@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0159: (2015-12-12 )
MLDFIQELSTPHVRDFFLLFLRVSGVLSFFPFFENHLVPLSVRGALSLYVSAIFYPTLEFSNAIYTPEGFIIACLCELFLGVCASVFLQIVFASLVFATDSISFSMGLTMASAYDPISGSQKPIVGQALLLLAILILLDLSFHHQIILFVDHSLKAVPLGRFVFEPELAKNIVKAFSHLFVIGFSMAFPILCLVLLSDIIFGMIMKTHPQFNLLAIGFPVKIAIGFVGIILIASAIMGRFKEEISLAFSVISKIF
Atome Classification :
(18 SA)
---------------------------------------.........10.....----------------...--20......-----------..30........40-...----.---.....50........60----........--.70..-------------------------------......80..----......90----------.....---...100..---..--.----------------..110.----......120---------.......130......-----.140--------.----.....-----...150.---...----...160-....-----....170-------------........180--........--------------190......------.200..----------------..---..-----.210....-----------...220-----------......-----------..230-.....---..240..-----------.....250-----...--------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------
M
L
D
F
I
Q
E
LST
P
H
V
R
D
F
----------------
F
L
L
--
F
L
R
V
S
G
V
L
-----------
S
F
F
P
F
F
ENH
L
V
P
L
--
S
V
R
----
G
---
A
L
S
L
Y
V
S
A
I
F
YPTLEF-----SNAIYTPE--
G
F
I
I
A
-------------------------------
C
L
C
E
L
F
L
G
V
C
----
A
S
V
F
L
Q
I
V
----------
F
A
S
L
V
---
F
ATDS
I
S
F
---SM--G----------------
L
T
M
ASA----YDPISGSQK---------P
I
V
G
Q
A
L
L
L
L
A
I
L
I
L
L-----DL----------S----FH
H
Q
I
-----
I
L
F
V
DHS---LKA----VPLG
R
--
F
V
F
E
-----
P
E
L
A
K
N
--------------
I
V
K
A
F
S
H
L
F
-
V
--
I
G
F
S
M
A
F
P
--------------
I
L
C
L
V
L
L
S
D
------
I
I
F
G
M
I
----------------
M
K---TH-----PQ
F
N
L
L
A
I-----------GF
P
V
K
------------
I
A
I
G
F
V
-----------
G
I
I
L
I
-
A
S
A
I
M
---
G
R
F
K
E
E
I
-----------
S
L
A
F
S
V
I
S
-----
K
IF--------------------------
13
Fugue
90.06
17%
-189
* C7 *
4V1S
2
?
A:
[37-395]
----------------------PGVEIGNND
Y
Y
T
W
C
K
E
T
L
S
V
I
D
K
D
L
K
I
S
G
T
H
S
Y
YENQDRSQVSFI
W
G
N
I
F
L
L
--
Y
T
Y
T
E
G
I
S
L
SKSEW
S
D
A
L
M
N
C
F
L
N
F
D
N
Y
W
H
P
N
YK
G
I
A
----
G
---
Y
A
T
L
P
T
S
A
E
K
V
P
D
R
----------
F
Y
D
E
N
--
G
W
T
A
I
-------------------------------
G
L
C
D
A
Y
L
A
T
Q
----
N
N
S
Y
L
E
K
A
----------
K
G
A
L
A
---
F
S
L
S
G
E
D
N
---
V
L
G
G
G
----------------
I
Y
F
Q
E
T
----
F
V
S
L
P
-
V
Q
K
---------
N
T
I
C
S
A
V
T
M
L
S
C
M
K
L
Y
-----
E
I
----------
T
QDR
Q
Y
L
D
A
A
-----
I
R
I
N
D
W
T
---
V
E
N
----
L
L
D
K
S
DN
L
L
W
D
-----
A
K
M
V
A
D
GSVNTQKW
S
Y
N
A
G
F
M
I
R
S
W
L
K
M
Y
-
Q
--
A
T
K
D
E
K
Y
L
--------------
S
Q
A
K
A
T
L
A
S
------
S
E
A
K
W
Y
----------------
N
S
---
I
N
GALND
P
G
Y
F
A
F
S
I
I
D
S
W
F
D
M
Y
D
T
D
K
N
T
V
W
------------
L
T
K
A
F
H
-----------
A
I
N
F
I
-
H
N
K
L
R
DGN
G
R
Y
P
E
H
W
GTPTTSNLEKY
D
L
R
F
S
T
V
A
-----
A
Y
M
Y
M
R
A
A
N
Y
K
R
I
L
N--------------
22
Fugue
80.11
21%
-155
- C7 -
4CR2
-
PSA5_YEAST (first)
S:
[126-478]
----------K
T
I
E
V
T
A
E
I
N
C
F
M
H
L
L
V
Q
L
F
L
WDSKELEQ
L
V
E
F
N
R
K
V
V
I
P
N
L
L
C
Y
----------------
Y
N
L
RS
L
N
L
I
N
A
K
L
-----------
W
F
Y
I
Y
L
S
H
E
T
L
A
R
--
S
S
E
EINS
D
---
N
Q
N
I
I
L
R
S
T
M
M
K
F
L
K
I
-----
A
S
L
K
H
D
N
E
T
K
A
M
L
I
N
-------------------------------
L
I
L
R
D
F
L
N
N
G
EVDS
A
S
D
F
I
S
K
L
EYPHTDVS
S
S
L
E
A
R
Y
---
F
F
Y
L
S
K
I
N
---
A
I
--
Q
----------------
L
D
Y
S
T
A
----
N
E
Y
I
I
A
A
I
R
KAPH
N
S
K
S
L
G
F
L
Q
Q
S
N
K
L
H
C
C
I
Q
L
L
M
GDIP
E
L
----------
S
----
F
F
H
Q
S
NM
Q
K
S
L
L
P
Y
Y
H
L
---
T
K
A
----
V
K
L
G
D
-----
L
-----
K
K
F
T
S
T
--------------
I
T
K
Y
K
Q
L
L
L
-
K
--
D
D
T
Y
Q
------------------
L
C
V
R
L
R
S
N
------
V
I
K
T
G
I
----------------
R
I
ISL
T
Y
-----
K
K
I
S
L
R
D
I
-----------
C
L
K
L
N
------------
L
D
S
E
Q
T
-----------
V
E
Y
M
V
-
S
R
A
I
R
D
--
G
V
I
E
A
K
I
-----------
N
H
E
D
G
F
I
E
T
T
ELL
N
I
Y
DSE
D
P
Q
Q
V
F
D
E
R
I
K
F
A
N
Q
L
H
D
E
Y
L
V
S
19
Fugue
66.78
11%
-173
- C6 -
3TW5
2
?
A:
[1-366]
--------------------------------EANGN
Q
D
I
A
K
L
E
A
Y
F
G
T
K
M
E
M
T
L
----------------
K
D
L
--
P
T
V
G
V
H
T
P
S
P
W
A
G
------
P
Y
W
P
T
Y
Q
D
S
I
N
V
Q
--
W
S
Q
----
G
QPS
A
A
E
K
Y
A
K
A
F
G
K
D
V
K
T
F
-----
M
D
A
V
S
K
K
N
--
G
I
D
S
Q
SGRKKCSSDDDCSTLTDGS
S
C
S
I
R
TGKT
S
G
Y
C
I
P
T
-
W
F
G
I
S
----
H
A
W
S
P
A
A
I
----------
L
E
T
E
P
K
C
P
V
K
H
N
G
V
T
F
Q
P
M
D
L
--
K
----------------
A
L
V
S
L
V
----
Y
D
G
-
A
R
V
Q
T
---------
V
F
T
G
D
L
N
P
A
Y
F
H
I
A
S
A
-----
N
I
----------
L
----
G
K
L
N
S
-----
T
F
V
A
D
V
T
---
A
G
A
E
V
W
N
Q
P
V
R
G
--
F
K
V
Y
-----
E
Q
T
E
M
T
--------------
L
E
E
G
A
Q
T
F
Y
G
L
--
E
A
Y
P
W
N
A
A
--------------
A
K
S
L
V
Y
V
K
S
------
R
L
S
W
I
Y
E
T
YTDGGLVSSGQIDK
F
T
---
T
G
-----
Q
Y
Y
Y
Y
L
L
E
-----------
L
D
D
A
G
------------
E
I
I
G
G
E
W
V
YGSDDDHPD
F
L
W
L
P
-
K
A
K
P
A
---
A
N
T
V
T
S
V
-----------
G
L
S
Y
A
D
V
S
-----
M
L
L
K
K
S
A
A
CT-------------------
21
Fugue
66.40
7%
-153
- C5 -
1A4M
2
ADA_MOUSE
A:
[1-349]
TPAFN
K
P
K
V
E
LHVHLDGAIK
P
E
T
I
L
Y
F
G
K
K
R
GIALPADT
V
E
E
L
R
N
I
I
G
M
D
K
P
L
S
L
----------------
P
G
F
--
L
A
K
F
D
Y
Y
M
-----------
P
V
I
A
G
C
R
E
A
I
K
R
I
--
A
Y
E
----
F
---
V
E
M
K
A
K
E
G
V
V
Y
V
E
V
R
Y
-----
S
P
H
L
L
A
N
S
--
K
V
D
P
M
-------------------------------
P
W
N
Q
T
E
G
D
V
T
----
P
D
D
V
V
D
L
V
----------
N
Q
G
L
Q
---
E
G
E
Q
A
F
G
I
---
K
V
--
R
----------------
S
I
L
C
C
M
----
R
H
Q
P
S
W
S
L
E
---------
V
L
E
L
C
K
K
Y
N
Q
K
T
V
V
A
M
-----
D
L
A
G
DETIEGSS
L
----
F
P
G
H
V
-----
E
A
Y
E
G
A
V
---
K
N
G
----
I
H
R
T
V
--
H
A
G
E
-----
V
G
S
P
E
V
--------------
V
R
E
A
V
D
I
L
K
-
T
ER
V
G
H
G
Y
H
T
I
ED
E
A
L
Y
N
R
L
L
K
E
NM
H
F
E
V
C
P
W
S
S
------
Y
L
T
G
A
W
DP--------------
K
T
---
T
H
-----
A
V
V
R
F
K
N
D
-----------
K
A
N
Y
S
------------
L
N
T
D
D
P
-----------
L
I
F
K
S
T
L
D
T
D
Y
---
Q
M
T
K
K
D
M
-----------
G
F
T
E
E
E
F
K
-----
R
L
N
I
N
A
A
K
S
SFLP
E
E
E
K
K
E
L
L
E
R
L
Y
R
E
Y
Q
16
Fugue
60.91
12%
-165
* C6 *
2CH5
4
NAGK_HUMAN
A:
[1-347]
---PQFM
A
A
I
Y
G
G
V
EGGGT
R
S
E
V
L
L
V
S
EDGKIL
A
E
A
D
G
L
S
T
N
H
W
L
I
G
T
D
K
C
V
E
R
I
----------------
N
E
M
--
V
N
R
A
K
R
K
A
-----------
G
V
D
P
L
V
P
L
R
S
L
G
L
--
S
L
S
----
G
---
G
D
Q
E
D
A
G
R
I
L
I
E
E
L
R
D
R
FPYL
S
E
S
Y
L
I
T
T
--
D
A
A
G
S
-------------------------------
I
A
T
A
T
P
D
G
G
V
----
V
L
I
S
G
T
G
S
----------
N
C
R
L
I
---
N
P
D
G
S
E
S
G
---
C
G
--
G
WGHMMGDEGS
A
Y
W
I
A
H
Q
A
V
K
I
V
----
F
D
S
I
D
N
L
E
A
---------
A
P
H
D
I
G
Y
V
K
Q
A
M
F
H
Y
F
-----
Q
V
----------
P
----
D
R
L
G
I
-----
L
T
H
L
Y
R
D
FD
K
C
R
F
----
A
G
F
C
R
--
K
I
A
E
G
A
Q
Q
G
D
P
L
S
R
Y
--------------
I
F
R
K
A
G
E
M
L
-
G
--
R
H
I
V
A
V
L
P
--------------
E
I
D
P
V
L
F
Q
G
KI
G
L
P
I
L
C
V
G
S
V
----------------
W
K
---
S
W
-----
E
L
L
K
E
G
F
L
-----------
L
A
L
T
Q
G
RAQNFFS
S
F
T
L
M
K
L
R
H
S
-----------
S
A
L
G
G
-
A
S
L
G
A
---
R
H
I
G
H
L
L
-----------
P
M
D
Y
S
A
N
A
-----
I
A
F
Y
S
Y
T
FS--------------------
2
PsiBlast_PDB
48.00
28%
-137
- C8 -
3VMK
3
?
A:
[253-323]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
C
----
S
N
L
F
G
D
I
V
----------
S
D
E
I
A
---
M
L
T
G
S
M
G
L
---
L
A
--
S
----------------
I
S
M
N
S
Q
G
F
G
M
Y
E
P
A
G
G
S
A
P
---------
D
I
A
G
Q
G
I
A
N
P
V
A
Q
I
L
--------------------------
S
A
-----
A
L
L
L
R
H
S
---
L
K
L
----
E
D
A
A
L
--
A
I
E
A
-----
A
V
S
K
A
L
--------------
S
D
G
Y
L
T
C
E
L
-
L
--
P
A
S
E
R
S
Q
A
--------------
K
S
T
S
Q
M
G
D
Y
------
I
A
Q
A
I
A
----------------
E
G
-----------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
46.42
28%
-140
- C8 -
3VML
3
A:
[253-323]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
C
----
S
N
L
F
G
D
I
V
----------
S
D
E
I
A
---
M
L
T
G
S
M
G
L
---
L
A
--
S
----------------
I
S
M
N
S
Q
G
F
G
M
Y
E
P
A
G
G
S
A
P
---------
D
I
A
G
Q
G
I
A
N
P
V
A
Q
I
L
--------------------------
S
A
-----
A
L
L
L
R
H
S
---
L
K
L
----
E
D
A
A
L
--
A
I
E
A
-----
A
V
S
K
A
L
--------------
N
S
G
Y
L
T
G
E
L
-
L
--
S
S
D
Q
R
H
K
A
--------------
K
T
T
V
Q
M
G
D
F
------
I
A
D
A
V
K
----------------
A
G
-----------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
30.46
11%
-6
- C8 -
2HWJ
-
?
A:
[62-88]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
Y
-----
L
I
----------
D
----
H
H
H
L
V
-----
L
A
L
S
K
E
G
---
V
E
H
----
V
L
T
S
E
--
V
A
K
F
-----
S
H
L
G
K
D
--------------
E
F
W
S
V
M
D
H
R
-
N
--
L
I
Y
P
F
D
A
Q
--------------
G
L
R
R
Q
S
G
D
I
------
P
K
N
I
H
D
----------------
L
E
---
D
D
-----
P
F
R
S
L
A
G
A
-----------
L
R
M
A
G
------------
G
Y
A
K
V
I
-----------
I
P
F
S
E
-
F
G
W
A
D
---
F
L
R
R
R
I
D
-----------
R
D
L
L
S
D
S
F
-----
D
D
A
--------------------------
11
HHSearch
29.21
8%
75
- C8 -
1XW3
1
SRXN1_HUMAN
A:
[66-91]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Y
-----
S
F
----------
G
----
G
C
H
R
Y
-----
A
A
Y
Q
Q
L
Q
---
R
E
T
----
I
P
A
K
L
--
V
Q
S
T
-----
L
S
D
L
R
V
--------------
Y
L
G
A
S
T
P
D
L
-
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
29.06
27%
119
- C4 -
3WKN
-
?
E:
[23-51]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
A
W
H
---
L
G
--
E
----------------
L
V
W
A
T
Y
----
Y
D
P
E
T
G
T
W
E
---------
P
D
W
Q
R
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
27.48
8%
52
- C8 -
1YZS
-
SRXN1_HUMAN
A:
[93-118]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Y
-----
S
F
----------
G
----
G
C
H
R
Y
-----
A
A
Y
Q
Q
L
Q
---
R
E
T
----
I
P
A
K
L
--
V
Q
S
T
-----
L
S
D
L
R
V
--------------
Y
L
G
A
S
T
P
D
L
-
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
22.52
29%
1356
- C1 -
1SSZ
-
A:
[19-25]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
---
M
L
-----
P
Q
L
V
C
R
L
V
-----------
L
R
C
S
--------------------------------------------------------------------------------------------------------
12
HHSearch
21.80
7%
296
- C8 -
2WW9
-
SC61G_YEAST
B:
[59-72]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
V
G
I
-----
I
G
Y
A
I
K
L
I
----------
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
21.10
27%
777
- C2 -
1LJ2
-
IF4G1_HUMAN
C:
[9-19]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
I
----
R
D
P
N
Q
G
G
K
D
---------
I
T
E
E
I
M
S
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
20.88
5%
73
* C8 *
1V54
-
COX6C_BOVIN
I:
[18-37]
------------------------------------------------------------------------------------------------------------------------------------------------------------
R
-------------------------------
L
R
F
H
I
V
G
A
F
M
----
V
S
L
G
F
A
T
F
----------
Y
K
F
A
V
---
A
E
K
R
K
K
A
Y
---
A
D
--
F
----------------
Y
R
N
Y
D
S
----
M
K
D
F
E
E
M
R
K
---------
A
G
I
F
Q
S
A
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
20.82
13%
183
- C8 -
1Q90
2
M:
[12-27]
------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-------------------------------
M
V
G
M
T
L
V
G
L
A
----
I
G
F
V
L
L
R
V
----------
E
S
L
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
19.35
45%
660
- C3 -
3WKN
-
?
E:
[34-44]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
Y
----
Y
D
P
E
T
G
T
W
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
13.04
14%
429
- C8 -
1QLO
-
ICP47_HHV11
A:
[3-16]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
A
L
E
---
M
A
D
T
F
L
D
N
---
M
R
--
V
----------------
G
P
R
T
Y
A
----
D
V
R
D
E
I
N
K
R
---------
G
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------