@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0014: (2015-12-11 )
MIILSASVKNLREISVKEKFLWLNAKSYLISVFAPFILLPWIDLLSAFLLYLGFLALFSVLEFFDEDIADIIIAKSKIKTKTKCYRA
Atome Classification :
(15 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....----.....10...---------....--.20........30...------.....------40........50....-------...-----.60........70.---.......80......---------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
I
L----S
A
S
V
K
N
L
R
E
I
---------
S
VK
E
--
K
F
L
W
LN
A
K
S
Y
L
I
S
V
F
A
------
P
F
I
L
L
------
P
W
I
D
L
L
S
A
F
L
L
Y
L
G
F
L
-------
A
L
F
-----
S
V
L
E
F
F
D
E
D
I
A
D
I
I
---IAKSKIKTKTKCYRA---------------------------------------
12
Fugue
74.99
22%
-80
- C5 -
1JB0
13
PSAA_THEEB
A:
[13-755]
---R
V
V
V
D
N
DPVPTSF
E
K
W
A
K
PGHFDRTLARGPQTT
T
W
I
W
N
L
H
A
L
A
HDFDTHTSD
L
E
D
I
S
R
K
I
F
S
A
H
F
G
H
L
A
V
V
F
I
W
L
S
G
M
Y
F
H
G
A
KFSN
Y
E
A
W
L
A
D
P
TG
I
K
P
S
A
Q
VVWPIVGQGILNGDVGGGFHGIQITSG
L
F
Q
L
W
R
A
S
GITN
E
F
Q
L
Y
C
T
A
I
G
G
L
V
M
A
G
L
M
L
F
A
G
W
F
H
Y
HK
R
A
P
K
L
E
W
F
Q
N
V
E
S
M
L
N
H
H
L
AG
L
L
G
L
G
S
L
A
W
A
G
H
Q
I
H
V
S
L
P
I
N
K
L
L
D
A
GVAAKDIPL
P
H
E
F
I
L
N
P
S
L
M
A
E
L
YPKVDWGFFSPFFTFNWAAYSDFLTFNGGLNPVTGGLW
L
S
D
T
A
H
H
H
L
A
I
A
V
L
F
I
I
A
G
H
MYRTNWGIGHS
L
K
E
I
L
E
A
HKGPFTGAGHKG
L
Y
E
V
L
T
T
S
W
H
A
Q
L
A
I
N
L
A
M
M
G
S
L
S
I
I
V
A
Q
H
M
Y
A
M
PPYPYLATD
Y
P
T
Q
L
S
L
F
T
H
H
M
W
I
G
G
F
L
V
V
G
G
A
A
H
G
A
I
F
M
V
RDYDPAMNQNN
V
L
D
R
V
L
R
H
R
D
A
I
I
S
H
L
N
W
V
C
I
F
L
G
F
H
S
F
G
L
Y
V
H
N
D
T
M
R
A
F
GRPQDMFSDTGIQLQP
V
F
A
Q
W
V
Q
N
L
H
T
L
APGGTAPNAAATASVAFG
G
D
V
V
A
V
GGKVAM
M
P
I
V
L
G
T
A
D
F
M
V
H
H
I
H
A
F
T
I
H
V
T
V
L
I
L
L
K
G
V
L
F
A
RSSRLIPDKANLGFRFPCDGPGRGGTCQVS
G
W
D
H
V
F
L
G
L
F
W
M
Y
N
C
I
S
V
V
I
F
H
F
S
W
K
M
Q
S
D
V
W
G
T
V
A
PDG
T
V
S
H
IT
G
G
N
F
----
A
Q
S
A
I
T
I
N
-----------
G
W
L
R
--
D
F
L
W
A
Q
A
S
Q
V
I
G
S
Y
--GS----
A
L
S
A
Y
------
G
L
L
F
L
G
A
H
F
I
W
A
F
S
L
M
-------
F
L
F
-----
S
G
R
G
Y
W
Q
E
L
I
E
S
I
V
---
W
A
H
N
K
L
----
K
V
A
P
A
I
Q
P
R
A
L
S
I
I
Q
G
R
A
V
G
V
A
H
Y
L
L
G
G
I
A
T
T
W
A
F
F
L
A
R
I
ISVG
15
Fugue
71.46
19%
-69
- C5 -
1JB0
13
PSAA_THEEB
A:
[13-755]
R
V
V
V
D
N
DPVPTSF
E
K
W
A
K
PGHFDRTLARGPQTT
T
W
I
W
N
L
H
A
L
A
HDFDTHTSD
L
E
D
I
S
R
K
I
F
S
A
H
F
G
H
L
A
V
V
F
I
W
L
S
G
M
Y
F
H
G
A
KFSN
Y
E
A
W
L
A
D
P
TG
I
K
P
S
A
Q
VVWPIVGQGILNGDVGGGFHGIQITSG
L
F
Q
L
W
R
A
S
GITN
E
F
Q
L
Y
C
T
A
I
G
G
L
V
M
A
G
L
M
L
F
A
G
W
F
H
Y
HK
R
A
P
K
L
E
W
F
Q
N
V
E
S
M
L
N
H
H
L
AG
L
L
G
L
G
S
L
A
W
A
G
H
Q
I
H
V
S
L
P
I
N
K
L
L
D
A
GVAAKDIPL
P
H
E
F
I
L
N
P
S
L
M
A
E
L
YPKVDWGFFSPFFTFNWAAYSDFLTFNGGLNPVTGGLW
L
S
D
T
A
H
H
H
L
A
I
A
V
L
F
I
I
A
G
H
MYRTNWGIGHS
L
K
E
I
L
E
A
HKGPFTGAGHKG
L
Y
E
V
L
T
T
S
W
H
A
Q
L
A
I
N
L
A
M
M
G
S
L
S
I
I
V
A
Q
H
M
Y
A
M
PPYPYLATD
Y
P
T
Q
L
S
L
F
T
H
H
M
W
I
G
G
F
L
V
V
G
G
A
A
H
G
A
I
F
M
V
RDYDPAMNQNN
V
L
D
R
V
L
R
H
R
D
A
I
I
S
H
L
N
W
V
C
I
F
L
G
F
H
S
F
G
L
Y
V
H
N
D
T
M
R
A
F
GRPQDMFSDTGIQLQP
V
F
A
Q
W
V
Q
N
L
H
T
L
APGGTAPNAAATASVAFG
G
D
V
V
A
V
GGKVAM
M
P
I
V
L
G
T
A
D
F
M
V
H
H
I
H
A
F
T
I
H
V
T
V
L
I
L
L
K
G
V
L
F
A
RSSRLIPDKANLGFRFPCDGPGRGGTCQVS
G
W
D
H
V
F
L
G
L
F
W
M
Y
N
C
I
S
V
V
I
F
H
F
S
W
K
M
Q
S
D
V
W
G
T
V
A
PDG
T
V
S
H
ITGGN
F
A
Q
S
----
A
I
T
I
N
G
W
L
R
----------------
D
F
L
W
A
Q
A
S
Q
V
I
G
S
Y
G
S
------
A
L
S
A
Y
------
G
L
L
F
L
G
A
H
F
I
W
A
F
S
L
M
-------
F
L
F
-----
S
G
R
G
Y
W
Q
E
L
I
E
S
I
V
---
W
A
H
N
K
L
K
V
A
P
A
I
Q
P
R
A
L
S
I
I
Q
G
R
A
V
G
V
A
H
Y
L
L
G
G
I
A
T
T
W
A
F
F
L
A
R
I
ISVG----
17
Fugue
69.34
22%
-136
- C3 -
4TSD
2
?
A:
[2-180]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AIFGELSSLGHLFKKTQEL
E
I
L
H
E
Y
L
K
E
V
M
QKGS
K
A
N
Q
R
V
L
N
LATN
T
E
F
Q
V
P
LGHG
I
F
S
I
E
Q
S
Y
C
L
EHAKESE
K
G
F
F
E
S
H
K
K
Y
V
D
F
Q
L
I
V
K
G
V
E
G
A
K
A
V
G
I
N
Q
A
---------
V
I
K
N
--
P
Y
D
----
E
K
R
D
L
I
V
Y
E
------
P
------------
V
S
E
A
S
F
L
R
L
H
A
G
M
L
-------
A
I
F
F
EN
D
A
H
A
L
R
F
Y
G
E
S
F
E
K
Y
R
E
E
P
I
F
K
A
V
V
K
A
P
K
G
L
I
K
L
K
LAA-----------------------------------
20
Fugue
60.03
10%
-134
- C5 -
4JOI
-
TEN1L_HUMAN
C:
[1-118]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
P
K
----
P
G
T
Y
Y
L
P
W
E
V
S
A
GQVPDG
S
T
L
R
T
F
G
R
L
C
L
Y
D
M
I
Q
S
R
V
T
L
M
A
Q
HGS
D
Q
H
Q
V
L
V
C
TKLVE
P
F
H
A
Q
V
G
S
L
Y
I
V
L
G
E
L
Q
H
Q
QD
R
G
S
V
V
-----
K
A
R
V
L
T
C
V
E
G
M
N
L
P
---
L
L
E
Q
A
I
R
E
Q
R
L
Y
K
Q
E
R--------------------------------------
18
Fugue
59.30
15%
-7
* C5 *
1F02
-
?
T:
[271-336]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
Q
----
A
A
N
A
A
E
S
A
T
K
---------
D
Q
L
T
--
Q
E
A
F
K
N
P
E
N
Q
K
V
N
I
D
A
------
N
G
N
A
I
------
P
S
G
E
L
K
--------------------------------
D
D
I
V
E
Q
I
---
A
Q
Q
A
K
E
A
G
E
V
A
R
Q
Q
A
---------------------------------------
2
HHSearch
50.20
12%
-137
- C- -
3IXZ
-
ATP4B_PIG
B:
[33-69]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
S
R
W
V
W
------------
I
S
L
------
Y
Y
V
A
-
F
Y
V
V
M
S
G
I
F
A
L
-------
C
I
Y
-----
V
L
M
R
T
I
D
P
Y
T
P
D
Y
Q
---
D
Q
L
K
--------------------------------------------------
3
HHSearch
42.69
21%
-158
- C5 -
3WGU
4
AT1B1_PIG
B:
[23-64]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
L
G
R
T
G
G
S
W
F
------------
K
I
L
L
------
F
Y
V
I
-
F
Y
G
C
L
A
G
I
F
I
G
-------
T
I
Q
-----
V
M
L
L
T
I
S
E
F
K
P
T
Y
Q
---
D
R
V
A
P
P
G
L
T
Q
I
P
Q
S
Q
---------------------------------------
1
HHSearch
40.34
16%
-149
- C5 -
2ZXE
1
?
B:
[28-65]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
G
S
S
W
F
------------
K
I
F
L
------
F
Y
L
I
-
F
Y
G
C
L
A
G
I
F
I
G
-------
T
I
Q
-----
V
L
L
L
T
L
S
D
F
E
P
K
Y
Q
---
D
R
V
A
P
P
G
L
S
H
A
P
Y
A
I
---------------------------------------
11
Fugue
33.87
19%
88
- C5 -
2LR1
-
B:
[1-21]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
E
A
L
K
K
A
---------
L
R
R
H
--
R
F
L
W
Q
R
R
Q
R
A
-----------------------------------------------------------------------------------------------------------------------------
8
HHSearch
31.13
50%
138
- C2 -
1R4G
-
PHOSP_SENDH
A:
[555-564]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
M
E
L
V
E
E
D
I
E
------------------------------------------------------------
5
HHSearch
30.77
18%
90
- C5 -
2JVD
-
YNZC_BACSU
A:
[8-24]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
I
N
E
L
---------
A
A
K
A
--
K
A
G
V
I
T
E
E
E
K
A
E
Q
Q
K
L
------
R
Q
E
Y
L
------
K
G
F
R
S
S
M
K
L
E
--------------------------------------------------------------------------------------------
4
HHSearch
30.05
44%
216
- C1 -
2LF0
-
?
A:
[73-81]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
A
I
---------
T
K
K
E
--
Q
A
D
M
G
K
L
K
K
S
V
R
G
L
V
V
------
V
H
P
M
T
------
A
L
G
R
E
M
G
L
E
E
M
T
G
F
S
K
-------
T
T
F
----------------------------------------------------------------------------
13
Fugue
28.41
28%
-8
- C4 -
4J2L
1
CIC_HUMAN
C:
[1-25]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
V
W
T
N
V
E
P
R
S
V
A
V
F
P
------
W
H
S
L
V
------
P
F
L
A
--------------------------------------------------------------------------------------------------
10
HHSearch
23.98
19%
36
- C6 -
2PH0
-
?
A:
[120-135]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-----
A
S
V
V
F
F
N
A
N
G
A
A
M
F
---
K
I
F
L
G
R
D
S
H
R
Q
L
L
S
A
---------------------------------------
9
HHSearch
14.45
21%
117
* C6 *
3FM2
-
?
A:
[83-96]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-----
Y
A
I
R
F
L
D
E
K
Q
E
S
A
L
---
S
L
F
L
Q
W
G
K
P
G
E
Y
E
P
G
---------------------------------------