@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0772: (2015-12-18 )
MFLVKKIGVVIMILVCFLACSQESFIKMQKKAQEQENDGSKRPSYVDSDYEVFSETIFLQNMVYQPIEERNAFFQLTKDEDNSFNPENSVILLNEPSDNSEKNLLSYPNDPNNNEDNANNSQKNPFLYKPKRKTKNPKLIEYSQQDFYPLKNGDIIMSKEGDQWLIEIQSKALKRFLKDQNDKDRQIQTFTFNDTKTQIAQIKGKISSYVYTTNNGSLSLRPFYESFLLEKKSDNVYTIENKALDTMEISKCQMVLKKHSTDKLDSQHKAISIDLDFKKERFKSDTELFLECLKES
Atome Classification :
(18 SA)
-----------------------------------------------------.----....------....-------10.....---...20........-30.....-...40...------.---------....50----------------------..---.....-------------------.------.60-.........70.--....-...80------------..-......---90........-100.......--------110-.........120......-----.------130.------......140--..---------....-...----150......-.160.......170--.....---------...180----..-......190.......200-..-----.-------------...-..------210......----...220----.........-------------------230.-......240......-.250-.......260........270...---------------....280...------.....290....----------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------M----
F
L
V
K
------
K
I
G
V
-------
V
I
M
I
L
V
C
---
F
L
ACS
Q
E
S
F
I
K
M
Q
-
K
K
A
Q
EQE-NDGSKRPS------Y---------VD
S
D
Y
-----------------------
E
V
---
F
S
E
T
I
-------------------
F
------
L
Q
--
N
M
V
YQ
P
I
E
ERN
A
--
F
F
Q
L
-TKDED------------NS-FNPEN
S
---
V
I
L
L
NEPSDN-SEKNLLSYPN--------D---PNNNEDNANNSQKNP
F
L
Y-----K------PKRK------TKNP
K
L
I
----
E
Y---------SQQD-
F
Y
P----LKNG
D
I
I
MS-KEG
D
Q
W
L
I
E
I
Q
S
K
---
A
L
K
R
F
---------
L
KDQN-----DK-D
R
Q
I
Q
T
F
T
FNDT
K
T
Q
I
A
Q
--
I
K-----G-------------K
I
S
-
S
Y
------
V
--
Y
TTNNG----
S
L
S
L
------
R
P
F
Y
E
S
F
L
L
-------------------EKKS-D
N
V
Y
T
IENKAL
D
T
M
E
-
I
S
K
C
-
Q
M
V
L
K
KHST-DKLDSQH
K
A
I
S
I
D
L---------------D
F
K
K
E
-
R
FK
S
------
D
T
E
L
F
L
E
C
L
KES----------------------------
12
Fugue
85.56
20%
-12
* C9 *
1SQ9
2
SKI8_YEAST
A:
[3-395]
-----------------------------------------------------
K
----
V
F
I
A
------
T
A
N
A
GKAHDAD
I
F
S
V
S
A
C
NS
F
T
V
S
C
S
G
D
G
Y
L
K
V
W
D
N
K
L
L
D
N
E
-
N
P
K
D
K
S
Y
S
------
H
F
V
H
KSGLH
H
V
D
V
L
Q
-----------------------
A
I
---
E
R
D
A
F
-------------------
E
------
L
C
--
L
V
A
T
T
S
F
S
G
D
L
L
--
F
Y
R
I
-
T
R
E
D
E
TK
K
V
I
F
E
K
L
DLL
D
S
-
D
M
K
K
H
S
---
F
W
A
L
K
W
G
A
S
N
-
S
H
R
L
V
A
T
D
V
K
G
T
T
Y
I
W
K
F
H
---
P
F
A
D
E
S
N
S
L
T
L
N
W
S
P
T
L
E
-----
L
Q
G
T
V
E
S
P
M
T
P
------
S
Q
F
A
T
S
V
----
D
I
---------
S
E
R
------------
G
L
I
A
T
G
F
N
N
G
T
V
Q
I
S
E
L
S
T
L
---
R
P
L
Y
N
---------
F
E
S
Q
H
-----
N
N
-
S
N
S
I
R
S
V
K
F
S
P
Q
G
S
L
L
A
I
--
A
H
D
S
NS
F
G
-------------
C
I
T
-
L
Y
------
E
TE
F
G
E
R
I
G
----
S
L
S
V
PGEFAH
S
S
W
V
M
S
L
S
F
N
DSGE
T
L
C
S
A
G
WDG
K
L
R
F
W
D
V
K
T
-
K
E
R
I
T
T
L
N
M
H
C
D
D
I
E
-
I
E
E
D
-
I
L
A
V
D
E
H
G
-----
D
S
L
A
E
P
G
V
F
D
V
---------------
K
F
L
K
K
-
G
W
R
S
GMGADL
N
E
S
L
C
C
V
C
L
D
R
S
I
R
W
F
R
E
A
G--------------------
17
Fugue
73.60
16%
5
- C9 -
3WJ9
-
EIF2A_SCHPO
A:
[3-412]
QKS
Q
F
A
Y
R
S
SK
S
I
G
L
V
NASENYASPPK
F
E
A
I
SEPAR
N
A
C
Y
S
PNGK
L
F
A
Y
A
T
AT
Q
----
V
V
I
N
D
TESGA
K
L
T
Q
-------
L
P
A
A
N
T
Y
---
E
L
G
F
S
P
L
G
K
Y
L
S
T
-
W
E
R
P
G
K
E
-
A
D
G
T
P
K
Q
N
M
-----
K
---------
V
W
N
-------------------------------
T
E
T
----------------------------
G
--
Q
L
V
F
S
F
V
Q
R
N
Q
T
GW
N
L
Q
Y
-
T
C
D
E
S
------------
L
A
-
A
R
L
V
T
N
---
E
V
H
F
Y
E
-
T
G
N
M
S
K
G
P
I
A
K
L
R
V
--------
E
---
G
I
S
D
F
A
L
S
P
G
Q
N
H
A
V
A
V
F
-----
I
------
P
E
K
K
------
G
A
P
A
S
V
R
----
T
Y
S
IPNFNSPL
S
Q
K
T
-
F
F
K
----
A
D
K
V
Q
F
K
W
N
-
A
L
G
T
S
L
L
V
L
T
Q
D
K
---
S
N
K
N
Y
---------
Y
G
E
T
T
GQFDL
D
R
-
E
G
P
I
H
D
V
C
W
N
A
D
S
K
E
F
G
I
--
V
Y
-----
G
YMP
A
K
T
A
I
F
D
NRA
N
V
V
-
S
I
------
I
--
P
P
A
P
R
N
----
T
L
I
F
------
S
P
N
S
R
Y
I
L
L
A
G
F
GNLQ
G
S
I
D
I
F
D
-----
A
A
N
N
M
K
K
I
T
T
V
E
A
A
N
C
T
Y
C
E
-
F
S
P
D
S
Q
F
L
L
T
A
V
T
S
-
P
R
L
R
V
D
N
-
S
I
K
I
W
H
---------------
I
T
G
A
P
M
F
Y
E
E
------
F
N
E
L
Y
Q
A
F
W
R
P
R
PLN-------------------------
14
Fugue
66.92
16%
5
- C3 -
4OO3
-
?
A:
[3-441]
--------------------------------EGFTGAPGE
V
K
L
I
T
L
DPGH
F
H
A
----
A
L
V
Q
------
K
V
S
Y
-------
P
Q
V
S
K
D
V
---
Y
V
Y
A
P
T
G
F
D
V
D
E
H
-
L
K
R
I
Q
G
F
-
N
T
R
A
E
N
P
T
A
W
N
E
I
V
Y
---------
T
G
D
D
Y
L
E
K
M
L
A
E
KKGN
V
M
I
Q
A
G
NNGK
K
T
E
Y
---
I
K
K
T
L
E
A
G
I
N
V
L
S
D
K
PMAIN
S
Q
S
F
K
------
L
L
--
E
E
C
F
A
I
A
K
Q
K
N
I
M
-
L
Y
D
I
M
T
E
R
N
E
I
-----------
T
T
M
L
Q
R
E
L
S
T
IP
A
V
Y
G
E
Q
L
K
G
S
-
P
E
E
P
A
I
V
K
E
S
--------
V
---
H
H
L
F
K
L
V
D
N
K
P
L
T
R
P
V
W
Y
-----
L
------
D
V
N
Q
QGEGIV
D
V
T
T
H
L
V
----
D
L
---------
V
Q
W
E
-
A
F
P
DQI-
I
D
Y
R
K
D
I
E
L
-
I
D
A
N
R
W
T
T
S
I
S
P
E
---
E
F
K
Q
V
TGTDAYPDF
L
K
K
D
V
-----
E
N
-
D
-
T
L
K
V
Y
C
N
G
D
I
V
Y
K
I
K
G
--
V
T
-----
A
-------------
K
V
S
V
I
W
------
N
--
Y
T
F
P
K
G
G
G
D
T
H
F
S
V
M
-----
K
G
S
K
A
D
L
V
I
-------------------
R
Q
G
K
-
E
Q
N
Y
Q
P
E
L
F
V
E
A
V
K
G
-
V
D
L
A
-
A
Y
E
K
D
L
T
A
S
M
E
K
V
S
A
E
Y
P
G
V
A
L
N
K
VGDG
V
W
Q
V
E
I
P
AKYR
V
G
H
E
A
-
H
F
G
Q
------
V
T
E
H
F
L
D
Y
L
K
E
G
KLPDW
E
V
P
N
M
L
A
K
Y
Y
T
T
T
S
A
L
D
M
A
K
A
K
T
2
PsiBlast_PDB
57.81
23%
24
- C5 -
4OBM
2
?
A:
[105-251]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
E
L
F
D
M
-
V
G
N
T
T
L
T
V
P
S
--------
E
IKY
E
N
K
K
D
N
T
V
T
I
I
K
K
G
T
Q
I
F
-----
T
------
A
E
Q
M
------
Y
A
Y
L
T
L
P
----
D
Y
---------
G
V
K
D
E
L
Y
P
----
C
K
L
N
A
T
V
I
S
-
S
F
I
D
Q
N
F
I
G
T
S
S
K
---
T
L
D
E
Y
---------
I
-----------------
N
F
I
I
N
F
T
N
T
N
I
E
Q
S
D
Y
D
-----
A
-------------
K
V
K
-
A
I
------
V
--
Y
T
L
S
Q
N
----
K
S
S
V
------
T
D
F
Y
I
P
Y
---------------------
G
D
K
S
-
G
D
D
Y
I
I
D
D
N
S
W
N
S
A
K
-
K
A
L
G
-
T
G
---------------------------------------------------------------------------------------------
20
Fugue
50.13
12%
19
- C4 -
4R1D
-
?
B:
[1-301]
-----------------------------------------------------
M
DKTG
W
I
T
H
------
C
F
G
R
-------
F
L
I
D
L
P
----
P
D
A
V
I
N
A
G
Y
Y
L
W
G
-
D
R
I
E
Y
L
D
-
D
K
P
T
E
L
A
A
------
R
---------
V
D
R
L
E
-----------------------
Q
E
---
W
R
T
Q
R
-------------------
H
------
K
S
KG
N
M
F
L
R
K
I
D
F
G
N
E
--
S
V
G
L
-
L
S
W
S
S
------------
E
V
---
A
S
K
T
---
Y
L
L
D
T
Y
V
T
S
K
-
P
T
W
H
V
Y
R
W
K
G
--------
K
---
V
S
V
D
R
E
Q
H
A
V
E
I
S
R
A
L
A
R
N
L
R
S
R
A
------
P
K
E
I
------
P
S
E
P
G
F
C
I
DHA
Y
I
---------
A
G
D
S
-
F
Q
V
----
E
R
F
G
V
G
V
T
F
-
P
E
H
P
G
A
R
F
E
F
R
S
S
T
G
A
E
L
N
S
L
---------
L
E
R
V
D
-----
G
F
V
Q
N
M
L
S
T
F
A
G
M
E
T
L
R
K
G
K
H
--
P
V
-----
G
-------------
S
L
P
-
G
E
------
E
--
Y
L
V
A
G
S
----
D
K
G
Q
------
R
G
Y
--
T
F
M
W
-------------------
E
V
Q
G
-
K
E
E
S
L
T
E
P
N
L
T
A
G
L
A
-
V
L
E
R
-
S
N
E
N
G
K
P
P
P
-
P
A
F
K
S
D
K
E
A
L
E
L
W
D
---------------
T
I
V
D
S
-
I
R
V
R
------
P
T
S
-------------------------------------
15
Fugue
48.39
11%
33
* C7 *
2KNR
-
?
A:
[1-118]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
---
L
K
S
E
M
-------------------
F
------
V
S
--
A
L
I
R
R
V
F
A
A
G
G
F
--
A
A
V
E
-
K
K
G
A
E
------------
A
A
-----
G
A
---
I
F
V
R
Q
R
L
R
D
G
-
R
E
N
L
Y
G
P
A
P
Q
--------
S
---
F
A
D
D
E
D
I
M
R
A
E
R
R
F
E
T
R
L
-----
A
------
G
V
E
G
------
E
E
I
A
A
L
L
----
E
R
---------
E
R
R
F
-------------------
D
S
D
L
W
V
V
E
I
E
T
D
---
E
I
G
T
L
---------
L
T
L
V
D
-----
Q
P
-
Q
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
46.90
20%
55
- C7 -
3WOE
-
?
B:
[3-106]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
P
Y
I
R
L
F
E
A
-----
I
------
P
D
A
E
------
T
E
L
A
T
F
Y
----
D
A
---------
D
L
D
T
-
L
P
P
R
M
F
-
L
P
S
G
D
L
-
Y
T
-
P
P
G
P
V
R
L
E
E
I
K
R
K
---
R
R
V
R
L
---------
V
K
V
S
I
-----
Y
R
-
F
E
H
V
G
L
G
---------
L
A
--
A
R
-----
P
-------------
Y
A
Y
-
A
Y
------
A
--
W
Q
G
D
N
G
----
I
L
H
L
--------
Y
H
A
P
V
V
L
-------------------
E
D
-----------------------------------------------------------------------------------------------------------------------
16
Fugue
40.87
17%
7
- C5 -
4CU5
-
?
A:
[1-85]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
K
H
T
I
V
Y
D
G
---
E
V
D
K
--
I
S
-----
A
-------------
T
V
V
-
G
W
------
G
--
Y
--
N
D
G
----
K
I
L
I
------
C
D
I
K
D
--
Y
V
-------------------
P
G
Q
T
-
Q
N
L
Y
V
V
G
G
G
A
C
E
K
I
S
S
I
T
K
E
-
K
F
I
M
I
K
-
G
N
-
D
R
F
D
T
L
Y
K
A
L
D
F
I
N
---------------
R
-------------------------------------------------------
13
Fugue
38.31
12%
31
* C5 *
2KJK
-
?
A:
[1-100]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
K
------
V
T
Y
D
G
V
Y
----
V
L
---------
S
V
K
E
-
D
V
P
AAGI
L
H
A
G
D
L
I
T
E
-
I
D
G
Q
S
F
K
---
S
S
Q
---
E
F
I
D
Y
---------
I
H
S
K
K
-----
V
G
-
D
T
V
K
I
K
Y
K
H
G
N
K
N
E
E
A
S
I
--
K
L
-----
T
-------------
A
I
D
-
K
K
G
T
P
G
I
G
I
--
T
L
V
D
D
L
----
E
H
H
H
------
H
H
H
--------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
36.04
14%
-42
- C5 -
2B78
-
?
A:
[324-384]
----------------------------------------------------------------------
N
G
-------
L
I
I
A
S
T
N
---
A
A
N
M
T
V
S
Q
F
K
K
Q
I
-
E
K
G
F
G
K
Q
K
H
T
Y
-
L
D
L
Q
------
Q
---------
L
P
S
D
F
-----------------------
A
V
NVQ
D
E
S
S
N
-------------------
Y
------
L
K
--
V
F
T
I
K
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
35.50
29%
-27
* C8 *
4FL0
1
ALD1_ARATH
A:
[167-223]
---------------------------------------------------------------------------------------------------------------------
P
A
------
Y
---------
I
D
S
S
V
-----------------------
I
I
---
G
Q
T
G
H
-------------------
F
HEKTKK
Y
Q
--
N
V
V
Y
M
P
C
G
P
N
N
S
--
F
F
------
P
D
------------
L
A
-
M
T
P
R
T
D
---
V
I
F
F
C
S
P
N
N
P
-
T
G
Y
V
A
S
R
K
Q
L
--------
H
---
Q
L
V
D
F
A
K
T
N
G
S
I
I
I
F
D
S
A
-----
Y
------
A
A
F
I
------
E
D
G
S
P
R
S
----
I
Y
---------
E
I
P
G
-
A
R
E
----
V
A
I
E
V
S
S
F
S
-
K
F
A
G
F
T
G
V
R
L
G
W
S
---
I
I
P
D
E
---------
L
L
Y
S
N
-----
G
F
-
P
I
I
N
D
F
H
R
I
V
T
T
S
F
N
G
A
S
--
N
I
-----
A
-------------
Q
A
G
-
G
L
------
A
--
C
L
S
S
G
G
----
L
K
E
I
------
R
S
V
N
N
Y
Y
K
E
-------------------
N
R
K
I
-
L
M
D
T
L
V
S
L
G
L
K
V
Y
G
G
-
V
N
A
P
-
Y
L
W
V
H
F
K
G
S
-
K
S
W
D
V
F
N
E
I
L
E
N
T
H
---------------
I
I
T
V
P
-
G
S
G
F
------
G
P
G
G
E
E
Y
L
R
I
S
G
----------------------------
10
HHSearch
31.28
63%
657
- C2 -
2LXT
-
C:
[13-20]
-----------------------------------------------------------------------------------------------------------------
L
S
R
R
P
S
------
Y
---------
R
K
I
L
N
-----------------------
D
L
---
S
S
D
A
P
-------------------
G
------
V
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
28.77
7%
77
* C6 *
3TND
-
VAPB_SHIFL
B:
[31-59]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
V
K
R
V
E
V
I
-
A
V
G
R
T
R
I
I
T
P
A
G
E
---
T
W
D
E
W
---------
F
D
G
H
S
-----
V
S
-
T
D
F
M
D
N
R
E
Q
P
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
26.00
42%
184
* C10 *
1B44
-
ELBH_ECOLX
D:
[14-32]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
T
Q
I
Y
T
--
I
N
-----
D
-------------
K
I
L
-
S
Y
------
T
--
E
S
M
A
G
K
----
R
E
M
V
------
I
I
T
F
K
S
G
A
T
-------------------
F
Q
V
E
-
V
P
G
S
Q
H
I
D
S
Q
K
K
A
I
E
-
R
M
K
D
-
T
L
R
I
T
Y
L
T
E
-
T
K
I
D
K
L
C
V
W
N
N
K
T
P
---------------
N
S
I
A
A
-
I
S
M
E
------
K
L
A
G
------------------------------------
7
HHSearch
25.77
21%
231
- C8 -
1BYY
-
SCN2A_RAT
A:
[1487-1505]
------------------------------------------------------------------------------------
D
I
---
F
M
T
E
E
Q
K
K
Y
Y
N
A
M
-
K
K
L
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
25.33
37%
155
- C10 -
3CHB
1
CHTB_VIBCH
D:
[15-33]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
T
Q
I
H
T
--
L
N
-----
D
-------------
K
I
F
-
S
Y
------
T
--
E
S
L
A
G
K
----
R
E
M
A
------
I
I
T
F
K
N
G
A
T
-------------------
F
Q
V
E
-
V
P
G
S
Q
H
I
D
S
Q
K
K
A
I
E
-
R
M
K
D
-
T
L
R
I
A
Y
L
T
E
-
A
K
V
E
K
L
C
V
W
N
N
K
T
P
---------------
R
A
I
A
A
-
I
S
M
A
------
N
---------------------------------------
6
HHSearch
23.51
71%
1260
- C1 -
1KDX
-
CREB1_RAT
B:
[128-134]
-----------------------------------------------------------------------------------------------------------------
L
S
R
R
P
S
------
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
13.43
47%
534
- C6 -
2LOX
-
B:
[22-33]
------------------------------------------------------------------------------------------------------------------------------------------
D
L
-----------------------
E
V
---
L
S
E
E
L
-------------------
F
------
E
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------