@TOME V2.3
(Nov 2016)

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3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : jhp_0099: (2015-12-12 )
MILTAMQDAIGRTPIFKFTRKDYPIPLKSAIYAKLEHLNPGGSVKDRLGQYLIKEAFRTRKITSTTTIIEPTAGNTGIALALVAIKHHLKTIFVVPKKFSTEKQQIMRALGALVINTPTSEGISGAIKKSKELAESIPDSYLPLQFENPDNPAAYYHTLAPEIVQELGTNLTSFVAGIGSGGTFAGMAKYLKERIPNIRLIGVEPEGSILNGGEPGPHEIEGIGVEFIPPFFANLDIDRFETISDEEGFSYTRKLAKKNGLLVGSSSGAAFAAALKEVQRLPEGSQVLTIFPDMADRYLSKGIYS

Atome Classification :

(67 SA) -------------------------------------.........10........-20....-...----.-.30........40........50........60..---.--.-...-.70........80........90........100.......110.......120-...---...---...130.....-..140..-.-.....150.......160.......-170.......180.......190...--....200-....-...-----.------210----...-----.------.....220.......230....---...240--.---.......250.......260.......270....-...280-.-.--...--...290.......300...----------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) -------------------------------------MILTAMQDAIGRTPIFKFT-R-KDYP-IPL----K-SAIYAKLEHLNPGGSVKDRLGQYLIKEAFRTRKIT---S--T-TTI-IEPTAGNTGIALALVAIKHHLKTIFVVPKKFSTEKQQIMRALGALVINTPTS---EGI---SGA---IKKSKELAESI-PDSY-LP-L-QFENPDNPAAYYHTLAPEIVQELGT-NLTSFVAGIGSGGTFAGMAKYLKERI--PNIRLI--GVEP-EGS-----I------L------NGG-----E------PGPHEIEGIGVEFIPPFFANLD---IDRFE---T---ISDEEGFSYTRKLAKKNGLLVGSSSGAAFAAALK-EVQR-L-P-E--GSQ--VLTIFPDMADRYLSKGIYS----------------------------------------------------------------------------------------------------------------------------------------------------------
1 PsiBlast_PDB 98.1993% -76 - C3 -4R2V - CYSM_HELPY A:[2-305] -------------------------------------MIITTMQDAIGRTPVFKFT-N-KDYP-IPL----N-SAIYAKLEHLNPGGSVKDRLGQYLIEEGFKTGKIT---S--K-TTI-IEPTAGNTGIALALVAIKHHLKTIFVVPEKFSTEKQQIMRALGALVINTPTS---EGI---SGA---IKKSKELAESI-PDSY-LP-L-QFENPDNPAAYYHTLAPEIVQELGT-NLTSFVAGIGSGGTFAGTARYLKERI--PAIRLI--GVEP-EGS-----I------L------NGG-----E------PGPHEIEGIGVEFIPPFFENLD---IDGFE---T---ISDEEGFSYTRKLAKKNGLLVGSSSGAAFVAALK-EAQR-L-P-E--GSQ--VLTIFPDVADRYLSKGIYL----------------------------------------------------------------------------------------------------------------------------------------------------------
123 Fugue 75.2437% -58 - C3 -3PC3 ? A:[12-515] YERPADFIDPGKPSKCKWHLGTAEKSPHIHRGIAHRQQITPNILEVIGCTPLVKLN-N-IPAS-DGI----E-CEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLK---P--G-YTI-IEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTE---AAYDSPEGL---IYVAQQLQRET-PNSI-VL-D-QYRNAGNPLAHYDGTAAEILWQLDN-KVDMIVVSAGTAGTISGIGRKIKEQV--PSCQIV--GVDP-YGS-----I------LARPAELNKT-----D------VQFYEVEGIGYDFPPTVFDDTV---VDVWT---K---IGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALE-HARK-L-K-K--GQR--CVVILPDGIRNYMTK-FVSDNWMEARNFKEPVNEHGHWWWSLAIAELELPAPPVILKSDATVGEAIALMKKHRVDQLPVVDQDDGSVLGVVGQETLITQIVSMNRQQSDPAIKALNKRVIRLNESEILGKLARVLEVDPSVLILGKNPAGKVELKALATKLDVTTFIAAGKQK
50 PsiBlast_CBE 74.9845% -73 - C3 -2ISQ CYSK1_ARATH A:[30-306] ---------------------------------------------------------------------------VAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKP--G--E-SVL-IEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA---KGM---KGA---IAKAEEILAKT-PNGY-ML-Q-QFENPANPKIHYETTGPEIWKGTGG-KIDGFVSGIGTGGTITGAGKYLKEQN--ANVKLY--GVEPVESA-----I------L------SGG-----K------PGPHKIQGIGAGFIPSVL-NVDL--IDEVV---Q---VSSDESIDMARQLALKEGLLVGISSGAAAAAAIK-LAQR---P-ENAGKL--FVAIFPSFGERYLSTVLFD----------------------------------------------------------------------------------------------------------------------------------------------------------
105 HHSearch 74.9743% -61 * C3 *1Z7W CYSK1_ARATH A:[5-309] --------------------------------------IAKDVTELIGNTPLVYLN-N-V--A-EGC----V-GRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK---P--GESVL-IEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG-MK-----GA---IAKAEEILAKT-PNGY-ML-Q-QFENPANPKIHYETTGPEIWKGTGG-KIDGFVSGIGTGGTITGAGKYLKEQN--ANVKLY--GVEP-VESA----I------L------SGG-----K------PGPHKIQGIGAGFIPSVLNVDL---IDEVV---Q---VSSDESIDMARQLALKEGLLVGISSGAAAAAAIK-LAQR-PEN-A--GKL--FVAIFPSFGERYLSTVLFD----------------------------------------------------------------------------------------------------------------------------------------------------------
49 PsiBlast_CBE 74.7445% -70 - C3 -1Z7W CYSK1_ARATH A:[32-308] ---------------------------------------------------------------------------VAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKP--G--E-SVL-IEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA---KGM---KGA---IAKAEEILAKT-PNGY-ML-Q-QFENPANPKIHYETTGPEIWKGTGG-KIDGFVSGIGTGGTITGAGKYLKEQN--ANVKLY--GVEPVESA-----I------L------SGG-----K------PGPHKIQGIGAGFIPSVL-NVDL--IDEVV---Q---VSSDESIDMARQLALKEGLLVGISSGAAAAAAIK-LAQR---P-ENAGKL--FVAIFPSFGERYLSTVLFD----------------------------------------------------------------------------------------------------------------------------------------------------------
23 PsiBlast_CBE 74.3540% -65 - C3 -1M54 CBS_HUMAN E:[33-341] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPT----DSP---ESH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
40 PsiBlast_CBE 74.2640% -63 - C3 -1JBQ CBS_HUMAN C:[98-406] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPT----------ESH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
16 PsiBlast_PDB 74.2341% -61 - C3 -4LMA ? A:[16-316] --------------------------------------------ELVGRTPLVQLN-R-IPQA-EGC----L-GRIVMKLEGMNPAASVKDRIGTHMINSAEKAGLINP--E--T-TVL-VEPTSGNTGIALAMTAAAKGYRLILTMPETMSLERRAMLKAYGATLELTPGS---QGM---KGA---ILRAQQIVDSI-PGAY-ML-Q-QFRNPSNPEIHRLTTAEEIWQDTEG-QVDFIVAGVGTGGTITGVAEVIKSRK--PSFQVV--AVEP-FNSP----V------I------SGG-----N------PGPHKIQGIGAGFIPEVLRTDL---IDEVI---T---VSDEEAFQFGRRLAKEEGLLSGISSGANLCAAIQ-LAQR-P-ENE--GKL--IVVIQPSFGERYLSTLMFQ----------------------------------------------------------------------------------------------------------------------------------------------------------
9 PsiBlast_PDB 74.0840% -63 - C3 -1JBQ CBS_HUMAN A:[98-406] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPT----------ESH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
39 PsiBlast_CBE 73.9540% -63 - C3 -1JBQ CBS_HUMAN D:[98-406] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPT----------ESH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
30 PsiBlast_CBE 73.9540% -58 - C3 -4COO CBS_HUMAN B:[98-406] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSP---ESH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
38 PsiBlast_CBE 73.8640% -63 - C3 -1JBQ CBS_HUMAN E:[98-406] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPT----------ESH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
57 PsiBlast_CBE 73.8140% -66 - C3 -3VBE ? A:[33-328] ----------------------------------------------IGRTPLVYLN-K-VTEG-CGA----Y-VAV--KQEMMQPTASIKDRPAYAMITDAEEKNLITP--G--K-TTL-IEPTSGNMGISMAFMAAMKGYKMVLTMPSYTSLERRVTMRAFGAELILTDPA---KGM---GGT---VKKAYELLENT-PNAH-ML-Q-QFSNPANTQVHFETTGPEIWEDTNG-QVDIFVMGIGSGGTVSGVGQYLKSKN--PNVKIY--GVEPSESN-----V------L------NGG-----K------PGPHHITGNGVGFKPDI---LD---LDVME---KVLEVSSEDAVNMARVLALKEGLMVGISSGANTVAALR-LAQ--L-P-ENKGKL--IVTVHPSFGERYLSSVLFQ----------------------------------------------------------------------------------------------------------------------------------------------------------
41 PsiBlast_CBE 73.8140% -63 - C3 -1JBQ CBS_HUMAN B:[98-406] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPT----------ESH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
26 PsiBlast_CBE 73.7840% -69 - C3 -1M54 CBS_HUMAN B:[33-341] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPT-----------SH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
22 PsiBlast_CBE 73.7140% -70 - C3 -1M54 CBS_HUMAN F:[33-341] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRT------------ESH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
56 PsiBlast_CBE 73.5340% -64 - C3 -3VBE ? B:[33-328] ----------------------------------------------IGRTPLVYLN-K-VTEG-CGA----Y-VAV--KQEMMQPTASIKDRPAYAMITDAEEKNLITP--G--K-TTL-IEPTSGNMGISMAFMAAMKGYKMVLTMPSYTSLERRVTMRAFGAELILTDPA---KGM---GGT---VKKAYELLENT-PNAH-ML-Q-QFSNPANTQVHFETTGPEIWEDTNG-QVDIFVMGIGSGGTVSGVGQYLKSKN--PNVKIY--GVEPSESN-----V------L------NGG-----K------PGPHHITGNGVGFKPDI---LD---LDVME---KVLEVSSEDAVNMARVLALKEGLMVGISSGANTVAALR-LAQ--L-P-ENKGKL--IVTVHPSFGERYLSSVLFQ----------------------------------------------------------------------------------------------------------------------------------------------------------
37 PsiBlast_CBE 73.3940% -61 - C3 -1JBQ CBS_HUMAN F:[98-406] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPT----------ESH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
51 PsiBlast_CBE 73.3845% -70 - C3 -1Z7Y CYSK1_ARATH A:[32-308] ---------------------------------------------------------------------------VAAKLEMMEPCSSVADRIGFSMISDAEKKGLIKP--G--E-SVL-IEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA---KGM---KGA---IAKAEEILAKT-PNGY-ML-Q-QFENPANPKIHYETTGPEIWKGTGG-KIDGFVSGIGTGGTITGAGKYLKEQN--ANVKLY--GVEPVESA-----I------L------SGG-----K------PGPHKIQGIGAGFIPSVL-NVDL--IDEVV---Q---VSSDESIDMARQLALKEGLLVGISSGAAAAAAIK-LAQR---P-ENAGKL--FVAIFPSFGERYLSTVLFD----------------------------------------------------------------------------------------------------------------------------------------------------------
62 PsiBlast_CBE 73.3540% -61 - C3 -3VC3 ? E:[33-328] ----------------------------------------------IGRTPLVYLN-K-VTEG-CGA----Y-VAV--KQEMMQPTASIADRPAYAMITDAEEKNLITP--G--K-TTL-IEPTSGNMGISMAFMAAMKGYKMVLTMPSYTSLERRVTMRAFGAELILTDPA---KGM---GGT---VKKAYELLENT-PNAH-ML-Q-QFSNPANTQVHFETTGPEIWEDTNG-QVDIFVMGIGSGGTVSGVGQYLKSKN--PNVKIY--GVEPSESN-----V------L------NGG-----K------PGPHHITGNGVGFKPDI---LD---LDVME---KVLEVSSEDAVNMARVLALKEGLMVGISSGANTVAALR-LAQ--L-P-ENKGKL--IVTVHPSFGERYLSSVLFQ----------------------------------------------------------------------------------------------------------------------------------------------------------
27 PsiBlast_CBE 73.2940% -60 - C3 -4L0D CBS_HUMAN B:[76-384] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSP---ESH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
6 PsiBlast_PDB 73.2840% -56 - C3 -4COO CBS_HUMAN A:[98-406] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSP---ESH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
112 HHSearch 73.2437% -57 - C3 -3PC3 ? A:[51-362] ---------------------------------------TPNILEVIGCTPLVKLN-N-I--P-ASDGI--E-CEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLK---P--G-YTI-IEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAA-YD-----SPEGLIYVAQQLQRET-PNSI-VL-D-QYRNAGNPLAHYDGTAAEILWQLDN-KVDMIVVSAGTAGTISGIGRKIKEQV--PSCQIV--GVDP-YGSI----L------A------RPAELNKTD------VQFYEVEGIGYDFPPTVFDDTV---VDVWT---K---IGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALE-HARK-L-K-K--GQR--CVVILPDGIRNYMTKFVSD----------------------------------------------------------------------------------------------------------------------------------------------------------
54 PsiBlast_CBE 73.1840% -66 - C3 -3VBE ? D:[33-328] ----------------------------------------------IGRTPLVYLN-K-VTEG-CGA----Y-VAV--KQEMMQPTASIKDRPAYAMITDAEEKNLITP--G--K-TTL-IEPTSGNMGISMAFMAAMKGYKMVLTMPSYTSLERRVTMRAFGAELILTDPA---KGM---GGT---VKKAYELLENT-PNAH-ML-Q-QFSNPANTQVHFETTGPEIWEDTNG-QVDIFVMGIGSGGTVSGVGQYLKSKN--PNVKIY--GVEPSESN-----V------L------NGG-----K------PGPHHITGNGVGFKPDI---LD---LDVME---KVLEVSSEDAVNMARVLALKEGLMVGISSGANTVAALR-LAQ--L-P-ENKGKL--IVTVHPSFGERYLSSVLFQ----------------------------------------------------------------------------------------------------------------------------------------------------------
2 PsiBlast_PDB 73.1740% -62 - C3 -4PCU CBS_HUMAN A:[76-384] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTP--ARFDSP---SSH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
21 PsiBlast_CBE 72.9740% -61 - C3 -4PCU CBS_HUMAN B:[76-384] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSP---SSH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 72.9140% -57 - C3 -4L0D CBS_HUMAN A:[76-384] --------------------------------------ILPDILKKIGDTPMVRIN-K-IGKK-FGL----K-CELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLK---P--G-DTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSP---ESH---VGVAWRLKNEI-PNSH-IL-D-QYRNASNPLAHYDTTADEILQQCDG-KLDMLVASVGTGGTITGIARKLKEKC--PGCRII--GVDP-EGS-----ILAEPEEL------NQT-----E------QTTYEVEGIGYDFIPTVLDRTV---VDKWF---K---SNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK-AAQE-L-Q-E--GQR--CVVILPDSVRNYMTKFLSD----------------------------------------------------------------------------------------------------------------------------------------------------------
60 PsiBlast_CBE 72.8837% -61 - C3 -3PC2 ? A:[56-358] --------------------------------------------EVIGCTPLVKLN-N-IPAS-DGI----E-CEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLK---P--G-YTI-IEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSP---EGL---IYVAQQLQRET-PNSI-VL-D-QYRNAGNPLAHYDGTAAEILWQLDN-KVDMIVVSAGTAGTISGIGRKIKEQV--PSCQIV--GVDP-YGS-----ILARPAEL------NKT-----D------VQFYEVEGIGYDFPPTVFDDTV---VDVWT---K---IGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALE-HARK-L-K-K--GQR--CVVILPDGIRNYMTKFVSD----------------------------------------------------------------------------------------------------------------------------------------------------------
59 PsiBlast_CBE 72.7237% -56 - C3 -3PC3 ? A:[56-358] --------------------------------------------EVIGCTPLVKLN-N-IPAS-DGI----E-CEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLK---P--G-YTI-IEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSP---EGL---IYVAQQLQRET-PNSI-VL-D-QYRNAGNPLAHYDGTAAEILWQLDN-KVDMIVVSAGTAGTISGIGRKIKEQV--PSCQIV--GVDP-YGS-----ILARPAEL------NKT-----D------VQFYEVEGIGYDFPPTVFDDTV---VDVWT---K---IGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALE-HARK-L-K-K--GQR--CVVILPDGIRNYMTKFVSD----------------------------------------------------------------------------------------------------------------------------------------------------------
47 PsiBlast_CBE 72.7141% -57 - C3 -4LMA ? B:[16-316] --------------------------------------------ELVGRTPLVQLN-R-IPQA-EGC----L-GRIVMKLEGMNPAASVKDRIGTHMINSAEKAGLINP--E--T-TVL-VEPTSGNTGIALAMTAAAKGYRLILTMPETMSLERRAMLKAYGATLELTPGS---QGM---KGA---ILRAQQIVDSI-PGAY-ML-Q-QFRNPSNPEIHRLTTAEEIWQDTEG-QVDFIVAGVGTGGTITGVAEVIKSRK--PSFQVV--AVEP-FNSP----V------I------SGG-----N------PGPHKIQGIGAGFIPEVLRTDL---IDEVI---T---VSDEEAFQFGRRLAKEEGLLSGISSGANLCAAIQ-LAQR-P-ENE--GKL--IVVIQPSFGERYLSTLMFQ----------------------------------------------------------------------------------------------------------------------------------------------------------
55 PsiBlast_CBE 72.6840% -65 - C3 -3VBE ? C:[33-328] ----------------------------------------------IGRTPLVYLN-K-VTEG-CGA----Y-VAV--KQEMMQPTASIKDRPAYAMITDAEEKNLITP--G--K-TTL-IEPTSGNMGISMAFMAAMKGYKMVLTMPSYTSLERRVTMRAFGAELILTDPA---KGM---GGT---VKKAYELLENT-PNAH-ML-Q-QFSNPANTQVHFETTGPEIWEDTNG-QVDIFVMGIGSGGTVSGVGQYLKSKN--PNVKIY--GVEPSESN-----V------L------NGG-----K------PGPHHITGNGVGFKPDI---LD---LDVME---KVLEVSSEDAVNMARVLALKEGLMVGISSGANTVAALR-LAQ--L-P-ENKGKL--IVTVHPSFGERYLSSVLFQ----------------------------------------------------------------------------------------------------------------------------------------------------------
58 PsiBlast_CBE 72.3337% -57 - C3 -3PC4 ? A:[56-358] --------------------------------------------EVIGCTPLVKLN-N-IPAS-DGI----E-CEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLK---P--G-YTI-IEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSP---EGL---IYVAQQLQRET-PNSI-VL-D-QYRNAGNPLAHYDGTAAEILWQLDN-KVDMIVVSAGTAGTISGIGRKIKEQV--PSCQIV--GVDP-YGS-----ILARPAEL------NKT-----D------VQFYEVEGIGYDFPPTVFDDTV---VDVWT---K---IGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALE-HARK-L-K-K--GQR--CVVILPDGIRNYMTKFVSD----------------------------------------------------------------------------------------------------------------------------------------------------------
12 PsiBlast_PDB 71.8442% -60 - C3 -2Q3D CYSK_MYCTU A:[14-309] ----------------------------------------------IGRTPLVRLR-RVTDGA-V--------ADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIK---P--D-TII-LEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGA---DGM---SGA---IAKAEELAKTD-QRYF-VP-Q-QFENPANPAIHRVTTAEEVWRDTDG-KVDIVVAGVGTGGTITGVAQVIKERK--PSARFV--AVEP-AASP----V------L------SGG-----Q------KGPHPIQGIGAGFVPPVLDQDL---VDEII---T---VGNEDALNVARRLAREEGLLVGISSGAATVAAL--QVAR-R-P-ENAGKL--IVVVLPDFGERYLSTPLFA----------------------------------------------------------------------------------------------------------------------------------------------------------
84 PsiBlast_CBE 71.6336% -68 - C3 -2PQM ? B:[19-319] --------------------------------------------ETIGGTPLVELHGV-TEHPRIKK----G-TRILVKLEYFNPMSSVKDRVGFNIVYQAIKDGRLK---P--G-MEI-IESTSGNTGIALCQAGAVFGYRVNIAMPSTMSVERQMIMKAFGAELILTEGK---KGM---PGA---IEEVNKMIKEN-PGKYFVA-N-QFGNPDNTAAHHYT-ANEIWEDTDG-EVDIVVSAVGTSGTVIGVAEKLKEKK--KGIKII--AVEP-EESA----V------L------EGK-----A------KGPHGIQGIGAGFIPDIYKKEF---VDEII---P---IKTQDAWKMARAVVKYDGIMCGMSSGAAILAGLK-EAEKPE-N-E--GKT--IVIIVPSCGERYLSTDLYK----------------------------------------------------------------------------------------------------------------------------------------------------------