@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA2257: (2016-04-02 )
MNNFNNEIKLILQQYLEKFEAHYERVLQDDQYIEALETLMDDYSEFILNPIYEQQFNAWRDVEEKAQLIKSLQYITAQCVKQVEVIRARRLLDGQASTTGYFDNIEHCIDEEFGQCSITSNDKLLLVGSGAYPMTLIQVAKETGASVIGIDIDPQAVDLGRRIVNVLAPNEDITITDQKVSELKDIKDVTHIIFSSTIPLKYSILEELYDLTNENVVVAMRFGDGIKAIFNYPSQETAEDKWQCVNKHMRPQQIFDIALYKKAAIKVGITDV
Atome Classification :
(20 SA)
-------------------------.........10........20.......------.30...--.....40........50.........60........70-........80........90..---.-----.-----.-...100.......110.......120---.....---.--.130.......140...--.-.....150.......160......--.170.----------......180..-----------------.-..-..190..-.-..----.-----.200--.....-...210----.....-...220--.-------------..------------.....230...---------....-240.---......250.-.---..-...260..--.....270--------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------MNN
F
N
N
E
I
K
L
I
L
Q
Q
Y
L
E
K
F
E
A
H
Y
E
R
V
LQ------D
D
Q
Y
I
E
--
A
L
E
T
L
M
D
D
Y
S
E
F
I
L
N
P
-
I
Y
E
Q
Q
F
N
A
W
R
D
V
E
E
K
A
Q
L
I
K
S
-
L
Q
Y
I
T
A
Q
C
V
K
Q
V
E
V
I
R
A
R
R
LLD---G-----Q-----A-STTG
Y
F
D
N
I
E
H
C
I
D
E
E
FGQCSITSN
D
---
K
L
L
L
V---G--SGAY
P
M
T
L
I
Q
V
A
--
K
ET--G-
A
S
V
I
G
I
DID
P
Q
A
V
D
L
G
R
R
I
V
N
V
LA--PNE
D
I
----------
T
I
T
D
Q
K
V
S
E
L
K
-----------------
D
-
I
K
-
D
V
T
H
I
I
F-S-ST----I-----
P
L
K
---
Y
S
I
L
E
-
E
L
Y
D
L-----TNE
N
V
-
V
V
A
M
R---F-------------GD------------
G
I
K
A
I
FNYPSQ---------ET
A
E
-
D
K
W
Q
---
C
V
N
KHM
R
P
Q
Q
-
I
---
F
D
-
I
A
L
Y
K
K
A
A
--
I
K
VGITDV--------------------------
35
HHSearch
82.70
13%
-101
- C3 -
3FPF
2
?
A:
[4-265]
------------------------------
Y
I
Y
W
D
K
I
K
R
I
A
S
R
L
E
G
M
N
Y
H
F
--------
D
E
M
D
T
S
--
G
V
M
P
L
L
D
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E
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A
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A
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D
A
E
M
N
H
A
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S
L
-
I
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K
F
Y
V
N
L
G
M
K
L
E
M
E
K
A
Q
E
V
I
E
---
S
-----
D
S
P
W
E
T
L
-
R
S
F
Y
F
Y
P
R
Y
L
E
L
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K
N
E
A
A
L
G
R
F
R
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G
E
---
R
A
V
F
I
---
G
--
G
G
P
L
P
L
T
G
I
L
L
S
--
H
V
Y
--
G
-
M
R
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N
V
V
E
I
E
P
D
I
A
E
L
S
R
K
V
I
E
G
L
G
--
V
D
-
G
V
----------
N
V
I
T
G
D
E
T
V
I
D
-------------------
G
L
-
E
F
D
V
L
M
V
-
A
-
A
L
----
A
-----
E
P
K
---
R
R
V
F
R
-
N
I
H
R
Y
-----
V
D
T
E
T
-
R
I
I
Y
R
---
T
-------------
Y
T
------------
G
M
R
A
I
L
-
Y
A
P
V
---------
S
D
D
D
I
T
G
F
R
---
R
A
G
-
V
V
L
P
S
G
K
V
---
N
N
T
S
V
L
V
F
K
C
P
------------------------------------
25
Fugue
80.96
12%
-90
- C3 -
3FPF
2
?
A:
[2-265]
------------------------S
C
Y
I
Y
W
D
K
I
K
R
I
A
S
R
L
E
G
M
N
Y
------
H
F
------
D
E
M
D
T
S
--
G
V
M
P
L
L
D
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A
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S
T
I
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F
E
S
A
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D
D
A
E
M
N
H
A
L
S
L
-
I
R
K
F
Y
V
N
L
G
M
K
L
E
M
E
K
A
Q
E
V
I
E
---
S
DS
P
W
E
T
-----
L
-
R
S
F
Y
F
Y
P
R
Y
L
E
L
L
K
N
E
A
A
L
G
R
F
R
R
G
E
---
R
A
V
F
I
---
G
--
G
G
P
L
P
L
T
G
I
L
L
S
--
H
V
Y
--
G
-
M
R
V
N
V
V
E
I
E
P
D
I
A
E
L
S
R
K
V
I
E
G
L
G
--
V
-
D
G
V
----------
N
V
I
T
G
D
E
T
V
I
D
-----------------
G
--
L
-
E
F
D
V
L
M
V
-
A
-
A
L
----
A
-----
E
P
K
---
R
R
V
F
R
-
N
I
H
R
Y
-----
V
D
T
E
T
-
R
I
I
Y
R
---
T
-------------
Y
T
------------
G
M
R
A
I
L
Y
A
P
V
S
---------
D
D
D
I
-
T
G
F
R
---
R
A
G
V
V
L
P
S
G
K
-
V
---
N
N
-
T
S
V
L
V
F
K
C
--
P
---------------------------------
32
Fugue
66.09
13%
-76
- C3 -
1I9G
1
TRMI_MYCTU
A:
[4-267]
-------------------------
T
G
P
F
S
I
G
E
R
V
Q
L
T
D
A
K
G
R
---
R
Y
T
M
S
L
T
------
P
G
A
E
F
H
--
T
------
H
R
G
S
I
A
H
D
A
-
V
I
G
L
E
Q
G
----------------
S
V
V
K
S
S
N
G
A
L
F
L
V
L
R
P
L
L
V
D
Y
---
V
-----
M
-----
S
-
M
P
R
G
P
Q
V
I
Y
P
K
D
A
A
Q
I
V
H
E
G
D
I
F
P
G
A
---
R
V
L
E
A
---
G
AG
S
G
A
L
T
L
S
L
L
R
A
V
--
G
P
A
--
G
--
Q
V
I
S
Y
E
Q
R
A
D
H
A
E
H
A
R
R
N
V
S
G
C
Y
GQ
P
P
D
N
W
----------
R
L
V
V
S
D
L
A
D
S
E
-----------------
L
-
P
D
-
G
S
V
D
R
A
V
-
L
-
D
-----
M
-----
L
A
P
---
W
E
V
L
D
-
A
V
S
R
L
-----
L
V
A
G
G
-
V
L
M
V
Y
V
AT
V
-------------
T
Q
------------
L
S
R
I
V
E
A
L
R
A
K
QCWTE
P
R
A
W
E
T
L
Q
-
R
G
W
N
---
V
V
G
L
A
V
R
P
Q
H
-
S
MRG
H
T
-
A
F
L
V
A
T
R
R
--
L
A
P
G
A
V
A
---------------------------
28
Fugue
64.39
19%
-60
- C3 -
4QNU
3
CMOB_ECOK1
A:
[1-323]
-------------------------
M
I
D
F
G
N
F
Y
S
L
I
A
K
N
H
L
S
H
W
L
E
T
L
P
A
Q
I
A
------
N
W
Q
R
E
Q
QH
G
L
F
K
Q
W
S
N
A
V
E
F
-
L
P
E
-
I
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P
Y
R
L
D
L
L
H
S
V
-----
T
A
E
S
-
E
E
P
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S
A
G
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R
I
E
T
L
-
M
R
N
L
M
P
WRK
G
-----
P
-----
F
-
S
L
Y
G
V
N
I
D
T
E
W
R
S
D
W
K
W
D
R
V
L
P
H
L
S
D
LTG
R
T
I
L
D
V
GC
G
--
S
G
Y
H
M
W
R
M
I
G
-----
A
G
--
A
-
H
L
A
V
G
I
D
P
T
Q
L
F
L
C
Q
F
E
A
V
R
K
L
L
G
--
N
D
Q
R
A
----------
H
L
L
P
L
G
I
E
Q
L
P
-----------------
A
-
L
K
-
A
F
D
T
V
F
S
-
M
-
G
V
----
L
-----
Y
H
R
---
R
S
P
L
E
-
H
L
W
Q
L
K
D
Q
L-
V
N
E
G
E
-
L
V
L
E
T
---
L
V
I
D
----------
G
D
EN
T
V
L
V
P
G
DRYA
Q
M
R
N
V
Y
F
I
P
S
A
---------
L
A
L
K
-
N
W
L
K
K
C
G
F
V
D
I
R
I
A
D
V
S
-
V
---
T
T
-
T
E
E
Q
R
R
T
E
WM
V
T
E
S
L
A
D
F
LDPHDPGKTVEGYP
A
P
K
R
A
V
L
I
A
R
K
P
41
HHSearch
60.21
12%
-113
- C3 -
2FK8
1
MMAA4_MYCTU
A:
[87-195]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
K
P
G
M
---
T
L
L
D
I
---
G
--
C
G
W
-
G
T
T
M
R
R
A
V
--
E
R
F
--
D
-
V
N
V
I
G
L
T
L
S
K
N
Q
H
A
R
C
E
Q
V
L
A
S
I
D
--
T
N
R
S
R
----------
Q
V
L
L
Q
G
W
E
D
F
--------------------
A
E
-
P
V
D
R
I
V
S
-
I
-
E
A
----
F
EHFGH
E
N
Y
---
D
D
F
F
K
-
R
C
F
N
I
-----
M
P
A
D
G
-
R
M
T
V
Q
---
S
-------------
S
-----------------------------------------------------------------------------------------------------------
49
HHSearch
60.10
19%
-115
- C3 -
3UJC
1
?
A:
[49-160]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
I
E
L
N
E
N
S
---
K
V
L
D
I
---
G
--
S
G
L
-
G
G
G
C
M
Y
I
N
--
E
K
Y
--
G
-
A
H
T
H
G
I
D
I
C
S
N
I
V
N
M
A
N
E
R
V
S
G
N
-----
N
K
I
----------
I
F
E
A
N
D
I
L
T
K
E
-----------------
F
-
P
E
-
N
N
F
D
L
I
Y
-
S
R
D
A
----
I
LALS
L
E
N
K
---
N
K
L
F
Q
-
K
C
Y
K
W
-----
L
K
P
T
G
-
T
L
L
I
T
---
D
-------------
Y
-----------------------------------------------------------------------------------------------------------
37
HHSearch
57.67
18%
-78
- C3 -
2O57
-
?
A:
[80-188]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
R
Q
A
---
K
G
L
D
L
---
G
--
A
G
Y
-
G
G
A
A
R
F
L
V
--
R
K
F
--
G
-
V
S
I
D
C
L
N
I
A
P
V
Q
N
K
R
N
E
E
Y
N
N
Q
A
G
--
L
A
D
N
I
----------
T
V
K
Y
G
S
F
L
E
I
P
-----------------
C
-
E
D
-
N
S
Y
D
F
I
W
-
S
-
Q
D
AFLH
S
-----
P
D
K
---
L
K
V
F
Q
-
E
C
A
R
V
-----
L
K
P
R
G
-
V
M
A
I
T
---
D
-------------
P
-----------------------------------------------------------------------------------------------------------
40
HHSearch
57.38
18%
-114
* C3 *
3BUS
1
REBMT_NOCAE
A:
[57-167]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
V
R
S
G
D
---
R
V
L
D
V
---
G
--
C
G
I
-
G
K
P
A
V
R
L
A
--
T
A
R
--
D
-
V
R
V
T
G
I
S
I
S
R
P
Q
V
N
Q
A
N
A
R
A
T
A
A
G
--
L
A
N
R
V
----------
T
F
S
Y
A
D
A
M
D
L
P
-----------------
F
-
E
D
A
S
F
D
A
V
W
A
-
L
-
E
S
----
L
HHM--
P
D
R
---
G
R
A
L
R
-
E
M
A
R
V
-----
L
R
P
G
G
-
T
V
A
I
A
---
D
-------------
F
-----------------------------------------------------------------------------------------------------------
34
Fugue
56.92
11%
-74
- C3 -
1UFK
-
PRMA_THET8
A:
[1-254]
--------------------M
W
V
Y
R
L
K
G
T
L
E
A
L
D
P
I
L
P
G
L
F
D
--
G
G
A
R
G
L
W
E
R
------
E
G
E
V
W
A
--
F
F
P
A
P
V
D
L
P
Y
E
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E
E
-
V
G
D
E
D
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A
W
R
R
D
L
K
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A
L
A
P
P
-
F
V
V
L
A
P
W
H
T
W
E
G
A
E
I
P
L
V
I
E
P
G
---
H
-----
H
-----
E
-
T
T
R
L
A
L
K
A
L
A
R
H
L
---------
R
P
G
D
---
K
V
L
D
L
---
G
--
T
G
--
S
G
V
L
A
I
A
A
--
E
K
L
--
G
-
G
K
A
L
G
V
D
I
D
P
M
V
L
P
Q
A
E
A
--
N
A
K
R
--
N
G
V
R
P
----------
R
F
L
E
G
S
L
E
A
A
L
-----------------
P
-
F
G
-
P
F
D
L
L
V
A
-
N
-
L
Y
----
A
-----
E
L
H
---
A
A
L
A
P
-
R
Y
R
E
A
-----
L
V
P
G
G
-
R
A
L
L
T
-------------------------------
G
I
L
--------------------
K
-
D
R
A
P
---
L
V
R
E
A
M
A
G
A
G
-
F
---
R
P
-
L
E
E
A
A
E
G
E
--
W
V
L
L
A
Y
G
R
--------------------------
38
HHSearch
56.45
17%
-97
- C3 -
3DLC
3
?
A:
[44-149]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
---
T
C
I
D
I
---
G
--
S
G
P
-
G
A
L
S
I
A
L
A
--
K
Q
S
--
D
-
F
S
I
R
A
L
D
F
S
K
H
M
N
E
I
A
L
K
N
I
A
D
A
N
--
L
N
D
R
I
----------
Q
I
V
Q
G
D
V
H
N
I
P
-----------------
I
-
E
D
-
N
Y
A
D
L
I
V
-
S
-
R
G
SVFF
W
-----
E
D
V
---
A
T
A
F
R
-
E
I
Y
R
I
-----
L
K
S
G
G
-
K
T
Y
I
G
---
G
-------------
G
-----------------------------------------------------------------------------------------------------------
53
HHSearch
56.39
18%
-94
- C3 -
3OCJ
3
?
A:
[117-228]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
P
G
C
---
V
V
A
S
V
---
P
--
C
G
W
-
M
S
E
L
L
A
L
D
YS
A
C
P
--
G
-
V
Q
L
V
G
I
D
Y
D
P
E
A
L
D
G
A
T
R
L
A
A
G
H
A
--
L
A
G
Q
I
----------
T
L
H
R
Q
D
A
W
K
L
D
-----------------
T
-
R
E
-
G
Y
D
L
L
T
S
-
N
-
G
L
----
N
IYE--
P
D
D
A
R
V
T
E
L
Y
R
-
R
F
W
Q
A
-----
L
K
P
G
G
-
A
L
V
T
S
---
F
-------------
L
-----------------------------------------------------------------------------------------------------------
36
HHSearch
53.40
13%
-76
- C3 -
3VC1
4
GPPMT_STRCO
A:
[116-222]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
D
D
---
T
L
V
D
A
---
G
--
C
G
R
-
G
G
S
M
V
M
A
H
--
R
R
F
--
G
-
S
R
V
E
G
V
T
L
S
A
A
Q
A
D
F
G
N
R
R
A
R
E
L
R
--
I
D
D
H
V
----------
R
S
R
V
C
N
M
L
D
T
P
-----------------
F
-
D
K
-
G
A
V
T
A
S
W
-
N
-
N
E
----
S
TMY--
V
D
L
---
H
D
L
F
S
-
E
H
S
R
F
-----
L
K
V
G
G
-
R
Y
V
T
I
---
T
-------------
G
-----------------------------------------------------------------------------------------------------------
48
HHSearch
52.75
17%
-93
- C3 -
3MGG
-
?
A:
[34-141]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
P
G
A
---
K
V
L
E
A
---
G
--
C
G
I
-
G
A
Q
T
V
I
L
A
--
K
N
N
P
-
D
-
A
E
I
T
S
I
D
I
S
P
E
S
L
E
K
A
R
E
N
T
E
K
N
G
--
I
-
K
N
V
----------
K
F
L
Q
A
N
I
F
S
L
P
-----------------
F
-
E
D
-
S
S
F
D
H
I
F
-
V
-
C
F
----
V
LEHL-
Q
S
P
---
E
E
A
L
K
-
S
L
K
K
V
-----
L
K
P
G
G
-
T
I
T
V
I
---
E
-------------
G
-----------------------------------------------------------------------------------------------------------
44
HHSearch
51.69
11%
-98
- C3 -
3HM2
1
?
A:
[23-129]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
K
P
H
E
---
T
L
W
D
I
---
G
--
G
G
S
-
G
S
I
A
I
E
W
L
--
R
S
T
--
P
Q
T
T
A
V
C
F
E
I
S
E
E
R
R
E
R
I
L
S
N
A
I
N
L
G
--
V
S
D
R
I
----------
A
V
Q
Q
G
A
P
R
A
F
D
-----------------
D
-
V
P
-
D
N
P
D
V
I
F
-
I
-
G
G
----------
L
T
A
---
P
G
V
F
A
-
A
A
W
K
R
-----
L
P
V
G
G
-
R
L
V
A
N
---
A
-------------
V
T
----------------------------------------------------------------------------------------------------------
30
Fugue
50.90
13%
-48
- C3 -
1NW3
4
DOT1L_HUMAN
A:
[5-332]
L
E
L
R
L
K
S
PVGAE
P
A
V
Y
P
W
PLPVYDK
H
H
D
A
A
H
E
I
I
E
T
I
R
W
V
C
E
E
I
P
D
L
K
L
A
M
E
N
YVLIDY
D
T
K
S
F
E
--
S
M
Q
R
L
C
D
K
Y
N
R
-
A
I
D
S
-
I
H
Q
L
W
K
G
T
T
Q
P
M
K
L
N
T
R
P
S
T
G
-
L
L
R
H
I
L
Q
Q
V
Y
N
H
S
V
T
D
P
E
K
L
N
N
---
Y
-----
E
-----
P
F
S
P
E
V
Y
G
E
T
S
F
D
L
V
A
Q
M
I
D
E
I
K
M
T
D
D
D
---
L
F
V
D
L
---
G
--
S
G
V
G
Q
V
V
L
Q
V
A
A
--
A
T
N
--
C
-
K
H
H
Y
G
V
E
K
A
D
I
P
A
K
Y
A
E
T
M
D
R
E
F
R
--
K
W
M
K
W
Y
G
K
K
H
A
E
Y
T
L
E
R
G
D
F
L
S
E
E
W
R
-----------------
E
-
R
I
-
A
N
T
S
V
I
F
-
V
-
N
N
----
F
-----
A
F
G
---
P
E
V
D
H
-
Q
L
K
E
R
F
A
NMK
E
G
G
R
I
-
V
S
S
K
P
---
F
APLN
F
R
I
N
SRNLS
D
I
------------
G
T
I
M
R
V
V
E
L
S
P
---------
L
K
G
S
-
V
S
W
T
---
G
K
P
V
S
Y
Y
L
H
T
-
I
---
D
R
-
T
I
L
E
N
Y
F
S
--
S
L
K
N
P
-----------------------------
31
Fugue
50.88
11%
-30
- C3 -
3B89
1
?
A:
[3-251]
------------------------------------------
N
I
N
D
A
L
T
S
I
L
A
------
S
K
K
Y
R
A
--
L
C
P
D
T
V
R
R
I
L
T
E
E
W
G
R
-
H
K
S
P
K
Q
T
V
E
A
A
R
T
R
L
H
G
I
C
G
A
V
T
P
E
S
L
K
A
A
A
A
A
L
S
A
G
D
V
K
K
A
L
S
---
L
-----
H
-----
A
-
S
T
K
E
R
L
A
E
L
D
T
L
Y
D
F
I
F
S
A
---
E
T
P
R
---
R
V
L
D
I
---
A
--
C
G
L
N
P
L
A
L
Y
E
-----
R
G
--
I
-
A
S
V
W
G
C
D
I
H
Q
G
L
G
D
V
I
T
P
F
A
R
E
K
D
--
W
D
F
T
F
----------
A
L
Q
D
V
L
C
A
P
P
A
-----------------
E
-
A
G
-
D
L
A
L
I
F
K
L
L
-
P
L
----
L
-----
E
R
E
---
Q
A
G
S
A
M
A
L
L
Q
S
-----
L
N
T
P
R
M
A
V
S
F
P
-----------------
T
R
------------
S
E
A
N
Y
A
A
W
F
E
G
---------
G
L
P
A
-
E
F
E
I
---
E
D
K
K
T
I
G
T
E
L
-
I
---
Y
L
-
I
K
K
N
----------------------------------------
55
HHSearch
50.70
14%
-98
- C3 -
2NXC
-
PRMA_THET8
A:
[119-219]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
P
G
D
---
K
V
L
D
L
---
G
--
T
G
S
-
G
V
L
A
I
A
A
E
--
K
L
---
G
-
G
K
A
L
G
V
D
I
D
P
M
V
L
P
Q
A
E
A
N
A
K
R
N
G
--
V
--
R
P
----------
R
F
L
E
G
S
L
E
A
A
L
-----------------
P
-
F
G
-
P
F
D
L
L
V
A
-
N
-
L
Y
----
A
-----
E
L
H
---
A
A
L
A
P
-
R
Y
R
E
A
-----
L
V
P
G
G
-
R
A
L
L
T
---
G
-------------
I
-----------------------------------------------------------------------------------------------------------
43
HHSearch
50.58
15%
-83
- C3 -
1XXL
2
YCGJ_BACSU
A:
[18-124]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
C
R
A
E
H
---
R
V
L
D
I
---
G
--
A
G
A
-
G
H
T
A
L
A
F
S
--
P
Y
---
V
-
Q
E
C
I
G
V
D
A
T
K
E
M
V
E
V
A
S
S
F
A
Q
E
K
G
--
V
-
E
N
V
----------
R
F
Q
Q
G
T
A
E
S
L
P
-----------------
F
-
P
D
-
D
S
F
D
I
I
T
-
C
-
R
Y
AAHH
F
-----
S
D
V
---
R
K
A
V
R
-
E
V
A
R
V
-----
L
K
Q
D
G
-
R
F
L
L
V
---
D
-------------------------------------------------------------------------------------------------------------------------
50
HHSearch
45.99
7%
-78
- C3 -
2HNK
4
?
A:
[59-182]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
A
K
---
R
I
I
E
I
---
G
--
T
F
T
-
G
Y
S
S
L
C
F
A
--
S
A
L
PE
D
-
G
K
I
L
C
C
D
V
S
E
E
W
T
N
V
A
R
K
Y
W
K
E
N
G
--
L
E
N
K
I
----------
F
L
K
L
G
S
A
L
E
T
L
Q
V
L
I
D
SKSAPSWASD
F
A
F
G
P
S
-
S
I
D
L
F
F
L
-
D
-
A
D
----
K
-----
E
N
Y
---
P
N
Y
Y
P
-
L
I
L
K
L
-----
L
K
P
G
G
-
L
L
I
A
D
---
N
-------------
V
-----------------------------------------------------------------------------------------------------------
51
HHSearch
45.34
15%
-73
- C3 -
2KW5
-
?
A:
[27-132]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
P
Q
G
---
K
I
L
C
L
---
A
--
E
G
E
-
G
R
N
A
C
F
L
A
--
S
L
---
G
-
Y
E
V
T
A
V
D
Q
S
S
V
G
L
A
K
A
K
Q
L
A
Q
E
K
G
--
V
--
K
I
----------
T
T
V
Q
S
N
L
A
D
F
D
-----------------
I
-
V
A
-
D
A
W
E
G
I
V
-
S
-
I
F
----
C
HLPS-
S
L
R
---
Q
Q
L
Y
P
-
K
V
Y
Q
G
-----
L
K
P
G
G
-
V
F
I
L
E
---
G
-------------
F
-----------------------------------------------------------------------------------------------------------