@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA2369: (2016-04-03 )
MLEVKYDMRTGHYTPIPHEPHYLVISHADKLTATEKAKLRLLIIKQKLDISLAESVVSSPIASEHVIEQLTLFQHERRHLRPKISATFLAWLLIFLMFALPIGIAYQFSDWFQNQYVSAWIEYLTQTTLLNHDILQHILFGDYGVLSLGTYSLVWALPVVILISLSTAIIDQTGLKSWMIWAIEPSMLWIGLQGNDIVPLLEGFGCNAAAISQAAHQCHTCTKTQCMSLISFGSSCSYQIGATLSIFSVAGKSWLFMPYLILVLLGGILHNRIWLKKNDQQLSVPLPYDRQLHMPNIRQMLLQMWQNIQMFIVQALPIFITICLIVSILSLTPILNVLSQIFTPILSLLGISSELSPGILFSMIRKDGMLLFNLHQGALLQGMTATQLLLLVFFSSTFTACSVTMTMLLKHLGGQSALKLIGKQMVTSLSLVIGVGIIVKIVMLII
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------.........10........20........30..--..--....40........50........60.........----70........80........90........100......----.110....-...120.......130.......140.-......150.......160.......170.......-------180.......190.......200.......210-------------.........220.......---------230.......240.......250..-.....--.260....-...270.......280.......290.......300.....-..310...-....320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430..-----....-.440....-----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------
M
L
E
V
K
Y
DMRTGHYTPIPHEP
H
Y
L
V
I
SHADKLTA--TE--K
A
K
L
R
L
L
I
I
KQKL
D
I
S
L
A
E
S
V
V
SSP-I
A
S
E
H
V
I
E
Q
----
L
T
L
F
Q
H
E
R
R
H
LRP
K
I
S
A
T
F
L
A
W
L
L
I
F
L
M
F
ALPIG
I
A
Y
Q
F
----
S
D
W
F
Q
N
Q
Y
-
V
S
A
W
I
E
Y
L
T
Q
TTLL
N
H
D
I
L
Q
H
I
L
FGDY-
G
V
L
S
L
G
T
Y
S
L
V
W
A
L
P
V
V
I
L
I
S
L
S
T
A
I
I
D
Q
TGLK
S
W
M
-------
I
W
A
IEP
S
M
L
W
I
GLQGND
I
V
P
L
L
EGFGC
N
A
A
A
---------------
I
S
Q
A
A
H
Q
C
HTC
T
K
T
Q
C
M
S
L
---------
I
SFGSSC
S
Y
Q
IG
A
T
L
S
I
F
SVA-GK
S
-
W
L
F
M
P
--
Y
L
I
L
V
L
L
G
-
G
I
L
HN
R
I
W
L
KKNDQQLSVPLPYDRQLH
M
P
N
I
R
Q
M
L
L
Q
M
W
Q
N
-
I
Q
M
F
I
V
Q
A
-
L
P
I
F
I
T
I
C
L
I
V
S
I
L
S
L
T
P
I
L
N
V
L
S
Q
I
F
T
P
I
L
S
L
LGISSELS
P
G
I
L
F
S
M
I
RKD
G
M
L
L
F
NLHQ
G
A
L
L
Q
G
M
T
A
T
Q
L
L
L
L
V
F
FSST
F
T
A
C
S
V
T
M
T
M
L
L
K
HLG
G
Q
S
A
L
K
L
I
G
K
Q
M
V
T
S
L
S
L
V
I
G
-----
V
G
I
I
-
V
K
I
V
M
L
II-----------
31
Fugue
83.31
19%
-143
- C1 -
4ONQ
1
?
A:
[7-353]
-------------------------------------------------------------------------------------------------------
R
L
P
K
P
M
-
I
G
F
G
V
P
T
E
P
L
P
-----------------------------
A
M
V
R
R
T
L
P
S
Q
A
V
G
P
P
----------------
F
F
Y
Y
E
N
V
A
L
A
P
K
G
V
W
D
T
I
S
S
S
L
-------------------------------------------
Y
D
I
E
P
E
F
V
D
S
K
Y
-
F
C
A
A
A
R
K
R
G
Y
I
H
N
L
P
V
E
---------------
N
R
F
P
-------
L
F
P
L
A
P
R
T
I
H
E
A
L
------
P
L
S
K
K
W
W
P
S
W
D
P
---------------
R
----------
T
K
L
N
C
L
Q
T
---------
A
I
G
S
A
Q
L
T
N
R
I
R
K
A
V
E
D
F
D
---
G
E
P
-
P
M
R
V
Q
--
K
F
V
L
D
Q
C
R
-
K
W
--
N
L
V
W
V
G
R
N
---
K
V
A
P
L
E
-------
P
D
E
V
E
M
L
L
G
F
P
K
N
H
T
R
G
G
G
I
S
R
-
T
D
R
Y
K
S
L
G
N
S
F
Q
V
D
T
V
A
Y
H
L
S
V
L
K
D
L
F
P
G
G
I
N
V
L
S
L
F
S
G
I
G
-
G
G
E
V
A
L
Y
R
----
L
G
I
P
L
N
T
V
V
S
V
E
K
S
E
V
N
R
D
I
V
R
S
W
W
E
Q
T
N
Q
R
G
N
L
I
H
F
N
D
V
Q
Q
L
N
G
D
R
L
E
Q
L
I
E
S
F
--
G
G
F
D
L
V
I
G
G
SPS
L
F
S
S
Y
-
V
R
I
L
D
L
V
K
S
I
M
S-------
28
Fugue
54.95
13%
-83
- C3 -
4YCZ
-
?
B:
[66-928]
S
E
Y
R
Y
A
A
L
A
K
D
A
Y
QQ
M
G
T
A
PVTE
P
P
Q
V
I
L
G
T
E
D
L
L
S
R
L
Y
D
EKM
D
D
T
L
A
T
A
A
A
Q
L
A
A
L
W
R
E
H
V
D
ET
P
F
E
K
A
N
Y
L
A
N
L
A
L
Q
I
H
HP
L
P
Q
T
L
F
R
W
LNEYHMYGS
Q
V
D
D
I
L
R
H
R
P
S
P
A
C
H
S
L
F
W
Q
A
V
F
I
A
L
K
V
G
D
A
A
R
L
--
L
D
--
Q
A
G
W
G
H
V
Y
A
Y
V
N
V
Q
R
A
V
D
E
T
I
A
V
L
E
S
C
P
T
L
F
R
V
R
A
----
R
G
L
L
E
H
L
R
R
F
A
E
G
-----
W
E
I
Y
E
N
L
N
I
V
F
D
I
V
L
G
Q
Q
G
A
I
L
E
A
A
Q
D
W
L
E
A
T
V
G
L
A
N
S
E
S
Y
L
D
R
L
A
R
A
F
H
T
A
V
E
S
D
F
V
E
I
G
M
A
C
V
F
E
D
N
I
K
G
V
I
G
L
L
R
G
W
S
L
P
I
A
A
A
V
A
E
I
A
S
L
G
K
W
L
EVDG
I
K
D
S
T
L
V
Q
Y
A
Q
A
L
A
D
Y
E
G
L
S
S
V
Q
D
R
D
G
W
E
L
S
I
S
V
L
G
RMPER
S
E
E
M
V
R
D
L
V
E
H
L
V
Q
Q
L
H
V
D
S
N
A
T
V
D
R
L
W
F
L
L
N
ELGM
I
E
F
A
E
D
T
T
E
T
Y
G
D
I
L
A
R
D
S
H
R
Y
G
E
A
M
W
Y
Y
A
L
AH
R
P
N
K
V
R
E
V
M
N
L
L
T
S
Y
S
L
I
Q
P
P
A
N
D
L
D
---
D
Y
L
Y
K
L
L
N
D
R
K
N
T
L
E
Q
C
A
S
Q
D
M
E
A
A
E
L
L
G
K
M
L
S
G
Y
A
S
L
R
Q
F
Y
D
I
R
P
H
A
T
P
L
S
R
R
K
Q
A
A
T
A
L
I
S
V
--
I
A
S
S
D
D
E
D
F
L
L
A
L
L
G
E
A
-
L
V
F
V
S
D
P
T
L
D
Q
I
D
V
L
L
K
A
I
E
D
L
Q
A
V
G
S
R
V
Y
N
A
C
D
E
F
L
Q
L
V
L
A
S
A
P
G
--
G
S
S
L
V
A
S
Q
L
Q
R
S
L
S
G
T
-
G
-----
G
E
D
I
M
R
R
L
R
L
G
L
A
K
D
L
A
G
LWLAEA
5
HHSearch
35.47
12%
59
- C4 -
3K53
-
?
A:
[109-151]
----------------------------------------------------------------------------------------------------------------------
V
K
N
I
I
L
V
L
N
K
F
D
L
L
K
K
--
K
G
A-
K
I
D
I
K
K
M
R
K
E
L
G
V
P
V
I
P
T
N
A
K
K
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
33.87
7%
77
- C4 -
2WJI
1
FEOB_METJA
A:
[108-151]
----------------------------------------------------------------------------------------------------------------------
G
A
N
L
L
L
A
L
N
K
M
D
L
A
K
S
--
L
G
I-
E
I
D
V
D
K
L
E
K
I
L
G
V
K
V
V
P
L
S
A
A
K
K
M
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
32.93
16%
104
- C4 -
3CBQ
2
REM2_HUMAN
A:
[129-173]
---------------------------------------------------------------------------------------------------------------------
H
D
L
P
V
I
L
V
G
N
K
S
D
L
A
R
S
--
R
E
VS
L
E
E
G
R
H
L
A
G
T
L
S
C
K
H
I
E
T
S
A
A
L
H
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
32.36
14%
89
- C4 -
2CE2
1
RASH_HUMAN
X:
[107-150]
---------------------------------------------------------------------------------------------------------------------
D
D
V
P
M
V
L
V
G
N
K
S
D
L
A
A
R
--
T
V
E-
S
R
Q
A
Q
D
L
A
R
S
Y
G
I
P
Y
I
E
T
S
A
K
T
R
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
32.01
16%
69
- C4 -
3A1S
2
?
A:
[110-153]
----------------------------------------------------------------------------------------------------------------------
E
K
K
V
I
L
A
M
T
A
I
D
E
A
K
K
--
T
G
M
-
K
I
D
R
Y
E
L
Q
K
H
L
G
I
P
V
V
F
T
S
S
V
T
G
E
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
31.37
14%
80
- C4 -
2EW1
1
RAB30_HUMAN
A:
[130-174]
---------------------------------------------------------------------------------------------------------------------
N
K
V
I
T
V
L
V
G
N
K
I
D
L
A
E
R
--
R
E
VS
Q
Q
R
A
E
E
F
S
E
A
Q
D
M
Y
Y
L
E
T
S
A
K
E
S
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
31.28
12%
84
- C4 -
1Z06
1
RB33B_MOUSE
A:
[126-170]
---------------------------------------------------------------------------------------------------------------------
N
D
I
P
R
I
L
V
G
N
K
C
D
L
R
S
A
--
I
Q
VP
T
D
L
A
Q
K
F
A
D
T
H
S
M
P
L
F
E
T
S
A
K
N
P
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
30.67
7%
77
- C4 -
2WJG
1
FEOB_METJA
A:
[112-155]
----------------------------------------------------------------------------------------------------------------------
G
A
N
L
L
L
A
L
N
K
M
D
L
A
K
S
--
L
G
I-
E
I
D
V
D
K
L
E
K
I
L
G
V
K
V
V
P
L
S
A
A
K
K
M
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
29.99
11%
98
* C4 *
3CLV
1
?
A:
[146-190]
---------------------------------------------------------------------------------------------------------------------
S
N
Y
I
I
I
L
V
A
N
K
I
D
K
N
-
F
--
Q
V
D-
I
L
E
V
Q
K
Y
A
Q
D
N
N
L
L
F
I
Q
T
S
A
K
T
G
T
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
29.99
16%
99
- C4 -
1OIX
1
RB11A_HUMAN
A:
[133-177]
---------------------------------------------------------------------------------------------------------------------
S
N
I
V
I
M
L
V
G
N
K
S
D
L
R
H
L
--
R
A
VP
T
D
E
A
R
A
F
A
E
K
N
G
L
S
F
I
E
T
S
A
L
D
S
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
29.69
19%
83
- C4 -
2OIL
1
RAB25_HUMAN
A:
[129-173]
---------------------------------------------------------------------------------------------------------------------
A
T
I
V
V
M
L
V
G
N
K
S
D
L
S
Q
A
--
R
E
VP
T
E
E
A
R
M
F
A
E
N
N
G
L
L
F
L
E
T
S
A
L
D
S
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
29.37
12%
70
- C4 -
3B1V
1
?
A:
[106-149]
---------------------------------------------------------------------------------------------------------------------
T
G
I
P
V
T
I
A
L
N
M
I
D
V
L
D
G
--
Q
G
K-
K
I
N
V
D
K
L
S
Y
H
L
G
V
P
V
V
A
T
S
A
L
K
Q
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
28.38
16%
88
- C4 -
2G3Y
1
GEM_HUMAN
A:
[144-188]
---------------------------------------------------------------------------------------------------------------------
E
D
I
P
I
I
L
V
G
N
K
S
D
L
V
R
C
--
R
E
VS
V
S
E
G
R
A
C
A
V
V
F
D
C
K
F
I
E
T
S
A
A
V
Q
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
27.54
10%
79
- C4 -
3I8S
-
FEOB_ECOLI
A:
[112-154]
----------------------------------------------------------------------------------------------------------------------
G
I
P
C
I
V
A
L
N
M
L
D
I
A
E
K
--
Q
N
I-
R
I
E
I
D
A
L
S
A
R
L
G
C
P
V
I
P
L
V
S
T
R
G
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
27.45
23%
92
- C3 -
2L8T
-
?
A:
[2-72]
-----------------------------------------------------------------------------------------------------------------------
E
T
K
Y
E
L
N
N
T
K
K
V
A
N
A
F
G
L
N
--
E
E
D
T
N
L
L
I
N
A
V
D
L
D
I
K
N
N
M
Q
E
I
S
S
E
-
L
Q
Q
S
E
Q
S
K
Q
KQYG
T
T
L
Q
N
L
A
K
Q
N
R
I
I
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
HHSearch
26.64
7%
80
- C4 -
3IBY
-
FEOB_LEGPN
A:
[109-157]
---------------------------------------------------------------------------------------------------------------------
L
G
K
P
V
V
V
A
L
N
M
M
D
I
A
E
H
--
R
G
I-
S
I
D
T
E
K
L
E
S
L
L
G
C
S
V
I
P
I
Q
A
H
K
N
I
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
26.24
12%
94
- C4 -
2ATV
1
RERG_HUMAN
A:
[131-175]
---------------------------------------------------------------------------------------------------------------------
K
N
V
T
L
I
L
V
G
N
K
A
D
L
D
H
S
--
R
Q
VS
T
E
E
G
E
K
L
A
T
E
L
A
C
A
F
Y
E
C
S
A
C
T
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
26.03
14%
91
- C4 -
3C5C
2
RASLC_HUMAN
A:
[125-169]
--------------------------------------------------------------------------------------------------------------------
Q
R
S
I
P
A
L
L
L
G
N
K
L
D
M
A
Q
Y
--
R
Q
VT
K
A
E
G
V
A
L
A
G
R
F
G
C
L
F
F
E
V
S
A
C
L
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------