@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0268: (2015-12-14 )
MQEILIPLKEKSYKVFLGELPEIKLKQKALIISDSIVAGLHLPYLLERLNALEVRVCVIESGEKYKNFHSLERILNNAFEMQLNRHSLMIALGGGVISDMVGFASSIYFRGIDFINIPTTLLAQVDASVGGKTGINTPYGKNLIGSFHQPKAVYMDLAFLKTLEKREFQAGVAEIIKMAVCFDKNLVERLETKDLKDCLEEVIFQSVNIKAQVVVQDEKERNIRAGLNYGHTFGMLIENETNYERFLHGEAIAIGMRMANDLALSLGMLTLKEYERIENLLKKFDLIFNYQITDIQKFYERLFLDKKSENQTLKFILPKGVGAFEIASHIPKETILKVLEKWH
Atome Classification :
(44 SA)
------.........10.......----.-------20..-------..--.-.----...30........40........50-.--------..------.....---------.60-.........70........80-..--.......90........100.......110.......120.......130.......140.......150.......160.......170.......180...----....190------.----------------.-------..--------------------..--------..200.......210.......220.......230.......240.......250.......260.......270.......280---....-...290-.-----------....-----------..300---------........-----.310.......320.-...--.-----..330.......340.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------MQE
I
L
IPLKEK
S
Y
K
V
F
LG----E-------L-PE-------
I
K
--
L
-
K
----
Q
K
A
L
I
IS
D
S
I
V
AGL
H
L
P
Y
L
L
E
R
L
N
--A--------
L
E
------
V
R
V
C
V
---------IE--S
G
E
K
Y
K
N
F
H
S
L
E
R
I
L
N
N
A
F
E
--
M
Q--LNR
H
S
L
M
I
A
LG
G
G
V
I
S
D
M
V
G
F
A
S
S
I
YFRG
I
D
FINI
P
T
T
L
L
A
Q
V
D
ASVGGKTGINTPYG
K
N
L
I
GSFHQP
K
A
V
Y
M
D
L
A
F
L
K
T
L
E
K
R
E
F
Q
A
G
V
A
E
I
I
K
M
A
V
CF
D
K
N
----
L
V
E
R
L
E
-------
T
----------------
K
-------
D
L
--------------------
K
D
--------
C
L
E
E
V
I
F
QSVN
I
K
A
Q
V
V
V
QDEKERNIRAGLNYG
H
T
F
G
M
L
IENET
N
Y
E
R
F
LHG
E
A
I
A
I
G
M
R
M
A
N
D
L
A
L
S
L
G
M
L
T
L
K
E
Y
E
R
I
E
N
L
L
K
---
K
F
D
L
-
I
F
N
Y
QI-
T
-----------
D
I
Q
K
-----------
F
Y
E
-----------
R
LFLDKKS-----EN
Q
T
L
K
F
I
LPKGV
G
A
-
F
E
I
--
A
-----
S
HI
P
K
E
T
I
L
K
V
L
E
KWH
54
HHSearch
97.98
40%
-113
- C4 -
3OKF
9
AROB_VIBCH
A:
[31-387]
-------
E
R
I
T
V
N
L
G
E
R
S
Y
P
I
S
I
G
----
A
-------
G
L
F
A
NPAL---
L
S
LS
A
-
K
----
Q
K
V
V
I
V
T
N
H
T
V
A
P
L
Y
A
P
A
I
I
S
L
L
D
H
I
G
--------
C
Q
------
H
A
L
L
E
---------
L
P
--
D
G
E
Q
Y
K
T
L
E
T
F
N
T
V
M
S
F
L
L
E
--
H
N
--
Y
S
R
D
V
V
V
I
A
L
G
G
G
V
I
G
D
L
V
G
F
A
A
A
C
Y
Q
R
G
V
D
F
I
Q
I
P
T
T
L
L
S
Q
V
D
S
S
V
G
G
K
T
A
V
N
H
P
L
G
K
N
M
I
G
A
F
Y
Q
P
K
A
V
V
I
D
T
D
C
L
T
T
L
P
A
R
E
F
A
A
G
M
A
E
V
I
K
Y
G
I
I
Y
D
S
A
----
F
F
D
W
L
E
-------
A
----------------
Q
-------
M
E
A
L
Y
A
LD--------------
E
Q
--------
A
L
T
Y
A
I
A
R
C
C
Q
I
K
A
E
V
V
A
Q
D
E
K
--
G
I
R
A
L
L
N
L
G
H
T
F
G
H
A
I
E
A
H
M
G
Y
G
N
W
L
H
G
E
A
V
S
A
G
T
V
M
A
A
K
T
A
Q
L
Q
G
L
I
D
A
S
Q
F
E
R
I
L
A
I
L
K
---
K
A
H
L
-
P
V
R
T
P
E
N
M
-----------
T
F
A
D
-----------
F
M
Q
-----------
H
M
M
R
D
K
K
V
-----
L
A
G
E
L
R
L
V
L
P
T
S
I
G
T
-
S
A
V
--
V
-----
K
G
V
P
E
A
V
I
A
Q
A
I
E
Y
C
R
1
PsiBlast_PDB
97.03
39%
-113
- C4 -
3OKF
9
AROB_VIBCH
A:
[30-385]
------
M
E
R
I
T
V
N
L
G
E
R
S
Y
P
I
S
I
G
----
A
GLFANPA
L
-
L
S
-------
L
S
--
A
-
K
----
Q
K
V
V
I
V
T
N
H
T
V
A
P
L
Y
A
P
A
I
I
S
L
L
D
--
H
--------
I
G
------
C
Q
H
A
L
---------
L
E
L
P
D
G
E
Q
Y
K
T
L
E
T
F
N
T
V
M
S
F
L
L
E
--
H
N
--
Y
S
R
D
V
V
V
I
A
L
G
G
G
V
I
G
D
L
V
G
F
A
A
A
C
Y
Q
R
G
V
D
F
I
Q
I
P
T
T
L
L
S
Q
V
D
S
S
V
G
G
K
T
A
V
N
H
P
L
G
K
N
M
I
G
A
F
Y
Q
P
K
A
V
V
I
D
T
D
C
L
T
T
L
P
A
R
E
F
A
A
G
M
A
E
V
I
K
Y
G
I
I
Y
D
S
A
----
F
F
D
W
L
E
-------
A
----------------
Q
M
E
A
L
Y
A
L
D
---------------------
E
Q
--------
A
L
T
Y
A
I
A
R
C
C
Q
I
K
A
E
V
V
A
Q
D
E
K
--
G
I
R
A
L
L
N
L
G
H
T
F
G
H
A
I
E
A
H
M
G
Y
G
N
W
L
H
G
E
A
V
S
A
G
T
V
M
A
A
K
T
A
Q
L
Q
G
L
I
D
A
S
Q
F
E
R
I
L
A
I
L
K
---
K
A
H
L
P
V
R
T
P
E
N
-
M
-----------
T
F
A
D
-----------
F
M
Q
-----------
H
M
M
R
D
K
K
V
-----
L
A
G
E
L
R
L
V
L
P
T
S
I
G
T
-
S
A
V
--
V
-----
K
G
V
P
E
A
V
I
A
Q
A
I
E
Y
C
R
21
PsiBlast_CBE
94.50
39%
-117
- C4 -
3OKF
6
AROB_VIBCH
B:
[30-385]
------
M
E
R
I
T
V
N
L
G
E
R
S
Y
P
I
S
I
G
----
A
GLFANPA
L
-
L
S
-------
L
S
--
A
-
K
----
Q
K
V
V
I
V
T
N
H
T
V
A
P
L
Y
A
P
A
I
I
S
L
L
D
--
H
--------
I
G
------
C
Q
H
A
L
---------
L
E
L
P
D
G
E
Q
Y
K
T
L
E
T
F
N
T
V
M
S
F
L
L
E
--
H
N
--
Y
S
R
D
V
V
V
I
A
L
G
G
G
V
I
G
D
L
V
G
F
A
A
A
C
Y
Q
R
G
V
D
F
I
Q
I
P
T
T
L
L
S
Q
V
D
S
S
V
G
G
K
T
A
V
N
H
P
L
G
K
N
M
I
G
A
F
Y
Q
P
K
A
V
V
I
D
T
D
C
L
T
T
L
P
A
R
E
F
A
A
G
M
A
E
V
I
K
Y
G
I
I
Y
D
S
A
----
F
F
D
W
L
E
-------
A
----------------
Q
M
E
A
L
Y
A
L
D
---------------------
E
Q
--------
A
L
T
Y
A
I
A
R
C
C
Q
I
K
A
E
V
V
A
Q
D
E
K
E
S
G
I
R
A
L
L
N
L
G
H
T
F
G
H
A
I
E
A
H
M
G
Y
G
N
W
L
H
G
E
A
V
S
A
G
T
V
M
A
A
K
T
A
Q
L
Q
G
L
I
D
A
S
Q
F
E
R
I
L
A
I
L
K
---
K
A
H
L
P
V
R
T
P
E
N
-
M
-----------
T
F
A
D
-----------
F
M
Q
-----------
H
M
M
R
---------------
L
V
L
P
T
S
I
G
T
-
S
A
V
--
V
-----
K
G
V
P
E
A
V
I
A
Q
A
I
E
Y
C
R
57
HHSearch
85.02
32%
-106
* C4 *
3QBE
3
AROB_MYCTU
A:
[19-365]
-------------
A
V
D
P
P
Y
P
V
V
I
G
----
T
-------
G
L
L
D
E
L
E
D
L
--
L
A
--
D
-
R
----
H
K
V
A
V
V
H
Q
P
G
L
A
E
-
T
A
E
E
I
R
K
R
L
A
G
K
G
--------
V
D
------
A
H
R
I
E
---------
I
P
--
D
A
E
A
G
K
D
L
P
V
V
G
F
I
W
E
V
L
G
R
--
I
G
--
I
G
R
K
D
A
L
V
S
L
G
G
G
A
A
T
D
V
A
G
F
A
A
A
T
W
L
R
G
V
S
I
V
H
L
P
T
T
L
L
G
M
V
D
A
A
V
G
G
K
T
G
I
N
T
D
A
G
K
N
L
V
G
A
F
H
Q
P
L
A
V
L
V
D
L
A
T
L
Q
T
L
P
R
D
E
M
I
C
G
M
A
E
V
V
K
A
G
F
I
A
D
P
V
----
I
L
D
L
I
E
-------
A
----------------
D
-------
P
Q
A
A
L
DPA--------------
G
D
--------
V
L
P
E
L
I
R
R
A
I
T
V
K
A
E
V
V
A
A
----
S
E
L
R
E
I
L
N
Y
G
H
T
L
G
H
A
I
E
R
R
E
R
Y
-
R
W
R
H
G
A
A
V
S
V
G
L
V
F
A
A
E
L
A
R
L
A
G
R
L
D
D
A
T
A
Q
R
H
R
T
I
L
S
---
S
L
G
L
-
P
V
S
Y
D
P
-
D
-----------
A
L
P
Q
-----------
L
L
E
-----------
I
M
A
G
D
K
K
T
-----
R
A
G
V
L
R
F
V
V
L
D
G
L
A
K
-
P
G
R
--
M
-----
V
G
P
D
P
G
L
L
V
T
A
Y
A
G
V
C
43
Fugue
82.85
34%
-98
- C4 -
1DQS
5
ARO1_EMENI
A:
[4-391]
P
T
K
I
S
I
L
G
R
E
S
I
I
A
D
F
G
L
W
R
N
Y
V
A
----
K
-------
D
-
L
I
-------
S
D
--
C
-
S
S---
T
T
Y
V
L
V
T
D
T
N
I
G
S
I
Y
T
P
S
F
E
E
A
F
R
--
K
R
A
A
EITP
S
P
R
------
L
L
I
Y
N
---------
R
P
--
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
QN
P
P
--
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
----
E
F
T
A
L
E
-------
E
N
A
E
T
I
L
K
A
V
R
RRF---
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
P
-
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
L
TAGKHCS
V
D
Q
L
M
F
-----------
N
M
A
L
D
K
K
N
-----
D
G
P
K
K
K
I
V
L
L
S
A
I
G
T
-
P
Y
E
T
R
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
----
22
PsiBlast_CBE
81.97
38%
-98
- C4 -
3ZOK
9
DHQS_ACTCH
D:
[19-352]
-----------
V
D
L
G
D
R
S
Y
P
I
Y
I
G
SGLL
D
-------
Q
-
P
D
-------
L
L
--
Q
-
R
HVHG
K
R
V
L
V
V
T
N
S
T
V
A
P
I
Y
L
D
K
V
V
G
A
L
T
--
N
ENPN----
V
S
------
V
E
S
V
I
---------
L
P
--
D
G
E
K
Y
K
N
M
D
T
L
M
K
V
F
D
K
A
I
E
--
S
R
--
L
D
R
R
C
T
F
V
A
L
G
G
G
V
I
G
D
M
C
G
Y
A
A
A
S
F
L
R
G
V
N
F
I
Q
I
P
T
T
V
M
A
Q
V
D
S
S
V
G
G
K
T
G
I
N
H
R
L
G
K
N
L
I
G
A
F
Y
Q
P
Q
C
V
L
I
D
T
D
T
L
N
T
L
P
D
R
E
L
A
S
G
L
A
E
V
V
K
Y
G
L
I
R
D
A
N
----
F
F
E
W
Q
E
KNMPALM
A
----------------
R
-------
D
---------------------
P
S
--------
A
L
A
Y
A
I
K
R
S
C
E
N
K
A
E
V
V
S
L
D
E
K
E
S
G
L
R
A
T
L
N
L
G
H
T
F
G
H
A
I
E
T
G
F
G
Y
G
Q
W
L
H
G
E
A
V
A
A
G
M
V
M
A
V
D
M
S
Y
R
L
G
W
I
D
E
S
I
V
N
R
A
H
N
I
L
Q
---
Q
A
K
L
P
T
A
P
P
E
T
-
M
-----------
T
V
E
M
-----------
F
K
S
-----------
V
M
A
V
D
K
K
V
-----
A
D
G
L
L
R
L
I
L
L
K
G
P
L
G
-
N
C
V
--
F
-----
T
G
D
Y
D
R
K
A
L
D
E
T
L
H
A
F
2
PsiBlast_PDB
81.78
38%
-94
- C4 -
3ZOK
9
DHQS_ACTCH
A:
[19-352]
-----------
V
D
L
G
D
R
S
Y
P
I
Y
I
G
S
GLL
D
-------
Q
-
P
D
-------
L
L
--
Q
-
R
H
VHG
K
R
V
L
V
V
T
N
S
T
V
A
P
I
Y
L
D
K
V
V
G
A
L
T
--
N
ENPN----
V
S
------
V
E
S
V
I
---------
L
P
--
D
G
E
K
Y
K
N
M
D
T
L
M
K
V
F
D
K
A
I
E
--
S
R
--
L
D
R
R
C
T
F
V
A
L
G
G
G
V
I
G
D
M
C
G
Y
A
A
A
S
F
L
R
G
V
N
F
I
Q
I
P
T
T
V
M
A
Q
V
D
S
S
V
G
G
K
T
G
I
N
H
R
L
G
K
N
L
I
G
A
F
Y
Q
P
Q
C
V
L
I
D
T
D
T
L
N
T
L
P
D
R
E
L
A
S
G
L
A
E
V
V
K
Y
G
L
I
R
D
A
N
----
F
F
E
W
Q
E
K
N
M
P
A
L
M
A
----------------
R
-------
D
---------------------
P
S
--------
A
L
A
Y
A
I
K
R
S
C
E
N
K
A
E
V
V
S
L
D
E
K
E
S
G
L
R
A
T
L
N
L
G
H
T
F
G
H
A
I
E
T
G
F
G
Y
G
Q
W
L
H
G
E
A
V
A
A
G
M
V
M
A
V
D
M
S
Y
R
L
G
W
I
D
E
S
I
V
N
R
A
H
N
I
L
Q
---
Q
A
K
L
P
T
A
P
P
E
T
-
M
-----------
T
V
E
M
-----------
F
K
S
-----------
V
M
A
V
D
K
K
V
-----
A
D
G
L
L
R
L
I
L
L
K
G
P
L
G
-
N
C
V
--
F
-----
T
G
D
Y
D
R
K
A
L
D
E
T
L
H
A
F
58
HHSearch
81.30
35%
-107
- C4 -
1SG6
2
ARO1_EMENI
A:
[11-392]
----------------
G
R
E
S
I
I
A
D
----
F
-------
G
L
W
R
NY
V
A
K
D
L
I
S
DC
S
-
S
----
T
T
Y
V
L
V
T
D
T
N
I
G
S
I
Y
T
P
S
F
E
E
A
F
R
K
R
A
--------
A
E
ITP
S
P
R
L
L
I
Y
N
---------
R
P
--
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
--
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
----
E
F
T
A
L
E
-------
E
----------------
N
-------
A
E
T
I
L
K
A
V
R
R
E
V
T
PGEHRFEGT
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
-----
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
P
-
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
R
I
R
K
L
T
AGKHC
S
V
D
Q
-----------
L
M
F
-----------
N
M
A
L
D
K
K
------------
I
V
L
L
S
A
I
G
T
-
P
Y
E
--
T
R
A
---
S
V
V
A
N
E
D
I
R
V
V
L
A
---
24
PsiBlast_CBE
79.77
38%
-93
- C4 -
3ZOK
11
DHQS_ACTCH
B:
[19-352]
-----------
V
D
L
G
D
R
S
Y
P
I
Y
I
G
SGLL
D
-------
Q
-
P
D
-------
L
L
--
Q
-
R
HVHG
K
R
V
L
V
V
T
N
S
T
V
A
P
I
Y
L
D
K
V
V
G
A
L
T
--
N
ENPN----
V
S
------
V
E
S
V
I
---------
L
P
--
D
G
E
K
Y
K
N
M
D
T
L
M
K
V
F
D
K
A
I
E
--
S
R
--
L
D
R
R
C
T
F
V
A
L
G
G
G
V
I
G
D
M
C
G
Y
A
A
A
S
F
L
R
G
V
N
F
I
Q
I
P
T
T
V
M
A
Q
V
D
S
S
V
G
G
K
T
G
I
N
H
R
L
G
K
N
L
I
G
A
F
Y
Q
P
Q
C
V
L
I
D
T
D
T
L
N
T
L
P
D
R
E
L
A
S
G
L
A
E
V
V
K
Y
G
L
I
R
D
A
N
----
F
F
E
W
Q
E
KNMPALM
A
----------------
R
-------
D
---------------------
P
S
--------
A
L
A
Y
A
I
K
R
S
C
E
N
K
A
E
V
V
S
L
D
E
K
E
S
G
L
R
A
T
L
N
L
G
H
T
F
G
H
A
I
E
T
G
F
G
Y
G
Q
W
L
H
G
E
A
V
A
A
G
M
V
M
A
V
D
M
S
Y
R
L
G
W
I
D
E
S
I
V
N
R
A
H
N
I
L
Q
---
Q
A
K
L
P
T
A
P
P
E
T
-
M
-----------
T
V
E
M
-----------
F
K
S
-----------
V
M
A
V
D
K
K
V
-----
A
D
G
L
L
R
L
I
L
L
K
G
P
L
G
-
N
C
V
--
F
-----
T
G
D
Y
D
R
K
A
L
D
E
T
L
H
A
F
23
PsiBlast_CBE
79.61
38%
-93
- C4 -
3ZOK
10
DHQS_ACTCH
C:
[19-352]
-----------
V
D
L
G
D
R
S
Y
P
I
Y
I
G
SGLL
D
-------
Q
-
P
D
-------
L
L
--
Q
-
R
HVHG
K
R
V
L
V
V
T
N
S
T
V
A
P
I
Y
L
D
K
V
V
G
A
L
T
--
N
ENPN----
V
S
------
V
E
S
V
I
---------
L
P
--
D
G
E
K
Y
K
N
M
D
T
L
M
K
V
F
D
K
A
I
E
--
S
R
--
L
D
R
R
C
T
F
V
A
L
G
G
G
V
I
G
D
M
C
G
Y
A
A
A
S
F
L
R
G
V
N
F
I
Q
I
P
T
T
V
M
A
Q
V
D
S
S
V
G
G
K
T
G
I
N
H
R
L
G
K
N
L
I
G
A
F
Y
Q
P
Q
C
V
L
I
D
T
D
T
L
N
T
L
P
D
R
E
L
A
S
G
L
A
E
V
V
K
Y
G
L
I
R
D
A
N
----
F
F
E
W
Q
E
KNMPALM
A
----------------
R
-------
D
---------------------
P
S
--------
A
L
A
Y
A
I
K
R
S
C
E
N
K
A
E
V
V
S
L
D
E
K
E
S
G
L
R
A
T
L
N
L
G
H
T
F
G
H
A
I
E
T
G
F
G
Y
G
Q
W
L
H
G
E
A
V
A
A
G
M
V
M
A
V
D
M
S
Y
R
L
G
W
I
D
E
S
I
V
N
R
A
H
N
I
L
Q
---
Q
A
K
L
P
T
A
P
P
E
T
-
M
-----------
T
V
E
M
-----------
F
K
S
-----------
V
M
A
V
D
K
K
V
-----
A
D
G
L
L
R
L
I
L
L
K
G
P
L
G
-
N
C
V
--
F
-----
T
G
D
Y
D
R
K
A
L
D
E
T
L
H
A
F
29
PsiBlast_CBE
74.33
38%
-101
- C4 -
1NVE
3
ARO1_EMENI
D:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
EFTA
L
E
E
N
A
E
-------
T
ILKAVRREVTPGEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
GKHCSVDQLMF
N
M
A
L
--------------
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
---
26
PsiBlast_CBE
73.98
38%
-108
- C4 -
1SG6
2
ARO1_EMENI
B:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
R
E
V
T
PGEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
----
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
G
K
H
C
S
V
D
Q
L
M
F
N
M
A
L
-------------
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
---
4
PsiBlast_PDB
73.37
35%
-99
- C4 -
3QBE
3
AROB_MYCTU
A:
[46-344]
--------------------------------------------------------------------
V
A
V
V
H
Q
P
G
L
A
E
T
A
E
--
E
--------
I
R
------
K
R
L
A
G
K
GVD
A
H
R
I
E
I
P
--
D
A
E
A
G
K
D
L
P
V
V
G
F
I
W
E
V
L
G
R
--
I
G
--
I
G
R
K
D
A
L
V
S
L
G
G
G
A
A
T
D
V
A
G
F
A
A
A
T
W
L
R
G
V
S
I
V
H
L
P
T
T
L
L
G
M
V
D
A
A
V
G
G
K
T
G
I
N
T
D
A
G
K
N
L
V
G
A
F
H
Q
P
L
A
V
L
V
D
L
A
T
L
Q
T
L
P
R
D
E
M
I
C
G
M
A
E
V
V
K
A
G
F
I
A
D
P
V
----
I
L
D
L
I
E
-------
A
D
P
Q
A
A
L
----------
D
-------
P
A
--------------------
G
D
--------
V
L
P
E
L
I
R
R
A
I
T
V
K
A
E
V
V
A
A
----
S
E
L
R
E
I
L
N
Y
G
H
T
L
G
H
A
I
E
R
R
E
R
Y
-
R
W
R
H
G
A
A
V
S
V
G
L
V
F
A
A
E
L
A
R
L
A
G
R
L
D
D
A
T
A
Q
R
H
R
T
I
L
S
---
S
L
G
L
-
P
V
S
Y
D
P
-
D
-----------
A
L
P
Q
-----------
L
L
E
-----------
I
M
A
G
D
K
K
T
-----
R
A
G
V
L
R
F
V
V
L
D
G
L
A
K
-
P
G
R
--
M
-----
V
G
P
D
P
G
L
L
V
T
A
Y
A
G
V
C
31
PsiBlast_CBE
72.94
38%
-104
- C4 -
1NVE
2
ARO1_EMENI
B:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
R
E
V
T
P
GEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
G
K
H
C
S
V
D
Q
L
M
F
N
M
A
L
-------------
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
P
--
56
HHSearch
72.82
29%
-106
- C4 -
1XAH
2
AROB_STAAR
A:
[2-349]
--------
K
L
Q
T
T
Y
P
S
N
N
Y
P
I
Y
V
E
----
H
-------
G
A
I
K
Y
I
G
T
Y
--
L
N
--
Q
-
F
----
D
Q
S
F
L
L
I
D
E
Y
V
N
Q
Y
F
A
N
K
F
D
------
N
--------
V
H
--------
K
V
I
---------
I
P
--
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
--
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
-
H
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
----
A
T
Q
D
I
E
-------
Q
----------------
H
-------
F
K
D
R
E
I
L
Q
S
-------------
L
N
--------
G
M
D
K
Y
I
A
K
G
I
E
T
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
Y
Y
H
K
---
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
F
-
D
S
K
H
D
I
S
H
Y
I
Q
Y
L
I
---
Q
L
G
Y
-
P
L
D
-------------------------------------------------------------
G
V
Q
M
V
L
M
R
Q
F
G
D
-
I
V
V
--
Q
------
H
V
D
Q
L
T
L
Q
H
A
C
E
Q
L
K
25
PsiBlast_CBE
72.61
35%
-104
- C4 -
3QBD
1
AROB_MYCTU
B:
[46-344]
--------------------------------------------------------------------
V
A
V
V
H
Q
P
G
L
A
E
T
A
E
--
E
--------
I
R
------
K
R
L
A
G
KGVDAHRIE
I
P
--
D
A
E
A
G
K
D
L
P
V
V
G
F
I
W
E
V
L
G
R
--
I
G
--
I
G
R
K
D
A
L
V
S
L
G
G
G
A
A
T
D
V
A
G
F
A
A
A
T
W
L
R
G
V
S
I
V
H
L
P
T
T
L
L
G
M
V
D
A
A
V
G
G
K
T
G
I
N
T
D
A
G
K
N
L
V
G
A
F
H
Q
P
L
A
V
L
V
D
L
A
T
L
Q
T
L
P
R
D
E
M
I
C
G
M
A
E
V
V
K
A
G
F
I
A
D
P
V
----
I
L
D
L
I
E
-------
A
DPQAAL----------
D
-------
P
A
--------------------
G
D
--------
V
L
P
E
L
I
R
R
A
I
T
V
K
A
E
V
V
A
A
-----
E
L
R
E
I
L
N
Y
G
H
T
L
G
H
A
I
E
R
R
E
R
Y
-
R
W
R
H
G
A
A
V
S
V
G
L
V
F
A
A
E
L
A
R
L
A
G
R
L
D
D
A
T
A
Q
R
H
R
T
I
L
S
---
S
L
G
L
-
P
V
S
Y
D
P
-
D
-----------
A
L
P
Q
-----------
L
L
E
-----------
I
M
A
-------------
V
L
R
F
V
V
L
D
G
L
A
K
-
P
G
R
--
M
-----
V
G
P
D
P
G
L
L
V
T
A
Y
A
G
V
C
53
HHSearch
72.03
28%
-94
- C4 -
2GRU
8
DOIS_BACCI
A:
[2-367]
-------
T
T
K
Q
I
C
F
A
D
R
C
F
N
F
A
F
G
----
E
-------
H
V
L
E
S
V
E
S
Y
--
I
P
R-
D
E
F
----
D
Q
Y
I
M
I
S
D
S
G
V
P
D
S
I
V
H
Y
A
A
E
Y
F
G
K
-
L
--------
A
P
------
V
H
I
L
R
---------
F
Q
--
G
G
E
E
Y
K
T
L
S
T
V
T
N
L
Q
E
R
A
I
A
--
L
G
--
A
N
R
R
T
A
I
V
A
V
G
G
G
L
T
G
N
V
A
G
V
A
A
G
M
M
F
R
G
I
A
L
I
H
V
P
T
T
F
L
A
A
S
D
S
V
L
S
I
K
Q
A
V
N
L
T
S
G
K
N
L
V
G
F
Y
Y
P
P
R
F
V
F
A
D
T
R
I
L
S
E
S
P
P
R
Q
V
K
A
G
M
C
E
L
V
K
N
M
L
I
L
E
N
D
----
N
K
E
F
T
E
-------
D
----------------
D
LNSANV-
Y
S
--------------------
P
K
--------
Q
L
E
T
F
I
N
F
C
I
S
A
K
M
S
V
L
S
E
D
I
Y
E
K
K
K
G
L
I
F
E
Y
G
H
T
I
G
H
A
I
E
L
A
E
Q
G
-
G
I
T
H
G
E
A
I
A
V
G
M
I
Y
A
A
K
I
A
N
R
M
N
L
M
P
E
H
D
V
S
A
H
Y
W
L
L
N
---
K
I
G
A
-
L
Q
D
I
P
L
K
S
-----------
D
P
D
S
-----------
I
F
H
-----------
Y
L
I
H
D
N
K
R
GYIKL
D
E
D
N
L
G
M
I
L
L
S
G
V
G
K
-
P
A
M
--
Y
NQTL
L
T
P
V
R
K
T
L
I
K
E
V
I
R
E
G
L
9
PsiBlast_PDB
71.49
38%
-103
- C4 -
1NVA
3
ARO1_EMENI
A:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
REVTPGEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
----
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
G
K
H
C
S
V
D
Q
L
M
F
N
M
A
L
D
----------
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
---
14
PsiBlast_PDB
71.37
38%
-99
- C4 -
1SG6
2
ARO1_EMENI
A:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
R
E
V
T
PGEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
-----
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
GKHCS
V
D
Q
L
M
F
N
M
A
L
D
K
K
------------
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
---
12
PsiBlast_PDB
71.29
38%
-100
- C4 -
1NVE
3
ARO1_EMENI
A:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
REVTPGEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
---
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
G
K
H
C
S
V
D
Q
L
M
F
N
M
A
---------------
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
P
--
3
PsiBlast_PDB
70.99
35%
-106
- C4 -
3QBD
1
AROB_MYCTU
A:
[46-344]
--------------------------------------------------------------------
V
A
V
V
H
Q
P
G
L
A
E
T
A
E
--
E
--------
I
R
------
K
R
L
A
G
K
GVD
A
H
R
I
E
I
P
--
D
A
E
A
G
K
D
L
P
V
V
G
F
I
W
E
V
L
G
R
--
I
G
--
I
G
R
K
D
A
L
V
S
L
G
G
G
A
A
T
D
V
A
G
F
A
A
A
T
W
L
R
G
V
S
I
V
H
L
P
T
T
L
L
G
M
V
D
A
A
V
G
G
K
T
G
I
N
T
D
A
G
K
N
L
V
G
A
F
H
Q
P
L
A
V
L
V
D
L
A
T
L
Q
T
L
P
R
D
E
M
I
C
G
M
A
E
V
V
K
A
G
F
I
A
D
P
V
----
I
L
D
L
I
E
-------
A
D
P
Q
A
A
L
----------
D
-------
P
A
--------------------
G
D
--------
V
L
P
E
L
I
R
R
A
I
T
V
K
A
E
V
V
A
A
-----
E
L
R
E
I
L
N
Y
G
H
T
L
G
H
A
I
E
R
R
E
R
Y
-
R
W
R
H
G
A
A
V
S
V
G
L
V
F
A
A
E
L
A
R
L
A
G
R
L
D
D
A
T
A
Q
R
H
R
T
I
L
S
---
S
L
G
L
-
P
V
S
Y
D
P
-
D
-----------
A
L
P
Q
-----------
L
L
E
-----------
I
M
A
G
------------
V
L
R
F
V
V
L
D
G
L
A
K
-
P
G
R
--
M
-----
V
G
P
D
P
G
L
L
V
T
A
Y
A
G
V
C
38
PsiBlast_CBE
70.52
38%
-90
- C4 -
1DQS
5
ARO1_EMENI
B:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
R------------------
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
G
K
H
C
S
V
D
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
P
--
37
PsiBlast_CBE
70.01
38%
-90
- C4 -
1NR5
4
ARO1_EMENI
B:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
R
E
V
T
P
GEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
GKHCS
V
D
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
P
--
6
PsiBlast_PDB
69.71
38%
-90
- C4 -
1NR5
4
ARO1_EMENI
A:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
R
E
V
T
PGEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
G
K
H
C
S
V
D
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
---
32
PsiBlast_CBE
69.61
38%
-88
- C4 -
1NVD
3
ARO1_EMENI
B:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
RRF--------
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
G
K
H
C
S
V
D
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
P
--
11
PsiBlast_PDB
69.54
38%
-89
- C4 -
1NVD
4
ARO1_EMENI
A:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
REVRF-----
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
G
K
H
C
S
V
D
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
P
--
7
PsiBlast_PDB
69.39
38%
-106
- C4 -
1NRX
4
ARO1_EMENI
A:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
REVTPGHRF-
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
---
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
G
K
H
C
S
V
D
Q
L
M
F
N
M
A
L
D
----------
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
---
34
PsiBlast_CBE
68.87
38%
-99
- C4 -
1NVA
3
ARO1_EMENI
B:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
R
E
V
T
P
GEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
---
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
G
K
H
C
S
V
D
Q
L
M
F
N
M
A
L
D
K
--------
G
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
---
5
PsiBlast_PDB
68.70
38%
-88
- C4 -
1DQS
5
ARO1_EMENI
A:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
RRF-------
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
GKHCS
V
D
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
----
13
PsiBlast_PDB
68.42
38%
-85
- C4 -
1NVF
5
ARO1_EMENI
A:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
REVTPGEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
G
K
H
C
S
V
D
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
----
28
PsiBlast_CBE
68.16
38%
-87
- C4 -
1NVF
4
ARO1_EMENI
B:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
EFTA
L
E
E
N
A
E
-------
T
ILKAVRREVTPGEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
GKHCSVDQLMF
N
M
A
L
D
K
K
N
-----
D
G
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
----
42
PsiBlast_CBE
67.73
33%
-94
- C4 -
1XAH
2
AROB_STAAR
B:
[59-348]
-----------------------------------------------------------------------------------------------------
V
H
K
V
I
---------
I
P
--
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
--
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
H
-
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
----
A
T
Q
D
I
E
------------------------
Q
-------
H
F
--------------------
K
D
REILQSLN
G
M
D
K
Y
I
A
K
G
I
E
T
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
---
Y
Y
H
K
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
F
D
S
K
H
D
I
S
H
Y
I
Q
Y
L
I
Q
LGY
P
L
D
------------------------
T
-----------
L
Y
Q
-----------
Y
M
L
-------------
G
V
Q
M
V
L
M
R
Q
F
G
D
-
I
-
V
--
V
-----
Q
H
V
D
Q
L
T
L
Q
H
A
C
E
Q
L
K
10
PsiBlast_PDB
66.88
38%
-83
- C4 -
1NVB
5
ARO1_EMENI
A:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
REVTPGEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
G
K
H
C
S
V
D
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
---
36
PsiBlast_CBE
66.60
38%
-103
- C4 -
1NRX
6
ARO1_EMENI
B:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
-------
T
I
L
K
A
V
R
R
E
V
T
PGEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
---
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
G
K
H
C
S
V
D
Q
L
M
F
N
M
A
L
D
----------
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R
-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
P
--
33
PsiBlast_CBE
66.50
38%
-84
- C4 -
1NVB
2
ARO1_EMENI
B:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
EFTA
L
E
E
N
A
E
-------
T
ILKAVRREVTPGEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
GKHCSVDQLMF
N
M
A
L
D
K
K
N
-----
D
G
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
A
P
--
27
PsiBlast_CBE
65.74
38%
-85
- C4 -
1NVF
4
ARO1_EMENI
C:
[104-391]
--------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
EFTA
L
E
E
N
A
E
-------
T
ILKAVRREVTPGEHRF
E
-------
G
T
--------------------
E
E
--------
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
G
I
L
K
G
V
A
V
S
R
I
V
K
C
L
A
---
A
Y
G
L
-
P
T
S
L
K
D
-
A
-----------
R
I
R
K
-----------
L
T
A
GKHCSVDQLMF
N
M
A
L
D
K
K
N
-----
D
G
P
K
K
K
I
V
L
L
S
A
I
G
T
P
Y
E
T
R-
A
-----
S
V
V
A
N
E
D
I
R
V
V
L
----
16
PsiBlast_PDB
65.60
33%
-90
- C4 -
1XAH
2
AROB_STAAR
A:
[59-348]
-----------------------------------------------------------------------------------------------------
V
H
K
V
I
---------
I
P
--
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
--
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
H
-
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
----
A
T
Q
D
I
E
------------------------
Q
-------
H
F
--------------------
K
D
R
E
I
L
Q
S
LN
G
M
D
K
Y
I
A
K
G
I
E
T
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
---
Y
Y
H
K
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
F
D
S
K
H
D
I
S
H
Y
I
Q
Y
L
I
Q
L
GY
P
L
D
------------------------------------------------------------------
G
V
Q
M
V
L
M
R
Q
F
G
D
-
I
-
V
--
V
-----
Q
H
V
D
Q
L
T
L
Q
H
A
C
E
Q
L
K
15
PsiBlast_PDB
64.41
33%
-83
- C4 -
1XAG
5
AROB_STAAR
A:
[59-348]
-----------------------------------------------------------------------------------------------------
V
H
K
V
I
---------
I
P
--
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
--
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
H
-
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
----
A
T
Q
D
I
E
------------------------
Q
-------
H
F
--------------------
K
D
R
E
I
L
Q
S
LN
G
M
D
K
Y
I
A
K
G
I
E
T
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
---
Y
Y
H
K
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
F
D
S
K
H
D
I
S
H
Y
I
Q
Y
L
I
Q
L
GY
P
L
D
M
-
I
T
D
----
L
-----------
D
F
E
T
-----------
L
Y
Q
-----------
Y
M
L
S
D
K
K
N
-----
D
K
Q
G
V
Q
M
V
L
M
R
Q
F
G
D
-
I
-
V
--
V
-----
Q
H
V
D
Q
L
T
L
Q
H
A
C
E
Q
L
K
41
PsiBlast_CBE
63.56
33%
-80
- C4 -
1XAI
3
AROB_STAAR
B:
[59-348]
-----------------------------------------------------------------------------------------------------
V
H
K
V
I
---------
I
P
--
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
--
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
H
-
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
----
A
T
Q
D
I
E
------------------------
Q
-------
H
F
--------------------
K
D
REILQSLN
G
M
D
K
Y
I
A
K
G
I
E
T
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
---
Y
Y
H
K
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
F
D
S
K
H
D
I
S
H
Y
I
Q
Y
L
I
Q
LGY
P
L
D
M
-
I
T
D
----
L
-----------
D
F
E
T
-----------
L
Y
Q
-----------
Y
M
L
S
D
K
K
N
-----
D
K
Q
G
V
Q
M
V
L
M
R
Q
F
G
D
-
I
-
V
--
V
-----
Q
H
V
D
Q
L
T
L
Q
H
A
C
E
Q
L
K
17
PsiBlast_PDB
62.89
33%
-78
- C4 -
1XAI
3
AROB_STAAR
A:
[59-348]
-----------------------------------------------------------------------------------------------------
V
H
K
V
I
---------
I
P
--
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
--
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
H
-
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
----
A
T
Q
D
I
E
------------------------
Q
-------
H
F
--------------------
K
D
R
E
I
L
Q
S
LN
G
M
D
K
Y
I
A
K
G
I
E
T
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
---
Y
Y
H
K
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
F
D
S
K
H
D
I
S
H
Y
I
Q
Y
L
I
Q
L
GY
P
L
D
M
-
I
T
D
----
L
-----------
D
F
E
T
-----------
L
Y
Q
-----------
Y
M
L
S
D
K
K
N
-----
D
K
Q
G
V
Q
M
V
L
M
R
Q
F
G
D
-
I
-
V
--
V
-----
Q
H
V
D
Q
L
T
L
Q
H
A
C
E
Q
L
K
18
PsiBlast_PDB
61.74
33%
-80
- C4 -
1XAJ
4
AROB_STAAR
A:
[59-348]
-----------------------------------------------------------------------------------------------------
V
H
K
V
I
---------
I
P
--
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
--
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
H
-
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
----
A
T
Q
D
I
E
------------------------
Q
-------
H
F
--------------------
K
D
R
E
I
L
Q
S
LN
G
M
D
K
Y
I
A
K
G
I
E
T
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
---
Y
Y
H
K
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
F
D
S
K
H
D
I
S
H
Y
I
Q
Y
L
I
Q
L
GY
P
L
D
M
-------------------------------------------------
Y
M
L
S
D
K
K
N
-----
D
K
Q
G
V
Q
M
V
L
M
R
Q
F
G
D
-
I
-
V
--
V
-----
Q
H
V
D
Q
L
T
L
Q
H
A
C
E
Q
L
K
19
PsiBlast_PDB
61.06
33%
-83
- C4 -
1XAL
4
AROB_STAAR
A:
[59-348]
-----------------------------------------------------------------------------------------------------
V
H
K
V
I
---------
I
P
--
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
--
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
H
-
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
----
A
T
Q
D
I
E
------------------------
Q
-------
H
F
--------------------
K
D
R
E
I
L
Q
S
LN
G
M
D
K
Y
I
A
K
G
I
E
T
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
---
Y
Y
H
K
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
F
D
S
K
H
D
I
S
H
Y
I
Q
Y
L
I
Q
L
GY
P
L
D
M
--------------------------------------------------
M
L
S
D
K
K
N
-----
D
K
Q
G
V
Q
M
V
L
M
R
Q
F
G
D
-
I
-
V
--
V
-----
Q
H
V
D
Q
L
T
L
Q
H
A
C
E
Q
L
K
39
PsiBlast_CBE
60.31
33%
-83
- C4 -
1XAL
4
AROB_STAAR
B:
[59-348]
-----------------------------------------------------------------------------------------------------
V
H
K
V
I
---------
I
P
--
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
--
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
H
-
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
----
A
T
Q
D
I
E
------------------------
Q
-------
H
F
--------------------
K
D
REILQSLN
G
M
D
K
Y
I
A
K
G
I
E
T
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
---
Y
Y
H
K
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
F
D
S
K
H
D
I
S
H
Y
I
Q
Y
L
I
Q
LGY
P
L
D
M
--------------------------------------------------
M
L
S
D
K
K
N
-----
D
K
Q
G
V
Q
M
V
L
M
R
Q
F
G
D
-
I
-
V
--
V
-----
Q
H
V
D
Q
L
T
L
Q
H
A
C
E
Q
L
K
40
PsiBlast_CBE
59.49
33%
-78
- C4 -
1XAJ
4
AROB_STAAR
B:
[59-348]
-----------------------------------------------------------------------------------------------------
V
H
K
V
I
---------
I
P
--
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
--
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
H
-
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
----
A
T
Q
D
I
E
------------------------
Q
-------
H
F
--------------------
K
D
REILQSLN
G
M
D
K
Y
I
A
K
G
I
E
T
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
---
Y
Y
H
K
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
F
D
S
K
H
D
I
S
H
Y
I
Q
Y
L
I
Q
LGY
P
L
D
M
-------------------------------------------------
Y
M
L
S
D
K
K
N
-----
D
K
Q
G
V
Q
M
V
L
M
R
Q
F
G
D
-
I
-
V
--
V
-----
Q
H
V
D
Q
L
T
L
Q
H
A
C
E
Q
L
K