@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1969: (2016-03-30 )
MLTVDQVKELVGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKLAMAQLGGAPQLDLQMAVVNALKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGIDEKPGIKGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVKWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160-..---.-----.----------.-..170..-.......180......-.-190....---------...200....------...210.....----..220.......230.......240.......250.......260.......--------270......----...280......-..290..---------.....300...---....310.......320....-.-..-330.......340.......350..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
ML
T
V
D
Q
V
K
E
L
V
G
E
IKDPIIDVPLKETE
G
I
V
E
V
S
IKEEKE
H
V
S
V
K
L
A
M
A
QLGGAP
Q
L
D
L
Q
M
A
V
V
N
A
L
K
ENG
A
K
T
V
G
I
R
F
ETL
P
E
E
K
V
N
QFKPKEENKP
K
T
I
E
G
L
LSQNN
P
V
E
F
I
A
I
ASGKGGVGK
S
T
V
A
V
N
L
A
V
A
L
AREG
K
K
V
G
L
V
D
ADIYGFSVPDMMGIDE-KP---G-----I----------K-GK
E
--
V
I
-
P
VERH
G
V
K
V
I
S
M
A
F
F
V-E-ENA
P
V
I
W
---------RG
P
M
L
G
K
M
L
T
------
N
F
F
T
EVKWG
D
I
----
E
Y
L
I
L
DLPPGTG
D
V
A
L
D
V
H
TMLPSSK
E
I
I
V
TTPHP
T
A
A
F
V
A
A
RAGAMAKHT
D
--------
H
--
S
I
L
G
V
I
----EN
M
S
-
Y
FESKET-GNK
E
Y
V
F
---------GKGGG
T
K
L
A
D
E
---
L
N
T
Q
L
L
G
ELPLEQPSW
N
P
K
DF-A-
P
S
-
I
YQSD
D
R
L
G
K
I
Y
S
S
I
A
Q
K
V
I
AATNK
1
PsiBlast_PDB
91.27
41%
-104
- C3 -
2PH1
1
?
A:
[21-230]
----------------------------------------------------------------------------------------------------------------
I
A
V
M
S
G
K
G
G
V
G
K
S
T
V
T
A
L
L
A
V
H
Y
A
R
Q
G
K
K
V
G
I
L
D
A
D
F
L
G
P
S
I
P
I
L
F
G
L
R
N
-
A
R
I
A
V
S
-----
A
----------
E
-
G
L
E
--
P
V
-
L
T
Q
K
Y
G
I
K
V
M
S
M
Q
F
L
L
P
K
-
E
N
T
P
V
I
W
---------
R
G
P
L
I
A
G
M
I
R
------
E
F
L
G
R
V
A
W
G
E
L
----
D
H
L
L
I
D
L
P
P
G
T
G
D
A
P
L
T
V
M
Q
D
A
K
P
T
G
V
V
V
V
S
T
P
Q
E
L
T
A
V
I
V
E
K
A
I
N
M
A
E
E
T
N
--------
T
--
S
V
L
G
L
V
----
E
N
M
S
-
Y
F
V
C
P
N
C
-
G
H
K
S
Y
I
F
---------
G
E
G
K
G
E
S
L
A
K
K
---
Y
N
I
G
F
F
T
S
I
P
I
E
E
---------------------------------------
143
HHSearch
89.75
40%
-79
- C3 -
2PH1
1
?
A:
[13-247]
--------------------------------------------------------------------------------------------------------
R
L
G
K
I
K
S
R
I
A
V
M
S
G
K
G
G
V
G
K
S
T
V
T
A
L
L
A
V
H
Y
A
R
Q
G
K
K
V
G
I
L
D
A
D
F
L
G
P
S
I
P
I
L
F
G
L
R
N
-
A
R
---
I
A
V
S
AE
G
----------
L
-
E
P
V
--
L
T
-
Q
--
K
Y
G
I
K
V
M
S
M
Q
F
L
L
-
P
K
E
N
T
P
V
I
W
---------
R
G
P
L
I
A
G
M
I
R
------
E
F
L
G
R
V
A
W
G
E
L
----
D
H
L
L
I
D
L
P
P
G
T
G
D
A
P
L
T
V
M
Q
D
A
K
P
T
G
V
V
V
V
S
T
P
Q
E
L
T
A
V
I
V
E
K
A
I
N
M
A
E
E
T
N
--------
T
--
S
V
L
G
L
V
----
E
N
M
S
-
Y
F
V
C
P
N
C
-
G
H
K
S
Y
I
F
---------
G
E
G
K
G
E
S
L
A
K
K
---
Y
N
I
G
F
F
T
S
I
P
I
E
E
E
L
I
K
L
A
D
S
G
R
-
I
E
E
Y
E
K
D
---------------------
2
PsiBlast_PDB
86.50
41%
-103
- C3 -
3KB1
3
?
A:
[21-229]
----------------------------------------------------------------------------------------------------------------
I
A
V
M
S
G
K
G
G
V
G
K
S
T
V
T
A
L
L
A
V
H
Y
A
K
Q
G
K
K
V
G
I
L
D
A
D
F
L
G
P
S
I
P
H
L
F
G
L
E
K
G
K
V
---
A
-----
V
S
D--------
E
-
G
L
E
--
P
V
-
L
T
Q
R
L
G
I
K
V
M
S
I
Q
F
L
L
----------------------
L
I
A
G
M
I
R
------
E
F
L
G
R
V
A
W
G
E
L
----
D
Y
L
L
I
D
L
P
P
G
T
G
D
A
P
L
T
V
M
Q
D
A
K
P
N
G
A
V
I
V
S
T
P
Q
E
L
T
A
A
V
V
E
K
A
I
T
M
A
E
Q
T
K
--------
T
--
A
V
L
G
I
V
----
E
N
M
A
-
Y
F
E
C
P
N
C
-
G
E
R
T
Y
L
F
---------
G
E
G
K
A
S
E
L
A
R
K
---
Y
K
I
E
F
I
T
E
I
P
I
D
----------------------------------------
4
PsiBlast_PDB
80.59
31%
-108
- C4 -
5AUN
4
?
B:
[1-218]
-------------------------------------------------------------------------------------
M
N
A
I
D
P
R
E
I
A
I
N
A
R
L
E
G
V
------
K
R
I
I
P
V
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
F
E
P
-
K
E
---
F
-----
P
----------
E
E
D
R
G
--
V
V
-
P
P
T
V
H
G
I
K
F
M
T
I
A
Y
Y
T
-
E
-
D
R
-
P
T
P
L
---------
R
G
K
E
I
S
D
A
L
I
------
E
L
L
T
I
T
R
W
D
E
L
----
D
Y
L
V
I
D
M
P
P
G
L
G
D
Q
L
L
D
V
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
L
L
K
E
E
G
--------
H
--
K
V
I
G
V
V
----
E
N
M
K
--
L
---------
K
D
V
---------------
E
K
L
A
E
E
---
F
G
V
P
Y
L
V
G
I
P
F
-----------------------------------------
25
PsiBlast_CBE
80.05
31%
-105
- C4 -
3VX3
6
?
B:
[4-218]
----------------------------------------------------------------------------------------
I
D
P
R
E
I
A
I
N
A
R
L
E
G
V
------
K
R
I
I
P
V
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
F
E
P
-
K
E
---
F
-----
P
----------
E
E
D
R
G
--
V
V
-
P
P
T
V
H
G
I
K
F
M
T
I
A
Y
Y
T
-------
T
P
L
---------
R
G
K
E
I
S
D
A
L
I
------
E
L
L
T
I
T
R
W
D
E
L
----
D
Y
L
V
I
D
M
P
P
G
L
G
D
Q
L
L
D
V
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
L
L
K
E
E
G
--------
H
--
K
V
I
G
V
V
----
E
N
M
K
--
L
R
-------
E
K
D
V
---------------
E
K
L
A
E
E
---
F
G
V
P
Y
L
V
G
I
P
F
-----------------------------------------
5
PsiBlast_PDB
79.71
31%
-104
- C4 -
5AUO
4
?
B:
[4-218]
----------------------------------------------------------------------------------------
I
D
P
R
E
I
A
I
N
A
R
L
E
G
V
------
K
R
I
I
P
V
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
F
E
P
-
K
E
---
F
-----
P
----------
E
E
D
R
G
--
V
V
-
P
P
T
V
H
G
I
K
F
M
T
I
A
Y
Y
T
-
E
-
D
R
-
P
T
P
L
---------
R
G
K
E
I
S
D
A
L
I
------
E
L
L
T
I
T
R
W
D
E
L
----
D
Y
L
V
I
D
M
P
P
G
L
G
D
Q
L
L
D
V
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
L
L
K
E
E
G
--------
H
--
K
V
I
G
V
V
----
E
N
M
K
--
L
---------
K
D
V
---------------
E
K
L
A
E
E
---
F
G
V
P
Y
L
V
G
I
P
F
-----------------------------------------
24
PsiBlast_CBE
79.26
31%
-106
- C4 -
5AUP
3
?
I:
[1-218]
-------------------------------------------------------------------------------------
M
N
A
I
D
P
R
E
I
A
I
N
A
R
L
E
G
V
------
K
R
I
I
P
V
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
F
E
P
-
K
E
---
F
-----
P
----------
E
E
D
R
G
--
V
V
-
P
P
T
V
H
G
I
K
F
M
T
I
A
Y
Y
T
-
E
-
D
R
-
P
T
P
L
---------
R
G
K
E
I
S
D
A
L
I
------
E
L
L
T
I
T
R
W
D
E
L
----
D
Y
L
V
I
D
M
P
P
G
L
G
D
Q
L
L
D
V
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
L
L
K
E
E
G
--------
H
--
K
V
I
G
V
V
----
E
N
M
K
--
L
R
--------
K
D
V
---------------
E
K
L
A
E
E
---
F
G
V
P
Y
L
V
G
I
P
F
-----------------------------------------
6
PsiBlast_PDB
78.67
31%
-106
- C4 -
5AUP
3
?
B:
[1-218]
-------------------------------------------------------------------------------------
M
N
A
I
D
P
R
E
I
A
I
N
A
R
L
E
G
V
------
K
R
I
I
P
V
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
F
E
P
-
K
E
---
F
-----
P
----------
E
E
D
R
G
--
V
V
-
P
P
T
V
H
G
I
K
F
M
T
I
A
Y
Y
T
-
E
-
D
R
-
P
T
P
L
---------
R
G
K
E
I
S
D
A
L
I
------
E
L
L
T
I
T
R
W
D
E
L
----
D
Y
L
V
I
D
M
P
P
G
L
G
D
Q
L
L
D
V
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
L
L
K
E
E
G
--------
H
--
K
V
I
G
V
V
----
E
N
M
K
--
L
---------
K
D
V
---------------
E
K
L
A
E
E
---
F
G
V
P
Y
L
V
G
I
P
F
-----------------------------------------
3
PsiBlast_PDB
78.60
31%
-102
- C4 -
3VX3
5
?
A:
[4-218]
----------------------------------------------------------------------------------------
I
D
P
R
E
I
A
I
N
A
R
L
E
G
V
------
K
R
I
I
P
V
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
F
E
P
-
K
E
---
F
-----
P
----------
E
E
D
R
G
--
V
V
-
P
P
T
V
H
G
I
K
F
M
T
I
A
Y
Y
T
-------
T
P
L
---------
R
G
K
E
I
S
D
A
L
I
------
E
L
L
T
I
T
R
W
D
E
L
----
D
Y
L
V
I
D
M
P
P
G
L
G
D
Q
L
L
D
V
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
L
L
K
E
E
G
--------
H
--
K
V
I
G
V
V
----
E
N
M
K
--
L
R
-------
E
K
D
V
---------------
E
K
L
A
E
E
---
F
G
V
P
Y
L
V
G
I
P
F
-----------------------------------------
7
PsiBlast_PDB
78.22
31%
-104
- C4 -
5AUQ
1
?
A:
[4-218]
----------------------------------------------------------------------------------------
I
D
P
R
E
I
A
I
N
A
R
L
E
G
V
------
K
R
I
I
P
V
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
F
E
P
-
K
E
---
F
-----
P
----------
E
E
D
R
G
--
V
V
-
P
P
T
V
H
G
I
K
F
M
T
I
A
Y
Y
T
---------
L
---------
R
G
K
E
I
S
D
A
L
I
------
E
L
L
T
I
T
R
W
D
E
L
----
D
Y
L
V
I
D
M
P
P
G
L
G
D
Q
L
L
D
V
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
L
L
K
E
E
G
--------
H
--
K
V
I
G
V
V
----
E
N
M
K
--
L
R
--------
K
D
V
---------------
E
K
L
A
E
E
---
F
G
V
P
Y
L
V
G
I
P
F
-----------------------------------------
22
PsiBlast_CBE
77.27
31%
-107
- C4 -
5AUQ
1
?
C:
[5-218]
-----------------------------------------------------------------------------------------
D
P
R
E
I
A
I
N
A
R
L
E
G
V
------
K
R
I
I
P
V
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
F
E
P
-
K
E
---
F
-----
P
----------
E
E
D
R
G
--
V
V
-
P
P
T
V
H
G
I
K
F
M
T
I
A
Y
Y
T
--------
P
L
---------
R
G
K
E
I
S
D
A
L
I
------
E
L
L
T
I
T
R
W
D
E
L
----
D
Y
L
V
I
D
M
P
P
G
L
G
D
Q
L
L
D
V
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
L
L
K
E
E
G
--------
H
--
K
V
I
G
V
V
----
E
N
M
K
--
L
----------
D
V
---------------
E
K
L
A
E
E
---
F
G
V
P
Y
L
V
G
I
P
F
-----------------------------------------
21
PsiBlast_CBE
76.59
31%
-106
- C4 -
5AUQ
1
?
D:
[5-218]
-----------------------------------------------------------------------------------------
D
P
R
E
I
A
I
N
A
R
L
E
G
V
------
K
R
I
I
P
V
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
F
E
P
-
K
E
---
F
-----
P
----------
E
E
D
R
G
--
V
V
-
P
P
T
V
H
G
I
K
F
M
T
I
A
Y
Y
T
--------
P
L
---------
R
G
K
E
I
S
D
A
L
I
------
E
L
L
T
I
T
R
W
D
E
L
----
D
Y
L
V
I
D
M
P
P
G
L
G
D
Q
L
L
D
V
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
L
L
K
E
E
G
--------
H
--
K
V
I
G
V
V
----
E
N
M
K
--
L
---------
K
D
V
---------------
E
K
L
A
E
E
---
F
G
V
P
Y
L
V
G
I
P
F
-----------------------------------------
23
PsiBlast_CBE
76.47
31%
-108
- C4 -
5AUQ
1
?
B:
[5-218]
-----------------------------------------------------------------------------------------
D
P
R
E
I
A
I
N
A
R
L
E
G
V
------
K
R
I
I
P
V
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
F
E
P
-
K
E
---
F
-----
P
--------------
G
--
V
V
-
P
P
T
V
H
G
I
K
F
M
T
I
A
Y
Y
T
--------
P
L
---------
R
G
K
E
I
S
D
A
L
I
------
E
L
L
T
I
T
R
W
D
E
L
----
D
Y
L
V
I
D
M
P
P
G
L
G
D
Q
L
L
D
V
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
L
L
K
E
E
G
--------
H
--
K
V
I
G
V
V
----
E
N
M
K
--
L
---------
K
D
V
---------------
E
K
L
A
E
E
---
F
G
V
P
Y
L
V
G
I
P
F
-----------------------------------------
139
HHSearch
73.81
24%
-79
- C3 -
1G3Q
2
?
A:
[2-236]
-------------------------------------------------------------------------------------------------------------
G
R
I
I
S
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
G
V
D
D
-
P
D
---
V
-----
T
L
H
D
V
L
A
GEAN
V
-
E
D
A
--
I
Y
-
M
T
Q
F
D
N
V
Y
V
L
P
G
A
V
D
W
-
E
--
H
--
V
L
------------
K
A
D
P
R
K
L
P
------
E
V
I
K
S
L
K
-
D
K
F
----
D
F
I
L
I
D
C
P
A
G
L
Q
L
D
A
M
S
--
A
M
L
S
G
E
E
A
L
L
V
T
N
P
E
I
S
C
L
T
D
T
M
K
V
G
I
V
L
K
K
A
G
--------
L
--
A
I
L
G
F
V
----
L
N
R
Y
-
G
R
S
D
R
D
-------
I
-------------
P
P
E
A
A
E
D
V
---
M
E
V
P
L
L
A
V
I
P
E
D
P
A
I
R
E
G
T
L
E
G
I
-
P
A
V
K
Y
K
P
E
S
K
G
A
K
A
F
V
K
L
A
E
E
I
E
K
L
---
164
Fugue
73.35
24%
-78
- C3 -
3K9G
12
?
A:
[26-267]
------------------------------------------------------------------------------------------------------------
K
P
K
I
I
T
I
A
S
I
K
G
G
V
G
K
S
T
S
A
I
I
L
A
T
L
L
S
K
-
N
N
K
V
L
L
I
D
M
D
T
Q
A
S
I
T
S
Y
F
Y
E
K
I
E
-
K
L
---
G
-----
I
----------
N
-
F
T
K
FN
I
Y
-
E
I
L
K
E
N
V
D
I
D
S
T
I
I
N
V
-
D
-
N
N
L
D
L
I
P
---------
S
Y
L
T
L
H
N
F
S
E
D
K
I
E
HK
D
F
L
L
K
T
S
L
G
T
L
YYKY
D
Y
I
V
I
D
T
N
P
S
L
D
--
V
T
L
K
N
A
L
L
C
S
D
Y
V
I
I
P
M
T
A
E
K
W
A
V
E
S
L
D
L
F
N
F
F
V
R
K
L
N
--------
L
F
L
P
I
F
L
I
I
T
RFK
K
N
R
T
-
H
K
T
L
F
E
I
L
K
T
K
D
R
F
L
---------
G
T
I
S
E
N
K
D
Y
I
K
---
E
Y
E
N
I
L
E
I
F
L
K
K
I
---------------------------------------
19
PsiBlast_PDB
72.62
21%
-82
- C3 -
3R9I
4
MIND_ECOLI
A:
[3-247]
--------------------------------------------------------------------------------------------------------------
R
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
-
R
V
---
V
-----
Y
----------
D
-
F
V
N
--
V
I
-----
Q
G
D
A
T
L
N
Q
A
L
I
K
-
D
-
K
R
T
E
N
L
Y
I
L
P
A
S
QTRD
K
D
A
L
T
R
E
G
V
A
------
K
V
L
D
D
L
K
A
M
D
F
----
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
--
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
----------
V
R
D
S
D
--------
R
---
I
L
G
I
L
----
A
S
K
S
R
R
A
E
N
G
E
E
-
P
I
K
E
H
L
L
LTRYN
P
G
R
V
S
R
G
D
M
L
S
M
E
D
V
L
E
I
L
R
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
-
G
E
P
V
-
I
L
D
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
-----
18
PsiBlast_PDB
72.39
21%
-77
- C3 -
3Q9L
3
MIND_ECOLI
A:
[3-247]
--------------------------------------------------------------------------------------------------------------
R
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
-
R
V
---
V
-----
Y
----------
D
-
F
V
N
--
V
I
-----
Q
G
D
A
T
L
N
Q
A
L
I
K
-
D
-
K
R
T
E
N
L
Y
I
L
P
A
S
QTRD
K
D
A
L
T
R
E
G
V
A
------
K
V
L
D
D
L
K
A
M
D
F
----
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
--
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
----------
V
R
D
S
D
--------
R
---
I
L
G
I
L
----
A
S
K
S
R
R
A
E
N
G
E
E
-
P
I
K
E
H
L
L
L
T
RYN
P
G
R
V
S
R
G
D
M
L
S
M
E
D
V
L
E
I
L
R
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
-
G
E
P
V
-
I
L
D
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
-----
141
HHSearch
71.86
24%
-80
- C3 -
1HYQ
-
?
A:
[2-233]
-------------------------------------------------------------------------------------------------------------
V
R
T
I
T
V
A
S
G
K
G
G
T
G
K
T
T
I
T
A
N
L
G
V
A
L
A
Q
L
G
H
D
V
T
I
V
D
A
D
I
T
M
A
N
L
E
L
I
L
G
M
E
G
-
L
P
---
V
T----
L
Q
N
V
L
A
GEAR-
I
-
D
E
A
--
I
Y
--
V
G
P
G
G
V
K
V
V
P
A
G
V
S
L
-
E
-
G
L
--------------
R
-
K
A
N
P
E
K
L
E
------
D
V
L
T
Q
I
M
-
E
S
T
----
D
I
L
L
L
D
A
P
A
G
L
E
R
S
A
V
I
A
I
A
A
--
A
Q
E
L
L
L
V
V
N
P
E
I
S
S
I
T
D
G
L
K
T
K
I
V
A
E
R
L
G
--------
T
--
K
V
L
G
V
V
----
V
N
R
I
-
T
T
L
G
I
E
--------------------
M
A
K
N
E
I
E
A
I
---
L
E
A
K
V
I
G
L
I
P
E
D
P
E
V
R
R
A
A
A
Y
G
K
-
P
V
V
L
R
S
P
N
S
P
A
A
R
A
I
V
E
L
A
N
Y
I
A
-----
20
PsiBlast_PDB
71.80
21%
-84
- C3 -
3R9J
2
MIND_ECOLI
A:
[3-247]
--------------------------------------------------------------------------------------------------------------
R
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
-
R
V
---
V
-----
Y
----------
D
-
F
V
N
--
V
I
-----
Q
G
D
A
T
L
N
Q
A
L
I
K
-
D
-
K
R
T
E
N
L
Y
I
L
P
A
S
QTRD
K
D
A
L
T
R
E
G
V
A
------
K
V
L
D
D
L
K
A
M
D
F
----
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
--
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
----------
V
R
D
S
D
--------
R
---
I
L
G
I
L
----
A
S
-------
G
E
E
-
P
I
K
E
H
L
L
L
T
RYN
P
G
R
V
S
R
G
D
M
L
S
M
E
D
V
L
E
I
L
R
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
-
G
E
P
V
-
I
L
D
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
-----
144
HHSearch
67.18
19%
-66
* C3 *
3Q9L
3
MIND_ECOLI
A:
[2-250]
-------------------------------------------------------------------------------------------------------------
A
R
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
-
R
V
---
V
YD---
F
V
N
V
I
Q
GDAT-
L
-
N
Q
A
--
L
I
K
D
K
R
T
E
N
L
Y
I
L
P
A
S
Q
T
R
-
D
-
K
D
----------------
A
L
T
R
E
G
V
A
------
K
V
L
D
D
L
K
A
M
D
F
----
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
--
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
R
D
S
D
R
I
L
G
I
L
A
S
K
S
R
R
A
E
N
GEE
P
--
I
K
E
H
L
L
----
L
T
R
Y
-
N
P
G
R
V
S
R
-
G
--
D
M
-------------
L
S
M
E
D
V
L
E
I
---
L
R
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
G
E
-
P
V
I
L
D
-
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
E
--