@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0286: (2015-12-14 )
MILEVKDLKTYFFTDKGVNKAVDGVSFGLKKSQTLCIVGESGSGKSITSLSILGLIEKPGKIVGGSIQFLGQDLLQLKEKQMQKEIRGKKIGMIFQEPMTSLNPSYTVGFQINEVLKIHHPSLNKKERLERVVYELERVGIPHAGDKYHEYPFNLSGGQRQRVMIAMAMVCEPEILIADEPTTALDVTIQAQILELMKELQQKKGTSILFITHDLGVVAQIADEVVVMYKGHVVEQASAKELFADPRHPYTKALLNAIPKPGKEYRKKRLETVDENVDYLSFQKELR
Atome Classification :
(33 SA)
.........10........20........30........40........50......--.--.60........70........80-------.........90........100.......110...-....120.......130....-...140........150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260......---------------.270.......280.....---------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
I
L
E
V
K
D
L
K
T
Y
F
FTDKGV
N
K
A
V
D
G
V
SFGLKKS
Q
T
L
C
I
V
GESGSG
K
S
I
T
S
L
S
I
L
G
LIE--K--PGKIVG
G
S
I
Q
F
L
G
Q
D
L
L
Q
L
K
E
K
--------
Q
M
Q
K
E
IRGKK
I
G
M
I
FQEP
M
T
SLNP
S
Y
T
V
G
F
Q
I
N
E
V
-
L
K
IHHPSL
N
K
K
E
R
L
E
R
V
V
Y
E
L
-
E
R
VGI-PHAGDKYHEYPFNLSGGQ
R
Q
R
V
M
I
A
M
A
MVCEP
E
I
L
I
ADEPT
T
A
L
D
V
T
I
Q
A
Q
I
L
E
L
M
K
E
L
Q
QKKG
T
S
I
L
F
I
TH
D
L
G
V
V
A
Q
I
A
D
E
V
V
V
M
YKG
H
V
VEQA
S
A
K
E
LFADPRH
P
Y
T
K
A
L
L
NAIPKP
G
K
E
Y
R
K
K
---------------
R
L
E
T
V
DENV
D
Y
L
S
F
Q
K
ELR---------------------------------------------------
108
Fugue
92.16
34%
-104
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
-
T
L
I
R
C
V
N
L
L
E
--
R
--
P
T
E
---
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
--------
E
L
T
K
A
R
R
Q
--
I
G
M
I
F
Q
H
F
--
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
-
L
E
L
D
N
T
P
--
K
D
E
V
K
R
R
V
T
E
L
L
-
S
L
V
G
L
-
G
---
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
ERLQAEPFTDCVPML
R
L
E
F
T
G
Q
S
V
D
A
P
L
L
S
E
T
A
R
RFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV
1
PsiBlast_PDB
84.76
38%
-114
- C1 -
4FWI
3
?
B:
[3-258]
I
I
I
R
V
E
D
L
R
A
V
Y
L
V
R
E
G
T
I
K
A
A
D
G
I
S
L
D
I
L
E
N
S
V
T
A
I
V
G
E
S
A
S
G
K
S
T
I
I
E
A
M
T
K
T
L
P
--
P
--
N
G
R
I
L
S
G
R
V
L
Y
K
G
K
D
L
L
T
M
R
E
E
--------
E
L
R
K
-
I
R
W
K
E
I
A
L
V
P
Q
A
A
Q
Q
S
L
N
P
T
M
K
V
I
E
H
F
K
D
T
-
V
E
A
H
G
V
R
W
S
H
S
E
L
I
E
K
A
S
E
K
L
-
R
M
V
R
L
N
P
E
A
--
V
L
N
S
Y
P
L
Q
L
S
G
G
M
K
Q
R
V
L
I
A
L
A
L
L
L
D
P
V
V
L
I
L
D
E
P
T
S
A
L
D
V
L
T
Q
A
H
I
I
Q
L
L
K
E
L
K
K
M
L
K
I
T
L
I
F
V
T
H
D
I
A
V
A
A
E
L
A
D
K
V
A
V
I
Y
G
G
N
L
V
E
Y
N
S
T
F
Q
I
F
K
N
P
L
H
P
Y
T
R
G
L
I
N
S
I
M
P
I
P
G
D
P
P
S
L
---------------
L
N
P
P
S
G
C
R
F
H
P
R
C
E
Y
A
M
E
I
---------------------------------------------------
4
PsiBlast_PDB
82.79
34%
-102
- C1 -
3TUZ
1
METN_ECOLI
C:
[24-266]
-
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
-
T
L
I
R
C
V
N
L
L
E
--
R
--
P
T
E
---
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
--------
E
L
T
K
A
R
R
--
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
---
N
V
A
-
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
-
S
L
V
G
L
----
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
---------------
E
R
L
Q
A
E
P
F
T
D
C
V
P
M
L
R
L
E
F
---------------------------------------------------
24
PsiBlast_CBE
80.57
34%
-105
- C1 -
3TUI
1
METN_ECOLI
H:
[24-266]
-
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
-
T
L
I
R
C
V
N
L
L
E
--
R
--
P
T
E
---
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
--------
E
L
T
K
A
R
R
--
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
---
N
V
A
-
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
-
S
L
V
G
L
----
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
---------------
E
R
L
Q
A
E
P
F
T
D
C
V
P
M
L
R
L
E
F
---------------------------------------------------
23
PsiBlast_CBE
79.86
34%
-99
- C1 -
3TUZ
1
METN_ECOLI
D:
[24-266]
-
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
-
T
L
I
R
C
V
N
L
L
E
--
R
--
P
T
E
---
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
--------
E
L
T
K
A
R
R
--
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
---
N
V
A
-
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
-
S
L
V
G
L
----
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
---------------
E
R
L
Q
A
E
P
F
T
D
C
V
P
M
L
R
L
E
F
---------------------------------------------------
3
PsiBlast_PDB
79.75
34%
-99
- C1 -
3TUI
1
METN_ECOLI
C:
[24-266]
-
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
-
T
L
I
R
C
V
N
L
L
E
--
R
--
P
T
E
---
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
--------
E
L
T
K
A
R
R
--
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
---
N
V
A
-
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
-
S
L
V
G
L
----
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
---------------
E
R
L
Q
A
E
P
F
T
D
C
V
P
M
L
R
L
E
F
---------------------------------------------------
21
PsiBlast_CBE
79.54
34%
-107
- C1 -
3TUZ
1
METN_ECOLI
H:
[24-266]
-
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
-
T
L
I
R
C
V
N
L
L
E
--
R
--
P
T
E
---
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
--------
E
L
T
K
A
R
R
--
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
---
N
V
A
-
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
-
S
L
V
G
L
----
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
---------------
E
R
L
Q
A
E
P
F
T
D
C
V
P
M
L
R
L
E
F
---------------------------------------------------
22
PsiBlast_CBE
79.34
34%
-98
- C1 -
3TUZ
1
METN_ECOLI
G:
[24-266]
-
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
-
T
L
I
R
C
V
N
L
L
E
--
R
--
P
T
E
---
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
--------
E
L
T
K
A
R
R
--
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
---
N
V
A
-
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
-
S
L
V
G
L
----
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
---------------
E
R
L
Q
A
E
P
F
T
D
C
V
P
M
L
R
L
E
F
---------------------------------------------------
7
PsiBlast_PDB
78.68
33%
-95
- C1 -
4U02
1
?
A:
[4-241]
-
I
I
R
I
R
N
L
H
K
W
F
----
G
P
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
-
T
L
I
R
T
I
N
R
L
E
DF
Q
--
E
G
E
V
V
--------
V
D
G
L
S
V
K
D
D
--------
R
A
L
R
E
I
R
-
R
E
V
G
M
V
F
Q
Q
--
F
N
L
F
P
H
M
T
V
--
L
E
N
V
T
-
L
A
P
M
R
V
R
R
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
-
L
---
D
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
-
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
R
V
L
H
---------------------------------------------------------------------------------------------
105
HHSearch
78.13
31%
-101
- C1 -
1B0U
4
HISP_SALTY
A:
[6-253]
-
K
L
H
V
I
D
L
H
K
R
Y
G
G
----
H
E
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
--
P
------
S
E
G
A
I
I
V
N
G
Q
N
I
N
L
V
R
D
K
DGQLKVAD
K
N
Q
L
R
L
L
R
T
R
L
T
M
V
F
Q
H
F
N
L
--
W
S
H
M
T
V
L
E
N
V
M
E
A
-
P
I
Q
V
L
-
G
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
-
A
K
V
G
I
-
D
E
R
A
--
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
E
-
E
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
Q
S
P
R
L
Q
Q
F
L
K
G
S
L
K
K
L
E
H
-----------------------------------------------------------------------------------------
25
PsiBlast_CBE
77.62
34%
-100
- C1 -
3TUI
1
METN_ECOLI
G:
[24-266]
-
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
-
T
L
I
R
C
V
N
L
L
E
--
R
--
P
T
E
---
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
--------
E
L
T
K
A
R
R
--
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
---
N
V
A
-
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
-
S
L
V
G
L
----
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
---------------
E
R
L
Q
A
E
P
F
T
D
C
V
P
M
L
R
L
E
F
---------------------------------------------------
87
HHSearch
77.55
36%
-101
- C1 -
3TUI
1
METN_ECOLI
C:
[23-258]
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
--
P
------
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
--------
E
L
T
K
--
A
R
R
Q
I
G
M
I
F
Q
H
F
N
--
L
L
S
S
R
T
V
F
G
N
V
A
L
P
-
L
E
L
D
N
T
--
P
K
D
E
V
K
R
R
V
T
E
L
L
-
S
L
V
G
L
-
G
D
---
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
---------------
E
R
L
Q
A
E
P
F
T
D
C
V
P
M
L
R
L
E
F
---------------------------------------------------
10
PsiBlast_PDB
76.51
33%
-104
- C1 -
2OUK
1
?
A:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
-
T
F
L
R
C
L
N
L
L
E
--
D
F
D
E
G
E
I
I
I
D
G
I
N
------
L
K
A
K
D
T
--------
N
L
N
K
-
V
R
-
E
E
V
G
M
V
F
Q
R
--
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
--
A
K
A
M
E
L
L
-
D
K
V
G
L
-
K
---
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
6
PsiBlast_PDB
76.42
33%
-95
- C1 -
4U00
3
?
A:
[4-241]
-
I
I
R
I
R
N
L
H
K
W
F
----
G
P
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
-
T
L
I
R
T
I
N
R
L
E
DF
Q
--
E
G
E
V
V
--------
V
D
G
L
S
V
K
D
D
--------
R
A
L
R
E
I
R
-
R
E
V
G
M
V
F
Q
Q
--
F
N
L
F
P
H
M
T
V
--
L
E
N
V
T
-
L
A
P
M
R
V
R
R
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
-
L
---
D
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
-
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
R
V
L
H
---------------------------------------------------------------------------------------------
20
PsiBlast_PDB
76.32
32%
-90
- C1 -
2YYZ
3
?
A:
[4-238]
--
I
R
V
V
N
L
K
K
Y
F
----
G
K
V
K
A
V
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
-
I
Y
--
K
--
P
---
T
S
G
E
I
Y
F
--
D
D
V
L
V
N
D
I
P
--------
P
K
Y
R
E
V
-----
G
M
V
F
Q
N
--
Y
A
L
Y
P
H
M
T
V
-
F
E
-
N
I
A
-
F
P
L
R
A
R
R
I
S
K
D
E
V
E
K
R
V
V
E
I
A
-
R
K
L
L
I
-
D
N
L
L
D
R
K
---
P
T
Q
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
Q
Q
E
L
G
I
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
N
Q
G
K
L
V
Q
Y
G
T
P
D
E
V
Y
D
S
P
K
N
M
F
V
A
S
F
I
G
N
P
P
T
N
F
L
R
D
F
S
V
---------------
S
V
E
N
K
Q
T
I
L
K
R
D
D
V
I
I
K
L
P
---------------------------------------------------
27
PsiBlast_CBE
76.19
33%
-97
- C1 -
4U02
1
?
D:
[4-241]
-
I
I
R
I
R
N
L
H
K
W
F
----
G
P
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
-
T
L
I
R
T
I
N
R
L
E
DF
Q
--
E
G
E
V
V
--------
V
D
G
L
S
V
K
D
D
--------
R
A
L
R
E
I
R
-
R
E
V
G
M
V
F
Q
Q
--
F
N
L
F
P
H
M
T
V
--
L
E
N
V
T
-
L
A
P
M
R
V
R
R
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
-
L
---
D
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
-
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
R
V
L
H
---------------------------------------------------------------------------------------------
26
PsiBlast_CBE
76.11
34%
-95
- C1 -
3TUI
1
METN_ECOLI
D:
[24-266]
-
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
-
T
L
I
R
C
V
N
L
L
E
--
R
--
P
T
E
---
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
--------
E
L
T
K
A
R
R
--
Q
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
---
N
V
A
-
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
-
S
L
V
G
L
----
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
---------------
E
R
L
Q
A
E
P
F
T
D
C
V
P
M
L
R
L
E
F
---------------------------------------------------
28
PsiBlast_CBE
75.81
33%
-100
- C1 -
4U02
1
?
C:
[4-241]
-
I
I
R
I
R
N
L
H
K
W
F
----
G
P
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
-
T
L
I
R
T
I
N
R
L
E
DF
Q
--
E
G
E
V
V
--------
V
D
G
L
S
V
K
D
D
--------
R
A
L
R
E
I
R
-
R
E
V
G
M
V
F
Q
Q
--
F
N
L
F
P
H
M
T
V
--
L
E
N
V
T
-
L
A
P
M
R
V
R
R
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
-
L
---
D
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
-
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
E
R
T
R
S
F
L
Q
R
V
L
H
---------------------------------------------------------------------------------------------
35
PsiBlast_CBE
75.08
33%
-101
- C1 -
2OLK
1
?
D:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
-
T
F
L
R
C
L
N
L
L
E
--
D
FD
E
G
E
I
I
I
D
G
I
N
------
L
K
A
K
D
T
--------
N
L
N
K
-
V
R
-
E
E
V
G
M
V
F
Q
R
--
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
--
A
K
A
M
E
L
L
-
D
K
V
G
L
-
K
---
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
30
PsiBlast_CBE
75.03
33%
-106
- C1 -
3C4J
4
?
B:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
-
T
F
L
R
C
L
N
L
L
E
--
D
FD
E
G
E
I
I
I
D
G
I
N
------
L
K
A
K
D
T
--------
N
L
N
K
-
V
R
-
E
E
V
G
M
V
F
Q
R
--
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
--
A
K
A
M
E
L
L
-
D
K
V
G
L
-
K
---
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
37
PsiBlast_CBE
74.66
33%
-100
- C1 -
2OLK
2
?
B:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
-
T
F
L
R
C
L
N
L
L
E
--
D
FD
E
G
E
I
I
I
D
G
I
N
------
L
K
A
K
D
T
--------
N
L
N
K
-
V
R
-
E
E
V
G
M
V
F
Q
R
--
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
--
A
K
A
M
E
L
L
-
D
K
V
G
L
-
K
---
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
11
PsiBlast_PDB
74.28
33%
-97
- C1 -
2Q0H
4
?
A:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
-
T
F
L
R
C
L
N
L
L
E
--
D
F
D
E
G
E
I
I
I
D
G
I
N
------
L
K
A
K
D
T
--------
N
L
N
K
-
V
R
-
E
E
V
G
M
V
F
Q
R
--
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
--
A
K
A
M
E
L
L
-
D
K
V
G
L
-
K
---
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
13
PsiBlast_PDB
73.73
33%
-94
- C1 -
3C41
3
?
J:
[3-241]
-
M
I
D
V
H
Q
L
K
K
S
F
----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
-
T
F
L
R
C
L
N
L
L
E
--
D
FD
E
G
E
I
I
I
D
G
I
N
------
L
K
A
K
D
T
--------
N
L
N
K
-
V
R
-
E
E
V
G
M
V
F
Q
R
--
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
--
A
K
A
M
E
L
L
-
D
K
V
G
L
-
K
---
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
39
PsiBlast_CBE
73.62
33%
-100
- C1 -
3C41
3
?
K:
[3-241]
-
M
I
D
V
H
Q
L
K
K
S
F
----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
-
T
F
L
R
C
L
N
L
L
E
--
D
FD
E
G
E
I
I
I
D
G
I
N
------
L
K
A
K
D
T
--------
N
L
N
K
-
V
R
-
E
E
V
G
M
V
F
Q
R
--
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
--
A
K
A
M
E
L
L
-
D
K
V
G
L
-
K
---
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
36
PsiBlast_CBE
73.43
33%
-100
- C1 -
2OLK
1
?
C:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
-
T
F
L
R
C
L
N
L
L
E
--
D
FD
E
G
E
I
I
I
D
G
I
N
------
L
K
A
K
D
T
--------
N
L
N
K
-
V
R
-
E
E
V
G
M
V
F
Q
R
--
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
--
A
K
A
M
E
L
L
-
D
K
V
G
L
-
K
---
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
41
PsiBlast_CBE
73.26
32%
-97
- C1 -
4YMU
2
?
A:
[8-239]
------------
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
-
T
L
L
R
C
I
N
L
L
E
--
E
--
P
T
K
---
G
E
V
-
F
I
--
D
G
V
K
I
N
N
G
--------
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
--
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
-
A
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
-
A
K
V
G
L
-
L
---
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
12
PsiBlast_PDB
72.83
33%
-97
- C1 -
3C4J
3
?
A:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
-
T
F
L
R
C
L
N
L
L
E
--
D
FD
E
G
E
I
I
I
D
G
I
N
------
L
K
A
K
D
T
--------
N
L
N
K
-
V
R
-
E
E
V
G
M
V
F
Q
R
--
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
--
A
K
A
M
E
L
L
-
D
K
V
G
L
-
K
---
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
9
PsiBlast_PDB
72.63
33%
-101
- C1 -
2OLK
1
?
A:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
-
T
F
L
R
C
L
N
L
L
E
--
D
FD
E
G
E
I
I
I
D
G
I
N
------
L
K
A
K
D
T
--------
N
L
N
K
-
V
R
-
E
E
V
G
M
V
F
Q
R
--
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
--
A
K
A
M
E
L
L
-
D
K
V
G
L
-
K
---
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
17
PsiBlast_PDB
71.51
32%
-99
- C1 -
4YMV
1
?
J:
[8-239]
------------
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
-
T
L
L
R
C
I
N
L
L
E
--
E
--
P
T
K
---
G
E
V
-
F
I
--
D
G
V
K
I
N
N
G
--------
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
--
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
-
A
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
-
A
K
V
G
L
-
L
---
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
31
PsiBlast_CBE
71.39
33%
-98
- C1 -
2Q0H
4
?
B:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
-
T
F
L
R
C
L
N
L
L
E
--
D
F
D
E
G
E
I
I
I
D
G
I
N
------
L
K
A
K
D
T
--------
N
L
N
K
-
V
R
-
E
E
V
G
M
V
F
Q
R
--
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
--
A
K
A
M
E
L
L
-
D
K
V
G
L
-
K
---
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
40
PsiBlast_CBE
70.41
32%
-96
- C1 -
4YMV
1
?
A:
[8-239]
------------
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
-
T
L
L
R
C
I
N
L
L
E
--
E
--
P
T
K
---
G
E
V
-
F
I
--
D
G
V
K
I
N
N
G
--------
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
--
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
-
A
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
-
A
K
V
G
L
-
L
---
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
16
PsiBlast_PDB
70.10
32%
-96
- C1 -
4YMU
2
?
J:
[8-239]
------------
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
-
T
L
L
R
C
I
N
L
L
E
--
E
--
P
T
K
---
G
E
V
-
F
I
--
D
G
V
K
I
N
N
G
--------
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
--
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
-
A
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
-
A
K
V
G
L
-
L
---
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
38
PsiBlast_CBE
69.36
33%
-97
- C1 -
2OLJ
3
?
B:
[24-262]
-
M
I
D
V
H
Q
L
K
K
S
F
----
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
-
T
F
L
R
C
L
N
L
L
E
--
D
FD
E
G
E
I
I
I
D
G
I
N
------
L
K
A
K
D
T
--------
N
L
N
K
-
V
R
-
E
E
V
G
M
V
F
Q
R
--
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
--
A
K
A
M
E
L
L
-
D
K
V
G
L
-
K
---
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------