@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0646: (2015-12-17 )
MQEIENLHQSVLLQEVLQAFTPLEEGILIDCTLGLGGHSKAILSQKPHLKLIGIDKDKFAQEIAKERLKEFEGRYNLLSGGFAKRFKEALEIHGERIKGVLVDLGVSSLQLDDDNRGFNFRSHALDMRMDLESELNAQKVINSYPVVALEKIFRDYGEIKEYKKIAHKIAERRAKKPFKDAKDLSEFLSSLSKNKKIHPATLVFQAVRIEVNSELEELKEFLQCARNLKEAILCVISFHSLEDALVKNAFKDYAKNCICDPSSFKCACSNNHALGAILTKKPITPSPEEIKNNRRSRSAKMRVFQFKP
Atome Classification :
(20 SA)
--.........10-........20......---..30........40...----.-.--.-..50.....---------...-60.....----...70-..------....-------------------...80..--......---90...-.-.....100-.......110.......120.-..-..-.-..130......-.140.......150.......--.160-.-.......170.......180.......--.190.--..----.....200.......210...-....220....--------.--.--.230.......240.......250.......260.......270....--...280.......-290.......300......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--M
Q
E
I
E
N
L
H
Q
S
V
-
L
L
Q
E
V
L
Q
A
FTPLEE
G
I
---
L
I
D
C
T
LGLGGH
S
K
A
I
LS----Q-K--P-
H
L
K
L
I
GI
D
K
---------
D
K
F
-
A
Q
E
I
A
K
E
----
R
L
K
E
--
F
E------GRYN-------------------LLSG
G
F
A
--
K
R
F
K
E
A
---
L
-
E
I
H
-
G
-
E
R
I
K
G
V
L
V
-DLGV
S
S
L
Q
LDDDNRGFNF-RS-H
A
-
L
D
-
M
-
R
MD
L
E
SEL
N
A
Q
-
K
V
I
N
SY
P
V
V
A
L
E
-
K
I
F
R
D
Y
G
E
--
I
K
-
E
-
Y
-
K
K
I
A
H
K
I
A
E
R
R
AKKPF
K
D
-
A
K
D
L
S
E
F
L
--
S
S
-
L
S--KN----KKI
H
P
A
T
L
V
F
Q
A
V
R
I
E
VN
S
E
L
-
E
E
L
K
E
F
L
Q
C
A
R
--------
N
--
L
--
K
E
A
I
L
C
V
I
S
F
H
S
L
E
D
A
L
V
K
N
A
F
K
D
Y
A
K
NCICDPSS
F
K
C
ACSNNH
A
L
G
A
--
I
L
TKKPITP
S
P
E
E
-
I
K
N
N
R
RSRSAK
M
R
V
F
QFKP
4
PsiBlast_PDB
93.14
36%
-87
- C1 -
3TKA
8
RSMH_ECOLI
A:
[42-341]
----------
T
T
V
-
L
L
D
E
A
V
N
G
L
N
I
R
P
D
G
I
---
Y
I
D
G
T
F
G
R
G
G
H
S
R
L
I
L
S
----
Q
L
G
--
E
-
E
G
R
L
L
A
I
D
R
---------
D
P
Q
-
A
I
A
V
A
K
T
IDDP
R
F
S
I
--
I
H
------
G
P
F
S
-------------------
A
L
G
E
Y
V
A
--
E
R
---------
D
L
I
-
G
--
K
I
D
G
I
L
L
-
D
L
G
V
S
S
P
Q
L
D
D
A
E
R
G
F
S
F
M
R
D
-
G
P
-
L
D
-
M
-
R
M
D
P
T
R
G
Q
S
A
A
-
E
W
L
Q
T
A
E
E
A
D
I
A
-
W
V
L
K
T
Y
G
E
--
E
R
-
F
-
A
-
K
R
I
A
R
A
I
V
E
R
N
R
E
Q
P
M
T
R
-
T
K
E
L
A
E
V
V
--
A
A
-
A
T
PV
K
--------
H
P
A
T
R
T
F
Q
A
V
R
I
W
V
N
S
E
L
-
E
E
I
E
Q
A
L
K
S
S
L
--------
N
--
V
LA
P
G
G
R
L
S
I
I
S
F
H
S
L
E
D
R
I
V
K
R
F
M
R
E
N
S
R
G
--------------------RQ
L
R
A
L
G
K
L
M
P
G
E
E
E
-
V
A
E
N
P
R
A
R
S
S
V
L
R
I
A
E
R
T
N
22
HHSearch
92.58
35%
-74
- C1 -
3TKA
8
RSMH_ECOLI
A:
[42-345]
----------
T
T
V
-
L
L
D
E
A
V
N
G
L
N
I
R
P
D
G
I
---
Y
I
D
G
T
F
G
R
G
G
H
S
R
L
I
L
S
----
Q
-
L
G-
E
-
E
G
R
L
L
A
I
D
R
---------
D
P
Q
-
A
I
A
V
A
K
T
----
I
D
D
-----------
P
R
F
S
-------------------
I
I
H
G
P
F
S
--
A
L
G
E
Y
V
---
A
-
E
R
D
L
I
-
G
K
I
D
G
I
L
L
-
D
L
G
V
S
S
P
Q
L
D
D
A
E
R
G
F
S
F
-
M
R
D
G
P
-
L
D
-
M
-
R
M
D
P
T
R
G
Q
S
A
A
-
E
W
L
Q
T
A
E
E
A
D
I
A
-
W
V
L
K
T
Y
G
E
--
E
R
-
F
-
A
-
K
R
I
A
R
A
I
V
E
R
N
R
E
Q
P
M
T
R
-
T
K
E
L
A
E
V
V
--
A
A
A
T
P
--
V
K
-------
H
P
A
T
R
T
F
Q
A
V
R
I
W
V
N
S
E
L
-
E
E
I
E
Q
A
L
K
S
S
L
--------
N
V
L
A
--
P
G
G
R
L
S
I
I
S
F
H
S
L
E
D
R
I
V
K
R
F
M
R
E
N
S
R
G
------------------
R
Q
--
L
R
A
L
G
K
L
M
P
G
E
E
E
-
V
A
E
N
P
R
A
R
S
S
V
L
R
I
A
E
R
T
N
23
HHSearch
92.13
45%
-79
* C1 *
1M6Y
2
RSMH_THEMA
A:
[4-296]
---
R
K
Y
S
Q
R
H
I
P
V
-
M
V
R
E
V
I
E
F
L
K
P
E
D
E
K
I
---
I
L
D
C
T
V
G
E
G
G
H
S
R
A
I
L
E
----
H
-
C
--
P
-
G
C
R
I
I
G
I
D
V
---------
D
S
E
-
V
L
R
I
A
E
E
----
K
L
K
E
--
F
S
------
D
R
V
S
-------------------
L
F
K
V
S
Y
R
--
E
A
D
F
L
L
---
K
-
T
L
G
-
I
-
E
K
V
D
G
I
L
M
-
D
L
G
V
S
T
Y
Q
L
K
G
E
N
R
G
F
T
F
-
E
R
E
E
P
-
L
D
-
M
-
R
M
D
L
E
S
E
V
T
A
Q
-
K
V
L
N
E
L
P
E
E
E
L
A
-
R
I
I
F
E
Y
G
E
--
E
K
R
F
-
A
-
R
R
I
A
R
K
I
V
E
N
R
---
P
L
N
T
-
T
L
D
L
V
K
A
V
--
R
E
A
L
P
--
S
Y
E
I
R
R
R
K
R
H
F
A
T
K
T
F
Q
A
I
R
I
Y
V
N
R
E
L
-
E
N
L
K
E
F
L
K
K
A
E
--------
D
LL
N
--
P
G
G
R
I
V
V
I
S
F
H
S
L
E
D
R
I
V
K
E
T
F
R
N
S
K
-------------------
K
L
R
--
I
L
T
E
K
P
V
R
P
S
E
E
E
-
I
R
E
N
P
R
A
R
S
G
R
L
R
A
A
E
R
I
-
2
PsiBlast_PDB
90.90
43%
-76
- C1 -
1N2X
2
RSMH_THEMA
A:
[10-291]
---------
H
I
P
V
-
M
V
R
E
V
I
E
F
L
K
P
E
D
E
K
I
---
I
L
D
C
T
V
G
E
G
G
H
S
R
A
I
L
E
----
H
-
C
--
P
-
G
C
R
I
I
G
I
D
V
---------
D
S
E
-
V
L
R
I
A
E
E
----
K
L
K
E
--
F
S
------
D
R
V
S
-------------------
L
----
F
K
--
V
S
Y
R
E
A
D
F
L
L
-
K
T
L
-
G
I
E
K
V
D
G
I
L
M
-
D
L
G
V
S
T
Y
Q
L
K
G
E
N
R
G
F
T
F
E
R
E
-
E
P
-
L
D
-
M
-
R
M
D
L
E
S
E
V
T
A
Q
-
K
V
L
N
E
L
P
E
E
E
L
A
-
R
I
I
F
E
Y
G
E
--
E
K
-
R
-
F
A
R
R
I
A
R
K
I
V
E
N
R
P
L
N
T
T
L
D
L
V
K
A
V
R
E
A
L
--
P
S
-
Y
E
I
-
R
R
----
R
K
R
H
F
A
T
K
T
F
Q
A
I
R
I
Y
V
N
R
E
L
-
E
N
L
K
E
F
L
K
K
A
E
--------
D
--
L
LN
P
G
G
R
I
V
V
I
S
F
H
S
L
E
D
R
I
V
K
E
T
F
R
N
S
K
K
L
-------------------
R
--
I
L
T
E
K
P
V
R
P
S
E
E
E
-
I
R
E
N
P
R
A
R
S
G
R
L
R
A
A
E
R
I
-
1
PsiBlast_PDB
90.12
43%
-78
- C1 -
1M6Y
2
RSMH_THEMA
A:
[10-291]
---------
H
I
P
V
-
M
V
R
E
V
I
E
F
L
K
P
E
D
E
K
I
---
I
L
D
C
T
V
G
E
G
G
H
S
R
A
I
L
E
----
H
-
C
--
P
-
G
C
R
I
I
G
I
D
V
---------
D
S
E
-
V
L
R
I
A
E
E
----
K
L
K
E
--
F
S
------
D
R
V
S
-------------------
L
----
F
K
--
V
S
Y
R
E
A
D
F
L
L
-
K
T
L
-
G
I
E
K
V
D
G
I
L
M
-
D
L
G
V
S
T
Y
Q
L
K
G
E
N
R
G
F
T
F
E
R
E
-
E
P
-
L
D
-
M
-
R
M
D
L
E
S
E
V
T
A
Q
-
K
V
L
N
E
L
P
E
E
E
L
A
-
R
I
I
F
E
Y
G
E
--
E
K
-
R
-
F
A
R
R
I
A
R
K
I
V
E
N
R
P
L
N
T
T
L
D
L
V
K
A
V
R
E
A
L
--
P
S
-
Y
E
I
-
R
R
----
R
K
R
H
F
A
T
K
T
F
Q
A
I
R
I
Y
V
N
R
E
L
-
E
N
L
K
E
F
L
K
K
A
E
--------
D
--
L
LN
P
G
G
R
I
V
V
I
S
F
H
S
L
E
D
R
I
V
K
E
T
F
R
N
S
K
K
L
-------------------
R
--
I
L
T
E
K
P
V
R
P
S
E
E
E
-
I
R
E
N
P
R
A
R
S
G
R
L
R
A
A
E
R
I
-
45
Fugue
88.67
42%
-72
- C1 -
1M6Y
2
RSMH_THEMA
A:
[4-296]
---
R
K
Y
S
Q
R
H
I
P
V
M
V
-
R
E
V
I
E
F
L
K
P
E
D
E
K
I
---
I
L
D
C
T
V
G
E
G
G
H
S
R
A
I
L
E
----
H
-
C
--
P
-
G
C
R
I
I
G
I
D
V
---------
D
S
E
-
V
L
R
I
A
E
E
----
K
L
K
E
--
F
S
------
D
R
V
S
-------------------
L
F
K
V
S
Y
R
--
E
-
A
D
F
L
---
L
-
K
T
L
-
G
-
I
E
K
V
D
G
I
L
M
D
L
G
V
S
T
Y
Q
L
K
G
E
N
R
G
F
T
F
-
E
R
-
E
E
P
L
D
M
R
M
D
L
E
--
S
E
V
T
A
Q
-
K
V
L
N
E
L
P
E
E
E
L
A
-
R
I
I
F
E
Y
G
E
--
E
K
-
R
F
A
-
R
R
I
A
R
K
I
V
E
N
R
P
L
N
T
T
L
D
-
L
V
K
A
V
R
E
A
L
P
S
Y
-
E
I
--
R
R
----
R
K
R
H
F
A
T
K
T
F
Q
A
I
R
I
Y
V
N
R
E
L
-
E
N
L
K
E
F
L
K
K
A
E
--------
D
LL
N
--
P
G
G
R
I
V
V
I
S
F
H
S
L
E
D
R
I
V
K
E
T
F
R
N
S
K
K
-------------------
L
R
--
I
L
T
E
K
P
V
R
P
S
E
E
E
-
I
R
E
N
P
R
A
R
S
G
R
L
R
A
A
E
R
I
-
24
HHSearch
88.64
39%
-77
- C1 -
1WG8
1
RSMH_THET8
A:
[4-283]
-------
M
T
H
V
P
V
-
L
Y
Q
E
A
L
D
L
L
A
V
R
P
G
G
V
---
Y
V
D
A
T
L
G
G
A
G
H
A
R
G
I
L
E
----
R
------
G
G
R
V
I
G
L
D
Q
---------
D
P
E
-
A
V
A
R
A
K
G
----
L
H
L
-----------
P
G
L
T
-------------------
V
V
Q
G
N
F
R
--
H
L
K
R
H
L
---
A
-
A
L
G
-
V
-
E
R
V
D
G
I
L
A
-
D
L
G
V
S
S
F
H
L
D
D
P
S
R
G
F
S
Y
-
Q
K
E
G
P
-
L
D
-
M
-
R
M
G
L
E
-
G
P
T
A
K
-
E
V
V
N
R
L
P
L
E
A
L
A
-
R
L
L
R
E
L
G
E
--
E
P
-
Q
-
A
-
Y
R
I
A
R
A
I
V
A
A
R
E
K
A
P
I
E
T
-
T
T
Q
L
A
E
I
V
--
R
K
A
V
G
--
F
R
----
R
A
G
H
P
A
R
K
T
F
Q
A
L
R
I
Y
V
N
D
E
L
-
N
A
L
K
E
F
L
E
Q
A
A
--------
E
V
L
A
--
P
G
G
R
L
V
V
I
A
F
H
S
L
E
D
R
V
V
K
R
F
L
R
E
S
G
--------------------
L
K
--
V
L
T
K
K
P
L
V
P
S
E
K
E
-
A
A
Q
N
P
R
A
R
S
A
K
L
R
A
A
E
K
E
A
21
PsiBlast_CBE
88.24
37%
-84
- C1 -
1WG8
1
RSMH_THET8
B:
[6-278]
---------
H
V
P
V
-
L
Y
Q
E
A
L
D
L
L
A
V
R
P
G
G
V
---
Y
V
D
A
T
L
G
G
A
G
H
A
R
G
I
L
E
----
R
-
G
--
G
---
R
V
I
G
L
D
Q
---------
D
P
E
-
A
--
V
A
R
A
----
K
G
L
H
--
L
P
------
G
-
L
T
-------------------
V
V
Q
G
N
F
R
H
L
K
R
H
L
A
A
---
L
-
G
V
----
E
R
V
D
G
I
L
A
-
D
L
G
V
S
S
F
H
L
D
D
P
S
R
G
F
S
Y
-
Q
K
-
E
G
P
L
D
-
M
-
R
M
G
L
E
G
P
-
T
A
K
-
E
V
V
N
R
L
P
L
E
A
L
A
-
R
L
L
R
E
L
G
E
--
E
P
-
Q
-
A
-
Y
R
I
A
R
A
I
V
A
A
R
E
K
A
P
I
E
T
-
T
T
Q
L
A
E
I
V
R
-
K
A
-
V
G
--
F
R
----
R
A
G
H
P
A
R
K
T
F
Q
A
L
R
I
Y
V
N
D
E
L
-
N
A
L
K
E
F
L
E
Q
A
A
--------
E
--
V
LA
P
G
G
R
L
V
V
I
A
F
H
S
L
E
D
R
V
V
K
R
F
L
R
E
---------
S
G
L
K
-------------
V
L
T
K
K
P
L
V
P
S
E
K
E
-
A
A
Q
N
P
R
A
R
S
A
K
L
R
A
A
E
K
E
A
3
PsiBlast_PDB
87.38
37%
-79
- C1 -
1WG8
1
RSMH_THET8
A:
[6-278]
---------
H
V
P
V
-
L
Y
Q
E
A
L
D
L
L
A
V
R
P
G
G
V
---
Y
V
D
A
T
L
G
G
A
G
H
A
R
G
I
L
E
----
R
-
G
--
G
---
R
V
I
G
L
D
Q
---------
D
P
E
-
A
--
V
A
R
A
----
K
G
L
H
--
L
P
------
G
-
L
T
-------------------
V
V
Q
G
N
F
R
H
L
K
R
H
L
A
A
---
L
-
G
V
----
E
R
V
D
G
I
L
A
-
D
L
G
V
S
S
F
H
L
D
D
P
S
R
G
F
S
Y
-
Q
K
-
E
G
P
L
D
-
M
-
R
M
G
L
E
G
P
-
T
A
K
-
E
V
V
N
R
L
P
L
E
A
L
A
-
R
L
L
R
E
L
G
E
--
E
P
-
Q
-
A
-
Y
R
I
A
R
A
I
V
A
A
R
E
K
A
P
I
E
T
-
T
T
Q
L
A
E
I
V
R
-
K
A
-
V
G
--
F
R
----
R
A
G
H
P
A
R
K
T
F
Q
A
L
R
I
Y
V
N
D
E
L
-
N
A
L
K
E
F
L
E
Q
A
A
--------
E
--
V
LA
P
G
G
R
L
V
V
I
A
F
H
S
L
E
D
R
V
V
K
R
F
L
R
E
---------
S
G
L
K
-------------
V
L
T
K
K
P
L
V
P
S
E
K
E
-
A
A
Q
N
P
R
A
R
S
A
K
L
R
A
A
E
K
E
A
52
Fugue
56.00
17%
-24
* C2 *
4B46
1
CETZ1_HALVD
A:
[1-367]
--
M
K
-
L
A
M
I
G
F
G
Q
-
A
G
G
K
V
V
D
K
F
V
E
Y
D
R
E
R
NAG
I
V
R
A
A
V
A
V
N
S
A
K
A
D
L
L
G
LKNI
P
-
K
--
D
-
Q
R
V
L
I
G
Q
S
R
VKGHGVGAD
N
E
L
-
G
A
E
I
A
E
E
----
D
I
D
E
--
V
Q
------
G
A
I
D
S
IPVHEVD
A
F
L
V
V
S
G
LGGG
T
G
S
G
G
A
P
--
V
L
A
K
H
L
---
K
-
R
I
Y
-
T
-
E
P
V
Y
G
L
G
I
-
L
P
G
--------
S
D
E
G
G
I
Y
-
T
L
-
N
A
-
A
R
-
S
-
F
Q
T
F
V
R
E
V
D
N
L
-
L
V
F
D
-------
N
-
D
A
W
R
K
T
G
E
S
V
Q
G
-
G
-
Y
-
D
E
I
N
E
E
I
V
N
R
F
G
V
-
L
F
G
S
-
V
V
D
S
S
E
I
I
--
N
T
-
L
A
--
G
G
----
G
----
V
S
T
V
G
Y
A
S
E
G
V
T
A
H
T
T
-
N
R
I
T
S
L
V
R
K
A
A
L
GRLTLPC
E
--
I
--
E
G
A
E
R
A
L
L
V
L
A
G
P
P
E
H
L
N
R
K
G
I
E
R
G
R
K
W
I
E
E
Q
T
G
S
M
E
V
R
G
G
D
Y
P
I
P
G
A
--
E
K
V
A
G
V
I
L
L
S
--
G
-
V
T
N
V
P
R
I
K
E
L
Q
Q
V
A
I
E
A
Q
D
43
HHSearch
50.44
19%
-52
- C1 -
1NV8
2
PRMC_THEMA
A:
[111-205]
--------------
L
V
E
L
A
L
E
L
I
R
K
Y
G
I
K
T
---
V
A
D
I
G
T
G
S
G
A
I
G
V
S
V
A
K
------
F
--
S
-
D
A
I
V
F
A
T
D
V
---------
S
S
K
-
A
V
E
I
A
R
K
----
N
A
E
R
--
H
G
VS----
D
R
F
F
-------------------
V
R
K
G
E
F
L
--
E
P
F
K
E
--------
K
-
F
-
A
S
I
E
M
I
L
S
-
N
P
P
Y
V
K
S
S
A
H
L
P
K
D
V
L
F
E
-
P
P
-
E
A
-
L
F
-
G
-
G
E
D
G
L
D
F
Y
R
E
F
-
F
G
R
Y
D
T
S
G
K
I
V
L
-
M
E
I
G
E
D
Q
V
--
E
E
-
L
-
K
-
K
I
V
S
D
T
V
F
L
K
D
S
A
G
K
Y
R
F
-
L
L
L
N
R
R
S
S
-------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
49.41
24%
-51
- C1 -
3JWG
1
?
A:
[17-118]
--------------
R
L
G
T
V
V
A
V
L
K
S
V
N
A
K
K
---
V
I
D
L
G
C
G
E
G
N
L
L
S
L
L
L
K
----
D
-
K
--
S
-
F
E
Q
I
T
G
V
D
V
---------
S
Y
S
-
V
L
E
R
A
K
D
----
R
L
K
I
--
D
R
LP
E
M
Q
R
K
R
I
S
-------------------
L
F
Q
S
S
L
V
--
Y
R
D
K
R
----------
F
-
S
G
Y
D
A
A
T
V
---
I
E
V
I
E
H
L
D
E
N
R
L
Q
A
F
E
-
K
V
-
L
F
-
E
F
-
T
-
R
P
Q
T
V
I
V
S
T
P
N
-
K
E
Y
N
F
H
Y
G
N
L
R
H
-
R
D
H
R
F
E
W
T
--
R
K
-
E
-
F
-
Q
T
W
A
V
K
V
A
E
K
Y
G
Y
S
V
R
F
L
-
Q
I
G
E
I
D
D
E
--
F
G
-
S
P
--
T
Q
----
M
G
V
F
T
L
G
A
--------------------------------------------------------------------------------------------------------------------------
44
HHSearch
48.72
22%
-30
- C1 -
3EEY
2
?
A:
[20-105]
------------------------
V
K
E
G
D
T
---
V
V
D
A
T
C
G
N
G
N
D
T
A
F
L
A
S
----
L
-
V
G-
E
-
N
G
R
V
F
G
F
D
I
---------
Q
D
K
-
A
I
A
N
T
T
K
----
K
L
T
D
--
L
N
LI----
D
R
V
T
-------------------
L
I
K
D
G
H
Q
--
N
M
D
K
Y
I
---------
D
-
C
P
V
K
A
V
M
F
-
N
L
G
Y
L
P
S
G
D
H
S
I
S
T
R
P
E
T
-
T
I
-
Q
A
-
L
S
-
K
-
A
M
E
L
L
V
T
G
G
I
I
-
T
V
V
I
Y
Y
G
G
D
T
G
F
-
E
E
K
E
K
V
L
E
--
F
L
-
K
-
G
-
V
D
Q
K
K
F
I
V
Q
R
T
D
F
I
N
Q
A
N
-
C
P
P
I
L
V
C
I
--
E
K
-
I
S
--
E
G
----
H
H
H
H
H
H
----------------------------------------------------------------------------------------------------------------------------
48
Fugue
48.24
12%
-30
- C1 -
2P35
1
TAM_AGRFC
A:
[8-259]
AQ
Q
Y
L
K
F
E
D
E
R
T
R
-
P
A
R
D
L
L
A
Q
V
P
L
E
R
V
L
N
---
G
Y
D
L
G
C
G
P
G
N
S
T
E
L
L
T
D
----
R
-
Y
--
G
-
V
N
V
I
T
G
I
D
S
---------
D
D
D
M
L
E
K
A
A
D
R
----
L
--------------------------------------------------------------
P
N
T
N
F
G
K
A
-
D
L
A
T
W
K
P
---
A
Q
K
A
D
L
L
Y
-
A
N
-
A
V
-
F
Q
-
W
-
V
P
D
H
L
A
V
L
S
Q
L
M
D
Q
L
E
S
G
G
V
L
A
V
Q
M
P
D
N
L
Q
-
E
P
--
T
H
-
I
-
A
M
H
E
T
A
D
G
G
P
W
K
D
A
F
K
P
L
P
P
-
P
S
D
Y
F
N
A
L
--
S
P
-
K
S
--
S
R
----
V
D
V
W
H
T
V
Y
N
H
----------
P
M
K
D
A
D
S
I
V
E
W
V
K
--------
G
--
T
--
G
L
R
P
Y
L
A
A
A
G
E
E
N
R
E
A
F
L
A
D
Y
T
R
R
I
A
A
A
Y
--------------------------------
P
P
M
A
D
G
R
L
L
L
R
F
P
R
L
F
V
V
A
V
K
K
41
HHSearch
47.67
14%
-51
- C1 -
1O54
1
?
A:
[104-191]
------------------
I
A
M
M
L
D
V
K
E
G
D
R
---
I
I
D
T
G
V
G
S
G
A
M
C
A
V
L
A
R
----
A
-
V
--
G
S
S
G
K
V
F
A
Y
E
K
---------
R
E
E
-
F
A
K
L
A
E
S
----
N
L
T
K
--
W
G
LI----
E
R
V
T
-------------------
I
K
V
R
D
I
S
--
E
G
F
------
D
-----
E
-
K
D
V
D
A
L
F
L
-
D
V
P
D
P
W
N
Y
I
D
K
C
W
E
A
L
K
G
-
G
G
-
R
F
-
A
T
-
V
-
C
P
T
T
N
Q
V
Q
E
T
L
-
K
K
L
Q
E
L
P
F
I
R
I
E
-
V
W
E
S
L
F
R
P
--
Y
K
-
P
-
V
-
P
E
R
L
R
P
V
D
R
M
V
A
H
T
A
Y
M
I
-
F
A
T
K
V
C
R
R
--
E
E
---------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
47.28
11%
-54
- C1 -
3E05
2
?
A:
[28-119]
--------------
V
R
A
V
T
L
S
K
L
R
L
Q
D
D
L
V
---
M
W
D
I
G
A
G
S
A
S
V
S
I
E
A
S
N
----
L
-
M
--
P
-
N
G
R
I
F
A
L
E
R
---------
N
P
Q
-
Y
L
G
F
I
R
D
----
N
L
K
K
--
F
V
A-----
R
N
V
T
-------------------
L
V
E
A
F
A
P
--
E
G
L
D
D
----------
L
-
P
D
P
D
R
V
F
I
-
G
G
S
G
G
M
L
E
E
I
I
D
A
V
D
R
R
L
-
K
S
-
E
G
-
V
I
-
V
-
L
N
A
V
T
L
D
T
L
T
K
-
A
V
E
F
L
E
D
H
G
Y
M
V
-
E
V
A
C
V
N
V
A
--
K
T
-
K
-
E
-
Y
K
M
F
E
S
H
N
P
V
Y
I
I
T
A
W
K
S
----------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
46.99
14%
-17
- C1 -
4PON
-
?
A:
[7-197]
------
M
I
L
K
K
I
L
-
P
Y
S
K
E
L
L
K
M
A
A
G
E
G
D
I
---
V
I
D
A
T
M
G
-
N
G
H
D
T
Q
F
L
A
----
E
-
L
V
G
E
-
N
G
H
V
Y
A
F
D
I
---------
Q
E
S
-
A
V
A
N
T
K
E
----
R
L
G
E
--
A
Y
------
Q
A
R
T
-------------------
T
L
F
H
K
S
H
--
D
K
I
A
K
S
---
L
P
P
E
T
-
H
-
G
K
V
A
A
A
V
F
-
N
L
G
N
G
S
S
T
I
K
A
I
E
Q
L
L
S
I
-
M
K
-
D
E
-
G
L
-
I
-
V
L
V
V
Y
H
G
N
D
V
L
-
D
F
C
R
N
L
D
Q
Q
A
A
R
-
V
L
T
Y
G
F
I
N
--
Q
Q
-
N
-
D
-
P
P
F
I
V
A
I
E
K
K
A
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
46.76
14%
-5
- C1 -
3EEY
6
?
A:
[3-197]
------
L
T
I
K
N
S
L
-
G
Q
S
H
D
Y
I
K
M
F
V
K
E
G
D
T
---
V
V
D
A
T
C
G
N
G
N
D
T
A
F
L
A
S
----
L
V
G
--
E
-
N
G
R
V
F
G
F
D
I
---------
Q
D
K
-
A
I
A
N
T
T
K
----
K
L
T
D
L
N
L
I
------
D
R
V
T
-------------------
L
I
K
D
G
------
H
Q
N
M
---
D
-
K
Y
I
-
D
-
C
P
V
K
A
V
M
F
-
N
L
G
Y
L
P
---
S
G
D
H
S
I
S
T
R
-
P
E
-
T
T
-
I
Q
-
A
-
L
S
K
A
M
E
L
L
V
T
G
-
G
I
I
T
V
V
I
Y
Y
G
G
D
-
T
G
F
E
E
K
E
K
--
V
L
-
E
-
F
-
L
K
G
V
D
Q
K
K
F
I
V
Q
R
T
D
F
I
N
-
Q
A
N
C
P
P
I
L
--
V
C
-
I
E
--
K
I
----
S
E
G
H
H
H
H
H
H
-------------------------------------------------------------------------------------------------------------------------
34
HHSearch
45.46
12%
-47
- C1 -
1DL5
1
PIMT_THEMA
A:
[56-154]
------
S
T
S
S
Q
P
S
-
L
M
A
L
F
M
E
W
V
G
L
D
K
G
M
R
---
V
L
E
I
G
G
G
T
G
Y
N
A
A
V
M
S
R
----
V
-
V
--
G
E
K
G
L
V
V
S
V
E
Y
---------
S
R
K
-
I
C
E
I
A
K
R
----
N
V
E
R
--
L
G
I-----
E
N
V
I
-------------------
F
V
C
G
D
G
Y
--
Y
G
V
P
---------
E
-
F
-
S
P
Y
D
V
I
F
V
-
T
V
G
V
D
E
V
P
E
T
W
F
T
Q
L
K
E
G
-
G
R
-
V
I
-
V
P
-
I
-
N
L
K
L
S
R
R
Q
P
A
F
-
L
F
K
K
K
D
P
Y
L
V
G
N
-
Y
K
L
E
T
R
F
I
--
T
A
-
G
-
G
-
N
L
G
N
L
L
E
R
N
R
K
L
L
R
E
F
P
F
-
N
R
E
I
L
L
V
R
--
S
H
-
I
F
--
V
E
----
L
V
D
L
L
T
R
R
L
T
E
I
D
G
T
F
Y
Y
A
G
P
-
N
G
V
V
E
F
L
D
D
R
M
--------
R
--
I
--
Y
G
D
A
P
E
I
E
N
L
L
T
Q
W
E
S
C
G
Y
R
S
F
E
Y
L
M
L
H
V
G
Y
N
A
F
S
H
I
S
C
S
I
------------------------------------------
37
HHSearch
44.29
18%
-23
- C1 -
1YZH
-
TRMB_STRPN
A:
[35-120]
--------------------
R
D
L
F
G
N
D
N
P
I
---
H
V
E
V
G
S
G
K
G
A
F
V
S
G
M
A
K
----
Q
-
N
--
P
-
D
I
N
Y
I
G
I
D
I
---------
Q
K
S
-
V
L
S
Y
A
L
D
----
K
V
L
E
--
V
G
V-----
P
N
I
K
-------------------
L
L
W
V
D
G
S
--
D
L
T
D
Y
F
---
E
-----
D
-
G
E
I
D
R
L
Y
L
-
N
F
S
D
P
W
P
K
K
R
H
E
K
R
R
L
T
Y
-
K
T
-
F
L
-
D
T
-
F
-
K
R
I
L
P
E
N
G
E
I
H
-
F
K
T
D
N
R
G
L
F
E
Y
S
-
L
V
S
F
S
Q
Y
G
--
M
K
-
L
-
N
-
G
V
W
L
D
L
H
A
S
D
F
E
G
N
V
M
T
E
-
Y
E
Q
K
F
S
N
K
--
G
Q
-
V
I
--
Y
R
----
V
E
A
E
F
-----------------------------------------------------------------------------------------------------------------------------