@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA2013_2: (2016-03-31 )
MIVLYLEEVPKFISNLKERLNYSVHVSTGKMPIIALEKEKVLTITTECECKKLI
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------...--..------....10.......--.20----...--.--.-.-..-.-----30.-.......40........50...-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
V
--
L
Y
------
L
E
E
V
P
K
F
I
S
N
L
K
E
--RL-----
N
Y
S
--
V
--
H
-V-ST-G-----K
M
P
-
I
I
A
LEKE
K
V
L
T
I
TTE
C
E
CKKLI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
78.66
27%
-80
- C2 -
4TZ4
-
DDB1_HUMAN
A:
[1-1146]
S
Y
N
Y
V
V
T
AQKPTAVN
G
C
V
T
G
HFTSAE
D
L
N
L
L
I
A
KNT
R
L
E
I
Y
V
V
T
ALRPV
K
E
V
G
M
YGKIA
V
M
E
L
F
R
P
K
GES
K
D
L
L
F
I
L
T
AKY
N
A
C
I
L
E
Y
K
QS
I
D
I
I
T
R
A
H
G
N
VQDRIGRPSET
G
I
I
G
I
I
D
PECR
M
I
G
L
R
LYDG
L
F
K
V
I
P
LDRDNKEL
K
A
F
N
I
R
L
EELHVI
D
V
K
F
L
Y
GCQ
A
P
T
I
C
F
V
Y
Q
D
PQ
G
R
H
V
K
T
Y
E
V
S
LREKEFNKGPWKQNVEAEAS
M
V
I
A
V
P
EPF
G
G
A
I
I
I
G
QE
S
I
T
Y
H
N
GD
K
Y
L
A
I
A
P
PIIKQ
S
T
I
V
C
HNRVDPNGS
R
Y
L
L
G
D
ME
G
R
L
F
M
L
L
L
E
KTLK
D
L
R
V
E
L
LGETSIAE
C
L
T
Y
L
D
NG
V
V
F
V
G
S
RL
G
D
S
Q
L
V
K
L
NEQ
G
S
Y
V
V
A
M
E
T
F
T
N
LGPIV
D
M
C
V
V
DLEQ
G
Q
L
V
T
CSGAFKE
G
S
L
R
I
I
R
N
G
I
G
I
H
E
H
A
S
I
D
L
P
GIK
G
L
W
P
L
R
SDPETDD
T
L
V
L
S
F
VG
Q
T
R
V
L
M
L
N
GE
E
V
E
E
T
E
L
M
GFVDDQQTF
F
C
G
N
V
A
HQ
Q
L
I
Q
I
T
SA
S
V
R
L
V
S
Q
EPKALV
S
E
W
K
E
PQAKNIS
V
A
S
C
N
SS
Q
V
V
V
A
V
GR
A
L
Y
Y
L
Q
I
H
PQ
E
L
R
Q
I
S
H
T
E
M
EVA
C
L
D
I
T
P
LGLSP
L
C
A
I
G
LTDISA
R
I
L
K
L
PSFELHKEMLGGIIPR
S
I
L
M
T
T
F
ES
S
H
Y
L
L
C
A
L
GDG
A
L
F
Y
F
G
L
N
IETGLLSDK
K
V
T
L
G
TQ
P
T
V
L
R
T
F
R
SS
T
T
N
V
F
A
C
S
D
R
P
T
V
--
I
Y
------
S
N
H
K
L
V
F
S
N
V
N
L
K
--
E
V
-----
N
Y
M
--
C
--
P
-
L
-
N
S
-
D
-----
G
Y
P
D
S
L
A
L
A
N
N
S
T
L
T
I
G
T
I
D
E
I
Q
K
L
H
I
R
T
V
P
LY
E
S
P
R
K
I
C
Y
Q
EVSQ
C
F
G
V
L
S
S
R
I
E
V
Q
DTTALRPSASTQAL
S
S
S
V
SSE
E
V
E
V
H
N
L
L
I
I
D
QHTFEVL
H
A
H
Q
F
L
QN
E
Y
A
L
S
L
V
S
C
K
L
GKDP
N
T
Y
F
I
V
G
T
A
M
V
Y
PEEAEPK
Q
G
R
I
V
V
F
Q
Y
S
DGKLQTV
A
E
K
E
V
KGAVY
S
M
V
E
F
NG
K
L
L
A
S
I
NS
T
V
R
L
Y
E
W
T
TEK
E
L
R
T
E
C
N
H
Y
N
NIMAL
Y
L
K
T
K
GD
F
I
L
V
G
D
LMR
S
V
L
L
L
A
Y
K
PMEG
N
F
E
E
I
A
R
D
F
N
P
N
WMS
A
V
E
I
LDDD
N
F
L
G
A
E
N
AF
N
L
F
V
C
Q
KDEERQHLQEV
G
L
F
HLGEFVN
V
F
C
H
G
S
LVT
Q
G
S
V
L
F
G
T
VNG
M
I
G
L
V
T
S
L
S
E
S
W
Y
N
L
L
L
D
M
Q
N
R
L
N
K
V
IKSVGKIE
H
S
F
W
R
SFHTKTEPATGFID
G
D
L
I
E
S
F
LDIS
R
P
K
M
Q
E
V
V
A
N
L
Q
Y
D
D
GKREAT
A
D
D
L
I
K
V
V
E
E
L
T
R
I
H
W
S
H
P
Q
FE
22
Fugue
70.57
18%
-119
- C4 -
3VBC
-
I17RB_MOUSE
A:
[325-481]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLP
L
I
K
V
L
V
--
V
Y
P
SEICF
H
H
T
V
C
R
F
T
D
F
L
Q
N
--
Y
C
-----
R
S
E
--
V
--
I
-
L
-
E
A
-
W
-----
Q
A
A
-
A
I
A
E
M
G
P
V
Q
W
L
T
T
Q
K
Q
A
A
D
K
V
V
F
L
L
P
SQDL
F
P
L
A
F
N
L
F
CSDFSSQTHLHK
Y
L
V
V
Y
L
G
G
A
D
L
KGDYNALSV
C
P
Q
Y
H
L
MKD
A
T
A
F
H
T
E
L
L
K
A
T
Q-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
69.14
20%
-37
- C4 -
4RKS
4
MV3K_THEAC
A:
[21-337]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TYR
S
I
G
S
T
A
Y
P
T
I
G
VVLLGGIANPVTRTPL
H
T
S
A
G
I
A
Y
S
D
SCGSI
R
S
E
T
R
I
Y
A
D
E
A
T
H
I
Y
F
NGTESTDDNRS
V
R
R
V
L
D
R
Y
S
S
V
F
E
E
A
FGTK
T
V
S
Y
S
S
Q
N
F
GILSGSS
D
A
G
A
A
S
I
G
A
A
I
L
G
L
KPDLD
P
H
D
V
E
N
D
L
RAVSES
A
G
R
S
L
F
G
G
L
T
I
T
W
S
DGF
H
A
Y
T
E
K
ILDPEAFSG
Y
S
I
V
A
F
A
F
DYQRNP
S
D
V
I
H
Q
N
I
VRSDL
Y
P
A
R
K
K
H
A
D
E
H
A
H
M
I
K
E
Y
A
K
T
ND
I
K
G
I
F
D
L
A
Q
E
D
T
E
E
Y
H
S
I
L
R
G
V
G
V
N
--
V
I
------
R
E
N
M
Q
K
L
I
S
Y
L
K
L
I
R
K
D
-----
Y
W
N
--
A
--
Y
-
I
-
V
T
-
G
GS
N
V
-
Y
V
A
-
V
E
S
E
N
A
D
R
L
F
S
I
E
N
T
F
G
S
K
K
K
M
L
R
I
V
G
G
A
W
H
R
RPE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
61.62
25%
-32
* C4 *
3FN2
1
?
A:
[6-102]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YT
M
Q
R
D
N
Q
K
T
L
A
--
V
Y
M
-----
F
E
E
I
N
R
D
V
E
Y
L
S
G
--
R
L
-----
S
----------------------------
E
K
E
L
K
D
K
Y
R
Y
Y
G
R
G
Y
V
R
I
T
D
KDGQVITYEDGSVQDKTVF
L
T
N
E
GANKLG
W
K
L
E
F
L
I
D
E
K
M
F
E
E
E
I
L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
54.43
13%
9
- C4 -
3HPH
1
POL_VILVK
A:
[172-202]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
F
E
S
A
L
A
G
T
L
I
--
T
L
-----
N
I
K
--
R
--
K
-
G
-
G
L
-
G
-----
T
S
P
-
M
D
I
F
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
50.16
40%
3
- C- -
4BY7
-
X:
[77-111]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Y
------
T
E
K
V
R
S
L
Y
S
N
L
K
D
--
K
K
-----
N
L
E
--
L
KA
H
-
V
-
V
E
-
G
-----
K
L
P
-
L
N
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
48.24
22%
-6
- C4 -
3KKS
2
POL_BIV29
A:
[113-144]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
E
T
V
E
A
A
L
S
L
A
L
V
--
S
L
-----
N
K
K
--
R
--
G
-
G
-
I
G
-
G
-----
H
T
P
-
Y
E
I
Y
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
48.15
13%
2
- C3 -
1QA4
1
NEF_HV112
A:
[1-56]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
G
--
K
W
------
S
K
S
S
V
V
G
W
P
A
V
R
E
--
R
M
-----
R
R
A
--
E
--
P
-
A
-
A
D
-
G
-----
V
G
A
-
A
-
S
R
D
L
E
K
H
G
A
I
T
S
S
N
T
A
A
N
N
A
ACAW-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
47.93
40%
0
- C- -
4BXX
-
X:
[77-111]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Y
------
T
E
K
V
R
S
L
Y
S
N
L
K
D
--
K
K
-----
N
L
E
--
L
KA
H
-
V
-
V
E
-
G
-----
K
L
P
-
L
N
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
47.40
40%
-10
- C- -
4BY1
-
X:
[77-111]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Y
------
T
E
K
V
R
S
L
Y
S
N
L
K
D
--
K
K
-----
N
L
E
--
L
KA
H
-
V
-
V
E
--------
L
P
-
L
N
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
46.93
40%
34
- C- -
4BXZ
-
BYE1_YEAST
X:
[301-335]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Y
------
T
E
K
V
R
S
L
Y
S
N
L
K
D
--
K
K
-----
N
L
E
LK
A
--
H
-
V
-
V
E
-
G
-----
K
L
P
-
L
N
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
46.26
23%
-39
- C1 -
1H7D
-
HEM0_MOUSE
A:
[1-49]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
A
AA
M
L
------
L
R
S
C
P
V
L
S
Q
G
P
T
G
--
L
L
G
K
V
A
K
T
Y
Q
--
F
--
L
-
F
-
S
I
-
G
-----
R
C
P
-
I
L
A
T
Q
G
P
T
C
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
43.43
17%
-9
- C4 -
1C6V
-
POL_SIVM1
A:
[171-201]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
E
T
I
V
L
M
A
V
H
--
C
M
-----
N
H
K
--
R
--
R
-
G
-
G
I
-
G
D----
M
T
P
-
A
E
R
L
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
41.08
13%
-18
- C4 -
2NPT
-
MP2K5_HUMAN
A:
[75-106]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
E
M
K
A
M
L
S
Y
Y
Y
S
--
T
V
-----
M
E
Q
--
Q
--
V
-
N
-
G
Q
-
L
-----
I
E
P
-
L
Q
I
F
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
40.97
13%
-19
- C4 -
3OYM
4
POL_FOAMV
A:
[244-273]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
W
Y
D
L
L
P
V
V
Q
L
--
A
L
-----
N
N
T
--
Y
--
S
-
P
-
V
L
-
K
-----
Y
T
P
-
H
Q
L
L
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
40.90
9%
16
- C4 -
1EX4
-
?
A:
[121-154]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
H
L
K
T
A
V
Q
M
A
V
F
--
I
H
-----
N
K
K
--
R
--
K
G
G
-
I
G
-
G
-----
Y
S
A
-
G
E
R
I
V
D
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
39.94
15%
-24
- C4 -
1BCO
-
TNPA_BPMU
A:
[431-469]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
------
A
E
L
F
L
K
T
L
A
E
G
V
A
--
M
F
-----
N
A
R
--
T
--
G
-
R
-
E
T
-
E
MCGGK
L
S
F
-
D
D
V
F
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
39.86
13%
9
- C4 -
1K6Y
-
POL_HV1N5
A:
[170-210]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
H
L
K
T
A
V
Q
M
A
V
F
--
I
H
-----
N
K
K
--
R
--
K
-
G
G
I
G
-
G
-----
Y
S
A
-
G
E
R
I
V
D
I
I
A
T
D
I
Q
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
37.29
11%
4
- C4 -
3F9K
-
POL_HV2RO
A:
[174-202]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
I
V
L
M
A
V
H
--
C
M
-----
N
F
K
--
R
--
R
-
G
-
G
I
G
D
-----
M
T
P
-
S
E
R
L
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
35.03
9%
24
- C4 -
3L3U
1
POL_HV1N5
A:
[121-154]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
H
L
K
T
A
V
Q
M
A
V
F
--
I
H
-----
N
H
K
R-
K
--
G
-
G
-
I
G
-
G
-----
Y
S
A
-
G
E
R
I
V
D
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------