@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0466: (2015-12-15 )
MKTKAGFVALIGKPNAGKSTLLNTLLNAHLALVSHKANATRKLMKCIVPFKDKEGYESQIIFLDTPGLHHQEKLLNQCMLSQALKAMGDAELRVFLASVHDDLKGYEEFLSLCQKPHILALSKIDTATHKQVLQKLQEYQKYSSQFLALVPLSAKKSQNLNALLECISKHLSPSAWLFEKDLMSDEKMRDIYKEIIRESLFDFLSDEIPYESDVMIDKFIEEERIDKVYARIIVEKESQKKIVIGKNGVNIKRIGTNARLKMQEVGEKKVFLNLQVIAQKSWSKEEKSLQKLGYIYQRNRD
Atome Classification :
(20 SA)
.........10........20........30........40........50------------------.....-...60.......-----.70----...--......80........90.....------...100----...--.-----..--..-----110.---..--------..----.------.120...-....130........140....--..----.150.......160.......170..------------.....180.-......190.......200.......210......--.220.---.-..-...230.......240.......250.......260.......270.......280........290.......300----------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKTKA
G
F
V
A
L
IGKPNA
G
K
S
T
L
L
N
T
L
L
N
A
H
L
A
L
V
SHK
A
N
A
T
R
K
L
M
K
C
IVPFK------------------DKEGY-E
S
Q
I
I
F
L
DTPGL-----
H
H
-----
Q
E
K
--
L
L
N
Q
C
M
L
S
Q
A
L
K
AMG
D
A
E
L
R
V
F
L
------
A
S
V
H
D
-----
D
L
K
--
G
-----
Y
E
--
E
F
-----
L
S
L
C---QK--------P
H
----
I
------
L
A
L
S
KID-
T
A
T
H
K
Q
-
V
L
Q
K
L
Q
E
Y
Q
K
Y
S
S
Q
F
--
L
A
----
L
VPLSAKKSQ
N
L
N
A
L
L
E
C
I
S
K
HLSPS------------
A
W
L
F
E
K
D
LM-S
D
E
K
M
R
D
I
Y
K
E
I
I
R
E
S
L
F
D
F
L
S
DEIPYES
D
V
M
I
D
K
--
F
I
E
E
E
---
R
-
I
D
-
K
V
Y
A
R
I
IVEKESQ
K
K
I
V
IGKNG
V
N
I
K
R
IGTNA
R
L
K
M
Q
EVGE
K
K
V
F
L
N
L
Q
V
I
A
QK-SW
S
K
E
E
K
S
L
Q
K
L
G
Y
I
Y
QRNRD-----------------------------------------------------------------------
3
PsiBlast_PDB
79.93
37%
-97
- C1 -
3IEU
7
ERA_ECOLI
A:
[5-296]
-
K
S
Y
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
---
R
I
V
G
I
H
------------------
T
E
G
A
Y
---
Q
A
I
Y
V
D
T
P
G
L
-----
H
M
-----
E
E
K
R
-
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
------
V
E
G
T
R
-----
W
T
P
--
D
-----
D
E
--
M
V
-----
L
N
K
L
---
R
E
G
K
A
-----
P
V
----
I
------
L
A
V
N
K
V
D
-
N
V
Q
E
K
A
-
D
L
L
P
H
L
Q
F
L
A
S
Q
M
N
F
--
L
D
----
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
------------
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
--
F
V
S
N
E
---
R
-
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
-
G
W
A
D
D
E
R
A
L
R
S
L
G
-------------------------------------------------------------------------------
61
HHSearch
79.90
39%
-102
- C1 -
1EGA
3
ERA_ECOLI
A:
[5-295]
-
K
S
Y
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
E
G
------------------------
A
Y
Q
A
I
Y
V
D
T
P
G
L
-----
H
M
-----
E
E
K
R
-
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
------
V
E
G
T
R
-----
W
T
P
--
D
-----
D
E
--
M
V
L
N
K
--
L
R
E
G
---
K
A
--------
P
V
----
I
------
L
A
V
N
K
V
D
-
N
V
Q
E
K
A
D
L
L
P
H
L
Q
F
L
A
S
-
Q
M
N
F
--
L
D
----
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
------------
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
--
F
V
S
N
E
R--
G
-
G
Y
-
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
-
G
W
A
D
D
E
R
A
L
R
S
L
--------------------------------------------------------------------------------
21
PsiBlast_CBE
79.61
37%
-98
- C1 -
3IEU
9
ERA_ECOLI
B:
[5-296]
-
K
S
Y
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
---
R
I
V
G
I
H
------------------
T
E
G
A
Y
---
Q
A
I
Y
V
D
T
P
G
L
-----
H
M
-----
E
E
K
R-
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
------
V
E
G
T
R
-----
W
T
P
--
D
-----
D
E
--
M
V
-----
L
N
K
L
---
R
E
GKA-----
P
V
----
I
------
L
A
V
N
K
V
D
-
N
V
Q
E
K
A
-
D
L
L
P
H
L
Q
F
L
A
S
Q
M
N
F
--
L
D
----
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
------------
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
--
F
V
S
N
E
---
R
-
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
-
G
W
A
D
D
E
R
A
L
R
S
L
G
-------------------------------------------------------------------------------
5
PsiBlast_PDB
78.79
32%
-94
- C1 -
3R9W
8
ERA_AQUAE
A:
[8-305]
---
K
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
------------------
N
-----
E
A
Q
I
I
F
L
D
T
P
G
I
-----
Y
E
-----
P
K
K
SD
V
L
G
H
S
M
V
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
------
I
D
A
T
E
GWR
P
R
D
E
E
--
I
-----
Y
Q
--
N
F
-----
I
K
P
L
---
N
K
--------
P
V
----
I
------
V
V
I
N
K
I
D
K
I
G
P
A
K
N
-
V
L
P
L
I
D
E
I
H
K
K
H
P
E
L
--
T
E
----
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
------------
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
--
I
K
P
G
D
ANP
N
-
M
L
-
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
-
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
L
----------------------------------------------------------------------------
1
PsiBlast_PDB
78.77
37%
-101
- C1 -
1EGA
3
ERA_ECOLI
A:
[5-295]
-
K
S
Y
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
---
R
I
V
G
I
H
------------------
T
E
G
A
Y
---
Q
A
I
Y
V
D
T
P
G
L
-----
H
M
-----
E
E
K
R
-
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
------
V
E
G
T
R
-----
W
T
P
--
D
-----
D
E
--
M
V
-----
L
N
K
L
---
R
E
GK
A
-----
P
V
----
I
------
L
A
V
N
K
V
D
-
N
V
Q
E
K
A
-
D
L
L
P
H
L
Q
F
L
A
S
Q
M
N
F
--
L
D
----
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
------------
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
--
F
V
S
N
E
---
R
-
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
-
G
W
A
D
D
E
R
A
L
R
S
L
--------------------------------------------------------------------------------
7
PsiBlast_PDB
78.67
32%
-93
- C1 -
3IEV
4
ERA_AQUAE
A:
[9-306]
---
K
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
------------------
N
-----
E
A
Q
I
I
F
L
D
T
P
G
I
-----
Y
E
-----
P
K
K
SD
V
L
G
H
S
M
V
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
------
I
D
A
T
E
-----
G
W
R
--
P
R
D
E
E
I
Y
Q
--
N
F
-----
I
K
P
L
---
N
K
--------
P
V
----
I
------
V
V
I
N
K
I
D
K
I
G
P
A
K
N
-
V
L
P
L
I
D
E
I
H
K
K
H
P
E
L
--
T
E
----
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
------------
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
--
I
K
P
G
D
ANP
N
-
M
L
-
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
-
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
L
----------------------------------------------------------------------------
22
PsiBlast_CBE
78.62
37%
-98
- C1 -
1EGA
2
ERA_ECOLI
B:
[5-296]
-
K
S
Y
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
---
R
I
V
G
I
H
------------------
T
E
G
A
Y
---
Q
A
I
Y
V
D
T
P
G
L
-----
H
M
-----
E
E
K
R-
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
------
V
E
G
T
R
-----
W
T
P
--
D
-----
D
E
--
M
V
-----
L
N
K
L
---
R
E
GKA-----
P
V
----
I
------
L
A
V
N
K
V
D
-
N
V
Q
E
K
A
-
D
L
L
P
H
L
Q
F
L
A
S
Q
M
N
F
--
L
D
----
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
------------
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
--
F
V
S
N
E
---
R
-
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
-
G
W
A
D
D
E
R
A
L
R
S
L
G
-------------------------------------------------------------------------------
6
PsiBlast_PDB
78.58
32%
-93
- C1 -
3R9X
4
ERA_AQUAE
A:
[8-305]
---
K
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
------------------
N
-----
E
A
Q
I
I
F
L
D
T
P
G
I
-----
Y
E
-----
P
K
K
SD
V
L
G
H
S
M
V
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
------
I
D
A
T
E
GWR
P
R
D
E
E
--
I
-----
Y
Q
--
N
F
-----
I
K
P
L
---
N
K
--------
P
V
----
I
------
V
V
I
N
K
I
D
K
I
G
P
A
K
N
-
V
L
P
L
I
D
E
I
H
K
K
H
P
E
L
--
T
E
----
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
------------
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
--
I
K
P
G
D
ANP
N
-
M
L
-
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
-
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
L
----------------------------------------------------------------------------
63
HHSearch
76.98
33%
-87
- C1 -
3IEV
4
ERA_AQUAE
A:
[7-307]
-
H
M
K
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
----------------------
N
-
E
A
Q
I
I
F
L
D
T
P
G
I
-----
Y
E
-----
P
K
K
SD
V
L
G
H
S
M
V
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
------
I
D
A
T
E
-----
G
W
R
--
P
-----
R
D
--
E
E
I
Y
Q
N
F
I
K
P
L
---
N
K
--------
P
V
----
I
------
V
V
I
N
K
I
D
-
K
I
G
P
A
K
N
V
L
P
L
I
D
E
I
H
K
K
H
P
E
L
--
T
E
----
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
------------
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
--
I
K
P
G
D
ANP
N
-
M
L
-
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
-
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
L
----------------------------------------------------------------------------
62
HHSearch
73.05
32%
-80
- C1 -
1WF3
4
ERA_THET8
A:
[4-298]
-
K
T
Y
S
G
F
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
V
K
V
A
P
I
S
P
R
P
Q
T
T
R
K
R
L
R
G
I
L
T
E
G
------------------------
R
R
Q
I
V
F
V
D
T
P
G
L
-----
H
K
-----
P
M
D
--
A
L
G
E
F
M
D
Q
E
V
Y
E
A
L
A
D
V
N
A
V
V
W
V
------
V
D
L
R
H
-----
P
P
T
--
P
-----
E
D
--
E
L
V
A
R
A
-
L
K
P
L
VG-
K
V
--------
P
I
----
L
------
L
V
G
N
K
L
D
-
A
A
K
Y
P
E
E
A
M
K
A
Y
H
E
----
L
L
P
E
--
A
E
----
P
R
M
L
S
A
L
D
E
R
Q
V
A
E
L
K
A
D
L
L
A
L
M
P
E
G
------------
P
F
F
Y
P
E
D
Y
A
K
S
D
Q
T
F
G
E
W
V
A
E
I
L
R
E
E
A
M
K
R
L
W
H
E
V
P
Y
A
V
A
T
K
V
E
E
--
V
A
E
R
E
N--
G
-
V
L
-
Y
I
K
A
I
L
Y
V
E
R
P
S
Q
K
A
I
V
I
G
E
G
G
R
K
I
K
E
I
G
Q
A
T
R
K
Q
L
E
A
L
L
G
K
K
V
Y
L
D
L
E
V
K
V
Y
P
-
D
W
R
K
D
P
E
A
L
R
E
L
G
Y
R
S
----------------------------------------------------------------------------
8
PsiBlast_PDB
67.99
31%
-63
- C1 -
1WF3
4
ERA_THET8
A:
[4-296]
-
K
T
Y
S
G
F
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
V
K
V
A
P
I
S
P
R
P
Q
T
T
R
K
R
L
R
G
I
L
----------------------
T
E
G
--
R
R
Q
I
V
F
V
D
T
P
G
L
-----
H
K
-----
P
M
D
--
A
L
G
E
F
M
D
Q
E
V
Y
E
A
L
A
D
V
N
A
V
V
W
V
------
V
D
L
R
H
-----
P
P
T
--
P
-----
E
D
--
E
L
-----
V
A
R
A
---
L
K
--------
P
L
----
V
GK
V
P
I
L
L
V
G
N
K
L
D
-
A
A
K
Y
P
E
-
E
A
M
K
A
Y
H
E
L
L
P
E
A
E
P
--
R
M
----
L
S
A
L
D
E
R
Q
V
A
E
L
K
A
D
L
L
A
L
---
M
P
E
G
------------
P
F
F
Y
P
E
D
Y
A
K
S
D
Q
T
F
G
E
W
V
A
E
I
L
R
E
E
A
M
K
R
L
W
H
E
V
P
Y
A
V
A
T
K
V
E
E
--
V
A
E
R
E
---
N
G
V
L
-
Y
I
K
A
I
L
Y
V
E
R
P
S
Q
K
A
I
V
I
G
E
G
G
R
K
I
K
E
I
G
Q
A
T
R
K
Q
L
E
A
L
L
G
K
K
V
Y
L
D
L
E
V
K
V
Y
P
-
D
W
R
K
D
P
E
A
L
R
E
L
G
Y
R
S
----------------------------------------------------------------------------
2
PsiBlast_PDB
59.56
37%
120
- C- -
1X1L
-
ERA_THET8
X:
[5-295]
-
K
S
Y
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
---
R
I
V
G
I
H
------------------
T
E
G
A
Y
---
Q
A
I
Y
V
D
T
P
G
L
-----
H
M
-----
E
E
K
R-
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
------
V
E
G
T
R
-----
W
T
P
--
D
-----
D
E
--
M
V
-----
L
N
K
L
---
R
E
GKA-----
P
V
----
I
------
L
A
V
N
K
V
D
-
N
V
Q
E
K
A
-
D
L
L
P
H
L
Q
F
L
A
S
Q
M
N
F
--
L
D
----
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
------------
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
--
F
V
S
N
E
---
R
-
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
-
G
W
A
D
D
E
R
A
L
R
S
L
--------------------------------------------------------------------------------
15
PsiBlast_PDB
59.39
28%
-114
- C1 -
3PR1
1
ENGB_THEMA
A:
[24-192]
-----
G
E
V
A
F
V
G
R
S
N
V
G
K
S
S
L
L
N
A
L
F
N
-------------
R
S
I
N
F
Y
L
V
---------------------------
N
S
K
Y
Y
F
V
D
L
P
G
Y
------------
K
E
R
--
M
L
W
K
R
L
V
E
D
Y
F
K
N
R
W
S
L
Q
M
-
V
F
L
L
V
DGRI
P
P
Q
D
S
-----
D
L
M
--
M
-----
V
E
--
W
M
-----
K
S
L
----
N
I
--------
P
F
----
T
------
I
V
L
T
K
M
D
-
K
V
K
M
S
E
-
R
A
K
K
L
E
E
H
R
K
V
F
S
K
Y
GE
Y
T
----
I
I
P
T
S
S
V
T
G
E
G
I
S
E
L
L
D
L
I
S
T
L
L
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
Fugue
58.82
33%
-112
- C1 -
1EGA
3
ERA_ECOLI
A:
[4-182]
D
K
S
Y
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
E
G
------------------
A
------
Y
Q
A
I
Y
V
D
T
P
G
L
H----
M
E
-----
E
K
R
--
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
------
V
E
G
T
R
-----
W
T
P
--
D
-----
D
E
--
M
V
-----
L
N
K
L
REG
K
A
--------
P
V
----
I
------
L
A
V
N
K
V
D
-
N
V
Q
E
K
A
-
D
L
L
P
H
L
Q
F
L
A
S
Q
M
N
F
--
L
D
----
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
------------
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
--
F
V
S
N
E
---
R
-
G
G
-
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
-
S
G
W
A
D
D
E
R
A
L
R
S
L
-------------------------------------------------------------------------------
14
PsiBlast_PDB
58.81
28%
-106
- C1 -
3PQC
2
ENGB_THEMA
A:
[24-192]
-----
G
E
V
A
F
V
G
R
S
N
V
G
K
S
S
L
L
N
A
L
F
N
R
K
I
A
F
V
S
K
T
P
G
K
T
R
S
I
N
F
Y
L
V
---------------------------
N
S
K
Y
Y
F
V
D
L
P
G
Y
-----
G
Y
AKVS
K
K
E
R
--
M
L
W
K
R
L
V
E
D
Y
F
K
N
R
W
S
L
Q
M
-
V
F
L
L
V
DGRI
P
P
Q
D
S
-----
D
L
M
--
M
-----
V
E
--
W
M
-----
K
S
L
----
N
I
--------
P
F
----
T
------
I
V
L
T
K
M
D
-
K
V
K
M
S
E
-
R
A
K
K
L
E
E
H
R
K
V
F
S
K
Y
GE
Y
T
----
I
I
P
T
S
S
V
T
G
E
G
I
S
E
L
L
D
L
I
S
T
L
L
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
58.65
30%
-109
- C1 -
2DYK
1
?
A:
[4-161]
-------
V
V
I
V
G
R
P
N
V
G
K
S
S
L
F
N
R
L
L
K
K
R
S
-----------
D
L
K
E
G
V
V
-----------------------
E
T
D
-
R
G
R
F
L
L
V
D
T
G
G
L
-----
W
S
-----
G
D
K
---
W
E
K
K
I
Q
E
K
V
D
R
A
L
E
D
A
E
V
V
L
F
A
------
V
D
G
R
A
-----
E
L
T
Q
A
D
-----
Y
E
V
A
E
Y
-----
L
R
R
K
---
G
K
--------
P
V
----
I
------
L
V
A
T
K
V
D
-
D
P
K
H
E
L
-
Y
L
G
P
L
-----
Y
G
L
G
F
--
G
D
----
P
I
P
T
S
S
E
H
A
R
G
L
E
E
L
L
E
A
I
W
E
R
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
58.28
37%
132
- C- -
1X18
2
ERA_THET8
X:
[2-292]
-
K
S
Y
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
---
R
I
V
G
I
H
------------------
T
E
G
A
Y
---
Q
A
I
Y
V
D
T
P
G
L
-----
H
M
-----
E
E
K
R-
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
------
V
E
G
T
R
-----
W
T
P
--
D
-----
D
E
--
M
V
-----
L
N
K
L
---
R
E
GKA-----
P
V
----
I
------
L
A
V
N
K
V
D
-
N
V
Q
E
K
A
-
D
L
L
P
H
L
Q
F
L
A
S
Q
M
N
F
--
L
D
----
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
------------
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
--
F
V
S
N
E
---
R
-
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
-
G
W
A
D
D
E
R
A
L
R
S
L
--------------------------------------------------------------------------------
19
PsiBlast_PDB
58.07
30%
-115
- C1 -
2E87
1
?
A:
[170-338]
-------
V
V
I
A
G
H
P
N
V
G
K
S
T
L
L
K
A
L
T
T
A
K
P
E
I
A
S
Y
P
F
-
T
T
R
G
I
--
N
V
G
Q
F
E
------------------
D
--
G
Y
F
R
Y
Q
I
I
--
D
T
P
G
L
LDRPI
S
E
-----
R
N
E
--
I
E
K
Q
A
I
L
--
A
L
R
Y
L
G
N
L
I
I
Y
I
F
D
------
P
S
E
H
C
-----
G
F
P
--------
L
E
--
E
Q
-----
I
H
L
F
---
E
E
V
H
G
E
F
KD
L
P
F
----
L
------
V
V
I
N
K
I
D
-
V
A
D
E
E
N
-
I
-
K
R
L
E
K
F
V
K
--
E
K
G
--
L
N
----
P
I
K
I
S
A
L
K
G
T
G
I
D
L
V
K
E
E
I
I
K
T
L
R
P
L
------------
A
E
K
V
A
R
E
K
I
-
E
R
E
L
R
R
Y
R
S
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
Fugue
57.11
17%
-46
- C1 -
1KK1
3
IF2G_PYRAB
A:
[6-410]
S
R
Q
A
E
V
N
I
G
M
V
G
H
V
D
H
G
K
T
T
L
T
K
A
L
T
G
V
W
T
D
S
E
E
L
R
R
G
I
T
I
K
I
G
F
A
D
A
E
I
R
R
C
PNCGRYSTSPVCPYCG
H
E
T
E
F
-
V
R
R
V
S
F
I
D
A
P
G
-------------
H
E
A
--
L
M
T
T
M
L
A
G
A
S
L
M
---
D
G
A
I
L
V
I
A
------
A
N
E
P
C
-----
P
R
P
--
Q
-----
T
R
--
E
H
-----
L
M
A
L
---
Q
I
--------
I
G
QKN
I
I
------
I
A
Q
N
K
I
E
-
L
V
D
K
E
K
-
A
L
E
N
Y
R
Q
I
K
E
F
I
E
G
T
--
V
A
EN
A
P
I
I
P
I
S
A
L
H
G
A
N
I
D
V
L
V
K
A
I
E
D
F
I
P
T
P
KRDPNKP
P
K
M
L
V
L
R
S
F
D
V
N
K
P
-
G
K
L
V
G
G
V
L
D
G
S
I
V
Q
G
K
L
K
--
V
G
D
E
I
E
I
R
P
G
V
P
Y
E
E
HG
R
I
K
Y
E
---
P
-
I
T
-
T
E
I
V
S
L
Q
A
G
G
Q
F
V
E
E
A
Y
P
G
G
L
------
V
G
V
G
T
K
L
D
P
Y
L
T
K
G
D
L
--
M
A
G
N
V
V
G
K
P
G
K
L
P
P
V
W
D
S
L
R
L
E
V
H
L
L
E
R
V
V
E
QELKVEPIKRK
E
V
L
L
L
N
V
GT
A
R
T
M
G
L
V
TGLGKD
E
I
E
V
K
L
Q
I
P
V
C
A
E
PG
D
R
V
A
I
S
R
Q
I
GS
R
W
R
L
I
G
Y
G
I
I
K
E
80
HHSearch
56.80
30%
-97
- C1 -
2DYK
1
?
A:
[2-160]
-----
H
K
V
V
I
V
G
R
P
N
V
G
K
S
S
L
F
N
R
L
L
K
K
R
S
-----------
D
L
K
E
G
V
V
E
T
D
------------------------
R
G
R
F
L
L
V
D
T
G
G
L
-----
W
S
-----
G
D
K
--
W
-
E
K
K
I
Q
E
K
V
D
R
A
L
E
D
A
E
V
V
L
F
A
------
V
D
G
R
A
-----
E
L
T
--
Q
-----
A
D
--
Y
E
V
A
E
Y
-
L
R
R
K
---
G
K
--------
P
V
----
I
------
L
V
A
T
K
V
D
-
D
P
K
H
E
L
-
Y
L
G
P
L
---
Y
G
--
L
G
F
--
G
D
----
P
I
P
T
S
S
E
H
A
R
G
L
E
E
L
L
E
A
I
W
E
R
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------