@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0182: (2015-12-13 )
MKLSELLSAYSIETEFSNDFEVHALAELDKATPNDISYIDQVCYLKLLKDSKAGAVFIRKKESSKVPKSMQALIVDNPHLAFAKVSHAFKIPFFKNPQSVNEPKHFEKVTIMPNVVIGEGVEIGENSLIYPGVVIADGVKIGKNCILYPRVILYQNTILEDNVIIHAGSVIGGDGFGYAHTALGEHVKIEHVGIVRIQKNVEIGANTAIDRAVFGETLIKEGVKIDNLVQIGHNCVLGEHSIVVSQVGLSGSTTTGRNVVFGGQVGIGGHLHVGEFTQIGGKSAVGKDLPPNTNFAGAIPAMEIHEWHHFLAHLRTNFRKQQKTSLLQKAKGFFKS
Atome Classification :
(20 SA)
-----.........10........20........30........40........50........60.....--...70--....--....80........90.------...-----....100-..----------.-------..-----.--...110.......120.------......130.......140....------------...150.......160.......170.......----------180..---.....190-........200.......210.--......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----M
K
L
S
E
L
L
S
A
Y
SIETEFSNDF
E
V
H
A
L
A
E
L
DKATPN
D
I
S
Y
I
D
Q
V
C
Y
L
K
L
LKDSKA
G
A
V
F
I
RKKESSKV--
P
K
S
M
Q
--
A
LIV--DNP
H
L
A
F
A
KV
S
H
A
F
KIP------FFK-----NPQSV---NE----------P-------KH-----
F
--
E
K
V
T
IMPN
V
V
IGEGVEI------GEN
S
L
I
YP
G
V
V
I
ADGVKIGKN
C
I
------------
L
Y
P
R
V
I
L
Y
QNTILED
N
V
I
I
H
AGSVIGGDGF
G
Y
A
----------
H
TALG---
E
H
V
K
I
E
H
--
V
G
I
V
R
I
QKNVEIGANTA
I
D
R
A
V
--
F
G
E
T
L
I
KEGVK
I
D
N
L
V
Q
IGH
N
C
VLGEH
S
I
V
V
S
QVGLSGSTTTG
R
N
V
V
F
GGQVGIGG
H
L
HVG
E
F
TQIGGKSAVGKDLPPNTNFAGAIP
A
M
E
I
H
E
W
H
H
F
L
A
H
L
R
T
N
F
R
K
Q
Q
K
T
S
L
L
Q
K
A
K
G
FFKS
45
PsiBlast_CBE
80.16
32%
-125
- C2 -
2IU8
5
LPXD_CHLTR
C:
[28-362]
-------
L
E
Q
L
A
D
F
L
K
V
E
F
Q
G
N
G
A
T
L
L
S
G
V
E
E
I
E
E
A
K
T
A
H
I
T
F
L
D
N
E
K
Y
A
K
H
L
K
S
S
E
A
G
A
I
I
I
S
R
T
Q
F
Q
K
Y
--
R
D
L
N
K
--
N
F
L
I
TS
E
S
P
S
L
V
F
Q
K
C
L
E
L
F
I
T
P
------
V
D
S
GFPGI
H
P
T
A
V
---
I
H
----------
P
-------
T
A
-----
I
IE
D
H
V
C
I
E
P
Y
A
V
V
C
Q
H
A
H
V
------
G
S
A
C
H
I
G
S
G
S
V
I
G
A
Y
S
T
V
G
E
H
S
Y
------------
I
H
P
R
V
V
I
R
E
R
V
S
I
G
K
R
V
I
I
Q
P
G
A
V
I
G
S
C
G
F
G
Y
V
----------
T
S
A
F
G
---
Q
H
K
H
L
K
H
--
L
G
K
V
I
I
E
D
D
V
E
I
G
A
N
T
T
I
D
R
G
R
--
F
K
H
S
V
V
R
E
G
S
K
I
D
N
L
V
Q
I
A
H
Q
V
E
V
G
Q
H
S
M
I
V
A
Q
A
G
I
A
G
S
T
K
I
G
N
H
V
I
I
G
G
Q
A
G
I
T
G
H
I
C
I
A
D
H
V
I
M
M
A
Q
T
G
V
T
K
S
I
T
S
P
G
I
Y
G
G
A
-
P
A
R
P
Y
Q
E
I
H
R
Q
V
A
K
V
R
N
L
P
R
L
E
E
R
I
A
A
L
E
K
L
V
Q
K
L
E
-
41
PsiBlast_CBE
79.12
32%
-122
- C2 -
2IUA
4
LPXD_CHLTR
C:
[28-362]
-------
L
E
Q
L
A
D
F
L
K
V
E
F
Q
G
N
G
A
T
L
L
S
G
V
E
E
I
E
E
A
K
T
A
H
I
T
F
L
D
N
E
K
Y
A
K
H
L
K
S
S
E
A
G
A
I
I
I
S
R
T
Q
F
Q
K
Y
--
R
D
L
N
K
--
N
F
L
I
TS
E
S
P
S
L
V
F
Q
K
C
L
E
L
F
I
T
P
------
V
D
S
GFPGI
H
P
T
A
V
---
I
H
----------
P
-------
T
A
-----
I
IE
D
H
V
C
I
E
P
Y
A
V
V
C
Q
H
A
H
V
------
G
S
A
C
H
I
G
S
G
S
V
I
G
A
Y
S
T
V
G
E
H
S
Y
------------
I
H
P
R
V
V
I
R
E
R
V
S
I
G
K
R
V
I
I
Q
P
G
A
V
I
G
S
C
G
F
G
Y
V
----------
T
S
A
F
G
---
Q
H
K
H
L
K
H
--
L
G
K
V
I
I
E
D
D
V
E
I
G
A
N
T
T
I
D
R
G
R
--
F
K
H
S
V
V
R
E
G
S
K
I
D
N
L
V
Q
I
A
H
Q
V
E
V
G
Q
H
S
M
I
V
A
Q
A
G
I
A
G
S
T
K
I
G
N
H
V
I
I
G
G
Q
A
G
I
T
G
H
I
C
I
A
D
H
V
I
M
M
A
Q
T
G
V
T
K
S
I
T
S
P
G
I
Y
G
G
A
-
P
A
R
P
Y
Q
E
I
H
R
Q
V
A
K
V
R
N
L
P
R
L
E
E
R
I
A
A
L
E
K
L
V
Q
K
L
E
-
43
PsiBlast_CBE
78.77
32%
-128
- C2 -
2IU9
6
LPXD_CHLTR
C:
[28-362]
-------
L
E
Q
L
A
D
F
L
K
V
E
F
Q
G
N
G
A
T
L
L
S
G
V
E
E
I
E
E
A
K
T
A
H
I
T
F
L
D
N
E
K
Y
A
K
H
L
K
S
S
E
A
G
A
I
I
I
S
R
T
Q
F
Q
K
Y
--
R
D
L
N
K
--
N
F
L
I
TS
E
S
P
S
L
V
F
Q
K
C
L
E
L
F
I
T
P
------
V
D
S
GFPGI
H
P
T
A
V
---
I
H
----------
P
-------
T
A
-----
I
IE
D
H
V
C
I
E
P
Y
A
V
V
C
Q
H
A
H
V
------
G
S
A
C
H
I
G
S
G
S
V
I
G
A
Y
S
T
V
G
E
H
S
Y
------------
I
H
P
R
V
V
I
R
E
R
V
S
I
G
K
R
V
I
I
Q
P
G
A
V
I
G
S
C
G
F
G
Y
V
----------
T
S
A
F
G
---
Q
H
K
H
L
K
H
--
L
G
K
V
I
I
E
D
D
V
E
I
G
A
N
T
T
I
D
R
G
R
--
F
K
H
S
V
V
R
E
G
S
K
I
D
N
L
V
Q
I
A
H
Q
V
E
V
G
Q
H
S
M
I
V
A
Q
A
G
I
A
G
S
T
K
I
G
N
H
V
I
I
G
G
Q
A
G
I
T
G
H
I
C
I
A
D
H
V
I
M
M
A
Q
T
G
V
T
K
S
I
T
S
P
G
I
Y
G
G
A
-
P
A
R
P
Y
Q
E
I
H
R
Q
V
A
K
V
R
N
L
P
R
L
E
E
R
I
A
A
L
E
K
L
V
Q
K
L
E
-
22
PsiBlast_PDB
78.68
32%
-127
- C2 -
2IU9
8
LPXD_CHLTR
A:
[28-362]
-------
L
E
Q
L
A
D
F
L
K
V
E
F
Q
G
N
G
A
T
L
L
S
G
V
E
E
I
E
E
A
K
T
A
H
I
T
F
L
D
N
E
K
Y
A
K
H
L
K
S
S
E
A
G
A
I
I
I
S
R
T
Q
F
Q
K
Y
--
R
D
L
N
K
--
N
F
L
I
TS
E
S
P
S
L
V
F
Q
K
C
L
E
L
F
I
T
P
------
V
D
S
GFPGI
H
P
T
A
V
---
I
H
----------
P
-------
T
A
-----
I
I
E
D
H
V
C
I
E
P
Y
A
V
V
C
Q
H
A
H
V
------
G
S
A
C
H
I
G
S
G
S
V
I
G
A
Y
S
T
V
G
E
H
S
Y
------------
I
H
P
R
V
V
I
R
E
R
V
S
I
G
K
R
V
I
I
Q
P
G
A
V
I
G
S
C
G
F
G
Y
V
----------
T
S
A
F
G
---
Q
H
K
H
L
K
H
--
L
G
K
V
I
I
E
D
D
V
E
I
G
A
N
T
T
I
D
R
G
R
--
F
K
H
S
V
V
R
E
G
S
K
I
D
N
L
V
Q
I
A
H
Q
V
E
V
G
Q
H
S
M
I
V
A
Q
A
G
I
A
G
S
T
K
I
G
N
H
V
I
I
G
G
Q
A
G
I
T
G
H
I
C
I
A
D
H
V
I
M
M
A
Q
T
G
V
T
K
S
I
T
S
P
G
I
Y
G
G
A
-
P
A
R
P
Y
Q
E
I
H
R
Q
V
A
K
V
R
N
L
P
R
L
E
E
R
I
A
A
L
E
K
L
V
Q
K
---
23
PsiBlast_PDB
78.51
32%
-126
- C2 -
2IUA
6
LPXD_CHLTR
A:
[28-362]
-------
L
E
Q
L
A
D
F
L
K
V
E
F
Q
G
N
G
A
T
L
L
S
G
V
E
E
I
E
E
A
K
T
A
H
I
T
F
L
D
N
E
K
Y
A
K
H
L
K
S
S
E
A
G
A
I
I
I
S
R
T
Q
F
Q
K
Y
--
R
D
L
N
K
--
N
F
L
I
TS
E
S
P
S
L
V
F
Q
K
C
L
E
L
F
I
T
P
------
V
D
S
GFPGI
H
P
T
A
V
---
I
H
----------
P
-------
T
A
-----
I
I
E
D
H
V
C
I
E
P
Y
A
V
V
C
Q
H
A
H
V
------
G
S
A
C
H
I
G
S
G
S
V
I
G
A
Y
S
T
V
G
E
H
S
Y
------------
I
H
P
R
V
V
I
R
E
R
V
S
I
G
K
R
V
I
I
Q
P
G
A
V
I
G
S
C
G
F
G
Y
V
----------
T
S
A
F
G
---
Q
H
K
H
L
K
H
--
L
G
K
V
I
I
E
D
D
V
E
I
G
A
N
T
T
I
D
R
G
R
--
F
K
H
S
V
V
R
E
G
S
K
I
D
N
L
V
Q
I
A
H
Q
V
E
V
G
Q
H
S
M
I
V
A
Q
A
G
I
A
G
S
T
K
I
G
N
H
V
I
I
G
G
Q
A
G
I
T
G
H
I
C
I
A
D
H
V
I
M
M
A
Q
T
G
V
T
K
S
I
T
S
P
G
I
Y
G
G
A
-
P
A
R
P
Y
Q
E
I
H
R
Q
V
A
K
V
R
N
L
P
R
L
E
E
R
I
A
A
L
E
K
L
V
Q
K
---
44
PsiBlast_CBE
78.40
32%
-120
- C2 -
2IU9
7
LPXD_CHLTR
B:
[28-362]
-------
L
E
Q
L
A
D
F
L
K
V
E
F
Q
G
N
G
A
T
L
L
S
G
V
E
E
I
E
E
A
K
T
A
H
I
T
F
L
D
N
E
K
Y
A
K
H
L
K
S
S
E
A
G
A
I
I
I
S
R
T
Q
F
Q
K
Y
--
R
D
L
N
K
--
N
F
L
I
T
S
E
S
P
S
L
V
F
Q
K
C
L
E
L
F
I
T
P
------
V
D
S
GFPGI
H
P
T
A
V
---
I
H
----------
P
-------
T
A
-----
I
I
E
D
H
V
C
I
E
P
Y
A
V
V
C
Q
H
A
H
V
------
G
S
A
C
H
I
G
S
G
S
V
I
G
A
Y
S
T
V
G
E
H
S
Y
------------
I
H
P
R
V
V
I
R
E
R
V
S
I
G
K
R
V
I
I
Q
P
G
A
V
I
G
S
C
G
F
G
Y
V
----------
T
S
A
F
G
---
Q
H
K
H
L
K
H
--
L
G
K
V
I
I
E
D
D
V
E
I
G
A
N
T
T
I
D
R
G
R
--
F
K
H
S
V
V
R
E
G
S
K
I
D
N
L
V
Q
I
A
H
Q
V
E
V
G
Q
H
S
M
I
V
A
Q
A
G
I
A
G
S
T
K
I
G
N
H
V
I
I
G
G
Q
A
G
I
T
G
H
I
C
I
A
D
H
V
I
M
M
A
Q
T
G
V
T
K
S
I
T
S
P
G
I
Y
G
G
A
-
P
A
R
P
Y
Q
E
I
H
R
Q
V
A
K
V
R
N
L
P
R
L
E
E
R
I
A
A
L
E
K
L
V
Q
----
42
PsiBlast_CBE
78.10
32%
-122
- C2 -
2IUA
5
LPXD_CHLTR
B:
[28-362]
-------
L
E
Q
L
A
D
F
L
K
V
E
F
Q
G
N
G
A
T
L
L
S
G
V
E
E
I
E
E
A
K
T
A
H
I
T
F
L
D
N
E
K
Y
A
K
H
L
K
S
S
E
A
G
A
I
I
I
S
R
T
Q
F
Q
K
Y
--
R
D
L
N
K
--
N
F
L
I
T
S
E
S
P
S
L
V
F
Q
K
C
L
E
L
F
I
T
P
------
V
D
S
GFPGI
H
P
T
A
V
---
I
H
----------
P
-------
T
A
-----
I
I
E
D
H
V
C
I
E
P
Y
A
V
V
C
Q
H
A
H
V
------
G
S
A
C
H
I
G
S
G
S
V
I
G
A
Y
S
T
V
G
E
H
S
Y
------------
I
H
P
R
V
V
I
R
E
R
V
S
I
G
K
R
V
I
I
Q
P
G
A
V
I
G
S
C
G
F
G
Y
V
----------
T
S
A
F
G
---
Q
H
K
H
L
K
H
--
L
G
K
V
I
I
E
D
D
V
E
I
G
A
N
T
T
I
D
R
G
R
--
F
K
H
S
V
V
R
E
G
S
K
I
D
N
L
V
Q
I
A
H
Q
V
E
V
G
Q
H
S
M
I
V
A
Q
A
G
I
A
G
S
T
K
I
G
N
H
V
I
I
G
G
Q
A
G
I
T
G
H
I
C
I
A
D
H
V
I
M
M
A
Q
T
G
V
T
K
S
I
T
S
P
G
I
Y
G
G
A
-
P
A
R
P
Y
Q
E
I
H
R
Q
V
A
K
V
R
N
L
P
R
L
E
E
R
I
A
A
L
E
K
L
V
Q
----
46
PsiBlast_CBE
77.81
32%
-123
- C2 -
2IU8
6
LPXD_CHLTR
B:
[28-362]
-------
L
E
Q
L
A
D
F
L
K
V
E
F
Q
G
N
G
A
T
L
L
S
G
V
E
E
I
E
E
A
K
T
A
H
I
T
F
L
D
N
E
K
Y
A
K
H
L
K
S
S
E
A
G
A
I
I
I
S
R
T
Q
F
Q
K
Y
--
R
D
L
N
K
--
N
F
L
I
T
S
E
S
P
S
L
V
F
Q
K
C
L
E
L
F
I
T
P
------
V
D
S
GFPGI
H
P
T
A
V
---
I
H
----------
P
-------
T
A
-----
I
I
E
D
H
V
C
I
E
P
Y
A
V
V
C
Q
H
A
H
V
------
G
S
A
C
H
I
G
S
G
S
V
I
G
A
Y
S
T
V
G
E
H
S
Y
------------
I
H
P
R
V
V
I
R
E
R
V
S
I
G
K
R
V
I
I
Q
P
G
A
V
I
G
S
C
G
F
G
Y
V
----------
T
S
A
F
G
---
Q
H
K
H
L
K
H
--
L
G
K
V
I
I
E
D
D
V
E
I
G
A
N
T
T
I
D
R
G
R
--
F
K
H
S
V
V
R
E
G
S
K
I
D
N
L
V
Q
I
A
H
Q
V
E
V
G
Q
H
S
M
I
V
A
Q
A
G
I
A
G
S
T
K
I
G
N
H
V
I
I
G
G
Q
A
G
I
T
G
H
I
C
I
A
D
H
V
I
M
M
A
Q
T
G
V
T
K
S
I
T
S
P
G
I
Y
G
G
A
-
P
A
R
P
Y
Q
E
I
H
R
Q
V
A
K
V
R
N
L
P
R
L
E
E
R
I
A
A
L
E
K
L
V
Q
----
21
PsiBlast_PDB
76.96
32%
-126
- C2 -
2IU8
9
LPXD_CHLTR
A:
[28-362]
-------
L
E
Q
L
A
D
F
L
K
V
E
F
Q
G
N
G
A
T
L
L
S
G
V
E
E
I
E
E
A
K
T
A
H
I
T
F
L
D
N
E
K
Y
A
K
H
L
K
S
S
E
A
G
A
I
I
I
S
R
T
Q
F
Q
K
Y
--
R
D
L
N
K
--
N
F
L
I
TS
E
S
P
S
L
V
F
Q
K
C
L
E
L
F
I
T
P
------
V
D
S
GFPGI
H
P
T
A
V
---
I
H
----------
P
-------
T
A
-----
I
I
E
D
H
V
C
I
E
P
Y
A
V
V
C
Q
H
A
H
V
------
G
S
A
C
H
I
G
S
G
S
V
I
G
A
Y
S
T
V
G
E
H
S
Y
------------
I
H
P
R
V
V
I
R
E
R
V
S
I
G
K
R
V
I
I
Q
P
G
A
V
I
G
S
C
G
F
G
Y
V
----------
T
S
A
F
G
---
Q
H
K
H
L
K
H
--
L
G
K
V
I
I
E
D
D
V
E
I
G
A
N
T
T
I
D
R
G
R
--
F
K
H
S
V
V
R
E
G
S
K
I
D
N
L
V
Q
I
A
H
Q
V
E
V
G
Q
H
S
M
I
V
A
Q
A
G
I
A
G
S
T
K
I
G
N
H
V
I
I
G
G
Q
A
G
I
T
G
H
I
C
I
A
D
H
V
I
M
M
A
Q
T
G
V
T
K
S
I
T
S
P
G
I
Y
G
G
A
-
P
A
R
P
Y
Q
E
I
H
R
Q
V
A
K
V
R
N
L
P
R
L
E
E
R
I
A
A
L
E
K
L
V
Q
K
---
131
Fugue
76.29
32%
-124
- C2 -
2IU8
9
LPXD_CHLTR
A:
[21-366]
MSQ
S
T
Y
S
L
E
Q
L
A
D
F
L
K
V
E
F
Q
G
N
G
A
T
L
L
S
G
V
E
E
I
E
E
A
K
T
A
H
I
T
F
L
D
N
E
K
Y
A
K
H
L
K
S
S
E
A
G
A
I
I
I
S
R
T
Q
F
Q
K
Y
--
R
D
L
N
K
NF
L
I
T
S
--
E
S
P
S
L
V
F
Q
K
C
L
E
L
F
I
T
P
------
V
D
S
-----
G
F
P
G
I
---
H
P
----------
T
A
V
I
H
PT
A
I
I
-----
E
--
D
H
V
C
I
E
P
Y
A
V
V
C
Q
H
A
H
V
------
G
S
A
C
H
I
G
S
G
S
V
I
G
A
Y
S
T
V
G
E
H
S
Y
------------
I
H
P
R
V
V
I
R
E
R
V
S
I
G
K
R
V
I
I
Q
P
G
A
V
I
G
S
C
G
F
G
Y
V
----------
T
S
A
F
G
---
Q
H
K
H
L
K
H
--
L
G
K
V
I
I
E
D
D
V
E
I
G
A
N
T
T
I
D
R
G
R
--
F
K
H
S
V
V
R
E
G
S
K
I
D
N
L
V
Q
I
A
H
Q
V
E
V
G
Q
H
S
M
I
V
A
Q
A
G
I
A
G
S
T
K
I
G
N
H
V
I
I
G
G
Q
A
G
I
T
G
H
I
C
I
A
D
H
V
I
M
M
A
Q
T
G
V
T
K
S
I
T
S
P
G
I
Y
G
G
A
-
P
A
R
P
Y
Q
E
I
H
R
Q
V
A
K
V
R
N
L
P
R
L
E
E
R
I
A
A
L
E
K
L
V
Q
K
---
1
HHSearch
75.55
32%
-117
- C2 -
3PMO
3
LPXD_PSEAE
A:
[26-359]
-----
Y
T
L
G
Q
L
A
A
H
V
G
A
E
V
R
G
D
A
D
L
P
I
Q
G
L
A
T
L
Q
E
A
G
P
A
Q
L
S
F
L
A
N
P
Q
Y
R
K
Y
L
P
E
S
R
A
G
A
V
L
L
T
A
A
D
A
D
----
G
F
A
G
T
--
A
L
V
V
--
A
N
P
Y
L
A
Y
A
S
L
S
H
L
F
D
R
K
------
P
K
A
A
A
G--
I
H
P
T
A
I
V
A
A
D
----------
A
-------
E
V
-----
D
--
P
S
A
S
V
G
A
Y
A
V
I
E
S
G
A
R
I
------
G
A
G
V
S
I
G
A
H
C
V
I
G
A
R
S
V
I
G
E
G
G
W
------------
L
A
P
R
V
T
L
Y
H
D
V
T
I
G
A
R
V
S
I
Q
S
G
A
V
I
G
G
E
G
F
G
F
A
----------
N
E
-
K
G
---
V
W
Q
K
I
A
Q
--
I
G
G
V
T
I
G
D
D
V
E
I
G
A
N
T
T
I
D
R
G
A
--
L
S
D
T
L
I
G
N
G
V
K
L
D
N
Q
I
M
I
A
H
N
V
Q
I
G
D
H
T
A
M
A
A
C
V
G
I
S
G
S
A
K
I
G
R
H
C
M
L
A
G
G
V
G
L
V
G
H
I
E
I
C
D
N
V
F
V
T
G
M
T
M
V
T
R
S
I
T
E
P
G
S
Y
S
S
G
T
A
M
Q
P
A
A
E
W
K
K
S
A
A
R
I
R
Q
L
D
D
M
A
R
R
L
Q
Q
L
E
K
R
L
-----
2
HHSearch
75.51
32%
-119
- C2 -
2IU8
9
LPXD_CHLTR
A:
[26-366]
-----
Y
S
L
E
Q
L
A
D
F
L
K
V
E
F
Q
G
N
G
A
T
L
L
S
G
V
E
E
I
E
E
A
K
T
A
H
I
T
F
L
D
N
E
K
Y
A
K
H
L
K
S
S
E
A
G
A
I
I
I
S
R
T
Q
F
Q
K
Y
RD
L
N
K
N
F
--
L
I
T
S
--
E
S
P
S
L
V
F
Q
K
C
L
E
L
F
I
T
P
------
V
D
S
GFPG-
I
H
P
T
A
V
I
H
P
T
----------
A
-------
I
I
-----
E
--
D
H
V
C
I
E
P
Y
A
V
V
C
Q
H
A
H
V
------
G
S
A
C
H
I
G
S
G
S
V
I
G
A
Y
S
T
V
G
E
H
S
Y
------------
I
H
P
R
V
V
I
R
E
R
V
S
I
G
K
R
V
I
I
Q
P
G
A
V
I
G
S
C
G
F
G
Y
V
----------
T
S
A
F
G
---
Q
H
K
H
L
K
H
--
L
G
K
V
I
I
E
D
D
V
E
I
G
A
N
T
T
I
D
R
G
R
--
F
K
H
S
V
V
R
E
G
S
K
I
D
N
L
V
Q
I
A
H
Q
V
E
V
G
Q
H
S
M
I
V
A
Q
A
G
I
A
G
S
T
K
I
G
N
H
V
I
I
G
G
Q
A
G
I
T
G
H
I
C
I
A
D
H
V
I
M
M
A
Q
T
G
V
T
K
S
I
T
S
P
G
I
-
Y
G
G
A
P
A
R
P
Y
Q
E
I
H
R
Q
V
A
K
V
R
N
L
P
R
L
E
E
R
I
A
A
L
E
K
L
V
Q
K
---
28
PsiBlast_PDB
73.56
30%
-127
- C2 -
4IHH
7
LPXD_ECOLI
A:
[11-325]
-----
I
R
L
A
D
L
A
Q
Q
L
D
A
E
L
H
G
D
G
D
I
V
I
T
G
V
A
S
M
Q
S
A
Q
T
G
H
I
T
F
M
V
N
P
K
Y
R
E
H
L
G
L
C
Q
A
S
A
V
V
M
T
Q
D
D
L
P
F
A
--
K
S
A
----
A
L
V
V
--
K
N
P
Y
L
T
Y
A
R
M
A
Q
I
L
D
----------
T
-----
T
P
Q
P
A
---
Q
N
IAPS
A
V
I
D
AT
A
-------
K
L
-----
G
--
N
N
V
S
I
G
A
N
A
V
I
E
S
G
V
E
L
------
G
D
N
V
I
I
G
A
G
C
F
V
G
K
N
S
K
I
G
A
G
S
R
------------
L
W
A
N
V
T
I
Y
H
E
I
Q
I
G
Q
N
C
L
I
Q
S
G
T
V
V
G
A
D
G
F
G
Y
A
----------
N
D
R
-
G
---
N
W
V
K
I
P
Q
--
I
G
R
V
I
I
G
D
R
V
E
I
G
A
C
T
T
I
D
R
G
A
--
L
D
D
T
I
I
G
N
G
V
I
I
D
N
Q
C
Q
I
A
H
N
V
V
I
G
D
N
T
A
V
A
G
G
V
I
M
A
G
S
L
K
I
G
R
Y
C
M
I
G
G
A
S
V
I
N
G
H
M
E
I
C
D
K
V
T
V
T
G
M
G
M
V
M
R
P
I
T
E
P
G
V
Y
S
S
G
I
P
L
Q
P
N
K
V
W
R
K
T
A
A
L
V
M
N
I
D
D
M
S
K
R
L
K
S
L
E
R
K
V
-----
24
PsiBlast_PDB
72.76
31%
-113
- C2 -
3PMO
3
LPXD_PSEAE
A:
[28-357]
-------
L
G
Q
L
A
A
H
V
G
A
E
V
R
G
D
A
D
L
P
I
Q
G
L
A
T
L
Q
E
A
G
P
A
Q
L
S
F
L
A
N
P
Q
Y
R
K
Y
L
P
E
S
R
A
G
A
V
L
L
T
A
A
D
A
D
G
F
--
A
G
T
----
A
L
V
V
--
A
N
P
Y
L
A
Y
A
S
L
S
H
L
F
D
------------------------
R
K
----------
P
-------
K
---------
A
A
A
G
I
H
P
T
A
I
V
A
A
D
A
E
V
D
PS
A
S
V
G
A
Y
A
V
I
E
S
G
A
R
I
G
A
G
V
S
I
G
A
H
C
V
I
G
A
R
S
V
I
G
E
G
G
W
L
A
P
R
V
T
L
Y
H
D
V
T
I
G
A
R
V
S
I
Q
S
G
A
V
I
G
G
E
G
F
G
F
A
----------
N
E
K
-
G
---
V
W
Q
K
I
A
Q
--
I
G
G
V
T
I
G
D
D
V
E
I
G
A
N
T
T
I
D
R
G
A
--
L
S
D
T
L
I
G
N
G
V
K
L
D
N
Q
I
M
I
A
H
N
V
Q
I
G
D
H
T
A
M
A
A
C
V
G
I
S
G
S
A
K
I
G
R
H
C
M
L
A
G
G
V
G
L
V
G
H
I
E
I
C
D
N
V
F
V
T
G
M
T
M
V
T
R
S
I
T
E
P
G
S
Y
S
S
G
T
A
M
Q
P
A
A
E
W
K
K
S
A
A
R
I
R
Q
L
D
D
M
A
R
R
L
Q
Q
L
E
K
R
L
-----
29
PsiBlast_PDB
71.05
29%
-126
- C2 -
4IHF
3
LPXD_ECOLI
A:
[11-325]
-----
I
R
L
A
D
L
A
Q
Q
L
D
A
E
L
H
G
D
G
D
I
V
I
T
G
V
A
S
M
Q
S
A
Q
T
G
H
I
T
F
M
V
N
P
K
Y
R
E
H
L
G
L
C
Q
A
S
A
V
V
M
T
Q
D
D
L
P
F
A
--
K
S
A
----
A
L
V
V
--
K
N
P
Y
L
T
Y
A
R
M
A
Q
I
L
D
----------
T
-----
T
P
Q
P
A
---
Q
N
IAPS
A
V
I
D
AT
A
-------
K
L
-----
G
--
N
N
V
S
I
G
A
N
A
V
I
E
S
G
V
E
L
------
G
D
N
V
I
I
G
A
G
C
F
V
G
K
N
S
K
I
G
A
G
S
R
------------
L
W
A
N
V
T
I
Y
H
E
I
Q
I
G
Q
N
C
L
I
Q
S
G
T
V
V
G
A
D
G
F
G
Y
A
----------
N
D
R
-
G
---
N
W
V
K
I
P
Q
--
I
G
R
V
I
I
G
D
R
V
E
I
G
A
C
T
T
I
D
R
G
A
--
L
D
D
T
I
I
G
N
G
V
I
I
D
N
Q
C
Q
I
A
A
N
V
V
I
G
D
N
T
A
V
A
G
G
V
I
M
A
G
S
L
K
I
G
R
Y
C
M
I
G
G
A
S
V
I
N
G
H
M
E
I
C
D
K
V
T
V
T
G
M
G
M
V
M
R
P
I
T
E
P
G
V
Y
S
S
G
I
P
L
Q
P
N
K
V
W
R
K
T
A
A
L
V
M
N
I
D
D
M
S
K
R
L
K
S
L
E
R
K
V
N
----
130
Fugue
70.94
28%
-126
- C1 -
3EH0
-
LPXD_ECOLI
A:
[1-341]
--MAS
I
R
L
A
D
L
A
Q
Q
L
D
A
E
L
H
G
D
G
D
I
V
I
T
G
V
A
S
M
Q
S
A
Q
T
G
H
I
T
F
M
V
N
P
K
Y
R
E
H
L
G
L
C
Q
A
S
A
V
V
M
T
Q
D
D
L
P
F
A
--
K
S
A
----
A
L
V
V
--
K
N
P
Y
L
T
Y
A
R
M
A
Q
I
L
D
T
T
PQPAQN
I
A
P
-----
S
A
V
I
D
---
A
T
----------
A
-------
K
L
-----
G
--
N
N
V
S
I
G
A
N
A
V
I
E
S
G
V
E
L
------
G
D
N
V
I
I
G
A
G
C
F
V
G
K
N
S
K
I
G
A
G
S
R
------------
L
W
A
N
V
T
I
Y
H
E
I
Q
I
G
Q
N
C
L
I
Q
S
G
T
V
V
G
A
D
G
F
G
Y
A
----------
N
D
R
-
G
---
N
W
V
K
I
P
Q
--
I
G
R
V
I
I
G
D
R
V
E
I
G
A
C
T
T
I
D
R
G
A
--
L
D
D
T
I
I
G
N
G
V
I
I
D
N
Q
C
Q
I
A
H
N
V
V
I
G
D
N
T
A
V
A
G
G
V
I
M
A
G
S
L
K
I
G
R
Y
C
M
I
G
G
A
S
V
I
N
G
H
M
E
I
C
D
K
V
T
V
T
G
M
G
M
V
M
R
P
I
T
E
P
G
V
Y
S
S
G
I
P
L
Q
P
N
K
V
W
R
K
T
A
A
L
V
M
N
I
D
D
M
S
K
R
L
K
S
L
E
R
K
V
N
Q
Q
D
-
27
PsiBlast_PDB
70.94
30%
-131
- C2 -
3EH0
-
LPXD_ECOLI
A:
[4-318]
-----
I
R
L
A
D
L
A
Q
Q
L
D
A
E
L
H
G
D
G
D
I
V
I
T
G
V
A
S
M
Q
S
A
Q
T
G
H
I
T
F
M
V
N
P
K
Y
R
E
H
L
G
L
C
Q
A
S
A
V
V
M
T
Q
D
D
L
P
F
A
--
K
S
A
----
A
L
V
V
--
K
N
P
Y
L
T
Y
A
R
M
A
Q
I
L
D
----------
T
-----
T
P
Q
P
A
---
Q
N
IAPS
A
V
I
D
AT
A
-------
K
L
-----
G
--
N
N
V
S
I
G
A
N
A
V
I
E
S
G
V
E
L
------
G
D
N
V
I
I
G
A
G
C
F
V
G
K
N
S
K
I
G
A
G
S
R
------------
L
W
A
N
V
T
I
Y
H
E
I
Q
I
G
Q
N
C
L
I
Q
S
G
T
V
V
G
A
D
G
F
G
Y
A
----------
N
D
R
-
G
---
N
W
V
K
I
P
Q
--
I
G
R
V
I
I
G
D
R
V
E
I
G
A
C
T
T
I
D
R
G
A
--
L
D
D
T
I
I
G
N
G
V
I
I
D
N
Q
C
Q
I
A
H
N
V
V
I
G
D
N
T
A
V
A
G
G
V
I
M
A
G
S
L
K
I
G
R
Y
C
M
I
G
G
A
S
V
I
N
G
H
M
E
I
C
D
K
V
T
V
T
G
M
G
M
V
M
R
P
I
T
E
P
G
V
Y
S
S
G
I
P
L
Q
P
N
K
V
W
R
K
T
A
A
L
V
M
N
I
D
D
M
S
K
R
L
K
S
L
E
R
K
V
N
Q
Q
D
-
26
PsiBlast_PDB
70.27
32%
-118
- C2 -
4E79
-
LPXD_ACIBS
A:
[28-326]
-------------------
Q
F
S
N
------
L
A
S
L
E
N
A
E
V
N
H
L
T
F
V
N
G
E
K
H
L
D
Q
A
K
V
S
R
A
G
A
Y
I
V
T
A
A
L
K
E
H
L
--
P
E
K
D
N
--
F
I
I
V
--
D
N
P
Y
L
A
F
A
I
L
T
H
V
F
D
K
K
------
I
S
S
-----
T
G
I
E
S
---
T
A
----------
R
-------
I
H
PS
A
V
I
S
--
E
T
A
Y
I
G
H
Y
V
V
I
G
E
N
C
V
V
------
G
D
N
T
V
I
Q
S
H
T
K
L
D
D
N
V
E
V
G
K
D
C
F
------------
I
D
S
Y
V
T
I
T
G
S
S
K
L
R
D
R
V
R
I
H
S
S
T
V
I
G
G
E
G
F
G
F
A
----------
P
Y
Q
-
G
---
K
W
H
R
I
A
Q
--
L
G
S
V
L
I
G
N
D
V
R
I
G
S
N
C
S
I
D
R
G
A
--
L
D
N
T
I
L
E
D
G
V
I
I
D
N
L
V
Q
I
A
H
N
V
H
I
G
S
N
T
A
I
A
A
K
C
G
I
A
G
S
T
K
I
G
K
N
C
I
L
A
G
A
C
G
V
A
G
H
L
S
I
A
D
N
V
T
L
T
G
M
S
M
V
T
K
N
I
S
E
A
G
T
Y
S
S
G
T
G
L
F
E
N
N
H
W
K
K
T
I
V
R
L
R
Q
L
A
D
V
P
L
T
Q
I
T
K
R
L
D
H
I
Q
A
Q
I
25
PsiBlast_PDB
69.44
32%
-122
- C2 -
4E75
-
LPXD_ACIBS
A:
[28-326]
-------------------
Q
F
S
N
------
L
A
S
L
E
N
A
E
V
N
H
L
T
F
V
N
G
E
K
H
L
D
Q
A
K
V
S
R
A
G
A
Y
I
V
T
A
A
L
K
E
H
L
--
P
E
K
D
N
--
F
I
I
V
--
D
N
P
Y
L
A
F
A
I
L
T
H
V
F
D
K
K
------
I
S
S
-----
T
G
I
E
S
---
T
A
----------
R
-------
I
H
PS
A
V
I
S
--
E
T
A
Y
I
G
H
Y
V
V
I
G
E
N
C
V
V
------
G
D
N
T
V
I
Q
S
H
T
K
L
D
D
N
V
E
V
G
K
D
C
F
------------
I
D
S
Y
V
T
I
T
G
S
S
K
L
R
D
R
V
R
I
H
S
S
T
V
I
G
G
E
G
F
G
F
A
----------
P
Y
Q
-
G
---
K
W
H
R
I
A
Q
--
L
G
S
V
L
I
G
N
D
V
R
I
G
S
N
C
S
I
D
R
G
A
--
L
D
N
T
I
L
E
D
G
V
I
I
D
N
L
V
Q
I
A
H
N
V
H
I
G
S
N
T
A
I
A
A
K
C
G
I
A
G
S
T
K
I
G
K
N
C
I
L
A
G
A
C
G
V
A
G
H
L
S
I
A
D
N
V
T
L
T
G
M
S
M
V
T
K
N
I
S
E
A
G
T
Y
S
S
G
T
G
L
F
E
N
N
H
W
K
K
T
I
V
R
L
R
Q
L
A
D
V
P
L
T
Q
I
T
K
R
L
D
------
30
PsiBlast_PDB
52.86
28%
-144
- C2 -
3T57
-
LPXA_ARATH
A:
[47-244]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
V
H
P
N
A
V
I
G
K
G
V
S
V
------
G
------
P
Y
C
T
I
G
S
S
V
K
L
G
N
G
C
K
------------
L
Y
P
S
S
H
V
F
G
N
T
E
L
G
E
S
C
V
L
M
T
G
A
V
V
G
D
E
L
P
G
Y
T
F
I
G
C
N
N
I
I
G
H
H
A
V
V
G
VKC
Q
D
L
K
Y
K
H
G
D
E
C
F
L
C
I
G
N
N
N
E
I
R
E
F
C
S
I
H
R
S
S
KP
S
D
K
T
V
I
G
D
N
N
L
I
M
G
S
C
H
I
A
H
D
C
K
I
G
D
R
N
I
F
A
N
N
T
L
L
A
G
H
V
V
V
E
D
N
T
H
T
A
G
A
S
V
V
H
Q
F
C
H
I
G
S
F
A
F
I
G
G
G
S
V
V
S
Q
D
V
P
K
Y
M
M
V
A
G
E
R
A
E
L
R
G
L
N
L
E
G
L
R
R
N
G
F
T
M
S
E
M
K
S
L
R
A
A
Y
R
K
I
F
M
S
T
E
T