@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_1071: (2015-12-20 )
MQENQTIPFKCPKCQEPINVSEALYKQIESENQSRFLAQQKAFEKEVNEKRAQYQSYFKNLEQKEEALKERAKEQQAQFDEAVKQASALALQDERAKIIEEARKNAFLEQQKGLELLQKELDEKSKQVQELHQKEAEIERLKRENNEAESRLKAENEKKLNEKLELEREKIEKALHEKNELKFKQQEEQLEMLRNELKNAQRKAELSSQQFQGEVQELAIEEFLRQKFPLDSVEEIKKGQRGGDCIQVVHTREFQNCGKIYYESKRTKEFQKAWVEKLKSDMREIGADVGVIVSEALPKEMERMGLFEGVWVCSFEEFKGLSAVLREGVIQVSLAKKSQENKGDKVNLLYHYLTSSEFSMQVNAIIEGFEQLRADLESEKRAMARIWKSREKQIEKVFESTINMYGSIKGIAGNAIGQVKALELGYDEGDLEN
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80.......--.90.--.......100.......110.......120.......130.---------......140.......150.......------------------160-.......170.......180-.......190-------........200.......210.......220.......230.----......240.......250.......260.......270-.........280-.........290.---...-...300-....-...310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MQENQTIPFKCPKCQEPI
N
V
S
E
A
L
Y
K
Q
I
ESE
N
Q
S
R
F
L
A
Q
Q
K
A
F
E
K
E
V
N
E
K
R
A
Q
Y
Q
S
Y
F
K
N
L
E
Q
K
E
E
A
L
K
E
R
A
K
E
Q
Q
A
Q
F
D
E
A
V
K
Q
A
S
A
--
L
A
L
Q
--
D
E
R
A
K
I
I
E
E
A
R
K
N
A
F
L
E
Q
Q
K
G
L
E
L
L
Q
K
E
L
D
E
K
S
K
Q
V
Q
E
L
H
Q
---------
K
E
A
E
I
E
R
L
K
REN
N
E
A
E
S
R
LKAE
N
E
K
K
------------------
L
N
E
-
K
L
E
L
E
R
E
K
I
E
K
A
L
H
E
K
N
E
L
K
-
F
K
Q
Q
E
E
Q
L
E
--------
M
L
R
N
E
L
K
N
A
Q
R
K
A
EL
S
S
Q
Q
F
Q
G
E
V
Q
E
L
A
I
E
E
F
L
R
QKFPL
D
S
V
----
E
E
I
K
KGQRGG
D
C
I
Q
V
V
H
T
R
E
F
Q
N
C
G
K
I
Y
Y
E
S
K
R
T
K
E
F
---
Q
K
A
W
V
E
K
L
K
S
---
D
M
R
E
IGA
D
V
G
V
I
V
---
S
E
A
-
L
P
K
E
M
E
-RMGL-FE
G
V
W
V
C
S
F
E
E
F
K
G
L
S
A
V
L
REG
V
I
Q
V
S
LAKKSQENKGD
K
V
N
L
L
Y
H
YLTSS
E
F
S
M
Q
V
N
A
I
I
E
G
F
E
Q
L
R
A
D
L
E
S
E
K
R
A
M
A
R
I
W
K
S
R
E
K
Q
I
E
K
V
F
E
S
T
I
N
M
Y
GSIKGIAGNAI
G
Q
V
K
A
L
E
LGYDEGDLEN
19
PsiBlast_PDB
78.58
27%
25
- C3 -
1DG3
-
GBP1_HUMAN
A:
[440-582]
--------------------------------------------------------------------------------------------
L
Q
--
D
L
K
K
K
Y
Y
E
E
P
R
K
G
I
Q
A
E
-----
E
I
L
Q
T
Y
L
K
S
K
E
S
M
T
D
A
I
L
Q
T
DQTLT
E
K
E
K
E
I
E
V
E
R
V
K
A
E
S
A
Q
A
S
A
K
M
L
H
E
M
Q
R
K
N
E
Q
M
M
E
Q
K
E
R
S
Y
Q
E
H
L
K
Q
L
T
E
-
K
M
E
N
D
R
V
Q
L
L
K
E
Q
E
R
T
L
A
L
K
-
L
Q
E
Q
E
Q
L
L
K
E
GF
Q
K
E
S
R
I
M
K
N
E
I
Q
D
L
Q
T
K
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
69.71
27%
30
- C3 -
1F5N
-
GBP1_HUMAN
A:
[440-582]
--------------------------------------------------------------------------------------------
L
Q
--
D
L
K
K
K
Y
Y
E
E
P
R
K
G
I
Q
A
E
-----
E
I
L
Q
T
Y
L
K
S
K
E
S
M
T
D
A
I
L
Q
T
DQTLT
E
K
E
K
E
I
E
V
E
R
V
K
A
E
S
A
Q
A
S
A
K
M
L
H
E
M
Q
R
K
N
E
Q
M
M
E
Q
K
E
R
S
Y
Q
E
H
L
K
Q
L
T
E
-
K
M
E
N
D
R
V
Q
L
L
K
E
Q
E
R
T
L
A
L
K
-
L
Q
E
Q
E
Q
L
L
K
E
GF
Q
K
E
S
R
I
M
K
N
E
I
Q
D
L
Q
T
K
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
Fugue
53.28
14%
19
- C3 -
4CPC
-
SYCP3_HUMAN
A:
[18-160]
--------------------------------------
I
N
K
A
L
L
A
K
R
K
R
L
E
M
Y
T
K
A
S
L
K
T
S
N
Q
K
I
E
H
V
W
K
T
Q
Q
D
Q
R
Q
K
L
N
Q
E
Y
S
Q
Q
F
L
--
T
L
F
Q
Q
W
D
L
D
M
Q
K
A
E
E
Q
E
E
K
I
L
N
M
F
R
Q
Q
Q
K
I
L
Q
Q
S
R
I
V
Q
S
Q
R
L
K
T
I
K
Q
---------
L
Y
E
Q
F
I
K
S
M
E
E
L
E
K
N
H
D
N
L
L
T
G
A
Q
N
E
------------------
F
K
K
-
E
M
A
M
L
Q
K
K
I
M
M
E
T
Q
Q
Q
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
67
Fugue
51.50
13%
73
- C3 -
3FRV
-
CHMP3_HUMAN
A:
[8-140]
---------------------------------------------------------------
Q
E
K
P
P
K
E
L
V
N
E
W
S
L
K
I
R
K
E
M
R
V
V
D
R
Q
I
R
D
I
Q
--
R
E
E
E
K
V
K
R
S
V
K
D
A
A
K
K
G
Q
K
D
V
C
I
V
L
A
K
E
M
I
R
S
R
K
A
V
S
K
L
Y
A
---------
S
K
A
H
M
N
S
V
L
M
G
M
K
N
Q
L
A
V
L
R
V
A
G
S
L
Q
------------------
K
S
T
-
E
V
M
K
A
M
Q
S
L
V
K
I
P
E
I
Q
A
T
M
R
E
L
S
K
E
M
M
K
A
G
--------
I
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64
Fugue
49.70
16%
75
- C3 -
4JPN
-
H_BPPHS
A:
[2-76]
-----------------------------------------------------------------------------------------------------------------------------------
V
D
A
G
F
E
---------
N
Q
K
E
L
T
K
M
Q
L
D
N
Q
K
E
I
A
E
M
Q
N
E
T
Q
K
E
------------------
I
A
G
I
Q
S
A
T
S
R
Q
N
T
K
D
Q
V
Y
A
Q
N
E
M
L
-
A
Y
Q
Q
K
E
S
T
A
--------
R
V
A
S
I
M
E
N
T
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
66
Fugue
48.95
27%
132
- C3 -
1YSM
-
CYBP_MOUSE
A:
[1-55]
--------------------------------------------------------------------------------------------------------------------------------------------------
M
A
S
V
L
E
E
L
Q
K
D
L
E
E
V
K
V
L
L
E
K
S
T
R
K
R
------------------
L
R
D
-
T
L
T
S
E
K
S
K
I
E
T
E
L
K
N
K
M
Q
Q
K
-
S
Q
K
K
P
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
Fugue
48.86
12%
47
- C3 -
4LTB
-
?
A:
[2-172]
----------------
S
L
S
Q
A
S
A
D
L
E
A
T
L
R
H
K
L
T
V
M
Y
S
Q
I
N
G
A
S
R
A
L
D
D
V
R
N
R
Q
Q
D
V
R
M
T
A
N
R
K
V
E
Q
L
Q
Q
E
Y
T
E
M
K
A
L
L
D
A
S
E
T
T
S
T
R
--
K
I
K
E
--
E
E
K
R
V
N
S
K
F
D
T
I
Y
Q
I
L
L
K
K
K
S
E
I
Q
T
L
K
E
E
I
E
Q
S
L
T
K
R
D
E
F
E
---------
F
L
E
K
A
S
K
L
R
G
I
S
T
K
P
V
Y
I
P
E
V
E
L
N
H
K
------------------
L
I
K
-
G
I
H
Q
S
T
I
D
L
K
N
E
L
K
Q
C
I
G
R
L
-
Q
E
L
T
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
48.03
30%
52
- C3 -
4I8C
5
NIKA_ECOLI
A:
[349-411]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
A
L
---
S
K
S
M
A
E
I
I
Q
A
---
D
M
R
Q
I
G
A
D
V
S
L
I
G
E
E
E
S
S
I
-
Y
A
R
Q
R
D
G
R
F
G
M
I
F
H
R
T
W
G
A
P
Y
D
P
H
A
F
L
S
S
M
R
V
P
S
H
A
D
F
Q
A
Q
Q
G
L
A
D
K
P
L
I
D
K
E
I
G
E
V
L
A
T
H
D
E
T
Q
R
Q
A
L
Y
R
D
I
L
T
R
L
H
D
E
A
V
Y
L
P
I
S
Y
I
S
M
M
V
V
S
K
P
E
L
G
N
I
P
Y
A
P
I
A
T
E
I
P
F
E
Q
I
K
P
V
--------------------
6
PsiBlast_PDB
47.96
30%
53
- C3 -
3E3K
2
NIKA_ECOLI
A:
[349-411]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
A
L
---
S
K
S
M
A
E
I
I
Q
A
---
D
M
R
Q
I
G
A
D
V
S
L
I
G
E
E
E
S
S
I
-
Y
A
R
Q
R
D
G
R
F
G
M
I
F
H
R
T
W
G
A
P
Y
D
P
H
A
F
L
S
S
M
R
V
P
S
H
A
D
F
Q
A
Q
Q
G
L
A
D
K
P
L
I
D
K
E
I
G
E
V
L
A
T
H
D
E
T
Q
R
Q
A
L
Y
R
D
I
L
T
R
L
H
D
E
A
V
Y
L
P
I
S
Y
I
S
M
M
V
V
S
K
P
E
L
G
N
I
P
Y
A
P
I
A
T
E
I
P
F
E
Q
I
K
P
V
--------------------
5
PsiBlast_PDB
47.53
30%
51
- C3 -
3DP8
3
NIKA_ECOLI
A:
[349-411]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
A
L
---
S
K
S
M
A
E
I
I
Q
A
---
D
M
R
Q
I
G
A
D
V
S
L
I
G
E
E
E
S
S
I
-
Y
A
R
Q
R
D
G
R
F
G
M
I
F
H
R
T
W
G
A
P
Y
D
P
H
A
F
L
S
S
M
R
V
P
S
H
A
D
F
Q
A
Q
Q
G
L
A
D
K
P
L
I
D
K
E
I
G
E
V
L
A
T
H
D
E
T
Q
R
Q
A
L
Y
R
D
I
L
T
R
L
H
D
E
A
V
Y
L
P
I
S
Y
I
S
M
M
V
V
S
K
P
E
L
G
N
I
P
Y
A
P
I
A
T
E
I
P
F
E
Q
I
K
P
---------------------
14
PsiBlast_PDB
47.26
30%
45
- C3 -
4DCY
4
NIKA_ECOLI
A:
[349-411]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
A
L
---
S
K
S
M
A
E
I
I
Q
A
---
D
M
R
Q
I
G
A
D
V
S
L
I
G
E
E
E
S
S
I
-
Y
A
R
Q
R
D
G
R
F
G
M
I
F
H
R
T
W
G
A
P
Y
D
P
H
A
F
L
S
S
M
R
V
P
S
H
A
D
F
Q
A
Q
Q
G
L
A
D
K
P
L
I
D
K
E
I
G
E
V
L
A
T
H
D
E
T
Q
R
Q
A
L
Y
R
D
I
L
T
R
L
H
D
E
A
V
Y
L
P
I
S
Y
I
S
M
M
V
V
S
K
P
E
L
G
N
I
P
Y
A
P
I
A
T
E
I
P
F
E
Q
I
K
P
V
--------------------
33
HHSearch
47.15
11%
-21
- C3 -
1Y88
7
Y1548_ARCFU
A:
[16-123]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
Y
F
Q
G
H
M
V
A
R
L
L
E
E
H
-
G
F
E
T
K
T
NVI
V
Q
G
N
C
V
E
Q
E
I
D
V
V
A
E
R
D
---
G
---
E
R
Y
M
I
E
C
K
F
H
N
I
P
VYT
G
L
K
E
A
M
Y
T
Y
A
R
F
L
D
V
E
K
H
G
F
T
Q
P
W
I
F
---
T
N
T
K
F
S
E
E
A
K
-
K
Y
A
G
-
C
V
G
I
K
L
T
G
W
S
Y
P
E
K
E
G
I
E
V
L
L
E
S
K
G
L
Y
P
I
T
I
L
R
I
D
K
E
V
L
D
E
L
V
R
A
G
L
V
F
C
R
D
V
V
S
A
G
E
E
K
L
R
E
I
G
L
S
A
K
K
A
R
E
V
I
A
E
A
K
K
V
I
G
G
S
------------------------------------------
1
PsiBlast_PDB
46.95
30%
41
- C3 -
1UIU
-
NIKA_ECOLI
A:
[349-411]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
A
L
---
S
K
S
M
A
E
I
I
R
A
---
D
M
R
Q
I
G
A
D
V
S
L
I
G
E
E
E
S
S
I
-
Y
A
R
Q
R
D
G
R
F
G
M
I
F
H
R
T
W
G
A
P
Y
D
P
H
A
F
L
S
S
M
R
V
P
S
H
A
D
F
Q
A
Q
Q
G
L
A
D
K
P
L
I
D
K
E
I
G
E
V
L
A
T
H
D
E
T
Q
R
Q
A
L
Y
R
D
I
L
T
R
L
H
D
E
A
V
Y
L
P
I
S
Y
I
S
M
M
V
V
S
K
P
E
L
G
N
I
P
Y
A
P
I
A
T
E
I
P
F
E
Q
I
K
P
---------------------
16
PsiBlast_PDB
46.78
30%
52
- C3 -
4I9D
4
NIKA_ECOLI
A:
[349-411]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
A
L
---
S
K
S
M
A
E
I
I
Q
A
---
D
M
R
Q
I
G
A
D
V
S
L
I
G
E
E
E
S
S
I
-
Y
A
R
Q
R
D
G
R
F
G
M
I
F
H
R
T
W
G
A
P
Y
D
P
H
A
F
L
S
S
M
R
V
P
S
H
A
D
F
Q
A
Q
Q
G
L
A
D
K
P
L
I
D
K
E
I
G
E
V
L
A
T
H
D
E
T
Q
R
Q
A
L
Y
R
D
I
L
T
R
L
H
D
E
A
V
Y
L
P
I
S
Y
I
S
M
M
V
V
S
K
P
E
L
G
N
I
P
Y
A
P
I
A
T
E
I
P
F
E
Q
I
K
P
V
--------------------
9
PsiBlast_PDB
46.60
30%
52
- C3 -
3MVY
4
NIKA_ECOLI
A:
[349-411]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
A
L
---
S
K
S
M
A
E
I
I
Q
A
---
D
M
R
Q
I
G
A
D
V
S
L
I
G
E
E
E
S
S
I
-
Y
A
R
Q
R
D
G
R
F
G
M
I
F
H
R
T
W
G
A
P
Y
D
P
H
A
F
L
S
S
M
R
V
P
S
H
A
D
F
Q
A
Q
Q
G
L
A
D
K
P
L
I
D
K
E
I
G
E
V
L
A
T
H
D
E
T
Q
R
Q
A
L
Y
R
D
I
L
T
R
L
H
D
E
A
V
Y
L
P
I
S
Y
I
S
M
M
V
V
S
K
P
E
L
G
N
I
P
Y
A
P
I
A
T
E
I
P
F
E
Q
I
K
P
---------------------
10
PsiBlast_PDB
46.57
30%
49
- C3 -
3MVZ
5
NIKA_ECOLI
A:
[349-411]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
A
L
---
S
K
S
M
A
E
I
I
Q
A
---
D
M
R
Q
I
G
A
D
V
S
L
I
G
E
E
E
S
S
I
-
Y
A
R
Q
R
D
G
R
F
G
M
I
F
H
R
T
W
G
A
P
Y
D
P
H
A
F
L
S
S
M
R
V
P
S
H
A
D
F
Q
A
Q
Q
G
L
A
D
K
P
L
I
D
K
E
I
G
E
V
L
A
T
H
D
E
T
Q
R
Q
A
L
Y
R
D
I
L
T
R
L
H
D
E
A
V
Y
L
P
I
S
Y
I
S
M
M
V
V
S
K
P
E
L
G
N
I
P
Y
A
P
I
A
T
E
I
P
F
E
Q
I
K
P
---------------------
13
PsiBlast_PDB
46.55
30%
43
- C3 -
4DCX
5
NIKA_ECOLI
A:
[349-411]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
A
L
---
S
K
S
M
A
E
I
I
Q
A
---
D
M
R
Q
I
G
A
D
V
S
L
I
G
E
E
E
S
S
I
-
Y
A
R
Q
R
D
G
R
F
G
M
I
F
H
R
T
W
G
A
P
Y
D
P
H
A
F
L
S
S
M
R
V
P
S
H
A
D
F
Q
A
Q
Q
G
L
A
D
K
P
L
I
D
K
E
I
G
E
V
L
A
T
H
D
E
T
Q
R
Q
A
L
Y
R
D
I
L
T
R
L
H
D
E
A
V
Y
L
P
I
S
Y
I
S
M
M
V
V
S
K
P
E
L
G
N
I
P
Y
A
P
I
A
T
E
I
P
F
E
Q
I
K
P
---------------------
3
PsiBlast_PDB
46.20
30%
41
- C3 -
3MZB
5
NIKA_ECOLI
A:
[349-411]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
A
L
---
S
K
S
M
A
E
I
I
Q
A
---
D
M
R
Q
I
G
A
D
V
S
L
I
G
E
E
E
S
S
I
-
Y
A
R
Q
R
D
G
R
F
G
M
I
F
H
R
T
W
G
A
P
Y
D
P
H
A
F
L
S
S
M
R
V
P
S
H
A
D
F
Q
A
Q
Q
G
L
A
D
K
P
L
I
D
K
E
I
G
E
V
L
A
T
H
D
E
T
Q
R
Q
A
L
Y
R
D
I
L
T
R
L
H
D
E
A
V
Y
L
P
I
S
Y
I
S
M
M
V
V
S
K
P
E
L
G
N
I
P
Y
A
P
I
A
T
E
I
P
F
E
Q
I
K
P
---------------------
62
Fugue
46.14
11%
78
- C3 -
1XAW
-
OCLN_HUMAN
A:
[416-522]
-------------------------------------
W
I
R
E
Y
P
P
I
T
S
D
Q
Q
R
Q
L
Y
K
R
N
F
D
T
G
L
Q
E
Y
K
S
L
Q
S
V
L
D
E
I
N
K
E
L
S
R
L
D
K
E
L
D
D
--
Y
R
E
E
--
S
E
E
Y
M
A
A
A
D
E
Y
N
R
L
K
Q
V
K
G
------
S
A
D
Y
K
S
K
K
N
H
C
K
Q
L
K
S
---------
K
L
S
H
I
K
K
M
V
G
D
Y
D
R
Q
K
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68
Fugue
46.03
27%
190
* C3 *
3VOP
4
A27_VACCW
A:
[25-64]
----------------------------------------------------------------------------------------------------------------------
E
T
L
K
Q
R
L
T
N
L
E
K
K
I
T
N
V
T
T
---------
K
F
E
Q
I
E
K
A
A
K
R
N
D
E
V
L
F
R
L
E
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------