@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0154: (2015-12-12 )
MPLETITLAHIYEEQGFFEEALQIYTNILKKTPDNTEALKQMKRLEKIQKNCAPFKHDALLKQHYLNFIKGDRLSVENLEKWLVEWN
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20........30--.--......-----------------------------.--------------.40........50........60......-..-70------.....-....80......-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MP
L
E
T
I
T
L
A
H
I
Y
E
EQ
G
F
F
E
E
A
L
Q
I
Y
T
N
I
L
K---K--TPD
N
T
E
-----------------------------
A
--------------
L
K
Q
M
K
R
L
E
K
I
Q
K
NCAPF
K
H
D
A
L
L
K
Q
H
Y
L
N
-
F
I-K-------GDRL
S
-
V
E
N
L
E
K
W
L
VEWN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
70.31
34%
-69
- C2 -
1JPL
1
GGA3_HUMAN
A:
[46-112]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
P
Q
I
A
V
R
L
L
A
H
K
I
Q
--
S
P
Q
E
W
E
-----------------------------
A
--------------
L
Q
A
L
T
V
L
E
A
C
M
K
N
C
G
R
R
F
H
N
E
V
G
K
F
R
F
L
N
E
L
I
-
K
V
V
SPKYL
G
D
R
V
S
-
E
K
V
K
T
K
V
I
E
L
L
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
68.85
34%
-76
- C2 -
1LF8
1
GGA3_HUMAN
B:
[46-112]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
P
Q
I
A
V
R
L
L
A
H
K
I
Q
--
S
P
Q
E
W
E
-----------------------------
A
--------------
L
Q
A
L
T
V
L
E
A
C
M
K
N
C
G
R
R
F
H
N
E
V
G
K
F
R
F
L
N
E
L
I
-
K
V
V
SPKYL
G
D
R
V
S
-
E
K
V
K
T
K
V
I
E
L
L
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
68.46
34%
-70
- C2 -
1LF8
1
GGA3_HUMAN
C:
[46-112]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
P
Q
I
A
V
R
L
L
A
H
K
I
Q
--
S
P
Q
E
W
E
-----------------------------
A
--------------
L
Q
A
L
T
V
L
E
A
C
M
K
N
C
G
R
R
F
H
N
E
V
G
K
F
R
F
L
N
E
L
I
-
K
V
V
SPKYL
G
D
R
V
S
-
E
K
V
K
T
K
V
I
E
L
L
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
67.08
34%
-73
- C2 -
1JUQ
1
GGA3_HUMAN
A:
[46-112]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
P
Q
I
A
V
R
L
L
A
H
K
I
Q
--
S
P
Q
E
W
E
-----------------------------
A
--------------
L
Q
A
L
T
V
L
E
A
C
M
K
N
C
G
R
R
F
H
N
E
V
G
K
F
R
F
L
N
E
L
I
-
K
V
V
SPKYL
G
D
R
V
S
-
E
K
V
K
T
K
V
I
E
L
L
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
Fugue
66.83
22%
-46
- C2 -
4HNY
4
NAT1_YEAST
A:
[54-862]
V
D
S
L
A
L
K
G
L
D
L
Y
S
V
GE
K
D
D
A
A
S
Y
V
A
N
A
I
RAS
P
I
C
C
H
V
L
G
I
Y
M
R
N
T
KE
Y
K
E
S
I
K
W
F
T
A
A
L
N
N
GSTNKQ
I
Y
R
D
L
A
T
L
Q
S
Q
I
GD
F
K
N
A
L
V
S
R
K
K
Y
W
E
A
F
LGY
R
A
N
W
T
S
L
A
V
A
Q
D
V
N
GE
R
Q
Q
A
I
N
T
L
S
Q
F
E
K
L
A
EGKISDSE
K
Y
E
H
S
E
C
L
M
Y
K
N
D
I
M
Y
K
A
A
SDN
Q
D
K
L
Q
N
V
L
K
H
L
N
D
I
EPCVFD
K
F
G
L
L
E
-
R
K
A
T
I
Y
M
K
L
G
Q
L
K
D
A
S
I
V
Y
R
T
L
I
K
---
R
--
N
P
D
N
F
K
-----------------------------
Y
--------------
Y
K
L
L
E
V
S
L
G
I
Q
G
-------
D
N
K
L
K
K
A
L
Y
G
-
K
L
-
E
-------
Q
F
Y
P
R
-
C
E
P
P
K
F
I
P
L
T
F
L
QD
K
E
E
L
S
K
K
L
R
E
Y
V
L
P
Q
L
E
R
GVPA
T
F
S
N
V
K
P
L
Y
Q
R
RKSKV
S
P
L
L
E
K
I
V
L
D
Y
L
S
G
LDPTQD
P
I
P
F
I
W
T
N
Y
Y
L
S
Q
H
F
L
F
L
KD
F
P
K
A
Q
E
Y
I
D
A
A
L
D
H
TPTL
V
E
F
Y
I
L
K
A
R
I
L
K
H
L
GL
M
D
T
A
A
G
I
L
E
E
G
R
Q
L
DLQD
R
F
I
N
C
K
T
V
K
Y
F
L
R
A
NN
I
D
K
A
V
E
V
A
S
L
FTKNDDSVNGIKDLHLVEA
S
W
F
I
V
E
Q
A
E
A
Y
Y
R
L
Y
L
D
R
K
K
K
L
D
D
L
A
SQ
I
A
N
D
I
K
E
N
Q
W
L
V
R
K
Y
K
G
L
A
L
K
R
F
N
A
I
P
K
F
Y
K
Q
F
E
D
D
Q
LDFH
S
Y
C
M
R
K
GT
P
R
A
Y
L
E
M
L
E
W
G
K
A
LYTK
P
M
Y
V
R
A
M
K
E
A
S
K
L
Y
F
Q
M
H
D
D
R
L
K
R
K
S
D
S
L
DENDVFG
E
K
L
I
E
TST
P
M
E
D
F
A
T
E
FY
N
N
Y
S
M
Q
VREDERD
Y
I
L
D
F
E
F
N
Y
R
I
GK
L
A
L
C
F
A
S
L
N
K
F
A
K
R
FGTTS
G
L
F
G
S
M
A
I
V
L
L
H
A
T
RPFDPIL
K
K
V
V
T
K
S
L
EKEYSEFD
W
L
N
F
Y
Q
E
KFGKND
I
N
G
L
L
F
L
Y
R
Y
R
DDVPIG
S
S
N
L
K
E
M
I
I
S
S
L
SPLE
P
H
S
Q
N
E
I
L
Q
Y
YLYPYDVPDY
21
PsiBlast_CBE
66.52
34%
-67
- C2 -
1LF8
1
GGA3_HUMAN
D:
[46-112]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
P
Q
I
A
V
R
L
L
A
HKI
Q
--
S
P
Q
E
W
E
-----------------------------
A
--------------
L
Q
A
L
T
V
L
E
A
C
M
K
N
C
G
R
R
F
H
N
E
V
G
K
F
R
F
L
N
E
L
I
-
K
VVSPKYL
G
D
R
V
S
-
E
K
V
K
T
K
V
I
E
L
L
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
66.22
34%
-68
- C2 -
1LF8
1
GGA3_HUMAN
A:
[46-112]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
P
Q
I
A
V
R
L
L
A
H
K
I
Q
--
S
P
Q
E
W
E
-----------------------------
A
--------------
L
Q
A
L
T
V
L
E
A
C
M
K
N
C
G
R
R
F
H
N
E
V
G
K
F
R
F
L
N
E
L
I
-
K
V
V
SPKYL
G
D
R
V
S
-
E
K
V
K
T
K
V
I
E
L
L
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
Fugue
58.35
14%
-19
- C2 -
1YA0
1
SMG7_HUMAN
A:
[1-497]
--------------------------------------------------------------M
S
L
Q
S
A
Q
Y
L
R
Q
A
E
V
L
K
A
D
M
T
DSKLGPA
E
V
W
T
S
R
Q
A
L
Q
D
L
Y
Q
K
M
L
V
T
D
L
E
Y
A
L
D
K
K
V
E
Q
D
L
W
N
HAF
K
N
Q
I
T
T
L
Q
G
Q
A
KNRANPN
R
S
E
V
Q
A
N
L
S
L
F
L
E
A
A
S
G
F
Y
T
Q
L
L
Q
E
L
C
TQS
S
S
C
S
Y
I
C
Q
H
C
L
V
H
L
G
D
I
A
R
Y
R
N
Q
T
S
Q
A
E
S
Y
Y
R
H
A
A
Q
---
L
--
V
P
S
N
G
Q
-----------------------------
P
--------------
Y
N
Q
L
A
I
L
A
S
S
K
G
D
---
H
L
T
T
I
F
Y
Y
C
R
S
I
A
-
V
K
-
F
-------
P
F
P
A
A
-
S
T
N
L
Q
K
A
L
S
K
A
L
ESRDEVKTKWG
V
S
D
F
I
K
A
F
I
K
F
H
G
H
V
Y
L
SKSLEK
L
S
P
L
R
E
K
L
E
E
Q
F
K
E
L
L
F
Q
KAFN
S
Q
Q
L
V
H
V
T
V
I
N
L
F
Q
L
H
H
L
RDFSNE
T
E
Q
H
T
Y
S
Q
D
E
Q
L
C
W
T
Q
L
L
A
L
F
M
S
F
L
G
I
L
C
K
CPLQNSQEESYNAYP
L
P
A
V
K
V
S
M
D
W
L
R
L
R
PRVFQE
A
V
V
D
E
R
Q
Y
I
W
P
W
L
I
S
L
L
N
S
FHPHEEDLSISATPL
P
E
E
F
E
L
QGFLALRPSFRNLDFSKGHK
E
G
Q
Q
R
R
I
R
Q
Q
R
L
I
S
I
G
K
W
I
A
D
N
QPRLIQCENEVG
K
L
L
F
I
T
EIPELILEDP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
HHSearch
58.18
16%
-33
- C2 -
3UPV
1
A:
[8-100]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
E
G
K
E
Y
F
T
K
S
D
W
P
N
A
V
K
A
Y
T
E
M
I
K
---
R
--
A
P
E
D
A
R
-----------------------------
G
Y
S
N
R
A
A
A
L
A
K
L
MS
F
P
E
A
I
A
D
C
N
K
A
I
E
K
D
P
N
-
F
V
R
A
Y
-
I
R
K
A
T
A
-
Q
I
A
V
-------
K
E
Y
A
S
A
L
E
T
L
D
A
A
R
T
K
D
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
HHSearch
56.78
22%
-50
- C2 -
2Y4T
-
DNJC3_HUMAN
A:
[109-216]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
R
G
H
L
L
L
K
Q
G
K
L
D
E
A
E
D
D
F
K
K
V
L
K
---
S
--
N
P
S
E
N
E
E
K
E
A
Q
S
Q
L
I
K
S
D
E
M
Q
R
L
R
S
Q
A
L
N
A
F
G
S
GD
Y
--------------
T
A
A
I
A
F
L
D
K
I
L
E
V
C
V
W
-
D
A
E
L
R
-
E
L
R
A
E
C
-
F
I
K
E
-------
G
E
P
R
K
A
I
S
D
L
K
A
A
S
K
L
K
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
HHSearch
56.76
19%
-40
- C2 -
2Y4T
-
DNJC3_HUMAN
A:
[40-133]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
E
L
G
K
K
L
L
A
A
G
Q
L
A
D
A
L
S
Q
F
H
A
A
V
D
---
G
--
D
P
D
N
Y
I
-----------------------------
A
Y
Y
R
R
A
T
V
F
L
A
M
GK
S
K
A
A
L
P
D
L
T
K
V
I
Q
L
K
M
D
-
F
T
A
A
R
-
L
Q
R
G
H
L
-
L
L
K
Q
-------
G
K
L
D
E
A
E
D
D
F
K
K
V
L
K
S
N
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
56.75
15%
-48
- C2 -
3AS5
1
?
A:
[47-137]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
G
I
A
Y
V
K
T
G
A
V
D
R
G
T
E
L
L
E
R
S
L
A
---
D
--
A
P
D
N
V
K
-----------------------------
V
A
T
V
L
G
L
T
Y
V
Q
V
QK
Y
D
L
A
V
P
L
L
I
K
V
A
E
A
N
P
I
-
N
F
N
V
R
-
F
R
L
G
V
A
-
L
D
N
L
-------
G
R
F
D
E
A
I
D
S
F
K
I
A
L
G
L
R
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
HHSearch
56.34
18%
-24
- C2 -
3VTX
-
?
A:
[10-98]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
G
D
K
K
R
T
K
G
D
F
D
G
A
I
R
A
Y
K
K
V
L
K
---
A
--
D
P
N
N
V
E
-----------------------------
T
L
L
K
L
G
K
T
Y
M
D
I
GL
P
N
D
A
I
E
S
L
K
K
F
V
V
L
D
T
T
-
S
A
E
A
Y
-
Y
I
L
G
S
A
-
N
F
M
I
-------
D
E
K
Q
A
A
I
D
A
L
Q
R
A
I
A
L
N
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
Fugue
56.15
17%
-32
- C2 -
1FCH
2
PEX5_HUMAN
A:
[46-246]
----------------------------------------------------------------------------------------------------------------------------------SATYDKGYQFEEENPLRDHPQ
P
F
E
E
G
L
R
R
L
Q
E
GD
L
P
N
A
V
L
L
F
E
A
A
V
Q
Q
D
PK
H
M
E
A
W
Q
Y
L
G
T
T
Q
A
E
N
E
Q
E
L
L
A
I
S
A
L
R
R
C
L
E
---
L
--
K
P
-----------------------------------------------------------
D
N
Q
T
A
L
M
A
L
A
V
S
F
T
N
-----
E
-
S
-------
L
Q
R
Q
A
-
C
E
I
L
R
D
W
L
R
Y
T
P
AYAHLVTRIL
G
S
L
L
S
D
S
L
F
L
E
V
K
E
L
F
L
A
A
V
R
L
DPTSID
P
D
V
Q
C
G
L
G
V
L
F
N
L
S
GE
Y
D
K
A
V
D
C
F
T
A
A
L
S
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
55.18
16%
-23
- C2 -
3UQ3
1
A:
[144-235]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
G
K
E
Y
F
T
K
S
D
W
P
N
A
V
K
A
Y
T
E
M
I
K
---
R
--
A
P
E
D
A
R
-----------------------------
G
Y
S
N
R
A
A
A
L
A
K
L
MS
F
P
E
A
I
A
D
C
N
K
A
I
E
K
D
P
N
-
F
V
R
A
Y
-
I
R
K
A
T
A
-
Q
I
A
V
-------
K
E
Y
A
S
A
L
E
T
L
D
A
A
R
T
K
D
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
55.10
10%
-34
- C2 -
3AS5
1
?
A:
[82-170]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
L
T
Y
V
Q
V
Q
K
Y
D
L
A
V
P
L
L
I
K
V
A
E
---
A
--
N
P
I
N
F
N
-----------------------------
V
R
F
R
L
G
V
A
L
D
N
L
GR
F
D
E
A
I
D
S
F
K
I
A
L
G
L
R
P
N
-
E
G
K
V
H
-
R
A
I
A
F
S
-
Y
E
Q
M
-------
G
R
H
E
E
A
L
P
H
F
K
K
A
N
E
L
D
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
54.96
24%
-52
- C2 -
2XZE
2
STABP_HUMAN
A:
[41-119]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
I
I
R
M
A
S
I
Y
S
E
E
G
N
I
E
H
A
F
I
L
Y
N
K
Y
I
-----------
T
L
-----------------------------
F
--------------
I
E
K
L
P
K
H
R
D
Y
K
S
A
V
I
P
E
K
K
D
T
V
K
K
L
K
E
I
A
-
F
P
-
K
-------
A
E
E
L
K
-
A
E
L
L
K
R
Y
T
K
E
Y
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
53.95
12%
-31
- C2 -
3GYZ
4
IPGC_SHIFL
A:
[41-132]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Y
A
Y
D
F
Y
N
K
G
R
I
E
E
A
E
V
F
F
R
F
L
C
I
---
Y
--
D
F
Y
N
V
D
-----------------------------
Y
I
M
G
L
A
A
I
Y
Q
I
K
EQ
F
Q
Q
A
A
D
L
Y
A
V
A
F
A
L
G
K
N
-
D
Y
T
P
V
-
F
H
T
G
Q
C
-
Q
L
R
L
-------
K
A
P
L
K
A
K
E
C
F
E
L
V
I
Q
H
S
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
53.88
30%
-62
- C2 -
1NA3
2
?
A:
[48-90]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
---
L
--
D
P
N
N
A
E
-----------------------------
A
--------------
K
Q
N
L
G
N
A
K
Q
K
Q
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64
Fugue
53.80
26%
-39
- C2 -
4MBQ
-
?
A:
[16-64]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D
E
A
A
T
K
L
D
L
A
R
A
Y
I
D
M
G
D
S
E
G
A
R
D
I
L
D
E
V
L
A
---
E
GN
D
S
Q
Q
A
E
-----------------------------
A
--------------
R
E
L
L
E
R
L
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------