@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA2097: (2016-04-01 )
MKKLVTATTLTAGIGTALVGQAHHADAAENYTNYNNYNYNTTQTTTTTTTTTTTSSISHSGNLYTAGQCTWYVYDKVGGEIGSTWGNANNWAAAAQGAGFTVNHTPSKGAILQSSEGPFGHVAYVESVNSDGSVTISEMNYSGGPFSVSSRTISASEAGNYNYIHI
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20..--......30........40........50......----..60.....---..-------.70....-----....---80........90.....--------.--------..100----.-----..-----.....110...-------------.------------.---..---120.......130.......140....---...150--........160....----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKK
L
V
T
A
T
T
LT
A
G
I
G
T
A
L
VGQAH--HAD
A
A
ENYTNYNN
Y
N
YN
T
T
Q
T
T
T
T
T
T
T
T
T
T
T
SSI----SHSG
N
L
Y
T
A
---
G
Q
-------
C
T
W
Y
V
YD-----KVGG---EIGSTWGNANNWAAAAQ--------G--------A
G
F
T
-----
V
-----NH-----TPSK
G
A
I
LQSS-------------E------------G---PF---
G
H
V
A
Y
V
E
SVNSDG
S
V
T
I
S
E
MNYSGG
P
F
---
S
V
S
S
R
---
T
I
SASEAGNYNYIHI----
1
PsiBlast_PDB
95.34
100%
-125
- C3 -
2LRJ
-
?
A:
[2-113]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
I
----
S
H
S
G
N
L
Y
T
A
---
G
Q
-------
C
T
W
Y
V
Y
D
-----
K
V
G
G
---
E
I
G
S
T
W
G
N
A
N
N
W
A
A
A
A
Q
--------
G
--------
A
G
F
T
-----
V
-----
N
H
-----
T
P
S
K
G
A
I
L
Q
S
S
-------------
E
------------
G
---
P
F
---
G
H
V
A
Y
V
E
S
V
N
S
D
G
S
V
T
I
S
E
M
N
Y
S
G
G
P
F
---
S
V
S
S
R
---
T
I
S
A
S
E
A
G
N
Y
N
Y
I
H
I
----
2
PsiBlast_PDB
91.39
66%
-121
- C3 -
2K3A
-
?
A:
[1-154]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
K
L
V
T
A
T
T
L
T
A
G
I
G
A
A
I
V
G
L
D
H
G
N
E
A
D
A
A
E
Q
--------------
T
Q
P
T
N
Q
S
T
T
Q
S
T
S
----
G
S
S
A
N
L
Y
T
A
---
G
Q
-------
C
T
W
Y
V
Y
D
-----
K
V
G
G
---
N
I
G
S
T
W
G
N
A
N
N
W
A
S
A
A
S
--------
S
--------
A
G
Y
T
-----
V
-----
N
N
-----
S
P
E
A
G
S
I
L
Q
S
T
-------------
A
------------
G
---
G
Y
---
G
H
V
A
Y
V
E
N
V
N
S
D
G
S
V
E
V
S
E
M
N
Y
N
G
G
P
F
---
S
V
S
E
R
---
T
I
S
A
G
E
A
S
S
Y
N
Y
I
H
L
----
8
HHSearch
91.36
69%
-121
- C3 -
2K3A
-
?
A:
[1-154]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
K
L
V
T
A
T
T
L
T
A
G
I
G
A
A
I
V
G
L
D
H
--
G
N
E
A
D
A
A
E
Q
T
Q
P
-
T
N
Q
-----------
S
T
T
Q
S
T
S
----
G
S
S
A
N
L
Y
T
A
---
G
Q
-------
C
T
W
Y
V
Y
D
-----
K
V
G
G
---
N
I
G
S
T
W
G
N
A
N
N
W
A
S
A
A
S
--------
S
--------
A
G
Y
T
-----
V
-----
N
N
-----
S
P
E
A
G
S
I
L
Q
S
T
-------------
A
------------
G
---
G
Y
---
G
H
V
A
Y
V
E
N
V
N
S
D
G
S
V
E
V
S
E
M
N
Y
N
G
G
P
F
---
S
V
S
E
R
---
T
I
S
A
G
E
A
S
S
Y
N
Y
I
H
L
----
7
PsiBlast_CBE
66.40
42%
-99
- C3 -
4CGK
4
?
B:
[287-365]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
P
I
---
G
E
-------
C
T
W
G
V
-
K
-----
T
L
A
P
---
W
A
G
D
Y
W
G
N
G
A
Q
W
A
T
S
A
A
--------
A
--------
A
G
F
R
-----
T
-----
G
S
-----
T
P
Q
V
G
A
I
A
C
W
N
-------------
D
------------
G
---
G
Y
---
G
H
V
A
V
V
T
A
V
E
S
T
T
R
I
Q
V
S
E
S
N
Y
A
G
---------------------------------
24
Fugue
65.96
27%
-77
- C3 -
4CGK
7
?
A:
[42-392]
SNLT
A
Q
Q
Q
E
A
Q
K
Q
V
D
Q
I
Q
E
Q
V
S
A
I
Q
A
E
Q
S
N
L
Q
A
E
N
D
R
L
Q
A
E
S
K
K
L
E
G
E
I
T
E
L
S
K
N
I
V
S
R
N
Q
S
L
E
K
Q
A
R
S
A
Q
T
N
G
A
V
T
S
Y
I
N
T
I
V
NSKSITEAIS
R
V
A
A
M
S
E
I
V
S
A
N
N
K
M
L
E
Q
Q
K
A
D
K
K
A
I
S
E
K
Q
V
A
N
N
D
A
I
N
T
V
I
A
N
Q
Q
K
L
A
D
D
A
Q
A
L
T
T
K
Q
A
E
L
K
A
A
E
L
S
L
A
A
E
K
ATA
E
G
E
K
A
S
L
L
E
Q
K
A
A
A
E
A
E
A
R
A
A
A
V
A
E
A
A
Y
K
E
K
R
--
A
S
Q
Q
Q
S
V
L
A
S
A
N
T
N
L
T
A
Q
V
Q
A
V
S
E
S
A
A
A
P
V
R
A
K
V
R
P
T
Y
S
T
N
A
S
S
Y
P
I
---
G
E
-------
C
T
W
G
V
K
T
-----
L
A
P
W
----
A
G
D
Y
W
G
N
G
A
Q
W
A
T
S
A
A
--------
A
--------
A
G
F
R
-----
T
-----
G
S
-----
T
P
Q
V
G
A
I
A
C
W
N
-------------
D
------------
G
---
G
Y
---
G
H
V
A
V
V
T
A
V
E
S
T
T
R
I
Q
V
S
E
S
N
Y
A
G
N
R
T
---
I
G
N
H
R
GWF
N
P
T
T
T
S
E
G
F
V
T
Y
I
Y
A
D---
3
PsiBlast_PDB
65.43
42%
-96
- C3 -
4CGK
1
?
A:
[287-365]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
P
I
---
G
E
-------
C
T
W
G
V
-
K
-----
T
L
A
P
---
W
A
G
D
Y
W
G
N
G
A
Q
W
A
T
S
A
A
--------
A
--------
A
G
F
R
-----
T
-----
G
S
-----
T
P
Q
V
G
A
I
A
C
W
N
-------------
D
------------
G
---
G
Y
---
G
H
V
A
V
V
T
A
V
E
S
T
T
R
I
Q
V
S
E
S
N
Y
A
G
---------------------------------
26
Fugue
58.81
23%
-51
- C3 -
4CT3
9
?
A:
[2-165]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
T
----------------
Q
A
E
I
N
K
R
L
D
A
Y
A
K
G
T
V
D
S
P
Y
R
V
K
K
A
T
S
Y
D
P
S
F
G
V
----
M
E
A
G
A
I
D
A
D
---
G
Y
YHAQQ
D
L
I
T
D
Y
V
L
W
-----
L
T
D
N
---
K
V
-
R
T
W
G
N
A
K
D
Q
I
K
Q
S
Y
--------
G
--------
T
G
F
K
-----
I
-----
H
E
NKPS
T
V
P
K
K
G
W
I
A
V
F
T
-------------
S
------------
G
---
S
Y
EQW
G
H
I
G
I
V
Y
D
G
G
N
T
S
T
F
T
I
L
E
Q
N
W
N
G
Y
A
N
---
K
K
P
T
K
---
R
V
D
-
N
Y
Y
G
L
T
H
F
I
E
I
P
V
K
A
25
Fugue
56.50
21%
-44
- C3 -
4OLK
2
?
A:
[4-167]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
K
--
T
Q
A
E
I
N
K
R
L
D
A
Y
A
K
G
T
V
D
--
S
P
Y
R
I
K
K
A
T
S
Y
D
P
S
F
---------
G
V
M
E
A
G
A
I
D
A
----
D
G
Y
Y
H
A
Q
C
Q
---
D
L
-------
I
T
D
Y
V
L
W
-----
L
T
D
N
---
K
V
-
R
T
W
G
N
A
K
D
Q
I
K
Q
S
Y
--------
G
--------
T
G
F
K
-----
I
-----
H
E
N
K
PS
T
V
P
K
K
G
W
I
A
V
F
T
-------------
S
------------
G
SYQ
Q
W
---
G
H
I
G
I
V
Y
D
G
G
N
T
S
T
F
T
I
L
E
Q
N
W
N
G
Y
A
N
---
K
-
K
P
T
---
K
R
V
D
N
Y
Y
G
L
T
H
F
I
E
I
P
V
K-
10
HHSearch
56.03
20%
-85
- C3 -
2IO8
-
GSP_ECOLI
A:
[51-155]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
M
G
H
K
---
W
Q
-------
C
V
E
F
A
R
R
-----
F
L
F
L
N
YG
V
V
F
T
D
V
G
M
A
W
E
I
F
S
L
R
F
L
R
E
VVND
N
I
--------
L
P
L
Q
-----
A
F
P
NGS
P
R
-----
A
P
V
A
G
A
L
L
I
W
D
-------------
K
GGEF--------
K
---
D
T
---
G
H
V
A
I
I
T
Q
L
H
G
-
N
K
V
R
I
A
E
Q
N
V
I
H
---------------------------------
9
HHSearch
55.32
19%
-73
- C3 -
3A2Z
-
GSP_ECOLI
A:
[51-169]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
M
G
H
K
---
W
Q
-------
C
V
E
F
A
R
R
-----
F
L
F
L
N
YG
V
V
F
T
D
V
G
M
A
W
E
I
F
S
L
R
F
--------
L
R
EVVND
N
I
L
P
L
Q
A
F
P
NG
S
-----
P
R
-----
A
P
V
A
G
A
L
L
I
W
D
-------------
K
GGEF--------
K
---
D
T
---
G
H
V
A
I
I
T
Q
L
H
G
-
N
K
V
R
I
A
E
Q
N
V
I
H
S
P
L
PQG
Q
Q
W
T
R
---
E
L
E
M
V
V
-------------
11
HHSearch
50.49
17%
-90
- C3 -
2VOB
-
?
A:
[50-201]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
F
F
G
F
K
---
Y
Q
-------
C
V
E
F
A
R
R
-----
W
L
L
V
R
KG
L
L
L
P
D
V
N
W
A
C
H
I
F
Q
L
K
E
VRDAATT
E
S
--------
F
A
V
L
-----
Q
V
R
N
GT
T
T
-----
K
P
E
A
D
A
L
L
V
Y
P
-------------
S
TDA---------
N
---
P
V
---
G
H
V
G
T
I
T
E
V
G
D
-
D
Y
V
C
V
A
D
Q
N
Y
R
F
---------------------------------
6
PsiBlast_PDB
50.16
30%
-65
- C3 -
4OLK
1
?
A:
[74-142]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
W
G
N
A
K
D
Q
I
K
Q
S
Y
--------
G
--------
T
G
F
K
-----
I
-----
H
E
N
K
PS
T
V
P
K
K
G
W
I
A
V
F
T
-------------
S
------------
G
---
S
Y
QQW
G
H
I
G
I
V
Y
D
G
G
N
T
S
T
F
T
I
L
E
Q
N
W
N
G
---------------------------------
4
PsiBlast_PDB
49.27
30%
-63
- C3 -
4CSH
3
?
A:
[71-139]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
W
G
N
A
K
D
Q
I
K
Q
S
Y
--------
G
--------
T
G
F
K
-----
I
-----
H
E
NKPS
T
V
P
K
K
G
W
I
A
V
F
T
-------------
S
------------
G
---
S
Y
EQW
G
H
I
G
I
V
Y
D
G
G
N
T
S
T
F
T
I
L
E
Q
N
W
N
G
---------------------------------
5
PsiBlast_PDB
46.57
30%
-60
- C3 -
4CT3
5
?
A:
[71-139]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
W
G
N
A
K
D
Q
I
K
Q
S
Y
--------
G
--------
T
G
F
K
-----
I
-----
H
E
NKPS
T
V
P
K
K
G
W
I
A
V
F
T
-------------
S
------------
G
---
S
Y
EQW
G
H
I
G
I
V
Y
D
G
G
N
T
S
T
F
T
I
L
E
Q
N
W
N
G
---------------------------------
32
Fugue
42.06
12%
-37
- C3 -
3P8B
9
SPT5_PYRFU
B:
[2-148]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
K
I
F
A
V
R
V
T
H
G
Q
E
E
T
T
A
K
L
I
Y
--
S
K
V
R
T
Y
N
L
P
I
Y
-----------------
A
I
L
A
P
S
----
R
V
K
G
Y
I
F
V
E
A
PN
K
G
-------
V
V
D
E
A
I
R
-----
G
I
R
H
---
A
R
G
V
L
P
G
E
V
P
F
K
E
I
E
H
F
--------
L
--------
E
E
K
P
-----
A
-----
V
S
-----
G
L
E
P
G
D
L
V
E
V
I
-------------
A
------------
G
---
P
F
K--
G
Q
K
A
K
V
V
K
I
D
E
S
K
D
E
V
V
V
Q
F
I
D
A
I
V
P
------
I
P
V
---
T
I
K
G
D
Y
V
R
L
I
S
K
L
------
31
Fugue
31.48
9%
-13
- C1 -
4QTT
3
TR112_YEAST
A:
[1-132]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
F
L
T
T
N
F
L
K
C
S
V
K
A
C
D
T
S
N
D
N
--
F
P
--------------
L
Q
Y
D
G
S
K
C
Q
L
V
Q
D
E
S
I
E
F
----
N
P
E
F
L
L
N
I
V
---
D
R
-------
V
D
W
P
A
V
L
-----
T
V
A
A
---
E
L
G
N
N
---------
A
L
P
--------
P
--------
T
K
P
S
-----
F
-----
P
S
-----
S
I
Q
E
L
T
D
D
D
M
A
-------------
I
------------
L
---
N
D
---
L
H
T
L
L
L
Q
T
S
I
A
E
G
E
M
K
C
R
N
---
C
G
H
I
Y
---
Y
I
K
N
G
---
I
P
N
L
L
L
P
P
-----------
15
HHSearch
30.70
18%
-60
- C3 -
2IF6
-
?
A:
[4-50]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
P
Q
T
G
D
I
I
F
Q
I
S
RSSQ
S
K
A
I
Q
L
A
T
H
------------
S
---
D
Y
---
S
H
T
G
M
L
V
M
R
N
--
K
K
P
Y
V
F
E
A
V
------------------------------------
18
HHSearch
30.58
22%
-62
- C3 -
3KW0
2
?
A:
[37-91]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
-----
V
L
K
T
G
D
I
F
L
C
S
G
NY
L
V
S
K
L
I
K
K
V
S
E
------------
S
---
M
F
---
S
H
T
G
I
I
V
K
W
G
--
E
H
T
L
I
M
E
S
V
E
-----------------------------------
28
Fugue
29.37
14%
-30
- C4 -
2K3D
-
?
A:
[12-98]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
--
F
N
E
Q
K
E
K
V
T
L
Y
L
K
H
N
I
P
D
F
N
T
V
T
F
T
N
E
E
F
N
P
I
G
I
----
S
I
D
G
Y
I
N
N
D
---
K
N
-------
L
S
F
T
A
G
K
DVK
I
F
S
S
S
E
---
E
L
D
K
M
F
Q
E
P
R
K
G
Y
D
E
I
L
--------
E
--------
H
H
H
H
-----
H
-----
H
-------------------------------------------------------------------------------------------------------------
22
HHSearch
29.14
11%
-61
* C3 *
2IM9
-
?
A:
[262-310]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-----
Q
I
P
N
G
A
V
I
E
I
I
-------------
R
PNWDLRQQIG
T
E
L
---
D
I
---
S
H
L
G
F
A
I
W
I
N
--
N
E
L
F
F
R
Q
A
S
------------------------------------