@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA2087: (2016-04-01 )
MANPIKIGIGGPVGAGKTQLIEKVVKRLSKEMSIGVITNDIYTKEDEKILVNSGVLPESRIIGVETGGCPHTAIREDASMNFAAIDELLERHDDIELIFIESGGDNLAATFSPELVDFSIYIIDVAQGEKIPRKGGQGMIKSDFFVINKTDLAPYVGASLEQMAEDTKVFRGKRPFTFTNLKTDEGLDEVIDWIERDTLLKGLS
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20........30----.----.......40.....------...50........60........70........80..-----......90-...--......100...----.----..-.-110...-....120..-----.....130....------------.-----..140........150--......-..160.......170...-----....180.......190.......200..----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAN
P
I
K
I
GIGGPVGA
G
K
T
Q
L
I
E
K
V
V
K
R
L
S
K
E----M----S
I
G
V
I
TNDIYTKED------
E
K
I
L
VNSGVLPES
R
I
I
G
V
ETGGCP
H
T
A
IREDASM
N
F
A
-----
A
I
D
E
L
L
E
--RHD--D
I
E
L
I
F
IESGGD----
N
----
L
A
-
A
-TFSPE
L
-
V
D
F
S
I
Y
I
I
D-----VAQGEKIPRKGG------------Q-----GMIK-S
D
F
F
V
I
NKTD---LAPYV
G
-
A
S
L
E
Q
M
A
E
D
T
K
V
FRGKRP-----
F
T
F
TNLKTDE
G
L
D
E
V
I
D
W
I
E
R
D
T
L
LKGLS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
99.72
61%
-99
- C1 -
4HI0
2
UREG_HELPY
F:
[2-196]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
I
G
V
C
G
P
V
G
S
G
K
T
A
L
I
E
A
L
T
R
H
M
S
K
D
----
Y
----
D
M
A
V
I
T
N
D
I
Y
T
K
E
D
------
A
E
F
M
C
K
N
S
V
M
P
R
E
R
I
I
G
V
E
T
G
G
C
P
H
T
A
I
R
E
D
A
S
M
N
L
E
-----
A
V
E
E
M
H
G
--
R
F
P
--
N
L
E
L
L
L
I
E
S
G
G
D
----
N
----
L
S
-
A
-
T
F
N
P
E
L
-
A
D
F
T
I
F
V
I
D
-----
V
A
E
G
D
K
I
P
R
K
G
G
------------
P
-----
G
I
T
R
-
S
D
L
L
V
I
N
K
I
D
---
L
A
P
Y
V
G
-
A
D
L
K
V
M
E
R
D
S
K
K
M
R
G
E
K
P
-----
F
I
F
T
N
I
R
A
K
E
G
L
D
D
V
I
A
W
I
K
R
N
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
98.91
61%
-99
- C1 -
4HI0
2
UREG_HELPY
E:
[2-196]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
I
G
V
C
G
P
V
G
S
G
K
T
A
L
I
E
A
L
T
R
H
M
S
K
D
----
Y
----
D
M
A
V
I
T
N
D
I
Y
T
K
E
D
------
A
E
F
M
C
K
N
S
V
M
P
R
E
R
I
I
G
V
E
T
G
G
C
P
H
T
A
I
R
E
D
A
S
M
N
L
E
-----
A
V
E
E
M
H
G
--
R
F
P
--
N
L
E
L
L
L
I
E
S
G
G
D
----
N
----
L
S
-
A
-
T
F
N
P
E
L
-
A
D
F
T
I
F
V
I
D
-----
V
A
E
G
D
K
I
P
R
K
G
G
------------
P
-----
G
I
T
R
-
S
D
L
L
V
I
N
K
I
D
---
L
A
P
Y
V
G
-
A
D
L
K
V
M
E
R
D
S
K
K
M
R
G
E
K
P
-----
F
I
F
T
N
I
R
A
K
E
G
L
D
D
V
I
A
W
I
K
R
N
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
75.12
30%
-66
- C1 -
2HF9
4
HYPB_METJA
A:
[16-226]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------KD
I
L
K
A
N
K
R
L
A
D
K
N
R
K
L
L
N
K
H
G
V
V
A
F
D
F
M
G
A
I
G
S
G
K
T
L
L
I
E
K
L
I
D
N
L
K
D
K
----
Y
----
K
I
A
C
I
A
G
D
V
I
A
K
F
D
------
A
E
R
M
E
K
H
G
A
----
K
V
V
P
L
N
T
G
K
E
C
H
L
----
D
A
H
L
V
G
H
-----
A
L
E
D
L
----
N
L
D
--
E
I
D
L
L
F
I
E
N
V
G
N
----
L
----
I
C
-
P
-
A
D
F
D
L
G
-
T
H
K
R
I
V
V
I
S
-----
T
T
E
G
D
D
T
I
E
K
H
P
------------
G
-----
I
M
K
T
-
A
D
L
I
V
I
N
K
I
D
---
L
A
D
A
V
G
-
A
D
I
K
K
M
E
N
D
A
K
R
I
N
P
D
A
E
-----
V
V
L
L
S
L
K
T
M
E
G
F
D
K
V
L
E
F
I
E
K
S
V
K
E
V
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
74.35
27%
-78
- C1 -
2WSM
1
?
A:
[11-213]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------L
A
E
N
K
R
L
A
E
K
N
R
E
A
L
R
E
S
G
T
V
A
V
N
I
M
G
A
I
G
S
G
K
T
L
L
I
E
R
T
I
E
R
I
G
N
E
----
V
----
K
I
G
A
M
L
G
D
V
V
S
K
A
D
------
Y
E
R
V
R
R
F
G
I
----
K
A
E
A
I
S
T
G
K
E
C
H
--------
L
D
A
H
-----
M
I
Y
H
R
L
K
--
K
F
S
--
D
C
D
L
L
L
I
E
N
V
G
N
----
L
----
I
C
-
P
-
V
D
F
D
L
G
-
E
N
Y
R
V
V
M
V
S
-----
V
T
E
G
D
D
V
V
E
K
H
P
------------
E
-----
I
F
R
V
-
A
D
L
I
V
I
N
K
V
A
---
L
A
E
A
V
G
-
A
D
V
E
K
M
K
A
D
A
K
L
I
N
P
R
A
K
-----
I
I
E
M
D
L
K
T
G
K
G
F
E
E
W
I
D
F
L
R
G
I
L
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
72.21
30%
-82
- C1 -
2WSM
1
?
A:
[31-208]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
V
N
I
M
G
A
I
G
S
G
K
T
L
L
I
E
R
T
I
E
R
I
G
N
E
----
V
----
K
I
G
A
M
L
G
D
V
V
S
K
A
D
------
Y
E
R
V
R
R
F
G
I
K
A
E
A
----
I
S
T
G
K
E
C
H
L
----
D
A
H
M
---------
I
Y
H
R
L
K
--
K
F
S
--
D
C
D
L
L
L
I
E
N
V
G
-----
N
----
L
I
-
C
-
P
V
D
F
D
L
G
E
N
Y
R
V
V
M
V
S
-----
V
T
E
G
D
D
V
V
E
K
H
P
------------
E
-----
I
F
R
V
-
A
D
L
I
V
I
N
K
V
A
---
L
A
E
A
V
G
-
A
D
V
E
K
M
K
A
D
A
K
L
I
N
P
R
A
K
-----
I
I
E
M
D
L
K
T
G
K
G
F
E
E
W
I
D
F
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
71.46
30%
-64
- C1 -
2HF9
4
HYPB_METJA
A:
[37-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
V
A
F
D
F
M
G
A
I
G
S
G
K
T
L
L
I
E
K
L
I
D
N
L
K
D
K
----
Y
----
K
I
A
C
I
A
G
D
V
I
A
K
F
D
------
A
E
R
M
E
K
H
G
----
A
K
V
V
P
L
N
T
-
G
K
E
C
H
L
D
---
A
H
L
V
G
H
-----
A
L
E
D
L
N
----
L
D
--
E
I
D
L
L
F
I
E
N
V
G
N
----
L
----
I
C
-
P
A
D
F
D
L
G
--
T
H
K
R
I
V
V
I
S
-----
T
T
E
G
D
D
T
I
E
K
H
P
------------
G
-----
I
M
K
T
-
A
D
L
I
V
I
N
K
I
D
---
L
A
D
A
V
G
-
A
D
I
K
K
M
E
N
D
A
K
R
I
N
P
D
A
E
-----
V
V
L
L
S
L
K
T
M
E
G
F
D
K
V
L
E
F
I
E
K
S
V
K
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
70.77
32%
-65
- C1 -
2HF9
5
HYPB_METJA
B:
[45-220]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
I
G
S
G
K
T
L
L
I
E
K
L
I
D
N
L
K
D
K
----
Y
----
K
I
A
C
I
A
G
D
V
I
A
K
F
D
------
A
E
R
M
E
K
H
G
----
A
K
V
V
P
L
N
T
G
K
E
C
H
L
----
D
A
H
L
V
G
H
-----
A
L
E
D
L
----
N
L
D
--
E
I
D
L
L
F
I
E
N
V
G
-----
N
----
L
I
-
C
-
P
A
D
F
D
L
G
T
H
K
R
I
V
V
I
S
-----
T
T
E
G
D
D
T
I
E
K
H
P
------------
G
-----
I
M
K
T
-
A
D
L
I
V
I
N
K
I
D
---
L
A
D
A
V
G
-
A
D
I
K
K
M
E
N
D
A
K
R
I
N
P
D
A
E
-----
V
V
L
L
S
L
K
T
M
E
G
F
D
K
V
L
E
F
I
E
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
68.93
32%
-65
- C1 -
2HF9
4
HYPB_METJA
A:
[45-220]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
I
G
S
G
K
T
L
L
I
E
K
L
I
D
N
L
K
D
K
----
Y
----
K
I
A
C
I
A
G
D
V
I
A
K
F
D
------
A
E
R
M
E
K
H
G
----
A
K
V
V
P
L
N
T
G
K
E
C
H
L
----
D
A
H
L
V
G
H
-----
A
L
E
D
L
----
N
L
D
--
E
I
D
L
L
F
I
E
N
V
G
-----
N
----
L
I
-
C
-
P
A
D
F
D
L
G
T
H
K
R
I
V
V
I
S
-----
T
T
E
G
D
D
T
I
E
K
H
P
------------
G
-----
I
M
K
T
-
A
D
L
I
V
I
N
K
I
D
---
L
A
D
A
V
G
-
A
D
I
K
K
M
E
N
D
A
K
R
I
N
P
D
A
E
-----
V
V
L
L
S
L
K
T
M
E
G
F
D
K
V
L
E
F
I
E
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
68.73
26%
-72
- C1 -
2WSM
1
?
A:
[28-213]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
T
V
A
V
N
I
M
G
A
I
G
S
G
K
T
L
L
I
E
R
T
I
E
R
I
G
N
E
----
V
----
K
I
G
A
M
L
G
D
V
V
S
K
A
D
------
Y
E
R
V
R
R
F
G
I
K
----
A
E
A
I
S
-
T
G
K
E
C
H
-
L
D
A
--
H
M
I
Y
H
-----
R
L
----
K
--
K
F
S
--
D
C
D
L
L
L
I
E
N
V
G
N
----
L
----
I
C
-
P
V
D
F
D
L
G
--
E
N
Y
R
V
V
M
V
S
-----
V
T
E
G
D
D
V
V
E
K
H
P
------------
E
-----
I
F
R
V
-
A
D
L
I
V
I
N
K
V
A
---
L
A
E
A
V
G
-
A
D
V
E
K
M
K
A
D
A
K
L
I
N
P
R
A
K
-----
I
I
E
M
D
L
K
T
G
K
G
F
E
E
W
I
D
F
L
R
G
I
L
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
68.14
31%
-64
- C1 -
2HF8
5
HYPB_METJA
A:
[45-220]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
I
G
S
G
K
T
L
L
I
E
K
L
I
D
N
L
K
D
K
----
Y
----
K
I
A
C
I
A
G
D
V
I
A
K
F
D
------
A
E
R
M
E
K
H
G
----
A
K
V
V
P
L
N
T
G
K
E
C
H
L
----
D
A
H
L
V
G
H
-----
A
L
E
D
L
----
N
L
D
--
E
I
D
L
L
F
I
E
N
V
G
-----
N
----
L
I
-
C
-
P
A
D
F
D
L
G
T
H
K
R
I
V
V
I
S
-----
T
T
E
G
D
D
T
I
E
K
H
P
------------
G
-----
I
M
K
T
-
A
D
L
I
V
I
N
K
I
D
---
L
A
D
A
V
G
-
A
D
I
K
K
M
E
N
D
A
K
R
I
N
P
D
A
E
-----
V
V
L
L
S
L
K
T
M
E
G
F
D
K
V
L
E
F
I
E
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
62.95
22%
-63
- C1 -
4XC8
4
?
A:
[42-1113]
GPANK
V
R
F
V
T
A
A
S
L
FDGHDAS
I
N
I
M
R
R
I
L
Q
S
Q
GCEVIHLGHNRS
V
Q
E
V
V
T
A
A
L
Q
E
DVQ
G
I
A
I
S
S
YQGG
H
V
E
Y
F
K
Y
M
I
D
L
L
R
E
H
GGEH
I
Q
V
F
G
G
GGGVIV
P
D
E
I
R
E
L
Q
A
Y
GVA
R
I
Y
S
P
E
D
G
Q
R
MG
L
A
G
M
I
T
D
M
A
Q
R
C
DIDLTRYAPTTL
D
T
V
V
A
GD
R
R
A
L
A
Q
L
I
T
A
L
E
N
GKAD
P
E
L
V
S
A
L
H
A
Q
A
K
A
A
A
V
P
V
-
L
G
I
T
G
T
G
G
A
G
K
S
S
L
T
D
E
L
I
R
R
F
R
L
D
----
Q
DDA
L
S
I
A
V
I
S
I
D
P
S
R
R
K
------------
S
G
G
A
L
L
G
D
R
I
R
-
M
N
A
I
N
H
P
N
I
F
M
R
S
L
A
T
R
E
A
G
SEISQ
A
L
P
D
V
I
A
--
A
C
K
A
A
R
F
D
L
V
I
V
E
T
S
G
I
----
G
----
Q
G
-
D
-
A
A
I
V
P
H
-
V
D
L
S
L
Y
V
M
T
-----
P
E
F
G
A
A
S
Q
L
E
K
I
------------
D
-----
M
L
D
F
-
A
D
F
V
A
I
N
K
F
D
RKG
A
Q
D
A
W
R
-
D
V
A
K
Q
V
Q
R
N
R
E
Q
W
H
S
R
A
E
DMP
V
Y
G
T
Q
A
S
R
F
N
D
D
G
V
T
M
L
Y
Q
G
L
V
G
A
L
G
A
R
G
M
S
L
K
PGTLPNLEGRISTGQNVIVPPARSR
Y
L
A
E
L
A
D
T
V
R
A
Y
H
R
R
V
V
A
Q
S
K
L
A
R
E
R
Q
Q
L
R
A
A
H
D
M
L
Q
G
A
GHESA
A
L
E
T
L
A
S
E
R
D
V
S
LG
A
V
E
R
K
L
L
A
M
W
P
Q
M
Q
Q
A
Y
S
GDEYVE
I
R
T
G
L
I
S
T
T
LSG
T
K
I
R
K
V
V
L
P
RFED
E
G
E
I
L
K
W
L
M
R
ENVPGSFPYTAGVFAFKREGEDP
T
R
M
F
A
G
E
G
D
A
F
R
T
N
R
R
F
K
L
V
S
EGMEAK
R
L
S
T
A
F
D
S
V
T
L
Y
GEDPHERPDIYGKVGNS
G
V
S
I
A
T
L
E
D
M
K
V
L
Y
DGFDLTNPS
T
S
V
S
M
T
I
N
GP
A
P
T
I
L
A
M
F
M
N
T
A
I
D
Q
Q
I
D
R
F
R
A
D
N
GRDPT
A
D
E
E
A
K
I
R
A
W
V
L
Q
N
V
R
G
T
V
QAD
I
L
K
E
D
Q
GQNTCIFS
T
E
F
S
L
K
V
M
G
D
I
Q
E
Y
F
V
H
H
QVRNFYSVSISG
Y
H
I
A
E
A
GAN
P
I
S
Q
L
A
F
T
L
A
N
G
F
T
Y
V
E
A
Y
L
A
R
GMHIDDFAPN
L
S
F
F
F
S
N
G
MD
P
E
Y
S
V
L
G
R
V
A
R
R
I
W
A
V
T
M
R
DKYGANDRSQ
K
L
K
Y
H
I
Q
T
S
GRSLHAQEIDF
N
D
I
R
T
T
L
Q
A
L
I
A
I
Y
D
NCN
S
L
H
T
N
A
YDEAITTPT
A
E
S
V
R
R
A
L
A
I
Q
L
I
I
N
REWGVAKCENPNQGS
F
L
I
E
E
L
T
D
L
V
E
E
A
V
L
Q
E
F
E
R
I
A
E
R
GG
V
L
G
A
M
E
T
G
Y
Q
R
G
K
I
Q
E
E
S
L
Y
Y
E
Q
L
K
H
D
GTLPIIGVNTFRNPNGDPRSS
E
D
E
K
Q
S
Q
L
H
R
L
T
E
F
H
G
A
H
QAD
A
E
A
M
L
A
R
L
R
Q
A
V
I
D
NRN
V
F
A
V
L
M
D
A
V
R
V
CS
L
G
Q
I
T
H
A
L
F
E
V
GGQYRRNM
38
HHSearch
59.02
21%
-57
- C1 -
1KY3
2
YPT7_YEAST
A:
[7-179]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
L
K
V
I
I
L
G
D
S
G
V
G
K
T
S
L
M
H
R
Y
V
N
D
K
Y
S
Q
----
Q
----
Y
---
I
G
A
D
F
L
T
-------------
K
E
V
-----------------------------------
T
---
V
D
---
G
D
K
--
V
A
T
M
Q
V
W
D
T
A
----------------
A
F
Y
R
G
--
A
D
C
C
V
L
V
Y
D
-----
V
T
N
A
S
S
F
E
N
I
K
S
W
R
D
E
F
L
V
H
ANVN
S
-----
P
E
T
F
-
P
F
V
I
L
G
N
K
I
D
---
A
E
E
S
K
K
I
V
S
E
K
S
A
Q
E
L
A
K
S
L
-
G
D
I
P
-----
L
F
L
T
S
A
K
N
A
I
N
V
D
T
A
F
E
E
I
A
R
S
A
L
Q
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
57.48
25%
-88
- C1 -
4XC6
4
?
A:
[232-386]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
I
T
G
T
G
G
A
G
K
S
S
L
T
D
E
L
I
R
R
F
R
L
D
Q
DDA
L
----
S
I
A
V
I
S
I
D
P
S
R
R
K
S
GGALLG
D
R
I
R
M
N
A
I
N
H
P
N
I
F
M
R
S
L
A
T
--------
R
E
A
G
S
E
I
S
Q
-----
A
L
P
D
V
I
A
A
C
K
A
A
--
R
F
D
L
V
I
V
E
T
S
G
I
----
G
----
Q
G
D
A
-
A
I
V
P
H
--
V
D
L
S
L
Y
V
M
T
PEFGA
A
S
Q
L
E
K
I
-----------------------
D
M
L
D
F
A
D
F
V
A
I
N
K
F
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
55.63
15%
-51
- C1 -
3X1X
3
RAP1B_RAT
A:
[2-166]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
E
Y
K
L
V
V
L
G
S
G
G
V
G
K
S
A
L
T
V
Q
F
V
Q
G
I
F
V
E
----
K
----
Y
D
P
T
I
E
D
S
-
Y
-------------
R
K
Q
V
-----------------------------------
E
---
V
----
D
A
Q
--
Q
C
M
L
E
I
L
D
T
A
G
T
EQFT
A
----
M
R
-
D
-
L
Y
M
K
N
--
G
Q
G
F
A
L
V
Y
S
-----
I
T
A
Q
S
T
F
N
D
L
Q
D
L
R
E
Q
I
L
R
V
K
---
D
-----
T
D
D
V
-
P
M
I
L
V
G
N
K
C
D
---
L
E
D
E
R
V
-
V
G
K
E
Q
G
Q
N
L
A
R
Q
W
-
S
N
C
A
-----
F
L
E
S
S
A
K
S
K
I
N
V
N
E
I
F
Y
D
L
V
R
Q
I
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
54.11
16%
-48
- C1 -
2HXS
2
RAB28_HUMAN
A:
[4-175]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
Q
L
K
I
V
V
L
G
D
G
A
S
G
K
T
S
L
T
T
C
F
A
Q
E
T
F
G
K
----
Q
----
Y
K
Q
T
I
G
L
D
F
F
L
R
-------------
R
-------------------------------------
I
-
T
L
P
G
---
N
L
--
N
V
T
L
Q
I
W
D
I
G
G
Q
TIGG
K
----
M
L
-
D
-
K
Y
I
Y
G
--
A
Q
G
V
L
L
V
Y
D
-----
I
T
N
Y
Q
S
F
E
N
L
E
D
W
Y
T
V
V
K
------
K
V
S
E
E
S
E
T
Q
P
-
L
V
A
L
V
G
N
K
I
D
---
L
E
H
M
R
T
-
I
K
P
E
K
H
L
R
F
C
Q
E
N
--
G
F
S
-----
S
H
F
V
S
A
K
T
G
D
S
V
F
L
C
F
Q
K
V
A
A
E
I
L
G
I
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
53.96
18%
-61
- C1 -
1Z2A
2
RAB23_MOUSE
A:
[4-167]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
I
K
M
V
V
V
G
N
G
A
V
G
K
S
S
M
I
Q
R
Y
C
K
G
I
F
T
K
----
D
----
Y
K
K
T
I
G
V
D
F
L
E
-------------
R
--
Q
--------------------------------------
I
Q
V
--
N
D
E
--
D
V
R
L
M
L
W
D
T
A
G
Q
----
E
EFDA
I
T
-
K
-
A
Y
Y
R
G
--
A
Q
A
C
V
L
V
F
S
-----
T
T
D
R
E
S
F
E
A
I
S
S
W
R
E
K
V
V
A
-----
E
-----
V
G
D
I
-
P
T
A
L
V
Q
N
K
I
D
---
L
L
D
D
S
C
-
I
K
N
E
E
A
E
G
L
A
K
R
L
--
K
L
R
-----
F
Y
R
T
S
V
K
E
D
L
N
V
S
E
V
F
K
Y
L
A
E
K
H
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
53.49
14%
-99
- C1 -
4NKR
3
?
B:
[1-166]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
P
I
-
V
Q
V
V
G
F
Q
N
S
G
K
T
T
F
I
E
R
I
L
E
K
A
S
E
Q
G---
L
----
N
L
G
C
L
K
H
H
D
R
Y
Q
A
A
------
G
-----------
A
D
V
T
A
V
E
G
A
G
--
V
L
Q
L
T
A
R
R
L
W
D
L
T
-----
R
L
I
E
L
Y
Q
--
F
L
E
---
T
D
C
L
L
I
E
G
F
K
K
----
A
----
P
Y
-
P
-----------
K
V
V
I
L
S
-----
E
K
E
D
L
E
A
L
K
T
----------------------
V
N
-
T
I
A
I
I
Y
R
K
K
E
---
H
M
T
------------------
E
H
Q
G
-----
L
P
I
F
H
A
D
D
P
V
A
V
D
L
V
L
S
Q
L
K
G
E
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
HHSearch
53.05
15%
-46
- C1 -
2A9K
2
RALA_HUMAN
A:
[17-184]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
H
K
V
I
M
V
G
S
G
G
V
G
K
S
A
L
T
L
Q
F
M
Y
D
E
F
V
E
----
D
----
Y
E
P
T
K
A
-
D
S
Y
R
-------------
K
--
K
--------------------------------------
V
V
L
--
D
G
E
--
E
V
Q
I
D
I
L
D
T
A
G
Q
EDY
A
A
----
I
R
-
D
-
N
Y
F
R
S
--
G
E
G
F
L
C
V
F
S
-----
I
T
E
M
E
S
F
A
A
T
A
D
F
R
E
Q
I
L
R
V
K
---
E
-----
D
E
N
V
-
P
F
L
L
V
G
N
K
S
D
---
L
E
D
K
R
Q
-
V
S
V
E
E
A
K
N
R
A
E
Q
W
--
N
V
N
-----
Y
V
E
T
S
A
K
T
R
A
N
V
D
K
V
F
F
D
L
M
R
E
I
R
A
R
K
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
HHSearch
53.01
15%
-63
- C1 -
2GF0
2
DIRA1_HUMAN
A:
[6-174]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
D
Y
R
V
V
V
F
G
A
G
G
V
G
K
S
S
L
V
L
R
F
V
K
G
T
F
R
D
----
T
----
Y
I
P
T
I
E
D
T
Y
R
Q
---------------
V
-
I
------------------------------------
S
C
----
D
K
S
--
V
C
T
L
Q
I
T
D
T
T
G
S
----
H
QF
P
A
M
Q
-
R
-
L
S
I
S
K
--
G
H
A
F
I
L
V
F
S
-----
V
T
S
K
Q
S
L
E
E
L
G
P
I
Y
K
L
I
V
Q
I
K
G--
S
-----
V
E
D
I
-
P
V
M
L
V
G
N
K
C
D
---
E
T
Q
R
E
--
V
D
T
R
E
A
Q
A
V
A
Q
E
--
W
K
C
A
-----
F
M
E
T
S
A
K
M
N
Y
N
V
K
E
L
F
Q
E
L
L
T
L
E
T
R
R
N
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
52.02
16%
-39
- C1 -
3BC1
2
RB27A_MOUSE
A:
[10-187]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
I
K
F
L
A
L
G
D
S
G
V
G
K
T
S
V
L
Y
Q
Y
T
D
G
K
F
N
S
----
K
----
F
I
T
T
V
G
I
D
F
R
E
K
R
-------------
V
V
Y
R
A
N
------
G
P
----
D
G
----------------
A
---
V
-
G
--
R
G
Q
--
R
I
H
L
Q
L
W
D
T
A
G
L
ERF
R
S
----
L
T
-
T
-
A
F
F
R
D
--
A
M
G
F
L
L
L
F
D
-----
L
T
N
E
Q
S
F
L
N
V
R
N
W
I
S
Q
L
Q
M
HA---
Y
-----
S
E
N
P
-
D
I
V
L
C
G
N
K
S
D
---
L
E
D
Q
R
A
-
V
K
E
E
E
A
R
E
L
A
E
K
Y
--
G
I
P
-----
Y
F
E
T
S
A
A
N
G
T
N
I
S
H
A
I
E
M
L
L
D
L
I
M
K
R
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------