@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0097: (2015-12-12 )
MKMNVESFNLDHTKVKAPYVRIADRKKGVNGDLIVKYDVRFKQPNRDHMDMPSLHSLEHLVAEIIRNHANYVVDWSPMGCQTGFYLTVLNHDNYTEILEVLEKTMQDVLKAKEVPASNEKQCGWAANHTLEGAQNLARAFLDKRAEWSEVGV
Atome Classification :
(20 SA)
------------------------------.........10........20-........30........40........50........60........--70---.-----........80........90.-.......100........---110--..---......120.......130.......140.......150----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------MKMNVESFNLDHTKVKA
P
Y
V
R
-
I
ADRKKGVNG
D
L
I
V
K
Y
D
V
R
FKQPNRDHMDM
P
S
L
H
S
L
E
H
L
V
A
E
I
I
R
NHA--
N
----
Y
-----
V
V
DWSPMGCQT
G
F
Y
L
T
V
LNHD-
N
Y
T
E
I
L
E
V
L
-
E
K
T
M
Q
D
V
L
---
K
A
---KE---VPASNEKQCGWAANH
T
L
E
G
A
Q
N
L
A
R
A
F
L
DKRAEWSEVGV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
97.73
100%
-108
- C3 -
1J6X
4
LUXS_HELPJ
A:
[1-151]
------------------------------
M
K
M
N
V
E
S
F
N
L
D
H
T
K
V
K
A
P
Y
V
R
-
I
A
D
R
K
K
G
V
N
G
D
L
I
V
K
Y
D
V
R
F
K
Q
P
N
R
D
H
M
D
M
P
S
L
H
S
L
E
H
L
V
A
E
I
I
R
N
H
A
--
N
----
Y
-----
V
V
D
W
S
P
M
G
C
Q
T
G
F
Y
L
T
V
L
N
H
D
-
N
Y
T
E
I
L
E
V
L
-
E
K
T
M
Q
D
V
L
---
K
A
---
K
E
---
V
P
A
S
N
E
K
Q
C
G
W
A
A
N
H
T
L
E
G
A
Q
N
L
A
R
A
F
L
D
K
R
A
E
W
S
E
V
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
96.83
96%
-108
- C3 -
1J6X
4
LUXS_HELPJ
A:
[2-151]
-------------------------------
K
M
N
V
E
S
F
N
L
D
H
T
K
V
K
A
P
Y
V
R
-
I
A
D
R
K
K
G
V
N
G
D
L
I
V
K
Y
D
V
R
F
K
Q
P
N
R
D
H
M
D
M
P
S
L
H
S
L
E
H
L
V
A
E
I
I
R
N
H
A
--
N
----
Y
-----
V
V
D
W
S
P
M
G
C
Q
T
G
F
Y
L
T
V
L
N
H
D
-
N
Y
T
E
I
L
E
V
L
-
E
K
T
M
Q
D
V
L
---
K
A
---
K
E
---
V
P
A
S
N
E
K
Q
C
G
W
A
A
N
H
T
L
E
G
A
Q
N
L
A
R
A
F
L
D
K
R
A
E
W
S
E
V
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
80.30
43%
-93
- C3 -
1VH2
1
LUXS_DEIRA
A:
[7-153]
----------------------------------
V
E
S
F
D
L
D
H
T
K
V
K
A
P
Y
V
R
-
L
A
G
V
K
T
T
P
K
G
D
Q
I
S
K
Y
D
L
R
F
L
Q
P
N
Q
G
A
I
D
P
A
A
I
H
T
L
E
H
L
L
A
G
Y
M
R
D
H
L
--
E
----
G
-----
V
V
D
V
S
P
M
G
C
R
T
G
M
Y
M
A
V
I
G
E
P
-
D
E
Q
G
V
M
K
A
F
-
E
A
A
L
K
D
T
A
---
G
H
---
D
Q
P--
I
P
G
V
S
E
L
E
C
G
N
Y
R
D
H
D
L
A
A
A
R
Q
H
A
R
D
V
L
D
Q
G
L
K
V
Q
E
T
I
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
79.95
43%
-91
- C3 -
1INN
2
LUXS_DEIRA
A:
[6-153]
---------------------------------
N
V
E
S
F
D
L
D
H
T
K
V
K
A
P
Y
V
R
-
L
A
G
V
K
T
T
P
K
G
D
Q
I
S
K
Y
D
L
R
F
L
Q
P
N
Q
G
A
I
D
P
A
A
I
H
T
L
E
H
L
L
A
G
Y
M
R
D
H
L
--
E
----
G
-----
V
V
D
V
S
P
M
G
C
R
T
G
M
Y
M
A
V
I
G
E
P
-
D
E
Q
G
V
M
K
A
F
-
E
A
A
L
K
D
T
A
---
G
H
---
D
Q
P--
I
P
G
V
S
E
L
E
C
G
N
Y
R
D
H
D
L
A
A
A
R
Q
H
A
R
D
V
L
D
Q
G
L
K
V
Q
E
T
I
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
79.83
43%
-93
- C3 -
1J6V
1
LUXS_DEIRA
A:
[7-153]
----------------------------------
V
E
S
F
D
L
D
H
T
K
V
K
A
P
Y
V
R
-
L
A
G
V
K
T
T
P
K
G
D
Q
I
S
K
Y
D
L
R
F
L
Q
P
N
Q
G
A
I
D
P
A
A
I
H
T
L
E
H
L
L
A
G
Y
M
R
D
H
L
--
E
----
G
-----
V
V
D
V
S
P
M
G
C
R
T
G
M
Y
M
A
V
I
G
E
P
-
D
E
Q
G
V
M
K
A
F
-
E
A
A
L
K
D
T
A
---
G
H
---
D
Q
P--
I
P
G
V
S
E
L
E
C
G
N
Y
R
D
H
D
L
A
A
A
R
Q
H
A
R
D
V
L
D
Q
G
L
K
V
Q
E
T
I
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
79.43
47%
-95
- C3 -
2FQO
3
LUXS_BACSU
A:
[4-150]
----------------------------------
V
E
S
F
E
L
D
H
N
A
V
V
A
P
Y
V
R
H
C
G
V
H
K
V
G
T
D
G
-
V
V
N
K
F
D
I
R
F
C
Q
P
N
K
Q
A
M
K
P
D
T
I
H
T
L
E
H
L
L
A
F
T
I
R
S
H
A
--
E
----
K
YDHFD
I
I
D
I
S
P
M
G
C
Q
T
G
Y
Y
L
V
V
S
G
E
P
-
T
S
A
E
I
V
D
L
L
-
E
D
T
M
K
E
A
V
---
E
I
---
T
E
---
I
P
A
A
N
E
K
Q
C
G
Q
A
K
L
H
D
L
E
G
A
K
R
L
M
R
F
W
L
S
Q
D
K
E
E
L
L
K
V
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
79.00
46%
-95
- C3 -
1YCL
3
LUXS_BACSU
A:
[3-149]
----------------------------------
V
E
S
F
E
L
D
H
N
A
V
V
A
P
Y
V
R
H
C
G
V
H
K
V
G
T
D
G
-
V
V
N
K
F
D
I
R
F
C
Q
P
N
K
Q
A
M
K
P
D
T
I
H
T
L
E
H
L
L
A
F
T
I
R
S
H
A
--
E
----
K
YDHFD
I
I
D
I
S
P
M
G
A
Q
T
G
Y
Y
L
V
V
S
G
E
P
-
T
S
A
E
I
V
D
L
L
-
E
D
T
M
K
E
A
V
---
E
I
---
T
E
---
I
P
A
A
N
E
K
Q
C
G
Q
A
K
L
H
D
L
E
G
A
K
R
L
M
R
F
W
L
S
Q
D
K
E
E
L
L
K
V
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
78.48
47%
-92
- C3 -
2FQT
4
LUXS_BACSU
A:
[4-150]
----------------------------------
V
E
S
F
E
L
D
H
N
A
V
V
A
P
Y
V
R
H
C
G
V
H
K
V
G
T
D
G
-
V
V
N
K
F
D
I
R
F
C
Q
P
N
K
Q
A
M
K
P
D
T
I
H
T
L
E
H
L
L
A
F
T
I
R
S
H
A
--
E
----
K
YDHFD
I
I
D
I
S
P
M
G
C
Q
T
G
Y
Y
L
V
V
S
G
E
P
-
T
S
A
E
I
V
D
L
L
-
E
D
T
M
K
E
A
V
---
E
I
---
T
E
---
I
P
A
A
N
E
K
Q
C
G
Q
A
K
L
H
D
L
E
G
A
K
R
L
M
R
F
W
L
S
Q
D
K
E
E
L
L
K
V
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
77.17
38%
-92
- C3 -
1J6W
4
LUXS_HAEIN
A:
[3-153]
---------------------------------
L
L
D
S
F
K
V
D
H
T
K
M
N
A
P
A
V
R
-
I
A
K
T
M
L
T
P
K
G
D
N
I
T
V
F
D
L
R
F
C
I
P
N
K
E
I
L
S
P
K
G
I
H
T
L
E
H
L
F
A
G
F
M
R
D
H
L
NG
D
SI--
E
-----
I
I
D
I
S
P
M
G
C
R
T
G
F
Y
M
S
L
I
G
T
P
-
N
E
Q
K
V
S
E
A
W
-
L
A
S
M
Q
D
V
L
G
VQ
D
Q
---
A
S
---
I
P
E
L
N
I
Y
Q
C
G
S
Y
T
E
H
S
L
E
D
A
H
E
I
A
K
N
V
I
A
R
G
I
G
V
N
K
N
E
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_CBE
75.08
35%
-97
- C3 -
4XCH
1
?
D:
[46-182]
---------------------------------------
L
D
H
T
I
V
K
A
P
Y
I
R
-
L
I
S
E
E
V
G
P
K
G
D
I
I
T
N
F
D
I
R
L
I
Q
P
N
E
N
A
M
D
T
A
G
L
H
T
I
E
H
L
L
A
K
L
I
R
Q
R
I
--
D
----
G
-----
L
I
D
C
S
P
F
G
C
R
T
G
F
H
M
I
M
W
G
K
Q
-
D
S
E
K
I
A
Q
V
I
-
K
S
S
L
E
E
I
A
---
E
G
ITW
E
D
---
V
P
G
T
T
I
E
S
C
G
N
Y
K
D
H
S
L
H
S
A
K
E
W
A
K
L
I
L
S
Q
G
I
S
T
D
A
F
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_CBE
75.05
35%
-103
- C3 -
4XCH
1
?
B:
[46-182]
---------------------------------------
L
D
H
T
I
V
K
A
P
Y
I
R
-
L
I
S
E
E
V
G
P
K
G
D
I
I
T
N
F
D
I
R
L
I
Q
P
N
E
N
A
M
D
T
A
G
L
H
T
I
E
H
L
L
A
K
L
I
R
Q
R
I
--
D
----
G
-----
L
I
D
C
S
P
F
G
C
R
T
G
F
H
M
I
M
W
G
K
Q
-
D
S
E
K
I
A
Q
V
I
-
K
S
S
L
E
E
I
A
---
E
G
ITW
E
D
---
V
P
G
T
T
I
E
S
C
G
N
Y
K
D
H
S
L
H
S
A
K
E
W
A
K
L
I
L
S
Q
G
I
S
T
D
A
F
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
74.96
35%
-97
- C3 -
4XCH
1
?
A:
[46-182]
---------------------------------------
L
D
H
T
I
V
K
A
P
Y
I
R
-
L
I
S
E
E
V
G
P
K
G
D
I
I
T
N
F
D
I
R
L
I
Q
P
N
E
N
A
M
D
T
A
G
L
H
T
I
E
H
L
L
A
K
L
I
R
Q
R
I
--
D
----
G
-----
L
I
D
C
S
P
F
G
C
R
T
G
F
H
M
I
M
W
G
K
Q
-
D
S
E
K
I
A
Q
V
I
-
K
S
S
L
E
E
I
A
---
E
G
ITW
E
D
---
V
P
G
T
T
I
E
S
C
G
N
Y
K
D
H
S
L
H
S
A
K
E
W
A
K
L
I
L
S
Q
G
I
S
T
D
A
F
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_CBE
74.77
35%
-99
- C3 -
4XCH
1
?
C:
[46-182]
---------------------------------------
L
D
H
T
I
V
K
A
P
Y
I
R
-
L
I
S
E
E
V
G
P
K
G
D
I
I
T
N
F
D
I
R
L
I
Q
P
N
E
N
A
M
D
T
A
G
L
H
T
I
E
H
L
L
A
K
L
I
R
Q
R
I
--
D
----
G
-----
L
I
D
C
S
P
F
G
C
R
T
G
F
H
M
I
M
W
G
K
Q
-
D
S
E
K
I
A
Q
V
I
-
K
S
S
L
E
E
I
A
---
E
G
ITW
E
D
---
V
P
G
T
T
I
E
S
C
G
N
Y
K
D
H
S
L
H
S
A
K
E
W
A
K
L
I
L
S
Q
G
I
S
T
D
A
F
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_CBE
73.95
39%
-87
- C3 -
1JOE
3
LUXS_HAEIN
D:
[9-144]
---------------------------------------
V
D
H
T
K
M
N
A
P
A
V
R
-
I
A
K
T
M
L
T
P
K
G
D
N
I
T
V
F
D
L
R
F
C
I
P
N
K
E
I
L
S
P
K
G
I
H
T
L
E
H
L
F
A
G
F
M
R
D
H
L
--
N
GDSI
E
-----
I
I
D
I
S
P
M
G
C
R
T
G
F
Y
M
S
L
I
G
T
P
-
N
E
Q
K
V
S
E
A
W
-
L
A
S
M
Q
D
V
L
---
G
V
---
Q
D
QAS
I
P
E
L
N
I
Y
Q
C
G
S
Y
T
E
H
S
L
E
D
A
H
E
I
A
K
N
V
I
A
R
G
I
G
V
N
K
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
73.63
38%
-86
- C3 -
1J6W
4
LUXS_HAEIN
A:
[4-144]
----------------------------------
L
D
S
F
K
V
D
H
T
K
M
N
A
P
A
V
R
-
I
A
K
T
M
L
T
P
K
G
D
N
I
T
V
F
D
L
R
F
C
I
P
N
K
E
I
L
S
P
K
G
I
H
T
L
E
H
L
F
A
G
F
M
R
D
H
L
--
N
GDSI
E
-----
I
I
D
I
S
P
M
G
C
R
T
G
F
Y
M
S
L
I
G
T
P
-
N
E
Q
K
V
S
E
A
W
-
L
A
S
M
Q
D
V
L
---
G
V
---
Q
D
QAS
I
P
E
L
N
I
Y
Q
C
G
S
Y
T
E
H
S
L
E
D
A
H
E
I
A
K
N
V
I
A
R
G
I
G
V
N
K
N
E
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_CBE
73.24
39%
-91
- C3 -
1JOE
3
LUXS_HAEIN
C:
[9-144]
---------------------------------------
V
D
H
T
K
M
N
A
P
A
V
R
-
I
A
K
T
M
L
T
P
K
G
D
N
I
T
V
F
D
L
R
F
C
I
P
N
K
E
I
L
S
P
K
G
I
H
T
L
E
H
L
F
A
G
F
M
R
D
H
L
--
N
GDSI
E
-----
I
I
D
I
S
P
M
G
C
R
T
G
F
Y
M
S
L
I
G
T
P
-
N
E
Q
K
V
S
E
A
W
-
L
A
S
M
Q
D
V
L
---
G
V
---
Q
D
QAS
I
P
E
L
N
I
Y
Q
C
G
S
Y
T
E
H
S
L
E
D
A
H
E
I
A
K
N
V
I
A
R
G
I
G
V
N
K
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_CBE
72.70
39%
-92
- C3 -
1JOE
2
LUXS_HAEIN
B:
[9-144]
---------------------------------------
V
D
H
T
K
M
N
A
P
A
V
R
-
I
A
K
T
M
L
T
P
K
G
D
N
I
T
V
F
D
L
R
F
C
I
P
N
K
E
I
L
S
P
K
G
I
H
T
L
E
H
L
F
A
G
F
M
R
D
H
L
--
N
GDSI
E
-----
I
I
D
I
S
P
M
G
C
R
T
G
F
Y
M
S
L
I
G
T
P
-
N
E
Q
K
V
S
E
A
W
-
L
A
S
M
Q
D
V
L
---
G
V
---
Q
D
QAS
I
P
E
L
N
I
Y
Q
C
G
S
Y
T
E
H
S
L
E
D
A
H
E
I
A
K
N
V
I
A
R
G
I
G
V
N
K
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
72.35
39%
-87
- C3 -
1JOE
3
LUXS_HAEIN
A:
[9-144]
---------------------------------------
V
D
H
T
K
M
N
A
P
A
V
R
-
I
A
K
T
M
L
T
P
K
G
D
N
I
T
V
F
D
L
R
F
C
I
P
N
K
E
I
L
S
P
K
G
I
H
T
L
E
H
L
F
A
G
F
M
R
D
H
L
--
N
GDSI
E
-----
I
I
D
I
S
P
M
G
C
R
T
G
F
Y
M
S
L
I
G
T
P
-
N
E
Q
K
V
S
E
A
W
-
L
A
S
M
Q
D
V
L
---
G
V
---
Q
D
QAS
I
P
E
L
N
I
Y
Q
C
G
S
Y
T
E
H
S
L
E
D
A
H
E
I
A
K
N
V
I
A
R
G
I
G
V
N
K
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
54.49
25%
-63
- C3 -
4RIC
5
FAN1_HUMAN
A:
[1-631]
TGHP
Y
Y
L
R
S
F
L
V
V
L
K
T
V
L
E
N
E
D
D
M
L
L
F
D
E
Q
E
K
G
I
V
T
K
F
Y
Q
L
S
A
T
G
Q
K
L
Y
V
R
-
L
F
Q
R
K
L
----
S
W
I
K
M
T
K
L
E
Y
E
E
I
A
L
D
---------
L
T
P
V
I
E
E
L
T
N
A
--------------------------
G
F
L
Q
T
E
S
E
L
Q
-
E
L
S
E
V
L
E
L
L
S
A
P
E
L
K
S
L
A
---
K
T
---
F
H
---
L
V
N
P
N
G
Q
------------
K
Q
Q
L
V
D
A
F
L
K
L
A
K
Q
R
S
V
I
G
A
V
I
L
K
R
A
K
A
L
A
G
Q
S
V
R
I
C
K
G
P
R
A
V
F
S
R
I
L
L
L
F
S
LTDSMEDEDAACGGQGQLS
T
V
L
L
V
NLGR
M
E
F
P
S
Y
T
I
N
R
K
T
HIFQD
R
D
D
L
I
R
Y
A
A
A
T
H
M
L
S
D
I
S
S
A
M
A
N
GN
W
E
E
A
K
E
L
A
Q
C
A
K
R
D
W
N
R
L
KNH
P
S
L
R
C
H
E
D
LP
L
F
L
R
C
F
T
V
G
W
I
Y
T
R
I
L
S
R
F
V
E
I
L
Q
R
L
HM
Y
E
E
A
V
R
E
L
E
S
L
L
S
Q
RIYCPDS
R
G
R
W
W
D
R
L
A
L
N
L
H
QHLKR
L
E
P
T
I
K
C
I
T
E
G
L
A
DPEVRT
G
H
R
L
S
L
Y
Q
R
A
V
R
L
R
E
SPSCKKFKHLFQQLPEM
A
V
Q
D
V
K
H
V
T
I
T
G
R
L
CK
S
V
F
V
MVLCS
V
E
E
L
A
L
A
H
Y
R
R
S
GFDQGIHGE
G
S
T
F
S
T
L
Y
G
L
L
L
W
DIIFMDGIPDVFRNACQAFPLDLCTDS
F
F
T
S
R
R
P
A
L
E
A
R
L
Q
L
I
H
D
AP
E
E
S
L
R
A
W
V
A
A
T
W
H
E
Q
EGRVASLVSWDRFTS
L
Q
Q
A
Q
D
L
V
S
C
L
G
G
P
V
L
S
G
V
C
R
H
L
A
A
DFRHCRGGLPD
L
V
V
W
N
SQSR
H
F
K
L
V
E
V
K
G
PNDRLS
H
K
Q
M
I
W
L
A
E
L
Q
K
L
G
A
E
V
E
V
C
H
V
V
A
V
30
HHSearch
48.74
28%
-122
* C3 *
1QF6
-
SYT_ECOLI
A:
[69-128]
---------------------------------------------------------------------------------
E
I
I
R
H
S
C
A
H
L
L
G
H
A
I
K
Q
L
W
P-
H
----
T
-----
K
M
A
I
G
P
V
I
-
D
N
G
F
Y
Y
D
V
D
L
D
R
T
L
T
Q
E
D
V
E
A
L
-
E
K
R
M
H
E
L
A
---
E
K
---
N
Y
---
D
V
I
K
K
K
V
S
W
H
E
A
R
E
T
F
A
N
R
G
E
S
Y
K
V
S
I
L
D
E
N
I
A
H
D
D
K
P
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------