@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1844: (2016-03-29 )
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDPVGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIMFFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI
Atome Classification :
(20 SA)
---.........10........20........30........40........50...-..----...60.-....----------...70........80........90........100.-......110-........120.......130...-....140.......150.......160.......170.....-..180.......--190.---......200.......210.......220.......230......--------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---
M
K
I
F
I
CEDD
P
K
Q
R
E
N
M
V
T
I
I
K
N
Y
I
M
I
EEKP
M
E
I
A
LATD
N
P
Y
E
V
L
E
Q
AKNMND
I
G
-
C
Y
----
F
L
D
I
Q
L
-STDI----------N
G
I
KLG
S
E
I
RKHDPVG
N
I
I
F
V
TSHSE
L
T
Y
L
T
F
V
Y
K
V
A
-
A
M
D
F
I
FK-D-
D
P
A
E
L
R
T
R
I
I
D
C
L
E
T
A
H
T
R
L
Q
L
LS-KDNS
V
E
T
I
E
L
KRGS
N
S
V
Y
V
Q
YD
D
I
M
F
FESSTKS
H
R
L
I
A
HLDN-
R
Q
I
E
F
YG
N
L
K
E
L
--
S
Q
L
D
---
D
R
F
F
R
C
H
N
S
F
V
V
NRHNIESIDSK
E
R
I
V
Y
F
KN
K
E
H
C
Y
A
S
V
R
NVKKI--------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
83.95
100%
-125
- C3 -
4G4K
3
AGRA_STAAU
A:
[6-103]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
I
E
L
K
R
G
S
N
S
V
Y
V
Q
Y
D
D
I
M
F
F
E
S
S
T
K
S
H
R
L
I
A
H
L
D
N
-
R
Q
I
E
F
Y
G
N
L
K
E
L
--
S
Q
L
D
---
D
R
F
F
R
C
H
N
S
F
V
V
N
R
H
N
I
E
S
I
D
S
K
E
R
I
V
Y
F
K
N
K
E
H
C
Y
A
S
V
R
N
V
K
K
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
82.65
100%
-124
- C3 -
4G4K
2
B:
[4-103]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
E
T
I
E
L
K
R
G
S
N
S
V
Y
V
Q
Y
D
D
I
M
F
F
E
S
S
T
K
S
H
R
L
I
A
H
L
D
N
-
R
Q
I
E
F
Y
G
N
L
K
E
L
--
S
Q
L
D
---
D
R
F
F
R
C
H
N
S
F
V
V
N
R
H
N
I
E
S
I
D
S
K
E
R
I
V
Y
F
K
N
K
E
H
C
Y
A
S
V
R
N
V
K
K
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
81.76
100%
-119
- C3 -
3BS1
4
A:
[2-103]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
S
V
E
T
I
E
L
K
R
G
S
N
S
V
Y
V
Q
Y
D
D
I
M
F
F
E
S
S
T
K
S
H
R
L
I
A
H
L
D
N
-
R
Q
I
E
F
Y
G
N
L
K
E
L
--
S
Q
L
D
---
D
R
F
F
R
C
H
N
S
F
V
V
N
R
H
N
I
E
S
I
D
S
K
E
R
I
V
Y
F
K
N
K
E
H
C
Y
A
S
V
R
N
V
K
K
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
81.63
99%
-118
- C3 -
3BS1
4
A:
[1-103]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
N
S
V
E
T
I
E
L
K
R
G
S
N
S
V
Y
V
Q
Y
D
D
I
M
F
F
E
S
S
T
K
S
H
R
L
I
A
H
L
D
N
-
R
Q
I
E
F
Y
G
N
L
K
E
L
--
S
Q
L
D
---
D
R
F
F
R
C
H
N
S
F
V
V
N
R
H
N
I
E
S
I
D
S
K
E
R
I
V
Y
F
K
N
K
E
H
C
Y
A
S
V
R
N
V
K
K
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
74.37
31%
-120
- C3 -
4CBV
-
?
A:
[54-240]
----------------------------------------------------------
L
Y
----
F
L
A
I
D
I
H
G
I
E
K
----------
K
G
F
E
V
A
Q
L
I
R
H
Y
N
P
Y
A
I
I
V
F
I
T
S
R
S
E
F
A
T
L
T
Y
K
Y
Q
V
S
-
A
L
D
F
V
D
K
-
D
-
I
N
D
E
M
F
K
K
R
I
E
Q
-
N
I
F
Y
T
K
S
M
L
L
E
-
N
E
D
V
V
D
Y
F
D
Y
N
Y
K
G
N
D
L
K
I
P
Y
H
D
I
L
Y
I
E
T
T
G
V
S
H
K
L
R
I
I
G
K
N
-
F
A
K
E
F
Y
G
T
M
T
D
I
--
Q
E
K
D
K
HT
Q
R
F
Y
S
P
H
K
S
F
L
V
N
I
G
N
I
R
E
I
D
R
K
N
L
E
I
V
F
Y
E
D
H
R
C
P
I
S
R
L
K
I
R
K
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
66.02
23%
-115
- C3 -
3B2N
1
?
A:
[5-120]
----
S
L
I
I
A
E
D
Q
N
M
L
R
Q
A
M
V
Q
L
I
K
-----
L
H
G
D
F
E
I
L
A
D
T
D
N
G
L
D
A
M
K
L
I
E
E
-
Y
N
P
N
-
V
V
----
I
L
D
I
E
M
-
P
G
-
M
----------
T
G
L
E
V
L
A
E
I
R
K
K
H
L
N
I
K
V
I
I
V
T
T
F
K
R
P
G
Y
F
E
K
A
V
V
N
D
-
V
D
A
Y
V
L
K
-
E
-
R
S
I
E
---
E
L
V
E
T
I
N
K
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
Fugue
62.69
18%
-71
- C3 -
1NY5
8
?
A:
[1-384]
---
M
N
V
L
V
I
E
D
D
K
V
F
R
G
L
L
E
E
Y
L
S
M
K
----
G
I
K
V
E
S
A
E
R
G
K
E
A
Y
K
L
L
S
E
----
K
H
F
N
-
V
V
----
L
L
D
L
L
L
-
P
-
D
V
----------
N
G
L
E
I
L
K
W
I
K
E
R
S
P
E
T
E
V
I
V
I
T
G
H
G
T
I
K
T
A
V
E
A
M
K
M
G
-
A
Y
D
F
L
T
K
-
P
C
M
L
E
E
I
E
L
T
I
N
K
A
I
E
H
R
K
L
R
K
E
N
E
L
-
L
R
R
E
K
D
L
K
E
E
E
Y
V
F
E
S
P
K
M
K
E
I
L
E
K
I
K
K
I
S
C
A
E
C
P
V
L
I
T
G
E
S
-------
G
V
G
K
E
V
V
A
R
L
I
H
---
K
L
S
D
R
S
K
E
P
F
V
A
L
N
V
A
S
I
P
R
D
I
F
E
A
E
L
F
G
Y
E
K
G
A
F
T
G
A
V
S
S
K
E
G
F
F
E
L
A
DG
G
T
L
F
L
D
EIGELS
L
E
A
Q
A
K
L
L
R
V
I
E
SG
K
F
Y
R
LGGRK
E
I
E
V
N
V
R
I
L
A
A
T
NRN
I
K
E
L
V
K
E
GKFR
E
D
L
Y
Y
R
L
G
V
I
E
I
E
I
P
P
LRERKED
I
I
P
L
A
N
H
F
L
K
K
F
S
R
K
Y
AKEVEGFT
K
S
A
Q
E
L
L
L
S
YPWYGN
V
R
E
L
K
N
V
I
E
R
A
V
L
F
SEGKFID
R
G
E
L
S
C
L
V
28
HHSearch
61.88
19%
-132
- C3 -
3F6C
1
EVGA_ECOLI
A:
[3-116]
----
N
A
I
I
I
D
D
H
P
L
A
I
A
A
I
R
N
L
L
I
-----
K
N
-
D
I
E
I
L
A
E
L
T
E
G
G
S
A
V
Q
R
V
E
T
-
L
K
P
D
-
I
V
----
I
I
D
V
D
I
-
P
G
-
V
----------
N
G
I
Q
V
L
E
T
L
R
K
R
Q
Y
S
G
I
I
I
I
V
S
A
K
---
F
Y
G
K
H
C
A
D
A
G
-
A
N
G
F
V
S
K
-
K
-
E
G
M
N
---
N
I
I
A
A
I
E
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
60.06
20%
-119
- C3 -
3W9S
2
?
A:
[2-106]
----
K
I
L
V
I
E
D
D
A
L
L
L
Q
G
L
I
L
A
M
Q
-----
S
E
-
G
Y
V
C
-
D
G
V
S
T
A
H
E
A
A
L
S
L
A
S
-
N
H
Y
S
-
L
I
----
V
L
D
L
G
L
-
P
D
-
E
----------
D
G
L
H
F
L
S
R
M
R
R
E
K
M
T
Q
P
V
L
I
L
T
A
R
D
T
L
E
D
R
I
S
G
L
D
T
G
-
A
D
D
Y
L
V
K
-
P
-
F
A
L
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
59.90
18%
-118
- C3 -
3CFY
-
?
A:
[4-117]
----
R
V
L
L
V
E
D
S
T
S
L
A
I
L
Y
K
Q
Y
V
K
-----
D
E
-
P
Y
D
I
-
F
H
V
E
T
G
R
D
A
I
Q
F
I
E
R
-
S
K
P
Q
-
L
I
----
I
L
D
L
K
L
-
P
D
-
M
----------
S
G
E
D
V
L
D
W
I
N
Q
N
D
I
P
T
S
V
I
I
A
T
A
H
G
S
V
D
L
A
V
N
L
I
Q
K
G
-
A
E
D
F
L
E
K
-
P
-
I
N
A
D
---
R
L
K
T
S
V
A
L
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
59.40
19%
-105
- C3 -
1DBW
1
FIXJ_RHIME
A:
[5-117]
----
T
V
H
I
V
D
D
E
E
P
V
R
K
S
L
A
F
M
L
T
-----
M
N
-
G
F
A
V
-
K
M
H
Q
S
A
E
A
F
L
A
F
A
P
D
-
V
R
N
G
-
V
L
----
V
T
D
L
R
M
-
P
D
-
M
----------
S
G
V
E
L
L
R
N
L
G
D
L
K
I
N
I
P
S
I
V
I
T
G
H
G
D
V
P
M
A
V
E
A
M
K
A
G
-
A
V
D
F
I
E
K
-
P
-
F
E
D
T
---
V
I
I
E
A
I
E
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
58.71
12%
-109
- C3 -
3HV2
1
?
A:
[16-130]
----
E
I
L
L
V
D
S
Q
E
V
I
L
Q
R
L
Q
Q
L
L
S
-----
P
L
-
P
Y
T
L
-
H
F
A
R
D
A
T
Q
A
L
Q
L
L
A
S
-
R
E
V
D
-
L
V
----
I
S
A
A
H
L
-
P
Q
-
M
----------
D
G
P
T
L
L
A
R
I
H
Q
Q
Y
P
S
T
T
R
I
L
L
T
G
D
P
D
L
K
L
I
A
K
A
I
N
E
G
E
I
Y
R
Y
L
S
K
-
P
-
W
D
D
Q
---
E
L
L
L
A
L
R
Q
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
58.12
22%
-96
- C3 -
3CZ5
2
?
A:
[7-139]
----
R
I
M
L
V
D
D
H
P
I
V
R
E
G
Y
R
R
------
L
I
E
R
R
P
G
---------
Y
A
V
V
A
E
A
A
D
A
G
E
---
A
Y
----
R
L
Y
R
E
T
-
T
P
D
I
V
V
M
D
LTLPGP
G
G
I
E
A
T
R
H
I
R
Q
W
D
G
A
A
R
I
L
I
F
T
M
H
Q
G
S
A
F
A
L
K
A
F
E
A
G
-
A
S
G
Y
V
T
K
S
S
-
D
P
A
E
L
----
V
Q
A
I
E
A
I
L
A
G
R
R
A
M
S
-
P
D
I
A
Q
E
I
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
58.10
18%
-114
- C3 -
3CZ5
2
?
A:
[7-113]
----
R
I
M
L
V
D
D
H
P
I
V
R
E
G
Y
R
R
L
I
E
-----
R
R
P
G
Y
A
V
V
A
E
A
A
D
A
G
E
A
Y
R
L
Y
R
E
-
T
T
P
D
-
I
V
----
V
M
D
L
T
L
-
P
G
-
P
----------
G
G
I
E
A
T
R
H
I
R
Q
W
D
G
A
A
R
I
L
I
F
T
M
H
Q
G
S
A
F
A
L
K
A
F
E
A
G
-
A
S
G
Y
V
T
K
-
S
-
S
D
P
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
57.73
19%
-112
- C3 -
1SRR
1
SP0F_BACSU
A:
[5-116]
----
K
I
L
I
V
D
D
Q
S
G
I
R
I
L
L
N
E
V
F
N
-----
K
E
-
G
Y
Q
T
-
F
Q
A
A
N
G
L
Q
A
L
D
I
V
T
K
-
E
R
P
D
-
L
V
----
L
L
D
M
K
I
-
P
G
-
M
----------
D
G
I
E
I
L
K
R
M
K
V
I
D
E
N
I
R
V
I
I
M
T
A
Y
G
E
L
D
M
I
Q
E
S
K
E
L
G
-
A
L
T
H
F
A
K
-
P
-
F
D
I
D
---
E
I
R
D
A
V
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
57.50
29%
-109
- C3 -
4MLD
-
?
A:
[1-111]
---
M
K
V
L
I
L
E
D
V
I
E
H
Q
V
R
L
E
R
I
L
D
E
--
I
S
K
E
S
N
I
P
I
S
Y
K
T
T
G
K
V
R
E
F
E
E
Y
I
E
N
D
E
V
N
Q
L
Y
----
F
L
E
I
D
I
H
G
I
E
K
----------
K
G
F
E
V
A
Q
L
I
R
H
Y
N
P
Y
A
I
I
V
F
I
T
S
R
S
E
F
A
T
L
T
Y
K
Y
Q
V
S
-
A
L
D
F
V
D
K
-
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
56.92
16%
-84
- C3 -
1KGS
5
?
A:
[4-204]
----
R
V
L
V
V
E
D
E
R
D
L
A
D
L
I
T
E
A
L
K
-----
K
E
-
M
F
T
V
-
D
V
C
Y
D
G
E
E
G
M
Y
M
A
L
N
-
E
P
F
D
-
V
V
----
I
L
D
I
M
L
-
P
V
-
H
----------
D
G
W
E
I
L
K
S
M
R
E
S
G
V
N
T
P
V
L
M
L
T
A
L
S
D
V
E
Y
R
V
K
G
L
N
M
G
-
A
D
D
Y
L
P
K
-
P
-
F
D
L
R
---
E
L
I
A
R
V
R
A
L
I
R
R
K
S
E
S
K
S
T
K
L
V
C
G
D
L
I
L
D
T
A
T
K
K
A
Y
R
G
S
K
E
I
D
L
T
K
K
E
Y
Q
I
L
E
Y
L
--
V
M
N
K
N
R
V
V
T
K
E
E
L
Q
E
H
--
L
W
------
V
F
S
D
V
L
R
S
H
I
K
N
L
R
K
K
V
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
56.50
22%
-102
- C3 -
3H5I
1
?
A:
[7-119]
----
K
I
L
I
V
E
D
S
K
F
Q
A
K
T
I
A
N
I
L
N
K
Y
----
G
Y
T
V
E
I
A
L
T
G
E
A
A
V
E
K
V
S
G
-------
G
-
W
Y
PDLI
L
M
D
I
E
L
-
G
E
G
M
----------
D
G
V
Q
T
A
L
A
I
Q
Q
I
S
E
L
-
P
V
V
F
L
T
A
H
T
E
P
A
V
V
E
K
I
R
S
V
T
-
A
Y
G
Y
V
M
K
-
S
-
A
T
E
Q
V
L
I
T
I
V
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
56.16
22%
-104
* C3 *
3HDG
2
?
A:
[9-126]
----
K
I
L
I
V
E
D
D
T
D
A
R
E
W
L
S
T
I
I
S
-----
N
H
-
F
P
E
-
V
W
S
A
G
D
G
E
E
G
E
R
L
F
G
L
-
H
A
P
D
-
V
I
----
I
T
D
I
R
M
-
P
K
-
L
----------
G
G
L
E
M
L
D
R
I
K
A
G
G
A
K
P
Y
V
I
V
I
S
A
F
S
E
M
K
Y
F
I
K
A
I
E
L
G
-
V
H
L
F
L
P
K
-
P
-
I
E
P
G
---
R
L
M
E
T
L
E
D
F
R
H
I
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
55.51
13%
-86
- C3 -
1S8N
1
PDTAR_MYCTU
A:
[11-200]
AVP
R
R
V
L
I
A
E
D
E
A
L
I
R
M
D
L
A
E
M
L
R
E
------
E
G
Y
E
I
V
G
E
A
G
D
G
Q
E
A
V
E
L
A
E
L
H
K
-
P
D
-
L
V
----
I
M
D
V
K
M
-
P
-
R
R
----------
D
G
I
D
A
A
S
E
I
A
S
K
R
I
A
-
P
I
V
V
L
T
A
F
S
Q
R
D
L
V
E
R
A
R
D
A
G
-
A
M
A
Y
L
V
K
-
P
F
S
I
S
D
L
I
P
A
I
E
L
A
V
S
R
F
R
E
I
T
A
L
E
G
-
E
V
A
T
---
L
S
E
R
L
E
T
R
K
L
V
E
R
A
K
G
L
L
Q
T
K
H
G
---
M
T
E
P
D
A
F
K
W
-
I
Q
R
A
A
M
D
R
R
T
T
M
--
K
R
V
A
---
E
V
V
L
E
T
L
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------