
I
A
RDLSRNP
L
F
D
T
V
F
T
F
Q
N
S
TEEVMTLPE
C
T
L
A
P
F
M
TDETGQHAK
F
D
L
T
F
S
A
T
----
E
E
R
E
E
M
T
I
G
V
E
Y
S
T
S
L
F
T
R
E
T
M
E
R
F
S
R
H
F
L
T
I
A
A
S
I
V
Q
NPHIRLGEIDML
16
Fugue
68.08
7%
-141
- C6 -
1PW4
-
GLPT_ECOLI
A:
[5-451]
-------FKP
A
P
H
K
A
R
L
P
A
A
E
I
D
P
T
Y
R
R
L
R
W
Q
I
F
L
G
I
F
F
G
--
Y
A
A
Y
Y
L
V
R
---
K
N
F
A
L
A
M
P
Y
L
V
E
Q
G
F
S
--
R
G
D
L
G
F
A
L
S
G
I
S
I
----------------------
A
Y
G
F
S
-----
K
F
I
M
G
S
V
S
D
R
S
N
P
R
V
F
L
P
A
G
L
I
L
A
A
A
--------
V
-----
M
L
F
M
G
F
V
P
W
A
T
S
S
I
A
V
M
F
V
L
L
F
L
C
G
W
F
Q
G
M
--
G
W
P
P
C
G
R
T
M
V
H
W
W
S
Q
K
E
R
G
G
I
V
S
-
V
W
N
C
A
H
N
V
G
G
G
I
P
P
L
L
F
L
L
G
M
A
--
W
F
N
D
W
H
A
A
L
-
Y
M
P
A
F
C
A
I
L
----
V
A
L
F
A
F
A
M
MRDTPQSCGLPPIEEYKNDTA
K
Q
I
F
M
-----
Q
Y
V
L
P
N
K
L
L
W
Y
I
A
I
A
N
V
F
V
Y
L
L
R
Y
G
I
L
D
W
S
P
T
Y
L
K
---
E
V
K
H
F
A
L
D
K
S
S
W
A
Y
F
L
-
Y
E
Y
A
G
I
P
G
T
L
----
L
C
G
---
W
M
S
D
K
V
F
R
G
N
R
G
A
T
G
V
F
F
M
T
L
V
T
I
A
T
I
V
Y
W
M
-----------------
N
P
A
G
N
P
T
V
D
M
I
C
M
I
V
I
G
----------
F
L
I
Y
G
P
V
M
L
I
G
L
H
A
L
E
L
A
P
K
K
A
A
G
T
A
A
G
F
T
G
L
-------
F
G
Y
L
G
G
S
V
A
A
S
-------------------------
A
I
V
G
Y
T
V
D
FFG
W
D
G
G
F
M
V
M
I
G
G
S
I
L
A
V
I
L
L
I
V
V
M
I
G
E
K
R
R
H
E
Q
L
L
Q
E
LVP------------
1
PsiBlast_PDB
54.86
23%
-83
- C5 -
3CZH
6
CP2R1_HUMAN
A:
[134-235]
-------------
E
E
T
K
F
F
N
D
A
I
E
T
Y
K
G
R
P
F
D
F
K
Q
L
I
T
N
A
--
V
S
N
I
T
N
L
I
I
-
F
G
E
R
F
T
Y
E
D
T
D
F
Q
H
M
I
E
L
F
S
E
N
V
E
L
A
A
S
A
S
V
F
----------------------
L
Y
N
A
F
-----
P
W
---------
I
G
I
L
P
F
G
K
H
Q
Q
L
F
R
N
--------
A
-----
A
V
V
Y
D
F
L
S
R
L
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
54.20
14%
-149
- C4 -
4QPI
5
?
A:
[3-275]
---------------------------------------------------------
D
D
S
G
G
F
S
T
T
V
S
T
--
E
Q
N
V
P
D
P
Q
V
G
I
T
T
----------------------
M
R
M
D
V
SGVQA
P
V
G
A
I
T
T
I
E
D
P
V
L
A
K
K
V
P
E
T
F
P
E
L
K
P
GESRHTSD
H
-----
M
S
I
Y
K
F
M
G
R
-------
S
H
F
L
C
T
F
T
F
N
S
N
N
K
E
Y
T
F
P
I
T
L
--
S
S
T
S
N
P
P
H
G
L
P
S
T
L
R
-
W
F
F
N
L
F
Q
L
Y
R
-
G
P
L
D
L
T
I
I
I
T
G
--
A
T
D
V
D
G
M
A
W
-
F
T
P
---
V
G
L
----
A
V
D
T
P
W
V
E
---------------------
K
---------------
E
S
A
L
Q
I
D
Y
K
T
A
L
G
A
V
R
F
N
T
R
R
T
G
--
N
I
Q
I
---
R
L
P
W
Y
S
Y
L
Y
A
V
S
G
A
L
D
-
G
L
G
D
K
T
D
S
T
F
G
L
--
V
S
I
---
Q
I
A
N
Y
N
H
S
D
E
Y
L
S
F
S
C
Y
L
S
V
T
E
Q
S
E
F
Y
F
P
R
A
-----------------
P
L
N
S
N
A
M
L
S
T
E
S
M
-------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
53.27
15%
-166
- C6 -
1Q77
-
Y178_AQUAE
A:
[1-138]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
A
M
K
V
L
L
V
L
T
D
A
YSDC
E
K
A
I
T
Y
A
V
---------------------
N
F
S
E
K
LGAE
L
D
I
L
A
V
L
E
D
V
Y
N
L
E
R
A
N
V
T
F
G
L
P
F
P
P
---
E
I
K
E
E
S
K
---
K
R
I
E
R
R
L
R
E
V
W
E
K
L
T
--
G
S
T
E
I
P
G
V
E
Y
R
I
GP
L
S
E
---
E
V
K
K
F
V
E
G
K
G
Y
E
L
V
V
W
A
C
Y
P
S
A
Y
L
C
K
V
I
D
G
L
-----------------
N
L
A
S
L
I
V
K
------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
48.20
11%
-70
- C6 -
4OB4
-
?
A:
[3-71]
------------
S
E
Y
A
K
Q
L
G
A
K
L
R
A
I
R
T
Q
Q
G
L
S
L
H
G
V
E
E
K
--
S
Q
G
R
W
K
A
V
V
-
V
G
S
Y
E
R
G
D
----
R
A
V
T
V
--
Q
R
L
A
E
L
A
D
F
Y
G
V
P
----------------------
V
Q
E
L
L
-----
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
35.17
32%
351
* C5 *
1PLP
-
?
?:
[1-25]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
K
V
Q
Y
L
T
R
---
S
A
I
R
R
A
S
-
T
I
E
M
P
Q
Q
A
-
C
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
34.93
13%
268
* C6 *
2DYO
-
ATG16_YEAST
B:
[22-57]
------------
D
S
M
D
D
L
L
I
R
R
L
T
D
R
N
D
K
E
A
H
L
N
E
L
F
Q
D
N
--
S
G
A
I
G
G
N
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
27.12
26%
319
- C5 -
2LX0
-
?
A:
[10-29]
---------------------------------------
A
--
G
L
V
A
L
L
T
F
L
A
F
G
F
W
L
F
K
Y
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
26.84
41%
545
- C5 -
1ZRV
-
SPING_PSEUS
A:
[5-21]
--------------------------------------------------------------------------------------------------------------------------
K
V
A
D
K
V
L
L
L
K
Q
L
R
I
M
R
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
24.80
17%
904
- C5 -
2K9J
-
?
B:
[715-726]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
K
L
L
I
T
I
H
D
R
K
E
--------------------
18
Fugue
23.63
29%
458
- C6 -
1T01
-
B:
[1-24]
---------------------------------------------------------------------------------------------------------------------
G
R
P
L
L
Q
A
A
K
G
L
A
G
A
V
S
E
L
L
R
S
A
Q
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
16.50
8%
972
- C2 -
1ECI
-
ECAB_ECTTU
B:
[19-30]
-----------------------------------------------------------------------------------------------------------
K
C
E
G
-----
S
I
A
T
M
I
K
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
15.07
8%
1043
- C5 -
1ECI
-
ECAA_ECTTU
A:
[21-32]
-----------------------------------------------------------------------------------------------------------
K
C
S
G
-----
D
I
A
T
Y
I
K
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
13.68
42%
998
- C5 -
1WN4
-
A:
[10-21]
------------------------------------------------------------------------------------------------------------------------
L
L
E
E
A
L
V
A
F
A
K
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
8.89
20%
777
- C5 -
2QFA
-
INCE_HUMAN
C:
[30-44]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
V
W
L
E
E
I
Q
E
E
A
E
R
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
7.22
18%
1191
- C1 -
1WN8
-
A:
[5-15]
-------------------------------------------------------------------------------------------------------------------------
S
E
T
T
L
T
M
F
L
K
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
4.75
5%
1009
- C3 -
3UKW
1
?
C:
[7-23]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
R
-----
K
R
P
L
E
W
D
E
D
E
E
P
P
R
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------