@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_1067: (2015-12-20 )
MMNEIIAVANQKGGVGKTTTAVNLAASLAAHEKKILLIDFDPQANATSSLGFRRDKIDYDIYHVLIGRKQISQVILKTQMPFLDLVPSNLGLAGFEKTFYDSQDENKRGELMLKNALGSVVKLYDYIIIDSPPALGPLTINSLSAAHSVIIPIQCEFFALEGTKLLLNTIRMLQKSTNPKLKIRGFLPTMHVPQLNLTKGVLAELFKYFDSEFFRDSATGEYIMIPKSVKLAESPSFGKPILLYDIKSNGSIAYQKLAQSILQG
Atome Classification :
(20 SA)
--------------....-----.....10........20........30........40-.-.-......50--....--.-----...60----........------.70......-..80........90........100-.......110.......120.-......130.......140.......150.......160........170........180.......190.......200.----......--210....---...220.-.-------.....230.....------..240.......250.......260..---------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------MMN
E
-----
I
I
A
V
ANQKGGVGK
T
T
T
A
V
N
L
A
A
S
L
AAHE
K
K
I
L
L
I
DFD-P-Q-ANATSSLG--FRRD--K-----I
D
Y
D
-----
I
Y
H
V
L
I
G
R
------
K
Q
I
S
Q
V
I
L
K
-TQM
P
F
L
D
LVPSNLGLAG
F
E
K
TFYDS-QDENKRG
E
L
M
L
K
N
A
L
G
S
V
V
K
L
-
Y
D
Y
I
I
IDSPPALG
P
L
T
INSLSAA
H
S
V
I
I
P
I
Q
C
E
F
F
AL-E
G
T
K
L
L
L
N
T
I
-
R
M
L
Q
KSTNP
K
L
K
I
R
G
FLPTMHVPQLN
L
T
K
G
V
L
A
----
E
L
F
K
Y
F
--
D
S
E
F
FRD---SATG
E
Y
I
-M-------IPKSVKLAESPSF------GK
P
I
L
L
Y
D
IKSNG
S
I
A
Y
Q
K
L
A
Q
S
I
LQG---------
3
PsiBlast_PDB
86.62
37%
-106
* C1 *
4PFS
-
?
A:
[9-257]
---------------
M
T
R
-----
V
L
A
V
A
N
Q
K
G
--
A
K
T
T
T
V
A
S
I
G
A
A
L
T
E
Q
G
R
R
V
L
L
V
D
L
D
-
P
-
Q
-
G
C
L
T
F
S
L
G
--
H
D
P
D
--
K
-----
L
P
V
S
-----
V
H
E
V
L
L
G
D
------
V
E
P
S
A
A
L
V
R
-
T
D
-
E
G
M
T
L
L
P
A
N
I
D
L
A
G
A
E
A
M
L
L
M
R
-
A
G
R
----
E
Y
A
L
K
R
A
L
A
K
L
D
G
D
-
F
D
V
V
I
I
D
C
P
P
S
L
G
V
L
T
L
N
G
L
T
A
A
H
D
V
I
V
P
L
Q
C
E
T
L
A
H
-
R
G
V
G
Q
F
L
R
T
I
-
S
D
V
Q
Q
I
T
N
P
D
L
K
L
L
G
A
L
P
T
L
Y
D
S
R
T
T
H
S
R
D
V
L
L
----
D
V
A
D
R
Y
--
E
L
P
V
L
A
P
---
P
---------------
I
P
R
T
-----------------------
R
K
S
K
G
A
I
A
Y
R
E
F
A
D
A
L
L
R
H
---------
22
PsiBlast_CBE
82.37
39%
-84
- C2 -
2BEK
3
SOJ_THET2
C:
[9-243]
------------------------
I
A
L
A
N
Q
K
G
G
V
G
K
T
T
T
A
I
N
L
A
A
Y
L
A
R
L
G
K
R
V
L
L
V
D
L
A
-
P
-
Q
-
G
N
A
T
S
G
L
G
--
V
R
A
E
--
R
--------
G
-----
V
Y
H
L
L
Q
G
E
PLEGLV
H
P
V
D
G
F
H
L
L
-
P
A
T
P
--
D
L
V
G
A
T
V
E
L
A
G
A
P
T
A
L
R
E
A
L
R
D
E
G
------------------
Y
D
L
V
L
L
D
A
P
P
S
L
S
P
L
T
L
N
A
L
A
A
A
E
G
V
V
V
P
V
Q
A
E
Y
Y
A
L
-
E
G
V
A
G
L
L
A
T
L
-
E
E
V
R
A
G
L
N
P
R
L
R
L
L
G
I
L
V
T
M
Y
D
G
R
T
L
L
A
Q
Q
V
E
A
----
Q
L
R
A
H
F
--
G
E
K
V
F
----------
W
T
-
V
-------
I
P
R
N
V
R
L
A
E
A
P
S
F
------
G
K
T
I
A
Q
H
A
P
T
S
P
G
A
H
A
Y
R
R
L
A
E
E
V
M
A
R
---------
21
PsiBlast_CBE
82.10
39%
-85
- C2 -
2BEK
3
SOJ_THET2
D:
[9-243]
------------------------
I
A
L
A
N
Q
K
G
G
V
G
K
T
T
T
A
I
N
L
A
A
Y
L
A
R
L
G
K
R
V
L
L
V
D
L
A
-
P
-
Q
-
G
N
A
T
S
G
L
G
--
V
R
A
E
--
R
--------
G
-----
V
Y
H
L
L
Q
G
E
PLEGLV
H
P
V
D
G
F
H
L
L
-
P
A
T
P
--
D
L
V
G
A
T
V
E
L
A
G
A
P
T
A
L
R
E
A
L
R
D
E
G
------------------
Y
D
L
V
L
L
D
A
P
P
S
L
S
P
L
T
L
N
A
L
A
A
A
E
G
V
V
V
P
V
Q
A
E
Y
Y
A
L
-
E
G
V
A
G
L
L
A
T
L
-
E
E
V
R
A
G
L
N
P
R
L
R
L
L
G
I
L
V
T
M
Y
D
G
R
T
L
L
A
Q
Q
V
E
A
----
Q
L
R
A
H
F
--
G
E
K
V
F
----------
W
T
-
V
-------
I
P
R
N
V
R
L
A
E
A
P
S
F
------
G
K
T
I
A
Q
H
A
P
T
S
P
G
A
H
A
Y
R
R
L
A
E
E
V
M
A
R
---------
2
PsiBlast_PDB
81.89
39%
-86
- C2 -
2BEK
3
SOJ_THET2
A:
[9-243]
------------------------
I
A
L
A
N
Q
K
G
G
V
G
K
T
T
T
A
I
N
L
A
A
Y
L
A
R
L
G
K
R
V
L
L
V
D
L
A
-
P
-
Q
-
G
N
A
T
S
G
L
G
--
V
R
A
E
--
R
--------
G
-----
V
Y
H
L
L
Q
G
E
PLEGL
V
H
P
V
D
G
F
H
L
L
-
P
A
T
P
--
D
L
V
G
A
T
V
E
L
A
G
A
P
T
A
L
R
E
A
L
R
D
E
G
------------------
Y
D
L
V
L
L
D
A
P
P
S
L
S
P
L
T
L
N
A
L
A
A
A
E
G
V
V
V
P
V
Q
A
E
Y
Y
A
L
-
E
G
V
A
G
L
L
A
T
L
-
E
E
V
R
A
G
L
N
P
R
L
R
L
L
G
I
L
V
T
M
Y
D
G
R
T
L
L
A
Q
Q
V
E
A
----
Q
L
R
A
H
F
--
G
E
K
V
F
----------
W
T
-
V
-------
I
P
R
N
V
R
L
A
E
A
P
S
F
------
G
K
T
I
A
Q
H
A
P
T
S
P
G
A
H
A
Y
R
R
L
A
E
E
V
M
A
R
---------
1
PsiBlast_PDB
81.89
39%
-84
- C2 -
2BEJ
2
SOJ_THET2
A:
[9-243]
------------------------
I
A
L
A
N
Q
K
G
G
V
G
K
T
T
T
A
I
N
L
A
A
Y
L
A
R
L
G
K
R
V
L
L
V
D
L
D
-
P
-
Q
-
G
N
A
T
S
G
L
G
--
V
R
A
E
--
R
--------
G
-----
V
Y
H
L
L
Q
G
E
PLEGL
V
H
P
V
D
G
F
H
L
L
-
P
A
T
P
--
D
L
V
G
A
T
V
E
L
A
G
A
P
T
A
L
R
E
A
L
R
D
E
G
------------------
Y
D
L
V
L
L
D
A
P
P
S
L
S
P
L
T
L
N
A
L
A
A
A
E
G
V
V
V
P
V
Q
A
E
Y
Y
A
L
-
E
G
V
A
G
L
L
A
T
L
-
E
E
V
R
A
G
L
N
P
R
L
R
L
L
G
I
L
V
T
M
Y
D
G
R
T
L
L
A
Q
Q
V
E
A
----
Q
L
R
A
H
F
--
G
E
K
V
F
----------
W
T
-
V
-------
I
P
R
N
V
R
L
A
E
A
P
S
F
------
G
K
T
I
A
Q
H
A
P
T
S
P
G
A
H
A
Y
R
R
L
A
E
E
V
M
A
R
---------
23
PsiBlast_CBE
81.52
39%
-82
- C2 -
2BEK
3
SOJ_THET2
B:
[9-243]
------------------------
I
A
L
A
N
Q
K
G
G
V
G
K
T
T
T
A
I
N
L
A
A
Y
L
A
R
L
G
K
R
V
L
L
V
D
L
A
-
P
-
Q
-
G
N
A
T
S
G
L
G
--
V
R
A
E
--
R
--------
G
-----
V
Y
H
L
L
Q
G
E
PLEGLV
H
P
V
D
G
F
H
L
L
-
P
A
T
P
--
D
L
V
G
A
T
V
E
L
A
G
A
P
T
A
L
R
E
A
L
R
D
E
G
------------------
Y
D
L
V
L
L
D
A
P
P
S
L
S
P
L
T
L
N
A
L
A
A
A
E
G
V
V
V
P
V
Q
A
E
Y
Y
A
L
-
E
G
V
A
G
L
L
A
T
L
-
E
E
V
R
A
G
L
N
P
R
L
R
L
L
G
I
L
V
T
M
Y
D
G
R
T
L
L
A
Q
Q
V
E
A
----
Q
L
R
A
H
F
--
G
E
K
V
F
----------
W
T
-
V
-------
I
P
R
N
V
R
L
A
E
A
P
S
F
------
G
K
T
I
A
Q
H
A
P
T
S
P
G
A
H
A
Y
R
R
L
A
E
E
V
M
A
R
---------
126
HHSearch
74.87
30%
-108
- C2 -
3K9G
12
?
A:
[26-266]
---------------
K
P
K
-----
I
I
T
I
A
S
I
K
G
G
V
G
K
S
T
S
A
I
I
L
A
T
L
L
S
K
-
N
N
K
V
L
L
I
D
M
D
-
T
-
Q
-
A
S
I
T
S
Y
F
Y
--
E
K
I
E
--
K
L
GINF
T
K
F
N
-----
I
Y
E
I
L
K
E
N
------
V
D
I
D
S
T
I
I
N
--
V
D
N
N
L
D
L
I
P
S
Y
L
T
L
H
N
F
S
E
D
K
I
-------
E
H
K
D
F
L
L
K
T
S
L
G
T
L
Y
Y
K
-
Y
D
Y
I
V
I
D
T
N
P
S
L
D
V
T
L
K
N
A
L
L
C
S
D
Y
V
I
I
P
M
T
A
E
K
W
A
V
-
E
S
L
D
L
F
N
F
F
V
-
R
K
L
N
L
----
F
L
-
P
I
F
L
I
I
T
R
F
K
K
N
R
-
T
H
K
T
L
F
E
----
I
L
K
T
----
K
D
R
F
L
-
G
-----------
T
-------
I
S
E
-------------------------
N
K
D
Y
I
K
E
Y
E
N
I
L
E
I
F
L
K
K
---------
19
PsiBlast_PDB
73.28
23%
-104
- C2 -
1HYQ
-
?
A:
[2-233]
----------------
V
R
-----
T
I
T
V
A
S
G
K
G
G
T
G
K
T
T
I
T
A
N
L
G
V
A
L
A
Q
L
G
H
D
V
T
I
V
D
A
D
I
T
-
M
-
A
N
L
E
L
I
L
G
--
M
--
E
--
G
-----
L
P
V
T
-----
L
Q
N
V
L
A
G
E
------
A
R
I
D
E
A
I
Y
--
V
G
P
G
G
V
K
V
V
P
A
G
V
S
L
E
G
L
R
K
A
N
P
E
K
-----------
L
E
D
V
L
T
Q
I
M
E
S
-
T
D
I
L
L
L
D
A
P
A
G
L
E
R
S
A
V
I
A
I
A
A
A
Q
E
L
L
L
V
V
N
P
E
I
S
S
I
T
D
G
L
K
T
K
I
V
A
E
-
R
L
-------
G
T
K
V
L
G
V
V
-------
V
N
R
I
T
T
L
G
I
----
E
M
A
K
N
E
--
I
E
A
I
L
E
A
---
K
V
I
G
----
L
-------
I
P
E
D
P
E
V
R
R
A
A
A
Y
------
G
K
P
V
V
L
R
S
P
N
S
P
A
A
R
A
I
V
E
L
A
N
Y
I
A
-----------
122
HHSearch
71.25
26%
-94
- C2 -
2OZE
3
?
A:
[35-288]
---------------
E
A
I
-----
V
I
L
N
N
Y
F
K
G
G
V
G
K
S
K
L
S
T
M
F
A
Y
L
T
D
K
L
N
L
K
V
L
M
I
D
K
D
-
L
-
Q
-
A
T
L
T
K
D
L
A
--
K
T
F
K
VE
L
-----
P
R
V
N
-----
F
Y
E
G
L
K
N
G
-------
N
L
A
S
S
I
V
H
--
L
T
D
N
L
D
L
I
P
G
T
F
D
L
M
L
L
P
K
L
T
R
S
W
---
T
F
E
N
E
S
R
L
L
A
T
L
L
A
P
L
K
S
D
-
Y
D
L
I
I
I
D
T
V
P
T
P
S
V
Y
T
N
N
A
I
V
A
S
D
Y
V
M
I
P
L
Q
A
E
E
E
S
T
-
N
N
I
Q
N
Y
I
S
Y
L
-
I
D
L
Q
E
Q
F
N
P
G
L
D
M
I
G
F
V
P
Y
L
V
D
T
D
S
A
T
I
K
S
N
L
E
----
E
L
Y
K
Q
H
K
E
D
N
L
V
F
Q
N
-----------
I
-------
I
K
R
S
N
K
V
S
T
W
S
K
N
------
G
I
T
E
H
K
G
Y
D
-
K
K
V
L
S
M
Y
K
N
V
F
F
E
M
L
E
R
---------
121
HHSearch
71.18
24%
-105
- C2 -
1HYQ
-
?
A:
[2-233]
----------------
V
R
-----
T
I
T
V
A
S
G
K
G
G
T
G
K
T
T
I
T
A
N
L
G
V
A
L
A
Q
L
G
H
D
V
T
I
V
D
A
D
-
I
-
T
M
A
N
L
E
L
I
L
G
--
M
E
G
L
---------
P
V
T
-----
L
Q
N
V
L
A
G
E
------
A
R
I
D
E
A
I
Y
V
--
G
P
G
G
V
K
V
V
P
A
G
V
S
L
E
G
L
R
-----------
K
A
N
P
E
K
L
E
D
V
L
T
Q
I
M
E
S
-
T
D
I
L
L
L
D
A
P
A
G
L
E
R
S
A
V
I
A
I
A
A
A
Q
E
L
L
L
V
V
N
P
E
I
S
S
I
-
T
D
G
L
K
T
K
I
V
A
-
E
R
L
------
G
T
K
V
L
G
V
V
V
N
R
I
T
T
L
G
I
--
E
M
A
K
N
----
E
I
E
A
I
L
--
E
A
K
V
I
G
------------
L
-------
I
P
E
D
P
E
V
R
R
A
A
A
Y
------
G
K
P
V
V
L
R
S
P
N
S
P
A
A
R
A
I
V
E
L
A
N
Y
I
A
-----------
140
Fugue
70.64
33%
-98
- C2 -
3K9G
12
?
A:
[26-267]
---------------
K
P
K
-----
I
I
T
I
A
S
I
K
G
G
V
G
K
S
T
S
A
I
I
L
A
T
L
L
S
-
K
N
N
K
V
L
L
I
D
M
D
-
T
-
Q
-
A
S
I
T
S
Y
F
Y
--
E
K
I
E
--
K
-----
L
G
I
N
FTKFN
I
Y
E
I
L
K
E
N
------
V
D
I
D
S
T
I
I
N
-
V
D
-
N
N
L
D
L
I
P
S
Y
L
T
L
H
N
F
------
S
-
E
D
K
I
E
H
K
D
F
L
L
K
T
S
L
G
T
L
Y
Y
K
-
Y
D
Y
I
V
I
D
T
N
P
S
L
D
V
T
L
K
N
A
L
L
C
S
D
Y
V
I
I
P
M
T
A
E
K
W
A
V
-
E
S
L
D
L
F
N
F
F
V
-
R
K
L
----
N
L
F
L
P
I
F
L
I
I
T
R
F
K
K
N
R
T
H
K
T
L
F
E
I
L
----
K
T
K
D
R
F
--
L
G
T
I
S
E
N
---
K
-----
D
-
Y
-------
I
K
E
Y
E
N
I
L
E
I
--
F
------
L
K
K
I
--------------------------------
16
PsiBlast_PDB
68.78
23%
-75
- C2 -
3Q9L
3
MIND_ECOLI
A:
[2-247]
----------------
A
R
-----
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
-
L
-
R
N
L
D
L
I
M
G
--
C
E
R
---
R
-----
V
V
Y
D
-----
F
V
N
V
I
Q
G
D
------
A
T
L
N
Q
A
L
I
K
-------
D
K
R
T
E
N
L
Y
I
L
P
A
S
Q
T
-
R
D
K
-
D
A
L
T
R
E
G
V
A
K
V
L
D
D
L
K
A
M
D
---
F
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
-
R
D
S
D
R
I
L
G
I
L
A
S
K
S
R
R
A
E
N
G
E
E
P
I
K
E
H
L
L
L
T
R
Y
N
P
G
R
V
S
R
G
D
M
L
----
S
M
E
D
V
L
----
E
I
L
R
I
---
K
L
V
G
----
V
-------
I
P
E
D
Q
S
V
L
R
A
S
N
Q
------
G
E
P
V
I
L
-
D
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
---------
144
Fugue
68.72
23%
-78
- C2 -
3Q9L
3
MIND_ECOLI
A:
[2-258]
----------------
A
R
-----
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
-
I
G
L
-
R
N
L
D
L
I
M
G
--
C
E
R
R
--
V
-----
V
-
Y
D
-----
F
V
N
V
I
Q
G
D
------
A
T
L
N
Q
A
L
I
K
D
K
R
T
E
N
L
Y
I
L
P
A
S
-----------
Q
T
-
R
D
K
D
A
L
T
R
E
G
V
A
K
V
L
D
D
L
K
A
M
D
F
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
-
R
D
S
D
R
I
L
G
I
L
A
S
K
S
R
R
A
E
N
G
E
E
P
I
K
E
H
L
L
L
T
R
Y
N
P
G
R
V
S
R
G
----------
D
M
L
--
S
M
E
D
V
L
E
---
I
L
R
I
K
L
V
G
V
-------
I
P
E
D
Q
S
V
L
R
A
S
N
Q
------
G
E
P
V
I
L
-
D
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
E
R
P
FRFIEE
119
HHSearch
68.51
25%
-98
- C2 -
1G3Q
2
?
A:
[1-235]
---------------
M
G
R
-----
I
I
S
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
-
L
-
T
M
A
N
L
S
L
V
L
G
--
V
D
D
P
---------
D
V
T
-----
L
H
D
V
L
A
G
E
------
A
N
V
E
D
A
I
Y
M
-
T
Q
F
D
N
V
Y
V
L
P
G
A
V
D
W
E
H
V
-----------
L
K
A
D
P
R
K
L
P
E
V
I
K
S
L
K
D
K
-
F
D
F
I
L
I
D
C
P
A
G
L
Q
L
D
A
M
S
A
M
L
S
G
E
E
A
L
L
V
T
N
P
E
I
S
C
L
-
T
D
T
M
K
V
G
I
V
L
-
K
K
A
------
G
L
A
I
L
G
F
V
L
N
R
Y
G
R
S
D
R
D
I
--
P
P
E
----
A
A
E
D
V
M
--
E
V
P
L
L
-
A
-----------
V
-------
I
P
E
D
P
A
I
R
E
G
T
L
E
------
G
I
P
A
V
K
Y
K
P
E
S
K
G
A
K
A
F
V
K
L
A
E
E
I
E
K
L
---------
139
Fugue
68.25
25%
-83
- C2 -
2OZE
3
?
A:
[15-298]
ME
K
E
E
L
K
I
L
E
E
L
R
R
I
L
S
N
K
N
E
A
I
V
I
L
N
N
Y
F
K
G
G
V
G
K
S
K
L
S
T
M
F
A
Y
L
T
D
K
L
N
L
K
V
L
M
I
D
K
D
-
L
-
Q
-
A
T
L
T
K
D
L
A
K
T
F
K
V
E
--
L
-----
P
R
V
N
-----
F
Y
E
G
L
K
N
G
------
N
L
A
S
S
I
V
H
L
-
T
--
D
N
L
D
L
I
P
G
T
F
D
L
M
L
L
P
K
L
T
R
S
W
-
T
F
E
N
E
S
--
R
L
L
A
T
L
L
A
P
L
K
S
D
-
Y
D
L
I
I
I
D
T
V
P
T
P
S
V
Y
T
N
N
A
I
V
A
S
D
Y
V
M
I
P
L
Q
A
E
E
E
S
T
-
N
N
I
Q
N
Y
I
S
Y
L
-
I
D
L
Q
E
Q
F
N
P
G
L
D
M
I
G
F
V
P
Y
L
V
D
T
D
S
A
T
I
K
S
N
L
E
----
E
L
Y
K
Q
H
--
K
E
D
N
L
V
F
---
Q
N
I
-------------
I
K
R
S
N
K
V
S
T
W
S
K
N
------
G
I
T
E
H
K
G
Y
-
D
K
K
V
L
S
M
Y
K
N
V
F
F
E
M
L
E
R
I
I
Q
L
E
N
E
KE
17
PsiBlast_PDB
68.22
23%
-76
- C2 -
3R9I
4
MIND_ECOLI
A:
[2-247]
----------------
A
R
-----
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
-
L
-
R
N
L
D
L
I
M
G
--
C
E
R
---
R
-----
V
V
Y
D
-----
F
V
N
V
I
Q
G
D
------
A
T
L
N
Q
A
L
I
K
-------
D
K
R
T
E
N
L
Y
I
L
P
A
S
Q
T
-
R
D
K
-
D
A
L
T
R
E
G
V
A
K
V
L
D
D
L
K
A
M
D
---
F
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
-
R
D
S
D
R
I
L
G
I
L
A
S
K
S
R
R
A
E
N
G
E
E
P
I
K
E
H
L
L
L
T
R
Y
N
P
G
R
V
S
R
G
D
M
L
----
S
M
E
D
V
L
----
E
I
L
R
I
---
K
L
V
G
----
V
-------
I
P
E
D
Q
S
V
L
R
A
S
N
Q
------
G
E
P
V
I
L
-
D
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
---------
15
PsiBlast_PDB
67.54
26%
-97
- C2 -
1ION
2
?
A:
[2-233]
----------------
T
R
-----
I
I
S
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
E
M
G
R
K
V
L
A
V
D
G
D
L
T
-
M
-
A
N
L
S
L
V
L
G
--
V
--
D
--
D
-----
V
N
I
T
-----
L
H
D
V
L
A
G
D
------
A
K
L
E
D
A
I
Y
M
-
T
Q
F
E
N
V
Y
I
L
P
---
G
A
V
D
W
E
H
V
I
--
K
-
A
D
P
R
K
-----
L
P
E
V
I
K
S
L
K
G
K
-
Y
D
F
I
L
I
D
C
P
A
G
L
Q
L
R
A
M
S
A
M
L
S
G
E
E
A
I
L
V
T
N
P
E
I
S
C
L
-
T
D
T
M
---
K
V
G
-
M
V
L
K
K
A
G
---
L
A
I
L
G
F
I
---------------------
L
N
R
Y
G
--
R
S
E
--
R
D
IP
P
E
A
A
Q
D
V
M
-
D
-------
V
P
L
L
A
V
I
P
E
D
P
V
I
R
E
G
T
L
E
G
I
P
A
V
K
Y
K
P
E
S
K
G
A
Q
A
F
I
K
L
A
E
E
V
D
K
L
---------
18
PsiBlast_PDB
66.64
23%
-80
- C2 -
3R9J
2
MIND_ECOLI
A:
[2-247]
----------------
A
R
-----
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
-
L
-
R
N
L
D
L
I
M
G
--
C
E
R
---
R
-----
V
V
Y
D
-----
F
V
N
V
I
Q
G
D
------
A
T
L
N
Q
A
L
I
K
-------
D
K
R
T
E
N
L
Y
I
L
P
A
S
Q
T
-
R
D
K
-
D
A
L
T
R
E
G
V
A
K
V
L
D
D
L
K
A
M
D
---
F
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
-
R
D
S
D
R
I
L
G
I
L
A
S
-------
G
E
E
P
I
K
E
H
L
L
L
T
R
Y
N
P
G
R
V
S
R
G
D
M
L
----
S
M
E
D
V
L
----
E
I
L
R
I
---
K
L
V
G
----
V
-------
I
P
E
D
Q
S
V
L
R
A
S
N
Q
------
G
E
P
V
I
L
-
D
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
---------
12
PsiBlast_PDB
64.91
28%
-65
- C2 -
1G3Q
2
?
A:
[1-233]
---------------
M
G
R
-----
I
I
S
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
L
T
-
M
-
A
N
L
S
L
V
L
G
--
V
--
D
--
D
-----
P
D
V
T
-----
L
H
D
V
L
A
G
E
------
A
N
V
E
D
A
I
Y
M
-
T
Q
F
D
N
V
Y
V
L
P
---
G
A
V
D
W
E
H
V
L
--
K
-
A
D
P
R
K
-----
L
P
E
V
I
K
S
L
K
D
K
-
F
D
F
I
L
I
D
C
P
A
G
---
L
Q
L
D
A
M
S
A
-------------
M
L
-
S
G
E
E
A
L
L
---------
V
T
N
P
--
E
I
S
C
L
T
D
T
M
K
V
-
G
I
V
L
K
K
A
G
L
A
I
LGF
V
L
N
R
Y
G
--
R
S
D
R
D
I
P
---
P
E
A
A
E
D
V
-
M
EVPLL
A
V
I
P
E
D
P
A
I
R
E
G
T
L
E
------
G
I
P
A
V
K
Y
K
P
E
S
K
G
A
K
A
F
V
K
L
A
E
E
I
E
K
L
---------
13
PsiBlast_PDB
64.75
28%
-66
- C2 -
1G3R
2
?
A:
[1-233]
---------------
M
G
R
-----
I
I
S
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
L
T
-
M
-
A
N
L
S
L
V
L
G
--
V
--
D
--
D
-----
P
D
V
T
-----
L
H
D
V
L
A
G
E
------
A
N
V
E
D
A
I
Y
M
-
T
Q
F
D
N
V
Y
V
L
P
---
G
A
V
D
W
E
H
V
L
--
K
-
A
D
P
R
K
-----
L
P
E
V
I
K
S
L
K
D
K
-
F
D
F
I
L
I
D
C
P
A
G
---
L
Q
L
D
A
M
S
A
-------------
M
L
-
S
G
E
E
A
L
L
---------
V
T
N
P
--
E
I
S
C
L
T
D
T
M
K
V
-
G
I
V
L
K
K
A
G
L
A
I
LGF
V
L
N
R
Y
G
--
R
S
D
R
D
I
P
---
P
E
A
A
E
D
V
-
M
EVPLL
A
V
I
P
E
D
P
A
I
R
E
G
T
L
E
------
G
I
P
A
V
K
Y
K
P
E
S
K
G
A
K
A
F
V
K
L
A
E
E
I
E
K
L
---------