@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA2001: (2016-03-31 )
MNHIEISKDVKIPVLGFGVFQIPQEQTAEAVKEAIKAGYRHIDTAQSYLNETEVGQGIEASGIDRSELFITTKVWIENVNYEDTIKSIERSLQRLNLDYLDLVLIHQPYNDVYGSWRALEELKENGKIKAIGVSNFGVDRIVDLGIHNQIQPQVNQIEINPFHQQEEQVAALQQENVVVEAWAPFAEGKNQLFQNQLLQAIADKYNKSIAQVILRWLVERDIVVLAKSVNPERMAQNLDIFDFELTEEDKQQIATLEESNSQFFSHADPEMIKALTSRELDV
Atome Classification :
(44 SA)
.......-..10........20...---....-.-30........40........50....----...----.60-----..-......70........80........90........100....--...---110-------------------..---.-.------------------.....120.......130....---...140......--.150.......160.......170..----.....180......-----.-190------.---------........200.......210.......220.......230.......240.......250.....--..---260-.......270.......280
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MN
H
I
E
IS-KDVKI
P
V
L
G
F
G
V
FQI
P
Q
---
E
Q
T
A
-
E
-
A
V
K
E
A
I
K
A
G
YR
H
I
D
T
A
Q
S
Y
L
N
E
T
E
VG----QGI----EAS-----GI-DR
S
E
L
F
I
T
T
K
V
W
I
ENV
N
Y
E
D
T
I
K
S
I
E
R
S
L
Q
R
L
N
L
D
Y
L
D
L
V
L
I
H--Q
P
Y
---
N
---------------------
D
V
---
Y
-
G
------------------
S
W
R
A
L
E
E
L
K
ENG
K
I
K
A
I
GVSNF---GV
D
R
I
V
DLGIHN--QIQPQV
N
Q
I
E
INP
F
H
Q
Q
E
E
Q
V
A
A
L
Q
Q----E
N
V
V
V
E
A
WA
P
F
AEG-----
K
-
N
--------
Q
---------
L
F
Q
N
Q
L
L
Q
A
I
A
D
K
Y
N
K
S
I
A
Q
V
I
L
R
W
L
V
ERD
I
V
V
L
AKSV
N
P
E
R
M
AQNL
D
I
F
D
F
EL
T
E
E
D
K
Q
Q
I
A
T
L
E--ES---NSQ-FFSHA
D
P
E
M
I
K
A
L
T
SRELDV
1
PsiBlast_PDB
93.40
53%
-88
- C6 -
1VP5
1
?
A:
[18-295]
---
V
T
L
N
-
N
G
V
E
M
P
I
L
G
Y
G
V
F
Q
I
P
P
---
E
K
T
E
-
E
-
C
V
Y
E
A
I
K
V
G
Y
R
L
I
D
T
A
A
S
Y
M
N
E
E
G
V
G
----
R
A
I
----
K
R
A
I
D
E
--
G
I
V
R
R
E
E
L
F
V
T
T
K
L
W
V
S
D
V
G
Y
E
S
T
K
K
A
F
E
K
S
L
K
K
L
Q
L
E
Y
I
D
L
Y
L
I
H
--
Q
P
F
---
G
---------------------
D
V
---
H
-
C
------------------
A
W
K
A
M
E
E
M
Y
K
D
G
L
V
R
A
I
G
V
S
N
F
---
Y
P
D
R
L
M
D
L
M
V
H
H
--
E
I
V
P
A
V
N
Q
I
E
I
H
P
F
Y
Q
R
Q
E
E
I
E
F
M
R
N
----
Y
N
I
Q
P
E
A
W
G
P
F
A
E
G
-----
R
-
K
--------
N
---------
I
F
Q
N
G
V
L
R
S
I
A
E
K
Y
G
K
T
V
A
Q
V
I
L
R
W
L
T
Q
K
G
I
V
A
I
P
K
T
V
R
R
E
R
M
K
E
N
I
S
I
F
D
F
E
L
T
Q
E
D
M
E
K
I
A
T
L
D
--
E
G
---
Q
S
A
-
F
F
S
H
R
D
P
E
V
V
K
W
I
C
S
-----
21
PsiBlast_CBE
93.39
53%
-89
- C6 -
1VP5
1
?
B:
[18-295]
---
V
T
L
N
-
N
G
V
E
M
P
I
L
G
Y
G
V
F
Q
I
P
P
---
E
K
T
E
-
E
-
C
V
Y
E
A
I
K
V
G
Y
R
L
I
D
T
A
A
S
Y
M
N
E
E
G
V
G
----
R
A
I
----
K
R
A
IDE--
G
I
V
R
R
E
E
L
F
V
T
T
K
L
W
V
S
D
V
G
Y
E
S
T
K
K
A
F
E
K
S
L
K
K
L
Q
L
E
Y
I
D
L
Y
L
I
H
--
Q
P
F
---
G
---------------------
D
V
---
H
-
C
------------------
A
W
K
A
M
E
E
M
Y
K
D
G
L
V
R
A
I
G
V
S
N
F
---
Y
P
D
R
L
M
D
L
M
V
H
H
--
E
I
V
P
A
V
N
Q
I
E
I
H
P
F
Y
Q
R
Q
E
E
I
E
F
M
R
N
----
Y
N
I
Q
P
E
A
W
G
P
F
A
E
G
-----
R
-
K
--------
N
---------
I
F
Q
N
G
V
L
R
S
I
A
E
K
Y
G
K
T
V
A
Q
V
I
L
R
W
L
T
Q
K
G
I
V
A
I
P
K
T
V
R
R
E
R
M
K
E
N
I
S
I
F
D
F
E
L
T
Q
E
D
M
E
K
I
A
T
L
D
--
E
G
---
Q
S
A
-
F
F
S
H
R
D
P
E
V
V
K
W
I
C
S
-----
2
PsiBlast_PDB
93.05
55%
-83
- C6 -
4MHB
8
?
A:
[18-297]
---
V
K
L
N
-
N
G
I
A
M
P
L
L
G
F
G
V
F
Q
M
T
N
---
T
A
E
C
-
E
R
A
V
I
D
A
I
E
T
G
Y
R
L
I
D
T
A
A
S
Y
Q
N
E
T
Q
V
G
----
N
A
L
----
K
L
S
-----
G
I
-
A
R
D
E
L
F
I
T
T
K
L
W
L
Q
D
T
Y
Y
E
G
A
K
A
Q
F
E
R
S
L
N
R
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
Q
P
Y
---
G
---------------------
D
V
---
H
-
G
------------------
A
W
R
A
M
E
E
L
H
Q
A
G
K
I
R
A
I
G
V
S
N
F
---
H
P
D
R
L
A
D
L
M
A
F
N
--
K
I
I
P
A
V
N
Q
I
E
V
N
P
F
N
Q
Q
L
H
A
V
P
W
M
Q
S
----
R
G
I
Q
P
E
A
W
A
P
F
A
E
G
-----
R
-
N
--------
G
---------
L
F
Q
N
P
V
L
T
A
I
G
E
K
Y
G
K
S
V
G
Q
V
V
L
R
W
I
F
Q
R
G
I
V
S
L
A
K
S
V
R
K
G
R
M
E
E
N
I
N
I
L
D
F
E
L
S
A
E
D
M
L
Q
I
A
A
L
D
--
T
A
---
T
S
A
-
F
F
S
H
R
D
P
A
M
V
E
W
L
T
G
R
K
L
D
V
101
HHSearch
92.35
53%
-81
- C6 -
1VP5
1
?
A:
[17-297]
---
K
V
T
L
N
N
G
V
E
M
P
I
L
G
Y
G
V
F
Q
I
P
P
---
E
K
T
E
-
E
-
C
V
Y
E
A
I
K
V
G
Y
R
L
I
D
T
A
A
S
Y
M
N
E
E
G
V
G
----
R
A
I
----
K
R
A
I
D
E
G-
I
V
-
R
R
E
E
L
F
V
T
T
K
L
W
V
S
D
V
G
Y
E
S
T
K
K
A
F
E
K
S
L
K
K
L
Q
L
E
Y
I
D
L
Y
L
I
H
--
Q
P
F
---
G
---------------------
D
V
---
H
-
C
------------------
A
W
K
A
M
E
E
M
Y
K
D
G
L
V
R
A
I
G
V
S
N
F
---
Y
P
D
R
L
M
D
L
M
V
H
H
--
E
I
V
P
A
V
N
Q
I
E
I
H
P
F
Y
Q
R
Q
E
E
I
E
F
M
R
N
----
Y
N
I
Q
P
E
A
W
G
P
F
A
E
G
-----
R
-
K
--------
N
---------
I
F
Q
N
G
V
L
R
S
I
A
E
K
Y
G
K
T
V
A
Q
V
I
L
R
W
L
T
Q
K
G
I
V
A
I
P
K
T
V
R
R
E
R
M
K
E
N
I
S
I
F
D
F
E
L
T
Q
E
D
M
E
K
I
A
T
L
D
--
E
G
----
Q
S
A
F
F
S
H
R
D
P
E
V
V
K
W
I
C
S
L
K
---
23
PsiBlast_CBE
90.18
44%
-92
- C6 -
4F40
10
PGFS_LEIMA
B:
[13-284]
---
V
T
L
S
-
N
G
V
K
M
P
Q
F
G
L
G
V
W
Q
S
P
A
G--
E
V
T
E
-
N
-
A
V
K
W
A
L
C
A
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
V
G
----
A
G
L
----
R
A
S
-----
G
V
-
P
R
E
D
V
F
I
T
T
K
L
W
N
T
E
Q
G
Y
E
S
T
L
A
A
F
E
E
S
R
Q
K
L
G
V
D
Y
I
D
L
Y
L
I
H
--
W
P
R
---
G
K--------------------
D
I
---
L
-
S
KEGKKYLD----------
S
W
R
A
F
E
Q
L
Y
K
E
K
K
V
R
A
I
G
V
S
N
F
---
H
I
H
H
L
E
D
V
L
A
M
C
--
T
V
T
P
M
V
N
Q
V
E
L
H
P
L
N
N
Q
A
D
L
R
A
F
C
D
A
----
K
Q
I
K
V
E
A
W
S
P
L
G
-------
K
--------------------
L
L
S
N
P
I
L
S
A
I
G
A
K
Y
N
K
T
A
A
Q
V
I
L
R
W
N
I
Q
K
N
L
I
T
I
P
K
S
V
H
R
E
R
I
E
E
N
A
D
I
F
D
F
E
L
G
A
E
D
V
M
S
I
D
A
L
---
N
T
---
N
S
R
-
Y
G
P
D
P
D
--------------
3
PsiBlast_PDB
89.51
44%
-92
- C6 -
4F40
11
PGFS_LEIMA
A:
[13-284]
---
V
T
L
S
-
N
G
V
K
M
P
Q
F
G
L
G
V
W
Q
S
P
A
G--
E
V
T
E
-
N
-
A
V
K
W
A
L
C
A
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
V
G
----
A
G
L
----
R
A
S
-----
G
V
-
P
R
E
D
V
F
I
T
T
K
L
W
N
T
E
Q
G
Y
E
S
T
L
A
A
F
E
E
S
R
Q
K
L
G
V
D
Y
I
D
L
Y
L
I
H
--
W
P
R
---
G
K
--------------------
D
I
---
L
-
S
K
EGKK
Y
L
D
----------
S
W
R
A
F
E
Q
L
Y
K
E
K
K
V
R
A
I
G
V
S
N
F
---
H
I
H
H
L
E
D
V
L
A
M
C
--
T
V
T
P
M
V
N
Q
V
E
L
H
P
L
N
N
Q
A
D
L
R
A
F
C
D
A
----
K
Q
I
K
V
E
A
W
S
P
L
G
-------
K
--------------------
L
L
S
N
P
I
L
S
A
I
G
A
K
Y
N
K
T
A
A
Q
V
I
L
R
W
N
I
Q
K
N
L
I
T
I
P
K
S
V
H
R
E
R
I
E
E
N
A
D
I
F
D
F
E
L
G
A
E
D
V
M
S
I
D
A
L
---
N
T
---
N
S
R
-
Y
G
P
D
P
D
--------------
22
PsiBlast_CBE
89.09
44%
-89
- C6 -
4G5D
1
PGFS_LEIMA
B:
[13-284]
---
V
T
L
S
-
N
G
V
K
M
P
Q
F
G
L
G
V
W
Q
S
P
A
G--
E
V
T
E
-
N
-
A
V
K
W
A
L
C
A
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
V
G
----
A
G
L
----
R
A
S
-----
G
V
-
P
R
E
D
V
F
I
T
T
K
L
W
N
T
E
Q
G
Y
E
S
T
L
A
A
F
E
E
S
R
Q
K
L
G
V
D
Y
I
D
L
Y
L
I
H
--
W
P
R
---
G
K
--------------------
D
I
---
L
-
S
K
EGKK
Y
L
D
----------
S
W
R
A
F
E
Q
L
Y
K
E
K
K
V
R
A
I
G
V
S
N
F
---
H
I
H
H
L
E
D
V
L
A
M
C
--
T
V
T
P
M
V
N
Q
V
E
L
H
P
L
N
N
Q
A
D
L
R
A
F
C
D
A
----
K
Q
I
K
V
E
A
W
S
P
L
G
Q
G
-----
K
--------------------
L
L
S
N
P
I
L
S
A
I
G
A
K
Y
N
K
T
A
A
Q
V
I
L
R
W
N
I
Q
K
N
L
I
T
I
P
K
S
V
H
R
E
R
I
E
E
N
A
D
I
F
D
F
E
L
G
A
E
D
V
M
S
I
D
A
L
---
N
T
---
N
S
R
-
Y
G
P
D
P
D
--------------
4
PsiBlast_PDB
88.84
44%
-91
- C6 -
4G5D
1
PGFS_LEIMA
A:
[13-284]
---
V
T
L
S
-
N
G
V
K
M
P
Q
F
G
L
G
V
W
Q
S
P
A
G--
E
V
T
E
-
N
-
A
V
K
W
A
L
C
A
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
V
G
----
A
G
L
----
R
A
S
-----
G
V
-
P
R
E
D
V
F
I
T
T
K
L
W
N
T
E
Q
G
Y
E
S
T
L
A
A
F
E
E
S
R
Q
K
L
G
V
D
Y
I
D
L
Y
L
I
H
--
W
P
R
---
G
K
--------------------
D
I
---
L
-
S
K
EGKK
Y
L
D
----------
S
W
R
A
F
E
Q
L
Y
K
E
K
K
V
R
A
I
G
V
S
N
F
---
H
I
H
H
L
E
D
V
L
A
M
C
--
T
V
T
P
M
V
N
Q
V
E
L
H
P
L
N
N
Q
A
D
L
R
A
F
C
D
A
----
K
Q
I
K
V
E
A
W
S
P
L
G
Q
G
-----
K
--------------------
L
L
S
N
P
I
L
S
A
I
G
A
K
Y
N
K
T
A
A
Q
V
I
L
R
W
N
I
Q
K
N
L
I
T
I
P
K
S
V
H
R
E
R
I
E
E
N
A
D
I
F
D
F
E
L
G
A
E
D
V
M
S
I
D
A
L
---
N
T
---
N
S
R
-
Y
G
P
D
P
D
--------------
6
PsiBlast_PDB
88.83
43%
-90
- C6 -
4FZI
1
PGFS_TRYCC
A:
[14-273]
-
N
C
V
T
L
H
-
N
S
V
R
M
P
Q
L
G
L
G
V
W
R
A
Q
D
G--
A
E
T
A
-
N
-
A
V
R
W
A
I
E
A
G
Y
R
H
I
D
T
A
Y
I
Y
S
N
E
R
G
V
G
----
Q
G
I
----
R
E
S
-----
G
V
-
P
R
E
E
V
W
V
T
T
K
V
W
N
S
D
Q
G
Y
E
K
T
L
A
A
F
E
R
S
R
E
L
L
G
L
E
Y
I
D
L
Y
L
I
H
--
W
P
G
---
K
---------------------
K
K
---
F
V
D
------------------
T
W
K
A
L
E
K
L
Y
E
E
K
K
V
R
A
I
G
V
S
N
F
---
E
P
H
H
L
T
E
L
F
K
S
C
--
K
I
R
P
M
V
N
Q
V
E
L
H
P
L
F
Q
Q
R
T
L
R
E
F
C
K
Q
----
H
N
I
A
I
T
A
W
S
P
L
G
S
G
-----
E
-
E
--------
A
G--------
I
L
K
N
H
V
L
G
E
I
A
K
K
H
N
K
S
P
A
Q
V
V
I
R
W
D
I
Q
H
G
I
V
T
I
P
K
S
T
N
K
G
R
I
Q
E
N
F
N
V
W
D
F
K
L
T
E
E
E
M
R
Q
I
D
E
L
N
--
E
----------------------------
7
PsiBlast_PDB
88.78
43%
-93
- C6 -
4GIE
2
PGFS_TRYCC
A:
[14-273]
-
N
C
V
T
L
H
-
N
S
V
R
M
P
Q
L
G
L
G
V
W
R
A
Q
D
G--
A
E
T
A
-
N
-
A
V
R
W
A
I
E
A
G
Y
R
H
I
D
T
A
Y
I
Y
S
N
E
R
G
V
G
----
Q
G
I
----
R
E
S
-----
G
V
-
P
R
E
E
V
W
V
T
T
K
V
W
N
S
D
Q
G
Y
E
K
T
L
A
A
F
E
R
S
R
E
L
L
G
L
E
Y
I
D
L
Y
L
I
H
--
W
P
G
---
K
---------------------
K
K
---
F
V
D
------------------
T
W
K
A
L
E
K
L
Y
E
E
K
K
V
R
A
I
G
V
S
N
F
---
E
P
H
H
L
T
E
L
F
K
S
C
--
K
I
R
P
M
V
N
Q
V
E
L
H
P
L
F
Q
Q
R
T
L
R
E
F
C
K
Q
----
H
N
I
A
I
T
A
W
S
P
L
G
S
G
-----
E
-
E
--------
A
G--------
I
L
K
N
H
V
L
G
E
I
A
K
K
H
N
K
S
P
A
Q
V
V
I
R
W
D
I
Q
H
G
I
V
T
I
P
K
S
T
N
K
G
R
I
Q
E
N
F
N
V
W
D
F
K
L
T
E
E
E
M
R
Q
I
D
E
L
N
--
E
----------------------------
36
PsiBlast_CBE
86.98
45%
-93
- C6 -
3B3D
1
YTBE_BACSU
C:
[45-302]
-----
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
Q
V
E
E
G--
S
E
L
V
-
N
-
A
V
K
T
A
I
V
H
G
Y
R
S
I
D
T
A
A
I
Y
G
N
E
A
G
V
G
----
E
G
I
REGI
E
E
A
-----
G
I
-
S
R
E
D
L
F
I
T
S
K
V
W
N
A
D
L
G
Y
E
E
T
L
A
A
F
E
T
S
L
S
K
L
G
L
D
Y
L
D
L
Y
L
I
H
--
W
P
V
---
E
---------------------
G
K
---
Y
-
K
E-----------------
A
W
R
A
L
E
T
L
Y
K
E
G
R
I
K
A
I
G
V
S
N
F
---
Q
I
H
H
L
E
D
L
M
T
A
A
--
E
I
K
P
M
I
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
I
R
Y
C
Q
N
----
Q
G
I
Q
M
E
A
W
S
P
L
M
Q
G
----------------
Q
---------
L
L
D
H
P
V
L
A
D
I
A
Q
T
Y
N
K
S
V
A
Q
I
I
L
R
W
D
L
Q
H
G
I
I
T
I
P
K
S
T
K
E
H
R
I
K
E
N
A
S
V
F
D
F
E
L
T
Q
D
D
M
N
R
I
D
A
L
N
--
E
N
---------------------------
105
HHSearch
86.67
44%
-95
- C6 -
3O0K
4
?
A:
[26-282]
V
P
T
V
K
L
N
-
D
G
N
H
I
P
Q
L
G
Y
G
V
W
Q
I
S
N
---
D
E
A
V
-
S
-
A
V
S
E
A
L
K
A
G
Y
R
H
I
D
T
A
T
I
Y
G
N
E
E
G
V
G
----
K
A
I
----
N
G
S
-----
G
I
-
A
R
A
D
I
F
L
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
K
A
F
D
T
S
L
K
K
L
G
T
D
Y
V
D
L
Y
L
I
H
--
W
P
M
---
P
S
K
D
------------------
L
F
---
M
-
E
------------------
T
W
R
A
F
I
K
L
K
E
E
G
R
V
K
S
I
G
V
S
N
F
---
R
T
A
D
L
E
R
L
I
K
E
S
--
G
V
T
P
V
L
N
Q
I
E
L
H
P
Q
F
Q
Q
D
E
L
R
L
F
H
G
K
----
H
D
I
A
T
E
A
W
S
P
L
G
Q
G
--------------------------
L
L
E
D
P
T
L
K
S
I
A
E
K
H
A
K
S
V
A
Q
I
I
L
R
W
H
I
E
T
G
N
I
V
I
P
K
S
I
T
P
A
R
I
K
E
N
F
D
I
F
D
F
T
L
N
G
T
D
H
D
A
I
T
K
L
--------------------------------
27
PsiBlast_CBE
86.57
43%
-91
- C6 -
4FZI
2
PGFS_TRYCC
B:
[14-273]
-
N
C
V
T
L
H
-
N
S
V
R
M
P
Q
L
G
L
G
V
W
R
A
Q
D
G--
A
E
T
A
-
N
-
A
V
R
W
A
I
E
A
G
Y
R
H
I
D
T
A
Y
I
Y
S
N
E
R
G
V
G
----
Q
G
I
----
R
E
S
-----
G
V
-
P
R
E
E
V
W
V
T
T
K
V
W
N
S
D
Q
G
Y
E
K
T
L
A
A
F
E
R
S
R
E
L
L
G
L
E
Y
I
D
L
Y
L
I
H
--
W
P
G
---
K
---------------------
K
K
---
F
V
D
------------------
T
W
K
A
L
E
K
L
Y
E
E
K
K
V
R
A
I
G
V
S
N
F
---
E
P
H
H
L
T
E
L
F
K
S
C
--
K
I
R
P
M
V
N
Q
V
E
L
H
P
L
F
Q
Q
R
T
L
R
E
F
C
K
Q
----
H
N
I
A
I
T
A
W
S
P
L
G
S
---------------------------
I
L
K
N
H
V
L
G
E
I
A
K
K
H
N
K
S
P
A
Q
V
V
I
R
W
D
I
Q
H
G
I
V
T
I
P
K
S
T
N
K
G
R
I
Q
E
N
F
N
V
W
D
F
K
L
T
E
E
E
M
R
Q
I
D
E
L
N
--
E
----------------------------
37
PsiBlast_CBE
86.07
45%
-97
- C6 -
3B3D
1
YTBE_BACSU
B:
[45-302]
-----
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
Q
V
E
E
G--
S
E
L
V
-
N
-
A
V
K
T
A
I
V
H
G
Y
R
S
I
D
T
A
A
I
Y
G
N
E
A
G
V
G
----
E
G
I
R
E
G
I
E
E
A
-----
G
I
-
S
R
E
D
L
F
I
T
S
K
V
W
N
A
D
L
G
Y
E
E
T
L
A
A
F
E
T
S
L
S
K
L
G
L
D
Y
L
D
L
Y
L
I
H
--
W
P
V
---
E
---------------------
G
K
---
Y
-
K
E
-----------------
A
W
R
A
L
E
T
L
Y
K
E
G
R
I
K
A
I
G
V
S
N
F
---
Q
I
H
H
L
E
D
L
M
T
A
A
--
E
I
K
P
M
I
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
I
R
Y
C
Q
N
----
Q
G
I
Q
M
E
A
W
S
P
L
M
Q
G
----------------
Q
---------
L
L
D
H
P
V
L
A
D
I
A
Q
T
Y
N
K
S
V
A
Q
I
I
L
R
W
D
L
Q
H
G
I
I
T
I
P
K
S
T
K
E
H
R
I
K
E
N
A
S
V
F
D
F
E
L
T
Q
D
D
M
N
R
I
D
A
L
N
--
E
N
---------------------------
112
HHSearch
85.46
46%
-87
- C6 -
3F7J
7
GR_BACSU
A:
[6-270]
K
D
T
V
K
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
K
V
E
N
G--
N
E
A
T
-
E
-
S
V
K
A
A
I
K
N
G
Y
R
S
I
D
T
A
A
I
Y
K
N
E
E
G
V
G
----
I
G
I
----
K
E
S
-----
G
V
-
A
R
E
E
L
F
I
T
S
K
V
W
N
E
D
Q
G
Y
E
T
T
L
A
A
F
E
K
S
L
E
R
L
Q
L
D
Y
L
D
L
Y
L
I
H
--
W
P
G
---
K
D--------------------
K
Y
---
K
-
D
------------------
T
W
R
A
L
E
K
L
Y
K
D
G
K
I
R
A
I
G
V
S
N
F
---
Q
V
H
H
L
E
E
L
L
K
D
A
--
E
I
K
P
M
V
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
R
D
Y
C
K
G
----
Q
G
I
Q
L
E
A
W
S
P
L
M
Q
G
-----
Q
--------------------
L
L
D
N
E
V
L
T
Q
I
A
E
K
H
N
K
S
V
A
Q
V
I
L
R
W
D
L
Q
H
G
V
V
T
I
P
K
S
I
K
E
H
R
I
I
E
N
A
D
I
F
D
F
E
L
S
Q
E
D
M
D
K
I
D
A
L
N
--
K
D
---
E
R
V
-
G
P
N
-----------------
35
PsiBlast_CBE
84.97
48%
-99
- C6 -
3D3F
1
GR_BACSU
B:
[8-260]
---
V
K
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
K
V
E
N
---
G
N
E
A
T
E
-
S
V
K
A
A
I
K
N
G
Y
R
S
I
D
T
A
A
I
Y
K
N
E
E
G
V
G
----
I
G
I
----
K
E
S
-----
G
V
-
A
R
E
E
L
F
I
T
S
K
V
W
N
E
D
Q
G
Y
E
T
T
L
A
A
F
E
K
S
L
E
R
L
Q
L
D
Y
L
D
L
Y
L
I
H
--
W
P
G
---
K
---------------------
D
K
---
Y
K
D
------------------
T
W
R
A
L
E
K
L
Y
K
D
G
K
I
R
A
I
G
V
S
N
F
---
Q
V
H
H
L
E
E
L
L
K
D
A
--
E
I
K
P
M
V
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
R
D
Y
C
K
G
----
Q
G
I
Q
L
E
A
W
S
P
L
M
Q
G
----------------
Q
---------
L
L
D
N
E
V
L
T
Q
I
A
E
K
H
N
K
S
V
A
Q
V
I
L
R
W
D
L
Q
H
G
V
V
T
I
P
K
S
I
K
E
H
R
I
I
E
N
A
D
I
F
D
F
E
L
S
Q
E
D
M
D
K
I
D
A
L
--------------------------------
31
PsiBlast_CBE
84.90
41%
-91
- C6 -
4Q3M
1
?
D:
[2-266]
-
H
S
V
K
L
N
-
N
N
Y
E
M
P
I
I
G
L
G
T
F
R
S
K
K
---
N
D
A
Y
-
N
-
A
V
K
A
A
L
E
G
G
Y
R
H
I
D
T
A
M
I
Y
G
N
E
E
E
V
G
----
R
A
I
----
K
D
S
-----
N
I
-
P
R
E
E
I
F
V
T
T
K
L
W
N
T
D
Q
G
Y
E
K
T
L
E
A
F
N
T
S
L
K
N
L
G
L
D
Y
I
D
L
Y
L
I
H
WF
K
G
Y
---
D
---------------------
N
A
---
L
-
S
------------------
T
Y
R
A
F
E
T
L
Y
E
E
G
K
V
K
A
I
G
V
S
N
F
---
N
V
H
H
L
M
Y
L
M
E
N
A
--
K
I
P
P
M
V
N
Q
V
E
T
H
V
T
L
Q
N
H
F
L
H
D
Y
C
K
K
----
N
N
I
Q
L
E
A
Y
A
P
L
M
S
H
-----
Q
I
K
--------
D
---------
L
L
S
N
E
T
M
A
K
I
A
K
K
H
D
K
T
I
P
Q
I
A
I
R
W
L
I
E
R
E
I
V
V
I
P
K
S
I
T
P
E
R
I
V
Q
N
F
D
V
F
D
F
T
L
D
E
E
D
M
K
S
I
R
S
V
N
--
T
G
---
K
K
I
-
F
-------------------
10
PsiBlast_PDB
84.68
48%
-94
- C6 -
3F7J
6
GR_BACSU
A:
[9-261]
---
V
K
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
K
V
E
N
---
G
N
E
A
T
E
-
S
V
K
A
A
I
K
N
G
Y
R
S
I
D
T
A
A
I
Y
K
N
E
E
G
V
G
----
I
G
I
----
K
E
S
-----
G
V
-
A
R
E
E
L
F
I
T
S
K
V
W
N
E
D
Q
G
Y
E
T
T
L
A
A
F
E
K
S
L
E
R
L
Q
L
D
Y
L
D
L
Y
L
I
H
--
W
P
G
---
K
---------------------
D
K
---
Y
K
D
------------------
T
W
R
A
L
E
K
L
Y
K
D
G
K
I
R
A
I
G
V
S
N
F
---
Q
V
H
H
L
E
E
L
L
K
D
A
--
E
I
K
P
M
V
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
R
D
Y
C
K
G
----
Q
G
I
Q
L
E
A
W
S
P
L
M
Q
G
----------------
Q
---------
L
L
D
N
E
V
L
T
Q
I
A
E
K
H
N
K
S
V
A
Q
V
I
L
R
W
D
L
Q
H
G
V
V
T
I
P
K
S
I
K
E
H
R
I
I
E
N
A
D
I
F
D
F
E
L
S
Q
E
D
M
D
K
I
D
A
L
--------------------------------
12
PsiBlast_PDB
84.58
45%
-92
- C6 -
3B3D
1
YTBE_BACSU
A:
[45-302]
-----
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
Q
V
E
E
G--
S
E
L
V
-
N
-
A
V
K
T
A
I
V
H
G
Y
R
S
I
D
T
A
A
I
Y
G
N
E
A
G
V
G
----
E
G
I
R
E
G
I
E
E
A
-----
G
I
-
S
R
E
D
L
F
I
T
S
K
V
W
N
A
D
L
G
Y
E
E
T
L
A
A
F
E
T
S
L
S
K
L
G
L
D
Y
L
D
L
Y
L
I
H
--
W
P
V
---
E
---------------------
G
K
---
Y
-
K
E
-----------------
A
W
R
A
L
E
T
L
Y
K
E
G
R
I
K
A
I
G
V
S
N
F
---
Q
I
H
H
L
E
D
L
M
T
A
A
--
E
I
K
P
M
I
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
I
R
Y
C
Q
N
----
Q
G
I
Q
M
E
A
W
S
P
L
M
Q
G
----------------
Q
---------
L
L
D
H
P
V
L
A
D
I
A
Q
T
Y
N
K
S
V
A
Q
I
I
L
R
W
D
L
Q
H
G
I
I
T
I
P
K
S
T
K
E
H
R
I
K
E
N
A
S
V
F
D
F
E
L
T
Q
D
D
M
N
R
I
D
A
L
N
--
E
N
---------------------------
5
PsiBlast_PDB
84.46
44%
-94
- C6 -
3O0K
4
?
A:
[37-283]
------------
I
P
Q
L
G
Y
G
V
W
Q
I
S
N
---
D
E
A
V
-
S
-
A
V
S
E
A
L
K
A
G
Y
R
H
I
D
T
A
T
I
Y
G
N
E
E
G
V
G
----
K
A
I
----
N
G
S
-----
G
I
-
A
R
A
D
I
F
L
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
K
A
F
D
T
S
L
K
K
L
G
T
D
Y
V
D
L
Y
L
I
H
WP
M
P
S
---
K
---------------------
D
L
---
F
-
M
E
-----------------
T
W
R
A
F
I
K
L
K
E
E
G
R
V
K
S
I
G
V
S
N
F
---
R
T
A
D
L
E
R
L
I
K
E
S
--
G
V
T
P
V
L
N
Q
I
E
L
H
P
Q
F
Q
Q
D
E
L
R
L
F
H
G
K
----
H
D
I
A
T
E
A
W
S
P
L
G
Q
G
--------------------------
L
L
E
D
P
T
L
K
S
I
A
E
K
H
A
K
S
V
A
Q
I
I
L
R
W
H
I
E
T
G
N
I
V
I
P
K
S
I
T
P
A
R
I
K
E
N
F
D
I
F
D
F
T
L
N
G
T
D
H
D
A
I
T
K
L
D
-------------------------------
26
PsiBlast_CBE
84.37
44%
-96
- C6 -
3O0K
4
?
B:
[37-283]
------------
I
P
Q
L
G
Y
G
V
W
Q
I
S
N
---
D
E
A
V
-
S
-
A
V
S
E
A
L
K
A
G
Y
R
H
I
D
T
A
T
I
Y
G
N
E
E
G
V
G
----
K
A
I
----
N
G
S
-----
G
I
-
A
R
A
D
I
F
L
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
K
A
F
D
T
S
L
K
K
L
G
T
D
Y
V
D
L
Y
L
I
H
WP
M
P
S
---
K
---------------------
D
L
---
F
-
M
E
-----------------
T
W
R
A
F
I
K
L
K
E
E
G
R
V
K
S
I
G
V
S
N
F
---
R
T
A
D
L
E
R
L
I
K
E
S
--
G
V
T
P
V
L
N
Q
I
E
L
H
P
Q
F
Q
Q
D
E
L
R
L
F
H
G
K
----
H
D
I
A
T
E
A
W
S
P
L
G
----------------------------
L
L
E
D
P
T
L
K
S
I
A
E
K
H
A
K
S
V
A
Q
I
I
L
R
W
H
I
E
T
G
N
I
V
I
P
K
S
I
T
P
A
R
I
K
E
N
F
D
I
F
D
F
T
L
N
G
T
D
H
D
A
I
T
K
L
D
-------------------------------
102
HHSearch
84.36
38%
-85
- C6 -
2WZM
1
Y2407_MYCS2
A:
[11-273]
I
P
T
V
T
L
N
-
D
D
N
T
L
P
V
V
G
I
G
V
G
E
L
S
D
---
S
E
A
E
-
R
-
S
V
S
A
A
L
E
A
G
Y
R
L
I
D
T
A
A
A
Y
G
N
E
A
A
V
G
----
R
A
I
----
A
A
S
-----
G
I
-
P
R
D
E
I
Y
V
T
T
K
L
A
T
P
D
Q
G
F
T
S
S
Q
A
A
A
R
A
S
L
E
R
L
G
L
D
Y
V
D
L
Y
L
I
H
--
W
P
G
---
G
D
T
S
------------------
K
Y
---
V
-
D
------------------
S
W
G
G
L
M
K
V
K
E
D
G
I
A
R
S
I
G
V
C
N
F
---
G
A
E
D
L
E
T
I
V
S
L
T
--
Y
F
T
P
A
V
N
Q
I
E
L
H
P
L
L
N
Q
A
A
L
R
E
V
N
A
G
----
Y
N
I
V
T
E
A
Y
G
P
L
G
V
G
-----
R
--------------------
L
L
D
H
P
A
V
T
A
I
A
E
A
H
G
R
T
A
A
Q
V
L
L
R
W
S
I
Q
L
G
N
V
V
I
S
R
S
A
N
P
E
R
I
A
S
N
L
D
V
F
G
F
E
L
T
A
D
E
M
E
T
L
N
G
L
D
--
D
G
----
T
R
-
F
-------------------
11
PsiBlast_PDB
84.34
48%
-96
- C6 -
3D3F
1
GR_BACSU
A:
[8-260]
---
V
K
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
K
V
E
N
---
G
N
E
A
T
E
-
S
V
K
A
A
I
K
N
G
Y
R
S
I
D
T
A
A
I
Y
K
N
E
E
G
V
G
----
I
G
I
----
K
E
S
-----
G
V
-
A
R
E
E
L
F
I
T
S
K
V
W
N
E
D
Q
G
Y
E
T
T
L
A
A
F
E
K
S
L
E
R
L
Q
L
D
Y
L
D
L
Y
L
I
H
--
W
P
G
---
K
---------------------
D
K
---
Y
K
D
------------------
T
W
R
A
L
E
K
L
Y
K
D
G
K
I
R
A
I
G
V
S
N
F
---
Q
V
H
H
L
E
E
L
L
K
D
A
--
E
I
K
P
M
V
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
R
D
Y
C
K
G
----
Q
G
I
Q
L
E
A
W
S
P
L
M
Q
G
----------------
Q
---------
L
L
D
N
E
V
L
T
Q
I
A
E
K
H
N
K
S
V
A
Q
V
I
L
R
W
D
L
Q
H
G
V
V
T
I
P
K
S
I
K
E
H
R
I
I
E
N
A
D
I
F
D
F
E
L
S
Q
E
D
M
D
K
I
D
A
L
--------------------------------
120
HHSearch
83.87
36%
-84
- C6 -
1MZR
4
DKGA_ECOLI
A:
[25-288]
P
T
V
I
K
L
Q
-
D
G
N
V
M
P
Q
L
G
L
G
V
W
Q
A
S
N
---
E
E
V
I
-
T
-
A
I
Q
K
A
L
E
V
G
Y
R
S
I
D
T
A
A
A
Y
K
N
E
E
G
V
G
----
K
A
L
----
K
N
A
-----
S
V
-
N
R
E
E
L
F
I
T
T
K
L
W
N
--
D
D
H
K
R
P
R
E
A
L
L
D
S
L
K
K
L
Q
L
D
Y
I
D
L
Y
L
M
H
--
W
P
V
---
P
AID------------------
H
Y
---
V
-
E
------------------
A
W
K
G
M
I
E
L
Q
K
E
G
L
I
K
S
I
G
V
C
N
F
---
Q
I
H
H
L
Q
R
L
I
D
E
T
--
G
V
T
P
V
I
N
Q
I
E
L
H
P
L
M
Q
Q
R
Q
L
H
A
W
N
A
T
----
H
K
I
Q
T
E
S
W
S
P
L
A
Q
G
-----
G
-
K
--------
G
---------
V
F
D
Q
K
V
I
R
D
L
A
D
K
Y
G
K
T
P
A
Q
I
V
I
R
W
H
L
D
S
G
L
V
V
I
P
K
S
V
T
P
S
R
I
A
E
N
F
D
V
W
D
F
R
L
D
K
D
E
L
G
E
I
A
K
L
D
--
Q
G
----
K
R
-
L
G
------------------
111
HHSearch
83.75
34%
-87
- C6 -
1S1P
3
AK1C3_HUMAN
A:
[6-308]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
P
E
VP
R
S
K
A
L
-
E
-
V
T
K
L
A
I
E
A
G
F
R
H
I
D
S
A
H
L
Y
N
N
E
E
Q
V
G
----
L
A
I
----
R
S
K
I
A
D
G-
S
V
-
K
R
E
D
I
F
Y
T
S
K
L
W
S
T
F
H
R
P
E
L
V
R
P
A
L
E
N
S
L
K
K
A
Q
L
D
Y
V
D
L
Y
L
I
H
--
S
P
M
---
S
LKPGEEL
S
P
T
D
ENGKVI
F
D
I
V
D
L
---
C
-
T
------------------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
---
N
R
R
Q
L
E
M
I
L
N
K
P
GL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
R
S
K
L
L
D
F
C
K
S
----
K
D
I
V
L
V
A
Y
S
A
L
G
S
Q
-----
R
-
D
--------
K
RWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
A
E
D
M
K
A
I
D
G
L
D
--
R
N
----
L
H
-
Y
F
N
S
----------------
104
HHSearch
83.48
40%
-86
- C6 -
1VBJ
2
PGFS_TRYBB
A:
[12-280]
---
L
K
L
S
-
N
G
V
M
M
P
V
L
G
F
G
M
W
K
L
Q
D
G--
N
E
A
E
-
T
-
A
T
M
W
A
I
K
S
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
A
G
----
R
A
I
----
A
S
C
-----
G
V
-
P
R
E
E
L
F
V
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
S
A
F
E
K
S
I
K
K
L
G
L
E
Y
V
D
L
Y
L
I
H
--
W
P
G
---
K
D--------------------
K
F
---
I
-
D
------------------
T
W
K
A
F
E
K
L
Y
A
D
K
K
V
R
A
I
G
V
S
N
F
---
H
E
H
H
I
E
E
L
L
K
H
C
--
K
V
A
P
M
V
N
Q
I
E
L
H
P
L
L
N
Q
K
A
L
C
E
Y
C
K
S
----
K
N
I
A
V
T
A
W
S
P
L
G
Q
G
-----
H
--------------------
L
V
E
D
A
R
L
K
A
I
G
G
K
Y
G
K
T
A
A
Q
V
M
L
R
W
E
I
Q
A
G
V
I
T
I
P
K
S
G
N
E
A
R
I
K
E
N
G
N
I
F
D
F
E
L
T
A
E
D
I
Q
V
I
D
G
M
N
--
A
G
----
H
R
-
Y
G
----
P
D
P
E
V
F
M
N
D
-----
25
PsiBlast_CBE
82.81
44%
-95
- C6 -
3O0K
3
?
C:
[37-283]
------------
I
P
Q
L
G
Y
G
V
W
Q
I
S
N
---
D
E
A
V
-
S
-
A
V
S
E
A
L
K
A
G
Y
R
H
I
D
T
A
T
I
Y
G
N
E
E
G
V
G
----
K
A
I
----
N
G
S
-----
G
I
-
A
R
A
D
I
F
L
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
K
A
F
D
T
S
L
K
K
L
G
T
D
Y
V
D
L
Y
L
I
H
WP
M
P
S
---
K
---------------------
D
L
---
F
-
M
E
-----------------
T
W
R
A
F
I
K
L
K
E
E
G
R
V
K
S
I
G
V
S
N
F
---
R
T
A
D
L
E
R
L
I
K
E
S
--
G
V
T
P
V
L
N
Q
I
E
L
H
P
Q
F
Q
Q
D
E
L
R
L
F
H
G
K
----
H
D
I
A
T
E
A
W
S
P
L
G
----------------------------
L
L
E
D
P
T
L
K
S
I
A
E
K
H
A
K
S
V
A
Q
I
I
L
R
W
H
I
E
T
G
N
I
V
I
P
K
S
I
T
P
A
R
I
K
E
N
F
D
I
F
D
F
T
L
N
G
T
D
H
D
A
I
T
K
L
D
-------------------------------
50
PsiBlast_CBE
82.71
33%
-89
- C6 -
4GAC
2
AK1A1_MOUSE
B:
[12-301]
-----------
K
M
P
L
I
G
L
G
T
W
K
S
E
P
---
G
Q
V
K
-
A
-
A
I
K
H
A
L
S
A
G
Y
R
H
I
D
C
A
S
V
Y
G
N
E
T
E
I
G
----
E
A
L
----
K
E
S
VGSGK
A
V
-
P
R
E
E
L
F
V
T
S
K
L
W
N
T
K
H
H
P
E
D
V
E
P
A
L
R
K
T
L
A
D
L
Q
L
E
Y
L
D
L
Y
L
M
H
--
W
P
Y
---
A
---------------------
F
E
---
R
-
G
DNPFPKGTVRYDSTH
Y
K
E
T
W
K
A
L
E
V
L
V
A
K
G
L
V
K
A
L
G
L
S
N
F
---
N
S
R
Q
I
D
D
V
L
S
V
A
--
S
V
R
P
A
V
L
Q
V
E
C
H
P
Y
L
A
Q
N
E
L
I
A
H
C
H
A
----
R
G
L
E
V
T
A
Y
S
P
L
G
-------------------PDEPV----
L
L
E
E
P
V
V
L
A
L
A
E
K
H
G
R
S
P
A
Q
I
L
L
R
W
Q
V
Q
R
K
V
I
C
I
P
K
S
I
N
P
S
R
I
L
Q
N
I
Q
V
F
D
F
T
F
S
P
E
E
M
K
Q
L
D
A
L
N
--
K
N
---------------------------
24
PsiBlast_CBE
82.46
44%
-93
- C6 -
3O0K
3
?
D:
[37-283]
------------
I
P
Q
L
G
Y
G
V
W
Q
I
S
N
---
D
E
A
V
-
S
-
A
V
S
E
A
L
K
A
G
Y
R
H
I
D
T
A
T
I
Y
G
N
E
E
G
V
G
----
K
A
I
----
N
G
S
-----
G
I
-
A
R
A
D
I
F
L
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
K
A
F
D
T
S
L
K
K
L
G
T
D
Y
V
D
L
Y
L
I
H
WP
M
P
S
---
K
---------------------
D
L
---
F
-
M
E-----------------
T
W
R
A
F
I
K
L
K
E
E
G
R
V
K
S
I
G
V
S
N
F
---
R
T
A
D
L
E
R
L
I
K
E
S
--
G
V
T
P
V
L
N
Q
I
E
L
H
P
Q
F
Q
Q
D
E
L
R
L
F
H
G
K
----
H
D
I
A
T
E
A
W
S
P
L
G
-------
K
--------------------
L
L
E
D
P
T
L
K
S
I
A
E
K
H
A
K
S
V
A
Q
I
I
L
R
W
H
I
E
T
G
N
I
V
I
P
K
S
I
T
P
A
R
I
K
E
N
F
D
I
F
D
F
T
L
N
G
T
D
H
D
A
I
T
K
L
D
-------------------------------
8
PsiBlast_PDB
82.43
41%
-87
- C6 -
1VBJ
2
PGFS_TRYBB
A:
[12-277]
---
L
K
L
S
-
N
G
V
M
M
P
V
L
G
F
G
M
W
K
L
Q
D
---
G
N
E
A
-
E
T
A
T
M
W
A
I
K
S
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
A
G
----
R
A
I
----
A
S
C
-----
G
V
-
P
R
E
E
L
F
V
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
S
A
F
E
K
S
I
K
K
L
G
L
E
Y
V
D
L
Y
L
I
H
--
W
P
G
---
K
---------------------
D
K
---
F
I
D
------------------
T
W
K
A
F
E
K
L
Y
A
D
K
K
V
R
A
I
G
V
S
N
F
---
H
E
H
H
I
E
E
L
L
K
H
C
--
K
V
A
P
M
V
N
Q
I
E
L
H
P
L
L
N
Q
K
A
L
C
E
Y
C
K
S
----
K
N
I
A
V
T
A
W
S
P
L
G
Q
G
----------------
H
---------
L
V
E
D
A
R
L
K
A
I
G
G
K
Y
G
K
T
A
A
Q
V
M
L
R
W
E
I
Q
A
G
V
I
T
I
P
K
S
G
N
E
A
R
I
K
E
N
G
N
I
F
D
F
E
L
T
A
E
D
I
Q
V
I
D
G
M
--------
N
A
G
-
H
R
Y
G
P
D
P
E
V
F
----------
114
HHSearch
81.98
39%
-92
- C6 -
3WBW
2
?
A:
[16-269]
--
V
I
S
F
H
-
D
G
H
T
M
P
Q
I
G
L
G
V
W
E
T
P
P
---
D
E
T
A
-
E
-
V
V
K
E
A
V
K
L
G
Y
R
S
V
D
T
A
R
L
Y
K
N
E
E
G
V
G
----
K
G
L
----
E
D
----------
H
P
E
I
F
L
T
T
K
L
W
N
D
E
Q
G
Y
D
S
T
L
R
A
Y
E
E
S
A
R
L
L
R
R
P
V
L
D
L
Y
L
I
H
--
W
P
M
---
P
AQG------------------
Q
Y
---
V
-
E
------------------
T
W
K
A
L
V
E
L
K
K
S
G
R
V
K
S
I
G
V
S
N
F
---
E
S
E
H
L
E
R
I
M
D
A
T
--
G
V
V
P
V
V
N
Q
I
E
L
H
P
D
F
Q
Q
R
A
L
R
E
F
H
E
K
----
H
N
I
R
T
E
S
W
R
P
L
G
K
G
-----
R
--------------------
V
L
S
D
E
R
I
G
K
I
A
E
K
H
S
R
T
P
A
Q
V
V
I
R
W
H
L
Q
N
G
L
I
V
I
P
K
S
V
N
P
K
R
L
A
E
N
L
D
V
F
G
F
V
L
D
A
D
D
M
Q
A
I
E
Q
M
D
--
R
K
---------------------------
39
PsiBlast_CBE
81.83
39%
-85
- C6 -
3WBW
2
?
B:
[25-281]
------------
M
P
Q
I
G
L
G
V
W
E
T
P
P
---
D
E
T
A
-
E
-
V
V
K
E
A
V
K
L
G
Y
R
S
V
D
T
A
R
L
Y
K
N
E
E
G
V
G
----
K
G
L
----
E
----------
D
H
P
E
I
F
L
T
T
K
L
W
N
D
E
Q
G
Y
D
S
T
L
R
A
Y
E
E
S
A
R
L
L
R
R
P
V
L
D
L
Y
L
I
H
--
W
P
M
PAQ
G
---------------------
Q
Y
---
V
-
E
------------------
T
W
K
A
L
V
E
L
K
K
S
G
R
V
K
S
I
G
V
S
N
F
ESE
H
L
E
R
I
M
D
A
---
T
--
G
V
V
P
V
V
N
Q
I
E
L
H
P
D
F
Q
Q
R
A
L
R
E
F
H
E
K
----
H
N
I
R
T
E
S
W
R
P
L
--
G
-----
K
-
G
--------
R
---------
V
L
S
D
E
R
I
G
K
I
A
E
K
H
S
R
T
P
A
Q
V
V
I
R
W
H
L
Q
N
G
L
I
V
I
P
K
S
V
N
P
K
R
L
A
E
N
L
D
V
F
G
F
V
L
D
A
D
D
M
Q
A
I
E
Q
M
D
--
R
K
---
D
G
R
-
M
--
G
A
D
P
N
T
A
K
---------
40
PsiBlast_CBE
81.81
39%
-87
- C6 -
3WBY
1
?
B:
[25-281]
------------
M
P
Q
I
G
L
G
V
W
E
T
P
P
---
D
E
T
A
-
E
-
V
V
K
E
A
V
K
L
G
Y
R
S
V
A
T
A
R
L
Y
K
N
E
E
G
V
G
----
K
G
L
----
E
----------
D
H
P
E
I
F
L
T
T
K
L
W
N
D
E
Q
G
Y
D
S
T
L
R
A
Y
E
E
S
A
R
L
L
R
R
P
V
L
D
L
Y
L
I
H
--
W
P
M
PAQ
G
---------------------
Q
Y
---
V
-
E
------------------
T
W
K
A
L
V
E
L
K
K
S
G
R
V
K
S
I
G
V
S
N
F
ESE
H
L
E
R
I
M
D
A
---
T
--
G
V
V
P
V
V
N
Q
I
E
L
H
P
D
F
Q
Q
R
A
L
R
E
F
H
E
K
----
H
N
I
R
T
E
S
W
R
P
L
--
G
-----
K
-
G
--------
R
---------
V
L
S
D
E
R
I
G
K
I
A
E
K
H
S
R
T
P
A
Q
V
V
I
R
W
H
L
Q
N
G
L
I
V
I
P
K
S
V
N
P
K
R
L
A
E
N
L
D
V
F
G
F
V
L
D
A
D
D
M
Q
A
I
E
Q
M
D
--
R
K
---
D
G
R
-
M
--
G
A
D
P
N
T
A
K
---------
110
HHSearch
81.66
39%
-83
- C6 -
1US0
4
ALDR_HUMAN
A:
[1-299]
M
A
S
R
I
L
L
N
N
G
A
K
M
P
I
L
G
L
G
T
W
K
S
P
P
---
G
Q
V
T
-
E
-
A
V
K
V
A
I
D
V
G
Y
R
H
I
D
C
A
H
V
Y
Q
N
E
N
E
V
G
----
V
A
I
----
Q
E
K
L
R
E
Q-
V
V
-
K
R
E
E
L
F
I
V
S
K
L
W
C
T
Y
H
E
K
G
L
V
K
G
A
C
Q
K
T
L
S
D
L
K
L
D
Y
L
D
L
Y
L
I
H
--
W
P
T
---
G
FKPGKEF
F
P
L
D
ESGNVVPSDT
N
I
---
L
-
D
------------------
T
W
A
A
M
E
E
L
V
D
E
G
L
V
K
A
I
G
I
S
N
F
---
N
H
L
Q
V
E
M
I
L
N
K
P
GL
K
Y
K
P
A
V
N
Q
I
E
C
H
P
Y
L
T
Q
E
K
L
I
Q
Y
C
Q
S
----
K
G
I
V
V
T
A
Y
S
P
L
G
S
P
-----
D
-
R
PWAKPEDP
S
---------
L
L
E
D
P
R
I
K
A
I
A
A
K
H
N
K
T
T
A
Q
V
L
I
R
F
P
M
Q
R
N
L
V
V
I
P
K
S
V
T
P
E
R
I
A
E
N
F
K
V
F
D
F
E
L
S
S
Q
D
M
T
T
L
L
S
Y
N
--
R
N
----
W
R
-
V
C
------------------
15
PsiBlast_PDB
81.35
39%
-85
- C6 -
3WBY
1
?
A:
[25-281]
------------
M
P
Q
I
G
L
G
V
W
E
T
P
P
---
D
E
T
A
-
E
-
V
V
K
E
A
V
K
L
G
Y
R
S
V
A
T
A
R
L
Y
K
N
E
E
G
V
G
----
K
G
L
----
E
----------
D
H
P
E
I
F
L
T
T
K
L
W
N
D
E
Q
G
Y
D
S
T
L
R
A
Y
E
E
S
A
R
L
L
R
R
P
V
L
D
L
Y
L
I
H
--
W
P
M
PAQ
G
---------------------
Q
Y
---
V
-
E
------------------
T
W
K
A
L
V
E
L
K
K
S
G
R
V
K
S
I
G
V
S
N
F
E
S
E
H
L
E
R
I
M
D
A
---
T
--
G
V
V
P
V
V
N
Q
I
E
L
H
P
D
F
Q
Q
R
A
L
R
E
F
H
E
K
----
H
N
I
R
T
E
S
W
R
P
L
--
G
-----
K
-
G
--------
R
---------
V
L
S
D
E
R
I
G
K
I
A
E
K
H
S
R
T
P
A
Q
V
V
I
R
W
H
L
Q
N
G
L
I
V
I
P
K
S
V
N
P
K
R
L
A
E
N
L
D
V
F
G
F
V
L
D
A
D
D
M
Q
A
I
E
Q
M
D
--
R
K
---
D
G
R
-
M
--
G
A
D
P
N
T
A
K
---------
121
HHSearch
81.26
35%
-81
- C6 -
3H7U
2
AKRC9_ARATH
A:
[25-308]
I
T
F
F
K
L
N
-
T
G
A
K
F
P
S
V
G
L
G
T
W
Q
A
S
P
---
G
L
V
G
-
D
-
A
V
A
A
A
V
K
I
G
Y
R
H
I
D
C
A
Q
I
Y
G
N
E
K
E
I
G
----
A
V
L
----
K
K
L
F
E
D
R-
V
V
-
K
R
E
D
L
F
I
T
S
K
L
W
C
T
D
H
D
P
Q
D
V
P
E
A
L
N
R
T
L
K
D
L
Q
L
E
Y
V
D
L
Y
L
I
H
--
W
P
A
---
R
I
K
K
GSVGIKPENLLPV-----
D
I
---
P
-
S
------------------
T
W
K
A
M
E
A
L
Y
D
S
G
K
A
R
A
I
G
V
S
N
F
---
S
T
K
K
L
A
D
L
L
E
L
A
--
R
V
P
P
A
V
N
Q
V
E
C
H
P
S
W
R
Q
T
K
L
Q
E
F
C
K
S
----
K
G
V
H
L
S
A
Y
S
P
L
G
S
P
-----
G
-
T
TWLKS---
D
---------
V
L
K
N
P
I
L
N
M
V
A
E
K
L
G
K
S
P
A
Q
V
A
L
R
W
G
L
Q
M
G
H
S
V
L
P
K
S
T
N
E
G
R
I
K
E
N
F
N
V
F
D
W
S
I
P
D
Y
M
F
A
K
F
A
E
I
E
--
Q
A
---------------------------
28
PsiBlast_CBE
81.14
41%
-84
- C6 -
1VBJ
2
PGFS_TRYBB
B:
[12-277]
---
L
K
L
S
-
N
G
V
M
M
P
V
L
G
F
G
M
W
K
L
Q
D
---
G
N
E
A
-
E
T
A
T
M
W
A
I
K
S
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
A
G
----
R
A
I
----
A
S
C
-----
G
V
-
P
R
E
E
L
F
V
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
S
A
F
E
K
S
I
K
K
L
G
L
E
Y
V
D
L
Y
L
I
H
--
W
P
G
---
K
---------------------
D
K
---
F
I
D
------------------
T
W
K
A
F
E
K
L
Y
A
D
K
K
V
R
A
I
G
V
S
N
F
---
H
E
H
H
I
E
E
L
L
K
H
C
--
K
V
A
P
M
V
N
Q
I
E
L
H
P
L
L
N
Q
K
A
L
C
E
Y
C
K
S
----
K
N
I
A
V
T
A
W
S
P
L
G
Q
G
----------------
H
---------
L
V
E
D
A
R
L
K
A
I
G
G
K
Y
G
K
T
A
A
Q
V
M
L
R
W
E
I
Q
A
G
V
I
T
I
P
K
S
G
N
E
A
R
I
K
E
N
G
N
I
F
D
F
E
L
T
A
E
D
I
Q
V
I
D
G
M
--------
N
A
G
-
H
R
Y
G
P
D
P
E
V
F
----------
17
PsiBlast_PDB
80.62
38%
-80
- C6 -
2WZM
1
Y2407_MYCS2
A:
[14-271]
---
V
T
L
N
-
D
D
N
T
L
P
V
V
G
I
G
V
G
E
L
S
D
---
S
E
A
E
-
R
-
S
V
S
A
A
L
E
A
G
Y
R
L
I
D
T
A
A
A
Y
G
N
E
A
A
V
G
----
R
A
I
----
A
A
S
-----
G
I
-
P
R
D
E
I
Y
V
T
T
K
L
A
T
P
D
Q
G
F
T
S
S
Q
A
A
A
R
A
S
L
E
R
L
G
L
D
Y
V
D
L
Y
L
I
H
--
W
P
G
---
G
---------------------
D
T
S
K
Y
V
-
D
------------------
S
W
G
G
L
M
K
V
K
E
D
G
I
A
R
S
I
G
V
C
N
F
---
G
A
E
D
L
E
T
I
V
S
L
T
--
Y
F
T
P
A
V
N
Q
I
E
L
H
P
L
L
N
Q
----
A
A
L
R
E
V
N
A
G
Y
N
I
V
T
E
A
Y
G
P
L
G
V
G
-----
R
--------------------
L
L
D
H
P
A
V
T
A
I
A
E
A
H
G
R
T
A
A
Q
V
L
L
R
W
S
I
Q
L
G
N
V
V
I
S
R
S
A
N
P
E
R
I
A
S
N
L
D
V
F
G
F
E
L
T
A
D
E
M
E
T
L
N
G
L
D
--
D
G
---
T
-----------------------
13
PsiBlast_PDB
80.37
39%
-85
- C6 -
3WBW
2
?
A:
[25-281]
------------
M
P
Q
I
G
L
G
V
W
E
T
P
P
---
D
E
T
A
-
E
-
V
V
K
E
A
V
K
L
G
Y
R
S
V
D
T
A
R
L
Y
K
N
E
E
G
V
G
----
K
G
L
----
E
----------
D
H
P
E
I
F
L
T
T
K
L
W
N
D
E
Q
G
Y
D
S
T
L
R
A
Y
E
E
S
A
R
L
L
R
R
P
V
L
D
L
Y
L
I
H
--
W
P
M
PAQ
G
---------------------
Q
Y
---
V
-
E
------------------
T
W
K
A
L
V
E
L
K
K
S
G
R
V
K
S
I
G
V
S
N
F
E
S
E
H
L
E
R
I
M
D
A
---
T
--
G
V
V
P
V
V
N
Q
I
E
L
H
P
D
F
Q
Q
R
A
L
R
E
F
H
E
K
----
H
N
I
R
T
E
S
W
R
P
L
--
G
-----
K
-
G
--------
R
---------
V
L
S
D
E
R
I
G
K
I
A
E
K
H
S
R
T
P
A
Q
V
V
I
R
W
H
L
Q
N
G
L
I
V
I
P
K
S
V
N
P
K
R
L
A
E
N
L
D
V
F
G
F
V
L
D
A
D
D
M
Q
A
I
E
Q
M
D
--
R
K
---
D
G
R
-
M
--
G
A
D
P
N
T
A
K
---------
43
PsiBlast_CBE
79.96
39%
-76
- C6 -
1A80
1
DKGA_CORSC
A:
[12-276]
-----------
S
I
P
Q
L
G
Y
G
V
F
K
V
P
P
---
A
D
T
Q
-
R
-
A
V
E
E
A
L
E
V
G
Y
R
H
I
D
T
A
A
I
Y
G
N
E
E
G
V
G
----
A
A
I
----
A
A
S
-----
G
I
-
A
R
D
D
L
F
I
T
T
K
L
W
N
D
R
H
D
G
D
E
P
A
A
A
I
A
E
S
L
A
K
L
A
L
D
Q
V
D
L
Y
L
V
H
--
W
P
T
PAA
D
---------------------
N
Y
---
V
-
H
------------------
A
W
E
K
M
I
E
L
R
A
A
G
L
T
R
S
I
G
V
S
N
H
---
L
V
P
H
L
E
R
I
V
A
A
T
--
G
V
V
P
A
V
N
Q
I
E
L
H
P
A
Y
Q
Q
R
E
I
T
D
W
A
A
A
----
H
D
V
K
I
E
S
W
G
P
L
G
Q
G
-----
K
-
Y
--------
D
---------
L
F
G
A
E
P
V
T
A
A
A
A
A
H
G
K
T
P
A
Q
A
V
L
R
W
H
L
Q
K
G
F
V
V
F
P
K
S
V
R
R
E
R
L
E
E
N
L
D
V
F
D
F
D
L
T
D
T
E
I
A
A
I
D
A
M
D
--
P
G
---
D
G
S
-
G
R
V
S
A
H
P
D
E
V
----------
16
PsiBlast_PDB
79.91
37%
-83
- C6 -
1MZR
4
DKGA_ECOLI
A:
[36-284]
------------
M
P
Q
L
G
L
G
V
W
Q
A
S
N
---
E
E
V
I
-
T
-
A
I
Q
K
A
L
E
V
G
Y
R
S
I
D
T
A
A
A
Y
K
N
E
E
G
V
G
----
K
A
L
----
K
N
A
-----
S
V
-
N
R
E
E
L
F
I
T
T
K
L
W
--
N
D
D
H
K
R
P
R
E
A
L
L
D
S
L
K
K
L
Q
L
D
Y
I
D
L
Y
L
M
H
--
W
P
V
---
P
---------------------
A
I
DH
Y
V
-
E
------------------
A
W
K
G
M
I
E
L
Q
K
E
G
L
I
K
S
I
G
V
C
N
F
---
Q
I
H
H
L
Q
R
L
I
D
E
T
--
G
V
T
P
V
I
N
Q
I
E
L
H
P
L
M
Q
Q
R
Q
L
H
A
W
N
A
T
----
H
K
I
Q
T
E
S
W
S
P
L
A
Q
G
-----
G
-
K
--------
G
---------
V
F
D
Q
K
V
I
R
D
L
A
D
K
Y
G
K
T
P
A
Q
I
V
I
R
W
H
L
D
S
G
L
V
V
I
P
K
S
V
T
P
S
R
I
A
E
N
F
D
V
W
D
F
R
L
D
K
D
E
L
G
E
I
A
K
L
D
--
Q
G
---------------------------
42
PsiBlast_CBE
79.80
38%
-80
- C6 -
2WZM
1
Y2407_MYCS2
B:
[14-271]
---
V
T
L
N
-
D
D
N
T
L
P
V
V
G
I
G
V
G
E
L
S
D
---
S
E
A
E
-
R
-
S
V
S
A
A
L
E
A
G
Y
R
L
I
D
T
A
A
A
Y
G
N
E
A
A
V
G
----
R
A
I
----
A
A
S
-----
G
I
-
P
R
D
E
I
Y
V
T
T
K
L
A
T
P
D
Q
G
F
T
S
S
Q
A
A
A
R
A
S
L
E
R
L
G
L
D
Y
V
D
L
Y
L
I
H
--
W
P
G
---
G
---------------------
D
T
SKY
V
-
D
------------------
S
W
G
G
L
M
K
V
K
E
D
G
I
A
R
S
I
G
V
C
N
F
---
G
A
E
D
L
E
T
I
V
S
L
T
--
Y
F
T
P
A
V
N
Q
I
E
L
H
P
L
L
N
Q
----
A
A
L
R
E
VNAG
Y
N
I
V
T
E
A
Y
G
P
L
G
V
G
-----
R
--------------------
L
L
D
H
P
A
V
T
A
I
A
E
A
H
G
R
T
A
A
Q
V
L
L
R
W
S
I
Q
L
G
N
V
V
I
S
R
S
A
N
P
E
R
I
A
S
N
L
D
V
F
G
F
E
L
T
A
D
E
M
E
T
L
N
G
L
D
--
D
G
---
T
-----------------------
98
PsiBlast_CBE
79.41
31%
-82
- C6 -
3H7U
2
AKRC9_ARATH
A:
[25-318]
I
T
F
F
K
L
N
-
T
G
A
K
F
P
S
V
G
L
G
T
W
Q
A
S
P
---
G
L
V
G
-
D
-
A
V
A
A
A
V
K
I
G
Y
R
H
I
D
C
A
Q
I
Y
G
N
E
K
E
I
G
A
V
L
K
K
L
F
----
E
D
R
-----
V
V
-
K
R
E
D
L
F
I
T
S
K
L
W
C
T
D
H
D
P
Q
D
V
P
E
A
L
N
R
T
L
K
D
L
Q
L
E
Y
V
D
L
Y
L
I
H
--
W
P
A
---
R
I
K
K
GSVGIKPENLLPV-----
D
I
---
P
-
S
------------------
T
W
K
A
M
E
A
L
Y
D
S
G
K
A
R
A
I
G
V
S
N
F
---
S
T
K
K
L
A
D
L
L
E
L
A
--
R
V
P
P
A
V
N
Q
V
E
C
H
P
S
W
R
Q
T
K
L
Q
E
F
C
K
S
----
K
G
V
H
L
S
A
Y
S
P
L
G
S
P
GTTWL
K
-
S
--------
D
---------
V
L
K
N
P
I
L
N
M
V
A
E
K
L
G
K
S
P
A
Q
V
A
L
R
W
G
L
Q
M
G
H
S
V
L
P
K
S
T
N
E
G
R
I
K
E
N
F
N
V
F
D
W
S
I
P
D
Y
M
F
A
K
F
A
E
I
E
--
Q
A
R
LV
T
G
S
-
F
L
V
H
----------------
53
PsiBlast_CBE
78.56
38%
-77
- C6 -
1M9H
2
DKGA_CORSC
A:
[13-275]
-----------
S
I
P
Q
L
G
Y
G
V
Y
K
V
P
P
---
A
D
T
Q
-
R
-
A
V
E
E
A
L
E
V
G
Y
R
H
I
D
T
A
A
I
Y
G
N
E
E
G
V
G
----
A
A
I
----
A
A
S
-----
G
I
-
A
R
D
D
L
F
I
T
T
K
L
W
N
D
R
H
D
G
D
E
P
A
A
A
I
A
E
S
L
A
K
L
A
L
D
Q
V
D
L
Y
L
V
H
--
W
P
T
PAA
D
---------------------
N
Y
---
V
-
H
------------------
A
W
E
K
M
I
E
L
R
A
A
G
L
T
R
S
I
G
V
S
N
H
---
L
V
P
H
L
E
R
I
V
A
A
T
--
G
V
V
P
A
V
N
Q
I
E
L
H
P
A
Y
Q
Q
R
E
I
T
D
W
A
A
A
----
H
D
V
K
I
E
S
W
G
P
L
G
Q
G
-----
K
-
Y
--------
D
---------
L
F
G
A
E
P
V
T
A
A
A
A
A
H
G
K
T
P
A
Q
A
V
L
R
W
H
L
Q
K
G
F
V
V
F
P
G
S
V
R
R
E
H
L
E
E
N
L
D
V
F
D
F
D
L
T
D
T
E
I
A
A
I
D
A
M
D
PG
D
G
---
S
G
R
-
V
S
G
H
P
D
--------------