@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1939: (2016-03-30 )
MNSAKLIDHTLLKPESTRTQIDQIIDEAKAYHFKSVCVNPTHVKYAAERLADSEVLVCTVIGFPLGASTTATKAFETEDAIQNGADEIDMVINIGALKDGRFDDVQQDIEAVVKAAKGHTVKVIIETVLLDHDEIVKASELTKVAGADFVKTSTGFAGGGATAEDVKLMKDTVGADVEVKASGGVRNLEDFNKMVEAGATRIGASAGVQIMQGLEADSDY
Atome Classification :
(32 SA)
---------.........10........20........30--.--.......40........50.---.---......60........70........80........90........100---........110.....--..120.....----..130.----.......140..---.....150....-..-.160.......170-..-----..---.-----....180.......190.......200...---------....210.......220
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------MNS
A
K
L
I
D
H
TLLKPE
S
T
R
T
Q
I
D
Q
I
I
D
E
A
K
A
Y
--
H
--
F
K
SVCVN
P
T
H
V
K
Y
A
A
E
RLAD---S---
E
V
L
V
C
T
V
IGFPLGASTTATKAFE
T
E
D
A
I
QNGAD
E
I
D
M
V
I
N
I
GALKDG
R
----
F
D
D
V
Q
Q
D
I
E
A
V
V
K
AAK--G
H
T
V
K
V
I
I
E
T
----
V
LL-
D
H
----
D
E
I
V
K
A
S
E
L
T
K
V---AGA
D
F
V
KTSTGF-AG-GGA
T
A
E
D
V
K
L
M
K
---
D
T-----VG---A-----
D
V
E
V
K
ASGGVR
N
L
E
D
F
N
K
M
V
E
AGATRIG
A
S
---------
A
G
V
Q
I
M
Q
GLEADSDY-
51
HHSearch
97.31
53%
-88
- C2 -
3NGJ
3
?
A:
[25-239]
---------
A
T
L
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
--
F
A
S
V
C
V
N
P
T
W
V
P
L
C
A
E
L
L
K
G
---
T
---
G
V
K
V
C
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
I
N
I
G
M
V
K
A
K
K
----
Y
D
D
V
E
K
D
V
K
A
V
V
D
A
S
G
--
K
A
L
T
K
V
I
I
E
C
----
C
Y
L
-
T
N
----
E
E
K
V
E
V
C
K
R
C
V
A
---
A
G
A
E
Y
V
K
T
S
T
G
F
-
G
T
-
H
G
A
T
P
E
D
V
K
L
M
K
---
D
T
-----
V
G
---
D
-----
K
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
G
A
S
R
I
G
A
S
---------
A
G
I
A
I
L
N
G
I
H
------
23
PsiBlast_CBE
97.01
54%
-93
- C2 -
3NGJ
5
?
B:
[28-238]
------------
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
--
F
A
S
V
C
V
N
P
T
W
V
P
L
C
A
E
L
L
K
G
---
T
---
G
V
K
V
C
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
I
N
I
G
M
V
K
A
K
K
----
Y
D
D
V
E
K
D
V
K
A
V
V
D
A
S
G
--
K
A
L
T
K
V
I
I
E
C
----
C
Y
L
-
T
N
----
E
E
K
V
E
V
C
K
R
C
V
A
---
A
G
A
E
Y
V
K
T
S
T
G
F
-
G
T
-
H
G
A
T
P
E
D
V
K
L
M
K
---
D
T
-----
V
G
---
D
-----
K
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
G
A
S
R
I
G
A
S
---------
A
G
I
A
I
L
N
G
I
-------
50
HHSearch
96.78
54%
-84
* C2 *
3R12
3
DEOC_THEMA
A:
[42-256]
----------
D
V
K
S
A
I
E
H
T
N
L
K
P
F
A
T
P
D
D
I
K
K
L
C
L
E
A
R
E
N
--
R
--
F
H
G
V
C
V
N
P
C
Y
V
K
L
A
R
E
E
L
E
G
---
T
---
D
V
K
V
V
T
V
V
G
F
P
L
G
A
N
E
T
R
T
K
A
H
E
A
I
F
A
V
E
S
G
A
D
E
I
D
M
V
I
N
V
G
M
L
K
A
K
E
----
W
E
Y
V
Y
E
D
I
R
S
V
V
E
S
V
K
--
G
K
V
V
K
V
I
I
E
T
----
C
Y
L
-
D
T
----
E
E
K
I
A
A
C
V
I
S
K
L
---
A
G
A
H
F
V
K
T
S
T
G
F
-
G
T
-
G
G
A
T
A
E
D
V
H
L
M
K
---
W
I
-----
V
G
---
D
-----
E
M
G
V
K
A
S
G
G
I
R
T
F
E
D
A
V
K
M
I
M
Y
G
A
D
R
I
G
T
S
---------
S
G
V
K
I
V
Q
G
G
E
E
-----
21
PsiBlast_CBE
96.47
54%
-93
- C2 -
3NGJ
5
?
D:
[28-238]
------------
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
--
F
A
S
V
C
V
N
P
T
W
V
P
L
C
A
E
L
L
K
G
---
T
---
G
V
K
V
C
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
I
N
I
G
M
V
K
A
K
K
----
Y
D
D
V
E
K
D
V
K
A
V
V
D
A
S
G
--
K
A
L
T
K
V
I
I
E
C
----
C
Y
L
-
T
N
----
E
E
K
V
E
V
C
K
R
C
V
A
---
A
G
A
E
Y
V
K
T
S
T
G
F
-
G
T
-
H
G
A
T
P
E
D
V
K
L
M
K
---
D
T
-----
V
G
---
D
-----
K
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
G
A
S
R
I
G
A
S
---------
A
G
I
A
I
L
N
G
I
-------
1
PsiBlast_PDB
96.36
54%
-91
- C2 -
3NGJ
3
?
A:
[28-238]
------------
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
--
F
A
S
V
C
V
N
P
T
W
V
P
L
C
A
E
L
L
K
G
---
T
---
G
V
K
V
C
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
I
N
I
G
M
V
K
A
K
K
----
Y
D
D
V
E
K
D
V
K
A
V
V
D
A
S
G
--
K
A
L
T
K
V
I
I
E
C
----
C
Y
L
-
T
N
----
E
E
K
V
E
V
C
K
R
C
V
A
---
A
G
A
E
Y
V
K
T
S
T
G
F
-
G
T
-
H
G
A
T
P
E
D
V
K
L
M
K
---
D
T
-----
V
G
---
D
-----
K
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
G
A
S
R
I
G
A
S
---------
A
G
I
A
I
L
N
G
I
-------
22
PsiBlast_CBE
95.52
54%
-91
- C2 -
3NGJ
5
?
C:
[28-238]
------------
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
--
F
A
S
V
C
V
N
P
T
W
V
P
L
C
A
E
L
L
K
G
---
T
---
G
V
K
V
C
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
I
N
I
G
M
V
K
A
K
K
----
Y
D
D
V
E
K
D
V
K
A
V
V
D
A
S
G
--
K
A
L
T
K
V
I
I
E
C
----
C
Y
L
-
T
N
----
E
E
K
V
E
V
C
K
R
C
V
A
---
A
G
A
E
Y
V
K
T
S
T
G
F
-
G
T
-
H
G
A
T
P
E
D
V
K
L
M
K
---
D
T
-----
V
G
---
D
-----
K
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
G
A
S
R
I
G
A
S
---------
A
G
I
A
I
L
N
G
I
-------
3
PsiBlast_PDB
95.12
54%
-87
- C2 -
3R13
5
DEOC_THEMA
A:
[47-255]
---------------
I
E
H
T
N
L
K
P
F
A
T
P
D
D
I
K
K
L
C
L
E
A
R
E
N
--
R
--
F
H
G
V
C
V
N
P
C
Y
V
K
L
A
R
E
E
L
E
G
---
T
---
D
V
K
V
V
T
V
V
G
F
P
L
G
A
N
E
T
R
T
K
A
H
E
A
I
F
A
V
E
S
G
A
D
E
I
D
M
V
I
N
V
G
M
L
K
A
K
E
----
W
E
Y
V
Y
E
D
I
R
S
V
V
E
S
V
K
--
G
K
V
V
K
V
I
I
E
T
----
C
Y
L
-
D
T
----
E
E
K
I
A
A
C
V
I
S
K
L
---
A
G
A
H
F
V
K
T
S
T
G
F
-
G
T
-
G
G
A
T
A
E
D
V
H
L
M
K
---
W
I
-----
V
G
---
D
-----
E
M
G
V
K
A
S
G
G
I
R
T
F
E
D
A
V
K
M
I
M
Y
G
A
D
R
I
G
T
S
---------
S
G
V
K
I
V
Q
G
G
E
------
2
PsiBlast_PDB
94.55
54%
-87
- C2 -
3R12
3
DEOC_THEMA
A:
[47-255]
---------------
I
E
H
T
N
L
K
P
F
A
T
P
D
D
I
K
K
L
C
L
E
A
R
E
N
--
R
--
F
H
G
V
C
V
N
P
C
Y
V
K
L
A
R
E
E
L
E
G
---
T
---
D
V
K
V
V
T
V
V
G
F
P
L
G
A
N
E
T
R
T
K
A
H
E
A
I
F
A
V
E
S
G
A
D
E
I
D
M
V
I
N
V
G
M
L
K
A
K
E
----
W
E
Y
V
Y
E
D
I
R
S
V
V
E
S
V
K
--
G
K
V
V
K
V
I
I
E
T
----
C
Y
L
-
D
T
----
E
E
K
I
A
A
C
V
I
S
K
L
---
A
G
A
H
F
V
K
T
S
T
G
F
-
G
T
-
G
G
A
T
A
E
D
V
H
L
M
K
---
W
I
-----
V
G
---
D
-----
E
M
G
V
K
A
S
G
G
I
R
T
F
E
D
A
V
K
M
I
M
Y
G
A
D
R
I
G
T
S
---------
S
G
V
K
I
V
Q
G
G
E
------
48
HHSearch
93.33
48%
-87
- C2 -
3OA3
1
?
A:
[57-274]
----------
S
I
A
Q
I
I
D
H
T
Q
L
S
L
S
A
T
G
S
Q
I
D
V
L
C
A
E
A
K
E
Y
--
G
--
F
A
T
V
C
V
R
P
D
Y
V
S
R
A
V
Q
Y
L
Q
G
---
T
---
Q
V
G
V
T
C
V
I
G
F
H
E
G
T
Y
S
T
D
Q
K
V
S
E
A
K
R
A
M
Q
N
G
A
S
E
L
D
M
V
M
N
Y
P
W
L
S
E
K
R
----
Y
T
D
V
F
Q
D
I
R
A
V
R
L
A
A
K
--
D
A
I
L
K
V
I
L
E
T
----
S
Q
L
-
T
A
----
D
E
I
I
A
G
C
V
L
S
S
L
---
A
G
A
D
Y
V
K
T
S
T
G
F
-
N
G
-
P
G
A
S
I
E
N
V
S
L
M
S
---
A
V
-----
C
D
S
LQ
S
-----
E
T
R
V
K
A
S
G
G
I
R
T
I
E
D
C
V
K
M
V
R
A
G
A
E
R
L
G
A
S
---------
A
G
V
K
I
V
N
E
T
R
L
-----
54
HHSearch
91.88
42%
-88
- C2 -
1MZH
-
DEOC_AQUAE
A:
[2-214]
---------
I
D
V
R
K
Y
I
D
N
A
A
L
K
P
H
L
S
E
K
E
I
E
E
F
V
L
K
S
E
E
L
--
G
--
I
Y
A
V
C
V
N
P
Y
H
V
K
L
A
S
S
I
A
K
--------
K
V
K
V
C
C
V
I
G
F
P
L
G
L
N
K
T
S
V
K
V
K
E
A
V
E
A
V
R
D
G
A
Q
E
L
D
I
V
W
N
L
S
A
F
K
S
E
K
----
Y
D
F
V
V
E
E
L
K
E
I
F
R
E
T
P
--
S
A
V
H
K
V
I
V
E
T
----
P
Y
L
-
N
E
----
E
E
I
K
K
A
V
E
I
C
I
E
---
A
G
A
D
F
I
K
T
S
T
G
F
-
A
P
-
R
G
T
T
L
E
E
V
R
L
I
K
---
S
S
-----
A
K
---
G
-----
R
I
K
V
K
A
S
G
G
I
R
D
L
E
T
A
I
S
M
I
E
A
G
A
D
R
I
G
T
S
---------
S
G
I
S
I
A
E
E
F
L
------
24
PsiBlast_CBE
91.82
50%
-84
- C2 -
3OA3
1
?
B:
[59-269]
------------
A
Q
I
I
D
H
T
Q
L
S
L
S
A
T
G
S
Q
I
D
V
L
C
A
E
A
K
E
Y
--
G
--
F
A
T
V
C
V
R
P
D
Y
V
S
R
A
V
Q
Y
L
Q
G
---
T
---
Q
V
G
V
T
C
V
I
G
F
H
E
G
T
Y
S
T
D
Q
K
V
S
E
A
K
R
A
M
Q
N
G
A
S
E
L
D
M
V
M
N
Y
P
W
L
S
E
K
R
----
Y
T
D
V
F
Q
D
I
R
A
V
R
L
A
A
K
--
D
A
I
L
K
V
I
L
E
T
----
S
Q
L
-
T
A
----
D
E
I
I
A
G
C
V
L
S
S
L
---
A
G
A
D
Y
V
K
T
S
T
G
F
-
N
G
-
P
G
A
S
I
E
N
V
S
L
M
S
AVC
D
S
-----
L
Q
---
S
-----
E
T
R
V
K
A
S
G
G
I
R
T
I
E
D
C
V
K
M
V
R
A
G
A
E
R
L
G
A
S
---------
A
G
V
K
I
V
----------
4
PsiBlast_PDB
91.57
50%
-88
- C2 -
3OA3
1
?
A:
[59-269]
------------
A
Q
I
I
D
H
T
Q
L
S
L
S
A
T
G
S
Q
I
D
V
L
C
A
E
A
K
E
Y
--
G
--
F
A
T
V
C
V
R
P
D
Y
V
S
R
A
V
Q
Y
L
Q
G
---
T
---
Q
V
G
V
T
C
V
I
G
F
H
E
G
T
Y
S
T
D
Q
K
V
S
E
A
K
R
A
M
Q
N
G
A
S
E
L
D
M
V
M
N
Y
P
W
L
S
E
K
R
----
Y
T
D
V
F
Q
D
I
R
A
V
R
L
A
A
K
--
D
A
I
L
K
V
I
L
E
T
----
S
Q
L
-
T
A
----
D
E
I
I
A
G
C
V
L
S
S
L
---
A
G
A
D
Y
V
K
T
S
T
G
F
-
N
G
-
P
G
A
S
I
E
N
V
S
L
M
S
A
V
C
D
S
-----
L
Q
---
S
-----
E
T
R
V
K
A
S
G
G
I
R
T
I
E
D
C
V
K
M
V
R
A
G
A
E
R
L
G
A
S
---------
A
G
V
K
I
V
----------
5
PsiBlast_PDB
88.42
42%
-82
- C2 -
1MZH
-
DEOC_AQUAE
A:
[6-211]
-------------
K
Y
I
D
N
A
A
L
K
P
H
L
S
E
K
E
I
E
E
F
V
L
K
S
E
E
L
--
G
--
I
Y
A
V
C
V
N
P
Y
H
V
K
L
A
S
S
--
I
A
---
K
---
K
V
K
V
C
C
V
I
G
F
P
L
G
L
N
K
T
S
V
K
V
K
E
A
V
E
A
V
R
D
G
A
Q
E
L
D
I
V
W
N
L
S
A
F
K
S
E
K
----
Y
D
F
V
V
E
E
L
K
E
I
F
R
E
T
P
--
S
A
V
H
K
V
I
V
E
T
----
P
Y
L
-
N
E
----
E
E
I
K
K
A
V
E
I
C
I
E
---
A
G
A
D
F
I
K
T
S
T
G
F
-
A
P
-
R
G
T
T
L
E
E
V
R
L
I
K
---
S
S
-----
A
K
---
G
-----
R
I
K
V
K
A
S
G
G
I
R
D
L
E
T
A
I
S
M
I
E
A
G
A
D
R
I
G
T
S
---------
S
G
I
S
I
A
E
---------
25
PsiBlast_CBE
87.84
42%
-81
- C2 -
1MZH
1
DEOC_AQUAE
B:
[6-211]
-------------
K
Y
I
D
N
A
A
L
K
P
H
L
S
E
K
E
I
E
E
F
V
L
K
S
E
E
L
--
G
--
I
Y
A
V
C
V
N
P
Y
H
V
K
L
A
S
S
--
I
A
---
K
---
K
V
K
V
C
C
V
I
G
F
P
L
G
L
N
K
T
S
V
K
V
K
E
A
V
E
A
V
R
D
G
A
Q
E
L
D
I
V
W
N
L
S
A
F
K
S
E
K
----
Y
D
F
V
V
E
E
L
K
E
I
F
R
E
T
P
--
S
A
V
H
K
V
I
V
E
T
----
P
Y
L
-
N
E
----
E
E
I
K
K
A
V
E
I
C
I
E
---
A
G
A
D
F
I
K
T
S
T
G
F
-
A
P
-
R
G
T
T
L
E
E
V
R
L
I
K
---
S
S
-----
A
K
---
G
-----
R
I
K
V
K
A
S
G
G
I
R
D
L
E
T
A
I
S
M
I
E
A
G
A
D
R
I
G
T
S
---------
S
G
I
S
I
A
E
---------
26
PsiBlast_CBE
87.19
39%
-78
- C2 -
1UB3
1
DEOC_THET8
D:
[2-212]
----------
D
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
--
F
Y
G
L
C
I
P
P
S
Y
V
A
W
V
R
A
R
Y
P
H
---
A
---
P
F
R
L
V
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
L
H
L
G
R
A
K
A
G
D
----
L
D
Y
L
E
A
E
V
R
A
V
R
E
A
V
P
--
Q
A
V
L
K
V
I
L
E
T
----
G
Y
F
-
S
P
----
E
E
I
A
R
L
A
E
A
A
I
R
---
G
G
A
D
F
L
K
T
S
T
G
F
-
G
P
-
R
G
A
S
L
E
D
V
A
L
L
V
---
R
V
-----
A
Q
---
G
-----
R
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
G
A
S
R
L
G
T
S
---------
S
G
V
A
L
V
A
---------
6
PsiBlast_PDB
86.62
39%
-76
- C2 -
1J2W
-
DEOC_THET8
A:
[1-212]
---------
M
D
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
--
F
Y
G
L
C
I
P
P
S
Y
V
A
W
V
R
A
R
Y
P
H
---
A
---
P
F
R
L
V
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
L
H
L
G
R
A
K
A
G
D
----
L
D
Y
L
E
A
E
V
R
A
V
R
E
A
V
P
--
Q
A
V
L
K
V
I
L
E
T
----
G
Y
F
-
S
P
----
E
E
I
A
R
L
A
E
A
A
I
R
---
G
G
A
D
F
L
K
T
S
T
G
F
-
G
P
-
R
G
A
S
L
E
D
V
A
L
L
V
---
R
V
-----
A
Q
---
G
-----
R
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
G
A
S
R
L
G
T
S
---------
S
G
V
A
L
V
A
---------
32
PsiBlast_CBE
86.55
43%
-77
- C2 -
3NG3
2
DEOC_MYCA1
B:
[13-226]
------------
A
A
F
V
D
H
T
L
L
K
P
E
A
T
A
A
D
V
A
A
L
V
T
E
A
A
E
L
--
G
--
V
Y
A
V
C
V
S
P
P
M
V
P
A
A
V
Q
--
A
----------
R
V
A
S
V
A
G
F
P
S
G
K
H
V
S
A
V
K
A
H
E
A
A
L
A
V
A
S
G
A
A
E
I
D
M
V
I
D
V
G
A
A
L
A
G
D
----
L
D
G
V
R
A
D
I
A
A
V
R
G
A
V
G
--
G
A
V
L
K
V
I
V
E
S
S
A
L
L
A
L
A
-
D
E
----
H
T
L
V
R
V
C
R
A
A
E
D
---
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
-
G
G
A
S
V
R
A
V
A
L
M
A
---
E
A
-----
V
G
---
G
-----
R
L
G
V
K
A
S
G
G
I
R
T
A
A
D
A
L
A
M
L
D
A
G
A
T
R
L
G
L
S
---------
G
T
R
A
V
L
D
G
L
-------
52
HHSearch
86.51
44%
-81
- C2 -
3NDO
4
?
A:
[11-230]
---------
A
Q
V
A
A
L
V
D
H
T
L
L
K
P
E
A
T
P
S
D
V
T
A
L
V
D
E
A
A
D
L
--
G
--
V
F
A
V
C
V
S
P
P
L
V
S
V
A
A
G
V
A
P
----
S
---
G
L
A
I
A
A
V
A
G
F
P
S
G
K
H
V
P
G
I
K
A
T
E
A
E
L
A
V
A
A
G
A
T
E
I
D
M
V
I
D
V
G
A
A
L
A
G
D
----
L
D
A
V
S
A
D
I
T
A
V
R
K
A
V
R
--
A
A
T
L
K
V
I
V
E
S
----
A
A
L
-
L
E
F
SG
E
P
L
L
A
D
V
C
R
V
A
R
D
---
A
G
A
D
F
V
K
T
S
T
G
F
-
H
P
S
G
G
A
S
V
Q
A
V
E
I
M
A
---
R
T
-----
V
G
---
E
-----
R
L
G
V
K
A
S
G
G
I
R
T
A
E
Q
A
A
A
M
L
D
A
G
A
T
R
L
G
L
S
---------
G
S
R
A
V
L
D
G
F
G
S
-----
31
PsiBlast_CBE
86.38
43%
-80
- C2 -
3NG3
4
DEOC_MYCA1
C:
[13-226]
------------
A
A
F
V
D
H
T
L
L
K
P
E
A
T
A
A
D
V
A
A
L
V
T
E
A
A
E
L
--
G
--
V
Y
A
V
C
V
S
P
P
M
V
P
A
A
V
Q
--
A
G
---
A
---
G
V
R
V
A
S
V
A
G
F
P
S
G
K
H
V
S
A
V
K
A
H
E
A
A
L
A
V
A
S
G
A
A
E
I
D
M
V
I
D
V
G
A
A
L
A
G
D
----
L
D
G
V
R
A
D
I
A
A
V
R
G
A
V
G
--
G
A
V
L
K
V
I
V
E
S
S
A
L
L
A
L
A
-
D
E
----
H
T
L
V
R
V
C
R
A
A
E
D
---
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
-
G
G
A
S
V
R
A
V
A
L
M
A
---
E
A
-----
V
G
---
G
-----
R
L
G
V
K
A
S
G
G
I
R
T
A
A
D
A
L
A
M
L
D
A
G
A
T
R
L
G
L
S
---------
G
T
R
A
V
L
D
G
L
-------
49
HHSearch
86.28
39%
-76
- C2 -
1UB3
1
DEOC_THET8
A:
[2-212]
----------
D
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
--
F
Y
G
L
C
I
P
P
S
Y
V
A
W
V
R
A
R
Y
P
H
---
A
---
P
F
R
L
V
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
L
H
L
G
R
A
K
A
G
D
----
L
D
Y
L
E
A
E
V
R
A
V
R
E
A
V
P
--
Q
A
V
L
K
V
I
L
E
T
----
G
Y
F
-
S
P
----
E
E
I
A
R
L
A
E
A
A
I
R
---
G
G
A
D
F
L
K
T
S
T
G
F
-
G
P
-
R
G
A
S
L
E
D
V
A
L
L
V
---
R
V
-----
A
Q
---
G
-----
R
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
G
A
S
R
L
G
T
S
---------
S
G
V
A
L
V
A
---------
7
PsiBlast_PDB
86.28
39%
-76
- C2 -
1UB3
1
DEOC_THET8
A:
[2-212]
----------
D
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
--
F
Y
G
L
C
I
P
P
S
Y
V
A
W
V
R
A
R
Y
P
H
---
A
---
P
F
R
L
V
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
L
H
L
G
R
A
K
A
G
D
----
L
D
Y
L
E
A
E
V
R
A
V
R
E
A
V
P
--
Q
A
V
L
K
V
I
L
E
T
----
G
Y
F
-
S
P
----
E
E
I
A
R
L
A
E
A
A
I
R
---
G
G
A
D
F
L
K
T
S
T
G
F
-
G
P
-
R
G
A
S
L
E
D
V
A
L
L
V
---
R
V
-----
A
Q
---
G
-----
R
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
G
A
S
R
L
G
T
S
---------
S
G
V
A
L
V
A
---------
9
PsiBlast_PDB
86.21
43%
-76
- C2 -
3NG3
2
DEOC_MYCA1
A:
[13-226]
------------
A
A
F
V
D
H
T
L
L
K
P
E
A
T
A
A
D
V
A
A
L
V
T
E
A
A
E
L
--
G
--
V
Y
A
V
C
V
S
P
P
M
V
P
A
A
V
Q
--
A
G
---
A
-----
R
V
A
S
V
A
G
F
P
S
G
K
H
V
S
A
V
K
A
H
E
A
A
L
A
V
A
S
G
A
A
E
I
D
M
V
I
D
V
G
A
A
L
A
G
D
----
L
D
G
V
R
A
D
I
A
A
V
R
G
A
V
G
--
G
A
V
L
K
V
I
V
E
S
S
A
L
L
A
L
A
-
D
E
----
H
T
L
V
R
V
C
R
A
A
E
D
---
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
-
G
G
A
S
V
R
A
V
A
L
M
A
---
E
A
-----
V
G
---
G
-----
R
L
G
V
K
A
S
G
G
I
R
T
A
A
D
A
L
A
M
L
D
A
G
A
T
R
L
G
L
S
---------
G
T
R
A
V
L
D
G
L
-------
30
PsiBlast_CBE
86.12
43%
-77
- C2 -
3NG3
2
DEOC_MYCA1
D:
[13-225]
------------
A
A
F
V
D
H
T
L
L
K
P
E
A
T
A
A
D
V
A
A
L
V
T
E
A
A
E
L
--
G
--
V
Y
A
V
C
V
S
P
P
M
V
P
A
A
V
Q
--
A
G
--------
V
R
V
A
S
V
A
G
F
P
S
G
K
H
V
S
A
V
K
A
H
E
A
A
L
A
V
A
S
G
A
A
E
I
D
M
V
I
D
V
G
A
A
L
A
G
D
----
L
D
G
V
R
A
D
I
A
A
V
R
G
A
V
G
--
G
A
V
L
K
V
I
V
E
S
SALL
A
L
A
-
D
E
----
H
T
L
V
R
V
C
R
A
A
E
D
---
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
-
G
G
A
S
V
R
A
V
A
L
M
A
---
E
A
-----
V
G
---
G
-----
R
L
G
V
K
A
S
G
G
I
R
T
A
A
D
A
L
A
M
L
D
A
G
A
T
R
L
G
L
S
---------
G
T
R
A
V
L
D
G
--------
28
PsiBlast_CBE
85.73
39%
-80
- C2 -
1UB3
1
DEOC_THET8
B:
[1-211]
---------
M
D
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
--
F
Y
G
L
C
I
P
P
S
Y
V
A
W
V
R
A
R
Y
P
H
---
A
---
P
F
R
L
V
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
L
H
L
G
R
A
K
A
G
D
----
L
D
Y
L
E
A
E
V
R
A
V
R
E
A
V
P
--
Q
A
V
L
K
V
I
L
E
T
----
G
Y
F
-
S
P
----
E
E
I
A
R
L
A
E
A
A
I
R
---
G
G
A
D
F
L
K
T
S
T
G
F
-
G
P
-
R
G
A
S
L
E
D
V
A
L
L
V
---
R
V
-----
A
Q
---
G
-----
R
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
G
A
S
R
L
G
T
S
---------
S
G
V
A
L
V
----------
27
PsiBlast_CBE
84.72
39%
-78
- C2 -
1UB3
1
DEOC_THET8
C:
[2-211]
----------
D
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
--
F
Y
G
L
C
I
P
P
S
Y
V
A
W
V
R
A
R
Y
P
H
---
A
---
P
F
R
L
V
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
L
H
L
G
R
A
K
A
G
D
----
L
D
Y
L
E
A
E
V
R
A
V
R
E
A
V
P
--
Q
A
V
L
K
V
I
L
E
T
----
G
Y
F
-
S
P
----
E
E
I
A
R
L
A
E
A
A
I
R
---
G
G
A
D
F
L
K
T
S
T
G
F
-
G
P
-
R
G
A
S
L
E
D
V
A
L
L
V
---
R
V
-----
A
Q
---
G
-----
R
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
G
A
S
R
L
G
T
S
---------
S
G
V
A
L
V
----------
29
PsiBlast_CBE
81.98
44%
-85
- C2 -
3NDO
3
?
B:
[14-228]
------------
A
A
L
V
D
H
T
L
L
K
P
E
A
T
P
S
D
V
T
A
L
V
D
E
A
A
D
L
--
G
--
V
F
A
V
C
V
S
P
P
L
V
S
V
A
A
G
-
V
A
P
---
S
---
G
L
A
I
A
A
V
A
G
F
P
S
G
K
H
V
P
G
I
K
A
T
E
A
E
L
A
V
A
A
G
A
T
E
I
D
M
V
I
D
V
G
A
A
L
A
G
D
----
L
D
A
V
S
A
D
I
T
A
V
R
K
A
V
R
--
A
A
T
L
K
V
I
V
E
S
A---
A
L
L
-
E
F
----
S
G
E
P
L
L
A
D
V
C
R
V
ARD
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
-
G
G
A
S
V
Q
A
V
E
I
M
A
---
R
T
-----
V
G
---
E
-----
R
L
G
V
K
A
S
G
G
I
R
T
A
E
Q
A
A
A
M
L
D
A
G
A
T
R
L
G
L
S
---------
G
S
R
A
V
L
D
G
F
-------
8
PsiBlast_PDB
81.81
44%
-84
- C2 -
3NDO
4
?
A:
[14-228]
------------
A
A
L
V
D
H
T
L
L
K
P
E
A
T
P
S
D
V
T
A
L
V
D
E
A
A
D
L
--
G
--
V
F
A
V
C
V
S
P
P
L
V
S
V
A
A
G
-
V
A
P
---
S
---
G
L
A
I
A
A
V
A
G
F
P
S
G
K
H
V
P
G
I
K
A
T
E
A
E
L
A
V
A
A
G
A
T
E
I
D
M
V
I
D
V
G
A
A
L
A
G
D
----
L
D
A
V
S
A
D
I
T
A
V
R
K
A
V
R
--
A
A
T
L
K
V
I
V
E
S
A
---
A
L
L
-
E
F
----
S
G
E
P
L
L
A
D
V
C
R
V
A
R
D
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
-
G
G
A
S
V
Q
A
V
E
I
M
A
---
R
T
-----
V
G
---
E
-----
R
L
G
V
K
A
S
G
G
I
R
T
A
E
Q
A
A
A
M
L
D
A
G
A
T
R
L
G
L
S
---------
G
S
R
A
V
L
D
G
F
-------
15
PsiBlast_PDB
76.32
34%
-69
- C2 -
1JCJ
1
DEOC_ECOLI
A:
[10-217]
---------
L
R
A
L
K
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
VG
N
--
T
A
A
I
C
I
Y
P
R
F
I
P
I
A
R
K
T
L
K
E
Q
GT
P
---
E
I
R
I
A
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
F
P
Y
R
A
L
M
A
G
N
E
Q
V
G
F
D
L
V
K
A
--
C
K
E
A
C
A
A
A
--
N
V
L
L
K
V
I
I
E
T
G---
E
L
K
-
D
E
----
A
L
I
R
K
A
S
E
I
S
I
K
---
A
G
A
D
F
I
K
T
S
T
G
K
-
V
A
-
V
N
A
T
P
E
S
A
R
I
M
M
---
E
V
I
R
D
M
G
V
E
---
K
-----
T
V
G
F
L
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
-----------------------------------
64
Fugue
75.56
32%
-75
- C2 -
1JCL
1
DEOC_ECOLI
A:
[1-252]
HMT
D
L
K
A
S
S
L
R
A
L
K
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
--
V
GN
T
A
A
I
C
I
Y
P
R
F
I
P
I
A
R
K
T
L
K
E
---
Q
GTP
E
I
R
I
A
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
F
P
Y
R
A
L
M
A
G
N
----
E
Q
V
G
F
D
L
V
K
A
C
K
E
A
C
A
A
A
N
V
L
L
K
V
I
I
E
T
----
G
E
L
K
D
E
----
A
L
I
R
K
A
S
E
I
S
I
K
---
A
G
A
D
F
I
K
T
S
T
G
K
-
V
A
-
V
N
A
T
P
E
S
A
R
I
M
M
---
E
V
-----
I
R
---
D
M
GVEK
T
V
G
F
K
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
A
I
A
D
E
L
F
G
A
D
WADARHYRF
G
A
S
S
L
L
A
S
L
L
K
A
L
G
H
G
13
PsiBlast_PDB
75.32
34%
-67
- C2 -
1JCL
1
DEOC_ECOLI
A:
[10-217]
---------
L
R
A
L
K
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
VG
N
--
T
A
A
I
C
I
Y
P
R
F
I
P
I
A
R
K
T
L
K
E
Q
GT
P
---
E
I
R
I
A
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
F
P
Y
R
A
L
M
A
G
N
E
Q
V
G
F
D
L
V
K
A
--
C
K
E
A
C
A
A
A
--
N
V
L
L
K
V
I
I
E
T
G---
E
L
K
-
D
E
----
A
L
I
R
K
A
S
E
I
S
I
K
---
A
G
A
D
F
I
K
T
S
T
G
K
-
V
A
-
V
N
A
T
P
E
S
A
R
I
M
M
---
E
V
I
R
D
M
G
V
E
---
K
-----
T
V
G
F
K
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
-----------------------------------
34
PsiBlast_CBE
75.10
34%
-66
- C2 -
1JCL
1
DEOC_ECOLI
B:
[10-217]
---------
L
R
A
L
K
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
VG
N
--
T
A
A
I
C
I
Y
P
R
F
I
P
I
A
R
K
T
L
K
E
QGT
P
---
E
I
R
I
A
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
F
P
Y
R
A
L
M
A
G
N
EQVG
F
D
L
V
K
A
--
C
K
E
A
C
A
A
A
--
N
V
L
L
K
V
I
I
E
T
G---
E
L
K
-
D
E
----
A
L
I
R
K
A
S
E
I
S
I
K
---
A
G
A
D
F
I
K
T
S
T
G
K
-
V
A
-
V
N
A
T
P
E
S
A
R
I
M
M
---
E
V
IRDMG
V
E
---
K
-----
T
V
G
F
K
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
-----------------------------------
35
PsiBlast_CBE
74.55
34%
-67
- C2 -
1JCJ
1
DEOC_ECOLI
B:
[10-217]
---------
L
R
A
L
K
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
VG
N
--
T
A
A
I
C
I
Y
P
R
F
I
P
I
A
R
K
T
L
K
E
QGT
P
---
E
I
R
I
A
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
F
P
Y
R
A
L
M
A
G
N
EQVG
F
D
L
V
K
A
--
C
K
E
A
C
A
A
A
--
N
V
L
L
K
V
I
I
E
T
G---
E
L
K
-
D
E
----
A
L
I
R
K
A
S
E
I
S
I
K
---
A
G
A
D
F
I
K
T
S
T
G
K
-
V
A
-
V
N
A
T
P
E
S
A
R
I
M
M
---
E
V
IRDMG
V
E
---
K
-----
T
V
G
F
L
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
-----------------------------------