@TOME V2.3
(Nov 2016)

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3D Common Core:

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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : jhp_0568: (2015-12-16 )
MTFEPYPFERLRALFKEITPKKKGLDLGIGEPRFETPKFIQDALKSHTHSLNIYPKSAFEESLREAQRGFFKRRFKIELKENELVSTLGSREVLFNFPSFVLFDYPNPTIAYPNPFYQIYEGSAQFARAKSLLMPLVKENDFTPSLNEKELQEVDLVILNSPNNPTGRTLSLEELIAWVKLALKHDFILINDECYSEIYENTPPSSLLEACMLADNGAFKNVLVIHSLSKRSSAPGLRSGFIAGDSSLLEKYKAFRTYLGYTSANAIQKASEVAWLDDRHAEFFRNIYANNLKLARKIFKETLIYPYSFYAYLPVKDGENFAKTLYQNEGITTLPALYLGRNHIGADYVRLALVYDTSLLEKPLEIIEAYRENYA

Atome Classification :

(20 SA) .........10.......-.-20.--..---...---..30........40.-..----.-....--50..-......--60........70....-.--...-80.-.-.......90........100--.-...--...110.......120.......130.--......---------140.---.--.-..---....150--...----.---....160.......170.......180.......190.....-.-.---200.-......210.......220..-.....230.......240...-....250.......260........270......--------.----.--------.280-.........290.......300-----..-------.---..--------.-----..------310.---..-..--------------..---320.........330.......340----.----......350.......360...-....370...
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MTFEPYPFERLRALFKEI-T-PKK--KG---LDL---GIGEPRFETPKFIQD-AL----K-SHTH--SLNI-YPKSAF--EESLREAQRGFFKRRF-K--IEL-K-E-N-ELVSTLGSREVLFNFPSFVL--F-DYP--NPTIAYPNPFYQIYEGSAQFARAKSLL--MPLVKE---------N--D---F--T-PS---LNEKEL---QEV----D---LVILNSPNNPTGRTLSLEELIAWVKLALKHDFILINDECYSE-I-Y---ENTP-PSSLLEACMLADNGAFKNVLV-IHSLSKRSSAPGLRSGFIAGD-SSLLEKYKAFRTYLG-YTSANAIQKA--SEVAWL--------D----D--------RH---AEFFRNIYANNLKLARKIFKE------TL-------I---YP--------Y-----SF------YAYL---PV-KD--------------GE---N--FAKTLYQNEGITTLPALYLGRN----H----IGADYVRLALVYDTSLLEKPLE-IIEAYRENYA
1 PsiBlast_PDB 99.8491%-104 - C1 -3EZS ? A:[3-374] -TFEPYPFERLRALLKEI-T-PKK--RG---LDL---GIGEPQFETPKFIQD-AL----K-NHTH--SLNI-YPKSAF--EESLRAAQRGFFKRRF-K--IEL-K-E-N-ELISTLGSREVLFNFPSFVL--F-DYQ--NPTIAYPNPFYQIYEGAAKFIKAKSLL--MPLTKE---------N--D---F--T-PS---LNEKEL---QEV----D---LVILNSPNNPTGRTLSLEELISWVKLALKHDFILINDECYSE-I-Y---ENTP-PPSLLEACMLAGNEAFKNVLV-IHSLSKRSSAPGLRSGFIAGD-SRLLEKYKAFRAYLG-YTSANAIQKA--SEAAWL--------D----D--------RH---AEFFRNIYANNLKLARKIFKN------TL-------I---YP--------Y-----SF------YVYL---PV-QN--------------GE---N--FAKTLYQNEGIITLPALYLGRN----R----IGADYVRLALVYDTPLLEKPLE-IIETYREN--
25 HHSearch 96.2689%-100 - C1 -3EZS ? A:[2-374] MTFEPYPFERLRALLKEI-T-PKK--RG---LDL---GIGEPQFETPKFIQD-AL----K-NHTH--SLNI-YPKSAF--EESLRAAQRGFFKRRF-K--IEL-K-E-N-ELISTLGSREVLFNFPSFVLF-DYQNP--T--IAYPNPFYQIYEGAAKFIKAKSLL--MPLTKE---------N--D---F--TPSL---NEKEL----QEV----D---LVILNSPNNPTGRTLSLEELISWVKLALKHDFILINDECYSE-I-Y---ENTP-PPSLLEACMLAGNEAFKNVLV-IHSLSKRSSAPGLRSGFIAGD-SRLLEKYKAFRAYLG-YTSANAIQKA--SEAAWL--------D----D--------RH---AEFFRNIYANNLKLARKIFKNT-----LI-------Y---P---------Y-----SF------YVYL---PV-QN--------------GE---N--FAKTLYQNEGIITLPALYLGRN----R----IGADYVRLALVYDTPLLEKPLE-IIETYREN--
2 PsiBlast_PDB 71.0737% -75 - C1 -3JTX ? A:[9-396] --LKPYPFARLHEAMQGI-S-APEGMEA---VPL---HIGEPKHPTPKVITD-AL----T-ASLH--ELEK-YPLTAG--LPELRQACANWLKRRY-DGLTVD-A-D-N-EILPVLGSREALFSFVQTVLNP---GI--KPAIVSPNPFYQIYEGATLLGGGEIHFANCPAPSF---------N--P---D--W-RS---ISEEVW---KRT----K---LVFVCSPNNPSGSVLDLDGWKEVFDLQDKYGFIIASDECYSE-I-YFD-GNKP-LGCLQAAAQLGR--SRQKLLM-FTSLSKRSNVPGLRSGFVAGD-AELLKNFLLYRTYHG-SAMSIPVQRA--SIAAWD--------D----E--------QH---VIDNRRLYQEKFERVIPILQQ------VFDVK----L---PD--------A-----SF------YIWL---KV-PD--------------GD---DLAFARNLWQKAAIQVLPGRFLARDTEQGN----PGEGYVRIALVADVATCVKAAEDIVSLYR----
29 HHSearch 70.0638% -85 - C1 -3JTX ? A:[27-395] -------------------P-EGM--EA---VPL---HIGEPKHPTPKVITD-AL----T-ASLH--ELEK-YPLTAG--LPELRQACANWLKRRYDG--LTV-D-A-DNEILPVLGSREALFSFVQTVL--N-P--GIKPAIVSPNPFYQIYEGATLLGGGEIHF--ANCPA----------P--S---FNPDWRS---ISEEVW---KRT----K---LVFVCSPNNPSGSVLDLDGWKEVFDLQDKYGFIIASDECYSE-I-Y---FDGNKPLGCLQAAAQ-LGRSRQKLLM-FTSLSKRSNVPGLRSGFVAGD-AELLKNFLLYRTYHG-SAMSIPVQRA--SIAAWD--------D----E--------QH---VIDNRRLYQEKFERVIPILQQVFD---VK-------L---PD--------A-----SF------YIWL---KV-PDGD------------DL---A--FARNLWQKAAIQVLPGRFLARD----TEQGNPGEGYVRIALVADVATCVKAAE-DIVSLYR---
6 PsiBlast_PDB 62.9526% -83 - C1 -2X5D ? A:[29-393] ----------------KM-A-ARR--RGEDIIDL---SMGNPDGPTPPHIVE-KLCTVA---------------TSRG--IPRLRRAISHWYRDRY-D--VQI-DPE-S-EAIVTIGSKEGLAHL-MLAT--L-DHG--D-TILVPNPSYPIHIYGAVIAGAQVRS--VPLVPG---------I--D---F--F-NE---L-ERAI---RESIPKPR---MMILGFPSNPTAQCVELDFFERVVALAKQYDVMVVHDLAYAD-IVY---DGWK-APSIMQV-----PGAKDIAVE-FFTLS-SYNMAGWRIGFMVGN-PELVSALARIKSYHD-YGTFTPLQVA--AIAALE--------G----DQQCVRDIARQ---YQQRRDVLVKGLREAGWMVEN------PK-------A---SM--------Y-----VWAKIPEPYAHL-------G--------------SL---E--FAKKLLQDAKVSVSPGIGFG------D----YGDDHVRFALIENRDRLRQAVR-GIKAMFRADG
35 HHSearch 62.3420% -63 - C1 -3H14 ? A:[11-382] --VDPFIVMDVMEAARRAEE-AGR--RI---IHM---EVGQPGTGAPRGAVE-AL----A-KSLE------------G--LPALRQRIARLYGEWY-G--VDL-D-P-G-RVVITPGSSGGFLLAFTALF--D-SGD--R--VGIGAPGYPSYRQILRALGLVPVD--LPTAPE---------N--R---L--Q-PV---PADFAG---LDL----A---GLMVASPANPTGTMLDHAAMGALIEAAQAQGASFISDEIYHG-I-E---YEAK-AVTA--------LELTDECYV-INSFSKYFSMTGWRVGWMVVP-EDQVRVVERIAQNMF-ICAPHASQVA--ALAALD--------C----D--------AE---LQANLDVYKANRKLMLERLPKAGFTR-IA-------P---PD--------G-----AF------YVYA---DV-SDLTDD----------SR---A--FAAEILEKAGVAVTPGLDFDPE----R-----GAGTLRFSYARATADIEEGLD-RLEAFMQAR-
34 HHSearch 62.2625% -79 - C1 -2X5D ? A:[21-398] ------VFNITAELKMAA-RRRGE--DI---IDL---SMGNPDGPTPPHIVE-KL----C-TVA----------TSRG--IPRLRRAISHWYRDRY-D--VQI-D-P-ESEAIVTIGSKEGLAHLMLATL--D-HGD--T--ILVPNPSYPIHIYGAVIAGAQVRS--VPLVPG---------I--D---F--F-NE---LERAIRESIPKP----R---MMILGFPSNPTAQCVELDFFERVVALAKQYDVMVVHDLAYAD-I-V---YDGWKAPSIMQV-----PGAKDIAVE-FFTLS-SYNMAGWRIGFMVGN-PELVSALARIKSYHD-YGTFTPLQVA--AIAALE--------GD---Q--------QC---VRDIARQYQQRRDVLVKGLREAGWM--VE-------N---PK--------A-----SM------YVWA---KI-PEPYAHLG--------SL---E--FAKKLLQDAKVSVSPGIGFGDY----------GDDHVRFALIENRDRLRQAVR-GIKAMFRADG
3 PsiBlast_PDB 62.1226% -71 - C1 -1GDE ? A:[15-380] ----------IRKLFDIA-A-GMK--DV---ISL---GIGEPDFDTPQHIKEYAK----E-ALDK--GLTH-YGPNIG--LLELREAIAEKLKKQN-G--IEA-DPK-T-EIMVLLGANQAFLMGLSAFL--K-D----GEEVLIPTPAFVSYAPAVILAGGKPVE--VPTYEE---------D--E---F--R-LN---VDELKK---YVT----DKTRALIINSPCNPTGAVLTKKDLEEIADFVVEHDLIVISDEVYEHFI-Y---DDAR-HYSIASL-----DGMFERTIT-VNGFSKTFAMTGWRLGFVAAP-SWIIERMVKFQMYNA-TCPVTFIQYA--AAKALK--------D----E--------RSWKAVEEMRKEYDRRRKLVWKRLNEMGLP--TV-------K---PK--------G-----AF------YIFP---RI-RDTGLT----------SK---K--FSELMLKEARVAVVPGSAFGKA----------GEGYVRISYATAYEKLEEAMD-RMERVLKERK
11 PsiBlast_PDB 61.7923% -81 - C1 -1J32 ? A:[26-383] ----------------------KA--EG---IDVCSFSAGEPDFNTPKHIVE-AA----K-AALE--QGKTRYGPAAG--EPRLREAIAQKLQRDN-G--LCY-G-A-D-NILVTNGGKQSIFNL--MLA--M-IEP--GDEVIIPAPFWVSYPEMVKLAEGTPVI--LPTTVE---------T--Q---F--K-VSPEQIRQAIT---PKT----K---LLVFNTPSNPTGMVYTPDEVRAIAQVAVEAGLWVLSDEIYEK-ILY---DDAQ-HLSI----GAASPEAYERSVV-CSGFAKTYAMTGWRVGFLAGP-VPLV---KAATKIQG-HSTSNVCTFAQYGAIAAY--------E----N--------SQ----DCVQEMLAAFAERRRYMLDA------LN-------A---MPGLECPKPDG-----AF------YMFP---SIAKT--------------GRSSLD--FCSELLDQHQVATVPGAAFGAD------------DCIRLSYATDLDTIKRGME-RLEKFLHGIL
4 PsiBlast_PDB 59.9726% -69 - C1 -1GD9 ? A:[15-380] ----------IRKLFDIA-A-GMK--DV---ISL---GIGEPDFDTPQHIKEYAK----E-ALDK--GLTH-YGPNIG--LLELREAIAEKLKKQN-G--IEA-DPK-T-EIMVLLGANQAFLMGLSAFL--K-D----GEEVLIPTPAFVSYAPAVILAGGKPVE--VPTYEE---------D--E---F--R-LN---VDELKK---YVT----DKTRALIINSPCNPTGAVLTKKDLEEIADFVVEHDLIVISDEVYEHFI-Y---DDAR-HYSIASL-----DGMFERTIT-VNGFSKTFAMTGWRLGFVAAP-SWIIERMVKFQMYNA-TCPVTFIQYA--AAKALK--------D----E--------RSWKAVEEMRKEYDRRRKLVWKRLNEMGLP--TV-------K---PK--------G-----AF------YIFP---RI-RDTGLT----------SK---K--FSELMLKEARVAVVPGSAFGKA----------GEGYVRISYATAYEKLEEAMD-RMERVLKERK
39 HHSearch 59.1521% -72 - C1 -3E2Y KAT3_MOUSE A:[14-409] ------------VEFTKL-A-ADP--SV---VNL---GQGFPDISPPSYVKE-EL----S-KAAFIDNMNQ-YTRGFG--HPALVKALSCLYGKIY-Q--RQI-DPN-E-EILVAVGAYGSLFNSIQGLV--D-PGD--E--VIIMVPFYDCYEPMVRMAGAVPVF--IPLRSKPTDGMKWTSS--DWT-F--DPRE---LESKFS---SKT----K---AIILNTPHNPLGKVYTRQELQVIADLCVKHDTLCISDEVYEW-L-V---YTGHTHVKIATL-----PGMWERTIT-IGSAGKTFSVTGWKLGWSIGP-AHLIKHLQTVQQNSF-YTCATPLQAA--LAEAFWIDIKRMDDP----E--------CY---FNSLPKELEVKRDRMVRLLNSVGLK--PI-------V---PD--------G-----GY------FIIA---DV-SSLGADLSDMNSDEPYDY---K--FVKWMTKHKKLTAIPVSAFCDS----KSKP-HFEKLVRFCFIKKDSTLDAAEE-IFRAWN----
7 PsiBlast_PDB 57.2826% -75 - C1 -2O1B ? A:[50-391] -------------------------------INM---AVGIPDGPTPQGIID-HF----Q-KALT--IPEN-QKYGAFHGKEAFKQAIVDFYQRQY-N--VTLDK-E-D-EVCILYGTKNGLVAVPTCVI-----NP--GDYVLLPDPGYTDYLAGVLLADGKPVP--LNLEPP---------H------Y--L-PD---WSKVDS---QII----DKTKLIYLTYPNNPTGSTATKEVFDEAIAKFKGTDTKIVHDFAYGA-F-G---FDAK-NPSILAS----ENG--KDVAIEIYSLSKGYNMSGFRVGFAVGN-KDMIQALKKYQTHTN-AGMFGALQDA--AIYAL-----------------------NH---YDDFLEEQSNVFKTRRDRFEA------ML-------AKADLP--------FVHAKGGI------YVWLETPPG-YD--------------SE---Q--FEQFLVQEKSILVAPGKPFGEN----------GNRYVRISLALDDQKLDEAAI-RLTELAYLYE
26 HHSearch 57.0226% -68 - C1 -1GD9 ? A:[22-387] -----------------A-A-GMK--DV---ISL---GIGEPDFDTPQHIKE-YA----K-EALDK-GLTH-YGPNIG--LLELREAIAEKLKKQN-G--IEA-D-PKT-EIMVLLGANQAFLMGLSAFL--K-DGE--E--VLIPTPAFVSYAPAVILAGGKPVE--VPTYEE---------D--EFR-L--NVDE---LKKYVT---DKT----R---ALIINSPCNPTGAVLTKKDLEEIADFVVEHDLIVISDEVYEH-F-I---YDDARHYSIASL-----DGMFERTIT-VNGFSKTFAMTGWRLGFVAAP-SWIIERMVKFQMYNA-TCPVTFIQYA--AAKALK--------D----ERSW-----KA---VEEMRKEYDRRRKLVWKRLNEMGLP--TV-------K---PK--------G-----AF------YIFP---RI-RDTGLT----------SK---K--FSELMLKEARVAVVPGSAFGKA----------GEGYVRISYATAYEKLEEAMD-RMERVLKERK
12 PsiBlast_PDB 55.9823% -65 - C1 -1BKG AAT_THET8 A:[27-376] ----------------------RR--QG---VDLVALTAGEPDFDTPEHVKE-AA----RRALAQ--GKTK-YAPPAG--IPELREALAEKFRREN-G--LSV-T-P-E-ETIVTVGGKQALFNLFQAIL-----DP--GDEVIVLSPYWVSYPEMVRFAGGVVVE--VETLPE---------E--G---F--V-PDPERVRRAIT---PRT----K---ALVVNSPNNPTGAVYPKEVLEALARLAVEHDFYLVSDEIYEH-L-LYEGEHFS-PGRVAPEHTLTVNGAAKAFAM-T----------GWRIGYACGP-KEVIKAMASVSSQST-TSPDTIAQWA--TLEALT--------N----Q--------EA---SRAFVEMAREAYRRRRDLLLE------GLTALGLKAV---RP--------SG----AF------YVLMDTSPI-AP--------------DE---V--RAAERLLEAGVAVVP----GTD----F----AAFGHVRLSYATSEENLRKALE-RFARVL----
32 HHSearch 54.9722% -66 - C1 -1B5P AAT_THET8 A:[15-382] ------ATVAVNAKALELRR-QGV--DL---VAL---TAGEPDFDTPEHVKE-AA----R-RALAQ-GKTK-YAPPAG--IPELREALAEKFRREN-G--LSV-T-P-E-ETIVTVGGSQALFNLFQAIL--D-PGD--E--VIVLSPYWVSYPEMVRFAGGVVVE--VETLPE---------E--G---FVPDPER---VRRAIT---PRT----K---ALVVNSPNNPTGAVYPKEVLEALARLAVEHDFYLVSDEIYEH-L-L---YEGE-HFSPG-------RVAPEHTLT-VNGAAKAFAMTGWRIGYACGP-KEVIKAMASVSRQST-TSPDTIAQWA--TLEALT--------NQEASR--------AF---VEMAREAYRRRRDLLLEGLTALGLK--AV-------R---PS--------G-----AF------YVLM---DT-SPIAPD----------EV---R--AAER-LLEAGVAVVPGTDFAA------------FGHVRLSYATSEENLRKALE-RFARVL----
41 HHSearch 54.9515% -68 - C1 -1C7N ? A:[27-393] -----------------P-E-VGN--EV---VPL---SVADMEFKNPPELIE-GL----K-KYLDE-TVLG-YTG--P--TEEYKKTVKKWMKDRH-Q--WDI-Q-T-D-WIINTAGVVPAVFNAVREFT--K-PGD--G--VIIITPVYYPFFMAIKNQERKIIE--CELLEK---------D--GYYTI--DFQK---LEKLSKD--KNN----K---ALLFCSPHNPVGRVWKKDELQKIKDIVLKSDLMLWSDEIHFD-L-I---MPGYEHTVFQSID----EQLADKTIT-FTAPSKTFNIAGMGMSNIIIKNPDIRERFTKSRDATSGMPFTTLGYKA--CEICYK--------EC---G--------KW---LDGCIKVIDKNQRIVKDFFEVNHPEIKAP-------L---IE--------G-----TY------LQWI---DF-RALKMD----------HK---A--MEEFMIHKAQIFFDEGYIFGDG----------GIGFERINLAAPSSVIQESLE-RLNKALKDLK
27 HHSearch 54.8921% -69 * C1 *1O4S AAT_THEMA A:[27-388] --------MELDAKAKALIK-KGE--DV---INL---TAGEPDFPTPEPVVE-EA----V-RFLQK-GEVK-YTDPRG--IYELREGIAKRIGERY-K--KDI-S-P-D-QVVVTNGAKQALFNAFMALL--D-PGD--E--VIVFSPVWVSYIPQIILAGGTVNV--VETFMS---------KNFQ---P--SLEE---VEGLLV---GKT----K---AVLINSPNNPTGVVYRREFLEGLVRLAKKRNFYIISDEVYDS-L-V---YTDE-FTSILDV-----SEGFDRIVY-INGFSKSHSMTGWRVGYLISS-EKVATAVSKIQSHTT-SCINTVAQYA--ALKALE--------V----D-------------NSYMVQTFKERKNFVVERLKKMGVK--FV-------E---PE--------G-----AF------YLFF---KV-RGD-------------DV---K--FCERLLEEKKVALVPGSAFLK------------PGFVRLSFATSIERLTEALD-RIEDFLNS--
28 HHSearch 54.5921% -71 - C1 -1J32 ? A:[28-387] ---------------------EGI--DV---CSF---SAGEPDFNTPKHIVE-AA----K-AALEQ-GKTR-YGPAAG--EPRLREAIAQKLQRDN-G--LCY-G-A-D-NILVTNGGKQSIFNLMLAMI--E-PGD--E--VIIPAPFWVSYPEMVKLAEGTPVI--LPTTVE---------TQFK---V--SPEQ---IRQAIT---PKT----K---LLVFNTPSNPTGMVYTPDEVRAIAQVAVEAGLWVLSDEIYEK-I-L---YDDAQHLSIGAAS----PEAYERSVV-CSGFAKTYAMTGWRVGFLAGP-VPLVKAATKIQGHST-SNVCTFAQYG--AIAAYE--------NS---Q--------DC---VQEMLAAFAERRRYMLDALNAMPGLE-CP-------K---PD--------G-----AF------YMFP---SI-AKTGRS----------SL---D--FCSELLDQHQVATVPGAAFGA------------DDCIRLSYATDLDTIKRGME-RLEKFLHGIL
18 PsiBlast_PDB 53.6423% -66 - C1 -1BJW AAT_THET8 A:[27-376] ----------------------RR--QG---VDLVALTAGEPDFDTPEHVKE-AA----RRALAQ--GKTK-YAPPAG--IPELREALAEKFRREN-G--LSV-T-P-E-ETIVTVGGKQALFNLFQAIL-----DP--GDEVIVLSPYWVSYPEMVRFAGGVVVE--VETLPE---------E--G---F--V-PDPERVRRAIT---PRT----K---ALVVNSPNNPTGAVYPKEVLEALARLAVEHDFYLVSDEIYEH-L-LYEGEHFS-PGRVAPEHTLTVNGAAKAFAM-T----------GWRIGYACGP-KEVIKAMASVSSQST-TSPDTIAQWA--TLEALT--------N----Q--------EA---SRAFVEMAREAYRRRRDLLLE------GLTALGLKAV---RP--------SG----AF------YVLMDTSPI-AP--------------DE---V--RAAERLLEAGVAVVP----GTD----F----AAFGHVRLSYATSEENLRKALE-RFARVL----
31 HHSearch 53.6221% -74 - C1 -2DOU ? A:[10-375] -------FLVVDEAKRKARE-RGV--GL---IDL---SIGSTDLPPPEAPLK-AL----A-EALNDPTTYG-YCLKSC--TLPFLEEAARWYEGRY-G--VGL-D-P-RREALALIGSQEGLAHLLLALT--E-PED--L--LLLPEVAYPSYFGAARVASLRTFL--IPLRED---------G--L---A--DLKA---VPEGVW---REA----K---VLLLNYPNNPTGAVADWGYFEEALGLARKHGLWLIHDNPYVD-Q-V---YEGE-APSPLAL-----PGAKERVVE-LFSLSKSYNLAGFRLGFALGS-EEALARLERVKGVID-FNQYAGVLRM--GVEALK--------TP---K--------EV---VRGYARVYRERALGMAEALKGVLS---LL-------P---PR--------A-----TM------YLWG---RL-PEGVD-----------DL---E--FGLR-LVERGVALAPGRGFGPG----------GKGFVRIALVRPLEELLEAAK-RIREAL----