@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0395: (2015-12-15 )
MAIFGELGSLGHLFKKTQELEILHGYLQDVMQKGSEANQRVLNLAINTEFQVPLEHGIFSIEQSYCLEHAKEGEKGFFESHRQYVDFQLIIKGVEGAKVADINRAVIKTPYDEKRDLIVYEPVSEASFLHLDAGMLAIFLENDAHALRFYGESFEKYREEPIFKAVVKMPKGLIKLKL
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------.......--..10........20--........30........40........50........60..-......70----........80........90--......------...100-.......-.110.......120.......130.......140.......150.........160.......170......-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------M
A
I
F
G
E
L
--
G
S
L
G
H
L
F
K
K
T
Q
E
L
E
--
I
L
H
G
Y
L
Q
D
V
M
QKGSEAN
Q
R
V
L
N
L
A
IN
T
E
F
Q
V
P
L
E
HG
I
F
S
I
E
Q
-
S
Y
C
L
E
H
A
K----EG
E
K
G
F
F
E
S
H
R
Q
Y
V
D
F
Q
L
I
---
I
KGVEG------
A
K
V
A-D-IN
R
A
VIK-TPYDEKR
D
L
I
V
YEPVSE
A
S
F
L
H
LDA
G
M
L
A
I
F
LEND
A
H
A
L
R
F
Y
--
G
E
S
F
E
K
Y
R
EE
P
I
F
K
A
V
V
KMPKG
L
I
K
LKL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
98.93
88%
-105
- C6 -
4TSD
2
?
B:
[2-178]
-------------------------------------------------------------------------------------------------------------------------------
A
I
F
G
E
L
--
S
S
L
G
H
L
F
K
K
T
Q
E
L
E
--
I
L
H
E
Y
L
K
E
V
M
Q
K
G
S
K
A
N
Q
R
V
L
N
L
A
T
N
T
E
F
Q
V
P
L
G
H
G
I
F
S
I
E
Q
-
S
Y
C
L
E
H
A
K
----
E
S
E
K
G
F
F
E
S
H
K
K
Y
V
D
F
Q
L
I
---
V
K
G
V
E
G
------
A
K
A
V
-
G
-
I
N
Q
A
V
I
K
-
N
P
Y
D
E
K
R
D
L
I
V
Y
E
P
V
S
E
A
S
F
L
R
L
H
A
G
M
L
A
I
F
F
E
N
D
A
H
A
L
R
F
Y
--
G
E
S
F
E
K
Y
R
E
E
P
I
F
K
A
V
V
K
A
P
K
G
L
I
K
L
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
98.79
88%
-106
- C6 -
4TSD
2
?
A:
[2-180]
-------------------------------------------------------------------------------------------------------------------------------
A
I
F
G
E
L
--
S
S
L
G
H
L
F
K
K
T
Q
E
L
E
--
I
L
H
E
Y
L
K
E
V
M
Q
K
G
S
K
A
N
Q
R
V
L
N
L
A
T
N
T
E
F
Q
V
P
L
G
H
G
I
F
S
I
E
Q
-
S
Y
C
L
E
H
A
K
----
E
S
E
K
G
F
F
E
S
H
K
K
Y
V
D
F
Q
L
I
---
V
K
G
V
E
G
------
A
K
A
V
-
G
-
I
N
Q
A
V
I
K
-
N
P
Y
D
E
K
R
D
L
I
V
Y
E
P
V
S
E
A
S
F
L
R
L
H
A
G
M
L
A
I
F
F
E
N
D
A
H
A
L
R
F
Y
--
G
E
S
F
E
K
Y
R
E
E
P
I
F
K
A
V
V
K
A
P
K
G
L
I
K
L
K
L
AA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_CBE
98.24
88%
-106
- C6 -
4TSD
2
?
A:
[2-178]
-------------------------------------------------------------------------------------------------------------------------------
A
I
F
G
E
L
--
S
S
L
G
H
L
F
K
K
T
Q
E
L
E
--
I
L
H
E
Y
L
K
E
V
M
Q
K
G
S
K
A
N
Q
R
V
L
N
L
A
T
N
T
E
F
Q
V
P
L
G
H
G
I
F
S
I
E
Q
-
S
Y
C
L
E
H
A
K
----
E
S
E
K
G
F
F
E
S
H
K
K
Y
V
D
F
Q
L
I
---
V
K
G
V
E
G
------
A
K
A
V
-
G
-
I
N
Q
A
V
I
K
-
N
P
Y
D
E
K
R
D
L
I
V
Y
E
P
V
S
E
A
S
F
L
R
L
H
A
G
M
L
A
I
F
F
E
N
D
A
H
A
L
R
F
Y
--
G
E
S
F
E
K
Y
R
E
E
P
I
F
K
A
V
V
K
A
P
K
G
L
I
K
L
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
59.56
22%
-75
* C6 *
1JOP
3
Y227_HAEIN
A:
[1-155]
-------------------------------------------------------------------------------------------------------------------------------
M
I
I
S
S
L
--
T
N
P
N
F
K
V
G
L
P
K
V
I
A
--
E
V
C
D
Y
L
N
T
L
D
L
N
A
L
E
N
G
R
H
D
I
N
D
Q
I
Y
M
N
V
M
----------------------------
E
P
K
A
E
L
H
H
E
Y
L
D
V
Q
V
L
---
I
R
G
T
E
N
------
I
E
V
G
A
T
-
Y
P
N
L
S
K
Y
-
E
D
Y
N
E
A
D
D
Y
Q
L
C
A
D
I
D
D
K
F
T
V
T
M
K
P
K
M
F
A
V
F
Y
P
Y
E
P
H
K
P
C
C
-------------
V
I
K
K
L
V
V
K
V
P
V
K
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
59.00
20%
-92
- C6 -
1S4C
2
Y227_HAEIN
A:
[1-155]
-------------------------------------------------------------------------------------------------------------------------------
M
I
I
S
S
L
--
T
N
P
N
F
K
V
G
L
P
K
V
I
A
--
E
V
C
D
Y
L
N
T
L
---------
D
L
N
A
L
E
N
G
---
R
H
D
I
N
D
Q
I
Y
M
N
V
M
-
E
P
E
T
A
E
-------
P
S
S
K
K
A
E
L
H
H
E
Y
L
D
V
Q
V
L
---
I
R
G
T
E
N
------
I
E
V
G
-
A
T
Y
P
N
L
S
K
Y
-
E
D
Y
N
E
A
D
D
Y
Q
L
C
A
D
I
D
D
K
F
T
V
T
M
K
P
K
M
F
A
V
F
Y
P
Y
E
P
H
K
P
C
C
V
-----------
E
K
I
K
K
L
V
V
K
V
P
V
K
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
44.79
25%
-40
- C5 -
2IYP
-
6PGD_LACLM
A:
[374-454]
------------------------------------------------------------------------------------------------------------------------------------
L
--
Q
N
I
T
D
A
F
D
K
D
S
E
L
E
NL
L
L
D
D
Y
F
V
D
I
T
K
R
Y
Q
E
A
V
R
D
V
V
S
L
A
V
Q
A
G
T
P
I
P
T
F
T
S
A
I
S
Y
Y
D
-
S
Y
R
S
E
N
L
P
A
N
L
I
Q
A
Q
R
D
Y
F
G
A
H
T
Y
E
R
T
D
K
A
G
---
I
F
H
Y
D
W
------
Y
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
44.47
25%
-45
- C6 -
1JOP
3
Y227_HAEIN
A:
[63-130]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
H
H
E
Y
L
D
V
Q
V
L
---
I
R
G
T
E
N
------
I
E
V
G
-
A
-
T
Y
P
N
L
S
K
Y
E
D
Y
N
E
A
D
D
Y
Q
L
C
A
D
I
D
D
K
F
T
V
T
M
K
P
K
M
F
A
V
F
Y
P
Y
E
P
H
K
P
C
C
V
--
I
K
K
L
V
V
K
V
P
V
K
L
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
44.29
25%
-48
- C5 -
2IYO
1
6PGD_LACLM
A:
[373-453]
------------------------------------------------------------------------------------------------------------------------------------
L
--
Q
N
I
T
D
A
F
D
K
D
S
E
L
E
NL
L
L
D
D
Y
F
V
D
I
T
K
R
Y
Q
E
A
V
R
D
V
V
S
L
A
V
Q
A
G
T
P
I
P
T
F
T
S
A
I
S
Y
Y
D
-
S
Y
R
S
E
N
L
P
A
N
L
I
Q
A
Q
R
D
Y
F
G
A
H
T
Y
E
R
T
D
K
A
G
---
I
F
H
Y
D
W
------
Y
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
44.09
25%
-48
- C5 -
2IZ1
1
6PGD_LACLM
A:
[375-455]
------------------------------------------------------------------------------------------------------------------------------------
L
--
Q
N
I
T
D
A
F
D
K
D
S
E
L
E
NL
L
L
D
D
Y
F
V
D
I
T
K
R
Y
Q
E
A
V
R
D
V
V
S
L
A
V
Q
A
G
T
P
I
P
T
F
T
S
A
I
S
Y
Y
D
-
S
Y
R
S
E
N
L
P
A
N
L
I
Q
A
Q
R
D
Y
F
G
A
H
T
Y
E
R
T
D
K
A
G
---
I
F
H
Y
D
W
------
Y
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
43.92
25%
-49
- C5 -
2IZ0
-
6PGD_LACLM
A:
[375-455]
------------------------------------------------------------------------------------------------------------------------------------
L
--
Q
N
I
T
D
A
F
D
K
D
S
E
L
E
NL
L
L
D
D
Y
F
V
D
I
T
K
R
Y
Q
E
A
V
R
D
V
V
S
L
A
V
Q
A
G
T
P
I
P
T
F
T
S
A
I
S
Y
Y
D
-
S
Y
R
S
E
N
L
P
A
N
L
I
Q
A
Q
R
D
Y
F
G
A
H
T
Y
E
R
T
D
K
A
G
---
I
F
H
Y
D
W
------
Y
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
42.86
25%
-35
- C6 -
1S4C
2
Y227_HAEIN
A:
[63-130]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
H
H
E
Y
L
D
V
Q
V
L
---
I
R
G
T
E
N
------
I
E
V
G
-
A
-
T
Y
P
N
L
S
K
Y
E
D
Y
N
E
A
D
D
Y
Q
L
C
A
D
I
D
D
K
F
T
V
T
M
K
P
K
M
F
A
V
F
Y
P
Y
E
P
H
K
P
C
C
V
--
E
K
I
K
K
L
V
V
K
V
P
V
K
L
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
38.92
14%
-24
- C1 -
1FTR
-
FTR_METKA
A:
[1-148]
------------------------------------------------------------------------------------------------------------------------------
M
E
I
N
G
V
E
I
E
D
T
F
A
E
A
F
E
A
K
M
A
R
V
--
L
I
T
A
A
S
H
K
W
A
M
I
A
V
K
E
A
T
G
F
G
T
S
V
I
M
C
P
A
E
A
G
I
D
C
G
Y
V
P
P
E
E
-
T
P
------------------
D
G
R
P
G
V
T
I
M
I
G
H
ND
E
D
E
L
K
E
------
Q
L
L
D
-
R
-
I
G
Q
C
V
M
T
-
A
P
-----
T
A
S
A
F
D
A
M
P
E
A
E
---------
K
E
D
E
D
R
V
G
Y
K
L
S
F
F
--
G
D
G
Y
Q
-
E
E
D
E
L
D
G
R
K
V
W
K
I
P
V
V
E
G
E
F
I
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
38.62
18%
-38
- C5 -
2I3O
-
?
D:
[2-516]
FRSRPNALSQRSVIASSSELASLAGRDILKRGGNIFDAALAVSALCVTQNNLCGLGGDLFALIRDENGQIDLNGSGQASRAVSIDYYESGLTKIPERGPYAAITVPGIAGSWDEIFRKFATDIADI
L
E
P
A
I
R
T
--
A
S
A
G
--------
F
P
--
I
T
Q
N
Y
S
D
S
I
A
R
S
A
P
V
I
G
Q
Y
R
G
W
S
S
I
F
P
N
G
S
V
P
V
A
G
E
I
L
K
Q
P
D
L
A
E
S
F
R
L
S
E
----
E
G
F
R
S
F
Y
D
G
----
S
L
A
D
I
I
---
I
A
G
L
E
G
TGSPLS
D
R
D
L
-
R
-
V
Y
R
P
L
I
G
-
K
P
V
F
T
D
L
D
E
F
R
I
Y
E
T
S
P
N
S
Q
----
G
I
T
V
I
E
W
I
R
G
E
S
H
--
G
Y
D
--
S
R
T
W
E
-
A
K
I
E
D
I
F
E
T
----
E
E
A
Y
D
K
R
R
K
ITDPSYNIAQHDSANGKGLPKRDHNDIGDTTYFSISDSEGRSVSIIQSNYGFGSGIVPKGTGFVLQNRGSYFTLQRDHPNALPGKRTFHTLAACVEKEHDLYASLGSGGDIQPQVQQILEILKDNTDPQAILDKPRWTEPYTIYEAPGAVYVESEELYRNVSKQISGRKVVLRDVSQEFGTAQITTLIRGDVVVGAADPRGDGIAIPYS
27
Fugue
38.43
25%
-49
* C5 *
2XF7
-
?
A:
[3-50]
---------------------------------------------------------------------------------------------------------------------------------------------------
E
S
--
L
L
Y
G
Y
F
L
D
S
W
L
D
G
T
-
A
S
E
E
L
L
R
V
A
V
N
A
--------
G
D
L
T
Q
E
E
-
A
D
K
I
M
S
Y
P
----
W
G
A
W
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
37.30
9%
-42
- C2 -
3O9X
2
MQSA_ECOLI
A:
[2-133]
-------------------------------------------------------------------------------------------------------------------------------
H
M
K
C
P
V
--
C
H
Q
G
E
M
V
S
G
I
K
D
I
P
--
Y
T
F
R
G
R
K
T
V
L
K
G
------------------
I
H
G
L
Y
C
V
H
C
E
E
S
-
I
M
N
K
E
E
S
D
----
A
F
M
A
Q
V
K
A
F
R
A
S
V
N
A
E
T
V
--------
A
P
------
E
F
I
V
-
K
-
V
R
K
K
------------------------
L
S
L
T
Q
K
E
A
S
E
I
F
G
G
G
V
N
A
F
S
R
Y
E
K
G
N
A
Q
P
H
P
S
T
I
K
L
L
R
V
L
D
K
H
P
E
L
L
N
E
I
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
32.02
17%
-18
- C6 -
1ZVF
1
3HAO_YEAST
A:
[46-103]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
D
Y
H
I
N
P
-
T
P
E
W
F
Y
Q
---
K
K
G
S
M
L
------
L
K
V
V
-
D
-
E
T
D
-------
A
---------
E
P
K
--
F
I
D
I
I
I
N
E
G
D
S
Y
L
L
P
G
N
V
P
H
S
P
V
R
F
--
A
D
T
V
G
I
V
V
E
Q
D
R
P
G
G
E
N
D
K
I
R
W
Y
C
S
H
C
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
30.10
9%
-15
- C6 -
2PHL
1
PHSB_PHAVU
A:
[257-311]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
S
K
A
I
V
I
L
V
V
---
N
E
G
E
A
H
------
V
E
L
V
-
G
-
P
K
G
--
E
T
-
L
E
Y
-------------
E
S
Y
R
A
E
L
S
K
D
D
V
F
V
I
P
A
A
Y
P
V
A
I
K
A
T
--
S
N
V
N
F
T
G
F
G
I
N
A
N
N
N
N
R
N
L
L
A
G
K
T
D
N
V
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
28.16
6%
-31
- C6 -
3GBG
1
TCPN_VIBC3
A:
[24-71]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
Y
I
N
-
D
Y
K
M
F
W
I
---
D
S
G
I
A
K
------
L
I
D
K
-
N
-
C
------------------------
L
V
S
Y
E
I
N
S
S
S
I
I
L
L
K
K
N
S
I
Q
R
F
S
L
T
--
S
L
S
D
E
N
I
N
V
S
V
I
T
I
S
D
S
F
I
R
S
L
K
S
Y
I
L
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
27.26
23%
88
- C5 -
1CKX
-
A:
[1-26]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
P
G
T
I
K
E
N
I
I
F
--
G
V
S
Y
D
E
Y
R
Y
R
S
V
I
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
26.79
13%
6
- C6 -
2Y0O
3
DLYKI_BACSU
A:
[79-142]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
Q
E
T
F
R
C
---
R
Y
G
K
V
Y
------
L
Y
V
E
-
G
-
E
K
T
-
P
L
P
-
K
V
L
P
P
Q
E
D
R
E
H
Y
T
V
---
W
H
E
I
E
L
E
P
G
G
Q
Y
T
I
P
P
N
T
K
H
W
F
Q
A
G
--
E
E
G
A
V
V
T
E
M
S
S
T
S
T
D
K
H
D
I
F
T
D
P
R
I
L
E
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------