@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0561: (2015-12-16 )
MKQLFLIIGAPGSGKTTDAELIAKNNSETIAHFSTGDLLRAESAKKTERGLLIEKFTSQGELVPLEIVVETILSAIKSSSKGIILIDGYPRSVEQMQALDKELNAQNEVILKSVIEVEVSENTAKERVLGRSRGADDNERVFHNRMRVFLDPLVEIQNFYKAKHLHKIINGERSIEEIVNEMQKYILSFAN
Atome Classification :
(25 SA)
.........10........20........30........40...-.....50........60......---..70....-...---.---80..-......90........100.......110.......120.......130------------------------.------------------------------.------------------------------.--------------------------------.---..-..140.......150..---.....160.-.-----.....170.......180--.........190
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
Q
L
F
L
I
I
GAPGSGKTTD
A
E
L
I
AKNNS
E
T
I
A
HFSTGDL
L
R
A
ESA-KKTER
G
L
L
I
E
K
FTSQG
E
L
V
P
L
E
I
---
V
V
E
T
I
L
S
A
-
I
KS---S---SK
G
I
-
I
L
IDGYP
R
S
V
E
Q
M
Q
A
L
D
K
E
LNA
Q
N
E
V
I
L
K
S
V
I
E
V
E
VSEN
T
A
K
E
R
V
LGR-------------------------S------------------------------R------------------------------G--------------------------------A---DD-
N
E
R
V
F
H
N
R
M
R
V
F
L
D
P
L
V
---
E
I
Q
N
F
Y
K
A
K
-
H
-----
L
H
K
I
ING
E
R
S
I
E
E
I
V
N
----
E
M
Q
K
Y
I
L
S
FAN
100
HHSearch
89.72
31%
-102
- C1 -
3UMF
-
?
A:
[8-194]
K
A
K
V
I
F
V
L
G
G
P
G
S
G
K
G
T
Q
C
E
K
L
V
Q
K
F
--
H
F
N
H
L
S
S
G
D
L
L
R
A
E
V
Q
-
S
G
S
P
K
G
K
E
L
K
A
M
M
E
R
G
E
L
V
P
L
E
V
---
V
L
A
L
L
K
E
A
-
M
I
K
L
--
V
D--
K
N
C
H
-
F
L
I
D
G
Y
P
R
E
L
D
Q
G
I
K
F
E
K
E
V
-----
C
P
C
L
C
V
I
N
F
D
V
S
E
E
V
M
R
K
R
L
L
K
----------------------------------------------------------------------------------------
R
--------------------------------
V
---
D
D
-
N
E
E
T
I
V
K
R
F
R
T
F
N
E
L
T
K
---
P
V
I
E
H
Y
K
Q
Q
-
N
-----
K
V
I
T
I
D
A
S
G
T
V
D
A
I
F
D
----
K
V
N
H
E
L
Q
K
F
G
V
12
PsiBlast_PDB
89.60
32%
-96
- C1 -
3UMF
-
?
A:
[10-194]
--
K
V
I
F
V
L
G
G
P
G
S
G
K
G
T
Q
C
E
K
L
V
Q
K
F
H
--
F
N
H
L
S
S
G
D
L
L
R
A
E
V
Q
-
S
G
S
P
K
G
K
E
L
K
A
M
M
E
R
G
E
L
V
P
L
E
V
---
V
L
A
L
L
K
E
A
M
I
K
L
---
V
---
D
K
N
C
H
F
L
I
D
G
Y
P
R
E
L
D
Q
G
I
K
F
E
K
E
V
C
P
-----
C
L
C
V
I
N
F
D
V
S
E
E
V
M
R
K
R
L
L
K
----------------------------------------------------------------------------------------
R
--------------------------------
V
---
D
D
-
N
E
E
T
I
V
K
R
F
R
T
F
N
E
L
T
K
---
P
V
I
E
H
Y
K
Q
Q
-
N
-----
K
V
I
T
I
D
A
S
G
T
V
D
A
I
F
D
K
V
N
H
E
L
Q
K
F
G
V
K
---
26
PsiBlast_CBE
88.80
33%
-96
- C1 -
2BWJ
2
KAD5_HUMAN
E:
[13-194]
--
K
I
I
F
I
I
G
G
P
G
S
G
K
G
T
Q
C
E
K
L
V
E
K
Y
G
F
T
--
H
L
S
T
G
E
L
L
R
E
E
L
A
-
S
E
S
E
R
S
K
L
I
R
D
I
M
E
R
G
D
L
V
P
S
G
I
---
V
L
E
L
L
K
E
A
-
M
V
A
---
S
LGD
T
R
G
--
F
L
I
D
G
Y
P
R
E
V
K
Q
G
E
E
F
G
R
R
I
G
D
P
Q
L
V
I
C
-----
M
D
C
S
A
D
T
M
T
N
R
L
L
Q
M
-------------------------
S
------------------------------
R
------------------------------
S
--------------------------------
S
LPV
D
D
-
T
T
K
T
I
A
K
R
L
E
A
Y
Y
R
A
S
I
---
P
V
I
A
Y
Y
E
T
K
T
Q
-----
L
H
K
-
I
N
A
E
G
T
P
E
D
V
F
L
----
Q
L
C
T
A
I
D
S
I
F
-
6
PsiBlast_PDB
88.06
33%
-94
- C1 -
2BWJ
3
KAD5_HUMAN
A:
[13-194]
--
K
I
I
F
I
I
G
G
P
G
S
G
K
G
T
Q
C
E
K
L
V
E
K
Y
G
F
T
--
H
L
S
T
G
E
L
L
R
E
E
L
A
-
S
E
S
E
R
S
K
L
I
R
D
I
M
E
R
G
D
L
V
P
S
G
I
---
V
L
E
L
L
K
E
A
-
M
V
A
---
S
LGD
T
R
G
--
F
L
I
D
G
Y
P
R
E
V
K
Q
G
E
E
F
G
R
R
I
G
D
P
Q
L
V
I
C
-----
M
D
C
S
A
D
T
M
T
N
R
L
L
Q
M
-------------------------
S
------------------------------
R
------------------------------
S
--------------------------------
S
LP
V
D
D
-
T
T
K
T
I
A
K
R
L
E
A
Y
Y
R
A
S
I
---
P
V
I
A
Y
Y
E
T
K
T
Q
-----
L
H
K
-
I
N
A
E
G
T
P
E
D
V
F
L
----
Q
L
C
T
A
I
D
S
I
F
L
29
PsiBlast_CBE
88.05
33%
-95
- C1 -
2BWJ
4
KAD5_HUMAN
B:
[13-194]
--
K
I
I
F
I
I
G
G
P
G
S
G
K
G
T
Q
C
E
K
L
V
E
K
Y
G
F
T
--
H
L
S
T
G
E
L
L
R
E
E
L
A
-
S
E
S
E
R
S
K
L
I
R
D
I
M
E
R
G
D
L
V
P
S
G
I
---
V
L
E
L
L
K
E
A
-
M
V
A
---
S
LGD
T
R
G
--
F
L
I
D
G
Y
P
R
E
V
K
Q
G
E
E
F
G
R
R
I
G
D
P
Q
L
V
I
C
-----
M
D
C
S
A
D
T
M
T
N
R
L
L
Q
M
-------------------------
S
------------------------------
R
------------------------------
S
--------------------------------
S
LP
V
D
D
-
T
T
K
T
I
A
K
R
L
E
A
Y
Y
R
A
S
I
---
P
V
I
A
Y
Y
E
T
K
T
Q
-----
L
H
K
-
I
N
A
E
G
T
P
E
D
V
F
L
----
Q
L
C
T
A
I
D
S
I
F
L
25
PsiBlast_CBE
87.62
33%
-96
- C1 -
2BWJ
4
F:
[13-194]
--
K
I
I
F
I
I
G
G
P
G
S
G
K
G
T
Q
C
E
K
L
V
E
K
Y
G
F
T
--
H
L
S
T
G
E
L
L
R
E
E
L
A
-
S
E
S
E
R
S
K
L
I
R
D
I
M
E
R
G
D
L
V
P
S
G
I
---
V
L
E
L
L
K
E
A
-
M
V
A
---
S
LGD
T
R
G
--
F
L
I
D
G
Y
P
R
E
V
K
Q
G
E
E
F
G
R
R
I
G
D
P
Q
L
V
I
C
-----
M
D
C
S
A
D
T
M
T
N
R
L
L
Q
M
-------------------------
S
------------------------------
R
------------------------------
S
--------------------------------
S
LPV
D
D
-
T
T
K
T
I
A
K
R
L
E
A
Y
Y
R
A
S
I
---
P
V
I
A
Y
Y
E
T
K
T
Q
-----
L
H
K
-
I
N
A
E
G
T
P
E
D
V
F
L
----
Q
L
C
T
A
I
D
S
I
F
L
101
HHSearch
87.52
30%
-84
- C1 -
2XB4
2
?
A:
[1-222]
--
M
N
I
L
I
F
G
P
N
G
S
G
K
G
T
Q
G
N
L
V
K
D
K
Y
--
S
L
A
H
I
E
S
G
G
I
F
R
E
H
I
G
-
G
G
T
E
L
G
K
K
A
K
E
F
I
D
R
G
D
L
V
P
D
D
I
---
T
I
P
M
V
L
E
T
-
L
E
S
---
K
---
G
K
D
G
-
W
L
L
D
G
F
P
R
N
T
V
Q
A
Q
K
L
F
E
A
L
Q
E
-
K
G
M
K
I
N
F
V
I
E
I
L
L
P
R
E
V
A
K
N
R
I
M
G
R
-------------------------
R
------------------------------
I
------------------------------
C
KNNPN
H
P
N
N
IFIDA
I
K
P
NGDVCRVCG
G
A
L
S
A
R
A
---
D
D
Q
D
E
G
A
I
N
K
R
H
D
I
Y
Y
N
T
V
D
G
T
L
A
A
A
Y
Y
Y
K
N
M
-
A
AKEG
F
V
Y
I
E
L
D
G
E
G
S
I
D
S
I
K
D
----
T
L
L
A
Q
L
A
----
94
HHSearch
87.11
33%
-84
- C1 -
3TLX
4
?
A:
[29-242]
-
D
G
R
Y
I
F
L
G
A
P
G
S
G
K
G
T
Q
S
L
N
L
K
K
S
H
--
C
Y
C
H
L
S
T
G
D
L
L
R
E
A
A
E
-
K
K
T
E
L
G
L
K
I
K
N
I
I
N
E
G
K
L
V
D
D
Q
M
---
V
L
S
L
V
D
E
K
-
L
K
T
---
P
Q--
C
K
K
G
-
F
I
L
D
G
Y
P
R
N
V
K
Q
A
E
D
L
N
K
L
L
Q
K
-
N
Q
T
K
L
D
G
V
F
Y
F
N
V
P
D
E
V
L
V
N
R
I
S
G
R
-------------------------
L
------------------------------
I
HKPSG
R
I
Y
H
KIFNPPKVPFRDDVTN
E
P
L
I
Q
R
--------------------------------
E
---
D
D
-
N
E
D
V
L
K
K
R
L
T
V
F
K
S
E
T
S
---
P
L
I
S
Y
Y
K
N
K
-
N
-----
L
L
I
N
L
D
A
T
Q
P
A
N
D
L
E
K
----
K
I
S
Q
H
I
D
G
---
5
PsiBlast_PDB
87.09
31%
-81
- C1 -
4W5H
3
KAD_STRP2
A:
[8-216]
----
L
L
I
M
G
L
P
G
A
G
K
G
T
Q
A
A
K
I
V
E
Q
F
H
--
V
A
H
I
S
T
G
D
M
F
R
A
A
M
A
-
N
Q
T
E
M
G
V
L
A
K
S
Y
I
D
K
G
E
L
V
P
D
E
V
T
N
G
I
V
K
E
R
L
S
Q
-
D
D
I
---
K
---
E
T
G
F
-
L
L
-
D
G
Y
P
R
T
I
E
Q
A
H
A
L
D
K
T
L
-
A
E
L
G
I
E
L
E
G
I
I
N
I
E
V
N
P
D
S
L
L
E
R
L
S
G
R
I
I
H
RVTGETFHPVDYKEED
Y
-----
Y
------------------------------
Q
------------------------------
R
--------------------------------
E
---
D
D
-
K
P
E
T
V
K
R
R
L
D
V
N
I
A
Q
G
E
---
P
I
I
A
H
Y
R
A
K
-
G
-----
L
V
H
D
I
E
G
N
Q
D
I
N
D
V
F
S
----
D
I
E
K
V
L
T
N
L
--
27
PsiBlast_CBE
85.87
33%
-96
- C1 -
2BWJ
1
KAD5_HUMAN
D:
[13-194]
--
K
I
I
F
I
I
G
G
P
G
S
G
K
G
T
Q
C
E
K
L
V
E
K
Y
G
F
T
--
H
L
S
T
G
E
L
L
R
E
E
L
A
-
S
E
S
E
R
S
K
L
I
R
D
I
M
E
R
G
D
L
V
P
S
G
I
---
V
L
E
L
L
K
E
A
-
M
V
A
---
S
LGD
T
R
G
--
F
L
I
D
G
Y
P
R
E
V
K
Q
G
E
E
F
G
R
R
I
G
D
P
Q
L
V
I
C
-----
M
D
C
S
A
D
T
M
T
N
R
L
L
Q
M
-------------------------
S
------------------------------
R
------------------------------
S
--------------------------------
S
LPV
D
D
-
T
T
K
T
I
A
K
R
L
E
A
Y
Y
R
A
S
I
---
P
V
I
A
Y
Y
E
T
K
T
Q
-----
L
H
K
-
I
N
A
E
G
T
P
E
D
V
F
L
----
Q
L
C
T
A
I
D
S
I
--
28
PsiBlast_CBE
85.81
33%
-92
- C1 -
2BWJ
3
KAD5_HUMAN
C:
[13-194]
--
K
I
I
F
I
I
G
G
P
G
S
G
K
G
T
Q
C
E
K
L
V
E
K
Y
G
F
T
--
H
L
S
T
G
E
L
L
R
E
E
L
A
-
S
E
S
E
R
S
K
L
I
R
D
I
M
E
R
G
D
L
V
P
S
G
I
---
V
L
E
L
L
K
E
A
-
M
V
A
---
S
LGD
T
R
G
--
F
L
I
D
G
Y
P
R
E
V
K
Q
G
E
E
F
G
R
R
I
G
D
P
Q
L
V
I
C
-----
M
D
C
S
A
D
T
M
T
N
R
L
L
Q
M
-------------------------
S
------------------------------
R
------------------------------
S
--------------------------------
S
LP
V
D
D
-
T
T
K
T
I
A
K
R
L
E
A
Y
Y
R
A
S
I
---
P
V
I
A
Y
Y
E
T
K
T
Q
-----
L
H
K
-
I
N
A
E
G
T
P
E
D
V
F
L
----
Q
L
C
T
A
I
D
S
I
F
-
104
HHSearch
85.04
28%
-97
- C1 -
1ZD8
-
KAD3_HUMAN
A:
[6-215]
-
L
L
R
A
V
I
M
G
A
P
G
S
G
K
G
T
V
S
S
R
I
T
T
H
F
--
E
L
K
H
L
S
S
G
D
L
L
R
D
N
M
L
-
R
G
T
E
I
G
V
L
A
K
A
F
I
D
Q
G
K
L
I
P
D
D
V
---
M
T
R
L
A
L
H
E
-
L
K
N
---
L
---
T
Q
Y
S
-
W
L
L
D
G
F
P
R
T
L
P
Q
A
E
A
L
D
R
A
Y
------
Q
I
D
T
V
I
N
L
N
V
P
F
E
V
I
K
Q
R
L
T
A
R
-------------------------
W
------------------------------
I
HPASG
R
V
Y
N
IEFNPPKTVGIDDLTG
E
P
L
I
Q
R
--------------------------------
E
---
D
D
-
K
P
E
T
V
I
K
R
L
K
A
Y
E
D
Q
T
K
---
P
V
L
E
Y
Y
Q
K
K
-
G
-----
V
L
E
T
F
S
G
T
E
-
T
N
K
I
W
P
----
Y
V
Y
A
F
L
Q
T
K
V
P
99
HHSearch
85.00
29%
-94
- C1 -
1UKZ
2
KCY_YEAST
A:
[15-202]
-
V
S
V
I
F
V
L
G
G
P
G
A
G
K
G
T
Q
C
E
K
L
V
K
D
Y
--
S
F
V
H
L
S
A
G
D
L
L
R
A
E
Q
G
R
A
G
S
Q
Y
G
E
L
I
K
N
C
I
K
E
G
Q
I
V
P
Q
E
I
---
T
L
A
L
L
R
N
A
-
I
S
D
N
--
V
K
A
-
N
K
H
K
-
F
L
I
D
G
F
P
R
K
M
D
Q
A
I
S
F
E
R
D
I
-----
V
E
S
K
F
I
L
F
F
D
C
P
E
D
I
M
L
E
R
L
L
E
R
-------------------------
G
------------------------------
K
------------------------------
T
SGR-----------------------------
S
---
D
D
-
N
I
E
S
I
K
K
R
F
N
T
F
K
E
T
S
M
---
P
V
I
E
Y
F
E
T
K
-
S
-----
K
V
V
R
V
R
C
D
R
S
V
E
D
V
Y
K
----
D
V
Q
D
A
I
R
D
S
L
-
98
HHSearch
84.70
32%
-94
- C1 -
2BWJ
3
KAD5_HUMAN
A:
[11-197]
K
C
K
I
I
F
I
I
G
G
P
G
S
G
K
G
T
Q
C
E
K
L
V
E
K
Y
--
G
F
T
H
L
S
T
G
E
L
L
R
E
E
L
A
-
S
E
S
E
R
S
K
L
I
R
D
I
M
E
R
G
D
L
V
P
S
G
I
---
V
L
E
L
L
K
E
A
-
M
V
A
S
--
L
G--
D
T
R
G
-
F
L
I
D
G
Y
P
R
E
V
K
Q
G
E
E
F
G
R
R
-----
I
G
D
P
Q
L
V
I
C
M
D
C
S
A
D
T
M
T
N
R
L
L
Q
M
-------------------------
S
------------------------------
R
------------------------------
S
SLP-----------------------------
V
---
D
D
-
T
T
K
T
I
A
K
R
L
E
A
Y
Y
R
A
S
I
---
P
V
I
A
Y
Y
E
T
K
-
T
-----
Q
L
H
K
I
N
A
E
G
T
P
E
D
V
F
L
----
Q
L
C
T
A
I
D
S
I
F
L
4
PsiBlast_PDB
84.65
31%
-76
- C1 -
4NTZ
1
KAD_STRP2
A:
[8-216]
----
L
L
I
M
G
L
P
G
A
G
K
G
T
Q
A
A
K
I
V
E
Q
F
H
--
V
A
H
I
S
T
G
D
M
F
R
A
A
M
A
-
N
Q
T
E
M
G
V
L
A
K
S
Y
I
D
K
G
E
L
V
P
D
E
V
T
N
G
I
V
K
E
R
L
S
Q
-
D
D
I
---
K
---
E
T
G
F
-
L
L
-
D
G
Y
P
R
T
I
E
Q
A
H
A
L
D
K
T
L
-
A
E
L
G
I
E
L
E
G
I
I
N
I
E
V
N
P
D
S
L
L
E
R
L
S
G
R
I
I
H
RVT
G
E
T
F
H
KVFNPPVDYKEED
Y
Y
------------------------------
Q
------------------------------
R
--------------------------------
E
---
D
D
-
K
P
E
T
V
K
R
R
L
D
V
N
I
A
Q
G
E
---
P
I
I
A
H
Y
R
A
K
-
G
-----
L
V
H
D
I
E
G
N
Q
D
I
N
D
V
F
S
----
D
I
E
K
V
L
T
N
L
K
-
20
PsiBlast_PDB
84.56
27%
-93
- C1 -
2RH5
-
KAD_AQUAE
A:
[2-198]
---
I
L
V
F
L
G
P
P
G
A
G
K
G
T
Q
A
K
R
L
A
K
E
K
G
--
F
V
H
I
S
T
G
D
I
L
R
E
A
V
Q
-
K
G
T
P
L
G
K
K
A
K
E
Y
M
E
R
G
E
L
V
P
D
D
L
---
I
I
A
L
I
E
E
V
-
F
-----
P
---
K
H
G
N
-
V
I
F
D
G
F
P
R
T
V
K
Q
A
E
A
L
D
E
M
L
E
K
K
G
-
L
K
V
D
H
V
L
L
F
E
V
P
D
E
V
V
I
E
R
L
S
G
R
-------------------------
R
INPETG
E
V
Y
H
VKYNPPPPGV
K
V
I
-------
Q
------------------------------
R
--------------------------------
E
---
D
D
-
K
P
E
V
I
K
K
R
L
E
V
Y
R
E
Q
T
A
---
P
L
I
E
Y
Y
K
K
K
-
G
-----
I
L
R
I
I
D
A
S
K
P
V
E
E
V
Y
R
----
Q
V
L
E
V
I
-----
24
PsiBlast_CBE
84.47
31%
-75
- C1 -
4NU0
2
KAD_STRP2
B:
[8-216]
----
L
L
I
M
G
L
P
G
A
G
K
G
T
Q
A
A
K
I
V
E
Q
F
H
--
V
A
H
I
S
T
G
D
M
F
R
A
A
M
A
-
N
Q
T
E
M
G
V
L
A
K
S
Y
I
D
K
G
E
L
V
P
D
E
V
TNG
I
V
K
E
R
L
S
Q
-
D
D
I
---
K
---
E
T
G
F
-
L
L
-
D
G
Y
P
R
T
I
E
Q
A
H
A
L
D
K
T
L
-
A
E
L
G
I
E
L
E
G
I
I
N
I
E
V
N
P
D
S
L
L
E
R
L
S
G
R
IIHRVTGETFHKVFNPPVDYKEEDY
Y
------------------------------
Q
------------------------------
R
--------------------------------
E
---
D
D
-
K
P
E
T
V
K
R
R
L
D
V
N
I
A
Q
G
E
---
P
I
I
A
H
Y
R
A
K
-
G
-----
L
V
H
D
I
E
G
N
Q
D
I
N
D
V
F
S
----
D
I
E
K
V
L
T
N
L
K
-
93
HHSearch
84.12
28%
-93
- C1 -
2C95
2
KAD1_HUMAN
A:
[8-195]
K
T
N
I
I
F
V
V
G
G
P
G
S
G
K
G
T
Q
C
E
K
I
V
Q
K
Y
--
G
Y
T
H
L
S
T
G
D
L
L
R
S
E
V
S
-
S
G
S
A
R
G
K
K
L
S
E
I
M
E
K
G
Q
L
V
P
L
E
T
---
V
L
D
M
L
R
D
A
-
M
V
A
K
--
V
N--
T
S
K
G
-
F
L
I
D
G
Y
P
R
E
V
Q
Q
G
E
E
F
E
R
R
I
-----
G
Q
P
T
L
L
L
Y
V
D
A
G
P
E
T
M
T
Q
R
L
L
K
R
-------------------------
G
------------------------------
E
------------------------------
T
SGR-----------------------------
V
---
D
D
-
N
E
E
T
I
K
K
R
L
E
T
Y
Y
K
A
T
E
---
P
V
I
A
F
Y
E
K
R
-
G
-----
I
V
R
K
V
N
A
E
G
S
V
D
S
V
F
S
----
Q
V
C
T
H
L
D
A
L
L
-
23
PsiBlast_CBE
84.09
31%
-79
- C1 -
4W5J
2
KAD_STRP2
B:
[8-216]
----
L
L
I
M
G
L
P
G
A
G
K
G
T
Q
A
A
K
I
V
E
Q
F
H
--
V
A
H
I
S
T
G
D
M
F
R
A
A
M
A
-
N
Q
T
E
M
G
V
L
A
K
S
Y
I
D
K
G
E
L
V
P
D
E
V
TNG
I
V
K
E
R
L
S
Q
-
D
D
I
---
K
---
E
T
G
F
-
L
L
-
D
G
Y
P
R
T
I
E
Q
A
H
A
L
D
K
T
L
-
A
E
L
G
I
E
L
E
G
I
I
N
I
E
V
N
P
D
S
L
L
E
R
L
S
G
R
IIHRVTGETFHKVFNPPVYKEEDY-
Y
------------------------------
Q
------------------------------
R
--------------------------------
E
---
D
D
-
K
P
E
T
V
K
R
R
L
D
V
N
I
A
Q
G
E
---
P
I
I
A
H
Y
R
A
K
-
G
-----
L
V
H
D
I
E
G
N
Q
D
I
N
D
V
F
S
----
D
I
E
K
V
L
T
N
L
K
-
92
HHSearch
84.03
32%
-87
* C1 *
3BE4
3
?
A:
[4-217]
K
K
H
N
L
I
L
I
G
A
P
G
S
G
K
G
T
Q
C
E
F
I
K
K
E
Y
--
G
L
A
H
L
S
T
G
D
M
L
R
E
A
I
K
-
N
G
--
I
G
L
E
A
K
S
I
I
E
S
G
N
F
V
G
D
E
I
---
V
L
G
L
V
K
E
K
-
F
D
L
---
G
V--
C
V
N
G
-
F
V
L
D
G
F
P
R
T
I
P
Q
A
E
G
L
A
K
I
L
S
E
-
I
G
D
S
L
T
S
V
I
Y
F
E
I
D
D
S
E
I
I
E
R
I
S
G
R
-------------------------
C
------------------------------
T
------------------------------
H
PASG
R
I
Y
H
VKYNPPKQPGIDDVTG
E
P
L
V
W
R
--
D
---
D
D
-
N
A
E
A
V
K
V
R
L
D
V
F
H
K
Q
T
A
---
P
L
V
K
F
Y
E
D
L
-
G
-----
I
L
K
R
V
N
A
K
L
P
P
K
E
V
T
E
----
Q
I
K
K
I
L
-----
2
PsiBlast_PDB
82.94
30%
-81
- C1 -
1Z83
5
KAD1_HUMAN
A:
[11-195]
---
I
I
F
V
V
G
G
P
G
S
G
K
G
T
Q
C
E
K
I
V
Q
K
Y
G
Y
T
--
H
L
S
T
G
D
L
L
R
S
E
V
S
-
S
G
S
A
R
G
K
K
L
S
E
I
M
E
K
G
Q
L
V
P
L
E
T
---
V
L
D
M
L
R
D
A
-
M
V
A
K
VN
T
---
S
K
G
--
F
L
I
D
G
Y
P
R
E
V
Q
Q
G
E
E
F
E
R
R
I
-
G
Q
P
T
L
L
L
Y
----
V
D
A
G
P
E
T
M
T
Q
R
L
L
K
R
G
E
T
----------------------
S
------------------------------
G
------------------------------
R
--------------------------------
V
---
D
D
-
N
E
E
T
I
K
K
R
L
E
T
Y
Y
K
A
T
E
---
P
V
I
A
F
Y
E
K
R
-
G
-----
I
V
R
K
V
N
A
E
G
S
V
D
S
V
F
S
----
Q
V
C
T
H
L
D
A
L
L
-
3
PsiBlast_PDB
82.87
30%
-81
- C1 -
2C95
2
KAD1_HUMAN
A:
[11-195]
---
I
I
F
V
V
G
G
P
G
S
G
K
G
T
Q
C
E
K
I
V
Q
K
Y
G
Y
T
--
H
L
S
T
G
D
L
L
R
S
E
V
S
-
S
G
S
A
R
G
K
K
L
S
E
I
M
E
K
G
Q
L
V
P
L
E
T
---
V
L
D
M
L
R
D
A
-
M
V
A
K
VN
T
---
S
K
G
--
F
L
I
D
G
Y
P
R
E
V
Q
Q
G
E
E
F
E
R
R
I
-
G
Q
P
T
L
L
L
Y
----
V
D
A
G
P
E
T
M
T
Q
R
L
L
K
R
G
ET----------------------
S
------------------------------
G
------------------------------
R
--------------------------------
V
---
D
D
-
N
E
E
T
I
K
K
R
L
E
T
Y
Y
K
A
T
E
---
P
V
I
A
F
Y
E
K
R
-
G
-----
I
V
R
K
V
N
A
E
G
S
V
D
S
V
F
S
----
Q
V
C
T
H
L
D
A
L
L
-
30
PsiBlast_CBE
82.35
31%
-83
- C1 -
3TLX
3
?
B:
[32-237]
----
Y
I
F
L
G
A
P
G
S
G
K
G
T
Q
S
L
N
L
K
K
--
S
H
C
Y
C
H
L
S
T
G
D
L
L
R
E
A
A
E
-
K
K
T
E
L
G
L
K
I
K
N
I
I
N
E
G
K
L
V
D
D
Q
M
---
V
L
S
L
V
D
E
K
-
L
K
T
PQ-
C
---
K
K
G
F
-
I
L
-
D
G
Y
P
R
N
V
K
Q
A
E
D
L
N
K
L
L
-
Q
K
N
Q
T
K
L
D
G
V
F
Y
F
N
V
P
D
E
V
L
V
N
R
I
S
G
R
-------------------------
L
IHKPSG
R
I
Y
H
KIFNPPKVPFRDDVTNEPLI
Q
------------------------------
R
--------------------------------
E
---
D
D
-
N
E
D
V
L
K
K
R
L
T
V
F
K
S
E
T
S
---
P
L
I
S
Y
Y
K
N
K
-
N
-----
L
--
L
I
N
L
D
A
T
--
Q
P
A
N
----
D
L
E
K
K
I
S
Q
H
I
D
14
PsiBlast_PDB
80.84
31%
-80
- C1 -
3TLX
3
?
A:
[32-237]
----
Y
I
F
L
G
A
P
G
S
G
K
G
T
Q
S
L
N
L
K
K
--
S
H
C
Y
C
H
L
S
T
G
D
L
L
R
E
A
A
E
-
K
K
T
E
L
G
L
K
I
K
N
I
I
N
E
G
K
L
V
D
D
Q
M
---
V
L
S
L
V
D
E
K
-
L
K
T
PQ-
C
---
K
K
G
F
-
I
L
-
D
G
Y
P
R
N
V
K
Q
A
E
D
L
N
K
L
L
-
Q
K
N
Q
T
K
L
D
G
V
F
Y
F
N
V
P
D
E
V
L
V
N
R
I
S
G
R
-------------------------
L
IHKPSG
R
I
Y
H
KIFNPPKVPFRDDVTN
E
P
L
I
Q
------------------------------
R
--------------------------------
E
---
D
D
-
N
E
D
V
L
K
K
R
L
T
V
F
K
S
E
T
S
---
P
L
I
S
Y
Y
K
N
K
-
N
-----
L
--
L
I
N
L
D
A
T
--
Q
P
A
N
----
D
L
E
K
K
I
S
Q
H
I
D
106
HHSearch
78.40
31%
-74
- C1 -
2CDN
3
KAD_MYCTU
A:
[20-200]
-
H
M
R
V
L
L
L
G
P
P
G
A
G
K
G
T
Q
A
V
K
L
A
E
K
L
--
G
I
P
Q
I
S
T
G
E
L
F
R
R
N
I
E
-
E
G
T
K
L
G
V
E
A
K
R
Y
L
D
A
G
D
L
V
P
S
D
L
---
T
N
E
L
V
D
D
R
-
L
N
N
P--
D
---
A
A
N
G
-
F
I
L
D
G
Y
P
R
S
V
E
Q
A
K
A
L
H
E
M
L
E
R
-
R
G
T
D
I
D
A
V
L
E
F
R
V
S
E
E
V
L
L
E
R
L
K
G
R
-------------------------
G
------------------------------
R
---------------------------------------------------------------
A
---
D
D
-
T
D
D
V
I
L
N
R
M
K
V
Y
R
D
E
T
A
---
P
L
L
E
Y
Y
R
D
Q
--------
L
K
T
V
D
A
V
G
T
M
D
E
V
F
A
----
R
A
L
R
A
L
G
K
---