@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0200: (2015-12-13 )
MENHLHADTNTDDKSTKIVRLFGLIGGALIALIIYYALDAQMPHIVEEIPKLSSLNYKAMPVVAGVAVLMGIWWMTEAIDLPATALLPLVLFNVFSVDQFSSVSASYASPIIFLFMGGFILALSMQKWNLHTRIALSIILLVGTSPRRLILGFMIATGFLSMWVSNTATAVMMFPVGMSVLQLVAKLVGKENASNAFYQKEEITKAHGGIMSNIVHKGKDIAQVIQEKTTIYRTNFSICLMLGIAYSASIGSLGTLIGTPPNALLAGYMKTAFNIEIDFAQWMVFGTPLAFIMLILAWLLLTYVIFPLKIKEIPGGKEVVKSELKKLRRLSQAEISVGVIFILASLGWIFLDTILKSWGIKIDKIDSVIAMGVSALLFILPANHQGDRLIDWGVAKKLPWDVLLLFGGGLALSAQFSKTGLSLWIGHLVSGFSHLPILFIIVMVTLMVIFLTEITSNTATAAAFLPVIGGVAMGMGYESHQSLLLTIPVALSATCAFMLPVATPPNAIAYGSGYVKITDMIKAGLWLNLVGVVLISAFSYCLVSLIFN
Atome Classification :
(10 SA)
.........10...----.....20....-----....30.....-----...40........50........60.----........--70--------------------.........80........90.....---...100...----------------------------------------------....110.......120.......130.......140.......150.......160.......170....----...180.......190.......200.......210.....-----..220.......230.......240........250---------------------.........260...--....270.......280.......290.......300-.......310.-----......320.......330.......340.......350......-.360.......370.......380.......390.-......400.......410.......420.....-----..430-.....----------..440.......450....---...460.......470....-------------------------...480.......490-----........500.......510...----------....520.......530.......540......------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MENHLHADTNTDDK----ST
K
I
V
R
L
F
G
L
I
-----
G
G
A
L
I
A
L
I
I
Y
Y
-----ALDAQM
P
H
I
V
E
E
I
P
K
L
SSLNYKA
M
-
P
----
V
V
A
G
V
A
V
L
--
M
---------------------
G
I
W
W
M
T
EAIDL
P
A
T
A
L
L
P
L
V
L
F
N
V
F
S
---
V
D
Q
F
S
S
V
S
A
----------------------------------------------SYASP
I
I
F
L
F
MGG
F
I
L
A
L
S
M
QKWN
L
H
T
R
I
A
L
S
I
I
L
L
VGTSP
R
R
L
I
L
G
F
M
I
A
T
G
F
L
S
M
W
V
SNT
A
T
A
V
M
M
FPV----
G
M
S
V
L
Q
L
V
A
K
L
VGKENASNA
F
Y
Q
K
E
E
I
T
K
AH
G
G
I
M
S
N
I
V
HK-----G
K
D
I
A
Q
V
I
Q
EK
T
T
I
Y
RTN
F
S
I
C
L
M
-LG
I
A
YSASI-----------------------GSL
G
T
LIGT
P
P
N
A
L
L
--
A
G
Y
M
K
T
A
F
N
I
E
I
D
F
A
Q
W
M
VFG
T
P
L
A
F
I
M
L
I
L
A
W
L
L
L
T
-
Y
V
IF
P
L
K
I
KEI-----PG
G
K
E
V
V
K
S
E
L
K
K
L
R
R
L
S
Q
A
E
I
S
V
G
V
I
F
I
L
A
S
L
G
W
I
F
L
D
T
I
L
K
S
W-G
I
K
I
D
K
I
D
S
V
I
A
M
G
V
S
A
L
L
F
I
L
PANHQGD
R
L
I
D
W
G
-
V
AKKLP
W
D
V
L
L
L
FGG
G
L
A
L
S
A
QFSKT
G
L
S
L
W
I
G
H
-----
L
V
SGF-SH
L
P
I
----------
L
F
I
I
V
M
V
T
L
M
V
I
F
L
T
E
ITS---NTA
T
A
A
A
F
L
P
V
I
G
G
V
A
MGMG-------------------------YESH
Q
S
L
L
L
T
I
P
V
A
L
------SA
T
C
A
F
M
L
PVATPPN
A
I
AYGS
G
Y
V
----------
K
I
T
D
M
I
KA
G
L
W
L
N
L
V
G
V
V
L
I
S
A
F
S
Y
C
L
V
S
L
IFN------------------------------------------------------------------------
1
PsiBlast_PDB
85.64
31%
-159
- C4 -
4F35
2
?
D:
[23-442]
----------------------------------------------------------------------
Y
H
F
L
-
P
FEH
N
V
V
L
G
I
S
M
L
A
F
I
---------------------
A
V
L
W
L
T
E
A
L
H
V
T
V
T
A
I
L
V
P
V
M
A
V
F
F
G
---
I
F
E
T
Q
A
A
L
N
----------------------------------------------
N
F
A
N
S
I
I
F
L
F
L
G
G
F
A
L
A
A
A
M
H
H
Q
G
L
D
K
V
I
A
D
K
V
L
A
M
A
Q
G
K
M
S
V
A
V
F
M
L
F
G
V
T
A
L
L
S
M
W
I
S
N
T
A
T
A
A
M
M
-----------
L
P
L
V
L
G
V
L
S
K
V
D
A
D
K
-----------------------------------
Q
R
S
T
Y
V
F
-------
V
L
-
L
G
V
A
Y
S
A
S
I
-----------------------
G
G
I
A
T
L
V
G
S
P
P
N
A
I
A
--
A
A
------
E
V
G
L
S
F
T
D
W
M
K
F
G
L
P
T
A
M
M
M
L
P
M
A
I
A
I
L
Y
-
F
L
L
-------------------
V
N
W
D
K
G
K
V
V
T
L
G
--------
I
F
G
L
T
V
F
L
W
I
F
S
S
P
I
N
A
A
L
-
G
-
G
F
K
S
F
D
T
L
V
A
L
G
--
A
I
L
M
L
S
F
A
-----
R
V
V
H
W
K
E
I
Q
K
T
A
D
W
G
V
L
L
L
F
G
G
G
L
C
L
S
N
V
L
K
Q
T
G
T
S
V
F
L
A
N
-----
A
L
S
D
M
V
S
H
M
G
I
----------
F
V
V
I
L
V
V
A
T
F
V
V
F
L
T
E
F
A
S
---
N
T
A
S
A
A
L
L
I
P
V
F
A
T
V
A
E
A
F
G
-------------------------
M
S
P
---
V
L
L
S
V
L
I
A
V
------
A
A
S
C
A
F
M
L
P
V
A
T
P
P
N
A
I
V
F
A
S
G
H
I
----------
K
Q
S
E
M
M
R
V
G
L
Y
L
N
I
A
C
I
G
L
L
T
A
I
A
M
L
F
W
Q
----------------------------------------------------------------------------
12
Fugue
64.61
17%
-136
- C3 -
4J5T
4
CWH41_YEAST
A:
[1-811]
A
E
F
M
E
E
Y
Q
K
F
T
N
E
S
L
LWA
P
Y
R
S
N
C
Y
F
G
M
R
P
R
YVH
E
S
P
L
I
M
G
I
M
W
F
N
SLSQ
D
G
L
H
S
L
R
H
F
A
T
P
Q
D
K
L
Q
K
Y
G
W
E
V
Y
D
P
----
R
I
G
G
K
E
V
F
--
I
D
EKNNLN
L
T
V
Y
F
V
K
S
KNGE
N
W
S
V
R
V
Q
G
E
P
L
D
P
K
R
P
S
T
A
S
V
V
L
Y
F
S
Q
N
GGE
I
D
G
K
S
S
L
A
M
IGHDGPN
D
M
K
F
F
G
Y
S
KEL
G
E
Y
H
L
T
V
K
D
N
F
G
H
Y
F
KNPEYETMEVAPG
S
D
C
S
K
T
S
H
L
S
L
Q
I
P
D
K
E
V
W
K
A
R
D
V
F
Q
S
L
V
S
D
S
I
R
D
I
L
-
E
R
P
A
D
L
I
P
S
V
L
T
I
R
N
L
Y
N
F
N
P
G
N
F
H
Y
I
Q
K
T
F
D
L
TKKD
G
F
Q
F
D
I
T
Y
N
K
L
G
T
T
Q
S
I
S
T
R
E
Q
V
T
E
L
I
T
W
S
L
N
E
I
N
A
R
F
D
K
Q
F
S
F
G
E
G
P
D
S
I
E
S
V
E
V
K
R
R
F
A
L
E
T
L
S
N
L
L
G
G
I
G
Y
F
Y
G
N
Q
L
I
D
RETEFDESQFTEIKLLN
A
K
E
E
G
P
F
E
L
F
T
S
V
P
S
R
G
F
F
PR
G
F
Y
W
D
E
G
F
H
L
----
L
Q
I
M
E
Y
D
F
D
L
A
F
E
I
L
-
A
S
W
F
E
M
I
-
E
D
D
S
G
W
I
A
R
E
I
-----
I
L
G
N
E
A
R
S
K
V
P
Q
E
F
Q
V
Q
N
P
N
I
A
N
P
P
T
L
L
L
A
F
S
E
M
L
S
R
A
I
E
N
I
G
D
F
M
T
N
N
L
E
A
N
P
G
L
L
T
E
Y
A
K
K
I
Y
P
K
L
L
K
H
Y
N
W
F
R
K
S
Q
T
G
-
L
I
D
--
E
Y
E
E
I
L
E
D
E
G
---
I
W
D
K
I
H
K
N
E
V
Y
R
W
V
G
R
TFTHC
L
P
S
G
M
-
D
D
Y
P
R
AQPPDVAELN
V
D
A
L
A
W
V
G
V
M
T
R
S
M
K
Q
I
A
H
V
L
K
L
T
Q
D
E
Q
R
Y
A
Q
I
E
Q
E
V
V
E
N
L
D
L
LHWSENDN
C
Y
C
D
I
S
I
DPEDDE
I
R
E
F
V
C
H
E
G
Y
V
S
V
L
P
F
A
L
KLIPKN
S
P
K
L
E
K
V
V
A
L
M
S
D
P
E
K
I
F
S
D
Y
G
L
L
SLSRQDDYFG
K
D
E
N
Y
W
R
G
P
I
W
M
N
I
N
-
Y
L
C
L
D
A
M
R
Y
Y
Y
P
E
V
I
L
D
VAGEAS
N
A
K
K
L
Y
Q
S
L
K
I
N
L
S
N
N
I
Y
K
V
W
E
EQGYCYE
N
Y
S
PIDGHGTGAEHFTGWTAL
V
V
N
I
L
G
R
F
RS
H
H
H
H
HH
11
Fugue
35.81
15%
641
- C4 -
2R28
1
D:
[5-23]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
V
I
R
N
K
I
R
A
I
G
K
M
A
R
V
F
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
Fugue
35.03
24%
-62
- C4 -
4RS8
-
?
A:
[1-84]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
I
F
L
T
P
R
A
Y
I
--
I
V
H
L
L
K
V
G
K
A
K
A
S
E
I
S
E
N
T
-
Q
I
P
Y
Q
T
V
I
Q
N
I
R
W
L
L
A
E
G
Y
V
V
K
E
Q
K
G
E
E
I
Y
Y
K
L
T
D
K
G
K
Q
M
A
T
A
E
L
E
K
I
R
K
L
V
E
V
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
34.21
12%
488
* C4 *
2JZI
-
B:
[1-24]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
K
E
V
I
R
N
K
I
R
A
I
G
K
M
A
R
V
F
S
V
L
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
32.43
44%
1684
- C1 -
2KWH
-
RBP1_HUMAN
A:
[410-418]
--
N
S
L
H
R
D
L
Q
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
Fugue
23.95
13%
162
- C4 -
4XO2
-
GNSA_ECOLI
A:
[1-60]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
I
E
E
L
K
K
Q
A
E
T
E
I
A
D
F
I
A
Q
K
I
A
E
L
N
K
N
T
G
K
E
V
S
E
I
R
F
T
-----
A
R
E
K
M
T
G
L
E
S
Y
D
V
K
I
K
I
M
L
E
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
Fugue
23.35
26%
262
- C4 -
1KIL
-
CPLX1_RAT
E:
[9-49]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
E
E
E
R
Q
E
A
L
R
Q
A
E
E
E
R
K
A
K
---
Y
A
K
M
E
A
E
-----
R
E
V
M
R
Q
G
I
R
D
K
Y
G
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
Fugue
19.84
31%
523
- C4 -
2JOS
-
A:
[1-22]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
F
H
H
I
F
R
G
I
V
H
V
-----
G
K
T
I
H
R
L
V
T
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
17.70
22%
4081
- C2 -
2BRQ
1
ITB7_HUMAN
C:
[9-15]
---
P
L
Y
K
S
A
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------