@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0062: (2015-12-12 )
MNTYAQESKLRLKTKIGADGRCVIEDNFFTPPFKLMAPFYPKDDLAEIMLLAVSPGLMKGDAQDMQLNIGPNCKLRITSQSFEKIHNTEDGFASRDMHIVVGENAFLDFAPFPLIPFENAHFKGNTTISLRSSSQLLYSEIIVAGRVARNELFKFNRLHTKISILQDEKPIYYDNTILDPKTTNMNNMCMFDGYTHYLNLVLVNCPIELSGARELIEESEGVDGAVSKIASSHLCLKALAKGSEPLLHLREKIARLVTQTTTQKV
Atome Classification :
(19 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10-.........20........30...---.....40..-.......50........60.....-----..------.70.......----.80........90------------......---...100.......110---.....-....120.......130.......140.....-----..150.......160....-...170........180-.......190.----------......200.-------------......210-.........220.--......230.......-240........250.......260...---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTYAQES
K
L
--
R
L
K
T
KIGAD
G
R
C
V
I
EDNFFTP
P
F
K
---
L
MAPFY-
P
K
-
D
D
L
A
E
I
M
L
L
AVSPGLMKGDAQ
D
M
Q
-----
L
N------IGPN
C
K
L
R
I
T
----
S
Q
S
F
E
K
I
HNTED-------------GFASR
D
---
M
H
I
V
VGEN
A
F
LDFA-----PFPLI-PFENAHFKGN
T
T
I
S
LRSS
S
Q
L
L
Y
S
E
I
I
V
A
G
R
V
-----
A
R
N
E
L
F
K
F
NRL
H
T
K
I
S
I
LQ-DEK
P
-
I
YYDNTILDPKT-TNMN
N
M
C
M
FDG----------Y
T
H
Y
L
N
L
V
L
V
-------------NCPIELS---
G
A
R
E
L
I
E
ESEGV
D
--
G
A
V
S
K
I
A
S
S
H
L
C
L
K
A
L
-AK-GS
E
P
L
L
H
L
R
E
K
I
A
R
L
V
T
Q
TTTQKV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
99.54
96%
-117
- C4 -
3SF5
5
UREH_HELPY
B:
[5-265]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
E
S
K
L
--
R
L
K
T
K
I
G
A
D
G
R
C
V
I
E
D
N
F
F
T
P
P
F
K
---
L
M
A
P
F
Y
-
P
K
-
D
D
L
A
E
I
M
L
L
A
V
S
P
G
M
M
R
G
D
A
Q
D
V
Q
-----
L
N
------
I
G
P
N
C
K
L
R
I
T
----
S
Q
S
F
E
K
I
H
N
T
E
D
-------------
G
F
A
S
R
D
---
M
H
I
V
V
G
E
N
A
F
L
D
F
A
-----
P
F
P
L
I
-
P
F
E
N
A
H
F
K
G
N
T
T
I
S
L
R
S
S
S
Q
L
L
Y
S
E
I
I
V
A
G
R
V
-----
A
R
N
E
L
F
K
F
N
R
L
H
T
K
I
S
I
L
Q
-
D
E
K
P
-
I
Y
Y
D
N
T
I
L
D
P
K
T
-
T
D
L
N
N
M
C
M
F
D
G
----------
Y
T
H
Y
L
N
L
V
L
V
-------------
N
C
P
I
E
L
S
---
G
V
R
E
C
I
E
E
S
E
G
V
D
--
G
A
V
S
E
T
A
S
S
H
L
C
V
K
A
L
-
A
K
-
G
S
E
P
L
L
H
L
R
E
K
I
A
R
L
V
T
Q
T
T
T
Q
K
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
99.54
96%
-117
- C4 -
3SF5
5
UREH_HELPY
B:
[5-265]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
E
S
K
L
--
R
L
K
T
K
I
G
A
D
G
R
C
V
I
E
D
N
F
F
T
P
P
F
K
---
L
M
A
P
F
Y
-
P
K
-
D
D
L
A
E
I
M
L
L
A
V
S
P
G
M
M
R
G
D
A
Q
D
V
Q
-----
L
N
------
I
G
P
N
C
K
L
R
I
T
----
S
Q
S
F
E
K
I
H
N
T
E
D
-------------
G
F
A
S
R
D
---
M
H
I
V
V
G
E
N
A
F
L
D
F
A
-----
P
F
P
L
I
-
P
F
E
N
A
H
F
K
G
N
T
T
I
S
L
R
S
S
S
Q
L
L
Y
S
E
I
I
V
A
G
R
V
-----
A
R
N
E
L
F
K
F
N
R
L
H
T
K
I
S
I
L
Q
-
D
E
K
P
-
I
Y
Y
D
N
T
I
L
D
P
K
T
-
T
D
L
N
N
M
C
M
F
D
G
----------
Y
T
H
Y
L
N
L
V
L
V
-------------
N
C
P
I
E
L
S
---
G
V
R
E
C
I
E
E
S
E
G
V
D
--
G
A
V
S
E
T
A
S
S
H
L
C
V
K
A
L
-
A
K
-
G
S
E
P
L
L
H
L
R
E
K
I
A
R
L
V
T
Q
T
T
T
Q
K
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_CBE
99.04
96%
-119
- C4 -
3SF5
3
UREH_HELPY
D:
[2-261]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
T
Y
A
Q
E
S
K
L
--
R
L
K
T
K
I
G
A
D
G
R
C
V
I
E
D
N
F
F
T
P
P
F
K
---
L
M
A
P
F
Y
-
P
K
-
D
D
L
A
E
I
M
L
L
A
V
S
P
G
M
M
R
G
D
A
Q
D
V
Q
-----
L
N
------
I
G
P
N
C
K
L
R
I
T
----
S
Q
S
F
E
K
I
H
N
T
E
D
-------------
G
F
A
S
R
D
---
M
H
I
V
V
G
E
N
A
F
L
D
F
A
-----
P
F
P
L
I
-
P
F
E
N
A
H
F
K
G
N
T
T
I
S
L
R
S
S
S
Q
L
L
Y
S
E
I
I
V
A
G
R
V
-----
A
R
N
E
L
F
K
F
N
R
L
H
T
K
I
S
I
L
Q
-
D
E
K
P
-
I
Y
Y
D
N
T
I
L
D
P
K
T
-
T
D
L
N
N
M
C
M
F
D
G
----------
Y
T
H
Y
L
N
L
V
L
V
-------------
N
C
P
I
E
L
S
---
G
V
R
E
C
I
E
E
S
E
G
V
D
--
G
A
V
S
E
T
A
S
S
H
L
C
V
K
A
L
-
A
K
-
G
S
E
P
L
L
H
L
R
E
K
I
A
R
L
V
T
Q
T
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
98.30
96%
-117
- C4 -
4HI0
-
UREH_HELPY
B:
[6-260]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
S
K
L
--
R
L
K
T
K
I
G
A
D
G
R
C
V
I
E
D
N
F
F
T
P
P
F
K
---
L
M
A
P
F
Y
-
P
K
-
D
D
L
A
E
I
M
L
L
A
V
S
P
G
M
M
R
G
D
A
Q
D
V
Q
-----
L
N
------
I
G
P
N
C
K
L
R
I
T
----
S
Q
S
F
E
K
I
H
N
T
E
D
-------------
G
F
A
S
R
D
---
M
H
I
V
V
G
E
N
A
F
L
D
F
A
-----
P
F
P
L
I
-
P
F
E
N
A
H
F
K
G
N
T
T
I
S
L
R
S
S
S
Q
L
L
Y
S
E
I
I
V
A
G
R
V
-----
A
R
N
E
L
F
K
F
N
R
L
H
T
K
I
S
I
L
Q
-
D
E
K
P
-
I
Y
Y
D
N
T
I
L
D
P
K
T
-
T
D
L
N
N
M
C
M
F
D
G
----------
Y
T
H
Y
L
N
L
V
L
V
-------------
N
C
P
I
E
L
S
---
G
V
R
E
C
I
E
E
S
E
G
V
D
--
G
A
V
S
E
T
A
S
S
H
L
C
V
K
A
L
-
A
K
-
G
S
E
P
L
L
H
L
R
E
K
I
A
R
L
V
T
Q
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
48.09
16%
-75
- C3 -
4I43
-
PRP8_YEAST
B:
[882-2396]
G
S
G
V
M
V
E
W
L
E
S
R
SFSPIPFPPLTYKN
D
T
K
I
L
V
L
A
L
E
D
L
K
DVYASKVRLN
A
S
E
R
E
E
L
A
L
I
E
E
A
Y
D
N
P
H
D
T
L
N
R
I
K
K
Y
L
L
TQRVF
K
P
V
D
I
TP
V
Y
S
V
D
P
L
E
K
I
T
D
A
Y
L
D
Q
Y
L
W
Y
E
A
D
Q
R
KLFPNWIKPSDSEI
P
P
L
L
V
Y
K
W
T
Q
G
I
N
N
LSEIWDVSRG
Q
S
A
V
L
L
E
T
T
LGEMAEKID
F
T
L
L
N
R
L
L
R
L
I
VD
P
N
I
A
D
Y
I
T
A
K
N
N
V
V
I
N
F
KD
M
S
H
V
NKYGLIRGLKF
A
S
F
I
F
Q
Y
Y
G
L
V
I
D
L
L
L
L
G
Q
E
R
A
T
D
L
A
GPAN
N
P
N
E
FMQFKS
K
E
V
E
K
AHPIR
L
Y
T
R
YLD
R
I
Y
M
L
F
H
F
E
E
D
E
G
E
E
L
T
D
E
Y
L
A
E
N
PDPNFENSIGYNNRKCWPKDSRMRLI
R
Q
D
V
N
L
G
R
A
V
F
W
E
I
Q
S
R
V
PTSL
T
S
I
K
WEN
A
F
V
S
V
Y
S
KNNP
N
L
L
F
S
M
CG
F
E
V
R
I
L
P
RQRMEENDEG
V
W
D
L
V
DERTKQRT
A
K
A
Y
L
K
V
S
E
E
E
I
K
K
F
D
S
R
I
R
G
I
L
M
ASTT
F
T
K
V
A
A
K
W
N
T
S
L
I
S
L
F
T
Y
FR
E
A
I
V
A
T
E
P
L
L
D
I
L
V
K
G
E
T
R
I
Q
N
R
V
K
L
G
L
NSKMPTRFPPAVFYTPKELGGLGMISASHILIPASDL
S
W
S
K
Q
T
DT
G
I
T
H
F
R
AGMTHEDEKLIPTIFRYITT
W
E
N
E
F
L
D
S
Q
R
V
W
A
E
Y
A
T
K
R
Q
E
A
I
Q
Q
NRRLAFEELEGSWDRGIPR
I
S
T
L
F
QRDRHTLAYDRG
H
R
I
R
R
E
F
KQYSLERNSPFWWTNSHHDGKLWNL
N
A
Y
R
T
D
V
I
Q
A
L
GG
I
E
T
I
L
E
H
T
LFKGTGFNSWEGLFWLSQIP
N
R
R
F
T
L
W
W
SPTINRANVYVG
F
L
V
Q
L
D
LTGIFLHGKIPT
L
K
I
S
L
I
Q
I
F
RAH
L
W
Q
K
I
H
E
S
I
V
F
D
I
C
Q
I
L
D
G
E
L
DVLQIESVTK
E
T
V
H
PRKSYKMN
S
S
A
A
D
I
T
M
E
S
VHEWEVSKPSLLHETNDSFKGLITN
K
M
W
F
D
V
Q
L
R
Y
G
D
YDSHD
I
S
R
Y
V
R
A
K
F
L
D
Y
T
T
DNVSMYPSP
T
G
V
M
I
G
I
DLAYN
M
Y
D
A
Y
G
NWFNG
L
K
P
L
I
Q
N
S
M
R
T
I
M
K
A
N
P
A
L
Y
V
L
R
E
R
I
R
K
G
L
QIYQEPFLNSSNYAELFNND
I
K
L
F
V
D
D
T
N
V
Y
--------
R
V
T
V
H
K
T
F
E
G
------
N
V
A
T
K
A
I
N
---
G
C
I
F
T
L
N
P
K
-
T
G
--
H
L
F
L
K
I
I
H
T
S
V
W
A
G
-----
Q
-----
K
R
------
L
S
Q
L
A
K
W
K
T
A
----
E
E
V
S
A
L
V
R
S
L
P
---------------
K
E
E
Q
P
---
K
Q
I
I
V
T
R
K
A
M
L
D
P
L
-----
E
V
H
M
L
-
D
F
P
N
--------
I
A
I
R
P
T
E
L
R
L
P
F
S
A
A
M
S
I
D
K
-----
L
S
D
V
V
M
K
-------------
A
T
E
P
-
Q
M
V
L
F
N
I
Y
D
D
W
L
-
D
R
I
S
S
Y
T
A
F
S
R
----------
L
T
L
L
L
R
A
L
K
T
-------------
N
----
E
E
---
S
A
K
M
I
L
L
S
D
P
--------
T
I
T
I
K
S
Y
H
L
W
P
S
F
----
T
D
E
Q
W
I
T
I
E
S
Q
M
R
D
L
I
L
T
E
Y
G
R
K
Y
NVNISALTQTESSKNEW
R
K
S
A
I
A
N
T
L
LYLRLK
N
I
Y
V
S
A
D
DFVEE
Q
N
V
Y
V
L
P
K
N
L
L
K
K
F
I
E
I
SDVK
I
Q
V
A
A
F
I
Y
G
M
S
A
KDHPK
V
K
E
I
K
T
V
V
L
V
P
Q
L
G
H
VGSVQISNIPDIGDLPDTEGLELL
G
W
I
H
T
Q
TEELKFMA
A
S
E
V
A
T
H
S
K
L
FADKKRD
C
I
D
I
S
I
FSTPG
S
V
S
L
S
A
Y
N
L
T
D
E
G
Y
Q
W
G
E
E
N
KDIMNVLSEGFEPTF
S
T
H
A
Q
L
L
L
S
DR
I
T
G
N
F
I
I
PSGNVWNYTFMGTAFNQEGD
Y
N
F
K
Y
G
I
P
L
E
FYNEMH
R
P
V
H
F
L
QFS
16
Fugue
46.33
19%
-51
- C4 -
3J6V
-
RT10_BOVIN
J:
[1-201]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
V
R
A
V
F
G
A
L
--
G
R
R
L
W
Q
G
S
K
N
F
S
V
---------------------------------------------------------------------------
S
S
S
R
S
N
I
A
K
N
D
G
-------------
F
L
L
S
T
S
---
M
K
W
V
Q
F
S
N
L
H
V
D
V
P
KDLTK
P
T
I
T
I
-
S
D
E
P
D
T
L
Y
K
R
L
S
V
L
V
K
G
H
D
K
A
V
L
D
S
Y
E
Y
F
A
V
L
-----
A
A
K
E
L
--------
G
I
S
V
K
V
-
H
E
P
P
R
K
I
E
R
F
T
L
L
K
S
V
H
-
I
F
K
K
H
R
V
Q
Y
E
M
----------
R
T
L
Y
R
C
L
E
L
E
-------------
H
L
T
G
S
T
A
---
D
V
Y
L
E
Y
I
Q
R
N
L
P
E
--
G
V
A
M
E
V
T
K
T
R
L
--------------
E
Q
L
P
E
H
I
K
K
P
V
W
E
T
T
P
E
E
K
GDSKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
45.09
22%
-47
- C4 -
1ZY7
2
RED1_HUMAN
A:
[8-402]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SR
Q
P
I
P
SEGLQLHL
P
Q
V
L
A
D
A
V
S
R
--
L
V
L
G
K
F
G
D
L
T
-----
D
N
F
S
S
P
H
A
R
RK
V
L
A
G
V
V
M
-
T
T
G
T
D
V
K
D
A
K
V
I
S
V
S
T
G
T
K
C
I
N
G
E
Y
M
S
DRGLA
L
N
DCH
A
E
I
I
S
R
R
S
L
L
R
F
L
----
Y
T
Q
L
E
L
Y
L
N
N
K
D
D
Q
K
R
SIFQKSERG
G
F
R
L
K
E
N
V
Q
F
H
L
Y
I
S
T
S
P
C
G
D
A
R
-----
I
F
K
A
R
G
Q
L
R
T
K
I
E
S
G
E
G
T
I
P
V
R
S
N
A
S
I
Q
T
W
D
G
V
L
Q
G
E
R
L
L
T
M
S
C
S
D
K
I
A
R
W
N
V
V
G
I
Q
G
S
L
L
S
I
F
V
E
P
-
I
Y
F
S
S
I
I
L
G
S
L
Y
H
G
D
H
L
S
R
A
M
Y
Q
R
ISNIEDLPPL
Y
T
L
N
K
P
L
L
S
G
I
S
N
A
E
A
RQPGKAP
N
F
S
V
N
W
T
VGD
S
A
I
E
V
I
N
A
T
T
G
K
D
EL
G
R
A
S
R
L
C
K
H
A
L
Y
C
R
W
M
R
V
H
-
G
K
V
P
S
H
L
L
R
S
K
I
T
K
P
N
V
Y
H
E
S
K
L
A
A
K
E
Y
Q
A
A
K
A
R
L
F
T
A
F
I
K
A
GL
G
A
W
V
E
K
PTEQDQFSLT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
43.11
14%
-7
- C3 -
1B63
4
MUTL_ECOLI
A:
[3-218]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
P
I
Q
V
L
P
P
Q
L
--
A
N
Q
I
A
A
G
E
V
----
V
E
R
------------------
P
A
-
S
V
V
K
E
L
V
E
N
S
L
D
A
G
-----
A
T
R
I
D
-----
I
D
------
I
E
R
G
----------
G
A
K
L
I
R
I
R
D
N
G
C
-------------
G
I
K
K
D
E
---
L
A
L
A
L
A
R
H
A
T
S
K
I
A
-----
S
L
D
D
L
E
A
I
I
S
L
G
F
R
G
E
A
L
A
S
I
S
S
V
S
R
L
T
L
T
S
R
T
A
E
Q
Q
E
-----
A
W
Q
A
Y
A
E
G
R
D
M
N
V
T
V
K
P
A
A
-
H
P
V
-------------------------
G
----------
T
T
L
E
V
L
D
L
F
Y
-------------
N
T
P
A
R
R
K
---
F
L
R
T
E
K
T
E
F
N
H
I
D
--
E
I
I
R
R
I
A
L
A
R
F
D
V
T
I
N
-
L
S
H
N
G
K
I
V
R
Q
Y
R
A
V
P
E
G
G
Q
K
E
R
R
L
G
A
I
C--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
40.67
15%
-67
- C4 -
1VH4
-
SUFD_ECOLI
A:
[170-254]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
Y
R
H
H
-----
L
D
------
L
A
E
G
A
E
A
T
V
I
----
E
H
F
V
S
L
--
N
D
A
R
-------------
H
F
T
G
A
R
---
F
T
I
N
V
A
A
N
A
H
L
Q
H
I
-----
K
L
A
F
--
E
N
P
L
S
H
H
F
A
H
N
D
L
L
L
A
E
D
A
T
A
F
S
H
S
F
L
L
G
G
A
V
-----
L
R
H
N
T
S
T
Q
L
N
G
E
N
S
T
L
R
I
N
-
S
L
A
M
-
P
V
K
N
E
V
C
D
T
R
T
W
-
L
E
H
N
K
G
F
C
N
S
R
----------
Q
L
H
K
T
I
V
S
D
K
-------------
G
R
A
V
F
N
G
---
L
I
N
V
A
Q
H
A
I
K
T
D
G
--
Q
M
T
N
N
N
L
L
M
G
K
L
A
E
V
D
-
T
K
-
P
Q
L
E
I
Y
A
D
D
V
K
C
S
H
G
A
T
V
G
R
I
D
D
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
35.71
12%
-8
* C3 *
1YVE
4
ILV5_SPIOL
I:
[12-236]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
T
F
D
F
D
S
S
V
FK
K
E
K
V
T
L
S
G
H
D
E
Y
I
V
R
G
G
--
R
N
L
F
P
---
L
L
P
D
A
F
-
K
G
-
I
K
Q
I
G
V
I
G
W
G
S
Q
A
P
A
Q
A
Q
N
L
K
D
S
L
-----
T
E
------
A
K
S
D
V
V
V
K
I
G
LRKG
S
N
S
F
A
E
A
R
A
A
G
F
-------------
S
E
E
N
G
T
-------------------------
L
G
-
D
M
W
E
T
I
S
G
S
D
L
V
L
L
L
I
S
D
S
A
Q
A
D
N
Y
E
K
V
F
S
H
M
-----
K
P
N
S
I
L
G
L
S
H
----------
G
F
L
L
-
G
H
L
Q
S
L
G
Q
D
F
P
K
-
N
------------------------
I
S
V
I
A
V
-------------
C
P
K
G
M
G
P
---
S
V
R
R
L
Y
V
Q
G
K
E
V
N
--
G
A
-
G
I
N
S
S
F
A
V
H
Q
D
V
D
-
G
R
-
A
T
D
V
A
L
G
W
S
I
A
L
G
S
P
F
T
F
A
T
T
L
E
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
26.97
22%
16
- C4 -
4UX3
-
SCC1_YEAST
B:
[25-102]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
L
A
S
N
---
M
S
I
Q
T
H
I
A
E
S
A
K
E
I
-----
A
K
A
---
S
G
C
D
D
E
S
G
D
N
E
Y
I
T
L
R
T
S
G
E
L
L
Q
G
I
V
R
V
Y
S
K
Q
-----
A
T
F
L
L
T
D
I
K
D
T
L
T
K
I
S
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
24.70
19%
-51
- C2 -
2X8N
-
?
A:
[34-81]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
V
---
I
V
F
I
L
A
N
D
R
E
L
K
F
R
-----
P
D
D
L
Q
-
A
T
Y
G
A
T
P
E
Q
L
R
E
I
E
I
S
P
S
G
L
G
V
Y
F
E
T
L
E
E
D
V
S
-----
L
I
G
L
L
E
G
R
R
G
S
A
K
W
M
A
E
H
P
-
L
A
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
24.69
14%
143
- C1 -
2JUB
-
IPI1_BPT4
A:
[21-41]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
V
D
G
E
E
I
K
G
T
-----
V
Y
------
L
G
D
G
W
S
A
K
K
D
----
G
A
T
I
V
I
S
P
A
E
E
T
-------------
A
L
F
K
A
K
---
H
I
S
A
A
H
L
K
I
I
A
K
N
L
-----
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
22.61
33%
185
- C4 -
1T01
-
B:
[1-24]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
P
L
L
Q
A
A
K
G
L
A
--
G
A
V
S
E
L
L
R
S
A
Q
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
22.30
26%
138
* C4 *
1RKC
-
TLN1_CHICK
B:
[1944-1969]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
T
K
K
E
L
I
E
S
A
R
K
V
S
--
E
K
V
S
H
V
L
A
A
L
Q
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
21.10
19%
51
* C5 *
2K6W
-
?
A:
[79-114]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
G
G
Y
H
F
M
L
L
G
L
K
R
P
L
K
A
G
E
E
V
E
L
D
-----
L
L
------
F
A
G
G
K
V
L
K
V
V
----
L
P
V
E
A
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
19.24
9%
33
- C5 -
3ZJA
1
?
A:
[86-120]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
G
N
H
L
M
F
E
K
L
K
Q
Q
P
K
Q
G
Q
S
V
A
V
E
-----
L
H
------
F
A
H
S
D
P
V
A
V
K
----
L
P
V
K
A
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
17.91
11%
57
- C5 -
1ACX
-
A:
[6-32]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
P
A
S
G
A
S
D
G
Q
S
V
S
V
S
-----
V
A
-------
A
A
G
E
T
Y
Y
I
A
----
Q
C
A
P
V
G
G
Q
D
A
C
N
-------------
P
A
T
A
T
S
---
F
T
T
D
A
S
G
A
A
S
F
S
F
V
-----
R
K
S
Y
A
-
G
Q
T
P
S
G
T
P
V
G
S
V
D
C
A
T
D
A
C
N
L
G
A
G
N
S
G
L
N
L
G
H
-----
V
A
L
T
F
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
0.56
13%
301
- C4 -
2XSK
1
?
A:
[75-94]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
P
D
D
R
V
K
I
V
-----
V
T
------
V
S
D
G
Q
S
L
H
L
S
----
Q
Q
W
P
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------