@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0193: (2015-12-13 )
MLTQEDVLNALKTIIYPNFEKDIVSFGFVKNITLHDNQLGLLIEIPSSSEETSAILRENISKAMQEKGVKALNLDIKTPPKPQAPKPTTKNLAKNIKHVVMISSGKGGVGKSTTSVNLSIALANLNQKVGLLDADVYGPNIPRMMGLQNADVIMDPSGKKLIPLKAFGVSVMSMGLLYDEGQSLIWRGPMLMRAIEQMLSDIIWGDLDVLVVDMPPGTGDAQLTLAQAVPLSAGITVTTPQIVSLDDAKRSLDMFKKLHIPIAGIVENMGSFVCEHCKKESEIFGSNSMSGLLEAYNTQILAKLPLEPKVRLGGDKGEPIVISHPTSVSAKIFEKMAKDLSAFLDKVEREKLADNKDIQPTQTHAYSH
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100-.......110.......120.......130.......140....-------...150-------.-.--...------.------..-----------.160..----.....170.-.-.-....180.--......190..-.....200..---.---.----------.---....210.....-..220-....-....230.--......240.......250.-....----..-----260......-.270.......280....-...290.......300.......310.......320.....----..330.......340.......350.......360......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
ML
T
Q
E
D
V
L
N
A
L
K
T
I
IYPN
F
E
K
D
I
V
SFG
F
V
K
N
I
T
LHDNQ
L
G
L
L
I
EIPSSS
E
E
T
S
A
I
L
R
E
N
I
S
K
A
M
Q
EKG
V
K
A
L
N
L
D
IKTPPKPQAPKP
T
T
K
N
L
A
K
NI
K
H
V
V
M
I
-SSGKGGVGK
S
T
T
S
V
N
L
S
I
A
L
ANLNQKVGL
L
D
ADVYGPNI
P
R
M
MG-------LQNA---------
D
-
V
--
I
MD------P------SG-----------
K
K
L
I
P
L
----
K
A
F
G
V
S
V
M
S
-
M
-
G
-
L
L
YDEGQS--LIWR
G
P
M
L
M
R
A
-
I
E
Q
M
L
S
--
D
I
---I---W----------G---D
L
D
V
L
V
V
DMPPG-TGD-A-
Q
L
T
L
-
A
Q
AVPLSA--
G
I
T
VTT
P
Q
I
V
S
L
D
D
A
K
R
S
L
D
-
M
F
K
K
----LH-----I
P
I
A
G
I
V
E
N
-
M
G
S
F
V
C
E
H
C
K
K
E
S
E
IFGS-
N
S
M
S
G
L
L
E
A
YN
T
Q
I
L
A
KLPLEP
K
V
R
LGGDKGE
P
I
V
I
SHPT
S
----
V
S
A
K
I
F
E
K
M
A
K
D
L
S
A
F
L
D
K
V
E
R
E
KLADNKDIQPTQTHAYSH
1
PsiBlast_PDB
90.56
37%
-106
- C2 -
2PH1
1
?
A:
[17-229]
-----------------------------------------------------------------------------------------------
I
K
S
R
I
A
V
-
M
S
G
K
G
G
V
G
K
S
T
V
T
A
L
L
A
V
H
Y
A
R
Q
G
K
K
V
G
I
L
D
A
D
F
L
G
P
S
I
P
I
L
F
G
-------
L
R
N
A
---------
R
-
I
--
A
V
S
------
A
------
E
G
-----------
L
E
P
V
L
T
----
Q
K
Y
G
I
K
V
M
S
-
M
-
Q
F
L
L
P
K
E
N
T
P
--
V
I
W
R
G
P
L
I
A
G
M
-
I
R
E
F
L
G
--
R
V
---
A
---
W
----------
G
---
E
L
D
H
L
L
I
D
L
P
P
G
-
T
G
D
-
A
-
P
L
T
V
-
M
Q
D
A
K
P
T
G
--
V
V
V
V
S
T
P
Q
E
L
T
A
V
I
V
E
K
A
I
N
-
M
A
E
E
----
T
N
-----
T
S
V
L
G
L
V
E
N
-
M
S
Y
F
V
C
P
N
C
G
H
K
S
Y
I
F
G
E
-
G
K
G
E
S
L
A
K
K
Y
N
I
G
F
F
T
S
I
P
I
E
E
E
L
I
K
L
A
D
S
G
R
I
E
E
Y
E
K
D
W
F
----
E
----------------------------------------
135
Fugue
87.82
34%
-84
- C2 -
2PH1
1
?
A:
[4-250]
----------------------------------------------------------------------------------
R
V
T
D
E
E
I
K
E
R
L
G
K
I
K
S
R
I
A
V
M
S
-
G
K
G
G
V
G
K
S
T
V
T
A
L
L
A
V
H
Y
A
R
Q
G
K
K
V
G
I
L
D
A
D
F
L
G
P
S
I
P
I
L
F
G
-------
L
R
N
A
---------
R
-
I
--
A
V
S
------
A
------
E
G
-------------
L
E
P
V
----
L
T
Q
K
Y
G
I
K
V
M
S
M
Q
F
L
L
P
K
E
N
T
P
--
V
I
W
R
G
P
L
I
A
-
G
M
I
R
E
F
L
G
--
R
V
---
A
---
W
----------
G
---
E
L
D
H
L
L
I
D
L
P
P
G
-
T
G
D
-
A
-
P
L
T
V
M
Q
D
A
K
P
-
T
G
--
V
V
V
V
S
T
P
Q
E
L
T
A
V
I
V
E
K
A
I
N
M
A
-
E
E
----
T
N
-----
T
S
V
L
G
L
V
E
N
M
S
Y
-
F
V
C
P
N
C
G
H
K
S
Y
I
F
G
E
-
G
K
G
E
S
L
A
K
K
Y
N
I
G
F
F
T
S
I
P
I
E
E
E
L
I
K
L
A
D
S
G
R
I
E
E
Y
E
K
D
W
F
----
E
----------------------------------------
2
PsiBlast_PDB
87.00
33%
-109
- C2 -
3KB1
3
?
A:
[11-229]
-----------------------------------------------------------------------------------------
K
E
R
L
D
K
I
G
F
R
I
A
V
-
M
S
G
K
G
G
V
G
K
S
T
V
T
A
L
L
A
V
H
Y
A
K
Q
G
K
K
V
G
I
L
D
A
D
F
L
G
P
S
I
P
H
L
F
G
-------
L
E
K
G
---------
K
-
V
--
A
V
S
------
D
------
E
G
-----------
L
E
P
V
L
T
----
Q
R
L
G
I
K
V
M
S
-
I
-
Q
-
F
L
L
-------------
L
I
A
G
M
-
I
R
E
F
L
G
--
R
V
---
A
---
W
----------
G
---
E
L
D
Y
L
L
I
D
L
P
P
G
-
T
G
D
-
A
-
P
L
T
V
-
M
Q
D
A
K
P
N
G
--
A
V
I
V
S
T
P
Q
E
L
T
A
A
V
V
E
K
A
I
T
-
M
A
E
Q
----
T
K
-----
T
A
V
L
G
I
V
E
N
-
M
A
Y
F
E
C
P
N
C
G
E
R
T
Y
L
F
G
E
-
G
K
A
S
E
L
A
R
K
Y
K
I
E
F
I
T
E
I
P
I
D
S
D
L
L
K
L
S
D
L
G
R
V
E
E
Y
E
P
D
W
F
----
E
F
F
P
Y
L
E
H
H
--------------------------------
116
HHSearch
85.32
34%
-80
- C2 -
2PH1
1
?
A:
[14-248]
--------------------------------------------------------------------------------------------
L
G
K
I
K
S
R
I
A
V
-
M
S
G
K
G
G
V
G
K
S
T
V
T
A
L
L
A
V
H
Y
A
R
Q
G
K
K
V
G
I
L
D
A
D
F
L
G
P
S
I
P
I
L
F
G
-------
L
R
N
A
---------
R
-
I
--
A
V
S
AE----
G
------
L
E
-----------
P
V
L
T
Q
K
YGI
K
V
M
S
M
Q
F
L
L
P
-
K
-
E
-
N
T
P
-------
V
I
W
R
G
P
L
I
A
G
M
-
I
R
E
F
L
G
--
R
V
A--
W
--------------
G
---
E
L
D
H
L
L
I
D
L
P
P
G
-
T
G
D
-
A
-
P
L
T
V
-
M
Q
D
A
K
P
T
G
--
V
V
V
V
S
T
P
Q
E
L
T
A
V
I
V
E
K
A
I
N
-
M
A
E
E
----
T
N
-----
T
S
V
L
G
L
V
E
N
-
M
S
Y
F
V
C
P
N
C
G
H
K
S
Y
I
F
G
E
-
G
K
G
E
S
L
A
K
K
Y
N
I
G
F
F
T
S
I
P
I
E
E
E
L
I
K
L
A
D
S
G
R
I
E
E
Y
E
K
D
W
F
----
E
----------------------------------------
5
PsiBlast_PDB
84.96
29%
-113
- C3 -
5AUO
4
?
B:
[16-220]
---------------------------------------------------------------------------------------------
E
G
V
K
R
I
I
P
V
-
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
---------
E
-
F
--
P
E
E
------
D
------
R
G
-------------
V
V
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
-
Y
-
Y
T
E
D
R
P
--
T
P
L
R
G
K
E
I
S
D
A
-
L
I
E
L
L
T
--
I
T
---
R
---
W
----------
D
---
E
L
D
Y
L
V
I
D
M
P
P
G
-
L
G
D
-
Q
-
L
L
D
V
-
L
R
F
L
K
R
G
E
--
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
----
E
G
-----
H
K
V
I
G
V
V
E
N
-
M
-
K
L
--------
K
D
V
-------
E
K
L
A
E
E
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
F
A
G
----
K
V
R
E
L
A
G
R
L
--------------------------------
3
PsiBlast_PDB
84.90
29%
-110
- C3 -
3VX3
5
?
A:
[16-220]
---------------------------------------------------------------------------------------------
E
G
V
K
R
I
I
P
V
-
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
---------
E
-
F
--
P
E
E
------
D
------
R
G
-------------
V
V
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
-
Y
-
Y
T
------
T
P
L
R
G
K
E
I
S
D
A
-
L
I
E
L
L
T
--
I
T
---
R
---
W
----------
D
---
E
L
D
Y
L
V
I
D
M
P
P
G
-
L
G
D
-
Q
-
L
L
D
V
-
L
R
F
L
K
R
G
E
--
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
----
E
G
-----
H
K
V
I
G
V
V
E
N
-
M
-
K
L
R
------
E
K
D
V
-------
E
K
L
A
E
E
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
F
A
G
----
K
V
R
E
L
A
G
R
L
--------------------------------
4
PsiBlast_PDB
84.81
29%
-112
- C3 -
5AUN
4
?
B:
[16-220]
---------------------------------------------------------------------------------------------
E
G
V
K
R
I
I
P
V
-
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
---------
E
-
F
--
P
E
E
------
D
------
R
G
-------------
V
V
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
-
Y
-
Y
T
E
D
R
P
--
T
P
L
R
G
K
E
I
S
D
A
-
L
I
E
L
L
T
--
I
T
---
R
---
W
----------
D
---
E
L
D
Y
L
V
I
D
M
P
P
G
-
L
G
D
-
Q
-
L
L
D
V
-
L
R
F
L
K
R
G
E
--
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
----
E
G
-----
H
K
V
I
G
V
V
E
N
-
M
-
K
L
--------
K
D
V
-------
E
K
L
A
E
E
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
F
A
G
----
K
V
R
E
L
A
G
R
L
--------------------------------
7
PsiBlast_PDB
83.74
29%
-109
- C3 -
5AUQ
1
?
A:
[16-220]
---------------------------------------------------------------------------------------------
E
G
V
K
R
I
I
P
V
-
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
---------
E
-
F
--
P
E
E
------
D
------
R
G
-------------
V
V
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
-
Y
-
Y
T
--------
L
R
G
K
E
I
S
D
A
-
L
I
E
L
L
T
--
I
T
---
R
---
W
----------
D
---
E
L
D
Y
L
V
I
D
M
P
P
G
-
L
G
D
-
Q
-
L
L
D
V
-
L
R
F
L
K
R
G
E
--
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
----
E
G
-----
H
K
V
I
G
V
V
E
N
-
M
-
K
L
R
-------
K
D
V
-------
E
K
L
A
E
E
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
F
A
G
----
K
V
R
E
L
A
G
R
L
--------------------------------
6
PsiBlast_PDB
83.64
29%
-111
- C3 -
5AUP
3
?
B:
[16-220]
---------------------------------------------------------------------------------------------
E
G
V
K
R
I
I
P
V
-
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
---------
E
-
F
--
P
E
E
------
D
------
R
G
-------------
V
V
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
-
Y
-
Y
T
E
D
R
P
--
T
P
L
R
G
K
E
I
S
D
A
-
L
I
E
L
L
T
--
I
T
---
R
---
W
----------
D
---
E
L
D
Y
L
V
I
D
M
P
P
G
-
L
G
D
-
Q
-
L
L
D
V
-
L
R
F
L
K
R
G
E
--
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
----
E
G
-----
H
K
V
I
G
V
V
E
N
-
M
-
K
L
--------
K
D
V
-------
E
K
L
A
E
E
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
F
A
G
----
K
V
R
E
L
A
G
R
L
--------------------------------
113
HHSearch
82.61
25%
-96
- C2 -
1G3Q
2
?
A:
[2-236]
------------------------------------------------------------------------------------------------
G
R
I
I
S
I
-
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
G
-------
V
D
D
P
---------
D
V
T
--
L
H
D
------
V
L
A
GEAN
V
E
-----------
D
A
I
Y
M
T
----
Q
F
D
N
V
Y
V
L
P
-
G
-
A
-
V
D
W
E
H
V
L
------
K
--
A
D
P
R
K
-
L
P
E
V
I
K
--
S
L
---
K
--------------
D
---
K
F
D
F
I
L
I
D
C
P
A
G
-
L
Q
L
-
D
-
A
M
S
A
---
M
L
S
G
E
E
--
A
L
L
V
T
N
P
E
I
S
C
L
T
D
T
M
K
V
G
I
-
V
L
K
K
----
A
G
-----
L
A
I
L
G
F
V
L
N
-
R
Y
G
R
S
D
R
D
------
I
-----
P
P
E
A
A
E
D
V
M
E
V
P
L
L
A
V
I
P
E
D
P
A
I
R
E
G
T
L
E
G
I
P
A
V
K
Y
K
P
E
S
----
K
G
A
K
A
F
V
K
L
A
E
E
I
E
K
L
A
------------------------
14
PsiBlast_PDB
79.10
26%
-70
- C3 -
4RZ2
-
?
A:
[28-267]
------------------------------------------------------------------------------------
P
S
P
R
T
----------
I
A
V
-
T
S
G
K
G
G
V
G
K
S
N
V
S
L
N
F
S
L
S
L
S
K
L
G
F
R
V
L
L
L
D
M
D
I
G
M
G
N
I
D
I
L
L
G
-------
E
S
S
S
---------
L
-
A
--
L
A
D
------
W
------
F
S
-----------
A
R
L
-
P
L
----
S
E
L
-
V
K
S
G
P
-
E
-
H
-
L
S
Y
I
A
G
G
T
G
A
A
Q
W
Q
G
-
L
D
T
A
S
-
I
D
R
F
L
T
--
E
L
Q
A
-
V
---
A
----------
S
---
Q
Y
D
Y
L
I
F
D
M
G
A
G
-
A
S
G
-
E
-
R
L
Y
F
-
L
K
S
V
--
D
D
--
V
F
V
V
T
T
P
E
P
T
A
M
T
D
A
---
Y
A
-
M
M
K
Y
----
M
H
A
A
GSE
A
P
F
S
V
I
V
N
R
-
A
G
-----
K
E
R
E
G
Y
E
V
F
E
R
L
K
H
V
T
G
R
F
L
N
K
D
I
A
L
L
G
I
I
P
E
D
R
T
V
A
R
A
V
V
S
Q
T
P
F
V
L
L
D
P
A
A
----
K
A
S
K
A
V
R
Q
M
A
F
R
Y
A
P
R
F
F
A
K
L
R
Q
L
F
L
E
R
-------------
12
PsiBlast_PDB
78.15
26%
-84
- C2 -
1G3Q
2
?
A:
[3-233]
-------------------------------------------------------------------------------------------------
R
I
I
S
I
-
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
G
-------
V
D
D
P
---------
D
-
V
--
T
L
H
------
D
V
L
----
A
G
-----------
E
A
N
V
-------
E
D
A
I
Y
M
T
Q
-
F
-
D
-
N
V
Y
V
L
P
G
A
--
V
D
W
E
--
H
V
L
K
A
-
D
P
R
K
L
P
--
E
V
---
I
---
K
----------
S
L
KD
K
F
D
F
I
L
I
D
C
P
A
G
-
L
-----
Q
L
D
A
-
M
S
A
M
-
L
S
G
E
E
A
L
L
V
T
N
P
E
I
S
C
L
T
D
T
M
K
V
G
I
-
V
L
K
K
----
A
G
-----
L
A
I
L
G
--------
F
V
L
N
R
Y
G
R
S
D
R
D
I
P
P
-
E
A
A
E
D
V
M
E
---
V
P
L
L
A
V
I
P
E
D
P
A
I
R
E
G
T
L
E
G
I
P
A
V
K
Y
K
P
E
S
----
K
G
A
K
A
F
V
K
L
A
E
E
I
E
K
L
A
------------------------
15
PsiBlast_PDB
78.07
25%
-76
- C3 -
4RZ3
2
?
A:
[29-267]
-------------------------------------------------------------------------------------
S
P
R
T
----------
I
A
V
-
T
S
G
K
G
G
V
G
K
S
N
V
S
L
N
F
S
L
S
L
S
K
L
G
F
R
V
L
L
L
D
M
A
I
G
M
G
N
I
D
I
L
L
G
-------
E
S
S
S
---------
L
-
A
--
L
A
D
------
W
------
F
S
-----------
A
R
L
-
P
L
----
S
E
L
-
V
K
S
G
P
-
E
-
H
-
L
S
Y
I
A
G
G
T
GA
A
Q
W
Q
G
-
L
D
T
A
S
-
I
D
R
F
L
T
--
E
L
Q
A
-
V
---
A
----------
S
---
Q
Y
D
Y
L
I
F
D
M
G
A
G
-
A
S
G
-
E
-
R
L
Y
F
-
L
K
S
V
--
D
D
--
V
F
V
V
T
T
P
E
P
T
A
M
T
D
A
---
Y
A
-
M
M
K
Y
----
M
H
A
A
GSE
A
P
F
S
V
I
V
N
R
-
A
G
-----
K
E
R
E
G
Y
E
V
F
E
R
L
K
H
V
T
G
R
F
L
N
K
D
I
A
L
L
G
I
I
P
E
D
R
T
V
A
R
A
V
V
S
Q
T
P
F
V
L
L
D
P
A
A
----
K
A
S
K
A
V
R
Q
M
A
F
R
Y
A
P
--------------------------
118
HHSearch
77.74
23%
-87
- C2 -
1HYQ
-
?
A:
[2-233]
------------------------------------------------------------------------------------------------
V
R
T
I
T
V
-
A
S
G
K
G
G
T
G
K
T
T
I
T
A
N
L
G
V
A
L
A
Q
L
G
H
D
V
T
I
V
D
A
D
I
T
M
A
N
L
E
L
I
L
G
-------
M
E
G
L
---------
P
-
V
T-
L
Q
N
V
L
A
GEA
R
------
I
D
-----------
E
A
I
Y
V
-----
G
P
G
G
V
K
V
V
P
-
A
-
G
-
V
S
L
E
G
L
R
K
--------
A
N
P
E
K
-
L
E
D
V
L
T
--
Q
I
---
M
--------------
E
---
S
T
D
I
L
L
L
D
A
P
A
G
-
L
E
R
-
S
-
A
V
I
A
-
I
A
--
A
A
Q
E
--
L
L
L
V
V
N
P
E
I
S
S
I
T
D
G
L
K
T
K
I
-
V
A
E
R
----
L
G
-----
T
K
V
L
G
V
V
V
N
-
R
I
T
T
L
G
I
E
-----
M
------
A
K
N
E
I
E
A
I
L
E
A
K
V
I
G
L
I
P
E
D
P
E
V
R
R
A
A
A
Y
G
K
P
V
V
L
R
S
P
N
S
----
P
A
A
R
A
I
V
E
L
A
N
Y
I
A
---------------------------
11
PsiBlast_PDB
77.08
26%
-79
- C2 -
1ION
2
?
A:
[3-233]
-------------------------------------------------------------------------------------------------
R
I
I
S
I
-
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
E
M
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
G
-------
V
D
D
V
---------
N
-
I
--
T
L
H
------
D
V
L
----
A
G
-----------
D
A
K
L
E
D
----
A
I
Y
M
T
Q
F
E
N
-
V
-
Y
-
I
L
---
P
G
A
--
V
D
W
E
--
H
V
I
K
A
-
D
P
R
K
L
P
--
E
V
---
I
K
S
L
K
----------
G
---
K
Y
D
F
I
L
I
D
C
P
A
G
-
L
-----
Q
L
R
--
A
M
S
A
M
L
S
G
E
E
A
I
L
V
T
N
P
E
I
S
C
L
T
D
T
M
K
V
G
M
-
V
L
K
K
----
A
G
-----
L
A
I
L
G
F
I
L
N
-------
R
Y
G
R
S
E
R
D
I
P
P
E
-
A
A
Q
----
D
V
M
D
V
P
L
L
A
V
I
P
E
D
P
V
I
R
E
G
T
L
E
G
I
P
A
V
K
Y
K
P
E
S
----
K
G
A
Q
A
F
I
K
L
A
E
E
V
D
K
L
A
G
I
K
A
K
I
------------------
13
PsiBlast_PDB
76.90
26%
-88
- C2 -
1G3R
2
?
A:
[3-233]
-------------------------------------------------------------------------------------------------
R
I
I
S
I
-
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
G
-------
V
D
D
P
---------
D
-
V
--
T
L
H
------
D
V
L
----
A
G
-----------
E
A
N
V
-------
E
D
A
I
Y
M
T
Q
-
F
-
D
-
N
V
Y
V
L
P
G
A
--
V
D
W
E
--
H
V
L
K
A
-
D
P
R
K
L
P
--
E
V
---
I
---
K
----------
S
L
KD
K
F
D
F
I
L
I
D
C
P
A
G
-
L
-----
Q
L
D
A
-
M
S
A
M
-
L
S
G
E
E
A
L
L
V
T
N
P
E
I
S
C
L
T
D
T
M
K
V
G
I
-
V
L
K
K
----
A
G
-----
L
A
I
L
G
--------
F
V
L
N
R
Y
G
R
S
D
R
D
I
P
P
-
E
A
A
E
D
V
M
E
---
V
P
L
L
A
V
I
P
E
D
P
A
I
R
E
G
T
L
E
G
I
P
A
V
K
Y
K
P
E
S
----
K
G
A
K
A
F
V
K
L
A
E
E
I
E
K
L
A
------------------------
9
PsiBlast_PDB
76.82
27%
-87
- C2 -
1HYQ
-
?
A:
[3-229]
-------------------------------------------------------------------------------------------------
R
T
I
T
V
-
A
S
G
K
G
G
T
G
K
T
T
I
T
A
N
L
G
V
A
L
A
Q
L
G
H
D
V
T
I
V
D
A
D
I
T
M
A
N
L
E
L
I
L
G
MEGLPVT
L
Q
N
V
L
A
GEARIDE
A
-
I
--
Y
V
G
------
P
------
G
G
-----------
V
K
V
V
P
-------
A
G
V
S
L
-----------
E
G
-----------
L
R
K
A
-
N
P
E
K
L
E
--
D
V
L
T
Q
I
---
M
----------
E
---
S
T
D
I
L
L
L
D
A
P
A
G
L
E
R
S
-
A
-
V
I
A
I
-
A
A
A
Q
E
L
-----
L
L
V
V
N
P
E
I
S
S
I
T
D
G
L
K
T
K
I
-
V
A
E
R
----
L
G
-----
T
K
V
L
G
V
V
V
N
R
I
T
T
L
G
I
E
M
A
K
---------
N
E
I
E
A
I
L
E
A
---
K
V
I
G
L
I
P
E
D
P
E
V
R
R
A
A
A
Y
G
K
P
V
V
L
R
S
P
N
S
----
P
A
A
R
A
I
V
E
L
A
N
Y
I
A
---------------------------
8
PsiBlast_PDB
76.04
27%
-81
* C3 *
4V03
2
?
A:
[3-234]
-------------------------------------------------------------------------------------------------
E
V
I
V
I
-
T
S
G
K
G
G
V
G
K
T
T
L
T
A
N
I
G
T
A
L
A
K
L
G
K
K
V
L
L
I
D
A
D
---
R
N
L
D
M
I
L
G
-------
L
E
N
R
---------
I
-
V
YD
I
L
D
------
V
------
L
E
-----------
G
R
V
P
Y
E
----
K
A
------------
L
V
K
D
K
R
G
L
--
S
L
W
L
L
P
---------
V
I
D
--
I
E
---
K
---
W
N
K
T
V
E
E
I
K
N
S
G
---
N
Y
D
Y
I
L
V
D
S
P
A
G
-
I
E
K
-
G
F
Q
I
A
V
-
S
---
P
A
D
K
--
A
L
I
V
V
N
P
E
V
S
S
I
R
D
A
D
R
V
I
G
-
L
L
E
S
----
M
D
-----
K
R
N
Y
K
V
I
V
N
---
R
I
K
W
E
M
V
K
R
G
A
M
L
-----
S
V
E
D
I
V
D
I
L
K
A
E
I
I
G
I
I
P
E
E
P
K
L
V
D
F
T
N
R
G
E
P
I
V
L
D
E
K
F
P
----
A
S
Q
A
I
I
D
T
A
R
R
L
M
G
E
S
I
P
L
K
R
--------------------
10
PsiBlast_PDB
75.77
26%
-78
- C3 -
4V02
2
?
A:
[3-234]
-------------------------------------------------------------------------------------------------
E
V
I
V
I
-
T
S
G
K
G
G
V
G
K
T
T
L
T
A
N
I
G
T
A
L
A
K
L
G
K
K
V
L
L
I
D
A
A
I
G
L
R
N
L
D
M
I
L
G
-------
L
E
N
R
---------
I
-
V
YD
I
L
D
------
V
------
L
E
-----------
G
R
V
P
Y
E
----
K
A
------------
L
V
K
D
K
R
G
L
--
S
L
W
L
L
P
A
-------
D
V
I
D
--
I
E
---
K
---
W
N
K
T
V
E
E
I
K
N
S
G
---
N
Y
D
Y
I
L
V
D
S
P
A
G
-
I
E
K
-
G
F
Q
I
A
V
-
S
---
P
A
D
K
--
A
L
I
V
V
N
P
E
V
S
S
I
R
D
A
D
R
V
I
G
-
L
L
E
S
----
M
D
-----
K
R
N
Y
K
V
I
V
N
---
R
I
K
W
E
M
V
K
R
G
A
M
L
-----
S
V
E
D
I
V
D
I
L
K
A
E
I
I
G
I
I
P
E
E
P
K
L
V
D
F
T
N
R
G
E
P
I
V
L
D
E
K
F
P
----
A
S
Q
A
I
I
D
T
A
R
R
L
M
G
E
S
I
P
L
K
R
Y
G
E
-----------------
120
HHSearch
73.06
19%
-91
- C2 -
2YNM
12
CHLL_PROMA
A:
[34-288]
------------------------------------------------------------------------------------------------
A
L
V
I
A
V
--
Y
G
K
G
G
I
G
K
S
T
T
S
S
N
L
S
A
A
F
S
K
L
G
K
K
V
L
Q
I
G
C
D
P
K
H
D
S
T
F
T
L
T
H
--------
K
M
V
---------
P
-
T
--
V
I
D
------
I
------
L
E
E
V
DFHSEELRP
Q
D
F
M
F
E
----
G
F
N
G
V
Q
C
V
E
-
S
-
G
-
G
P
P
A
G
T
G
C
--
G
G
----
Y
V
T
G
Q
-
T
V
K
L
L
K
E
H
H
L
---
L
--------------
E
---
D
T
D
V
V
I
F
D
V
L
G
D
-
V
V
C
G
G
-
F
A
A
P
-
L
Q
H
--
A
N
Y
--
C
L
I
V
T
A
N
D
F
D
S
I
F
A
M
N
R
I
V
A
-
A
I
N
A
K
A
K
N
Y
K
-----
V
R
L
G
G
V
I
A
N
-
R
S
A
E
L
D
--------------
Q
I
E
K
F
N
E
K
T
G
L
K
T
M
A
H
F
R
N
V
D
A
I
R
R
S
R
L
K
K
C
T
I
F
E
M
D
P
E
E
EG
V
L
E
V
Q
N
E
Y
L
S
L
A
K
K
M
I
D
N
V
E
P
L
E
A
E
P
L
K
D
R
E
I
F
D
L
L
G
F
-----