@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0089: (2015-12-12 )
MRKIVLVAIALLISGCASYKITPEHVTSYNNGIQVMTSTQARSKVQLEIAQSKLKGLNESPLVLYVAAQVLEGKPVVFSRKAISVSINQTNLPVLSLRQVMKSSFDFEGILQSFNISVPTAPIDNINMITPPMFYYGQGSFLAYNGMMYGGMGMYGPGFGMMMMDDVEEQEVMQESRQALKILAINYLKKNTLNVENKAKGGFVVVDTKNLKTPGVVVVKVFLEDEIHTFKIDISKM
Atome Classification :
(18 SA)
------------------------.......----------..10........20.---------.......30------........40-----.----------------------------.......---------------50..------..------...-.60------........70..---....--..80.......---.90----......-----..100.......110..--.....120--------..--....-------.---130.......-------.140---.......150.......160------..----.......-----170-----......------...180------......-...190-------........200-----.....-----..210.....-----.--.220..-.....230-.....--------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------M
R
K
I
V
L
V
----------
A
I
A
L
L
I
SGCASYKI
T
---------
P
E
H
V
TSYNN------
G
I
Q
V
M
TSTQA-----R----------------------------
S
K
V
Q
L
E
I
---------------
A
Q
S
K
------LK------GLN-ES
P
------
L
V
L
Y
V
A
A
Q
VLEG---K
P
V
V
--
F
S
R
K
A
I
S
V
S
IN---QTN----L
P
V
L
S
L
-----
R
Q
V
M
K
SSF
D
F
E
G
I
L
Q
S
F--NISVPTAP--------ID--NINM-------I---T-PPM
F
Y
YGQ-------G
S
F
L
---
A
YN
G
M
M
YGGMGMYGPGFG--------
M
M
----
M
MDDV
E
E
-----
Q
-------
E
V
M
Q
E
S
------
R
Q
A
L
--------
K
I
L
A
I
N
-
Y
L
KKN--------TLNVENKAKG
G
-----
F
V
V
V
D-----TKNLKTP
G
V
V
-----
V
--
V
K
V
F
LE-DE
I
H
T
F
K
I
-
D
ISKM--------------------
18
Fugue
87.88
20%
-85
- C5 -
4QTZ
-
?
A:
[1-321]
------------------------
L
G
N
V
V
C
V
T
GASG
Y
I
A
S
W
L
V
R
L
L
L
H
R
G
Y
T
V
K
A
T
VRDPNDPKK
V
D
H
L
V
K
L
D
G
------
A
K
E
R
L
Q
L
F
K
A
-----
N
LLEEGAFDSVVQGCH
G
V
F
HT
A
S
P
F
Y
H
DV
K
D
P
Q
A
E
L
---------------
I
D
P
A
------
L
K
------
G
T
L
-
N
---------
V
L
N
S
C
A
K
S
P
S
L
---
K
R
V
V
--
L
T
S
S
I
A
A
V
A
Y
N
GKP
R
T
P
----
D
V
V
V
D
E
TWFTD
A
D
F
C
A
K
S
N
L
W
Y
V
V
S
K
T
L
--
A
E
E
A
A
W
K
F
--------
V
K
E
N
N
I
D
M
-------
V
---
T
I
N
P
A
M
V
I
G
P
LLQPVLN
T
S
A
A
---
A
I
L
N
L
I
N
G
A
Q
T
F
P
N
A
S
F
G
--------
W
V
----
N
V
K
D
V
A
N
-----
A
-------
H
I
L
A
Y
E
NASASG
R
H
C
L
VE
R
V
A
H
Y
S
E
V
V
R
I
L
-
R
E
L
Y
P
--------
S
L
Q
L
P
E
K
C
A
D
D
KPYV
P
I
Y
Q
V
S
-----
K
E
K
A
K
S
L
G
L
E
-----
Y
T
P
L
E
V
S
I
K
-
E
T
V
E
S
L
K
E
K
K
F
A
N
L
--------------------
22
Fugue
79.83
20%
-66
- C3 -
4LK4
-
?
A:
[10-350]
-----------------RIINGSN
A
N
S
A
E
W
P
----------
S
I
V
A
L
V
K
R
G
A
D
A
Y
Q
G
---------
Q
F
C
G
G
S
F
L
G
------
G
R
Y
V
L
T
A
A
H
C
FDSRS
A
----------------------------
A
S
V
D
V
I
I
GAYDLNNSS
Q
G
E
R
I
A
A
Q
K
I
------
Y
R
------
H
L
S
-
Y
S
P
SNLLND
I
A
I
V
E
L
A
Q
T
S
S
L
---
P
A
I
T
--
L
A
G
P
A
-----
T
---
R
T
S
----
L
P
A
L
T
P
-----
L
T
V
A
G
W
G
I
T
F
T
P
I
L
Q
E
V
--
D
V
D
L
V
S
Q
S
--------
L
C
--
Q
I
V
M
QHGISSD
P
---
N
-
S
T
N
F
C
A
A
R
LTQGDAG
G
P
I
V
---
V
K
T
G
R
E
Q
L
G
I
V
S
W
G
D
E
Q
G
T
Y
G
V
Y
T
NV
S
Y
----
F
R
D
W
I
T
K
-----
H
T
NQLSYD
Q
V
A
N
L
G
------
I
R
P
L
--------
G
K
V
S
Q
S
-
F
T
Y
T
N
LDA
N
A
L
T
Y
T
G
N
T
F
S
S
L
P
A
D
-----
F
S
V
L
S
D
G
C
S
T
K
V
T
L
A
T
G
E
S
C
-----
S
--
V
E
V
A
V
D
A
Q
H
Y
R
Q
Y
Q
Y
-
D
F
E
L
I
F
S
Y
AG
G
S
K
R
A
T
S
R
I
Q
L
D
T--
2
PsiBlast_PDB
71.30
23%
-61
- C6 -
1GNL
1
HCP_DESDA
A:
[422-539]
--------------------------------------------
I
L
T
A
G
C
A
K
Y
R
Y
N
---------
K
L
N
L
G
D
I
G
G
------
I
P
R
V
L
D
A
G
Q
C
-----
N
----------------------------
D
S
Y
S
L
A
V
---------------
I
A
L
K
------
L
K
E
V
F
GLE
D
V
N
-
D
L
P
------
I
V
Y
N
I
A
W
--
Y
E
Q
---
K
A
V
I
--
V
L
L
A
L
L
S
L
G
V
K
---
N
I
H
L
G
PT
L
P
A
F
L
S
-----
P
N
V
A
K
V
------
L
V
E
Q
F
--
N
I
G
G
I
T
S
P
--------
Q
D
--
D
L
K
A
-------
F
---
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
71.13
23%
-55
- C6 -
1OA0
2
HCP_DESDA
A:
[422-539]
--------------------------------------------
I
L
T
A
G
C
A
K
Y
R
Y
N
---------
K
L
N
L
G
D
I
G
G
------
I
P
R
V
L
D
A
G
Q
C
-----
N
----------------------------
D
S
Y
S
L
A
V
---------------
I
A
L
K
------
L
K
E
V
F
GLE
D
V
N
-
D
L
P
------
I
V
Y
N
I
A
W
--
Y
E
Q
---
K
A
V
I
--
V
L
L
A
L
L
S
L
G
V
K
---
N
I
H
L
G
PT
L
P
A
F
L
S
-----
P
N
V
A
K
V
------
L
V
E
Q
F
--
N
I
G
G
I
T
S
P
--------
Q
D
--
D
L
K
A
-------
F
---
F
-
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
70.95
23%
-59
- C6 -
1UPX
2
HCP_DESDA
A:
[422-539]
--------------------------------------------
I
L
T
A
G
C
A
K
Y
R
Y
N
---------
K
L
N
L
G
D
I
G
G
------
I
P
R
V
L
D
A
G
Q
C
-----
N
----------------------------
D
S
Y
S
L
A
V
---------------
I
A
L
K
------
L
K
E
V
F
GLE
D
V
N
-
D
L
P
------
I
V
Y
N
I
A
W
--
Y
E
Q
---
K
A
V
I
--
V
L
L
A
L
L
S
L
G
V
K
---
N
I
H
L
G
PT
L
P
A
F
L
S
-----
P
N
V
A
K
V
------
L
V
E
Q
F
--
N
I
G
G
I
T
S
P
--------
Q
D
--
D
L
K
A
-------
F
---
F
-
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
65.07
11%
-56
- C6 -
2A8J
1
TASP1_HUMAN
A:
[41-416]
G
G
F
V
L
V
H
A
GAGYHSESK
A
K
E
Y
K
H
V
C
K
R
A
C
Q
K
----------
A
I
E
K
L
Q
A
G
A
L
A
T
D
A
V
---------
T
A
A
L
V
E
L
E
D
SPFTNA
G
M
G
S
N
L
N
L
L
G
-----
E
----------------------------
I
E
C
D
A
S
I
---------------
M
D
G
K
SL
N
F
G
A
V
G
------
A
L
S
-
G
I
K
------
N
P
V
S
V
A
N
R
L
L
C
E
---
G
Q
K
G
--
K
L
G
R
I
P
P
C
F
L
V
---
G
E
G
----
A
Y
R
W
A
V
-----
D
H
G
I
P
S
C
P
T
V
G
A
V
V
V
D
H
EG
N
V
A
A
A
V
S
S
--------
G
G
--
L
A
L
K
-------
H
PGR
V
-
G
Q
A
A
L
Y
G
C
-------
G
C
W
A
E
N
T
G
A
H
N
P
Y
S
T
A
V
S
T
S
G
C
G
E
H
--------
L
V
R
T
I
L
A
R
E
C
S
H
A
-----
L
-------
Q
A
E
D
A
H
------
Q
A
L
L
--------
E
T
M
Q
N
K
-
F
I
S
S
P
--------
F
L
A
S
E
D
G
V
L
G
G
-----
V
I
V
L
R
-----
S
C
L
L
V
E
F
L
W
S
H
TTE
S
M
--
C
V
G
Y
M
S
-
A
Q
D
G
K
A
K
T
-
H
I
S
R
L
P
PGAVAGQ
S
V
A
I
E
G
G
V
C
R
L
E
1
PsiBlast_PDB
60.87
23%
-11
- C6 -
1GN9
1
HCP_DESDA
A:
[424-539]
--------------------------------------------
I
L
T
A
G
C
A
K
Y
R
Y
N
---------
K
L
N
L
G
D
I
G
G
------
I
P
R
V
L
D
A
G
Q
C
-----
N
----------------------------
D
S
Y
S
L
A
V
---------------
I
A
L
K
------
L
K
E
V
F
GLE
D
V
N
-
D
L
P
------
I
V
Y
N
I
A
W
--
Y
E
Q
---
K
A
V
I
--
V
L
L
A
L
L
S
L
G
V
K
---
N
I
H
L
G
PT
L
P
A
F
L
S
-----
P
N
V
A
K
V
------
L
V
E
Q
F
--
N
I
G
G
I
T
S
P
--------
Q
D
--
D
L
K
A
-------
F
---
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
57.19
11%
-42
- C4 -
3GQQ
2
U119A_HUMAN
A:
[12-192]
---------------------------------------------------
K
Q
P
I
G
---------
P
E
D
V
L
G
L
Q
R
------
I
T
G
D
Y
L
C
S
P
E
-----
E
----------------------------
N
I
Y
K
I
D
F
---------------
V
R
F
K
------
I
R
--------
D
M
D
S
G
------
T
V
L
F
E
I
K
K
P
P
N
A
---
G
R
F
V
--
R
Y
Q
-------------------------------
F
T
P
A
F
L
R
L
R
Q
V
G
A
T
V
--
E
F
T
V
G
D
K
P
--------
V
N
--
N
----------
F
---
R
M
I
E
R
H
Y
F
R
N
-------
Q
L
L
K
---
S
F
D
-----------
F
H
F
G
--------
F
C
----
I
P
S
S
K
N
T
-----
C
-------
E
H
I
Y
D
F
------
P
P
L
S
--------
E
E
L
I
S
E
M
I
--------------------
R
H
P
-----
Y
E
T
Q
S
-----
D
S
F
Y
F
V
D
D
R
L
-----
V
--
M
------
H
N
K
A
D
Y
S
Y
-
S
------------------------
20
Fugue
54.27
12%
-38
- C6 -
2KCW
-
YJAB_ECOLI
A:
[1-147]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
I
-----
S
I
R
R
S
R
H
E
E
G
E
E
L
V
A
I
W
--
C
R
S
V
D
A
T
H
DFLS
A
E
Y
R
T
E
--
L
E
D
L
-------
V
---
R
-
S
F
L
P
E
A
P
L
-------
W
V
A
V
---
N
E
R
D
Q
P
V
G
F
M
L
L
S
G
Q
H
M
D
--------
A
L
----
F
I
D
P
D
V
R
GCG
V
G
R
-------
V
L
V
E
H
A
------
L
S
M
A
--------
P
E
L
T
T
N
-
V
N
E
Q
N
--------
E
Q
A
V
G
F
Y
K
K
V
G
-----
F
K
V
T
G
-----
R
S
E
V
D
D
L
G
K
P
-----
Y
--
P
L
L
N
L
A
-
Y
V
G
A
------------------------------
17
Fugue
52.88
15%
-50
- C6 -
3UX4
2
UREI_HELPJ
A:
[1-195]
------------------------
M
L
G
L
V
L
L
----------
Y
V
G
I
V
L
I
S
N
G
I
C
G
L
---------------------------------------------------------------------------------------------
T
K
------
V
D
------
P
K
S
-
T
A
V
------
M
N
F
F
V
G
G
L
S
I
V
C
---
N
V
V
V
--
I
T
Y
S
A
L
H
P
T
-------------
A
P
S
F
Y
-----
G
P
A
T
G
L
L
F
G
F
T
Y
L
Y
A
A
I
--
N
H
T
F
------------------
G
L
-------
D
---
W
-
R
P
Y
S
W
Y
S
L
---------
F
V
---
A
I
N
T
V
P
A
A
I
L
S
H
Y
S
D
M
L
D
--------
D
H
----
K
V
L
G
I
T
E
-----
G
-------
D
W
W
A
I
I
------
W
L
A
W
--------
G
V
L
W
L
T
-
A
F
I
E
N
--------
I
L
K
I
P
L
G
K
F
----------------------
T
P
W
L
A
-----
I
--
I
E
G
I
L
T
-
A
W
I
P
A
W
L
L
-
F
I
Q
H
W
V-------------------
19
Fugue
46.29
17%
19
- C6 -
3SHG
1
VBHA_BARSR
B:
[1-61]
--------------------------------------------------------------------------------
V
L
S
E
E
E
I
E
Y
R
-----
R
----------------------------
R
D
A
R
N
A
L
---------------
A
S
Q
R
------
L
E
------
G
L
E
-
P
D
P
------
Q
V
V
A
Q
M
E
R
V
V
V
G
ELE
T
S
D
V
--
I
K
D
L
M
E
R
I
K
R
E
---
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
40.28
28%
118
- C6 -
1F93
-
HNF1A_MOUSE
H:
[5-30]
-----------------------------------------------------------------------------------------------
L
----------------------------
S
Q
L
Q
T
E
L
---------------
L
A
A
L
------
L
E
S-----
G
L
S
-
K
E
A
------
L
I
Q
A
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
36.70
26%
176
* C6 *
2XZE
-
CHMP3_HUMAN
Q:
[18-40]
-------------------------------------------------------------------------------------
S
E
D
E
E
-----
E
----------------------------
E
E
E
A
L
E
A
---------------
M
Q
S
R
------
L
A
------
T
L
R
-
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
35.67
14%
51
- C6 -
2JMK
-
?
A:
[41-75]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
------
T
D
V
M
--------
M
D
F
I
S
R
-
F
A
R
T
D
--------
E
I
M
P
-
E
D
K
T
V
G
-----
F
V
V
V
N
-----
A
D
K
K
L
M
S
V
S
F
-----
S
--
D
I
D
E
N
M
-
K
K
V
I
K
A
T
A
-
E
K
F
K
N
--------------------
23
Fugue
29.67
30%
127
- C6 -
2WAX
2
EDC3_HUMAN
B:
[13-42]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
I
P
D
T
D
F
D
F
E
G
N
L
A
L
F
--
D
K
A
A
V
F
E
E
--------
I
D
--
T
Y
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
26.20
14%
27
- C2 -
3ISY
-
IPI_BACSU
A:
[5-42]
----------------------------------------------------------------------------------------------------------------------------
Q
E
V
V
L
S
I
---------------
D
A
I
Q
----------------
E
-
P
E
Q
------
I
K
F
N
M
S
L
K
N
Q
S
E
---
R
A
I
E
F
Q
F
S
T
G
Q
K
F
E
L
V
V
---
Y
D
S
----
E
H
K
E
R
Y
-----
R
Y
S
K
E
K
M
F
T
Q
A
F
Q
N
L
T
L
--
E
S
G
E
T
Y
D
F
--------
S
D
--
V
W
K
E
-------
V
---
P
-
E
P
G
T
Y
E
V
K
-------
V
T
F
K
---
G
R
A
E
N
L
K
Q
V
Q
A
V
Q
Q
F
E
V
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
16.26
7%
110
- C6 -
2AP3
-
?
A:
[2-29]
------------------------------
H
----------
M
G
I
Q
R
P
T
S
T
T
T
D
K
------------
K
E
I
K
A
Y
L
K
------
Q
V
D
K
I
K
D
D
E
E
-----
P
----------------------------
I
K
T
V
G
K
K
---------------
I
A
E
L
------
D
E
------
K
K
K
-
K
L
T
------
E
D
V
N
S
K
D
T
A
V
R
G
---
K
A
V
K
--
D
L
I
K
N
A
D
D
R
L
K
---
E
F
E
----
K
E
E
D
A
I
-----
K
K
S
E
Q
D
F
K
K
A
D
N
I
D
N
D
V
--
K
R
K
E
V
K
Q
L
--------
D
D
--
V
L
K
E
-------
K
---
Y
-
K
L
H
S
D
Y
A
K
-------
A
Y
K
K
---
A
V
N
S
E
K
T
L
F
K
Y
L
N
Q
N
D
A
T
--------
Q
Q
----
G
V
N
E
K
S
K
-----
A
-------
I
E
Q
N
Y
K
------
K
L
K
E
--------
V
S
D
K
Y
T
-
K
V
L
N
K
--------
V
Q
K
E
K
Q
D
V
D
----------------------------------------------------------------------------
12
HHSearch
15.55
14%
590
- C1 -
3GLW
-
?
Z:
[7-18]
--------------------------------------------------
Q
T
Q
T
T
P
---------
P
K
E
T
L
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------